Title: Method and Apparatus for Collecting and/or Separating Solids from Liquids

Applicant/Assignee: ULTRA AQUATIC TECHNOLOGY PTY LTD

Application No.: 10/572822   Filing Date: 21/Sep/2004

Abstract:

Apparatus (10) for collecting solids selling on the bottom of a liquid reservoir and/or floating solids, the apparatus (10) having a hollow suction head (23) and at least one outlet duct (26) extending from the suction head (23). Air can be supplied to the suction head (23) to create a suction pressure in the suction head (23) to cause settling solids beneath the suction head (23) to pass along the outlet duct or ducts (26). The suction head (23) may be connected to a collector (11) which is provided with a float (21) to support the collector (11) at the surface of the liquid, and the outlet duct or ducts (26) are connected to the collector (11) which collects the solids. The collector (11) may also have an inlet to collect floating solids.

Priority: AU20030905127 Applic. Date: 2003-09-22; WO2004AU01282 Applic. Date: 2004-09-21

Inventor: NIELSEN IAN BRADLEY [AU]

Title: SKIN AND SURFACE DISINFECTANT COMPOSITIONS CONTAINING BOTANICALS

Applicant/Assignee:

Application No.: 12/134918   Filing Date: 06/Jun/2008

Abstract:

The present invention relates to a skin or surface disinfectant composition with broad spectrum antimicrobial activity comprising one or more essential oil (and/or one or more component thereof) and one or more fruit acid. The compositions of the invention may be used as non-toxic alternatives to conventional disinfectants or may be added to other antimicrobial agents to enhance their activity. The invention provides effective alternatives to harsher products which may be particularly useful in personal care and household products and where children and/or pet exposure may be a concern.

Priority: US2008-016788 Applic. Date: 2008-01-18; US20070953654P Applic. Date: 2007-08-02; US20070945288P Applic. Date: 2007-06-20

Inventor: MODAK SHANTA M [US]; BAIJU NAYANA [US]; CARAOS LAUSERPINA A [US]

Title: Method of treating dyshidrosis(pompholyx) and related dry skin disorders

Applicant/Assignee:

Application No.: 12/008719   Filing Date: 11/Jan/2008

Abstract:

This invention discloses a method of use for a topical herbal formulation alone or in combination with oral administration of niacin (preferably a flush preparation) to prevent and/or treat dyshidrosis (pompholyx) and related skin diseases. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders.

The active ingredients within the formula include a combination of dry, aqueous, acid and alcohol extracts of black walnut hull (Juglans nigra), wormwood (Artemisia absinthium), tumeric rhizome (Curcuma longa), garlic (Allium sativum), two or more herbal antibacterial agents from the group consisting of chamomile (Matricaria Chamomile), licorice root (Glycyrrhiza glabra), St Johns wort (Hypericum perforatum), clove (Syzygium aromaticum), nutmeg (Myristica fragans), ginger (Zingiber officinale), frankincense (Boswellia carteri) and myrrh (Commiphora molmol), further combined with aloe vera and niacin.

Priority: US2004-801520 Applic. Date: 2004-03-16; US20030456817P Applic. Date: 2003-03-21

Inventor: MAZZIO ELIZABETH [US]; SOLIMAN KARAM [US]

Title: SUCKBACK PREVENTION DEVICE FOR SINGLE USE HIGH-SPEED TURBINE DENTAL DRILL HANDPIECE

Applicant/Assignee: BEIJING NORTH POLE DENTAL HANDPIECES CO., LTD

Application No.: 12/208480   Filing Date: 11/Sep/2008

Abstract:

A suckback prevention device for single use high-speed turbine dental drill handpiece, installed at the side assembled with the drilling needle of the head housing of the high-speed turbine dental drill handpiece which comprises a head, a drilling needle (3), a front handle (1), and a back handle (2). A powered wind wheel (7) and a wind wheel axle (15) driving the rotation of the drilling needle (3) are installed in the clearance space between the head housing (4) and the head cover (8). The wind wheel axle (15) is supported by the bearing (6). An O-shaped vibration reduction ring is disposed between the bearing (6) and the head housing (4). The upper end of the wind wheel axle (15) is connected orderly to the button cap spring (10) and the button cap (9). A water passage (19), an air passage (20), and a driving wind wheel air passage (12) are set at the neck portion of the head. The compressed air inlet (11) of the driving wind wheel is located in the powered wind wheel (7). The lower end of the wind wheel axle (15) is hidden inside of the head housing (4) and is connected with the drilling needle (3). The edge of the head housing (4) relative to the wind wheel axle (15) and the drilling needle (3) is an annular opening in a two-step profile shape. An elastic bowl-shaped axle shroud (14) is buckled in the inner step of the head housing (4). An eyelet for the drilling needle is set at the center of the axle shroud (14), and the size of the eyelet is slightly larger than the outer diameter of the drilling needle. An annular screw (13) is screwed connected to the outer step of the head housing (4).

Priority: CN20061200741 Applic. Date: 2006-07-25; WO2007CN70113 Applic. Date: 2007-06-14

Inventor: ZHANG FUDONG [CN]

Title: METHOD AND COMPOSITIONS FOR NUCLEIC ACID AMPLIFICATION

Applicant/Assignee: APPLERA CORPORATION

Application No.: 12/140142   Filing Date: 16/Jun/2008

Abstract:

The present teachings provide methods, compositions, and kits for nucleic acid amplification. In some embodiments of the present teachings, amplification reactions are performed with at least one high stability primer. In some embodiments, the present teachings provide a method comprising a high stability primer for amplification of a nucleic acid sequence in a sample comprising a target nucleic acid sequence and a PCR inhibitor.

Priority: US20070944708P Applic. Date: 2007-06-18

Inventor: MULERO JULIO J [US]; HENNESSY LORI K [US]

Title: Compositions and methods for treating medical conditions

Applicant/Assignee:

Application No.: 12/215005   Filing Date: 24/Jun/2008

Abstract:

The invention features methods, compositions, and kits for the treatment of pain or pruritus in a patient. In one embodiment, the methods, compositions, and kits of the invention provide for a combination therapy including a tricyclic compound and a tetra-substituted pyrimidopyrimidine.

Priority: US20070937282P Applic. Date: 2007-06-26

Inventor: LESSEM JAN [US]

Title: Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient

Applicant/Assignee: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY THE TOHO UNIVERSITY

Application No.: 11/663748   Filing Date: 16/Sep/2005

Abstract:

It is intended to find a compound that is structurally simpler than yohimbine, a pentacyclic condensed heterocyclic compound, and has an effect similar to that of yohimbine. The present invention relates to a pharmaceutical or food composition for alpha2 receptor blockage comprising a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: (wherein R1 represents a hydrogen, alkyl group, alkenyl group, alkynyl group, aromatic group, aralkyl group, acyl group, arylsulfonyl group, alkylsulfonyl group, or hydroxyl group

R2 represents a hydrocarbon group

R3, R4, R5, R6, and R7 are the same or different and represent a hydrogen, halogen, alkyl group, or alkoxy group

R8 represents a hydrogen or acyl group

n represents an integer of 1 to 6

and a and b are the same or different and represent 1 or 0).

Priority: JP20040280104 Applic. Date: 2004-09-27; WO2005JP17109 Applic. Date: 2005-09-16

Inventor: SOMEI MASANORI [JP]; SHIGENOBU KOKI [JP]; TANAKA YOSHIO [JP]

Title: Diphenyl Urea Derivatives

Applicant/Assignee: ARIPIDA AG ARPIDA AG

Application No.: 12/096831   Filing Date: 08/Dec/2006

Abstract:

The invention relates to novel specifically trifluoromethyl and halogen substituted 1,3-diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects like the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as anti-infectives.

Priority: WO2005EP13345 Applic. Date: 2005-12-13; WO2006EP11795 Applic. Date: 2006-12-08

Inventor: LOEWE RALF [CH]; LOCIURO SERGIO [CH]; HAWSER STEPHEN [FR]; SCHMITT LAURENT [FR]

Title: Dental Compositions and Initiator Systems with Polycyclic Aromatic Component

Applicant/Assignee:

Application No.: 12/159250   Filing Date: 22/Dec/2006

Abstract:

The invention features a polymerizable composition that comprises a free-radically polymerizable acidic resin, and a photoinitiator system comprising a polycyclic aromatic component. The photoinitiator system may also contain a visible light sensitizer, an iodonium salt, and a tertiary amine.

Priority: US20050754952P Applic. Date: 2005-12-29; WO2006US49249 Applic. Date: 2006-12-22

Inventor: CRAIG BRADLEY D [US]; SHUKLA BRIAN A [US]; OXMAN JOEL D [US]; RUSSELL VICTORIA A [US]

Title: METHOD OF MANUFACTURING DENTAL INSTRUMENTS FROM SUPER-ELASTIC ALLOYS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 12/210539   Filing Date: 15/Sep/2008

Abstract:

Dental instruments and appliances are manufactured from a superelastic alloy, which includes atoms from the group IVB and group VB transition metals and oxygen so as to exhibit superior strength and flexibility. The metal alloys are cold worked to increase the tensile strength of the dental instruments and appliances. Cold working the metal also increases the flexibility of the dental instruments and appliances and prevents work hardening. Dental instruments made from the superelastic alloy exhibit higher strength, flexibility, resistance to work hardening, and biocompatibility compared to dental instruments made from nickel-titanium alloys. In one particular example a super-elastic endodontic file is described.

Priority: US2005-176839 Applic. Date: 2005-07-07; US20040586738P Applic. Date: 2004-07-09

Inventor: FISCHER DAN E [US]

Title: Composition, Comprising Hydrofluoric Acid, for Inhibiting Dental Erosion

Applicant/Assignee: IN 2 GROUP AS

Application No.: 11/596104   Filing Date: 18/May/2005

Abstract:

The present invention relates to a composition, for inhibiting dental erosion, and the use thereof. The composition comprises an aqueous solution of hydrofluoric acid, in which the concentration of hydrofluoric acid is 0.05%-2.00% and the pH is between 2.5 and 4.5.

Priority: NO20040002027 Applic. Date: 2004-05-14; WO2005NO00167 Applic. Date: 2005-05-18

Inventor: ROLLA GUNNAR [NO]; THRANE PER STANLEY [NO]

Title: Toothpaste Comprising Calcium Carbonate and Zinc Citrate

Applicant/Assignee:

Application No.: 11/658957   Filing Date: 05/Jul/2005

Abstract:

Toothpaste and method for making such, the toothpaste comprising calcium carbonate as abrasive, water and zinc salt substantially all of which is in the form of water-solubilised zinc citrate.

Priority: EP20040254661 Applic. Date: 2004-08-03; WO2005EP07319 Applic. Date: 2005-07-05

Inventor: WATERFIELD PHILIP CHRISTOPHER [GB]

Title: Oral Composition

Applicant/Assignee:

Application No.: 11/658956   Filing Date: 13/Jul/2005

Abstract:

A visually clear gel toothpaste composition comprising a sparingly soluble divalent metal salt, characterised in that the sparingly soluble divalent metal salt is fully solubilised by a chelating agent for the metal salt, the chelating agent having a log Ks1 for the divalent metal ion as herein defined of from 3.0 to 7.0.

Priority: EP20040254662 Applic. Date: 2004-08-03; EP20040254661 Applic. Date: 2004-08-03; EP20040257063 Applic. Date: 2004-11-15; EP20040257064 Applic. Date: 2004-11-15; EP20050250131 Applic. Date: 2005-01-13; WO2005EP07722 Applic. Date: 2005-07-13

Inventor: WATERFIELD PHILIP CHRISTOPHER [GB]

Title: Compositions effective in altering the perception of malodor

Applicant/Assignee: PATUS LTD

Application No.: 12/230746   Filing Date: 04/Sep/2008

Abstract:

A method of modifying perception of a malodor, such as the stench associated with putrefying flesh, by selectively affecting specific olfactory receptors in an individual is disclosed. Disclosed are articles of manufacture and especially innovative compositions effective in implementing the method of the present invention including at least three plant extracts.

Priority: US2006-579842 Applic. Date: 2006-05-17; WO2004IL01047 Applic. Date: 2004-11-15; US20030520319P Applic. Date: 2003-11-17; US20030526600P Applic. Date: 2003-12-04

Inventor: PINNEY VIRGINIA RUTH [US]

Title: Silicas

Applicant/Assignee: INEOS SILICAS LIMITED

Application No.: 12/158234   Filing Date: 12/Dec/2006

Abstract:

Priority: GB20050025369 Applic. Date: 2005-12-14; WO2006GB04649 Applic. Date: 2006-12-12

Inventor: STANIER PETER WILLIAM [GB]

Title: Coating For Implants and Implants With Improved Osteointegration, and Manufacturing Method

Applicant/Assignee: N0LABS AB

Application No.: 12/065601   Filing Date: 13/Feb/2006

Abstract:

A coating on an implant, said implant being intended for implantation in/on an implantation area, is provided. The coating comprises nitric oxide (NO) for obtaining an anti-viral, anti-fungal, and anti-bacterial effect, and for promotion of osteo-integration of the implant, bone healing, bone growth, and wound healing at said implantation area. A nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of a therapeutic dosage of nitric oxide (NO). An implant and a kit of implants, comprising said coating are also provided. Furthermore, a manufacturing method for the implant is disclosed.

Priority: US20050716192P Applic. Date: 2005-09-12; WO2006EP50903 Applic. Date: 2006-02-13

Inventor: PETERS TOR [CH]

Title: NON-INVASIVE METHOD FOR TREATING PERIODONTAL DISEASE

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/141055   Filing Date: 17/Jun/2008

Abstract:

The present invention is a method of non-invasive treatment of periodontal disease using ultrasonic waves. The treatment involves placing a tray, covering a metal fork, over the arch intended to be treated. The tray holds the metal fork to the teeth and gingival surface. The metal fork is connected to at least one ultrasonic transducer, which is in turn connected to a control unit that controls the delivery of ultrasonic energy. Both upper and lower arches can be treated simultaneously. The tray(s) may be filled with a therapeutic gel or the patient's own saliva maybe permitted to fill the tray and serve as a conductive gel. The ultrasonic waves, both alone or with a therapeutic gel, and heal the diseased tissue without surgery or curettage. Treatment may be repeated as needed or it may be used as a preventative measure with lesser treatment time.

Priority: US2007-961557 Applic. Date: 2007-12-20; US2004-913702 Applic. Date: 2004-08-06; US20080050472P Applic. Date: 2008-05-05

Inventor: JENSEN STEVEN D [US]; CAO DENSEN [US]

Title: Method and composition for adhering to tooth structure

Applicant/Assignee:

Application No.: 12/231928   Filing Date: 08/Sep/2008

Abstract:

A dental adhesive composition has an adhesive component and an activator component. The adhesive composition has a volatile organic solvent component, one or more polymerizable (meth)acrylate compounds optionally containing fillers, and a polymerization photoinitiator. The adhesive component may also be a substantially homogeneous mixture of one or more polymerizable (meth)acrylate compounds and an effective amount of a photoinitiator, without a solvent. The activator component includes an aromatic sulfinate salt and an activator component solvent. A method for adhering a restorative to a dental surface includes preparing the surface for restoration

applying a mixture of an adhesive component and an activator component to the prepared cavity, thereby forming a coated cavity surface

and, applying a direct or indirect dental restorative to the coated cavity surface.

Priority: US2007-700461 Applic. Date: 2007-01-31; US2004-945453 Applic. Date: 2004-09-20; US1998-107913 Applic. Date: 1998-06-30

Inventor: SANG JUNJIE [US]; HAMMESFAHR PAUL D [US]

Title: STRENGTHENED, PRESSABLE CERAMIC COMPOSITIONS FOR DENTAL PURPOSES

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 12/211135   Filing Date: 16/Sep/2008

Abstract:

Pressable glass-ceramic compositions for dental purposes of the composition I, II or III I II III

colname="4" colwidth="42pt" align="center"/>

ZrO2 17-70% ZrO2/Al2O3 15-70% Al2O3 15-70% SiO2 17-59% SiO2 17-59% SiO2 17-59% Al2O3 2-15% ZrO2 2-15% ZrO2 2-15% Y2O3 0-6% Y2O3 0-6% Y2O3 0-6% K2O 3-12.5% K2O 3-12.5% K2O 3-12.5%

Na2O 0.2-8.5% Na2O 0.2-8.5% Na2O 0.2-8.5% Li2O 0-1.5% Li2O 0-1.5% Li2O 0-1.5% CaO 0.3-2% CaO 0.3-2% CaO 0.3-2% B2O3 0.1-5% B2O3 0.1-5% B2O3 0.1-5% F 0-2.5% F 0-2.5% F 0-2.5% CeO2 0.2-2% CeO2 0.2-2% CeO2 0.2-2% TiO2 0-1.5%

TiO2 0-1.5% TiO2 0-1.5%

are particularly suitable for the manufacturing of ceramic veneer frames.

Priority: DE200410010138 Applic. Date: 2004-02-27; US2005-052396 Applic. Date: 2005-02-07

Inventor: STEIDL JURGEN [DE]

Title: DENTAL COMPOSITIONS CONTAINING A SURFACE-MODIFIED FILLER

Applicant/Assignee:

Application No.: 11/997788   Filing Date: 31/Jul/2006

Abstract:

The present invention features ionomer compositions containing a filler surface modified with a polyacid. The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.

Priority: US20050706180P Applic. Date: 2005-08-05; WO2006EP07557 Applic. Date: 2006-07-31

Inventor: ECKHARDT GUNTHER [DE]; MIKULLA MARKUS [DE]; PEEZ ROBERT F [DE]; BISSINGER PETER [DE]; GOTTSCHALK-GAUDIG GABRIELE [DE]

Title: Coated colloidal ground plant materials

Applicant/Assignee: PHILIP MORRIS USA INC

Application No.: 12/155227   Filing Date: 30/May/2008

Abstract:

A method of providing a comestible plant material taken orally by coating a micronized plant material with a first layer of polysaccharides or proteins, then a second layer of polysaccharides or proteins is disclosed. A bi-encapsulated plant material produced by this process is also disclosed.

Priority: US20070924826P Applic. Date: 2007-06-01

Inventor: SENGUPTA TAPASHI [US]; MISHRA MUNMAYA K [US]; SWEENEY WILLIAM R [US]; FERNANDEZ DOUGLAS A [US]

Title: DEVICE FOR CLEANING INTERDENTAL SPACES

Applicant/Assignee:

Application No.: 12/239168   Filing Date: 26/Sep/2008

Abstract:

Individually packaged coils of dental floss are packed in a succession of separable. The package can be a tubular sheet structure with segments formed between transverse lines of attachment at which the floss is cut and the segments are separable by a lateral perforation. Tearing a separated single segment in half allows the floss to be extended between the free ends of the floss, each captured in the remaining portions of the weld lines at opposite ends of the segment. The segments can be formed from two facing sheets with welds along both lateral edges and across the transverse lines between segments. Alternatively, an integral sheet can be folded to form one lateral edge and attached at the other edge. The sheet material can be polymer coated paper or a transparent plastic.

Priority: WO2006RU00153 Applic. Date: 2006-03-31

Inventor: LYULYEV VYACHESLAV MIKHAILOVICH [RU]; PAVELKO SERGEY MAIKOVICH [RU]; SHKURENKO SVETLANA IVANOVNA [RU]

Title: Oral cavity care curative and prophylactic composition

Applicant/Assignee:

Application No.: 12/094605   Filing Date: 19/Sep/2008

Abstract:

The invention relates to stomatology and perfume industry in particular to therapeutic formulation for oral cavity care. The invention refers to oral hygiene means and can be applied for preparation of medical and prophylactic tooth-pastes, gels, liquids for oral care as well as other compositions like chewing gums, jellies, etc. Formulation containing orally applicable active and inert components involves bromelain in amount of 0.01/1 wt %, xylitol 1.5/20 wt %. At best bromelain content is 0.1-0.8 wt %, xylitol content-2.2-18 wt %. For attaining remineralizing effect formulation contains anti-carious mineral additive 0.05-3.0 wt % of the list of active components. At best anti-carious mineral additive content is 0.2-2.5 wt %. There are used calcium glycerophosphate and inorganic or organic magnesium salt as anti-carious mineral additive. It is acceptable to use sodium monofluorphosphate, potassium monofluorphosphate, calcium monofluorphosphate or magnesium monofluorphosphate in amount of 0.5-1.5 wt % as anti-carious mineral additive Optimum concentration is 0.8-1.1 wt %.

Priority: WO2005RU00601 Applic. Date: 2005-11-25

Inventor: MANASHEROV TAMAZI OMAROVICH [RU]; MATELO SVETLANA KONSTANTINOVNA [RU]; GROSSER ALEXANDR VLADIMIROVICH [RU]

Title: Methods of determining lethality of pathogens and malignancies involving replikin peak genes

Applicant/Assignee:

Application No.: 12/010027   Filing Date: 18/Jan/2008

Abstract:

The present invention provides methods of identifying lethal, virulent and rapidly replicating viruses, organisms, and malignancies comprising comparing Replikin concentrations among different viruses, organisms, or malignancies. The present invention further provides isolated Replikin Peak Genes associated with increased lethality, virulence and rapid replication, for diagnostic, therapeutic and predictive purposes.

Priority: US20070991676P Applic. Date: 2007-11-30; US20070982336P Applic. Date: 2007-10-24; US20070982333P Applic. Date: 2007-10-24; US20070982338P Applic. Date: 2007-10-24; US20070935816P Applic. Date: 2007-08-31; US20070935499P Applic. Date: 2007-08-16; US20070954743P Applic. Date: 2007-08-08; US20070898097P Applic. Date: 2007-01-30; US20070880966P Applic. Date: 2007-01-18

Inventor: BOGOCH SAMUEL [US]; BOGOCH ELENORE S [US]; BOGOCH SAMUEL WINSTON [US]; BORSANYI ANNE ELENORE [US]

Title: COMPOSITIONS FOR REMOVING STAINS FROM DENTAL SURFACES AND METHODS OF MAKING AND USING THE SAME

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 12/239161   Filing Date: 26/Sep/2008

Abstract:

Stain-removing oral compositions, such as gum compositions are herein provided. The compositions include a chelating agent and a surfactant. The surfactant includes a fatty acid salt and at least one component selected from nonionic and anionic surfactants. The fatty acid salt may have at least one hydroxyl functionality. The oral compositions may optionally include an abrasive agent.

Priority: US2004-901872 Applic. Date: 2004-07-29; US2003-719602 Applic. Date: 2003-11-21; US2002-285217 Applic. Date: 2002-10-31

Inventor: HOLME SAMANTHA KATHARINE RACHEAL [US]; LUO SHIUH [US]; GEBRESELASSIE PETROS [US]; BOGHANI NAVROZ [US]

Title: Dental Handpiece

Applicant/Assignee: AMDENT AB

Application No.: 11/795418   Filing Date: 06/Feb/2006

Abstract:

The present invention relates to a dental handpiece (1

1') which comprises a body (3) intended to be held by an operator, such as a dentist or dental hygienist, an implement (9) being able to be fitted in a front part of the body (3) so that the operator is able to carry out an oral procedure on a patient with the aid of the implement (9) when holding the body, a light source (29) being disposed in the body (3) and intended to emit light for illuminating the patient's oral cavity during the oral procedure. The invention is characterized in that the dental handpiece (1

1') additionally comprises a lens arrangement (33) designed to diffuse the light from the light source (29) within the patient's oral cavity.

Priority: SE20050000281 Applic. Date: 2005-02-07; US20050593695P Applic. Date: 2005-02-07; WO2006SE50004 Applic. Date: 2006-02-06

Inventor: ANDERSSON GORAN [SE]

Title: Method of Preparing an Artificial Dental Prosthetic and Seating Thereof

Applicant/Assignee:

Application No.: 12/237133   Filing Date: 24/Sep/2008

Abstract:

An artificial dental prosthetic constructed of a curable resinous dental composition, and a method for preparing and seating the artificial dental prosthetic onto at least one implant in a patient's mouth. The method of preparing the artificial dental prosthetic and seating thereof may be applied to any situation in which one or more artificial dental prosthetic is required, such as a fixed, full artificial dental prosthetic for replacement of a patient's upper and/or lower arches or a fixed, partial artificial dental prosthetic for replacement of a patient's upper and/or lower teeth.

Priority: US2007-734138 Applic. Date: 2007-04-11; US20060863232P Applic. Date: 2006-10-27

Inventor: LETCHER WILLIAM F [US]

Title: DROPLET JET SYSTEM FOR CLEANSING

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 11/814060   Filing Date: 20/Jan/2005

Abstract:

The system includes a reservoir for fluid

a droplet generator for creating a stream of fluid droplets from the fluid wherein the velocity of the stream of droplets is within a range of 20 meters per second to 200 meters per second and the size of the droplets is within a range of 5 microns to 200 microns. A nozzle or nozzles direct the stream of droplets to safely clean a selected tooth or teeth surface area. The specific momentum of effective fluid droplets within the stream of fluid droplets is important in safe and effective cleaning.

Priority: US20040537690P Applic. Date: 2004-01-20; WO2005IB50244 Applic. Date: 2005-01-20

Inventor: GOTTENBOS BART [NL]; JANSSEN JOZEF JOHANNES MARIA [NL]; DE JAGER MARINUS KAREL JOHANNES [NL]; CENSE ADRIAAN WILLEM [NL]; DUINEVELD PAULUS CORNELIS [NL]; HAYENGA JON W [US]; BRYANT WILLIAM E [US]; DEKKER MARTIJN JEROEN [NL]

Title: PROCESS FOR PRODUCING A MULTI-PHASE DETERGENT TABLET

Applicant/Assignee: RECKITT BENCKISER N.V

Application No.: 11/570552   Filing Date: 20/Jun/2005

Abstract:

A process for the manufacture of a detergent tablet comprises filling a recess in a first pre-formed body with a gel

adding a second body to the gel

and allowing/causing the gel to solidify.

Priority: GB20040013800 Applic. Date: 2004-06-19; WO2005GB02405 Applic. Date: 2005-06-20

Inventor: WIEDEMANN RALF [DE]

Title: CAPPED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 12/171814   Filing Date: 11/Jul/2008

Abstract:

The present invention relates to compounds represented by formula (I): where the structural variables are as defined herein. The compounds are useful for promoting hydration of mucosal surfaces.

Priority: US2005-211707 Applic. Date: 2005-08-26; US2004-920410 Applic. Date: 2004-08-18; US20030495725P Applic. Date: 2003-08-18

Inventor: JOHNSON MICHAEL R [US]; MOLINO BRUCE [US]; ZHANG JIANZHONG [US]; SARGENT BRUCE [US]

Title: Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states

Applicant/Assignee:

Application No.: 12/229340   Filing Date: 22/Aug/2008

Abstract:

The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor/anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, including angiogenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.

Priority: US2005-074545 Applic. Date: 2005-03-08; US2002-198786 Applic. Date: 2002-07-18; US2000-748599 Applic. Date: 2000-12-26; US19990171883P Applic. Date: 1999-12-23

Inventor: BOWEN J PHILLIP [US]; ROBINSON THOMAS PHILIP [US]; EHLERS TEDMAN [US]; GOLDSMITH DAVID [US]; ARBISER JACK [US]

Title: Taste sampling process and product

Applicant/Assignee: FIRST FLAVOR, INC

Application No.: 12/217533   Filing Date: 07/Jul/2008

Abstract:

A method for marketing a target product having a flavor to a consumer. A consumable film that is distinct from the target product is provided to the consumer using at least one of the following channels: a print advertisement of the target product, a direct mail advertisement of the target product, a print media insert advertising the target product, a dispenser located at a point-of-purchase of the consumer, a display located at the point-of-purchase of the consumer, a coupon for the target product, a channel for test marketing the target product, an advertisement of the target product contained within a package that includes a product different from the product, or an advertisement of the target product attached to the exterior of a package that contains a different product. The consumable film contains at least one water soluble polymer. The consumable film adheres and dissolves in the mouth of the consumer and thereby renders a likeness of the flavor of the target product to the consumer.

Priority: US2005-054668 Applic. Date: 2005-02-09

Inventor: AZIZ ADNAN A [US]; KOPELMAN JOSHUA M [US]; MINKOFF JAY B [US]

Title: Apparatus and method for holding and manipulating dental floss

Applicant/Assignee:

Application No.: 11/879672   Filing Date: 18/Jul/2007

Abstract:

An apparatus and method are disclosed for firmly and comfortably holding and manipulating dental floss without obstructing blood flow in the fingers. The apparatus provides a high degree of dexterity and tactile control, thereby allowing the dental floss to be easily positioned anywhere within the mouth, and allowing the positioning to be readily guided by touch. The apparatus includes a pair of elastomeric sleeves, each worn on a user's finger. A length of dental floss is tensioned between the sleeves by wrapping each end of the dental floss around a sleeve (each end also preferably being glued to a sleeve) and then separating the sleeves until the floss is pulled tightly between them. The sleeves are then inserted into the mouth so as to pass the floss between the teeth. In preferred embodiments, texturing is provided on each sleeve to inhibit slippage of the dental floss on the sleeve.

Priority:

Inventor: TOMSIC COREY [US]; TOMSIC TAMMY [US]

Title: Packaged dental composition

Applicant/Assignee:

Application No.: 12/284072   Filing Date: 18/Sep/2008

Abstract:

The invention provides a container enclosing an applicator and a dental composition including a volatile organic solvent. The container is sealed. The volatile organic solvent is effectively retained within the container, even after storage at about 43 DEG C. for one week. Preferably the container is made of a copolymer of a cycloolefin and an open chain olefin.

Priority: US20020319581P Applic. Date: 2002-09-27; US2003-668946 Applic. Date: 2003-09-23; US2005-146975 Applic. Date: 2005-06-07; US2006-586798 Applic. Date: 2006-10-26

Inventor: PIERSON PAUL R [US]; HAMMESFAHR PAUL D [US]

Title: Capsule For An Item

Applicant/Assignee:

Application No.: 11/779922   Filing Date: 19/Jul/2007

Abstract:

This invention relates generally to capsules for containers, and more particularly to capsules for housing items with beverage containers, such as wine bottles, champagne bottles, beer bottles, liquor bottles, soda bottles, and the like.

Priority:

Inventor: JOUBERT BRAD T [US]; MITTS JONATHAN P [US]

Title: FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION

Applicant/Assignee: THE UNIVERSITY OF MELBOURNE

Application No.: 12/162683   Filing Date: 09/Feb/2007

Abstract:

The present invention relates to compositions and methods for mineralizing a dental surface or subsurface including providing a composition including stabilized ACP and a source of fluoride ions.

Priority: AU20060900634 Applic. Date: 2006-02-09; AU20060903531 Applic. Date: 2006-06-30; WO2007AU00141 Applic. Date: 2007-02-09

Inventor: REYNOLDS ERIC CHARLES [AU]

Title: Composition and packaging method for animal dental care

Applicant/Assignee:

Application No.: 12/218106   Filing Date: 11/Jul/2008

Abstract:

A comestible, water-based composition containing natural ingredients provides an effective amount of at least one active ingredient selected to reduce the proliferation of bacteria in the mouth of animals to treat and improve the dental health of animals. The composition can be administered to animals in the form of their daily intake of water and may be especially packaged for ready use and consumption by animals in pre-packaged and portable doses. Compositions containing natural ingredients and formulated as toothpastes for animal dental care are also provided.

Priority: US20070959101P Applic. Date: 2007-07-11

Inventor: ALBERT KAREN L [US]

Title: siRNA MICROBICIDES FOR PREVENTING AND TREATING DISEASES

Applicant/Assignee: IMMUNE DISEASE INSTITUTE, INC PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Application No.: 11/916334   Filing Date: 05/Jun/2006

Abstract:

The invention provides a microbicidal composition comprising at least one siRNA. The siRNA is an RNA duplex made of one or two molecules. A portion of the siRNA is identical to a target sequence in an essential gene of a virus. The virus may be a herpesvirus, for example, HSV-1 or HSV-2. Preferably, the herpesvirus is HSV-2. The microbicidal composition further comprises a pharmaceutically acceptable carrier. Also included in the invention are methods to prevent and treat viral infections by administration of the microbicidal composition. Preferably, the microbicidal composition is administered transmucosally.

Priority: US20050687216P Applic. Date: 2005-06-03; WO2006US21758 Applic. Date: 2006-06-05

Inventor: LIEBERMAN JUDY [US]; PALLISER DEBORAH [US]; KNIPE DAVID [US]

Title: COMPOSITIONS THAT CONTAIN BETA-GLUCAN TO BE USED FOR THE PREVENTION AND TREATMENT OF DISEASE AND METHODS FOR THEIR USE

Applicant/Assignee:

Application No.: 11/867309   Filing Date: 04/Oct/2007

Abstract:

This application for patent discloses beta-Glucan containing compositions, dosage forms, delivery methods, and techniques for the purposes of preventing and treating mucositis through wound healing and tissue re-organization, as well as the treatment of immune disorders such as Alzheimer's disease, Multiple Sclerosis and Parkinson's disease. beta-Glucan containing compositions, dosage forms and methods to deliver therapeutic and prophylactic vaccines and anti-cancer drugs are also disclosed, as are methods to stabilize a drug to enhance its shelf life and to enhance the level and duration of its bioactivity.

Priority: US20060850284P Applic. Date: 2006-10-06

Inventor: BARMAN SHIKHA PRAMANIK [US]

Title: Tooth preparation solution and method

Applicant/Assignee:

Application No.: 11/879437   Filing Date: 17/Jul/2007

Abstract:

A method of preparing teeth for the adhesion of a component includes applying to at least one tooth a solution of liquid phosphoric acid and an abrasive such as pumice, removing the solution, and applying an adhesive for placing a component on the teeth.

Priority:

Inventor: BESSON FRANK R [US]

Title: Dental glass ceramics

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 11/921816   Filing Date: 31/May/2006

Abstract:

The invention relates to dental glass-ceramics and a process for producing them and their use, with these comprising at least one crystal phase containing xenotime or monazite or mixtures thereof.

Priority: DE200510026269 Applic. Date: 2005-06-08; WO2006EP62761 Applic. Date: 2006-05-31

Inventor: HOLAND WOLFRAM [LI]; RITZBERGER CHRISTIAN [AT]; RHEINBERGER VOLKER [LI]; APEL ELKE [CH]

Title: Method for the surface treatment of bead polymers

Applicant/Assignee: BAUER TECHNOLOGIES GMBH

Application No.: 11/911307   Filing Date: 12/Apr/2006

Abstract:

A method for the surface treatment of bead polymers is to be prepared, by means of which bead polymers are treated in a particularly simple and effective manner such that upon addition to unfinished ceramic pieces, in particular, their strength and dimensional stability increase. To this end, the bead polymers are conducted to a device which is used for comminution, in particular, to a mill, in which the surface of the bead polymers is purposefully scratched or roughened in a uniformly mechanical manner.

Priority: DE200510017586 Applic. Date: 2005-04-16; WO2006EP03372 Applic. Date: 2006-04-12

Inventor: KRYTS OTTMAR [DE]

Title: Heteroaryl compounds, compositions thereof, and methods of treatment therewith

Applicant/Assignee:

Application No.: 11/975652   Filing Date: 18/Oct/2007

Abstract:

Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.

Priority: US20060853166P Applic. Date: 2006-10-19

Inventor: MORTENSEN DEBORAH SUE [US]; DELGADO MEDEROS MARIA MERCEDES [US]; SAPIENZA JOHN JOSEPH [US]; ALBERS RONALD J [US]; LEE BRANDEN G [US]; HARRIS III ROY LEONARD [US]; SHEVLIN GRAZIELLA ISABEL [US]; HUANG DEHUA [US]; SCHWARZ KIMBERLY LYN [US]; PACKARD GARRICK K [US]; PARNES JASON SIMON [US]; PAPA PATRICK WILLIAM [US]; TEHRANI LIDA RADNIA [US]; PERRIN-NINKOVIC SOPHIE [US]; RIGGS JENNIFER R [US]

Title: Novel substituted heteroaryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee:

Application No.: 11/658892   Filing Date: 24/Aug/2005

Abstract:

This invention relates to novel substituted heteroaryloxy alkylamines useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20040001291 Applic. Date: 2004-08-26; US20040605174P Applic. Date: 2004-08-30; WO2005EP54152 Applic. Date: 2005-08-24

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JORGEN [DK]; OLSEN GUNNAR M [DK]

Title: Diphenyl Urea Derivatives

Applicant/Assignee: ARPIDA AG

Application No.: 12/097191   Filing Date: 08/Dec/2006

Abstract:

The invention relates to novel specifically trifluoromethyl and halogen substituted 1,3-diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects like the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as anti-infectives.

Priority: WO2005EP13345 Applic. Date: 2005-12-13; WO2006EP11794 Applic. Date: 2006-12-08

Inventor: LOEWE RALF [CH]; LOCIURO SERGIO [CH]; HAWSER STEPHEN [FR]; SCHMITT LAURENT [FR]

Title: Time-Indicating Syringe Mixing Devices And Related Methods For Storing and Dispensing Two-Part Dental Compositions

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 12/242555   Filing Date: 30/Sep/2008

Abstract:

Time-indicating syringe mixing systems for mixing, storing, and dispensing a two-part dental composition that becomes less stable upon mixing including a first plunger comprising an elongate stem and a plug at a distal end of the elongate stem, a hollow first chamber configured to contain a first component, a hollow second chamber configured to contain a second component, and means for indicating a recorded date when a first component initially contained within the hollow first chamber is mixed with a second component initially contained within the hollow second chamber. The inventive syringe mixing systems may be configured as syringe-in-syringe systems and/or syringe-to-syringe systems.

Priority: US2007-736457 Applic. Date: 2007-04-17; US2006-414964 Applic. Date: 2006-05-01; US2006-537883 Applic. Date: 2006-10-02; US2007-673334 Applic. Date: 2007-02-09

Inventor: MCLEAN BRUCE S [US]; FISCHER DAN E [US]; JESSOP NEIL [US]

Title: Tobacco-free oral flavor delivery pouch product

Applicant/Assignee: PHILIP MORRIS USA INC

Application No.: 12/219118   Filing Date: 16/Jul/2008

Abstract:

Provided is a tobacco-free oral flavor delivery pouch product that provides and engaging and flavorful experience to a user. The pouch product includes a porous pouch wrapper and an inner filling material. The inner filling material can include a non-tobacco, botanical component, at least one functional ingredient and a solid flavor component dispersed throughout the inner filling material. The pouch product delivers multiple textures to the user's mouth.

Priority: US20070929875P Applic. Date: 2007-07-16

Inventor: CRAWFORD DANIELLE R [US]; BROOKS KAREN [US]; NEWMAN KENNETH A [US]; SWEENEY WILLIAM R [US]; CHAPPELL SR FERNANDO L [US]

Title: MEDICAL AND DENTAL TOOL CLEANING DEVICE

Applicant/Assignee:

Application No.: 11/782256   Filing Date: 24/Jul/2007

Abstract:

An apparatus for cleaning of dental instruments and medical instruments. The apparatus includes a body for holding such instruments that is biased apart from an immersion tank. The retained instruments can be lowered into the immersion tank by hand operation. After the hand pressure is removed, the instruments are biased to pull out of the immersion bath. The instruments are then blown dry by pressurized gas.

Priority:

Inventor: CIAMPAGLIA OSCAR [US]

Title: SPREADABLE FLUID MATERIAL DISPENSER APPARATUS

Applicant/Assignee: INNOVATIVE CONSUMER SOLUTIONS, LLC

Application No.: 12/182259   Filing Date: 30/Jul/2008

Abstract:

A dispenser for fluid material that facilitates spreading of the fluid material is disclosed. The dispenser can comprise a unitary construction, or can be composed of a plurality of components that can be fastened together. Disposable cartridges containing fluid material can be attached to the dispenser, and the material within can be dispensed on a surface. The dispenser provides metered dispensing.

Priority: US2007-847257 Applic. Date: 2007-08-29; US20060823855P Applic. Date: 2006-08-29; US20060823857P Applic. Date: 2006-08-29; US20060823860P Applic. Date: 2006-08-29; US20060823864P Applic. Date: 2006-08-29; US20060823866P Applic. Date: 2006-08-29; US20060823869P Applic. Date: 2006-08-29

Inventor: DEVIRAG FRANCIS KISS [US]; ROSNER ILEEN [US]; ROSNER JONATHAN [US]

Title: INHIBITORS OF AKT/PKB WITH ANTI-TUMOR ACTIVITY

Applicant/Assignee: UNIVERSITY OF SOUTH FLORIDA

Application No.: 12/172831   Filing Date: 14/Jul/2008

Abstract:

The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of Akt proteins. The subject invention also concerns methods for inhibiting or killing a cancer cell or other cell in which expression of an Akt protein is elevated or constitutively active, comprising contacting the cell with an effective amount of a compound of formula I. The subject invention also concerns methods for treating cancer or a tumor in a person or animal comprising administering all effective amount of a compound of formula I to the person or animal.

Priority: US20070949365P Applic. Date: 2007-07-12

Inventor: CHENG JIN Q [US]; SUN MEI [US]; SEBTI SAID M [US]

Title: Carrier conjugates of gnrh-peptides

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 11/659221   Filing Date: 04/Aug/2005

Abstract:

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising a virus like particle (VLP) and at least one GnRH peptide or fragment or variant thereof linked thereto. The invention also provides a process for producing the composition. The compositions of the invention are useful in the production of vaccines for the treatment of GnRH-related diseases and conditions and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.

Priority: US20040598581P Applic. Date: 2004-08-04; US20050673396P Applic. Date: 2005-04-21; WO2005EP53858 Applic. Date: 2005-08-04

Inventor: BACHMANN MARTIN F [CH]; FULURIJA ALMA [CH]; JENNINGS GARY [CH]; MEIJERINK EDWIN [NZ]

Title: USE OF A POLYSACCHARIDE WHICH IS EXCRETED BY THE VIBRIO DIABOLICUS SPECIES FOR THE REGENERATION AND PROTECTION OF THE PERIODONTIUM

Applicant/Assignee: UNIVERSITE RENE DESCARTES PARIS 5

Application No.: 12/096588   Filing Date: 06/Dec/2007

Abstract:

The invention relates to the use of a polysaccharide which is excreted by the Vibrio diabolicus species for the re-generation and protection of the non-mineralised connective tissue of the periodontium.

Priority: FR20050012415 Applic. Date: 2005-12-07; WO2006FR02667 Applic. Date: 2006-12-06

Inventor: SENNI KARIM [FR]; SINQUIN CORINNE [FR]; COLLIEC-JOUAULT SYLVIA [FR]; GODEAU GASTON-JACQUES [FR]; GUEZENNEC JEAN [FR]

Title: METHOD AND APPARATUS FOR WHITENING TEETH

Applicant/Assignee: SMILE STUDIO (UK) LIMITED

Application No.: 12/161840   Filing Date: 24/Jan/2006

Abstract:

An apparatus (1) for use in whitening teeth comprises support means (7) for being worn on a person's body, a source of radiant heat (9) and position adjusting means (5) connected to said source (9) and said support means (7) for enabling the source (9) to be adjusted to and held in a position adjacent to the person's teeth.

Priority: WO2006GB00239 Applic. Date: 2006-01-24

Inventor: CHAN WYMAN [GB]

Title: METHOD FOR MANUFACTURING DENTAL IMPLANT AND DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179628   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a titanium molded body production step for molding a titanium molded body composition to obtain a titanium molded body, an assembling step for assembling the titanium molded body and a ceramic member together to obtain an assembled body, a degreasing step for degreasing the assembled body so that the titanium molded body is transformed into a titanium degreased body, and a sintering step for sintering the assembled body to transform the titanium degreased body into a titanium member so that the titanium member is firmly fixed to the ceramic member.

Priority: JP20070196495 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]

Title: METHOD FOR MANUFACTURING DENTAL IMPLANT AND DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179842   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a titanium molded body production step for molding a titanium molded body composition to obtain a titanium molded body, a ceramic molded body production step for molding a ceramic molded body composition to obtain a ceramic molded body, an assembling step for assembling the titanium molded body and the ceramic molded body together to obtain an assembled body, a degreasing step for degreasing the assembled body so that the titanium molded body is transformed into a titanium degreased body and the ceramic molded body is transformed into a ceramic degreased body, and a sintering step for sintering the assembled body to transform the titanium degreased body into a titanium member as a sintered body and to transform the ceramic degreased body into a ceramic member as a sintered body so that the titanium member and the ceramic member are firmly fixed and joined together.

Priority: JP20070196497 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]

Title: DENTAL IMPLANT AND METHOD FOR MANUFACTURING DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179913   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a titanium molded body production step for molding a titanium molded body composition to obtain a titanium molded body having one of male and female thread portions, a ceramic molded body production step for molding a ceramic molded body composition to obtain a ceramic molded body having the other thread portion which makes thread coupling with the one thread portion, an assembling step for assembling the titanium molded body and the ceramic molded body together so that the one thread portion makes thread coupling with the other thread portion, to obtain an assembled body, a degreasing step for degreasing the assembled body, and a sintering step for sintering the assembled body thus degreased.

Priority: JP20070196498 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]

Title: METHOD FOR MAUFACTURING DENTAL IMPLANT AND DENTAL IMPLANT

Applicant/Assignee: SEIKO EPSON CORPORATION

Application No.: 12/179636   Filing Date: 25/Jul/2008

Abstract:

A dental implant capable of reliably preventing elution of metal when the dental implant is applied within an oral cavity and capable of reliably preventing occurrence of mismatching (bumpy occlusion or the like) when the dental implant is fixed in place, and a method for manufacturing the dental implant are provided. In the method for manufacturing a dental implant including an abutment, the abutment is manufactured through the steps including a ceramic molded body production step for molding a ceramic molded body composition to obtain a ceramic molded body, an assembling step for assembling a titanium member and the ceramic molded body together to obtain an assembled body, a degreasing step for degreasing the assembled body so that the ceramic molded body is transformed into a ceramic degreased body, and a sintering step for sintering the assembled body to transform the ceramic degreased body into a ceramic member so that the ceramic member is firmly fixed to the titanium member.

Priority: JP20070196496 Applic. Date: 2007-07-27

Inventor: HAYASHI JUNICHI [JP]; ITO MICHIO [JP]

Title: Use of Stem Cells, Method of Tissue Engineering, Use of Dental Tissues and Tooth Biological Substitute

Applicant/Assignee: MASSACHUSETTS GENERAL HOSPITAL

Application No.: 11/630476   Filing Date: 23/Jun/2005

Abstract:

The present invention is related to the use of stem cells of an animal species for obtainment of biological tooth substitute, in whole or in parts, to be implanted in organism of the same animal strain, wherein said stem cells can be adult cells. The present invention still aims to develop a method of tissue engineering for culturing cells capable to form dental tissue for production of a tooth biological substitute. The said dental tissue can used for the treatment of people suffering from loss, fail or lack of these tissues, and also for cosmetic use of those tissues for a morphological modifying on a patient dentition, for example, the patient may desire to, or need to, have a bigger or smaller dentition for any aesthetic reason.

Priority: BR2004PI02659 Applic. Date: 2004-06-23; WO2005BR00121 Applic. Date: 2005-06-23

Inventor: DUAILIBI SILVIO EDUARDO [BR]; DUAILIBI MONICA TALARICO [BR]; YELICK PAMELA C [US]; VACANTI JOSEPH P [US]

Title: SUBSTITUTED PYRAZOLE COMPOUNDS

Applicant/Assignee:

Application No.: 12/137355   Filing Date: 11/Jun/2008

Abstract:

Disclosed are protein kinase inhibitors, compositions comprising such inhibitors, and methods of use thereof. More particularly, disclosed are inhibitors of Aurora A (Aurora-2) protein kinase. Also disclosed are methods of treating diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer.

Priority: US20070934062P Applic. Date: 2007-06-11; US20070990475P Applic. Date: 2007-11-27

Inventor: AGOSTON GREGORY E [US]; TRESTON ANTHONY M [US]; LADOUCEUR GAETAN [US]; SUWANDI LITA [US]

Title: 3-Aryloxy-8-aza-bicyclo[3.2.1]]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/921844   Filing Date: 07/Jun/2006

Abstract:

This invention relates to novel 8-aza-bicyclo[3.2.1]oct-6-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000839 Applic. Date: 2005-06-08; WO2006EP62952 Applic. Date: 2006-06-07

Inventor: PETERS DAN [DK]; BROWN DAVID TRISTRAM [DK]; REDROBE JOHN PAUL [DK]; NIELSEN ELSEBET OSTERGAARD [DK]

Title: Dental cement composition containing composite particles with grafted polyacidic polymer chains

Applicant/Assignee: DENTSPLY DE TREY GMBH

Application No.: 12/284275   Filing Date: 19/Sep/2008

Abstract:

A dental cement composition comprising (i) a particulate reactive inorganic filler capable of leaching metal ions in the presence of an acid, and (ii) composite particles with grafted polyacidic polymer chains, which are obtainable by a process comprising the following steps: (a) polymerizing one or more free radically polymerizable monomers containing optionally protected acidic groups in the presence of (a1) an initiatior system comprising initiator particles displaying a moiety comprising a radically transferable atom or group as a polymerization initiation site

and (a2) a catalyst facilitating controlledliving polymerisation, and (a3) optionally further polymerizable monomers, for forming a composite particle with grafted optionally protected polyacidic polymer chains

and (b) optionally deprotecting protected acidic groups, for forming composite particles with grafted polyacidic polymer chains.

Priority: EP20040012495 Applic. Date: 2004-05-26; US2005-217542 Applic. Date: 2005-09-01; US20040606114P Applic. Date: 2004-09-01

Inventor: KLEE JOACHIM E [DE]; BRUGGER STEFAN [DE]; WEBER CHRISTOPH [DE]; MULLER AXEL H E [DE]; MORI HIDEHARU [JP]

Title: Porous plastic smokeless tobacco substitutes

Applicant/Assignee:

Application No.: 12/079964   Filing Date: 31/Mar/2008

Abstract:

Systems and methods for providing synthetic substitutes for smokeless tobacco are provided. In one form, the application relates to systems for cessation of smokeless tobacco use and methods for making and using same. More particularly, but not exclusively, the application relates to the use of a plurality of porous plastic dispensing members sized and structured to imitate a quantity of smokeless tobacco, such as chewing tobacco. The porous plastic members define a matrix including an internal network of passages in communication with pores on the exterior of the dispensing members. Residing within the matrix is a dispensate imitative of one or more characteristics of smokeless tobacco which is extractable from the matrix upon exposure to a fluid. In one form, the dispensate may be a tobacco derivative including one or more of nicotine, tobacco flavoring, menthol, vitamins, minerals, therapeutic agents, and/or additional flavoring.

Priority: US20070920947P Applic. Date: 2007-03-30

Inventor: LUZENBERG JR ROBERT S [US]

Title: Low Friction Coatings for Use in Dental and Medical Devices

Applicant/Assignee: YEDA RESEARCH AND DEVELOPMENT COMPANY LTD HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LT HOLON ACADEMIC INSTITUTE OF TECHNOLOGY

Application No.: 11/920356   Filing Date: 17/May/2006

Abstract:

The present invention provides an article, at least part of it being coated by inorganic fullerene-like (IF) nanoparticles or composite containing such nanoparticles. Preferably, the invention provides an article made of metal, for use in dentistry or medicine e.g. archwire, needle or catheter, having a friction-reducing film, and methods for coating such articles with a friction-reducing film.

Priority: US20050681443P Applic. Date: 2005-05-17; WO2006IL00578 Applic. Date: 2006-05-17

Inventor: TENNE RESHEF [IL]; KATZ ALON [IL]; REDLICH MEIR [IL]; RAPOPORT LEV [IL]

Title: HARDENABLE SELF-SUPPORTING STRUCTURES AND METHODS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/250309   Filing Date: 13/Oct/2008

Abstract:

Compositions, particularly for forming dental products, having a hardenable self-supporting structure with sufficient malleability to be subsequently customized into a second shape and then hardened, and methods.

Priority: US2002-219398 Applic. Date: 2002-08-15; US20010312355P Applic. Date: 2001-08-15

Inventor: KARIM NAIMUL [US]; JONES TODD D [US]; LEWANDOWSKI KEVIN M [US]; FANSLER DUANE D [US]; NELSON JAMES M [US]; SALVIEJO-RIVAS MARCELINO [US]; GADDAM BABU N [US]; ABUELYAMAN AHMED S [US]; MITRA SUMITA B [US]

Title: IMAGE SENSOR WITH CORNER CUTS

Applicant/Assignee: E2V

Application No.: 11/994403   Filing Date: 15/Jun/2006

Abstract:

The invention relates to image sensors using a chip with cut corners. The sensor comprises a chip with cut corners comprising a matrix (10) of horizontal lines and vertical columns of photosensitive members, the matrix having a generally rectangular shape of horizontal width W and having four bevels, the sensor comprising as many current or voltage read blocks as there are matrix columns, in order to read the image signals detected by the photosensitive members, characterized in that the current or voltage read blocks are placed in a row (30, 30') along a horizontal edge of the matrix of width W' and are all housed within a vertical strip, the width W1 of which is substantially less than the maximum width W of the matrix. There are two superposed rows of current read blocks with blocks distributed at the same pitch as the pixel columns, or there is a single row with read blocks distributed with a pitch less than that of the pixel columns. The invention can be applied to CMOS technology intraoral radiological sensors.

Priority: FR20050007035 Applic. Date: 2005-07-01; WO2006EP63251 Applic. Date: 2006-06-15

Inventor: LIGOZAT THIERRY [FR]; CHENEBAUX GREGOIRE [FR]

Title: USE OF CRANBERRY EXTRACT ENRICHED IN TOTAL PHENOLS AND FREE, ESSENTIALLY FREE, OR SUBSTANTIALLY FREE OF SUGARS, ACIDS, SULFUR AND OTHER CONTAMINANTS, FOR PERIODONTAL TREATMENT

Applicant/Assignee: PHENOLICS, LLC

Application No.: 12/183943   Filing Date: 31/Jul/2008

Abstract:

Cranberry and other plant extracts enriched in total phenols and free or substantially free of sugars, acids, sulfur and other contaminants are used for periodontal treatments. The periodontal treatments of the present invention include swish and swallow techniques, in which the extracts enriched in total phenols but free or substantially free of sugars, acids, sulfur and other contaminants, are solubilized in water or other solvent, placed in the mouth, swished around the teeth and then swallowed. Other application techniques include gel applications, gum formulations and toothpaste formulations.

Priority: US20070953143P Applic. Date: 2007-07-31

Inventor: TEMPESTA MICHAEL S [US]; DAUGHERTY F JOSEPH [US]

Title: SKIN AND SURFACE DISINFECTANT COMPOSITIONS CONTAINING BOTANICALS

Applicant/Assignee:

Application No.: 12/016788   Filing Date: 18/Jan/2008

Abstract:

The present invention relates to a skin or surface disinfectant composition with broad spectrum antimicrobial activity comprising one or more essential oil (and/or one or more component thereof) and one or more fruit acid. The compositions of the invention may be used as non-toxic alternatives to conventional disinfectants or may be added to other antimicrobial agents to enhance their activity. The invention provides effective alternatives to harsher products which may be particularly useful in personal care and household products and where children and/or pet exposure may be a concern.

Priority: US20070953654P Applic. Date: 2007-08-02

Inventor: MODAK SHANTA [US]; BAIJU NAYANA [US]; CARAOS LAUSERPINA [US]

Title: PHARMACEUTICAL COMPOSITION FOR IMPROVING ORAL HYGIENE AND METHODS THEREOF

Applicant/Assignee:

Application No.: 11/833530   Filing Date: 03/Aug/2007

Abstract:

An aqueous based pharmaceutical composition for use as a oral hygienic treatment is described. The composition contains a pharmaceutically effective amount of a tetracycline-based antibiotic

a water-soluble calcium salt that aids in solubilizing the tetracycline-based antibiotic

a thickener

a pH adjustment agent

an antifoaming agent

an excipient

a surfactant

a preservative

and a flavoring agent. A method of making the aqueous based pharmaceutical composition includes the steps of adjusting, defoaming, dispensing, dispersing, dissolving, flavoring, heating, minimizing, pouring, solubilizing, suspending, and sweetening. A method of using the aqueous based pharmaceutical composition is also disclosed which includes the steps of expectorating, gargling, obtaining, pouring, receiving, and swishing.

Priority:

Inventor: EIREW GARY H [US]

Title: METHOD OF APPLYING AN INJECTABLE FILLER

Applicant/Assignee:

Application No.: 12/184966   Filing Date: 01/Aug/2008

Abstract:

Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an elevated level of effectiveness of the injectable filler. In some embodiments, the methods can prolong the effectiveness of the injectable filler.

Priority: US20070953661P Applic. Date: 2007-08-02

Inventor: WORTZMAN MITCHELL S [US]; NARINS RHODA [US]; LIN XIAOMING [US]

Title: Pluripotent embryonic-like stem cells derived from teeth and uses thereof

Applicant/Assignee: STIFTUNG CAESAR

Application No.: 12/068695   Filing Date: 11/Feb/2008

Abstract:

A stem cell which is obtainable from the non-embryonic tissue isolated from the dental follicle of tooth or wisdom tooth which are able to differentiate into a periodontal ligament like membrane structure.

Priority: US2005-497206 Applic. Date: 2005-01-10; WO2003EP01131 Applic. Date: 2003-02-05; US20020354152P Applic. Date: 2002-02-06

Inventor: SCHIERHOLZ JORG [DE]; ZEILHOFER HANS-FLORIAN [CH]; HOFFMANN KARL-HEINZ [DE]; MORSCZECK CHRISTIAN [DE]; BRENNER NORBERT [DE]

Title: COATING MATERIAL

Applicant/Assignee:

Application No.: 10/580300   Filing Date: 17/Nov/2004

Abstract:

The invention relates to an antimicrobial and preferably non-cytotoxic coating material and to use of said coating material.

Priority: DE20031053756 Applic. Date: 2003-11-17; WO2004EP13030 Applic. Date: 2004-11-17

Inventor: WAGENER MICHAEL [DE]; VISSING KLAUS DIETER [DE]; SALZ DIRK [DE]; STEINRUCKE PETER [DE]

Title: Stem cells obtained from pulp of deciduous or permanent teeth and of dental germ, able to produce human bone tissue

Applicant/Assignee:

Application No.: 11/658524   Filing Date: 27/Jul/2005

Abstract:

In this invention is described a method that foresees the isolation of a new subpopulation of stem cells derived form dental pulp, whose differentiation is osteoblasts lead to the subsequent production and employment of a bone tissue, called LAB (Living Autologous Bone). Specifically, the invention describes: 1) the isolation of stem cells from the pulp of deciduous and permanent teeth and of dental germs, obtained from human subjects

2) the growth of these cells in vitro, under specific conditions that allow the isolation of a cellular sub-population, which, after differentiation in osteoblasts, is able to produce in vitro an extracellular matrix, identical to that detectable in bone tissue

3) the use of this selected and differentiated cell population in order to produce autologous bone tissue in vitro, containing vital osteoblasts

4) the preservation of the LAB under conditions which guarantee cellular vitality

5) the use of the LAB in donor patients to reconstruct bone tissue, as required in the daily practice in dentistry, maxillo-facial surgery and orthopedics.

Priority: IT2004NA00043 Applic. Date: 2004-07-28; WO2005EP08136 Applic. Date: 2005-07-27

Inventor: CARINCI FRANCESCO [IT]; D AQUINO RICCARDO [IT]; DE ROSA ALFREDO [IT]; GRAZIANO ANTONIO [IT]; LAINO GREGORIO [IT]; PAPACCIO GIANPAOLO [IT]

Title: Methods and systems for concurrent tooth repositioning and substance delivery

Applicant/Assignee:

Application No.: 12/286193   Filing Date: 29/Sep/2008

Abstract:

The present invention provides devices, systems and methods for orthodontic treatment using elastic repositioning appliances while concurrently providing dental and periodontal therapies. Such therapies are traditionally provided with the use of a variety of accessories and devices which are applied when the repositioning appliance is removed from the patient's mouth. The present invention eliminates the need for such removal and additional devices by incorporating these therapies into the repositioning appliance.

Priority: US2007-745211 Applic. Date: 2007-05-07; US2000-666783 Applic. Date: 2000-09-21

Inventor: KUO ERIC [US]; PHAN LOC X [US]

Title: PHOTODISINFECTION OF ORAL CAVITY

Applicant/Assignee: ONDINE INTERNATIONAL, LTD

Application No.: 12/179977   Filing Date: 25/Jul/2008

Abstract:

A composition for photodisinfection of the oral cavity comprising toothpaste and a photosensitizing composition encapsulated within microspheres, wherein the microspheres release the photosensitizing composition into the oral cavity upon contact with liquid and/or force and the photosensitizing composition includes a photosensitizer that upon irradiation of at least one predetermined wavelength will reduce and/or eliminate microbes in the oral cavity. The present invention also includes a method of applying the composition into the oral cavity and applying irradiation to the oral cavity at a wavelength or wavelengths absorbed by the photosensitizing composition so as to reduce or eliminate microbes in the oral cavity.

Priority: US20070953541P Applic. Date: 2007-08-02

Inventor: LOEBEL NICHOLAS G [US]; STREET CALE [US]

Title: Dental Prosthesis

Applicant/Assignee:

Application No.: 11/575918   Filing Date: 08/Jun/2006

Abstract:

The method for producing ceramic coping of the present invention comprises the following steps: (i) covering a tooth model with at least one layer of plastic

(ii) coating a plastic covered tooth model from step (i) with alumina gel and letting it dry to form a ceramic coping in green state

(iii) sintering the ceramic coping in green state from step (ii) at a temperature up to 1200 DEG C.

(iv) coating the ceramic coping from step (iii) with crystal hardening powder

(v) firing the crystal hardening powder coated ceramic coping from step (iv) at a temperature up to 1200 DEG C. for effecting crystal hardening of the ceramic coping. Then, the finished ceramic coping can be coated with an outer aesthetic layer to form a dental prosthesis.

Priority: WO2006IB01509 Applic. Date: 2006-06-08; MY20050003268 Applic. Date: 2005-07-18

Inventor: BOZDEMIR ADNAN [MY]

Title: SELF-ETCHING EMULSION DENTAL COMPOSITIONS AND METHODS

Applicant/Assignee: 3M ESPE AG 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/248338   Filing Date: 09/Oct/2008

Abstract:

The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.

Priority: US2004-916169 Applic. Date: 2004-08-11; US20030494603P Applic. Date: 2003-08-12

Inventor: AASEN STEVEN M [US]; ABUELYAMAN AHMED S [US]; CINADER JR DAVID K [US]; GRUPP HENDRIK M [DE]; HANSEN MIRIAM [DE]; KLETTKE THOMAS [DE]; LECHNER GUENTHER [DE]; LEWANDOWSKI KEVIN M [US]; LUCHTERHANDT THOMAS [DE]; MITRA SUMITA B [US]; RAO PRABHAKARA S [US]; RUSSELL VICTORIA A [US]; WENDLAND MICHAEL S [US]

Title: 3,9-DIAZABICYCLO[3.3.1]NONANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 12/161905   Filing Date: 09/Feb/2007

Abstract:

This invention relates to novel 3,9-diazabicyclo[3.3.1]nonane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20060000189 Applic. Date: 2006-02-10; DK20060000192 Applic. Date: 2006-02-10; US20060771892P Applic. Date: 2006-02-10; US20060771891P Applic. Date: 2006-02-10; WO2007EP51270 Applic. Date: 2007-02-09

Inventor: PETERS DAN [SE]; REDROBE JOHN PAUL [DK]; NIELSEN ELSEBET OSTERGAARD [DK]

Title: ENDOPARASITICIDAL TOPICAL COMPOSITIONS

Applicant/Assignee: WYETH

Application No.: 12/182253   Filing Date: 30/Jul/2008

Abstract:

The present invention provides a composition which comprises: an effective amount of (a) praziquantel and (b) a second endoparasiticidal agent selected from the group consisting of a macrocyclic lactone, imidacloprid and a combination thereof

and (c) 4-allyl-2-methoxyphenol as carrier. Also provided is a method for the treatment of endoparasitic infection and infestation in a homeothermic animal.

Priority: US20070962754P Applic. Date: 2007-07-31

Inventor: FATTOHI NAHLA [US]; LAWRENCE MOSES COLUMBUS [US]; SABNIS SHOBHAN SHASHIKANT [US]

Title: Novel 3-Aza-Spiro[5,5]Undec-8-Ene Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/922929   Filing Date: 28/Jun/2006

Abstract:

This invention relates to novel 3-aza-spiro[5.5]undec-8-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000959 Applic. Date: 2005-06-28; US20050594679P Applic. Date: 2005-04-28; WO2006EP63633 Applic. Date: 2006-06-28

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [SE]; NIELSEN ELSEBET OSTERGAARD [DK]; REDROBE JOHN PAUL [DK]

Title: Skin appearance through gene manipulation

Applicant/Assignee:

Application No.: 12/286033   Filing Date: 26/Sep/2008

Abstract:

The present invention relates to a method for treating, preventing and improving the condition and/or aesthetic appearance of aging skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, through meroterpene induced gene manipulation.

Priority: US2007-803188 Applic. Date: 2007-05-14; US2007-986719 Applic. Date: 2007-11-26

Inventor: CHAUDHURI RATAN K [US]

Title: Dental Composites with a Low Shrinkage Tension and High Flexural Strength

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 12/168512   Filing Date: 07/Jul/2008

Abstract:

Dental composite materials based on (meth)acrylate, exhibiting a proportion of TCD monomers in the total composition of 1-15% by weight and the quotient of flexural strength/shrinkage tension is at least 35.

Priority: DE200710034457 Applic. Date: 2007-07-20

Inventor: UTTERODT ANDREAS [DE]; RUPPERT KLAUS [DE]; SCHAUB MATTHIAS [DE]; DIEFENBACH CHRISTINE [DE]; REISCHL KURT [DE]; HOHMANN ALFRED [DE]; ECK MICHAEL [DE]; SCHONHOF NELLI [DE]; SCHNEIDER JUTTA [DE]

Title: Methods for the directed expansion of epitopes for use as antibody ligands

Applicant/Assignee: PEPTIMMUNE, INC

Application No.: 12/151762   Filing Date: 07/May/2008

Abstract:

The instant invention comprises a process for selecting and manufacturing antibodies useful for therapeutic, prophylactic, diagnostic or research purposes using epitope peptide mixtures synthesized by the solid phase synthesis, such process defined by a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting antibodies are related to but distinct from antibodies that bind to the known epitope.

Priority: US2007-787229 Applic. Date: 2007-04-13; US20070928225P Applic. Date: 2007-05-07; US20070999283P Applic. Date: 2007-10-16; US20070999284P Applic. Date: 2007-10-16; US20080124689P Applic. Date: 2008-04-17; US20060792085P Applic. Date: 2006-04-13

Inventor: BONNIN DUSTAN [US]

Title: FULL FACE RESPIRATORY MASK WITH INTEGRATED NASAL INTERFACE

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 12/256059   Filing Date: 22/Oct/2008

Abstract:

A patient interface that reliably and comfortably seals a user's face by providing an oral-nasal mask that includes an integrated nasal interface. The patient interface includes a seal member having an oral cushion portion configured to surround the user's mouth and a nasal interface portion that provides an interface with the user's nose. The seal member, including the oral cushion portion and the nasal interface portion, is a unitary member. Finally, the nasal interface portion remains below the bridge of the nose.

Priority: US2006-633888 Applic. Date: 2006-12-05; US20050748311P Applic. Date: 2005-12-07

Inventor: HO PETER CHI FAI [US]; EATON JASON P [US]

Title: DISPOSABLE DENTAL APPLIANCE

Applicant/Assignee: ICC INNOVATIVE CONCEPTS CORPORATION

Application No.: 12/170425   Filing Date: 09/Jul/2008

Abstract:

A disposable device for cleaning teeth which incorporates cleaning and/or fluoride components is disclosed. An open compartment defines an elongated volume and an elongated opening extending around the periphery of the top of the volume. A flange is disposed adjacent to the periphery of the top of the volume. The flange is integral with the compartment. This compartment is configured to be substantially flat. A closure member is disposed over the flange. This closure member is secured around the entire periphery of the top of the volume. The closure member may be removed when it is so desired. The compartment can be sealed. The tubular member is contained in the compartment. A quantity of toothpaste is disposed in the compartment.

Priority:

Inventor: CANINO SERAFINO [US]; GELORMINO SCOTT [US]

Title: Baby bottle apparatus with powder charge to make beverage

Applicant/Assignee:

Application No.: 12/214275   Filing Date: 17/Jun/2008

Abstract:

Apparatus for administering a liquid formulation to a baby or child includes a bottle charged with water, a dispensing valve mounted on the bottle, and a dust cover that extends over and protects the dispensing valve. The dust cover is hollow and is charged with powder that is mixed with water in the bottle to produce the liquid formulation.

Priority: US2005-259967 Applic. Date: 2005-10-26; US2004-998480 Applic. Date: 2004-11-29; US20050673746P Applic. Date: 2005-04-21; US20070934992P Applic. Date: 2007-06-18; US20080072314P Applic. Date: 2008-03-28

Inventor: REA DONALD J [US]; BARGMAN RONALD D [US]

Title: Wax Foamable Vehicle and Pharmaceutical Compositions Thereof

Applicant/Assignee: FOAMIX LTD

Application No.: 12/187840   Filing Date: 07/Aug/2008

Abstract:

Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided. In some embodiments, the wax is a liquid wax. In some embodiments, the wax includes a solid wax and a liquid wax. The compositions are substantially free of crystals. The components are selected to provide a composition that is substantially resistant to aging and to phase separation, and/or can substantially solubilize and or stabilize active ingredients. Pharmaceutical and cosmetic compositions with potentially enhanced skin delivery and their uses are also provided.

Priority: US20070954525P Applic. Date: 2007-08-07

Inventor: TAMARKIN DOV [IL]; KEYNAN RITA [IL]; SCHUZ DAVID [IL]; BERMAN TAL [IL]

Title: Halogenated oxime derivatives and the use therof as latent acids

Applicant/Assignee:

Application No.: 12/154333   Filing Date: 22/May/2008

Abstract:

Compounds of the formula I or II wherein R1 is C1-C10haloalkylsulfonyl, halobenzenesulfonyl, C2-C10haloalkanoyl, halobenzoyl

R2 is halogen or C1-C10haloalkyl

Ar1 is phenyl, biphenylyl, fluorenyl, naphthyl, anthracyl, phenanthryl, or heteroaryl, all of which are optionally substituted

Ar'1 is for example phenylene, naphthylene, diphenylene, heteroarylene, oxydiphenylene, phenylene-D-D1-D-phenylene or -Ar''1-A1-Y1-A1-Ar''1-

wherein these radicals optionally are substituted

Ar''1 is phenylene, naphthylene, anthracylene, phenanthrylene, or heteroarylene, all optionally substituted

A1 is for example a direct bond, -O-, -S-, or -NR6-

Y1 inter alia is C1-C18alkylene

X is halogen

D is for example -O-, -S- or -NR6-

D1 inter alia is C1-C18alkylene

are particularly suitable as photolatent acids in ArF resist technology.

Priority: EP20030405103 Applic. Date: 2003-02-19; EP20030405130 Applic. Date: 2003-02-27; EP20030405432 Applic. Date: 2003-06-17; US2005-543429 Applic. Date: 2005-07-26; WO2004EP50096 Applic. Date: 2004-02-09

Inventor: YAMATO HITOSHI [JP]; ASAKURA TOSHIKAGE [JP]; MATSUMOTO AKIRA [JP]; MURER PETER [CH]; HINTERMANN TOBIAS [CH]

Title: Reshapable device for fixation at a dental site

Applicant/Assignee:

Application No.: 11/890986   Filing Date: 08/Aug/2007

Abstract:

A reshapable retention device for insertion at a dental site and contact with adjacent dental surfaces, for the controlled delivery to the dental site of at least one material having a predetermined intraoral activity. The retention device comprises at least one matrix containing the material. The retention device is adapted for physically affixing at the dental site for at least a predetermined time period correlated to the delivery of a predetermined portion of the at least one matrix to the dental site in a controlled single, bi or multiphase pattern. The retention device comprises a first configuration in which the overall dimensions of the retention device are larger than at least one dimension of the dental site. The first configuration is reshapable to a second configuration in which at least one dimension of the retention device is reduced to enable physically affixing the retention device at the dental site. In the second configuration the retention device comprises a predetermined shape having contours for affixing at the dental surfaces.

Priority:

Inventor: JODAIKIN AHRON [IL]; JODAIKIN HILARY [IL]

Title: PREDOMINANTLY PLATELET-SHAPED, SPARINGLY WATER-SOLUBLE CALCIUM SALTS AND/OR COMPOSITE MATERIALS THEREOF COMPRISING THEM

Applicant/Assignee:

Application No.: 12/241718   Filing Date: 30/Sep/2008

Abstract:

The invention relates to sparingly water-soluble calcium salts and/or composite materials comprising them, characterized in that the calcium salts are present in the form of single crystals or in the form of particles comprising a multitude of said crystals and having a mean particle diameter in the region of below 1,000 nm, preferably below 300 nm, the calcium salt particles being predominantly platelet-like. The inventive calcium salts and/or composite materials comprising these calcium salts, owing to their composition and fine structure, are particularly suitable for promoting the restoration of bone and tooth material, especially enamel and dentine.

Priority: DE200610009799 Applic. Date: 2006-03-01; WO2006EP10235 Applic. Date: 2006-10-24

Inventor: KINTRUP LOTHAR [DE]; ESCHEN BURKHARD [DE]; HERMANN MARTINA [DE]; FRANKE HOLGER [DE]

Title: Dental Appliance Cleansing Composition

Applicant/Assignee:

Application No.: 12/189160   Filing Date: 10/Aug/2008

Abstract:

A novel and safe composition has been discovered that is effective for cleaning dental appliances (e.g. removable braces, retainers, dentures, etc.). This composition bleaches, disinfects, and deodorizes the appliance, while removing plaque that has accumulated on the appliance during wear. The composition comprises a chloramine bleaching agent that liberates hypochlorous acid upon contact with water, a surfactant, a water-soluble carboxylic acid and an alkaline base to produce effervescence and regulate pH, a sequestering agent for alkaline earth metal ions, a drying agent, and an indicator dye that signifies the end of the cleansing process. In a preferred method of using this invention, the premixed components are added to water, and the dental appliance is submerged in the resulting effervescent solution until a color change indicates that cleaning is complete. This invention provides a safe, effective, and convenient method for cleansing and disinfecting dental appliances.

Priority: US20070954942P Applic. Date: 2007-08-09

Inventor: MUZIK LYNN [US]; CONLEY NICHOLAS [US]

Title: Heteroaryl compounds, compositions thereof, and methods of treatment therewith

Applicant/Assignee:

Application No.: 11/975657   Filing Date: 18/Oct/2007

Abstract:

Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.

Priority: US20060853135P Applic. Date: 2006-10-19

Inventor: MORTENSEN DEBORAH SUE [US]; DELGADO MEDEROS MARIA MERCEDES [US]; SAPIENZA JOHN JOSEPH [US]; ALBERS RONALD J [US]; CLAREEN STEVEN SPENCER [US]; SCHWARZ KIMBERLY LYN [US]; PARNES JASON SIMON [US]; RIGGS JENNIFER R [US]; PAPA PATRICK WILLIAM [US]; HEGDE SAYEE GAJANAN [US]; MCKENNA JEFFREY MARK [GB]

Title: Modulators of muscarinic receptors

Applicant/Assignee:

Application No.: 12/215367   Filing Date: 26/Jun/2008

Abstract:

The modulator compounds described herein modulate muscarinic receptors and are useful for treating muscarinic receptor mediated diseases.

Priority: US2004-005944 Applic. Date: 2004-12-07; US20030528049P Applic. Date: 2003-12-09

Inventor: GROOTENHUIS PETER D J [US]; BLANCO MIGUEL GARCIA-GUZMAN [US]; MAKINGS LEWIS R [US]; LONDO PHILIP MARTIN [US]

Title: HEADSET MADE FROM RECYCLABLE ISOLATING MATERIALS

Applicant/Assignee:

Application No.: 11/838957   Filing Date: 15/Aug/2007

Abstract:

Headset made from recyclable, disposable and isolating materials such as, for example, paper, cardboard and the like. The headset may comprise ear-members integrated with ear-fasteners and an oblong connecting strip made from isolating materials that may be connected to an ear-member at each end. The ear-members and the connecting-strip may hold at least one speaker connected by conductive-means to an audio player, where each speaker may be seated substantially at the central area of each ear-member. The ear-fasteners may fasten the headset to a user's ear-auricle to enable holding the entire headset over the user's head.

Priority:

Inventor: SCHAPIRO EDUARDO [IL]

Title: COMPOUNDS AND COMPOSITIONS USEFUL IN THE TREATMENT OF NEOPLASIA

Applicant/Assignee: NIPRI LIMITED

Application No.: 11/718314   Filing Date: 31/Oct/2004

Abstract:

There is described compounds for use in therapy, said compounds being defined by Formula (1): There is also described an anti-proliferative composition comprising one or more compounds according to Formula (1), and a method of treatment of neoplasia comprising the administration of such a compound or composition.

Priority: GB20040024051 Applic. Date: 2004-10-29; WO2005GB04190 Applic. Date: 2005-10-31

Inventor: MCCLAY ALLEN [GB]; WAUGH DAVID [GB]; ARMSTRONG PAUL [GB]; DELBEDERI ZOICA [GB]; HIGGINS CATHERINE [IE]; VAN DEN BERG HENDRIK [GB]; JOHNSTON PATRICK [GB]; WATTERS WILLIAM [GB]; MCGAREL KELLY [GB]; MILS TIMOTHY [GB]

Title: ANTI-MICROBIAL DENTAL IMPRESSION MATERIAL

Applicant/Assignee:

Application No.: 12/093869   Filing Date: 09/Nov/2006

Abstract:

The invention relates to plastics which are self-disinfecting. The invention relates in particular to polyether or silicone based dental plastics and impression materials in which a biocidal material is incorporated. The dental impression material ace. to the invention comprises at least a polymerizable base paste BP and a non-aqueous catalyst paste CP, wherein the base paste BP comprises about 0.001 to about 10% by weight of a water-stable anti-microbial agent. Preferred anti-microbial agents are selected from the group consisting of Hexitidin, Cetypyridininumcloride (CPC), Chlorhexidine and its derivates (CHX) and Triclosan.

Priority: EP20050025182 Applic. Date: 2005-11-17; WO2006US43770 Applic. Date: 2006-11-09

Inventor: KLETTKE THOMAS [DE]; KAPPLER OLIVER [DE]; HAEBERLEIN INGO R [DE]

Title: Ultrasonic scaler

Applicant/Assignee:

Application No.: 11/889465   Filing Date: 13/Aug/2007

Abstract:

A RFID (Radio Frequency Identification) reader is installed in the main unit of an ultrasonic scaler, which synchronizes with the antenna installed in the handpiece. Inside of The TIP (Insert or Piezo hand piece) consists of a tag, which uses RFID technology to read, write, and identify the information of the insert or tip. This provides the medical clinicians useful operation assistance, the necessary evidence on when to change to a new insert or tip, and to prevent improper usage of the insert or tip.

Priority:

Inventor: TSAI CHIH-I [TW]

Title: Dental compositions for coating restorations and tooth surfaces

Applicant/Assignee:

Application No.: 12/151854   Filing Date: 12/May/2008

Abstract:

Dental compositions comprising a polymerizable compound, filler system of nanometer-sized silica particles, and polymerization system capable of being activated by light are provided. The compositions further contain a solvent such as a mixture of 1-butanol and acetone and may contain water. The nanometer-sized silica particles, having an average particle size of about 1 nm to about 100 nm, are uniformly dispersed within the resin. The compositions can be applied as a polish, sealant, bleach guard, or other coating material to the surfaces of dental restorations and teeth. Self-etching and non-self-etching compositions are provided. The cured coating forms a protective, durable film that enhances the shine and luster of the restorations and teeth.

Priority: US20070928766P Applic. Date: 2007-05-11

Inventor: HUO XIN [US]; O'CONNOR MICHAEL [US]; SIZE ROBERT [US]

Title: Antagonists of the bradykinin B1 receptor

Applicant/Assignee: AMGEN INC

Application No.: 12/082395   Filing Date: 09/Apr/2008

Abstract:

The present invention relates to a method of treating, preventing, or ameliorating a disease or condition associated with or mediated by B1 activity that involves administering a composition of matter containing bradykinin B1 receptor antagonist peptides conjugated to a multivalent vehicle, including peptides conjugated to multivalent PEG. The method can be used therapeutically or prophylactically against diseases or conditions, such as inflammation or pain, linked to the bradykinin B1 receptor.

Priority: US2004-972236 Applic. Date: 2004-10-21; US20030513913P Applic. Date: 2003-10-22; US20040538929P Applic. Date: 2004-01-24

Inventor: NG GORDON [US]; LI YUE-SHENG [US]; GEGG COLIN V [US]; ASKEW JR BENNY C [US]; STORZ THOMAS [US]; LU YUELIE [US]; D AMICO DERIN C [US]; JAROSINSKI MARK A [US]; LIU CHUAN-FA [US]; HUANG QI [US]

Title: THERAPEUTIC PRO-APOPTOTIC BH3-LIKE MOLECULES AND METHODS FOR GENERATING AND/OR SELECTING THE SAME

Applicant/Assignee: THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH

Application No.: 11/993829   Filing Date: 23/Jun/2006

Abstract:

The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.

Priority: US20050693644P Applic. Date: 2005-06-24; WO2006AU00888 Applic. Date: 2006-06-23

Inventor: COLMAN PETER MALCOLM [AU]; HUANG DAVID CHING SIANG [AU]; LEE ERINNA FAITH [AU]; FAIRLIE WALTER DOUGLAS [AU]

Title: SOLID FORMS COMPRISING 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL, COMPOSITIONS THEREOF, AND USES THEREWITH

Applicant/Assignee:

Application No.: 12/200146   Filing Date: 28/Aug/2008

Abstract:

Solid forms comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro-phenylamino)-9H-purin-2-ylamino]-cyclohexan-1-ol, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed.

Priority: US2007-977759 Applic. Date: 2007-10-26; US20060854757P Applic. Date: 2006-10-27

Inventor: BEAUCHAMPS MARIE G [US]; CAMERON LOUISE MICHELLE [US]; HILGRAF ROBERT [US]; KOTHARE MOHIT ATUL [US]; SAINDANE MANOHAR T [US]; XU JEAN [US]

Title: ALTERNATE MORPHEEIN FORMS OF ALLOSTERIC PROTEINS AS A TARGET FOR THE DEVELOPMENT OF BIOACTIVE MOLECULES

Applicant/Assignee: FOX CHASE CANCER CENTER

Application No.: 12/142435   Filing Date: 19/Jun/2008

Abstract:

A composition having an agent adapted to affect a multimeric protein by binding to a binding site of the multimeric protein and thereby affecting an equilibrium of units, wherein the multimeric protein has an assembly having a plurality of said units, wherein each of the units has a first complementary surface and a second complementary surface and wherein the first complementary surface of one unit is associated with the second complementary surface of another unit, provided that the assembly is at least one of different quaternary isoforms on a condition that in the multimeric protein (1) a structure of each of the units determines a structure of the different quaternary isoforms, (2) the units are in the equilibrium and (3) the structure of the different quaternary isoforms influences a function of the multimeric protein.

Priority: US2006-327762 Applic. Date: 2006-01-06; WO2004US21722 Applic. Date: 2004-07-07; US20030485253P Applic. Date: 2003-07-07; US20040577312P Applic. Date: 2004-06-04; US20050690649P Applic. Date: 2005-06-15

Inventor: JAFFE EILEEN K [US]

Title: Tranexamic acid formulations

Applicant/Assignee: XANODYNE PHARMACEUTICALS, INC

Application No.: 12/228489   Filing Date: 13/Aug/2008

Abstract:

Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith.

Priority: US2005-072194 Applic. Date: 2005-03-04; US20040550113P Applic. Date: 2004-03-04; US20040592885P Applic. Date: 2004-07-30

Inventor: MOORE KEITH A [US]; HEASLEY RALPH A [US]; GREIWE JEFFREY S [US]

Title: Dental adhesive

Applicant/Assignee:

Application No.: 12/148572   Filing Date: 21/Apr/2008

Abstract:

Non-aqueous dental adhesive comprising a mixture containing (i) one or more polymerizable monomers optionally containing an acidic group, (ii) a polymerization initiator, and (iii) a thermal polymerization inhibitor of the following formula (I): wherein R'1 represents a hydrogen atom, or a saturated hydrocarbon group having 1 to 18 carbon atoms. R'2, which may be the same or different if more than one R'2 is present, independently represent a saturated hydrocarbon group having 1 to 18 carbon atoms, and c represents an integer of from 1 to 4, and (iv) optionally an organic solvent.

Priority: WO2006EP10051 Applic. Date: 2006-10-18; US2004-493721 Applic. Date: 2004-04-26

Inventor: KLEE JOACHIM E [DE]; LEHMAN UWE [DE]

Title: Scalable Process for Protein Purification

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 11/922591   Filing Date: 20/Jun/2006

Abstract:

The invention provides a process for the purification recombinantly expressed, self-assembled VLP from the homogenate of a bacterial host, wherein the process can be scaled up to a commercial production scale in a cost effective manner. The process comprises a first chromatography using an anion exchange matrix, a second chromatography using hydroxyapatite and, optionally, a size exclusion chromatography. VLP preparations obtained by the process of the invention are essentially free of endotoxin contaminations.

Priority: EP20050105513 Applic. Date: 2005-06-21; WO2006EP63373 Applic. Date: 2006-06-20

Inventor: RICHTER SUSANNE [CH]; TOPELL SIMON [CH]

Title: One-way valve with flapper concept for vacuum bag

Applicant/Assignee:

Application No.: 12/075755   Filing Date: 13/Mar/2008

Abstract:

A one-way valve allows air to be drawn from a collapsible, flexible, airtight bag using a vacuum source. When the vacuum source is removed, the one-way valve prevents air from reentering the bag. The valve assembly comprises: a valve base comprising an opening, a seat disposed along a periphery of the opening, a flange surrounding the seat, and first and second pivot supports

a flapper comprising a diaphragm that is deformable and overlies the opening

and a cap pivotably supported by the first and second pivot supports for pivoting between first and second angular positions, the cap comprising at least one vent hole. The cap maintains the diaphragm in contact with the seat along an entire perimeter of the seat when the cap is in the first angular position and does not maintain the diaphragm in contact with the seat along its entire perimeter when the cap is in the second angular position.

Priority: US20070966061P Applic. Date: 2007-08-24

Inventor: PHAM LINH [US]

Title: REDUCTION IN BACTERIAL COLONIZATION BY ADMINISTERING BACTERIOPHAGE COMPOSITIONS

Applicant/Assignee: INTRALYTIX, INC

Application No.: 12/264582   Filing Date: 04/Nov/2008

Abstract:

The present invention provides a method for reducing the risk of bacterial infection or sepsis in a susceptible patient by treating the susceptible patient with a pharmaceutical composition containing bacteriophage of one or more strains which produce lytic infections in pathogenic bacteria. Preferably, treatment of the patient reduces the level of colonization with pathogenic bacteria susceptible to the bacteriophage by at least one log. In a typical embodiment, the susceptible patient is an immunocompromised patient selected from the group consisting of leukemia patients, lymphoma patients, carcinoma patients, sarcoma patients, allogeneic transplant patients, congenital or acquired immunodeficiency patients, cystic fibrosis patients, and AIDS patients. In a preferred mode, the patients treated by this method are colonized with the pathogenic bacteria subject to infection by said bacteriophage.

Priority: US2003-724900 Applic. Date: 2003-12-02; US2001-757685 Applic. Date: 2001-01-11; US20000175377P Applic. Date: 2000-01-11; US20000205240P Applic. Date: 2000-05-19; US20000175416P Applic. Date: 2000-01-11; US20000175415P Applic. Date: 2000-01-11

Inventor: MORRIS J GLENN [US]; SULAKVELIDZE ALEXANDER [US]; ALAVIDZE ZEMPHIRA [GE]; PASTERNACK GARY R [US]; BROWN TORREY C [US]

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 12/082389   Filing Date: 09/Apr/2008

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2007-706088 Applic. Date: 2007-02-13; US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]

Title: Antibacterial peptides and analogues thereof

Applicant/Assignee:

Application No.: 11/632449   Filing Date: 13/Jul/2005

Abstract:

Antibacterial peptides and their multimeric analogues, with a wide range of action and low haemolytic activity are described. In particular, the peptide molecules exhibit a high antimicrobial activity against numerous bacterial species, with reduced cytotoxicity and a low haemolysis rate. The molecules of the invention are advantageously usable as therapeutic agents and coadjutants against infections caused by strains that are resistant to common antibiotics.

Priority: IT2004RM00349 Applic. Date: 2004-07-13; WO2005IT00397 Applic. Date: 2005-07-13

Inventor: BRACCI LUISA [IT]; GIULIANI ANDREA [IT]; PINI ALESSANDRO [IT]; NERI PAOLO [IT]

Title: BIOLOGICAL MATERIALS AND USES THEREOF

Applicant/Assignee: PHOTOBIOTICS LIMITED

Application No.: 12/089406   Filing Date: 06/Oct/2006

Abstract:

Priority: GB20050020436 Applic. Date: 2005-10-07; WO2006GB03733 Applic. Date: 2006-10-06

Inventor: DEONARAIN MAHENDRA [GB]; YAHIOGLU GOKHAN [GB]; BHATTI MANPREET [GB]

Title: DENTIFRICE COMPOSITION CONTAINING SILICONE OIL BEADS

Applicant/Assignee:

Application No.: 11/841183   Filing Date: 20/Aug/2007

Abstract:

Dentifrice composition and method of using such dentifrice composition to ameliorate dry mouth, where the dentifrice composition includes an orally acceptable vehicle having distributed therein silicone oil beads, and wherein the dentifrice composition has a viscosity of at least about 20,000 centipoise.

Priority:

Inventor: DEPIERRO KAREN [US]; SANTARPIA III RALPH PETER [US]; CURTIS JOHN PIERRE [US]; NILES HOLLANDRA [US]; DARCY-SIEGEL JOANN [US]; BLACKWELL BERNIE L [US]

Title: Pharmaceutical Compositions for Treating or Preventing Bone Conditions

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Application No.: 11/884525   Filing Date: 16/Feb/2006

Abstract:

Provided herein is a pharmaceutical composition for treating, preventing or ameliorating a bone or cartilage condition and methods of making and using the same.

Priority: US20050653722P Applic. Date: 2005-02-16; WO2006US05473 Applic. Date: 2006-02-16

Inventor: SOO CHIA [US]; TING KANG [US]; KURODA SHUNICHI [JP]; WU BEN [US]

Title: Variable temperature dental irrigator

Applicant/Assignee:

Application No.: 11/894019   Filing Date: 20/Aug/2007

Abstract:

Variable temperature (operator controlled) dental irrigator constructed of three pieces of stainless steel or high-grade aluminum housing two water supply tubes (cold and hot) sealed with O-Rings. The calibrated temperature control valve located on the discharge end of the dental irrigator allows the user (dentist or technician) to adjust the water spray from the irrigator to suit the patient's comfort desire. An additional feature of the irrigator is the interchangeable discharge jets (tips) that may be screwed on/off the main irrigator body for sterilization.

Priority:

Inventor: CORNELIUS STEVEN LOUIS [US]

Title: COMPOSITIONS AND METHODS FOR SMOKING CESSATION

Applicant/Assignee: MODUS BIOLOGICAL MEMBRANES LTD

Application No.: 11/658665   Filing Date: 25/Jul/2005

Abstract:

The invention discloses a method and a composition for smoking cessation or for promoting smoking cessation in individual smokers. The compositions described contain phosphatidic acid as the active ingredient.

Priority: US20040591261P Applic. Date: 2004-07-27; US20050659095P Applic. Date: 2005-03-08; WO2005IL00789 Applic. Date: 2005-07-25

Inventor: SHENFELD AVNER [IL]

Title: Bridged polycyclic compound based compositions for coating oral surfaces in pets

Applicant/Assignee:

Application No.: 12/228262   Filing Date: 11/Aug/2008

Abstract:

A pharmaceutically active agent, a pharmaceutically active agent carrier and method of use thereof are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two pharmaceutically active agents may be associated with the bridged polycyclic compound. In some embodiments, one or more bridged polycyclic compounds may be applied to an oral surface of an animal (e.g., canine, feline) such that an oral malady may be inhibited and/or ameliorated.

Priority: US20070964312P Applic. Date: 2007-08-10; US20070965154P Applic. Date: 2007-08-17; US20080029332P Applic. Date: 2008-02-16; US20080074494P Applic. Date: 2008-06-20

Inventor: WHITEFORD JEFFERY A [US]

Title: UPRIGHT VACUUM CLEANER

Applicant/Assignee: MIELE & CIE. KG

Application No.: 12/199316   Filing Date: 27/Aug/2008

Abstract:

An upright vacuum cleaner for cleaning a surface. The vacuum cleaner includes an upper body having a dust collection container, a base unit having a suction mouth and a carriage for moving the base unit on the surface. A motor-fan unit is included and is disposed outside the upper body. The motor-fan unit is operable to create a partial vacuum on the surface. A combined coaxial conduit is disposed in a transition region to the upper body. The combined coaxial conduit includes a first air conduit from the suction mouth to the upper body and a second air conduit from the upper body to the motor-fan unit.

Priority: DE200710040949 Applic. Date: 2007-08-30

Inventor: ISERINGHAUSEN TINA [DE]; MERSMANN UDO [DE]

Title: Method and apparatus for alleviating nasal congestion

Applicant/Assignee:

Application No.: 11/896716   Filing Date: 05/Sep/2007

Abstract:

The present invention relates generally to the field of treatments for nasal congestion, and in particular, to a method and apparatus for alleviating nasal congestion in a patient by mechanically stimulating the sneezing reflex in the patient to urge drainage of the nasal passageways. The method includes inserting an instrument having a work tip portion provided with at least one filament into the nostril of the patient. The nasal mucosa of the patient is then probed with the at least one filament to stimulate in the patient the sneeze reflex. This probing action causes the patient to sneeze. With the patient's mouth closed, the sneeze urges at least one of mucus, fluid and debris in the nasal passages of the patient to be forcibly expelled through the nostrils of the patient thereby draining the nasal cavity of the patient. The instrument used in the performance of this method includes a handle portion upon which the work tip portion is carried. The handle portion may be integrally formed with the work tip portion or releasably attachable thereto. The instrument is further provided with a physical stop associated with one of the work tip portion and the handle portion to prevent injury resulting from the working tip portion being inserted too deeply into the nasal passages of the patient.

Priority:

Inventor: WORSOFF MAYA [CA]

Title: SLEEP APPLIANCE

Applicant/Assignee:

Application No.: 12/252848   Filing Date: 16/Oct/2008

Abstract:

A dental oral appliance for use with patients who suffer with sleep disorders, to reduce or eliminate snoring and to open the airway for a sleeping individual who suffers with obstructive sleep apnea. The appliance covers the inside (lingual) of the upper teeth and has an open palate. Retention for the appliance is provided by either clasps placed over the upper right and left molars and a retainer in the anterior area or by an occlusal coverage of the upper teeth. A raised incisor ramp that extends from the incisal tip (biting edge) of the incisors toward the lingual, or posterior raised ramps, separate the posterior teeth to reduce spasm on the temporalis muscle. A transverse, transpalatal member, which extends from the inside (lingual) of the upper right molars to the inside of the upper left molars, covers the tongue, preventing it from moving upward or backward during sleep, opening the airway.

Priority: US2005-165641 Applic. Date: 2005-06-23

Inventor: KEROPIAN BRYAN [US]

Title: Protective guards and method of using same

Applicant/Assignee:

Application No.: 11/897278   Filing Date: 29/Aug/2007

Abstract:

A method and apparatus for protecting a user's mouth from discomfort caused by installed dental brackets of the character having a plurality of bracket members attached to the teeth of the user with cooperating wire support members attached to the brackets. The apparatus includes a plurality of uniquely configured protective guards that can be quickly and easily connected to and removed from the bracket members of the installed dental bracket. The protective guards are preferably constructed from a soft, stretchable material and comprise an end guard, a side guard, a corner guard and a front guard, each of which can be readily, removably attached to the dental bracket at selected areas to protect the inside of the user's mouth from injury.

Priority:

Inventor: ZAND FARNAZ [US]

Title: DISPENSING CARTRIDGE

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/262961   Filing Date: 31/Oct/2008

Abstract:

A dispensing cartridge, particularly for dental impression materials, formed from a plastic material having at least one inlet and at least one outlet, and including a metal reinforcement tube.

Priority: EP20030013831 Applic. Date: 2003-06-18; US2004-867060 Applic. Date: 2004-06-14

Inventor: KNEE MICHAEL [DE]; MUELLER DIRK [DE]; WAGNER INGO W [DE]

Title: Adjustable tabletop air freshener

Applicant/Assignee:

Application No.: 11/785053   Filing Date: 13/Apr/2007

Abstract:

We describe an adjustable table-top air freshener composed of a case that comprises an internally hollow body, provided with four pairs of slots arranged in couples around the perimeter of its lateral wall, and a cover which presents through-holes in its surface. The case body is designed to hold four absorbent pieces of aromatizing product, executed in twos with a three-point star and circular configuration with alternately sunken and protruding portions on its perimeter edge, of a diameter slightly smaller than the inside diameter of the case body and stacked alternately in the interior of the case body, with a star-shaped piece occupying the bottom position. The cover presents the formation of ribs of a predetermined height protruding from its inner face, interposed respectively between successive openings, which assure the separation between said cover and the absorbent piece located in the upper position.

Priority: ES20060001877U Applic. Date: 2006-08-09

Inventor: TORRES DAVID FERNANDEZ [ES]

Title: ERICACEA EXTRACTS FOR COMBATING SKIN AGING

Applicant/Assignee: L'OREAL

Application No.: 12/270161   Filing Date: 13/Nov/2008

Abstract:

Extracts of plants of the Ericacea family are administered to individuals to combat the signs of aging of the skin, e.g., wrinkles and fine lines, for example by inhibiting the expression of metalloproteases, by inhibiting collagen degradation, or by inhibiting UV-induced skin degradation.

Priority: FR20000012737 Applic. Date: 2000-10-05; US2001-970797 Applic. Date: 2001-10-05

Inventor: FAGOT DOMINIQUE [FR]

Title: HETEROCYCLODIAZEPINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE

Applicant/Assignee: KALYPSYS, INC

Application No.: 12/200554   Filing Date: 28/Aug/2008

Abstract:

The present invention relates to compounds and methods useful as modulators of CB2 for the treatment or prevention of disease states including, but not limited to pain, autoimmune disease, malabsorption syndrome, pulmonary disease, osteoporosis, muscle spasm in cancer, neuromuscular disorder, and atherosclerosis progression.

Priority: US20070969174P Applic. Date: 2007-08-31

Inventor: GAHMAN TIMOTHY C [US]; ZHAO CUNXIANG [US]; LANG HENGYUAN [US]; MASSARI MARK EBEN [US]

Title: AMIDE DERIVATIVES AS TRPV1 ANTAGONISTS

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/188323   Filing Date: 08/Aug/2008

Abstract:

The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, and R3, are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20070954945P Applic. Date: 2007-08-09

Inventor: VASUDEVAN ANIL [US]; BROWN BRIAN S [US]; DAANEN JEROME F [US]; GOMTSYAN ARTHUR R [US]; JINKERSON TAMMIE K [US]; KEDDY RYAN G [US]; KORT MICHAEL E [US]; KYM PHILIP R [US]; MATULENKO MARK A [US]

Title: DECALINE-DERIVED COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS

Applicant/Assignee: UNIVERSITAT DORTMUND MAX-PLANCK-GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V UNIVERSITAT BERN

Application No.: 11/813129   Filing Date: 28/Dec/2005

Abstract:

The present invention relates to compounds having a decaline scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said decaline-derived compounds can be used for prophylaxsis and/or treatment of diabetes mellitus type I, diabetes mellitus type II, tuberculosis and other infectious diseases, proliferative diseases, cancer, neurodegenerative diseases, obesity, cognitive dysfunctions and metabolic syndromes.

Priority: EP20040031076 Applic. Date: 2004-12-31; WO2005EP14100 Applic. Date: 2005-12-28

Inventor: ODERMATT ALEX [CH]; WALDMANN HERBERT [DE]; SCHECK MICHAEL [DE]; KOCH MARCUS A [DE]

Title: Process for preparing low-viscosity allophanates containing actinically curable groups

Applicant/Assignee:

Application No.: 12/229116   Filing Date: 20/Aug/2008

Abstract:

The present invention relates to a process for preparing low-viscosity reaction products of polyisocyanates containing activated, ethylenically unsaturated groups which react, with polymerization, on exposure to actinic radiation.

Priority: DE200710040239 Applic. Date: 2007-08-25

Inventor: LUDEWIG MICHAEL [DE]; FISCHER WOLFGANG [DE]; KUCZEWSKI HELMUT [DE]

Title: Method of Recording and Saving of Human Soul for Human Immortality and Installation for it

Applicant/Assignee:

Application No.: 11/613380   Filing Date: 20/Dec/2006

Abstract:

The inventor shows that a human soul is only the information in human brain. He offers a method for re-writing the human brain on electronic chips. This method allows for the modeling of a human soul in order to achieve man immortality. This method does not damage the brain but works to extend and enhance it. This method of writing and saving of Human Soul includes: writing of views which person see in during his life by a micro video recorder to a portable memory

writing of sounds which person speaks and hears by microphone

writing of person physical conditions by micro sensors

writing of time and dates

writing of person body position and so on. An Installation utilized the Method is comprising devices: micro video camera located at man head, microphone, computer (chip) for data processing, portable memory located at an person body and connected to the portable memory

portable recorder for writing of life film located at the man body and connected to the computer and to the portable memory

micro sensors for writing of person physical and environment conditions

a clock for writing of time, the micro sensors for writing of men body positions

navigation system, long time memory high capability storage and so on.

Priority:

Inventor: BOLONKIN ALEXANDER ALEXANDROVICH [US]

Title: Z-filter media with reverse-flow cleaning systems and methods

Applicant/Assignee: DONALDSON COMPANY, INC

Application No.: 12/074157   Filing Date: 29/Feb/2008

Abstract:

A method for cleaning a filter having Z-media includes providing a filter having Z-media and cleaning the media construction by directing a pulse of compressed gas into the media construction through the downstream flow face. Filter elements useable with such methods include elements made of Z-media. An example system utilizing the method includes a gas turbine air intake system.

Priority: US2006-331392 Applic. Date: 2006-01-12; US2003-731564 Applic. Date: 2003-12-08; US20020432923P Applic. Date: 2002-12-11

Inventor: SPORRE TIMOTHY D [US]; ROTHMAN JIM C [US]; HANDLEY MICHAEL W [US]; RAETHER THOMAS D [US]

Title: Spray Device Having a Piezoelectric Element, and Use Thereof in Cosmetology and Perfumery

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/293053   Filing Date: 13/Mar/2007

Abstract:

Spray device comprising a piezoelectric element, a sonotrode having a base coupled to the piezoelectric element, and a tube extending as far as a horn, a drive circuit for vibrating the piezoelectric element, and a feed device for bringing the product to be sprayed up to the front face of the horn. The sonotrode mainly vibrates in a mode parallel to the tube, the horn being dimensioned so as not to flex along the longitudinal axis, without flexing when the drive circuit vibrates the piezoelectric element. This spray device is applicable in cosmetology and in perfumery.

Priority: FR20060002281 Applic. Date: 2006-03-15; WO2007FR00433 Applic. Date: 2007-03-13

Inventor: TRANCHANT JEAN-FRANCOIS [FR]; RICHER SYLVIE [FR]; SAUZADE JEAN-DENIS [FR]

Title: IMAGE PROCESSING SYSTEM WHICH CALCULATES AND DISPLAYS COLOR GRADE DATA AND DISPLAY IMAGE DATA

Applicant/Assignee: OLYMPUS OPTICAL CO., LTD

Application No.: 12/264056   Filing Date: 03/Nov/2008

Abstract:

An image processing system is used for dentistry. Upon creating a false tooth of a patient (59), a plurality of illuminating light of LEDs with different wavelengths emit light and a photographing apparatus (1A) photographs a tooth portion of the patient (59), thereby obtaining image data. The image data is sent to a dentistry filing system (2A) serving as a processing apparatus, and color reproducing data is obtained by calculation. The color reproducing data is sent to a dentistry factory (55) via a public line. Data is searched from a database (56) for calculating a ceramic compounding ratio, compound data of the ceramic false tooth is obtained, matching the color of the tooth portion of the patient (59), and the false tooth approximate to the tooth color of the patient (59) is created.

Priority: JP20020218864 Applic. Date: 2002-07-26; US2005-521779 Applic. Date: 2005-01-21; WO2003JP09381 Applic. Date: 2003-07-24

Inventor: KOMIYA YASUHIRO [JP]; WADA TORU [JP]; KONNO OSAMU [JP]; AJITO TAKEYUKI [JP]; NAKAMURA TOMOYUKI [JP]

Title: LANTIBIOTICS AND USES THEREOF

Applicant/Assignee:

Application No.: 12/176124   Filing Date: 18/Jul/2008

Abstract:

The present invention provides isolated lantibiotics that inhibit Gram negative and Gram positive microbes. The lantibiotic includes an amino acid sequence, wherein the amino acid sequence of the compound and the amino acid sequence of SEQ ID NO:21 or SEQ ID NO:22 have at least 80% identity. The lantibiotics have the characteristic of inhibiting growth of a Gram negative microbe in conditions that do not damage the outer membrane of the Gram negative microbe. The present invention also provides methods for making and using the lantibiotics.

Priority: US20070961374P Applic. Date: 2007-07-20

Inventor: O'SULLIVAN DANIEL J [US]; LEE JU-HOON [US]

Title: Dentifrice Compositions for Treating Xerostomia

Applicant/Assignee:

Application No.: 11/850955   Filing Date: 06/Sep/2007

Abstract:

This invention encompasses an oral composition for treating or preventing dry mouth with following benefits: antibacterial/anti-fungal efficacy, low irritancy, and moisture retention. The compositions can be a toothpaste, a mouth rinse or a spray and include one or more non-ionic surfactants, as foaming agents, one or more broad spectrum anti-microbial ingredient, such as chlorhexidine and cetylpyridinium chloride, and one or more oral surface adhesive polysaccharides that can encage cationic actives to help the deposition and retention of the agents onto oral surfaces and thus provide antimicrobial efficacy.

Priority:

Inventor: PILCH SHIRA [US]; MASTERS JAMES GERARD [US]

Title: FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES

Applicant/Assignee: KURARAY MEDICAL INC

Application No.: 11/910319   Filing Date: 30/Mar/2006

Abstract:

The invention provides a fluoride ion releasing dental composition including an inorganic powder (a)

a fluoride ion releasing material (b)

a monomer (c)

and a polymerization initiator (d), in which the inorganic powder (a) is made of composite particles in which a layer of polysiloxane is formed on surfaces of substrate particles made of an inorganic material, and the fluoride ion releasing material (b) is at least one fluoride ion releasing material selected from the group consisting of ammonium fluoride, ammonium hydrogen fluoride, a metal fluoride, a polymer including, as a constitutional unit, a vinyl monomer having an acid fluoride group and a fluorine-containing phosphazene monomer. Since the fluoride ion releasing dental composition of this invention provides dentine with a high cariostatic property over a long period of time by gradually releasing fluoride ions, it is suitably used as a dental adhesive material, a dental filling material, a dental resin used for forming an abutment, a pit and fissure sealant, a dental coating material (manicure), a dental cement and so on.

Priority: JP20050097353 Applic. Date: 2005-03-30; WO2006JP306689 Applic. Date: 2006-03-30

Inventor: TAKEI MITSURU [JP]; KITA HIROTAKA [JP]; OHARA YASUJIRO [JP]

Title: TREATMENT FOR MUCOSITIS

Applicant/Assignee: HEPTAGEN LTD

Application No.: 11/814796   Filing Date: 25/Jan/2006

Abstract:

This invention relates to a medicament for protecting human mucosal cells from chemotherapy or radiotherapy induced cell death using formulations comprising adenosine or adenosine analogues as a reversible inhibitor of epithelial cell proliferation. The invention also relates to formulations containing adenosine for the prevention of or reduction in mucositis symptoms.

Priority: GB20050001476 Applic. Date: 2005-01-25; WO2006GB00241 Applic. Date: 2006-01-25

Inventor: EDWARDS RICHARD MARK [GB]; CLEMENTS JOHN MARTIN [GB]

Title: Controlled Surface Gelling of Mucoadhesive Polymers on Oral Mucosa

Applicant/Assignee:

Application No.: 11/850886   Filing Date: 06/Sep/2007

Abstract:

The present invention relates to an oral composition and method for alleviating the symptoms associated with xerostomia using encapsulated cation-releasing compounds formulated either intimately together or in separate compartments in a composition containing cation-sensitive mucoadhesive polymers.

Priority:

Inventor: PILCH SHIRA [US]; MASTERS JAMES GERARD [US]; DILLON RENSL [US]; VISCIO DAVID BENEDICT [US]

Title: Novel topical formulations of flucytosine and uses thereof

Applicant/Assignee:

Application No.: 12/229548   Filing Date: 25/Aug/2008

Abstract:

The invention relates to topical formulations and methods of use of flucytosine which demonstrate a clear advantage over currently available therapeutic regimens for the treatment and maintenance of fungal infections, particularly vulvovaginal candidiasis. The invention provides compositions which solve the long-standing need for antimicrobial agents which treat effectively resistant strains of Candida spp., especially C. albicans, C. glabrata, and C. tropicalis, and which pose limited risk of side effects, adverse reactions, or the development of resistant pathogens. The invention provides novel topical formulations of flucytosine designed to allow the active drug to act at the local application area, but which inhibit or moderate transdermal or transmucosal absorption of the drug, thus limiting systemic exposure.

Priority: US20070993635P Applic. Date: 2007-09-12; US20070009626P Applic. Date: 2007-12-31; US20080137349P Applic. Date: 2008-07-29

Inventor: WELSH SUSAN [US]; WOOD RICHARD D [US]

Title: PORTABLE COLOR CORRECTED OVER HEAD DENTAL LIGHT TO MATCH SHADES OF TEETH WITH TRUE CHROMATIC EFFICIENCY AND TO ACCELERATE TOOTH WHITENING

Applicant/Assignee:

Application No.: 11/852290   Filing Date: 08/Sep/2007

Abstract:

A portable color corrected light for the correct matching of tooth shades and acceleration of tooth whitening has been developed. In order to accurately match the tint and hue (true color) of teeth, the device provides 5500 to 6500 Kelvin, ambient-independent light with the ability to block or overwhelm ambient light to get a precise "color" reading of that tooth. The same light can accelerate the tooth whitening process with the addition of photo-accelerators to increase the decomposition of H2O2 or other peroxide whitening material. In addition, the same light can also serve as a dental operatory light which provides a closer to daylight illumination than conventional halogen dental lights.

Priority:

Inventor: WANG DANIEL [US]; CREAMER ALAN AUSTIN [US]

Title: COMPOSITION CONTAINING AZIRIDINO GROUPS AND USE THEREOF

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/278983   Filing Date: 08/Feb/2007

Abstract:

The invention relates to a composition comprising a prepolymer as component (A), wherein the prepolymer comprises aziridino groups and is characterized by an equivalent weight EW1, a crosslinker as component (B), wherein the crosslinker has a structure being different from the structure of the prepolymer and comprises aziridino groups and is characterized by an equivalent weight EW2, an initiator as component (C) being able to start curing of the composition, optionally filler(s) as component (D) and optionally additive(s) as component (E), wherein equivalent weight is defined as (molecular mass of the molecule)/(number of aziridino groups present in the molecule) and wherein EW1>EW2. The invention also relates to the use of the composition for coating, sealing, moulding, adhering, making impressions, producing a dental material.

Priority: EP20060003085 Applic. Date: 2006-02-15; WO2007US03389 Applic. Date: 2007-02-08

Inventor: KLETTKE THOMAS [DE]; FUEHRER CORNELIA B [DE]; BISSINGER PETER [DE]

Title: Methods For Reducing The Amount Of A Proinflammatory Substance In Animal Tissue Or Body Fluid

Applicant/Assignee: HILL'S PET NUTRITION, INC

Application No.: 12/094188   Filing Date: 17/Nov/2006

Abstract:

A method for reducing the amount of a proinflammatory substance present at an elevated level in animal tissue or body fluid by orally administering to the animal a proinflammatory substance reducing amount of a composition comprising at least one omega-3 fatty acid. The method is useful for reducing inflammation caused by elevated levels of proinflammatory substances including inflammation associated with an oral condition.

Priority: US20050738128P Applic. Date: 2005-11-18; WO2006US61037 Applic. Date: 2006-11-17

Inventor: SCHERL DALE SCOTT [US]; LOGAN ELLEN IRENE [US]; GROSS KATHY LYNN [US]

Title: Process for the dispersion of fine-particle inorganic powders in liquid media, with use of reactive siloxanes

Applicant/Assignee: BUHLER PARTEC GMBH

Application No.: 12/211989   Filing Date: 17/Sep/2008

Abstract:

The invention relates to a process for the dispersion of fine-particle surface-modified inorganic powders in liquid media, with use of siloxanes. A process for the preparation of a dispersion of inorganic particles in a liquid medium is described, in which inorganic particles which have been surface-modified so that they have at least one organic group on the surface are mixed in a liquid medium with an organosiloxane, where at least one organic group of the organosiloxane corresponds to the at least one organic group on the surface of the inorganic particles.

Priority: DE200710044302 Applic. Date: 2007-09-17

Inventor: STEINGROVER KLAUS [DE]; TABELLION FRANK [DE]; PILOTEK STEFFEN [DE]; KHIM MICHAEL [DE]

Title: Veterinary gurney or table incorporating a removable dental tray

Applicant/Assignee:

Application No.: 12/077754   Filing Date: 24/Mar/2008

Abstract:

A veterinary gurney or table having a base frame member supporting a mobility means, an elevation frame member mounted on the base frame, and a table member mounted on the elevation frame, allowing the elevation of the gurney or table to be locked at a selected height, one end of the gurney or table adapted to receive a slidable, securable dental tray for dental treatment of the animal while positioned on the gurney or table.

Priority: US20070919880P Applic. Date: 2007-03-26

Inventor: JEHN FRANK [US]

Title: Low-dusting investment composition material

Applicant/Assignee:

Application No.: 12/156937   Filing Date: 03/Jun/2008

Abstract:

A method for manufacturing a heat-resistant mold for manufacturing a dental restoration, wherein a wax model is manufactured in a conventional manner and wherein from a powdered heat-resistant material consisting of powdered particles coated with a hydrophobic material liquid at room temperature, with water or another mixing liquid, a slurry is prepared, wherein the slurry is applied to the wax model, and wherein the wax model covered slurry is subjected to a heating step, wherein the wax is burnt off.

Priority: NL20021020577 Applic. Date: 2002-05-10; WO2003NL00344 Applic. Date: 2003-05-09; US2005-514063 Applic. Date: 2005-10-24

Inventor: BETTMAN MARIJKE [NL]; VAN DER ZEL JOSEPH MARIA [NL]; GRINWIS THEODORUS JACOBUS [NL]

Title: TOOTH WHITENING METHODS AND APPARATUSES

Applicant/Assignee:

Application No.: 11/854714   Filing Date: 13/Sep/2007

Abstract:

Some disclosed tooth whitening methods comprise: painting a tooth whitening solution or gel including a bleaching agent onto teeth

and subsequent to the painting, disposing a conforming protective cover over the teeth. In some embodiments, the painting and disposing are performed under the non-interventional guidance of a session guide. In some tooth whitening article of manufacture embodiments, a tooth whitening solution or gel includes a bleaching agent, the tooth whitening solution or gel being configured for paint-on application onto teeth, and conforming protective cover is configured to be conformally disposed over the teeth after painting with the tooth whitening solution or gel. In some embodiments a tooth whitening solution or gel includes a bleaching agent at hydrogen peroxide-equivalent concentration of greater than or about 10 percent and does not include a reactive thickening agent.

Priority:

Inventor: SILVERMAN HARVEY N [US]

Title: STATHERIN PEPTIDE AND USE IN MEDICINE

Applicant/Assignee: QUEEN MARY & WESTFIELD COLLEGE

Application No.: 11/909342   Filing Date: 23/Mar/2006

Abstract:

A synthetic statherin peptide of general formula (I) X1X2X3X4X5X6X7X8X9X10X11X12X13X14X15X16X17X18X19X20X21 as defined herein is provided. The peptide finds application in the treatment of dent disease, dry mouth syndrome and in the formulation of pharmaceutical preparation comprising the peptide.

Priority: GB20050005975 Applic. Date: 2005-03-23; WO2006GB01085 Applic. Date: 2006-03-23

Inventor: ANDERSON PAUL [GB]; KOSORIC JELENA [GB]; WILLIAMS RALPH ANTHONY DAVID [GB]; HECTOR MARK P [GB]

Title: IMPLANTABLE PREPARATIONS COMPRISING GLOBIN, PROCESS FOR THEIR PRODUCTION, AND USES

Applicant/Assignee:

Application No.: 12/207621   Filing Date: 10/Sep/2008

Abstract:

Preparations comprising, especially, globin that is insoluble at neutral pH, and therefore at physiological pH, in which the globin has been obtained from whole blood by depigmentation in a medium that extracts or dissolves the haem but leaves the globin and the other constituents of proteinic nature in a substantially undissolved state, a process for the production of those preparations, and uses, especially for the filling, healing or regeneration of tissues, especially for chronic wounds and osseous healing or regeneration.

Priority: FR20070057501 Applic. Date: 2007-09-11; US20070971349P Applic. Date: 2007-09-11

Inventor: TAYOT JEAN-LOUIS [FR]; SAPIN FLORENT [FR]; BERNASCONI JEAN [FR]

Title: TISSUE TARGETED ANTIGENIC ACTIVATION OF THE IMMUNE RESPONSE TO CANCERS

Applicant/Assignee:

Application No.: 12/234569   Filing Date: 19/Sep/2008

Abstract:

The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of a treatment response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. The administration of the immunogenic compositions may be repeated relatively frequently over a relatively long period of time. In embodiments for intradermal or subcutaneous injection, dosages may be adjusted so that injections reproduce a consistent visible delayed inflammatory immune reaction at the successive site or sites of administration.

Priority: US2006-553972 Applic. Date: 2006-10-27; WO2005CA00812 Applic. Date: 2005-05-30; WO2007CA01915 Applic. Date: 2007-10-25; US20040577206P Applic. Date: 2004-06-07

Inventor: GUNN HAROLD DAVID [CA]

Title: BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR CONTROLLING BONE RESORPTION

Applicant/Assignee:

Application No.: 12/193529   Filing Date: 18/Aug/2008

Abstract:

A pharmaceutically active agent, a pharmaceutically active agent carrier and method of use thereof are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two pharmaceutically active agents may be associated with the bridged polycyclic compound. In some embodiments, a composition may be administered to a subject to control bone resorption, inflammation, and/or pain.

Priority: US20070965154P Applic. Date: 2007-08-17; US20080029332P Applic. Date: 2008-02-16; US20080074462P Applic. Date: 2008-06-20

Inventor: WHITEFORD JEFFERY A [US]

Title: American school lunch meals

Applicant/Assignee:

Application No.: 11/900445   Filing Date: 13/Sep/2007

Abstract:

A process for designing, and flavoring a shelf stable baked meal, cereal meal, freeze dried meal, chocolate meal, caramel meal, popsicle meal, and ice cream antithesis meal by taking a commercial brand name product and improving it by adding foodstuff nutrients to make it an American meal. When combined they meet the predetermined requirements of the National School Lunch program, the United States Department and the Dash Eating plan food intake requirements as defined in present invention. The said meals takes an existing commercial product, an example is candy bar and adds the necessary foodstuff components to the candy bar such that when combined the final product meets the food intake requirements of said American meal. The method of producing shelf stable various meals comprise using existing known methods and technologies of preparing foodstuff and keeping it fresh and ready to eat until opened.

Priority:

Inventor: SMITH LEON CURTIS [US]

Title: PROBES AND BIOFLUIDS FOR TREATING AND REMOVING DEPOSITS FROM TISSUE SURFACES

Applicant/Assignee:

Application No.: 12/234593   Filing Date: 19/Sep/2008

Abstract:

An endodontic probe is used to perform disinfection procedures on target tissues within root canal passages and tubules. The endodontic probe can include an electromagnetic radiation emitting fiber optic tip having a distal end and a radiation emitting region disposed proximally of the distal end. According to one aspect, the endodontic probe can include a porous structure that encompasses a region of the fiber optic tip excluding the radiation emitting region and that is loaded with biologically-active particles, cleaning particles, biologically-active agents, or cleaning agents for delivery from the porous structure onto the target tissues. Another aspect can include provision of the endodontic probe with an adjustable channel-depth indicator, which encompasses a region of the fiber optic tip besides the radiation emitting region and which is movable in proximal and distal directions along a surface of the fiber optic tip to facilitate the provision of depth-of-insertion information to users of the endodontic probe.

Priority: US20070995759P Applic. Date: 2007-09-28; US20070994891P Applic. Date: 2007-09-21; US20070994723P Applic. Date: 2007-09-20; US20070994571P Applic. Date: 2007-09-19

Inventor: RIZOIU IOANA M [US]; JONES JEFFREY W [US]; CHUEH PETER [US]

Title: COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/275954   Filing Date: 21/Nov/2008

Abstract:

The present invention is directed to compositions containing one or more polymerizable bisphosphonic acids and optionally one or more additional polymerizable components.

Priority: US2003-729497 Applic. Date: 2003-12-05; US20020437106P Applic. Date: 2002-12-30

Inventor: ABUELYAMAN AHMED S [US]

Title: INHIBITORS OF p38

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 12/184996   Filing Date: 01/Aug/2008

Abstract:

The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.

Priority: US2006-430512 Applic. Date: 2006-05-08; US2003-638126 Applic. Date: 2003-08-08; US2000-746722 Applic. Date: 2000-12-21; WO1999US10291 Applic. Date: 1999-05-11; US19990129099P Applic. Date: 1999-04-13; US19990127626P Applic. Date: 1999-04-01; US19980085053P Applic. Date: 1998-05-11

Inventor: SALITURO FRANCESCO [US]; GALULLO VINCENT [US]; BELLON STEVEN [US]; BEMIS GUY [US]; COCHRAN JOHN [US]

Title: Local Anesthetic Methods and Kits

Applicant/Assignee: NOVALAR PHARMACEUTICALS, INC

Application No.: 12/275556   Filing Date: 21/Nov/2008

Abstract:

Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.

Priority: SE19960002943 Applic. Date: 1996-08-07; US2003-668248 Applic. Date: 2003-09-24; US2002-155171 Applic. Date: 2002-05-28; US2001-852751 Applic. Date: 2001-05-11; US20000203800P Applic. Date: 2000-05-12; US20000235855P Applic. Date: 2000-09-27

Inventor: WEBER ECKARD [US]; KATZ HOWARD I [US]

Title: MUSCARINIC ACETYCHOLINE RECEPTOR ANTAGONISTS

Applicant/Assignee:

Application No.: 11/573099   Filing Date: 02/Feb/2007

Abstract:

Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.

Priority: US20040600213P Applic. Date: 2004-08-06; WO2005US27957 Applic. Date: 2005-08-05

Inventor: BUSCH-PETERSEN JAKOB [US]; PALOVICH MICHAEL R [US]; LAINE DRAMANE IBRAHIM [US]

Title: One-pack type dental adhesive composition

Applicant/Assignee: KABUSHIKI KAISHA SHOFU

Application No.: 12/230225   Filing Date: 26/Aug/2008

Abstract:

An object of the present invention is to provide a one-pack type dental adhesive composition which can exhibit excellent adhesion to any material, for example, dental ceramics, organic composites containing inorganic compounds, dental noble metals and dental non-noble metals, and also has excellent storage stability. Disclosed is a one-pack type dental adhesive composition comprising a silane coupling agent as a component (a), an acidic group-containing polymerizable monomer as a component (b), a sulfur atom-containing polymerizable monomer as a component (d), and other components.

Priority: JP20070239651 Applic. Date: 2007-09-14

Inventor: TANAKA HISAKI [JP]; FUJII TOSHIHIDE [JP]; YAMAGUCHI YUTAKA [JP]; DEGUCHI MIKITO [JP]

Title: Radiation curable methacrylate polyesters

Applicant/Assignee:

Application No.: 11/919743   Filing Date: 28/Apr/2006

Abstract:

A radiation curable composition comprising a (meth)acrylated polyester having unsaturated (meth)acrylic groups on the molecules, responding to formula (I) or formula (II) wherein each D, independently, represents ethylene or propylene, x, y is an integer from (1) to (50), each A, independently, represent hydrogen, alkyl, alkenyl, with the proviso that adjacent A's can be linked together to form a cycle, each B, independently, represents an alkylene or alkenylene chain, optionally comprising one or more ether bridges, each R, independently, represents hydrogen or methyl.

Priority: US20050677346P Applic. Date: 2005-05-04; WO2006EP04012 Applic. Date: 2006-04-28

Inventor: CHIAO JOHN JUN [US]; ARCENEAUX JOANN [US]

Title: ONE-PACKAGE DENTAL ADHESIVE COMPOSITION

Applicant/Assignee: TOKUYAMA DENTAL CORPORATION

Application No.: 12/276585   Filing Date: 24/Nov/2008

Abstract:

An adhesive composition comprising (A) a polymerizable monomer component containing not less than 5% by mass of an acidic group-containing polymerizable monomer, (B) a polyvalent metal ion-eluting filler, (C) a volatile organic solvent, and (D) water, wherein the polyvalent metal ion-eluting filler (B) is blended in such an amount that the amount of the polyvalent metal ions eluted out from the filler becomes 1.0 to 7.0 meq per gram of the polymerizable monomer component (A), the volatile organic solvent (C) is blended in an amount in a range of 30 to 150 parts by mass per 100 parts by mass of the polymerizable monomer component (A) and so as to satisfy 20.X parts by mass or more (X is a number representing the amount of elution of the polyvalent metal ions), and the water (D)

is blended in an amount of 3 to 30 parts by mass per 100 parts by mass of the polymerizable monomer component (A). The composition maintains a large strength of adhesion to the teeth, can be preserved in the form of one package, and can be used as a material for pre-treating the teeth and as a dental adhesive.

Priority: JP20060147203 Applic. Date: 2006-05-26; JP20060239951 Applic. Date: 2006-09-05; JP20060284322 Applic. Date: 2006-10-18; WO2007JP61148 Applic. Date: 2007-05-25

Inventor: MATSUSHIGE KOJI [JP]; OGURI MAKOTO [JP]; SHIMIZU SHIZUKA [JP]; SUZUKI TAKESHI [JP]

Title: Teething fingers

Applicant/Assignee:

Application No.: 11/901833   Filing Date: 19/Sep/2007

Abstract:

A teething device for use by an infant. The teething device has a base manufactured from a first predetermined material and the base has a first predetermined size and a first predetermined shape. There is at least one projection protruding from a first predetermined side of the base such that the at least one projection will fit in an infant's mouth. The at least one projection is manufactured from a second predetermined material and has a second predetermined size and a second predetermined shape. A handle member manufactured from a third predetermined material and has a third predetermined size and a third predetermined shape and the handle member protrudes from a second predetermined side of the base.

Priority:

Inventor: LETSCHE JANE [US]

Title: PET TOY FOR RETAINING REPLACEABLE TREATS, AND METHODS

Applicant/Assignee:

Application No.: 11/858675   Filing Date: 20/Sep/2007

Abstract:

Pet toys configured to accept an edible or chewable treat which can be readily replaced. The pet toys have a first portion and a second portion which releaseably engage to retain the edible treat with the toy until the treat is consumed or otherwise removed from the toy by the pet. When desired, the toy can be disassembled by removing the first portion from the second portion, new treats can be added to the toy, and the two portions reassembled.

Priority:

Inventor: MANN CHARLES DAVID [US]

Title: Auto-Titration of Positive Airway Pressure Machine With Feedback From Implantable Sensor

Applicant/Assignee: PAVAD MEDICAL, INC

Application No.: 12/235538   Filing Date: 22/Sep/2008

Abstract:

Systems and methods for detecting and treating an obstructive sleep apnea event are disclosed herein. The systems and methods may use an electrical output generating ionic polymer metal composite sensor attached to a region in an airway passage in an oral cavity. The electrical output may be wirelessly transmitted as a signal for indication of an obstructive sleep apnea event. The signal may be further analyzed by a positive airway pressure system for treatment of the obstructive sleep apnea event.

Priority: US2006-613027 Applic. Date: 2006-12-19; US2004-946435 Applic. Date: 2004-09-21; US2005-233493 Applic. Date: 2005-09-21; US2006-355927 Applic. Date: 2006-02-15; US20080055405P Applic. Date: 2008-05-22

Inventor: BHAT NIKHIL D [US]; HEGDE ANANT V [US]; YUNG CHARISSE M [US]; CHOI GEORGE Y [US]

Title: SEALING DISC WITH TAB FOR CLOSING A CONTAINER HAVING A PLUG OR CAP CLOSURE AND FABRICATION METHOD

Applicant/Assignee: MANUFACTURE GENERALE DE JOINTS

Application No.: 12/200364   Filing Date: 28/Aug/2008

Abstract:

Sealing disc (1) for closing a container having a plug or cap closure, comprising a support (2) to be positioned at the bottom of the plug or of the cap, joined by means of a temporary adhesive (7) to a membrane seal (3) to be sealed on the mouth of the container, the membrane seal (3) being provided on all or part of its thickness with a prolongation constituting a pull tab (4), characterized in that the whole surface of the tab is folded back on the face of the membrane seal (3) in contact with the corresponding face of the support (2).

Priority: FR20070057839 Applic. Date: 2007-09-25

Inventor: TRIQUET STEPHANE [FR]; BISCHOFF REMY [FR]

Title: Dental Optical Coherence Tomograph

Applicant/Assignee: SHOFU INC

Application No.: 12/085423   Filing Date: 22/Nov/2006

Abstract:

A dental optical coherence tomography apparatus for measuring tissue in a stomatognathic region of a living body or an artificial composition in the stomatognathic region as a measured object includes: a variable wavelength light source (15)

a light splitting portion (19) that splits light-source light emitted from the variable wavelength light source (15) into reference light (29) and measuring light (28)

an interference portion (19) that causes the measuring light (28) and the reference light (29) to interfere with each other, thereby generating interference light

a photodetection portion (41) that measures the interference light

and an arithmetic portion (27b) that generates an image of a measured object (22) by Fourier transforming or inverse Fourier transforming the intensity of the interference light, whose wavelength changes with time, that has been detected by the photodetection portion for each of the wavelengths. Accordingly, an optical coherence tomography apparatus applicable to dental measurement can be provided.

Priority: JP20050337372 Applic. Date: 2005-11-22; WO2006JP323279 Applic. Date: 2006-11-22

Inventor: YATAGAI TOYOHIKO [JP]; YASUNO YOSHIAKI [JP]; TAMURA MASAMI [JP]

Title: Oral Care Compositions Comprising Tropolone Compounds and Essential Oils and Methods of Using The Same

Applicant/Assignee:

Application No.: 12/329210   Filing Date: 05/Dec/2008

Abstract:

The present invention relates to oral care compositions suitable for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, comprising an oral care effective amount of at least one tropolone compound in combination with at least one essential oil, and a pharmaceutically acceptable oral carrier. This invention further relates to a method for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, by applying an oral care effective amount of the oral care composition to the oral cavity.

Priority: US2004-766366 Applic. Date: 2004-01-28; US2002-207726 Applic. Date: 2002-07-29

Inventor: PAN PAULINE [US]; FINNEGAN MARYBETH [US]; SOSHINSKY ANDRE [US]; ARVANITIS GEORGIA [US]; BERARDINI MICHAEL [US]

Title: Iodine-based oral antibacterial treatment methodology

Applicant/Assignee:

Application No.: 11/903583   Filing Date: 24/Sep/2007

Abstract:

An iodine-based oral antibacterial treatment methodology involves applying an effective amount of an iodine-based oral antibacterial treatment to the inside of a human or animal mouth in the gum area between the gum and a tooth wall. The delivered treatment includes available iodine, including molecular iodine, and an iodine free radical initiator selected from the group consisting of chloride ions, bromide ions and mixtures thereof. Animals include pets, such as dogs and cats, as well as farm animals having teeth, e.g., horses, cows, goats and the like, and zoo animals having teeth, such as chimps, baboons, tigers and the like.

Priority:

Inventor: GLEN JEFFREY D [US]

Title: PSEUDOMONAS EXOTOXIN A-LIKE CHIMERIC IMMUNOGENS FOR ELICITING A SECRETORY IGA-MEDIATED IMMUNE RESPONSE

Applicant/Assignee: OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES GENENTECH, INC

Application No.: 12/169438   Filing Date: 08/Jul/2008

Abstract:

This invention provides methods of eliciting a secretory IgA-mediated immune response in a subject by administering a Pseudomonas exotoxin A-like chimeric immunogens that include a non-native epitope in the Ib domain of Pseudomonas exotoxin. Compositions comprising secretory IgA antibodies that specifically recognize an epitope of HIV-1 also are provided.

Priority: US2003-659036 Applic. Date: 2003-09-09; US2000-462713 Applic. Date: 2000-05-12; WO1998US14336 Applic. Date: 1998-07-10; US19970056924P Applic. Date: 1997-07-11

Inventor: FITZGERALD DAVID J [US]; MRSNY RANDALL J [US]

Title: Sustained release dosage form for lubricating an oral cavity

Applicant/Assignee:

Application No.: 11/904333   Filing Date: 26/Sep/2007

Abstract:

Aspects of the invention include a sustained release dosage form that can be administered to an oral cavity, e.g., the mouth. In certain embodiments, the sustained release dosage form is formulated as a lozenge or gum that may be administered to an oral cavity for the purpose of providing lubrication therein. In certain embodiments, the sustained release dosage form not only provides lubrication to a mucosal surface of an oral cavity, but also provides for the sustained release of a flavoring and/or beneficial agent. Accordingly, in certain embodiments, the sustained release dosage form includes a water-insoluble polymer, e.g., ethylcellulose, an essential oil component, and an effective amount of a film forming binder, e.g., xanthan gum. In certain embodiments, the effective amount of the film forming binder and the type of film forming binder are selected so as to provide the sustained release dosage with the capability of lubricating one or more mucosal surfaces within an oral cavity when the dosage form is positioned therein. In certain embodiments, the sustained release dosage form is formulated in a manner sufficient to form a matrix that includes the various components of the sustained release dosage form, such that when positioned in an oral cavity the matrix slowly dissolves and thereby lubricates the oral cavity and/or delivers a flavoring and/or beneficial agent thereto. Methods of formulating such dosage forms and administering them to an oral cavity for the treatment of an adverse condition are also provided.

Priority:

Inventor: GIN JERRY B [US]; ROSS BENJAMIN F [US]

Title: DENTAL RINSING UNIT

Applicant/Assignee:

Application No.: 12/280437   Filing Date: 21/Feb/2007

Abstract:

The invention relates to a cleaning container (12) comprising an inlet (120) which is connected to the water container (11), and an outlet for connecting a suction tube (43), the outlet (122) being embodied as a hydrant (124) for a suction handpiece (42) applied to the suction tube (43). The cleaning container (12) can be filled with the water from the water container (11) especially by means of a negative pressure applied to the outlet when the suction tube (43) is connected.

Priority: DE200610008944 Applic. Date: 2006-02-23; WO2007EP51635 Applic. Date: 2007-02-21

Inventor: FREY HANS-PETER [DE]

Title: METHODS, DEVICES, SYSTEMS, ASSEMBLIES, AND KITS FOR TISSUE RETRACTION IN AN ORAL CAVITY

Applicant/Assignee: INDENTIV, LLC

Application No.: 12/239477   Filing Date: 26/Sep/2008

Abstract:

Provided herein is a retraction device for retracting soft tissue from the dental surfaces in the oral cavity of a patient. The retraction device is comprised of a topology conformable structure, where the topology conformable structure is adaptable to be delivered to the oral cavity in a constrained shape. The device can then undergo a conformation change in the oral cavity, where the device transforms into its unconstrained shape. The unconstrained shape of the device creates a useable working field in the oral cavity. The useable working field can provide increased accessibility to and/or visibility within the oral cavity. Also provided herein are methods for using the device and kits.

Priority: US20070975387P Applic. Date: 2007-09-26; US20080026989P Applic. Date: 2008-02-07; US20080081908P Applic. Date: 2008-07-18

Inventor: HINES CRAIG [US]; PONTYNEN CURTIS [US]

Title: METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 11/852003   Filing Date: 07/Sep/2007

Abstract:

The present invention relates to methods and compositions for treating diseases ameliorated by increased mucociliary clearance and mucosal hydration by administering an effective amount of a sodium channel blocker as defined herein and an osmolyte to a subject to a subject in need of increased mucociliary clearance and mucosal hydration.

Priority: US20060842963P Applic. Date: 2006-09-08; US20060842669P Applic. Date: 2006-09-07

Inventor: JOHNSON MICHAEL ROSS [US]; BOUCHER RICHARD C [US]; HIRSH ANDREW J [US]

Title: N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS

Applicant/Assignee: ACADIA PHARMACEUTICALS, INC

Application No.: 12/234582   Filing Date: 19/Sep/2008

Abstract:

Disclosed herein are isolated forms of the compounds of Formula (I), (II), (III), (IV) and (V), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, or ester thereof. Also disclosed are methods of inhibiting an activity of a serotonin receptor, methods inhibiting an activation of a serotonin receptor, and methods of alleviating or treating various disease conditions and side effects.

Priority: US20070974426P Applic. Date: 2007-09-21; US20080050976P Applic. Date: 2008-05-06

Inventor: ULDAM HENRIETTE KOLD [DK]; THYGESEN MIKKEL BOAS [DK]

Title: PYRAZOLO[5, 1-C] [1,2,4] TRIAZINES, METHODS FOR PREPARATION AND USE THEREOF

Applicant/Assignee: WYETH

Application No.: 12/233877   Filing Date: 19/Sep/2008

Abstract:

A pyrazolo[5,1-c][1,2,4]triazine compound of formula A: and pharmaceutically acceptable sats thereof. The multiply-substituted pyrazolo[5,1-c][1,2,4]triazine compounds of the invention selectively inhibit B-Raf kinase activity and are useful for treating disorders mediated by B-Raf kinase.

Priority: US20070994589P Applic. Date: 2007-09-20

Inventor: BERGER DAN MAARTEN [US]; DUTIA MINU DHANJISHA [US]; HOPPER DARRIN WILLIAM [US]; TORRES NANCY [US]

Title: Vanilloid receptor ligands and their use in treatments

Applicant/Assignee:

Application No.: 12/284586   Filing Date: 22/Sep/2008

Abstract:

Bicyclic 3,4-fused piperidine compounds, and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotizing agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.

Priority: US20070994759P Applic. Date: 2007-09-20

Inventor: NISHIMURA NOBUKO [US]; NORMAN MARK H [US]; TAMAYO NURIA [US]; TANG PHI [US]; BO YUNXIN Y [US]

Title: Shower head attachment with a pulsator used to clean teeth

Applicant/Assignee: HEALTH AND HYGIENE INC

Application No.: 11/900764   Filing Date: 13/Sep/2007

Abstract:

A valve for adjusting the flow of water through an oral irrigation device is connected to a shower head by a flexible conduit. The valve is located on a handle connected to a water-dispensing pick for cleaning teeth and gums. An impeller-type pump is provided in the flexible conduit to pulsate the water.

Priority:

Inventor: SHAW DANIEL A [US]

Title: ORAL HYGIENE SYSTEM

Applicant/Assignee: JEAN FINOLE, LLC

Application No.: 12/238512   Filing Date: 26/Sep/2008

Abstract:

An integrated oral health hygiene system including at least one oral health care product such as a tooth brush, dental floss and dental rinse/wash. In addition, the system includes instructions for using the oral health care product(s) and a coupon for providing a user access to at least one of discounted and complimentary medical professional services relating to oral health care.

Priority: US20070975656P Applic. Date: 2007-09-27

Inventor: LETANG RANDY D [US]; IRBY DALE [US]

Title: Process For Tooling For Manufacture Of A Composite Part Composite Stopper Obtained By Such A Process Or Such Tooling

Applicant/Assignee:

Application No.: 12/207805   Filing Date: 10/Sep/2008

Abstract:

This manufacturing process of a composite part (B), including a stamped body (11, 12) and an injected polymer material part (14), includes steps consisting of: a) placing a blank (1) of a body (11, 12) between a support (456) and a mold (31, 32), such that the said hollow part forms a pattern cavity (33) communicating with an opening (13) going through the blank (1)

b) stamping the blank (1) using a punch (8)

c) placing the holder (456) in a position in which it defines with the blank (1) at least one cavity (400) and in which there is at least one injection runner (50-60) leading to the said cavity (400). d) injecting the polymer material through the injection runner (50-60), said cavity (400) and said opening (13), so as to fill the said pattern cavity (33)

and e) removing the composite part (B) from the mold.

Priority: FR20070006819 Applic. Date: 2007-09-28

Inventor: RAMOS VICTOR [FR]

Title: FOAMABLE FLUORIDE ORAL CARE COMPOSITION

Applicant/Assignee:

Application No.: 11/865457   Filing Date: 01/Oct/2007

Abstract:

A dental fluoride foam composition comprising an aqueous solution of a water soluble fluoride ion releasable salt, a surfactant selected from the group consisting of nonionic surfactants, zwitterionic surfactants, betaine surfactants and mixtures thereof

and an orally compatible acidifying agent in an amount sufficient to adjust the pH of the composition to about 3 to about 5. The composition is stable at low temperatures and is a clear solution substantially free of precipitates when held at 4.4 DEG C. for 12 hours. When dispensed from a container into the trough of a dental tray, the composition forms a low density, rapidly collapsible foam which substantially liquefies in about 1 minute after being dispensed from the foam generating container and placed in contact with a patient's teeth.

Priority:

Inventor: JOZIAK MARILOU THERESA [US]; FISHER STEVEN WADE [US]

Title: Dental Treatment Compositions and Conformable Dental Treatment Trays Using the Same

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/329583   Filing Date: 06/Dec/2008

Abstract:

The present invention is a formable dental treatment tray utilizing poly(2-ethyl-2-oxazoline) and a gelatinous active. Blending of the active is accomplished by mixing the Poly(2-ethyl-2-oxazoline) with an active ingredient, such as a peroxide like hydrogen peroxide, carbamide peroxide, sodium perborate, or sodium percarbonate, usually also with water or an appropriate organic solvent. Peroxide concentrations in these new gels can reach a 30% concentration of hydrogen peroxide while maintaining a shelf life of six months at room temperature without developing peroxide decomposition. The gels are applied to an appropriate backing and dried to a gelatinous state. In use, the active is hydrated and regains adhesiveness. Then the tray is pressed and formed around a user's dental arch to form the customizable tray. Multiple active ingredients may be used, with or without peroxide, for accomplishing desired treatment regimens.

Priority: US2008-329582 Applic. Date: 2008-12-06; US2006-307463 Applic. Date: 2006-02-08

Inventor: JENSEN STEVEN D [US]; CAO DENSEN [US]

Title: Oral Compositions Containing Botanical Extracts

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/243669   Filing Date: 01/Oct/2008

Abstract:

The disclosure provides oral compositions having at least two botanical active ingredients derived from plants. The oral composition also includes an orally acceptable vehicle to deliver an effective amount of the at least two active ingredients in vivo. The botanical active ingredients provide particularly efficacious antimicrobial (antibacterial, antiviral, and/or antifungal), antioxidant, anti-inflammatory, anti-ageing, and or healing properties to the oral compositions.

Priority: US20070976508P Applic. Date: 2007-10-01

Inventor: CUMMINS DIANE [US]

Title: Oxime Ester Photoinitiators

Applicant/Assignee:

Application No.: 12/085383   Filing Date: 08/Nov/2006

Abstract:

Compounds of the formula (I), (II), and wherein R1, R2, R'2 and R'''2 for example are C1-C20alkyl

R3, R4, and R5 for example independently of one another are hydrogen or a defined substituent provided that at least one of R3, R4 or R5 is other than hydrogen or C1-C20alkyl

R6, R7, R8, R'6, R'7, R'8, R''6, R''7, R'''6 and R'''7 for example independently of one another have one of the meanings as given for R3, R4, and R5

and R9 for example is C1-C20alkyl

exhibit an unexpectedly good performance in photopolymerization reactions.

Priority: EP20050111539 Applic. Date: 2005-12-01; WO2006EP68202 Applic. Date: 2006-11-08

Inventor: MATSUMOTO AKIRA [JP]; TANABE JUNICHI [JP]; KURA HISATOSHI [JP]; OHWA MASAKI [JP]

Title: SELF-CUSTOMIZABLE DENTAL TREATMENT TRAYS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/865867   Filing Date: 02/Oct/2007

Abstract:

A self-customizable dental tray usable in a dental application is prepared as follows: providing a barrier layer in the shape of a dental treatment tray having a wall thickness of less than or about 1 mm

introducing a curable elastomeric material onto an impression-receiving surface of the barrier layer

placing the barrier layer having the curable elastomeric material onto the teeth so that the curable elastomeric material forms an impression layer

and allowing the curable elastomeric material to cure so as to form an impression layer having a teeth-receiving surface with contours adapted to conform with the teeth, said impression layer having a wall thickness of less than or about 1 mm. Optionally, the barrier layer is a liner that can be separated from a support tray that provides a tray shape to the liner.

Priority:

Inventor: ANDERSEN SCOT N [US]

Title: Respiratory Anaesthesia Apparatus with Device for Measuring the Xenon Concentration

Applicant/Assignee: L'AIR LIQUIDE SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE

Application No.: 12/097216   Filing Date: 11/Dec/2006

Abstract:

Apparatus for respiratory anaesthesia of a patient by administration of a gas containing gaseous xenon, with a main gas circuit which is open or closed and has an inhalation branch and an exhalation branch, means for supply of gaseous xenon to the inhalation branch of the main circuit, and means for determining the xenon concentration. The means for determining the xenon concentration comprise at least one hot-wire sensor having at least one electrically conducting wire in direct contact with the gaseous flow containing the xenon, calculating means that cooperate with the hot-wire sensor(s) in order to determine the xenon concentration (Xe %) in the flow, means for generating an electrical current in order to generate a current in at least one hot wire, and means for voltage measurement that can measure at least one voltage value at the terminal of at least one hot wire or at least one resistance arranged in series with at least one hot wire. The calculating means cooperate with the voltage measurement means in such a way as to determine the xenon concentration (Xe %).

Priority: FR20050053862 Applic. Date: 2005-12-14; WO2006FR51326 Applic. Date: 2006-12-11

Inventor: DAVIET CHRISTIAN [FR]; BLANDIN RICHARD [FR]; KISSI NOUREDDINE [FR]

Title: CONTINOUSLY ADJUSTABLE MANDIBULAR PROTRUSION SPLINT FOR TREATING SNORING AND OBSTRUCTIVE SLEEP APNOEA

Applicant/Assignee:

Application No.: 11/719680   Filing Date: 23/Nov/2005

Abstract:

The invention relates to a two-part mandibular protrusion splint (1) for preventing snoring and/or obstructive sleep apnoea, comprising a lower part (2) and an upper part (3), comprising shaping and flexurally rigid trays (2a, 3a) which are open towards the mandibula and maxilla respectively, where the bottom surfaces of the outsides of the two trays (2a, 3a) are connected to one another in such a way that they are continuously adjustable relative to one another in the longitudinal direction, and a corresponding ready-to-use set for the production or restoration of mandibular protrusion splints consisting of (i) shaping and flexurally rigid trays (2a, 3a) with preformed attachment elements on the outsides of each of the bottom surfaces

(ii) one or more adjustment screws (10) for connecting the attachment elements

and (iii) optionally use instructions.

Priority: DE200410058081 Applic. Date: 2004-12-01; DE200520015106U Applic. Date: 2005-09-24; WO2005DE02095 Applic. Date: 2005-11-23

Inventor: TOUSSAINT WINFRIED [DE]

Title: Cigarette Having Configured Lighting End

Applicant/Assignee: R.J. REYNOLDS TOBACCO COMPANY

Application No.: 11/868264   Filing Date: 05/Oct/2007

Abstract:

The lighting end or tip of the smoking article is configured in such a manner that the entire front or upstream face thereof does not lie in a plane that is generally perpendicular to the longitudinal axis of the smoking article. For example, at least a portion of the front face of the smoking article lies in a plane (e.g., a generally flat plane) that is positioned about 40 DEG to about 50 DEG relative to the longitudinal axis of that smoking article. As such, the overall nature or character of the mainstream aerosol generated by a smoking article can be altered. This shape may include an ellipse, or may include a first section in a plane not perpendicular to the longitudinal axis and a second section in a plane perpendicular to the longitudinal axis.

Alternatively, the face of the lighting end may have a shape such that its surface area is greater than the cross-sectional area of the smoking article.

Priority:

Inventor: BORSCHKE AUGUST JOSEPH [US]; BROWN BUDDY GENE [US]

Title: Flossing and Oral Hygiene Tool

Applicant/Assignee:

Application No.: 12/239984   Filing Date: 29/Sep/2008

Abstract:

A detachable device for improved dental hygiene supports and tensions dental floss above and beyond the bristles of the tooth brush so that flossing can occur using the bristle end of the tooth brush and avoid having the bristles interfere with the flossing process. In preferred embodiments the device is mechanically coupled to a sonic toothbrush to transmit sonic energy to the floss for improved cleaning. In other embodiments the device includes a tongue cleaning implement.

Priority: US20070978036P Applic. Date: 2007-10-05

Inventor: CULVER KAREN [US]

Title: Oral Care Composition To Reduce Or Eliminate Dental Sensitivity

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/275361   Filing Date: 21/Nov/2008

Abstract:

The invention includes an oral care composition that reduces and/or eliminates the perception of tooth sensitivity. The composition includes an adherent material and particles having an average particle size of about 8 microns or less. The particles are present in the composition in an amount of about 5% by weight. Also included within the scope of the invention are related methods, such as methods of occluding a dentin tubule.

Priority: US2008-103919 Applic. Date: 2008-04-16; US2007-742039 Applic. Date: 2007-04-30

Inventor: ZAIDEL LYNETTE [US]; CHOPRA SUMAN K [US]; PRENCIPE MICHAEL [US]; WANG QIN [US]; CHRISTOPOULOU CONSTANTINA [US]

Title: ACTIVATING BRUSH TIP APPLICATORS FOR DENTAL BLEACHING COMPOSITIONS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/866532   Filing Date: 03/Oct/2007

Abstract:

A brush tipped applicator includes an applicator tip having a body defining an external surface and an internal conduit. The applicator tip body can have a proximal end defining a proximal opening of the internal conduit and a distal end. The proximal end of the applicator tip body can have a first fastener that is configured for being coupled to a fastener (i.e., second fastener) of a member containing the dental bleaching composition such that the internal conduit of the applicator tip body is capable of being fluidly coupled with the dental bleaching composition. Additionally, the brush tip includes at least one filament disposed on the external surface of the applicator tip body. A dental bleach activator disposed within the filament in an amount sufficient for activating the dental bleaching composition for whitening the teeth.

Priority:

Inventor: ALLRED PETER M [US]; VU DAVID Q [US]

Title: DENTAL ENAMEL RECALCIFICATION ACCELERATOR AND CONTAINING THE SAME, ORAL COMPOSITION AND FOOD OR BEVERAGE

Applicant/Assignee: LOTTE CO., LTD

Application No.: 11/914877   Filing Date: 24/May/2005

Abstract:

A dental enamel recalcification accelerator that even when used in oral compositions and food or beverage, poses no safety problem, and that is capable of effectively promoting the recalcification of decalcified dental enamel to thereby positively suppress any dental caries

and containing the same, an oral composition and food or beverage. There is provided a dental enamel recalcification accelerator comprising anhydrogalactose-containing red algae and/or an extract thereof as an active ingredient. Further, there are provided an oral composition and food or beverage comprising the dental enamel recalcification accelerator.

Priority: JP20050147109 Applic. Date: 2005-05-19; WO2005JP09466 Applic. Date: 2005-05-24

Inventor: KOYAMA TAKAAKI [JP]; SUGITA DAIGO [JP]; ASADA SHINYA [JP]; SHIMURA SUSUMU [JP]

Title: Foam Strip for the Delivery of Oral Care Compositions

Applicant/Assignee:

Application No.: 11/918168   Filing Date: 11/Apr/2005

Abstract:

The present invention relates to a polyurethane foam strip (1), shaped for the application to the labile surface of the front teeth and/or gums of a subject, which strip is provided with one or more oral care compositions for delivery to the teeth and/or gums of the subject. It further relates to its use for delivery of compositions, specifically for whitening teeth. It further relates to use of the strip in combination with a dental device.

Priority: WO2005EP03779 Applic. Date: 2005-04-11

Inventor: DE VREESE GUY [BE]; LOMBAERT POL [BE]

Title: POLYMER-METAL CHELATOR CONJUGATES AND USES THEREOF

Applicant/Assignee: UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION

Application No.: 12/243671   Filing Date: 01/Oct/2008

Abstract:

The present invention provides prodrugs comprising a polymer conjugated to a metal chelator via a disulfide bond. For example, D-penicillamine may be conjugated to a polymer (e.g., gelatin, chitosan, polyglutamic acid) via a linker, such as SPDP. Thus, the cellular delivery and pharmacokinetics of D-penicillamine can be substantially improved. Methods for the treatment of cancer using compositions of the present invention are also disclosed.

Priority: US20070978356P Applic. Date: 2007-10-08

Inventor: MUMPER RUSSELL J [US]; GUPTE ANSHUL [US]; WADHWA SAURABH [US]

Title: Anti-corrosion detergent compositions and use of same in cleaning dental and medical instruments

Applicant/Assignee: SCICAN

Application No.: 12/314282   Filing Date: 08/Dec/2008

Abstract:

A novel method for cleaning dental and medical instruments is disclosed, in which a cleaning solution including a low-residue corrosion inhibitor is used not only in a wash stage of the cleaning cycle, but also in at least one subsequent rinse cycle, to optimize both cleaning and rust prevention. A novel cleaning solution particularly suited to this method has a neutral to alkaline pH and comprises in aqueous solution a low-foaming surfactant and a corrosion inhibitor selected from the group of C4-C16 alkyl pyrrolidones and C1-C18 alkylamines.

Priority: US2006-353049 Applic. Date: 2006-02-14; US20050652701P Applic. Date: 2005-02-15

Inventor: TIJANIC VESO [CA]; BHARAJ BHUPINDER [CA]; ACOSTA ZARA EDGAR JOEL [CA]; OMIDBAKHSH NAVID [CA]

Title: DENTAL ADHESIVE AND METHOD OF USE

Applicant/Assignee: KERR CORPORATION

Application No.: 11/868748   Filing Date: 08/Oct/2007

Abstract:

A dental adhesive composition comprising (i) at least one non-acidic polymerizable monomer having at least one ethylenically unsaturated group, (ii) optionally one or more acidic compounds, (iii) at least one photoinitiator, (iv) at least one solvent, and (v) about 0-40% by weight of one or more fillers

wherein the weight ratio of non-acidic polymerizable monomers/acidic compounds in the adhesive composition is more than about 4.5

the viscosity of the adhesive composition is less than about 350 centipoise (cP) at 25 DEG C.

and the adhesive composition excluding solvent and filler has an acid number of less than about 0.75 mmol NaOH/g. The dental adhesive composition is used with a dental primer composition, which may be provided together in a kit.

Priority:

Inventor: QIAN XUEJUN [US]

Title: METHOD OF ENHANCING BEVERAGES BY MEANS OF A UNIQUE MICROENCAPSULATED DELIVERY SYSTEM

Applicant/Assignee:

Application No.: 12/121809   Filing Date: 16/May/2008

Abstract:

The present invention provides a method of imparting flavor enhancers, (flavorings) flavor or aroma masking agents, medicinal additives, fragrances, vitamins, colorants, homeopathic and herbal remedies, appearance and characteristic modifiers and other ingredients to a brewed or steeped beverage such as coffee or tea by means of a microencapsulated delivery system incorporated onto a substrate or filter material such as those used in drip coffee makers or tea bags. The microcapsules are "printed" or laminated to the substrate filter paper in a pattern that allows water to pass through while the microcapsules filled with a flavoring liquid or solid is dissolved thus releasing the contents into the water stream resulting in a flavor-enhanced beverage. Alternative delivery may also be achieved by means of: a) A microcapsule coated paper disc that may simply be immersed in the hot beverage or

b) A microcapsule coated interior wall of a disposable container or cup (A paper coffee cup for example) until such time the hot fluid within the container dissolves the microcapsules thus releasing the latent additive ingredient or a primary formulation of ingredients constituting the entire beverage solution or mixture. Several variations of this technology may be adapted for use with hot, cold or ambient temperature beverage preparation methods. Further aspects of the invention will become apparent from consideration of the drawings and the ensuing description of preferred embodiments of the invention. A person skilled in the art will realize that other embodiments of the invention are possible and that the details of the invention can be modified in a number of respects, all without departing from the inventive concept. Thus, the following drawings, photos and description are to be regarded as illustrative in nature and not restrictive.

Priority: US20070930586P Applic. Date: 2007-05-17

Inventor: CELESTE SALVATORE ALBERT [US]

Title: Smokeless Tobacco Product, Smokeless Tobacco Product in the Form of a Sheet, Extrudable Tobacco Composition, Method for Manufacturing a Smokeless Tobacco Product, Method for Delivering Super Bioavailable Nicotine Contained in Tobacco to a User, and Packaged Smokeless Tobacco Product Sheet

Applicant/Assignee:

Application No.: 12/122201   Filing Date: 16/May/2008

Abstract:

A nonaqueous, extrudable composition includes at least one thermoplastic polymer in an amount of more than 20 wt % of the whole composition and tobacco. A smokeless tobacco product in the form of a sheet can be made by extruding or hot melt shaping a nonaqueous composition comprising at least one thermoplastic polymer and tobacco, the sheet being soluble in a user's mouth and resulting in sustained release of nicotine to the user. The sheet can be in a form that may be placed in the buccal cavity of, on the palate of or sublingually in the user, and have an average dissolution time of 5 to 50 minutes for delivering super bioavailable nicotine to the user.

Priority: US20070979169P Applic. Date: 2007-10-11; US20070990381P Applic. Date: 2007-11-27

Inventor: FUISZ RICHARD C [US]

Title: Container cleaning device, container cleaning method, and tank

Applicant/Assignee:

Application No.: 11/919905   Filing Date: 18/Apr/2006

Abstract:

A cleaning device and a cleaning method for a container capable of continuously performing a cleaning treatment, and a tank. The cleaning device includes a jetting member which jets a fluid in the container

a movement unit which relatively moves the jetting member along an axial direction of the container with respect to the container so that the jetting member is inserted into the container from a mouth part of the container

and a switching unit which switches the jetting member from one function to another function. The switching unit switches a nozzle for a cleaning liquid, a nozzle for blowing and a nozzle for drying in order.

Priority: JP20050140874 Applic. Date: 2005-05-13; JP20050141261 Applic. Date: 2005-05-13; JP20050149777 Applic. Date: 2005-05-23; WO2006JP308491 Applic. Date: 2006-04-18

Inventor: WAKAO YOSHITAKA [JP]; MURATE MASASHI [JP]

Title: HARVESTING CORN COBS

Applicant/Assignee:

Application No.: 12/252104   Filing Date: 15/Oct/2008

Abstract:

A cart is towed behind a combine harvester for collecting corn cobs and includes a conveyer belt feeding into a system for separating cobs from residue to be discharged and a tank for receiving and transporting the cobs. An unload auger is provided from the tank to one side of the cart while the cart moves forward. Power for driving the cart is obtained from a chopper drive of the combine harvester. The separating arrangement includes a series of sequential blower fans for blowing air through the discharged material as it is discharged from a conveyor and into a spreading guide disperses the residue. The cobs are conveyed using a series of augers where the auger to flight distance is at least 2 inches and particularly a pair of augers feed the cobs through a front wall of the tank so as to push cobs upwardly into the tank.

Priority: US20080087409P Applic. Date: 2008-08-08; US20070986438P Applic. Date: 2007-11-08; US20070979988P Applic. Date: 2007-10-15; US20070981134P Applic. Date: 2007-10-19

Inventor: REDEKOP LEO [CA]; MAYERLE DEAN [CA]; WILLEMS SALTON [CA]

Title: APPLIANCE FOR DISPENSING HEATED COSMETIC FLUIDS

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 11/870432   Filing Date: 11/Oct/2007

Abstract:

A device is provided for delivering a heated cosmetic flowable product. The device includes a base with a cavity housing a tube for receiving the flowable product, a heating system heatingly contacting the tube, and an outlet at a downstream end of the tube. A plastic bottle filled with the product is releasably mounted on the base. A fitment is arranged over an open end of the bottle and includes a slitted membrane. An upstream end of the tube penetrates the membrane to establish flowable communication and a sealing relationship. Product is dispensed from the outlet by applying an external squeeze pressure against a wall of the bottle. No mechanical assist is necessary such as a pump or gearing for transporting fluid product.

Priority:

Inventor: DOMOY BRETT CHRISTOPHER [US]

Title: PROTECTIVE ENCLOSURE FOR MODEL VEHICLE

Applicant/Assignee:

Application No.: 11/872872   Filing Date: 16/Oct/2007

Abstract:

The present invention provides for a protective enclosure comprising a base comprising a first continuous mating surface and at least one conveyance aperture, a cover comprising a second continuous mating surface, wherein the second continuous mating surface is configured to form a seal with the first continuous mating surface, and a clamp, wherein at least a portion of the clamp is coupleable to the base, wherein a mouth of the clamp is configured to be offset from the aperture when the clamp is coupled to the base, wherein the clamp comprises a first sealing layer, and wherein the clamp is configured to seal the aperture against contaminants. The protective enclosure may be configured for use in a remotely controllable model vehicle to protect a control module.

Priority:

Inventor: ROBERTS TIMOTHY E [US]; LAMPERT JON KENNETH [US]; ALLMENDINGER OTTO KARL [US]

Title: AIRTIGHT STORAGE BAG

Applicant/Assignee:

Application No.: 11/871563   Filing Date: 12/Oct/2007

Abstract:

An airtight storage bag is defined by at least one plastic film formed into a pouch. The pouch has a containment region with an openable mouth. There are a first resealable zone extending across the openable mouth to allow closure of the month, and a second resealable zone also extending across the mouth and located on the containment region side of the first resealable zone to allow airtight closure of the containment region. A vent is located between the first and second resealable zones to allow displacement of fluid from the containment region via the vent. The second resealable zone when sealed seals the containment region from the exterior of the bag.

Priority:

Inventor: TANG LUEN-SING [HK]

Title: Porous Coating Loaded with a Liquid or a Solid Substance

Applicant/Assignee:

Application No.: 11/991751   Filing Date: 15/Sep/2006

Abstract:

The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps: -providing a support having a surface, -depositing on said surface one mono-layer of temporary particles, -depositing a coating on said temporary particles in such a way that the thickness of said coating is less than the particle diameter, -eliminating said temporary particles and thereby obtaining a porous coating, the pores of said coating corresponding to the spaces previously occupied by the temporary particles and at least a pail of the pores communicating with the external environment, -applying a coating fixation step, characterized by the fact that it furthermore comprise a filling step where said pores are at least partially filled with a liquid or solid substance. The invention also concerns a coating and an object which can be obtained with this process.

Priority: EP20050108573 Applic. Date: 2005-09-16; WO2006IB53323 Applic. Date: 2006-09-15

Inventor: HOFMANN HEINRICH [CH]; NEFTEL FREDERIC [CH]; PIVETEAU LAURENT-DOMINIQUE [CH]

Title: Extrudable and Extruded Compositions for Delivery of Bioactive Agents, Method of Making Same and Method of Using Same

Applicant/Assignee:

Application No.: 12/249456   Filing Date: 10/Oct/2008

Abstract:

A nonaqueous, extrudable composition includes at least one thermoplastic polymer in an amount of more than 20 wt % of the whole composition and tobacco. An extruded bioactive product in the form of a sheet can be made by extruding or hot melt shaping a nonaqueous composition comprising at least one thermoplastic polymer and a bioactive agent, the sheet being soluble in a user's mouth and resulting in sustained release of bioactive to the user. The sheet can be in a form that may be placed in contact with the mucosa of the user, and have an average dissolution time of 5 to 50 minutes for delivering the bioactive to the user.

Priority: US2008-122201 Applic. Date: 2008-05-16; US20070979169P Applic. Date: 2007-10-11; US20070990381P Applic. Date: 2007-11-27; US20080054195P Applic. Date: 2008-05-19

Inventor: FUISZ RICHARD C [US]

Title: Foam-generating, hardening compositions for forming impressions of surfaces and impression trays for use therewith

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 12/062065   Filing Date: 03/Apr/2008

Abstract:

Foam-generating, hardening composition for making impressions of biological surfaces include A at least one impression material based on i isocyanates, which react with mono- and multi-functional amines and/or compounds having hydroxyl groups, to form urethane or urea, or ii A-silicones, or iii C-silicones, or iv Polyethers, or v alpha-silanes, or vi mixtures of two or more materials i to v, and optionally B at least one foaming agent. Impressions of biological surfaces made from this compound have a foam with closed pores.

Priority: DE200710016791 Applic. Date: 2007-04-05

Inventor: KNISPEL GOTTFRIED [DE]; GRUNWALD MARTIN [DE]; GRUNDLER ANDREAS [DE]

Title: Shower head attachment for mixing liquids use to clean teeth

Applicant/Assignee: HEALTH AND HYGIENE INC

Application No.: 11/900763   Filing Date: 15/Oct/2007

Abstract:

A valve for adjusting the flow of water through an oral irrigation device is connected to a shower head by a flexible conduit. The valve is located on a handle connected to a water-dispensing pick for cleaning teeth and gums. Mixing apparatus is provided for injecting a secondary fluid, such as a mouthwash, into the flexible conduit upstream from the pick in a direct stream from the shower head.

Priority:

Inventor: SHAW DANIEL A [US]

Title: Dental tooth extraction implement and method thereof

Applicant/Assignee:

Application No.: 11/974486   Filing Date: 15/Oct/2007

Abstract:

This application relates to the field of Dentistry, and in more particular to the atraumatic extraction of teeth. The instant invention is a wedge-shaped extraction rod to be inserted into a pre-drilled root. With a wider than thick configuration, the wedge-shaped rod allows the controlled introduction of both clockwise and counterclockwise torque around the vertical axis of the root to induce dislodgment from the natural socket seating, before the subsequent vertical removal of the root.

Priority:

Inventor: WEATHERS ARTHUR KITCHINGS [US]

Title: HETEROARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS

Applicant/Assignee:

Application No.: 12/249230   Filing Date: 10/Oct/2008

Abstract:

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070979258P Applic. Date: 2007-10-11

Inventor: JOSHI PRAMOD [US]; KRENITSKY PAUL [US]; TERMIN ANDREAS [US]; WILSON DEAN [US]

Title: MINT AND FLOSS ORAL-PRODUCT CONTAINER

Applicant/Assignee:

Application No.: 12/175677   Filing Date: 18/Jul/2008

Abstract:

An oral-product container is disclosed that includes a plurality of breath fresheners contained therein for breath freshening purposes. The container includes an elongated dental instrument (e.g., a toothpick or dental floss) for hygiene improving purposes contained within the container. In the preferred embodiments, the container has a dispensing opening for dispensing breath fresheners. The container preferably has a laterally movable cover mounted to move between a closed state in which the cover covers both the dispensing opening and the elongated dental instrument and an open state in which the cover exposes both the dispensing opening and the elongated dental instrument.

Priority: US20070950495P Applic. Date: 2007-07-18; US20070950497P Applic. Date: 2007-07-18

Inventor: BERG ROBERT ISAAC [US]; HOELTCEN TOM [CA]

Title: SYSTEM AND AUTOMATIC METHOD FOR EXTRACTION OF GASEOUS ATMOSPHERIC CONTAMINANTS WITH TOXIC PROPERTIES, WHICH ARE RETAINED IN POLYURETHANE FOAM (PUF) FILTERS

Applicant/Assignee:

Application No.: 12/293123   Filing Date: 15/Mar/2007

Abstract:

The present invention provides a system and method for automatic extraction of gaseous atmospheric contaminants (for example HAPs and PCBs) with toxic properties, which are retained in polyurethane foam filters (PUF) that consists of: An automatic extraction device, which allows extracting chemicals compounds of interest using a sequence of organic solvents where the PUF must be immersed in, by means of a process of extraction based on compression and decompression cycles of the PUF

and A drying device which permits to dry the cleaned PUF, from the previous process, by means of sweeping the solvent with hot gaseous ultra pure N2, eliminating the solvent until achieving the dryness of the PUF.

Priority: CL20060000588 Applic. Date: 2006-03-16; WO2007ES70055 Applic. Date: 2007-03-15

Inventor: CERECEDA BALIC FRANCISCO [CL]; CERECEDA BALIC GABRIEL [CL]; DOROCHESI FERNANDOIS MARIO [CL]

Title: STORM DRAIN INLET PROTECTION DEVICE

Applicant/Assignee:

Application No.: 12/257162   Filing Date: 23/Oct/2008

Abstract:

A reusable protection device for a storm drain inlet includes a semi-permeable sleeve filled with a filter media. The protection device generally seats over a mouth to cover the storm drain inlet to allow passage of water runoff, but limit passage of sediment into the storm drain inlet. The sediment can be removed with a cleaning process for the removal of additional sediment from additional runoff water.

Priority: US20070982026P Applic. Date: 2007-10-23

Inventor: LEWIS CLINTON [US]

Title: Denture adhesive compositions with anti-ucler agents

Applicant/Assignee: ORAHEALTH CORPORATION

Application No.: 12/287646   Filing Date: 10/Oct/2008

Abstract:

The present invention relates to methods and compositions for reducing, inhibiting, and/or preventing denture sores, comprising a denture adhesive component and an effective amount of an anti-ulcer agent selected from the group consisting of Glycyrrhiza extract (GX), xylitol, and cobalamin. A denture wearer in need thereof applies the composition to the oral cavity and/or the denture prosthesis at a spot where a denture sore tends to form and thereafter secures the denture to the oral cavity.

Priority: US20070999516P Applic. Date: 2007-10-17

Inventor: HALEY JEFFREY T [US]

Title: FUNCTIONALIZED SUBSTRATES AND METHODS OF MAKING SAME

Applicant/Assignee: PRINCETON UNIVERSITY

Application No.: 12/253462   Filing Date: 17/Oct/2008

Abstract:

Polymer substrates including adhesion layers for activating the surface of the substrate are provided, thereby allowing the substrate to react with organic, inorganic, metallic and/or organometallic materials. The surface of the polymer substrate is coated with a metal oxide layer that is subjected to conditions adequate to form an oxide adhesion layer. Combining deposition techniques for formation of functionalized polymer surfaces with photolithographic techniques enables spatial control of RGD presentation at the polymer surfaces are achieved with sub-cellular resolution. Surface patterning enables control of cell adhesion location at the surface of the polymer and influences cell shape. Metallization of polymers as described herein provides a means to prepare metal-based electrical circuitry on a variety of flexible substrates.

Priority: US20070960859P Applic. Date: 2007-10-17

Inventor: SCHWARTZ JEFFREY [US]; DENNES THOMAS J [US]

Title: STEM CELLS AND LIM MINERALIZATION PROTEINS

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 11/875267   Filing Date: 19/Oct/2007

Abstract:

Methods of changing a phenotype of a cell are provided. The methods comprise increasing an amount of an amino acid sequence which is at least 70% identical to an amino acid sequence encoding an LMP protein or a fragment thereof in a cell. The cells may be contacted by either a composition comprising a nucleic acid sequence encoding the amino acid sequence which is at least 70% identical to the amino acid sequence encoding an LMP or its fragment or by a composition comprising acid sequence which is at least 70% identical to the amino acid sequence encoding an LMP or its fragment or any combination thereof. The cells may be contacted either in vivo or ex-vivo.

Priority:

Inventor: MARX JEFFREY C [US]; MCKAY WILLIAM F [US]; DRAPEAU SUSAN J [US]

Title: Bridged polycyclic compound based compositions for coating oral surfaces in humans

Applicant/Assignee:

Application No.: 12/228263   Filing Date: 11/Aug/2008

Abstract:

A pharmaceutically active agent, a pharmaceutically active agent carrier and method of use thereof are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two pharmaceutically active agents may be associated with the bridged polycyclic compound. In some embodiments, one or more bridged polycyclic compounds may be applied to an oral surface of a human such that an oral malady may be inhibited and/or ameliorated.

Priority: US20070964312P Applic. Date: 2007-08-10; US20070965154P Applic. Date: 2007-08-17; US20080029332P Applic. Date: 2008-02-16; US20080074488P Applic. Date: 2008-06-20

Inventor: WHITEFORD JEFFERY A [US]

Title: PYRIDYL SULFONAMIDES AS MODULATORS OF ION CHANNELS

Applicant/Assignee:

Application No.: 12/212063   Filing Date: 17/Sep/2008

Abstract:

The present invention relates to pyridyl sulfonamide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070994423P Applic. Date: 2007-09-19

Inventor: MARTINBOROUGH ESTHER [US]; ZIMMERMANN NICOLE [US]; NEUBERT TIMOTHY [US]; HAMPTON TARA [US]

Title: FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE

Applicant/Assignee: BEZWADA BIOMEDICAL, LLC

Application No.: 12/212233   Filing Date: 17/Sep/2008

Abstract:

This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.

Priority: US20070975374P Applic. Date: 2007-09-26

Inventor: BEZWADA RAO S [US]

Title: Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same

Applicant/Assignee: KABUSHIKI KAISHA SHOFU

Application No.: 12/225070   Filing Date: 13/Mar/2006

Abstract:

A compound that exhibits excellent color tone stability and physical properties as well as excellent photopolymerization activity over a wide region from near-ultraviolet to visible region, permitting relaxed operation under ambient light, so that wide application can be found in the dental field and photopolymerization industry

and a relevant photopolymerization initiator and hardenable composition. In particular, there is provided a novel camphorquinone derivative having an acylphosphine oxide group [-(C-O)-(P-O)<] in each molecule.

Further, there is provided a photopolymerization initiator comprising the camphorquinone derivative having an acrylphosphine oxide group [-(C-O)-(P-O)<] in each molecule as an indispensable component, loaded with at least one member selected from among a polymerization accelerator, a photoacid generator, a photosensitizer and a (bis)acylphosphine oxide, and provided a hardenable composition comprising the initiator. The thus provided photopolymerization initiator and hardenable composition exhibit excellent color tone stability and physical properties as well as excellent photopolymeritzaion activity over an ultraviolet and visible wide wavelength region, permitting relaxed operation under ambient light, so that wide application can be found in the dental field and photopolymerization industry.

Priority: WO2006JP304911 Applic. Date: 2006-03-13

Inventor: IKEMURA KUNIO [JP]; ICHIZAWA KENSUKE [JP]; JOGETSU YOSHIYUKI [JP]

Title: TIME-CONTROLLED INTRAORAL FILM FORMER SYSTEM FOR INTRAORAL USE

Applicant/Assignee: BISCO, INC

Application No.: 12/254591   Filing Date: 20/Oct/2008

Abstract:

A water soluble polymer or biodegradable polymer operable to act as a release or separator between a prepared and sealed dentin surface and a temporary restoration.

Priority: US20070981392P Applic. Date: 2007-10-19

Inventor: SUH BYOUNG I [US]; LEE JIN WHAN [US]

Title: Materials leading to improved dental composites and dental composites made therefrom

Applicant/Assignee:

Application No.: 11/974772   Filing Date: 16/Oct/2007

Abstract:

Provided herein are uncured dental composites suitable for, among other things, filling cavities in teeth.

Priority: US20060852528P Applic. Date: 2006-10-18

Inventor: ANTON DOUGLAS ROBERT [US]; JAYCOX GARY DELMAR [US]; HUANG YONGQING [US]

Title: SYSTEMS, METHODS AND APPARATUS FOR RESPIRATORY SUPPORT OF A PATIENT

Applicant/Assignee: BREATHE TECHNOLOGIES, INC

Application No.: 11/523519   Filing Date: 20/Sep/2006

Abstract:

Spontaneous respiration is detected by sensors. An additional amount of oxygen is administered to the lungs via a jet gas current at the end of an inhalation procedure. Breathing volume, absorption of oxygen during inhalation, and clearance of carbon dioxide during exhalation are improved. If required, the exhalation procedure of the patient can be arrested or slowed by a countercurrent to avoid a collapse of the respiration paths. An apparatus including an oxygen pump can be connected to an oxygen source and includes a tracheal prosthesis that can be connected via a catheter. The respiration detections sensors are connected to a control unit for activating the oxygen pump. The tracheal prosthesis includes a tubular support body with a connection for the catheter, and the sensors are associated with the support body.

The tracheal prosthesis and jet catheter are dimensioned so the patient can freely breathe and speak without restriction.

Priority: US20050718318P Applic. Date: 2005-09-20

Inventor: FREITAG LUTZ [DE]; KAPUST GREGORY [US]; WONDKA ANTHONY [US]

Title: BLOW MOULDING MACHINE FOR PLASTIC CONTAINERS, AND METHOD FOR CONTROLLING IT

Applicant/Assignee: KRONES AG

Application No.: 12/255986   Filing Date: 22/Oct/2008

Abstract:

The invention relates to an apparatus and method for producing containers. The apparatus comprises at least one heating unit which heats preforms

at least one blow moulding unit which expands heated preforms to form containers

at least one sensor device which outputs at least one measured parameter representative of a physical state of the preforms or containers

wherein at least two control parameters of the heating unit or of the blow moulding unit can be varied

and an adjusting unit which is configured in such a way that it adjusts the control parameters as a function of the measured parameter. According to the invention, the adjusting unit comprises an associating device which associates control parameters with predefined measured parameters in a manner that is freely predefinable.

Priority: DE200710050908 Applic. Date: 2007-10-23; DE200810034934 Applic. Date: 2008-07-26

Inventor: STEINER ANDREAS [DE]

Title: Roller Blind Arrangement With An Improved Guiding System

Applicant/Assignee:

Application No.: 11/994178   Filing Date: 30/Jun/2006

Abstract:

The invention relates to a roller blind arrangement, especially for motor vehicles, for covering a roof opening (2), said arrangement comprising a roller blind strip (5) which can be wound up and down by means of a winding shaft (4). At least one deviating means (10) is used for influencing the course of the roller blind strip (5) in the direction of displacement thereof, the at least one deviating means (10) being arranged at a fixed distance from the winding shaft in the longitudinal direction of the vehicle.

Priority: WO2006DE01138 Applic. Date: 2006-06-30; DE200510030843 Applic. Date: 2005-07-01

Inventor: WINGEN BERNHARD [DE]

Title: LMP and Regulation of Tissue Growth

Applicant/Assignee: WARSAW ORTHOPEDIC, INC

Application No.: 11/924960   Filing Date: 26/Oct/2007

Abstract:

Novel methods are provided for changing cell phenotype, comprising a method of changing a phenotype of a target cell comprising: increasing an amount of an amino acid sequence in a source cell, wherein the source cell is located within a volume of a media and wherein the amino acid sequence is selected from the group consisting of LMP-1 protein, an LMP-2 protein, an LMP-3 protein, an LMP-1s protein, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or combination thereof

collecting at least a portion of the volume of the media

and contacting the target cell with at least the portion of the media.

Priority:

Inventor: MARX JEFFREY C [US]; MCKAY WILLIAM F [US]; DRAPEAU SUSAN J [US]

Title: TRANSMUCOSAL COMPOSITION

Applicant/Assignee:

Application No.: 12/297486   Filing Date: 25/Apr/2007

Abstract:

The invention provides a composition for delivering active agents through transmucosal administration, more particularly through the buccal mucosa. The composition is a unique transmucosal disk (10) which has two compartments (14) and (18)

the compartments consist of at least one active agent and at least one mucoadhesive agent and both the compartments are adapted to be in contact with the mucosal membrane. The invention also provides for transmucosal administration of an active agent and method of treatment of diseases in a subject in need of such treatment.

Priority: IN2006MU00682 Applic. Date: 2006-05-02; WO2007IN00164 Applic. Date: 2007-04-25

Inventor: SINGH AMARJIT [IN]; SINGH SARABJIT [IN]; PUTHLI SHIVANAND [IN]

Title: Methods and Compositions Related to PLUNC Surfactant Polypeptides

Applicant/Assignee:

Application No.: 11/934581   Filing Date: 02/Nov/2007

Abstract:

Embodiments include compositions and methods for lower the surface tension of a liquid-air interface by contacting such interface with all or part of a PLUNC polypeptide.

Priority: US20060864062P Applic. Date: 2006-11-02

Inventor: MCCRAY JR PAUL B [US]; GAKHAR LOKESH [US]; MALLAMPALLI RAMA K [US]; RAMASWAMY SUBRAMANIAN [US]; BARTLETT JENNIFER [US]

Title: FLOTATION AID

Applicant/Assignee:

Application No.: 12/258445   Filing Date: 27/Oct/2008

Abstract:

A flotation aid which has an inflation unit comprising an inflatable bladder and a gas container assembly including a capsule containing a compressed gas for inflating the bladder and having a valve through which gas may be released into the bladder, the gas container assembly being located substantially within the bladder and actuating means actuable externally of the bladder for actuating the valve to allow release of gas from the capsule into the bladder to inflate the bladder. In one form, the inflation unit is housed within a two-part longitudinally split casing, the parts of the casing being interconnected but being separated upon and by inflation of the bladder to release the bladder. In another form, the floatation aid is incorporated in pants or other article of clothing being located in a pocket and secured to the pants or article of clothing.

Priority: AU20070905953 Applic. Date: 2007-10-31

Inventor: HANSON JOHN [AU]

Title: COMPOSITIONS AND METHODS FOR PROMOTING HEMOSTASIS AND OTHER PHYSIOLOGICAL ACTIVITIES

Applicant/Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY VERSITECH LIMITED

Application No.: 12/199670   Filing Date: 27/Aug/2008

Abstract:

Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaiminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.

Priority: US2006-411745 Applic. Date: 2006-04-25; US20050674612P Applic. Date: 2005-04-25; US20060758827P Applic. Date: 2006-01-13

Inventor: ELLIS-BEHNKE RUTLEDGE [US]; ZHANG SHUGUANG [US]; SCHNEIDER GERALD [US]; SO KWOK-FAI [CN]; TAY DAVID [CN]; LIANG YU-XIANG [CN]

Title: Novel 3,9-Diaza-Spiro[5,5]Undecane Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/922931   Filing Date: 28/Jun/2006

Abstract:

This invention relates to novel 3,9-diaza-spiro[5.5]undecane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000960 Applic. Date: 2005-06-28; US20050694678P Applic. Date: 2005-06-29; WO2006EP63631 Applic. Date: 2006-06-28

Inventor: ERIKSEN BIRGITTE L [DK]; PETERS DAN [SE]; NIELSEN ELSEBET OSTERGAARD [DK]; REDROBE JOHN PAUL [DK]

Title: Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof

Applicant/Assignee: OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES

Application No.: 11/886965   Filing Date: 24/Mar/2006

Abstract:

The present invention relates to novel phenyl-N-acyl derivatives of biogenic amines and amino acids of general formula (I) as cyclooxynease inhibitors, possessing analgetic and anti-inflammatory properties and devoid of side effects in particular ulcerogeneity and pro-spasmodic actions, as well as capability to potentiate effect of other analgetics, and possessing in addition antihypoxic, antidepressant and anti-Parkinsonistic action

as well as to the processes for the preparation novel and known phenyl-N-acyl derivatives of biogenic amines, to a pharmaceutical composition and to an agent comprising compounds of general formula (I) as well as to use thereof and a method of treating.

Priority: RU20050108492 Applic. Date: 2005-03-25; WO2006RU00139 Applic. Date: 2006-03-24

Inventor: NEBOLSIN VLADIMIR EVGENIEVICH [RU]; KROMOVA TATYANA ALEXANDROVNA [RU]; ZHELTUKHINA GALINA ALEXANDROVNA [RU]; KOVALEVA VIOLETTA LEONIDOVNA [RU]

Title: MIXING DEVICE INCLUDING A PLUNGING MIXING MEMBER FOR USE WITH A SYRINGE

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 12/258746   Filing Date: 27/Oct/2008

Abstract:

Mixing devices used with a syringe or syringe system and related systems for mixing dissimilar components contained therein. The devices and systems include a hollow elongate handle having a proximal end, a distal delivery end, and a delivery passageway therethrough. A mixing member is disposed at or near the proximal end of the hollow elongate handle, which mixing member and a portion of the handle are axially slidable within a syringe barrel during use. The user may push and pull the distal end of the handle, causing corresponding axial movement of the mixing member within the syringe barrel. The devices and systems may be used to homogenously mix difficult to mix two part compositions, as well as single part compositions which include components that may tend to separate over time (e.g., a fluoride varnish composition).

Priority: US20070984078P Applic. Date: 2007-10-31

Inventor: JESSOP NEIL T [US]

Title: Dental Glass

Applicant/Assignee: IVOCLAR VIVADENT AG EMPA DUEBENDORF EMPA DUBENDORF

Application No.: 12/083821   Filing Date: 25/Sep/2006

Abstract:

The present invention relates to a dental glass containing 50 to 70 wt. % of SiO2, 5 to 18 wt. % of Al2O3, 6.1 to 30 wt. % of MgO, 1 to 15 wt. % of La2O3, 1 to 15 wt. % of WO3, 0.1 to 8 wt. % of ZrO2, and optionally further oxides except for the oxides of Sr, Ba or alkali metals, wherein the stated quantities in total add up to 100 wt. %.

Priority: DE200510051387 Applic. Date: 2005-10-27; WO2006EP66702 Applic. Date: 2006-09-25

Inventor: RITZBERGER CHRISTIAN [AT]; RHEINBERGER VOLKER [LI]; APEL ELKE [CH]; BURTSCHER PETER [AU]; HOLAND WOLFRAM [LI]; GRAULE THOMAS [CH]; ZURCHER SIMONE [CH]; VITAL ANDRI [CH]

Title: Disposable outdoors mask and method of use

Applicant/Assignee:

Application No.: 12/153606   Filing Date: 21/May/2008

Abstract:

A mask designed to be worn to cover the mouth of a user comprises an inner and exterior layers, with an odor adsorbing layer and a filter layer disposed between the inner and exterior layer. The filter layer is positioned between the inner layer and odor adsorbing layer to prevent or minimize entry of unwanted particulate matter into the user's mouth. Once the mask is used to its fullest, it can be thrown away since it is constructed to be sufficiently low in cost so that it can be disposed and another one used the next time odor and particulate filtering is needed.

Priority: US20070984575P Applic. Date: 2007-11-01

Inventor: KIRSCHNER GARRY WILLIAM [CA]

Title: Mouth Seal Assembly for Nasal Mask System

Applicant/Assignee: RESMED LTD

Application No.: 11/988931   Filing Date: 28/Aug/2006

Abstract:

A mouth seal assembly for use with a nasal mask system includes a mouth seal adapted to form a seal with the patient's mouth. The mouth seal is substantially independent from a supply of pressurized air from the nasal mask system. An anti-asphyxia valve may be provided to either the mouth seal over the patient's lips or the nasal mask system. A strap arrangement may support the mouth seal in a desired position on the patient's face in use.

Priority: US20050711669P Applic. Date: 2005-08-29; WO2006AU01246 Applic. Date: 2006-08-28

Inventor: FRATER ROBERT HENRY [AU]; PEAKE GREGORY ROBERT [AU]

Title: Plastic disposable right angle tooth cleaner

Applicant/Assignee:

Application No.: 12/228638   Filing Date: 15/Aug/2008

Abstract:

A molded plastic toothpick device that includes a round handle with a right angle tapered tip. The cylindrical handle allows rotating the device in the finger to correctly insert the taper tip in spaces between both the upper and lower teeth. The objective of the invention is to enable individuals to effectively clean between every tooth easier than dental floss or a straight toothpick. Also you massage the gums between each tooth. This will help keep the gums healthy. It works great in the posterior area. There is no product on the market now that does this. The toothpick can be produced at relatively low cost from plastic.

Priority: US20070969928P Applic. Date: 2007-09-04

Inventor: MCNEIL DON [US]

Title: Grape Polyphenolics for Platelet and Bacterial Control

Applicant/Assignee: SHANBROM TECHNOLOGIES, LLC

Application No.: 11/935926   Filing Date: 06/Nov/2007

Abstract:

Special extracts of grape berries and Gogi berries can be prepared by exposing fruit juices or preparations to an insoluble binding resin which is then extracted with soluble polyvinylpyrollidone. Grape and Goji extracts made in this way can be used to inhibit or control platelet aggregation. Grape extract has exceptional antibacterial properties and can be used to control oral bacteria and to control MRSA (Methicillin-resistant Staphylococcus aureus). The combination of control of platelet aggregation and antibacterial properties exhibited by the grape-extract allows it to be used to significantly extend the life of isolated platelets. When added to solutions of isolated platelets, the grape extract prevents bacterial growth and prevents deterioration of the platelets through activation. This treatment extends the usable life of platelet concentrates to at least ten days.

Priority:

Inventor: SHANBROM EDWARD [US]

Title: Toothpaste composition for tooth whitening

Applicant/Assignee:

Application No.: 11/989283   Filing Date: 13/Jun/2006

Abstract:

The present invention relates to a toothpaste composition having tooth whitening effect, and more specifically, to a toothpaste composition which contains hydrogen peroxide, as peroxide releasing oxygen free radicals for the whitening effect, and silica with reduced contents of metal ions, to overcome the difficulty in long-term storage due to the release of oxygen free radicals resulting from degradation of peroxide by metal ions released from other components in the composition, and unsatisfactory tooth whitening effect. The toothpaste composition of the present invention does not release oxygen free radicals during storage, and so has excellent preservativeness and sustained tooth whitening effect.

Priority: KR20050067140 Applic. Date: 2005-07-25; WO2006KR02257 Applic. Date: 2006-06-13

Inventor: LEE BYUNG-RYEUL [KR]; KANG KYE-HONG [KR]; KIM DAE-KYEONG [KR]; KIM KI-JUNG [KR]

Title: COMPOSITIONS AND METHODS OF USE THEREOF, FOR THE TREATMENT OF ORAL PAIN, COMPRISING CLOVES OR EXTRACTS THEREOF IN COMBINATION WITH A STEROID

Applicant/Assignee:

Application No.: 12/184083   Filing Date: 31/Jul/2008

Abstract:

Provided are compositions for delivery to an individual's mouth to provide immediate as well as long-lasting pain relief, particularly after tooth extraction or other dental procedure, which include clove, a clove extract or eugenol, and optionally a steroid and other additives including an antibiotic. Kits and systems for delivery of the composition to provide sustained pain relief are also provided.

Priority: US20070007512P Applic. Date: 2007-08-03; US20080075724P Applic. Date: 2008-06-25

Inventor: ORONSKY BRYAN T [US]; ORONSKY NEIL C [US]

Title: Furnace assembly

Applicant/Assignee:

Application No.: 12/291357   Filing Date: 07/Nov/2008

Abstract:

The invention relates to a furnace assembly for dental technology, in particular for ceramic dental compositions, comprising a display device associated with a furnace assembly (10), which may be designed in the manner of a touchscreen, and comprising a control device, which has a data interface by way of which data for controlling the furnace assembly and/or image data (in the form of static images or moving images) can be transmitted. The control device has a packet module, in particular an EDGE, GSM, GRPS and/or UMTS module, by way of which control data and/or image data for presentation on the display device can be transmitted in the form of packets.

Priority: DE200710053071 Applic. Date: 2007-11-07

Inventor: GRUNENFELDER ROBERT [LI]

Title: CONCURRENT TREATMENT OF ORAL MALADIES USING DIRECT CURRENT ELECTRICITY

Applicant/Assignee:

Application No.: 12/205062   Filing Date: 05/Sep/2008

Abstract:

A method and apparatus for the concurrent treatment of multiple oral diseases and defects while promoting general oral hygiene utilizing direct current electricity. Electrodes are used to deliver a direct current to the gingival tissues of a mouth in order to achieve a number of therapeutic, prophylactic, and regenerative benefits. These benefits include killing oral microbes, increasing oral vasodilation, improving oral blood circulation, reversing oral bone resorption, promoting oral osteogenesis, treating gum recession, and fostering gingival regeneration. Other benefits include the treatment of gingivitis, perdiodontitis, and oral malodor while also promoting general oral hygiene.

Priority: US2007-850661 Applic. Date: 2007-09-05

Inventor: NEMEH ISSAM [US]; SZATKOWSKI GEORGE NICHOLAS [US]

Title: INTERPROXIMAL MARKING STRAND

Applicant/Assignee:

Application No.: 11/935521   Filing Date: 06/Nov/2007

Abstract:

A method and device for marking a natural tooth/bridge, crown or any dental restoration interface to mark high spots on said bridge or crown to be removed during the fitting process using a fiber or filament strand impregnated or otherwise treated with a visual indicating marker material. The marking device may include the use of handheld tool that includes at least one end having a wishbone shaped support for attaching the fiber or filament strand impregnated with the marker material between the wishbone support or having a tool having both ends with wishbone supports, both ends for supporting one or more filaments or strands of material that includes visual markers.

Priority:

Inventor: RESK RICHARD [US]

Title: Therapeutic Agent for Dentin-Pulp Complex Regeneration

Applicant/Assignee: OSAKA UNIVERSITY KAKEN PHARMACEUTICAL CO., LTD

Application No.: 12/083734   Filing Date: 19/Oct/2006

Abstract:

The present invention provides a therapeutic agent for regenerating a dentin-pulp complex, containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient. The present invention also provides a pulp-capping agent containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient.

Priority: JP20050305076 Applic. Date: 2005-10-19; WO2006JP321308 Applic. Date: 2006-10-19

Inventor: MURAKAMI SHINYA [JP]; SHIMABUKURO YOSHIO [JP]

Title: THIAZOLOPYRIMIDINE P13K INHIBITOR COMPOUNDS AND METHODS OF USE

Applicant/Assignee: GENENTECH, INC F. HOFFMANN - LA ROCHE AG

Application No.: 12/236317   Filing Date: 23/Sep/2008

Abstract:

Compounds of Formulas Ia and Ib, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20070974708P Applic. Date: 2007-09-24

Inventor: CASTANEDO GEORGETTE M [US]; GUNZNER JANET L [US]; MALESKY KIMBERLY [US]; MATHIEU SIMON [US]; OLIVERO ALAN G [US]; SUTHERLIN DANIEL P [US]; WANG SHUMEI [US]; ZHU BING-YAN [US]; CHUCKOWREE IRINA [GB]; FOLKES ADRIAN [GB]; OXENFORD SALLY [GB]; WAN NAN CHI [GB]

Title: THIENOPYRIMIDINES, THIENOPYRIDINES, AND PYRROLOPYRIMIDINES AS B-RAF INHIBITORS

Applicant/Assignee: WYETH

Application No.: 12/262622   Filing Date: 31/Oct/2008

Abstract:

The present invention relates to compounds of formula la: and pharmaceutically acceptable salts thereof. The thieno[3,2-d]pyrimidine, thieno[2,3-d]pyrimidine, thieno[3,2-b]pyridine, thieno[2,3-b]pyridine, and pyrrolo[2,3-d]pyrimidine compounds selectively inhibit B-Raf kinase activity and are useful for treating disorders mediated by B-Raf kinase, and for the treatment of cancer.

Priority: US20070984918P Applic. Date: 2007-11-02

Inventor: GOPALSAMY ARIAMALA [US]; SHI MENGXIAO [US]; BERGER DAN MAARTEN [US]; DUTIA MINU DHANJISHA [US]; TORRES NANCY [US]; HOPPER DARRIN WILLIAM [US]

Title: Hardenable dental compositions with low polymerization shrinkage

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/912950   Filing Date: 09/May/2006

Abstract:

The present invention features a hardenable dental composition that contains: (1) at least one cyclic allylic compound having at least one sulfur atom in the ring, and (2) at least one at least one ethylenically unsaturated compound, such as a substituted (meth)acryloyl compound. The compositions also typically comprise an initiator system, preferably a photoinitator system containing at least 0.08 wt-% of one or more photosensitizers.

Priority: US20050679265P Applic. Date: 2005-05-09; WO2006US17820 Applic. Date: 2006-05-09

Inventor: ABUELYAMAN AHMED S [US]; MITRA SUMITA B [US]; LEWANDOWSKI KEVIN M [US]; PLAUT DAVID J [US]; JONES TODD D [US]

Title: Electric vacuum head

Applicant/Assignee:

Application No.: 12/288260   Filing Date: 17/Oct/2008

Abstract:

An electric vacuum head for a vacuum cleaner has a housing, a cleaning device that can be driven by an electric motor disposed within the housing in a motor chamber, a vacuum mouth on the underside of the housing delimited by vacuum mouth edges, and a vacuum connector. The motor chamber has at least one air entry opening for entry of air to cool the electric motor, and at least one air exit opening. The air exit opening is disposed on the underside of the housing so that the cooling air that exits from the air exit opening during operation of the electric vacuum head enters into the vacuum mouth by way of at least one of the vacuum mouth edges.

Priority: EP20070022070 Applic. Date: 2007-11-14

Inventor: DILGER HORST [DE]; KAFFENBERGER DIETER [DE]; LIND THOMAS [DE]; RIEHL KLAUS-DIETER [DE]; STEUDTNER HANS-JOACHIM [DE]

Title: Insulation stripping tool with displaceable knife carrier means

Applicant/Assignee: WEIDMUELLER INTERFACE GMBH & CO. KG

Application No.: 12/290558   Filing Date: 31/Oct/2008

Abstract:

A pliers-type insulation stripping tool includes a pair of blade holders that are removably connected with the pull rod that longitudinally displaces the blades relative to the handle shell when a severed length of insulation is stripped from the insulated conductor. A resilient ejector arrangement in provided for ejecting from the handle shell the length of stripped insulation. In order to permit use of the insulation stripping tool with insulated conductors of various sizes and diameters, a blade depth adjusting device is provided for adjusting the distance between at least one of the blade holders and the associated clamping jaw.

Priority: DE200720015348U Applic. Date: 2007-11-02

Inventor: STORM SIEGFRIED [DE]; HEGGEMANN CHRISTIAN [DE]; HETLAND DETLEV [DE]; HANNING GUENTER [DE]; KOESTER THOMAS [DE]; WEDLER ANDREAS [DE]

Title: Multi-Ribbed Dental Tape

Applicant/Assignee:

Application No.: 12/184067   Filing Date: 31/Jul/2008

Abstract:

The present invention includes monofilament dental tapes for removing plaque and/or food debris from interdental spaces of a mammal, which dental tapes have a core body with an aspect ratio of greater than about 5:1 and a first cleaning surface and a second cleaning surface opposite the first cleaning surface, where at least one of the first and second cleaning surfaces includes a plurality of ribs disposed along the length thereof, and where the ratio of the width of the dental tape to the thickness of the dental tape is from about 4:1 to about 25:1.

Priority: US2007-937025 Applic. Date: 2007-11-08

Inventor: OCHS HAROLD D [US]; KNUTZEN JOSEF V [US]; FOUGERE RICHARD J [US]; LEBOVSKY ALEXANDER [US]

Title: Multi-Ribbed Dental Tape

Applicant/Assignee:

Application No.: 11/937025   Filing Date: 08/Nov/2007

Abstract:

The present invention includes monofilament dental tapes for removing plaque and/or food debris from interdental spaces of a mammal, which dental tapes have a core body with an aspect ratio of greater than about 5:1 and a first cleaning surface and a second cleaning surface opposite the first cleaning surface, where at least one of the first and second cleaning surfaces includes a plurality of ribs disposed along the length thereof, and where the ratio of the width of the dental tape to the thickness of the dental tape is from about 4:1 to about 25:1.

Priority:

Inventor: OCHS HAROLD D [US]; KNUTZEN JOSEF V [US]; FOUGERE RICHARD J [US]; LOBOVSKY ALEXANDER [US]

Title: Temporary Facial Decal

Applicant/Assignee:

Application No.: 11/938698   Filing Date: 12/Nov/2007

Abstract:

A temporary facial decal comprising a mask-like substrate having apertures for the eyes and mouth and having a nose opening taken from the group of slit and aperture with the body of the mask having a transferable image thereon covered by a removable protective sheet that is removed from the decal which is then placed on the user's face using the provided apertures for alignment whereupon an agent, preferably water, is used to transfer the image onto the user's face.

Priority:

Inventor: MARSHALL DOUGLAS [US]

Title: Sanitary toothbrush holder

Applicant/Assignee:

Application No.: 11/983378   Filing Date: 08/Nov/2007

Abstract:

A toothbrush holder and sterilizer having a cylindrical body with an interior shoulder adjacent the upper end and a perforated bottom wall with an annular flange extending downwardly relative to the body. A fluid reservoir upstanding from the bottom wall, the reservoir being open at the top and having a plurality of annularly spaced openings spaced downwardly of the upper end of the reservoir. There is also an exterior shoulder adjacent the upper end of the reservoir in the same plane as the shoulder at the upper end of the body to support an annular disk having a plurality of spaced openings for reception of toothbrushes. A shallow cup is disposed on the flange on the bottom of the body for reception of condensed disinfectant or the like which will flow through the openings or perforations in the bottom wall. Any suitable disinfectant, antiseptic, germicide or the like in liquid form, is disposed in the reservoir and the fumes from the disinfectant pass upwardly and out of the upper end of the reservoir into the chamber where the bristled ends of the toothbrushes are disposed.

Priority:

Inventor: MILLER DENNIS BEACH [US]

Title: CONTAINER HAVING DELIVERY MECHANISM WITH SECURING CAP

Applicant/Assignee: PIBED LIMITED

Application No.: 12/357181   Filing Date: 21/Jan/2009

Abstract:

A container having a mechanism that delivers liquid from a container to a mouth and that moves between an extended position and a depressed position to deliver the contents of the container to the mouth and a removable securing cap that retains the mechanism in the depressed position.

Priority: US2007-981895 Applic. Date: 2007-11-01

Inventor: LIMBERT DEAN PHILIP [GB]

Title: DENTAL CLEANSER AND STAIN PREVENTION APPARATUS

Applicant/Assignee:

Application No.: 11/938167   Filing Date: 09/Nov/2007

Abstract:

Several embodiments of a dental cleanser and stain prevention apparatus for portable use are described. In each embodiment an apparatus for use in on-the-go dental cleansing is described. In one series of embodiments, disposable dental cleaning devices are described. In another series of embodiments, reusable and refillable dental cleaning devices are described. Packaging of various types is also disclosed for use in housing the dental cleanser and stain prevention apparatus.

Priority:

Inventor: ROSS KAREN L [US]

Title: Multiphase Toothpaste Composition

Applicant/Assignee:

Application No.: 11/883751   Filing Date: 12/Jan/2006

Abstract:

Multiphase toothpaste composition comprising a first phase disposed co-axially within a second, visually clear gel phase, the second phase comprising from 1 ppm to 100 ppm of a pigment.

Priority: IN2005MU00118 Applic. Date: 2005-02-04; IN2005KO00288 Applic. Date: 2005-04-08; WO2006EP00256 Applic. Date: 2006-01-12

Inventor: BIJLANI NAND SANMUKHDAS [IN]

Title: Flavour Compositions

Applicant/Assignee:

Application No.: 12/330624   Filing Date: 09/Dec/2008

Abstract:

Flavor compositions which reduce or prevent dental cavities based on the use of flavor materials found to inhibit the production of acid by micro-organisms in the oral cavity, e.g. lactic acid production from glucose by Streptococcus mutans. The compositions include at least two flavor materials from group (a) and at least one flavor material from group (b). Representative group (a) flavors are decanol, nonanol and cinnamic aldehyde while typical group (b) flavors are nonanal, citral and peppermint oil of material origin.

Priority: GB20030003676 Applic. Date: 2003-02-18; US2005-545746 Applic. Date: 2005-08-17; WO2004GB00515 Applic. Date: 2004-02-11

Inventor: BEHAN JOHN MARTIN [GB]; BRADSHAW DAVID JONATHAN [GB]; RICHARDS JONATHAN [GB]; MUNROE MICHAEL JOHN [GB]

Title: Anti-sensitivity,anti-caries, anti-staining, anti-plaque ultra-mild oral hygiene agent

Applicant/Assignee: RHODIA INC

Application No.: 12/319856   Filing Date: 13/Jan/2009

Abstract:

This invention relates to a composition useful as a dentifrice comprising a surfactant agent consisting essentially of monoalkyl and dialkyl phosphate esters, wherein the ratio of monoesters to diesters is greater than 1, and optionally an abrasive agent consisting essentially of siliceous materials.

Priority: US2004-783721 Applic. Date: 2004-02-20; US20030449128P Applic. Date: 2003-02-21

Inventor: REIERSON ROBERT LEE [US]; DOMKE TODD WILLIAM [US]

Title: Method for the potentiation of opioid analgesics effects on pain

Applicant/Assignee: LAY LINE GENOMICS S.P.A

Application No.: 11/921266   Filing Date: 23/Jun/2006

Abstract:

According to the invention there is provided use of an anti-TrkA antibody capable of inhibiting the binding between NGF and TrkA combined with at least one opioid analgesic for the preparation of a medicament for treating and/or preventing pain.

Priority: IT2005RM00332 Applic. Date: 2005-06-24; WO2006IT00488 Applic. Date: 2006-06-23

Inventor: PAVONE FLAMINIA [IT]; MARINELLI SARA [IT]; CATTANEO ANTONINO [IT]; UGOLINI GABRIELE [IT]

Title: Food dicer

Applicant/Assignee:

Application No.: 11/921412   Filing Date: 06/Jun/2006

Abstract:

A dicing tool having: a foodstuff holder for holding a block of foodstuff and a cutting base

the cutting base having: a rectangular framework for sliding the foodstuff holder therealong

a first part having an triangular shaped front edge, equally spaced triangular cutting blades being arranged in a triangular arrangement that follows the profile of the triangularly shaped front edge

a handle

a second part having a second upper surface and a right front edge and a left front edge arranged in a deep V shape, with continuous blades attached to the right and left front edges

wherein the second upper surface is always parallel to the first surface and can be slidingly reciprocated between an upper position and a lower position where the horizontal blade is substantially on a level with the first surface and the base of the triangular cutting blades.

Priority: US20050688720P Applic. Date: 2005-06-09; WO2006IL00652 Applic. Date: 2006-06-06

Inventor: TWEG EDWARD [IL]

Title: SUBSTRATE HAVING AN ELECTRON DONATING SURFACE WITH METAL PARTICLES COMPRISING PALLADIUM ON SAID SURFACE

Applicant/Assignee: BACTIGUARD AB

Application No.: 12/296429   Filing Date: 05/Apr/2007

Abstract:

There is disclosed a substrate with an electron donating surface, characterized in having metal particles on said surface, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, and platinum, wherein the amount of said metal particles is from about 0.001 to about 8 mug/cm2. Examples of coated objects include contact lenses, pacemakers, pacemaker electrodes, stents, dental implants, rupture nets, rupture mesh, blood centrifuge equipment, surgical instruments, gloves, blood bags, artificial heart valves, central venous catheters, peripheral venous catheters, vascular ports, haemodialysis equipment, peritoneal dialysis equipment, plasmapheresis devices, inhalation drug delivery devices, vascular grafts, arterial grafts, cardiac assist devices, wound dressings, intermittent catheters, ECG electrodes, peripheral stents, bone replacing implants, orthopaedic implants, orthopaedic devices, tissue replacing implants, intraocular lenses, sutures, needles, drug delivery devices, endotracheal tubes, shunts, drains, suction devices, hearing aid devices, urethral medical devices, and artificial blood vessels.

Priority: US20060790307P Applic. Date: 2006-04-07; WO2007SE50226 Applic. Date: 2007-04-05

Inventor: OHRLANDER MATTIAS [SE]; SODERVALL BILLY [SE]

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 12/082365   Filing Date: 09/Apr/2008

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2007-706088 Applic. Date: 2007-02-13; US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]

Title: Peptides Exhibiting Efficacies of Improvement in Skin Conditions or Treatment of Periodental Diseases

Applicant/Assignee:

Application No.: 12/083970   Filing Date: 24/Oct/2006

Abstract:

The present invention relates to a composition for improving a skin condition or treating a periodontal disease, which comprises as an active ingredient a basic fibroblast growth factor-derived peptide. The peptides of this invention exhibit superior efficacies and much better stability and skin permeation than natural-occurring bFGF. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on improvement in skin conditions and treatment of periodontal diseases. In addition, the peptides of this invention can be advantageously applied to pharmaceutical compositions, cosmetics, tooth-paste and compositions for mouth cleaning and caring.

Priority: KR20050100391 Applic. Date: 2005-10-24; WO2006KR04350 Applic. Date: 2006-10-24

Inventor: CHUNG YONG JI [KR]; KIM YOUNG DEUG [KR]; KIM CHUNG RYUL [KR]

Title: HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS

Applicant/Assignee:

Application No.: 12/269109   Filing Date: 12/Nov/2008

Abstract:

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070987490P Applic. Date: 2007-11-13

Inventor: STAMOS DEAN [US]; MARTINBOROUGH ESTHER [US]; ZIMMERMANN NICOLE [US]; NEUBERT TIMOTHY [US]; NUMA MEHDI MICHEL DJAMEL [US]; WHITNEY TARA [US]; HAMPTON TARA LEANNE [US]

Title: Novel n-phenyl-piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/921771   Filing Date: 07/Jun/2006

Abstract:

This invention relates to novel N-phenyl-piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000836 Applic. Date: 2005-06-08; US20050688381P Applic. Date: 2005-06-08; WO2006EP62951 Applic. Date: 2006-06-07

Inventor: PETERS DAN [SE]; REDROBE JOHN PAUL [DK]; NIELSEN ELSEBET OSTERGAARD [DE]; BROWN DAVID TRISTAM [DK]

Title: TRPV1 ANTAGONISTS

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/256931   Filing Date: 23/Oct/2008

Abstract:

Compounds of formula (I) wherein R1, R2, R4, and W are defined in the description are TRPV 1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20070982490P Applic. Date: 2007-10-25

Inventor: PERNER RICHARD J [US]; KOENIG JOHN R [US]; DIDOMENICO JR STANLEY [US]; BAYBURT EROL K [US]; DAANEN JEROME F [US]; GOMTSYAN ARTHUR [US]; KORT MICHAEL E [US]; KYM PHILIP R [US]; SCHMIDT ROBERT G [US]; VASUDEVAN ANIL [US]; VOIGHT ERIC [US]

Title: TRPV1 ANTAGONISTS

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 12/256924   Filing Date: 23/Oct/2008

Abstract:

The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4, R5, m, and n are defined in the specification are TRPV1 antagonists. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20070982200P Applic. Date: 2007-10-24

Inventor: GOMTSYAN ARTHUR R [US]; SCHMIDT ROBERT G [US]; BAYBURT EROL K [US]; DAANEN JEROME F [US]; KORT MICHAEL E [US]

Title: USE OF ALKAMIDES FOR MASKING AN UNPLEASANT FLAVOR

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 12/266209   Filing Date: 06/Nov/2008

Abstract:

An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine

cis-pellitorine

2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide

2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide

2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide)

2E,4Z-decadienoic acid-N-(2-methylbutyl)amide

achilleamide

sarmentine

2E- or 3E-decenoic acid-N-isobutylamide

3E-nonenoic acid-N-isobutylamide

spilanthol

homospilanthol

2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide

2E- or 2Z-decen-4-oic acid-N-isobutylamide

alpha-sanshool

alpha-hydroxysanshool

gamma-hydroxysanshool

gamma-hydroxysanshool

gamma-hydroxyisosanshool

gamma-dehydrosanshool

gamma-sanshool

bungeanool

isobungeanool

dihydrobungeanool

or tetrahydrobungeanool, or combinations thereof.

Priority: US20070986343P Applic. Date: 2007-11-08

Inventor: LANGER KATHRIN [DE]; LEY JAKOB [DE]; REINDERS GERALD [DE]; KINDEL GUNTER [DE]; KRAMMER GERHARD [DE]

Title: DENTAL TOOL CLEANER

Applicant/Assignee:

Application No.: 12/270681   Filing Date: 13/Nov/2008

Abstract:

A flexibly resilient porous body for cleaning dental tools is positioned in a receptacle. The receptacle may be conveniently held near a patient's mouth. The porous body includes surface grooves or cuts and is impregnated with an antibacterial solution. A dental tool which has been used to scrape the area around a patient's teeth and gums may be passed through the surface groove or cut in the porous body to remove any material and disinfect the tip of the dental tool.

Priority: US20070988480P Applic. Date: 2007-11-16

Inventor: WHIPPLE AMY A [US]; VOGL DANIEL J [US]

Title: Insulation stripping tool with striker means

Applicant/Assignee:

Application No.: 12/290479   Filing Date: 31/Oct/2008

Abstract:

An insulation stripping tool of the pliers-type includes an adjustable pull rod stop device for limiting the extent of travel of the longitudinally displaceable pull rod and the cutting and stripping blades connected thereto, thereby to produce only partial removal of a length of severed insulation layer from an insulated conductor. An adjustable conductor stop device is mounted on at least one of the cutting and stripping blade holders for limiting the extent to which the end of the insulated conductor is inserted into the open mouth of the stripping tool. A stationary scale is mounted on one of the handles adjacent the adjustable conductor stop device.

Priority: DE200720015347U Applic. Date: 2007-11-02

Inventor: STORM SIEGFRIED [DE]; HEGGEMANN CHRISTIAN [DE]; HETLAND DETLEV [DE]; HANNING GUENTER [DE]; KOESTER THOMAS [DE]; WEDLER ANDREAS [DE]

Title: Tongue grasping and restraining apparatus and methods

Applicant/Assignee:

Application No.: 11/986044   Filing Date: 17/Nov/2007

Abstract:

A tongue grasping and restraining device holds the tongue securely during sleep in order to minimize the risk of the tongue slipping back and blocking the throat, a condition known as obstructive sleep apnea. Plural tongue gripping projections are coupled to upper and lower supports. The projections engage and hold the tongue. The upper and lower supports are biased toward one another into a tongue engaging position. The upper support is coupled to the user's upper jaw, for example, to a denture, dental appliance or by upper teeth engaging mechanisms. The lower support can be hinged or otherwise joined to the upper support or can be separate therefrom. A tube and rod mechanism in one embodiment couples the upper and lower supports together. Exemplary methods of manufacturing tongue gripping projections are also disclosed.

Priority:

Inventor: SUMMER JOHN DAVID [US]

Title: Plural Activating Optical Change Toothpastes, Stimuli and Elements

Applicant/Assignee:

Application No.: 11/629113   Filing Date: 10/Jun/2005

Abstract:

Optical change toothpaste compositions (as well as methods for making and using the same), and methods for inducing and stimulating optical changes and associated elements for imparting optical changes are provided. Optical change toothpastes can possess a plurality of visual and reporting properties and find use in a variety of different applications.

Priority: US20040579060P Applic. Date: 2004-06-10; WO2005US20702 Applic. Date: 2005-06-10

Inventor: RIBI HANS O [US]

Title: Diamond, precious and semi-precious dust polishing agent for dental veneers and teeth

Applicant/Assignee:

Application No.: 12/288708   Filing Date: 22/Oct/2008

Abstract:

A diamond dust polishing agent for home use and professional use in the care of natural tooth enamel and dental veneers comprised of a quantity of diamond dust coated with a lubricant in conjunction with a paste for carrying the lubricant coated diamond dust, or other semi-precious, non-toxic abrasive dust, said diamond dust being of a size of approximately 500 nanometers or less to a size of approximately 5 nanometers. The size of the dust of both the diamond and the semi-precious stone may vary, depending on the degree of abrasiveness and the lubricant employed. The diamond dust (and semi-precious dust) polishing agent permits the user to maintain the polish and luster of the natural tooth enamel and veneer at home without adversely abrading or damaging the surface thereof.

Priority: US20070003552P Applic. Date: 2007-11-16

Inventor: HERMAN MICHAEL [US]

Title: DENTAL APPLIANCE CLEANSER

Applicant/Assignee:

Application No.: 12/293980   Filing Date: 22/Mar/2007

Abstract:

This invention relates to a dental appliance cleanser which is a metastable emulsion comprising about 50-99% w/w of an aqueous phase, about 1-50% w/w of a water immiscible oily phase, the oily phase having a combination of a one or more immiscible oils and one or more flavor oils. The dental appliance cleanser is applied to the dental appliance, outside the wearer's mouth, in the form of an aerated foam.

Priority: US20060785313P Applic. Date: 2006-03-23; WO2007US64596 Applic. Date: 2007-03-22

Inventor: BROGDEN KYLE N [US]; LECH STANLEY J [US]; MEHTA NARCSH I [US]; OTHS PHILIP J [US]

Title: Topical Composition for Treating Pain

Applicant/Assignee:

Application No.: 11/942409   Filing Date: 19/Nov/2007

Abstract:

Topical compositions having as the active ingredient a hydrophilic material, such as a polyalkylene oxide homopolymer or copolymer, and methods of use, have been developed for the amelioration or prevention of pain or the sequelae of pain. The composition may be in the form of a cream, gel, lotion, spray, foam, paste, patch, suspension or dispersion. In the preferred embodiment, the formulation is a gel. The composition may contain a penetration enhancer, most preferably one with membrane disruptive properties. In one embodiment, the compositions are incorporated onto or into disposables such as hemorrhoid wipes, gauze, sponge, bandages, and wraps

mouth guards, dental trays

needles or catheters

adult diapers

gloves, socks or wrist bands, for ease of application. The composition is applied topically to a site at or adjacent to a painful region. The composition is reapplied as necessary. Pain relief is typically obtained within minutes and lasts for periods of variable duration ranging from minutes to several hours and even, in some cases, days. The composition is variably effective to treat visceral, somatic and neuropathic pain both acute and chronic as well as muscle pain and stiffness and joint pain and stiffness.

Priority:

Inventor: ORONSKY BRYAN TODD [US]; ORONSKY NEIL CHARLES [US]; ORONSKY ARNOLD L [US]

Title: Oral Tissue Regeneration and Repair

Applicant/Assignee:

Application No.: 12/282326   Filing Date: 05/Mar/2007

Abstract:

A method for treating an oral condition of a subject by grafting cultured tissue constructs to the oral tissue. The cultured tissue constructs comprise cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention comprise cells derived from human tissue.

Priority: US20060779050P Applic. Date: 2006-03-03; WO2007US63301 Applic. Date: 2007-03-05

Inventor: EKLUND DARIO C [US]

Title: Compositions and methods for use for antibodies against sclerostin

Applicant/Assignee:

Application No.: 12/249050   Filing Date: 10/Oct/2008

Abstract:

The present invention relates to antibodies against sclerostin and compositions and methods of use for said antibodies to treat disease related to bone abnormalities such as osteoporosis. An embodiment of the invention herein provides an antibody or a functional protein comprising an antigen-binding portion of said antibody for a target in sclerostin polypeptide, characterized in that the antibody or functional protein specifically binds to sclerostin polypeptide and can increase at least one of bone formation, bone mineral density, bone mineral content, bone mass, bone quality and bone strength in a mammal.

Priority: EP20070118414 Applic. Date: 2007-10-12; EP20080151911 Applic. Date: 2008-02-25; EP20080161342 Applic. Date: 2008-07-29

Inventor: KNEISSEL MICHAELA [CH]; HALLEUX CHRISTINE [CH]; HU SHOU-IH [US]; DIEFENBACH-STREIBER BEATE [DE]; PRASSLER JOSEF [DE]

Title: Method for altering hematopoietic progenitor cell adhesion, differentiation, and migration

Applicant/Assignee:

Application No.: 10/573944   Filing Date: 28/Sep/2004

Abstract:

The present invention satisfies the need in the art by providing methods for altering hematopoietic progenitor cell adhesion and/or migration to a target tissue, and for altering hematopoietic progenitor cell differentiation into a second cell type. The invention also provides methods for screening test compounds for altering the level of hematopoietic progenitor cell adhesion and/or migration to a target tissue, and for altering hematopoietic progenitor cell differentiation into a second cell type. The invention further provides methods for isolating hematopoietic progenitor cells.

Priority: US20030507202P Applic. Date: 2003-09-29; WO2004US31825 Applic. Date: 2004-09-28

Inventor: VARNER JUDITH A [US]

Title: Biologically Active Nanoparticles A Carbonate-Substituted Hydroxyapatite, Process For Their Preparation And Compositions Incorporating The Same

Applicant/Assignee:

Application No.: 11/916022   Filing Date: 30/May/2006

Abstract:

The invention relates to biologically active nanoparticles of a carbonate-substituted non-stoichiometric hydroxyapatite, having: a) a crystallinity degree CD lower than 40%, the crystallinity degree being defined as CD=(1-X/Y).100 wherein: Y=height of the diffraction maximum at 2theta=33 DEG , X=height of the diffraction background at 2theta=33 DEG of the nanoparticles X-ray diffraction pattern

b) a length L ranging from 20 to 200 nm and a width W ranging from 5 to 30 nm

and c) an aspect ratio AR comprised between 2 and 40, the aspect ratio being defined as AR=L/W. The biologically active nanoparticles of the invention find a preferred use in oral or dental hygiene applications and may be formulated as compositions for oral or dental hygiene such as, for example, solutions, suspensions, oils, gels or other solid products. Other aspects of the invention include a process for preparing a suspension for oral or dental hygiene including the aforementioned biologically active nanoparticles, a process for manufacturing a toothpaste comprising the nanoparticles, as well as a method of locally remineralizing the teeth comprising contacting the teeth with the nanoparticles.

Priority: WO2006EP05146 Applic. Date: 2006-05-30

Inventor: GAZZANIGA GIANCARLO [IT]; ROVERI NORBERTO [IT]; RIMONDINI LIA [IT]; PALAZZO BARBARA [IT]; IAFISCO MICHELE [IT]; GUALANDI PAOLO [IT]

Title: STERILIZING COMPOSITIONS COMPRISING PHOSPHORS FOR CONVERTING ELECTROMAGNETIC RADIATION TO UVC RADIATION AND METHODS FOR USING THE SAME

Applicant/Assignee:

Application No.: 12/269900   Filing Date: 13/Nov/2008

Abstract:

There is disclosed a composition for converting electromagnetic energy to ultraviolet C (UVC) radiation or radiation of a shorter wavelength, the composition comprising at least one phosphor capable of converting an initial electromagnetic energy (A) to an electromagnetic energy (B) comprising UVC radiation or radiation of a shorter wavelength, and an organic or inorganic media containing said phosphor. There is also a method of sterilizing an article by exposing it to UVC radiation or radiation of a shorter wavelength for a time sufficient to deactivate or kill at least one microorganism and/or for a time sufficient to inhibit abnormal cell growth within the body, when said composition is in an implantable medical device. A method of coating an article with such compositions is also disclosed.

Priority: US20070988466P Applic. Date: 2007-11-16

Inventor: BERNSTEIN ERIC F [US]

Title: DENTAL IMPLANT AND PRODUCTION METHOD FOR SAID IMPLANT

Applicant/Assignee: THOMMEN MEDICAL AG

Application No.: 12/091925   Filing Date: 17/Oct/2006

Abstract:

The invention relates to a dental implant, which comprises a coating at least in those surface areas that come into contact with hard and/or soft tissue when implanted. To ensure that the active ingredient contained in the coating (bisphosphonate) is released into the surrounding tissue or can act in the latter in a controlled manner at the correct speed, the coating is characterised in that it contains bisphosphonate, the respective pharmaceutically compatible salts or esters of the latter, in addition to at least one amphiphilic component, selected from the group containing branched or linear, substituted or unsubstituted, saturated or partially unsaturated C10-C30 alkyl-, alkenyl, alkylaryl-, aryl-, cycloalkyl-, alkylcycloalkyl-, alkylcycloaryl-carboxylates, -phosphates or -sulfates or mixtures thereof and/or a water-soluble ionic polymer component. The invention also relates to a method for producing a dental implant of this type and to a specific composition, which can be used to produce a coating of this type.

Priority: CH20050001723 Applic. Date: 2005-10-27; WO2006CH00577 Applic. Date: 2006-10-17

Inventor: SCHLOTTIG FALKO [CH]; SCHNABELRAUCH MATTHIAS [DE]; KAUTZ ARMIN REX [DE]

Title: FORMULATION FOR DECREASING TOBACCO, ALCOHOL, DRUG OR FOOD CONSUMPTION

Applicant/Assignee: XVASIVE, INC

Application No.: 11/942414   Filing Date: 19/Nov/2007

Abstract:

Formulations have been developed which assist individuals having an addiction such as smoking to reduce or quit engaging in the addictive behavior. Representative behaviors include smoking, excessive alcohol or food ingestion, drug addiction, and ingestion of caffeine or junk food providing quick "highs". The formulations assist the smoker to become dissatisfied with smoking, until he or she willingly gives up the habit or at least cuts down on the number of cigarettes smoked per day as an initial step towards quitting in the future. The formulations can also be used in conjunction with other known formulations, such as nicotine gum or patch. The formulations contain hydrophilic polymers, for example, polyethylene glycol (PEG) alone or in combination or polyvinyl pyrrolidone (PVP) (also known as povidone or polyvidone alone or in combination.), sweeteners and/or flavorings, viscosity modifiers/binders, and pH or buffering agents.

Priority:

Inventor: ORONSKY BRYAN T [US]; ORONSKY NEIL C [US]; ORONSKY ARNOLD L [US]

Title: Diamond dust polishing cloth for natural tooth enamel and dental veneers

Applicant/Assignee:

Application No.: 12/288644   Filing Date: 22/Oct/2008

Abstract:

A disposable tooth cleaning article for manually cleaning tooth surfaces is disclosed. The disposable tooth cleaning article extends in a longitudinal direction and a transverse direction, and has a finger faced surface and an outer surface. The disposable tooth cleaning article comprises a single sheet. The outer surface is provided with a diamond dust polishing agent for home use and professional use in the care of natural tooth enamel and dental veneers comprised of a quantity of diamond dust coated with a lubricant in conjunction with a paste for carrying the lubricant coated diamond dust, or other semi-precious, non-toxic abrasive dust, said diamond dust being of a size of approximately 500 nanometers or less to a size of approximately 5 nanometers. The size of the dust of both the diamond and the semi-precious stone may vary, depending on the degree of abrasiveness and the lubricant employed. The diamond dust (and semi-precious dust) polishing agent permits the user to maintain the polish and luster of the natural tooth enamel and veneer at home without adversely abrading or damaging the surface thereof.

Priority: US20070003552P Applic. Date: 2007-11-16

Inventor: HERMAN MICHAEL [US]

Title: Tongue scraper

Applicant/Assignee:

Application No.: 11/985954   Filing Date: 19/Nov/2007

Abstract:

The present invention is a tongue cleaning device that reduces or eliminates the gag reflex during use comprising, a body having a first end and a second end. The first end forming an elongated handle having a contour for ease of handling and use and a gripping means. The second end forming a head having two or more elongated apertures forming at least two parallel ridges perpendicular to the handle. The head being flat and narrow in width and the body being narrow in thickness thereby eliminating or reducing the gag reflex during use.

Priority:

Inventor: PANTANGCO III IRINEO MARVIN [US]

Title: LAMP HOLDER

Applicant/Assignee: BJB GMBH & CO. KG

Application No.: 12/191806   Filing Date: 14/Aug/2008

Abstract:

A bipin fluorescent-lamp holder has a housing formed with an outwardly open housing mouth and a rotor rotatable in the housing adjacent the mouth about an axis and having a diametrally throughgoing rotor slot. The rotor is rotatable between an installation position with the rotor slot aligned with the slot and an angularly offset contact position with the slot not aligned with the mouth. The rotor and housing are so dimensioned as to receive the pins extending parallel to the axis and to move the pins in a circular orbit centered on the axis on rotation of the rotor in the housing, and contacts in the housing diametrally flanking the axis each having a main part lying outside the orbit and a contact part engageable into the orbit. The contacts pins are aligned with the slot and project into ends of the slot and into engagement with the pins only in the contact position of the rotor.

Priority: DE200710054930 Applic. Date: 2007-11-17; DE200710051431 Applic. Date: 2007-10-25

Inventor: VOGT KARL-WILHELM [DE]; GRESCHNER HARTMUT [DE]; NASSE MARKUS [DE]

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 12/157150   Filing Date: 06/Jun/2008

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2007-656921 Applic. Date: 2007-01-22; US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]

Title: PAR-2 AGONIST

Applicant/Assignee: KOWA CO., LTD

Application No.: 11/722952   Filing Date: 27/Dec/2005

Abstract:

Disclosed is a compound represented by the following general formula (1): Ar-CO-AA1-AA2-AA3-AA4-NH-X-NR1R2 (1) (wherein Ar represents an optionally substituted phenyl group or an aromatic heterocyclic group

AA1 represents a hydrophobic amino acid

AA2 represents an unsubstituted amino acid containing 2 or more carbon atoms

AA3 represents an unsubstituted amino acid containing 2 or more carbon atoms

AA4 represents a hydrophobic amino acid

X represents a divalent saturated aliphatic hydrocarbon group having 2-6 carbon atoms

and R1 and R2 may be the same or different and independently represent a saturated or unsubstituted aliphatic hydrocarbon group having 1-8 carbon atoms, or alternatively R1 and R2 may form a ring together with an adjacent nitrogen atom), a salt thereof, or a solvate of them. Also disclosed is a pharmaceutical composition for prevention/treatment of diseases associated with PAR-2 which is composed of the compound represented by the above general formula (1), a salt thereof or a solvate of them and a pharmaceutically acceptable carrier.

Priority: US20040639403P Applic. Date: 2004-12-28; WO2005JP23852 Applic. Date: 2005-12-27

Inventor: ISHIWATA HIROYUKI [JP]; KABEYA MOTOTSUGU [JP]; KANKE TORU [JP]

Title: Transcription factor modulating compounds and methods of use thereof

Applicant/Assignee: PARATEK PHARMACEUTICALS, INC

Application No.: 12/069723   Filing Date: 12/Feb/2008

Abstract:

Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.

Priority: US2003-700661 Applic. Date: 2003-11-03; US2002-139591 Applic. Date: 2002-08-14; US20020423319P Applic. Date: 2002-11-01; US20020425916P Applic. Date: 2002-11-13; US20010288660P Applic. Date: 2001-05-04

Inventor: LEVY STUART B [US]; ALEKSHUN MICHAEL N [US]; PODLOGAR BRENT L [US]; OHEMENG KWASI [GH]; VERMA ATUL K [US]; WARCHOL TADEUSZ [US]; BHATIA BEENA [US]; BOWSER TODD [US]; GRIER MARK [US]

Title: HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS

Applicant/Assignee:

Application No.: 12/269108   Filing Date: 12/Nov/2008

Abstract:

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20070987485P Applic. Date: 2007-11-13; US20080088141P Applic. Date: 2008-08-12

Inventor: STAMOS DEAN [US]; MARTINBOROUGH ESTHER [US]; ZIMMERMANN NICOLE [US]; NEUBERT TIMOTHY [US]; NUMA MEHDI MICHEL DJAMEL [US]; WHITNEY TARA [US]; KAWATKAR AARTI SAMEER [US]

Title: POLYFUNCTIONAL COMPOUNDS AND USES AS IMPLANT MATERIALS

Applicant/Assignee:

Application No.: 12/280929   Filing Date: 27/Feb/2007

Abstract:

The synthesis and characterization of polymer core initiators are described herein. Polymer core initiators are used to prepare the polyfunctional prepolymers described herein, which may be optionally tethered. The polyfunctional prepolymers described herein are used to prepare cements, optionally with added co-monomers, for repairing and restoring tissues.

Priority: US20060777827P Applic. Date: 2006-03-01; WO2007US62882 Applic. Date: 2007-02-27

Inventor: XIE DONG [US]

Title: 3D dental shade matching and apparatus

Applicant/Assignee: IOS TECHNOLOGIES, INC

Application No.: 11/986642   Filing Date: 26/Nov/2007

Abstract:

Systems and methods are disclosed to fabricate a restorative prosthesis. The system includes a scanner to intra orally capture color and translucency information along with a three dimensional (3D) shape of the dentition being reconstructed. The system also includes a computer aided design (CAD) module to receive the color and translucency information and the 3D shape to render a color accurate representation of the prosthesis for review, wherein the color, translucency and surface information is combined in a single digital prescription which is electronically transferred to a laboratory or CAD/CAM system for fabrication. The system provides the capability for 3D shape, color and translucency characteristics of the final prosthesis to be measured and quantitatively compared to the prescribed requirements.

Priority:

Inventor: DURBIN DUANE MILFORD [US]; DURBIN DENNIS ARTHUR [US]; DYMEK MARTY J [US]; WARDEN LAURENCE [US]

Title: Oral Stannous Compositions

Applicant/Assignee:

Application No.: 12/266937   Filing Date: 07/Nov/2008

Abstract:

The present invention relates to an aqueous oral composition comprising: a) from 0.2% to 3% divalent metal ions comprising: i. from 0.1% to 1.5% of zinc ions

ii. from 0.1% to 2% of tin (II) ions

and b) a source of fluoride ions

c) a silica dental abrasive

d) one or more chelants having a MW of less than 1000 and capable of forming water-soluble complexes with the zinc ions, wherein the chelants comprise less than 0.2% linear polyphosphates having a chain length of four or more

e) an orally acceptable carrier comprising at least 20% total water

wherein the pH of the composition is from 5 to 6.5, the molar ratio of the chelants to the divalent metal ions is at least 0.70:1 and at least 80% by weight of the total zinc ions are solubilised within the composition. The composition of the invention has been found to give improved antimicrobial activity from the zinc/stannous combination without significant taste, staining or stability problems, compared to compositions having lower levels of chelants.

Priority: EP20070120425 Applic. Date: 2007-11-09

Inventor: STRAND ROSS [GB]; PRENDERGAST MAURICE JOSEPH [GB]; WANG XIAOLI [CN]

Title: Biomarkers for human papilloma virus-associated cancer

Applicant/Assignee:

Application No.: 12/220465   Filing Date: 24/Jul/2008

Abstract:

Cervical cancer cells and HPV+ head and neck cancer cells express three testis-specific genes not normally expressed in somatic cells: testicular cell adhesion molecule 1 (TCAM1), synaptonemal complex protein 2 (SYCP2) and stromal antigen 3 (STAG3). Among the three markers, TCAM1 and SYCP2 are early detection markers. Various methods for identifying a human or non-human animal as a candidate for further examination for cervical cancer, preneoplastic lesion for cervical cancer, head and neck cancer, or preneoplastic lesion for head and neck cancer are disclosed. Methods of detecting said cancers and preneoplastic lesions, methods of screening for drugs for treating said cancers and preneoplastic lesions, methods for monitoring the effectiveness of a treatment for said cancers, and methods of treating said cancers are also disclosed. Further disclosed are kits that can be used to practice the above methods.

Priority: US20070961774P Applic. Date: 2007-07-24

Inventor: PYEON DOHUN [US]; LAMBERT PAUL F [US]; NEWTON MICHAEL A [US]; AHLQUIST PAUL G [US]

Title: TOOTHPASTE

Applicant/Assignee: KAO CORPORATION

Application No.: 12/359385   Filing Date: 26/Jan/2009

Abstract:

A toothpaste filled in a container which has two chambers and is capable of simultaneously discharging two different compositions filled respectively in the two chambers when the main body of the container is pressed, wherein a ratio of a storage modulus GA' of Composition (A) filled in one chamber to a storage modulus GB' of Composition (B) filled in the other chamber falls within a range of from 0.6 to 1.4. By controlling the ratio, it is possible to stably discharge from the container storing these two compositions separately predetermined amounts of these two compositions which will otherwise cause a time-dependent change if they are pre-mixed thereby failing to attain the purpose of their addition.

Priority: JP20010327367 Applic. Date: 2001-10-25; JP20020065550 Applic. Date: 2002-03-11; US2004-492199 Applic. Date: 2004-04-21; WO2002JP11099 Applic. Date: 2002-10-25

Inventor: HOSOYA MANABU [JP]; OSHINO KAZUSHI [JP]; MATSUMOTO HIROMASA [JP]; KITSUNAI YOSHITAKA [JP]

Title: Oral appliance for delivering a medicament

Applicant/Assignee:

Application No.: 11/986727   Filing Date: 26/Nov/2007

Abstract:

An oral appliance is provided for delivering a medicament to at least a portion of teeth and/or soft tissue areas inside a mouth, the oral appliance comprising an interior surface having a porous material disposed on at least a portion of the interior surface of the oral appliance, the porous material containing a medicament and the interior surface being formed to fit contours of at least the portion of the teeth and/or soft tissue areas inside the mouth and being capable of supporting and holding the porous material in contact with at least the portion of the teeth and/or soft tissue areas inside the mouth to deliver the medicament.

Priority:

Inventor: ZEGARELLI PETER JOHN [US]

Title: DENTAL APPARATUS FOR SHAPING AND CLEANING A ROOT CANAL

Applicant/Assignee: MICRO MEGA INTERNATIONAL MANUFACTURES (SOCIETE ANONYME)

Application No.: 12/160274   Filing Date: 10/Jan/2007

Abstract:

Apparatus is disclosed for use in cleaning dental root canals using an endodontic file. The file is mounted in a drill head driven by an electric motor. The motor is normally driven in one, forward direction, but periodically, the motor rotation is reversed for a very short time. The duration of the motor reversal is so short that although the motor rotates in the reverse direction, the inertia and backlash in the transmission between the motor output shaft and the drill head is such that the direction of rotation of the file in the root canal is not changed.

Priority: GB20060001361 Applic. Date: 2006-01-24; WO2007IB00546 Applic. Date: 2007-01-10

Inventor: MEYER SHUSTER DAVID [GB]

Title: METHOD AND DEVICE TO FRACTIONATE STEM CELLS

Applicant/Assignee:

Application No.: 12/299350   Filing Date: 30/Apr/2007

Abstract:

A method and the relevant instrumentation to fractionate living, adherent stem cells, particularly of human origin, from different sources is disclosed, said method is based on the non-equilibrium, dynamic fractionation of cells assisted by the Earth gravity field.

Priority: IT2006RM00240 Applic. Date: 2006-05-04; IT2006RM00572 Applic. Date: 2006-10-24; WO2007EP54226 Applic. Date: 2007-04-30

Inventor: RESCHIGLIAN PIERLUIGI [IT]; RODA BARBARA [IT]; BAGNARA GIAN PAOLO [IT]; ZATTONI ANDREA [IT]

Title: TRANSDERMAL DELIVERY SYSTEM FOR DRIED PARTICULATE OR LYOPHILIZED MEDICATIONS

Applicant/Assignee:

Application No.: 12/357283   Filing Date: 21/Jan/2009

Abstract:

The present invention provides a system for transdermal delivery of dried or lyophilized pharmaceutical compositions and methods using thereof. The system comprises an apparatus for facilitating transdermal delivery of an agent that generates hydrophilic micro-channels, and a patch comprising a therapeutically active agent. The present invention is useful for transdermal delivery of hydrophilic agents, particularly of high molecular weight proteins.

Priority: IL20020152574 Applic. Date: 2002-10-31; US2006-582920 Applic. Date: 2006-10-17; US2003-699582 Applic. Date: 2003-10-31

Inventor: STERN MEIR [IL]; LEVIN GALIT [IL]

Title: SULFONYL BENZIMIDAZOLE DERIVATIVES

Applicant/Assignee: PFIZER INC

Application No.: 12/280586   Filing Date: 23/Feb/2007

Abstract:

This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein A, R1, R2, R3, R4, R5, m and n are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity such as, but not limited to, inflammatory pain, nociceptive pain, neuropathic pain, fibromyalgia, chronic low back pain, visceral pain, acute cerebral ischemia, pain, chronic pain, acute pain, post herpetic neuralgia, neuropathies, neuralgia, diabetic neuropathy, HIV-related neuropathy, nerve injury, rheumatoid arthritic pain, osteoarthritic pain, back pain, cancer pain, dental pain, fibromyalgia, neuritis, sciatica, inflammation, neurodegenerative disease, cough, broncho constriction, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), colitis,

cerebrovascular ischemia, emesis such as cancer chemotherapy-induced emesis, rheumatoid arthritis, asthma, Crohn's disease, ulcerative colitis, asthma, dermatitis, seasonal allergic rhinitis, GERD, constipation, diarrhea, functional gastrointestinal disorders, irritable bowel syndrome, cutaneous T cell lymphoma, multiple sclerosis, osteoarthritis, psoriasis, systemic lupus erythematosus, diabetes, glaucoma, osteoporosis, glomerulonephritis, renal ischemia, nephritis, hepatitis, cerebral stroke, vasculitis, myocardial infarction, cerebral ischemia, reversible airway obstruction, adult respiratory disease syndrome, COPD, cryptogenic fibrosing alveolitis and bronchitis.

Priority: US20060779776P Applic. Date: 2006-03-06; US20060795354P Applic. Date: 2006-04-26; WO2007IB00474 Applic. Date: 2007-02-23

Inventor: KATO TOMOKI [JP]; KON-I KANA [JP]; YUKI YOHEI [JP]; ANDO KAZUO [JP]

Title: USE OF HAPTOGLOBIN GENOTYPING IN DIAGNOSIS AND TREATMENT OF CARDIOVASCULAR DISEASE

Applicant/Assignee:

Application No.: 12/276963   Filing Date: 24/Nov/2008

Abstract:

This invention is directed to methods and compositions for the treatment of cardiovascular disorders. Specifically, the invention is directed to compositions comprising vitamin E, statins and/or glutathione peroxidase mimetics

methods of treating diabetic patients expressing the Hp-2-2 haptoglobin genotype

a method of inhibiting or suppressing a cardiovascular disorder in a diabetic subject, treating cardiovascular disease in subjects exhibiting the Haptoglobin Hp-2-2 genotype

and methods of treating cardiovascular disease in subjects exhibiting the Haptoglobin Hp-2-2 genotype.

Priority: US20070996552P Applic. Date: 2007-11-23

Inventor: LEVY ANDREW [IL]

Title: Novel Enantiomers and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/887246   Filing Date: 06/Apr/2006

Abstract:

This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000505 Applic. Date: 2005-04-08; DK20050001572 Applic. Date: 2005-11-11; US20050669918P Applic. Date: 2005-04-11; US20050736331P Applic. Date: 2005-11-15; WO2006EP61363 Applic. Date: 2006-04-06

Inventor: PETERS DAN [SE]; DAHL BJARNE H [DK]; OLESEN DORTHE FILTENBORG [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; OLSEN GUNNAR M [DK]; REDROBE JOHN PAUL [DK]

Title: Dental Curable Composition and Kit for Such Dental Curable Composition

Applicant/Assignee: SUN MEDICAL CO., LTD

Application No.: 12/063200   Filing Date: 08/Aug/2006

Abstract:

A dental curable composition has a curing time of 30 seconds to 120 minutes and includes a compound having an acidic group in the molecule (A), a polymerizable monomer (B), an organic amine compound (C) and a sulfur-containing reducing compound (D). In the dental curable composition, the content of the component (A) is 0.01 to 80 parts by weight, the content of the component (B) is 21 to 99.8 parts by weight, the content of the component (C) is 0.01 to 30 parts by weight and the content of the component (D) is 0 to 30 parts by weight. The composition may be cured at a relatively low temperature close to the body temperature without using a peroxide-based polymerization initiator, and has good sealing properties and adhesion.

Priority: JP20050229625 Applic. Date: 2005-08-08; WO2006JP315685 Applic. Date: 2006-08-08

Inventor: ORI TATSUYA [JP]; NISHITANI HARUKA [JP]; YAMAMOTO YUYA [JP]; YAMAMOTO TAKASHI [JP]

Title: Process for preparing low-viscosity allophanates containing actinically curable groups

Applicant/Assignee:

Application No.: 12/229185   Filing Date: 20/Aug/2008

Abstract:

The present invention relates to a process for preparing low-viscosity reaction products of polyisocyanates containing activated groups which react, with polymerization, with ethylenically unsaturated compounds on exposure to actinic radiation.

Priority: DE200710040240 Applic. Date: 2007-08-25

Inventor: LUDEWIG MICHAEL [DE]; FISCHER WOLFGANG [DE]; KUCZEWSKI HELMUT [DE]

Title: DENTAL MATERIALS BASED ON ALKYLENEDIAMINE-N,N,N',N'- TETRAACETIC ACID- (METH)ACRYLAMIDES

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 12/207622   Filing Date: 10/Sep/2008

Abstract:

The present invention relates to an alkylenediamine-N,N,N',N'-tetraacetic acid-(meth)acrylamide of formula (I) The invention also relates to a polymerizable composition which is characterized in that it comprises at least one alkylenediamine-N,N,N',N'-tetraacetic acid-(meth)acrylamide of formula (I), and its use in particular as dental material.

Priority: EP20070023228 Applic. Date: 2007-11-30

Inventor: MOSZNER NORBERT [LI]; ANGERMANN JORG [CH]; FISCHER URS KARL [CH]; RHEINBERGER VOLKER M [LI]

Title: NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS

Applicant/Assignee:

Application No.: 11/719335   Filing Date: 15/Nov/2005

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20040627822P Applic. Date: 2004-11-15; WO2005US41230 Applic. Date: 2005-11-15

Inventor: BUDZIK BRIAN W [US]