Title: Method and preparation for binding aldehydes in saliva

Applicant/Assignee: BIOHIT OYJ

Application No.: 11/783333   Filing Date: 09/Apr/2007

Abstract:

The object of the invention is the use of compounds comprising one or more free sulphlydryl or amino groups for preparing a pharmaceutical composition for locally binding acetaldehyde in saliva, the stomach or the large intestine, and pharmaceutical compositions comprising the said compounds.

Priority: FI20000002392 Applic. Date: 2000-10-30; WO2005FI00429 Applic. Date: 2005-10-10; US2003-415422 Applic. Date: 2003-11-21; WO2001FI00948 Applic. Date: 2001-10-30; US20040617299P Applic. Date: 2004-10-08; US20050660723P Applic. Date: 2005-03-11

Inventor: SUOVANIEMI OSMO [FI]; SALASPURO MIKKO [FI]; SALASPURO VILLE [FI]; MARVOLA MARTTI [FI]

Title: HOT FLAVOR AND SKIN SENSATION COMPOSITION

Applicant/Assignee:

Application No.: 11/853656   Filing Date: 11/Sep/2007

Abstract:

The present invention relates to a flavor and skin sensation composition providing a hot or warming sensation upon consumption or application, respectively. The composition comprises a hot, warming component, a cooling component and a bitter component. In an embodiment, the composition further comprises an acid component. The composition provides a clean hot taste free of oily or earthy off-notes. Consumers prefer the composition over hot, warming compositions comprising essentially natural extracts.

Priority: EP20050102993 Applic. Date: 2005-04-15; WO2006IB51102 Applic. Date: 2006-04-11

Inventor: MAUREL CATHERINE D [CH]; LE ANH [US]; BARRA JEROME [FR]; STARKENMANN CHRISTIAN [CH]

Title: Device and method for forming water vapor

Applicant/Assignee:

Application No.: 11/707790   Filing Date: 15/Feb/2007

Abstract:

A device and method are provided for forming vapor mainly utilizing the atomization device to form low temperature water vapor, and then using an adjustable heating unit to warm the low temperature water vapor, or mixing some high temperature steam to get needed temperature water vapor. The invention uses the atomization device which mainly was used to humidify the air to form the needed water vapor in beauty, hairdressing, or health care so as to adjust the temperature of water vapor to solve the problems which are existing in the fields of beauty, hairdressing, health care, where the high temperature steam scalds a person more easily, and the temperature is difficult to control. The present invention makes the application of the steam in these fields more free, common and popular.

Priority: CN20061045326 Applic. Date: 2006-06-30

Inventor: YOU TUMING [CN]

Title: Brand protection and product autentication using portable devices

Applicant/Assignee:

Application No.: 11/477486   Filing Date: 30/Jun/2006

Abstract:

The present invention is a method and apparatus for protection of products and packaging against counterfeiting using dedicated authentication protocol coupled with portable devices. It is based on the product identification information, i.e., PIN, generated by the product manufacturer, stored in the product database and added to product or packaging in an open and/or a hidden form. The open part is directly available to the consumer before buying, opening or consuming the product or package or damaging its integrity while the hidden part is only revealed after these operations. The hidden information can also be disappearing after a predefined interval of time or number of trials or usages. Both parts are communicated to the authentication server in a predefined order to verify the product or package authenticity. The presence, absence, or multiple requests for the same product PIN, confirm or reject product authenticity or detect attempt at attacking the system or at using counterfeited products.

Priority:

Inventor: VOLOSHYNOVSKYY SVYATOSLAV [CH]; KOVAL OLEKSIY [CH]; PUN THIERRY [CH]

Title: High fluoride ion oral care composition and method for maintaining anticaries activity

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 11/479678   Filing Date: 30/Jun/2006

Abstract:

An oral care composition and method of maintaining anticaries activity of fluoride ion in an oral care composition are described. An oral care composition comprises a fluoride ion source sufficient to maintain a high fluoride content in the composition, an effective amount of a desensitizing agent and water. A method of maintaining anticaries activity of fluoride ion in an oral care composition comprises providing an oral care composition comprising fluoride ions, an effective amount of a desensitizing agent and water.

Priority:

Inventor: JOZIAK MARILOU T [US]; FISHER STEVEN W [US]

Title: Modified interferon-beta (IFN-beta) polypeptides

Applicant/Assignee:

Application No.: 11/729266   Filing Date: 27/Mar/2007

Abstract:

Provided are modified interferon-beta polypeptides and nucleic acid molecules encoding modified interferon-beta polypeptides and formulations containing the polypeptides and/or nucleic acid molecules. The modified polypeptides exhibit increased protein stability, including increased resistance to proteases. Also provided are methods of treatment by administering modified interferon-beta polypeptides.

Priority: US20060787208P Applic. Date: 2006-03-28

Inventor: GUYON THIERRY [FR]; BORRELLY GILLES [FR]; DRITTANTI LILA [FR]; VEGA MANUEL [FR]

Title: Products made with yellow mustard gum

Applicant/Assignee:

Application No.: 11/475952   Filing Date: 28/Jun/2006

Abstract:

Yellow mustard gum was used to produce varieties of new foods, cosmetics, paints, and industrial products including but not limited to the following products: nutraceutical beverages, nutraceutical sauces, nutraceutical salad dressings, nutraceutical confectionary products, cosmetics products, pharmaceutical products, paints products and chemical products and were claimed accordingly.

Priority:

Inventor: SHARAFABADI SOHEIL K [CA]

Title: Pharmaceutical Composition

Applicant/Assignee:

Application No.: 11/666086   Filing Date: 20/Oct/2005

Abstract:

The invention relates to pharmaceutical compositions suitable for oral administration in the form of edible films comprising diclofenac.

Priority: US20040620706P Applic. Date: 2004-10-21; WO2005US38090 Applic. Date: 2005-10-20

Inventor: SPENCER GAVIN M [FR]; SCHOBEL ALEXANDER M [US]; SLOMINSKI GREG [US]; MEYER STEPHAN [CH]; RAULT ISABELLE [FR]

Title: Electrochemically treating teeth

Applicant/Assignee: FLUORINEX ACTIVE LTD

Application No.: 11/476787   Filing Date: 29/Jun/2006

Abstract:

Electrochemical method for treating teeth: applying metal salt solution to teeth, applying ionizable substance to the teeth, and applying current flow to the teeth so as to ionize the ionizable substance. Electrochemical device for dental treatment: applicator for applying a substance to teeth, having a first end and a second end, a first electrode attached to first end of applicator, second electrode attached to second end of applicator, wherein first electrode and second electrode are configured for current flow through applicator, and an ionizable substance for placement within applicator, wherein ionizable substance is configured for ionization upon application of current flow through the substance.

Electrochemical teeth whitening method: applying metal salt solution to teeth, applying an oxidizing agent to teeth exposed to metal salt solution, and applying current flow to the teeth so as to activate and reduce the oxidizing agent for effecting whitening of the teeth.

Priority: WO2004IL01174 Applic. Date: 2004-12-29; US20030532570P Applic. Date: 2003-12-29

Inventor: KHAWALED KAMAL [IL]; JUBEH MAHER [IL]

Title: 3,8-Substituted 8-Aza-Bicyclo[3.2.1]Octane Derivatives and Their Use as Monomine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 11/794365   Filing Date: 11/Jan/2006

Abstract:

This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000068 Applic. Date: 2005-01-13; US20050643590P Applic. Date: 2005-01-14; WO2006EP50143 Applic. Date: 2006-01-11

Inventor: PETERS DAN [DK]; DAHL BJARNE H [DK]; OLSEN GUNNAR M [DK]; NIELSEN ELSEBET O [DK]; SCHEEL-KRUGER JORGEN [DK]; REDROBE JOHN P [DK]

Title: Inhibitors of TNFalpha, PDE4 and B-RAF, compositions thereof and methods of use therewith

Applicant/Assignee:

Application No.: 11/654344   Filing Date: 16/Jan/2007

Abstract:

Provided herein are compounds having TNFalpha and/or PDE4 and/or B-RAF inhibitory activity, and compositions thereof. In particular, provided herein are compounds of the formula I: and pharmaceutically acceptable salts, solvates, hydrates, clathrates, stereoisomers, polymorphs and prodrugs thereof, wherein Ar, R<1>, R<2>, R<3>, R<4>, n and Z are as described herein. Further provided herein are methods for treating or preventing various diseases and disorders by administering to a patient one or more TNFalpha and/or PDE4 and/or B-RAF inhibitors. In particular, provided herein are methods for preventing or treating cancer, inflammatory disorders, cognition and memory disorders and autoimmune disorders, or one or more symptoms thereof by administering to a patient one or more TNFalpha and/or PDE4 and/or B-RAF inhibitors.

Priority: US20060759819P Applic. Date: 2006-01-17; US20060814862P Applic. Date: 2006-06-19; US20060818246P Applic. Date: 2006-06-30; US20060854637P Applic. Date: 2006-10-25

Inventor: MCKENNA JEFFREY M [GB]; PAPA PATRICK W [US]; SAKATA STEVEN T [US]; ERDMAN PAUL E [US]; PACKARD GARRICK K [US]

Title: New Anticonvulsant Compounds

Applicant/Assignee: HEJ RESEARCH INSTITUTE OF CHEMISTRY HEJ RESEARCH INSTITUTE KARACHI UNIVERSITY

Application No.: 11/307251   Filing Date: 01/Jul/2006

Abstract:

The invention relates to novel isoxylitones and their use as anticonvulsant and in the treatment of a variety of disorders

Priority:

Inventor: RAHMAN ATTAUR [PK]; CHOUDHARY MOHAMMAD IQBAL [PK]; SHAHEEN FARZANA [PK]; GANESAN A [GB]; SIMJEE SHABANA USMAN [PK]; RAZA A MOHSIN [PK]

Title: Dental Adhesive Composition

Applicant/Assignee: DENTSPLY DETREY GMBH

Application No.: 11/572613   Filing Date: 13/May/2005

Abstract:

One component dental adhesive composition having a pH of at most 3, comprising (a) a polymerisable acrylate monomer or prepolymer, (b) a photoinitiator, and (c) a solvent comprising t-butanol.

Priority: EP20040017749 Applic. Date: 2004-07-27; WO2005EP05263 Applic. Date: 2005-05-13

Inventor: BLACKWELL GORDON B [DE]

Title: Crosslinkable Biopolymer

Applicant/Assignee:

Application No.: 11/667929   Filing Date: 03/Nov/2005

Abstract:

The invention discloses composition, prepolymer and method to produce a polymer based on biodegradabler or essentially renewable crude materials, which can be crosslinked by free radicals. Composition is based on polyesters that are functionalised with unsaturated monomer units, in a way that unsaturated groups can be located along the polymer main chain as well as at the ends of the prepolymer. In connection to the product production, the prepolymer shall be exposed to free radicals that leads to network formation. The composition of the crosslinked biopolymer can be adjusted from a stiff engineering material to an elastic rubbery material. The new biopolymer can be used in composite materials, dispersions, barrier materials, rubbery materials, and in biomedical applications to mention a few possible application areas.

Priority: FI20040001476 Applic. Date: 2004-11-17; WO2005FI00471 Applic. Date: 2005-11-03

Inventor: SEPPALA JUKKA [FI]

Title: ORAL CARE IMPLEMENT

Applicant/Assignee:

Application No.: 11/852621   Filing Date: 10/Sep/2007

Abstract:

An oral care implement with a handle includes a head with a releasable material (e.g., an oral medicament) and a tissue cleanser for cleaning the soft tissues and removing odor-causing bacteria from the mouth. In one arrangement, the releasable material is disposed on the surface of the tissue cleanser. In one arrangement, the releasable material is disposed behind the tissue cleanser. In one arrangement, the releasable material is incorporated in the composition of the tissue cleanser.

Priority: US2004-986809 Applic. Date: 2004-11-15; US2004-869922 Applic. Date: 2004-06-18; US2003-601106 Applic. Date: 2003-06-20; US20040600701P Applic. Date: 2004-08-11

Inventor: HOHLBEIN DOUGLAS J [US]; WONG CHI SHING [US]

Title: Flossing Device With Internal Floss Feed

Applicant/Assignee:

Application No.: 11/858232   Filing Date: 20/Sep/2007

Abstract:

A flossing device having internal floss feed in which floss is advanced from a storage chamber inside the handle of the device, through feed gears, to a pair of spaced apart tines. Spent floss is returned through the return gears, the return drive gear having a greater diameter than the feed drive gear, thus ensuring the floss remains taut between the tines. An integral cutter allows the spent floss to be cut off and discarded. The cover over one or both sets of gears may be open at the top and bottom to allow cleaning of the gears. A flexible tile may be included over the aperture through which the floss exits the storage chamber to prevent water incursion therein. A floss advance lever advances the floss by a single action when pressed forward, which creates and maintains sufficient tensions on the floss resulting in taut and snug floss between the tines.

Optionally, the flossing head has a vibratory device to aid in the flossing action.

Priority: US2004-846575 Applic. Date: 2004-05-17

Inventor: FILSOUF EHSAN [US]

Title: Automatic swing-away knife sheath retaining strap

Applicant/Assignee: HEDGEHOG LEATHERWORKS LLC

Application No.: 11/481715   Filing Date: 06/Jul/2006

Abstract:

A knife sheath is provided. In various embodiments, the knife sheath includes an automatic swing-away retention strap that includes at least one biasing device. The biasing device is adapted to automatically pivot a detachable distal end of the retention strap about a fixed proximal end of the retention strap to swing the retention strap from a fastened position to an open position.

Priority:

Inventor: SCHEITER PAUL ALAN [US]

Title: Antimicrobially active compounds for treating bad breath

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 11/812085   Filing Date: 14/Jun/2007

Abstract:

The invention relates primarily to specific uses of a compound of the Formula 1 or of mixtures of two or more different compounds of the Formula 1, in particular for producing an antimicrobially acting agent and agent against bad breath, as well as the corresponding production methods. In addition the invention relates to specific products, in particular oral hygiene products, comprising or consisting of a compound of the Formula 1 or of a mixture of two or more different compounds of the Formula 1 wherein the radicals of the compound of the Formula 1 or of each compound of the Formula 1 in the mixture are as defined in the preceding description.

Priority: WO2006EP63175 Applic. Date: 2006-06-14; US20060842999P Applic. Date: 2006-09-08

Inventor: RABENHORST JURGEN [DE]; MACHINEK ARNOLD [DE]; SCHMAUS GERHARD [DE]; HERRMANN MARTINA [DE]; VIELHABER GABRIELE [DE]; PILLAI RAVIKUMAR [US]

Title: Breath Test for Oral Malodor

Applicant/Assignee:

Application No.: 10/592552   Filing Date: 14/Mar/2005

Abstract:

Measured of airway in samples a mammal, such as a human being, having oral malodor are analyzed for the presence of markers for the oral malodor. The mammal may subsequently be treated for this condition, and measured samples of airway breath again taken to determine the effectiveness of the treatment.

Priority: US20040552566P Applic. Date: 2004-03-12; US20040562742P Applic. Date: 2004-04-16; WO2005US08553 Applic. Date: 2005-03-14

Inventor: PHILLIPS MICHAEL [US]

Title: PERSONAL CARE COMPOSITIONS WITH GLYCERIN AND HYDROXYPROPYL QUATERNARY AMMONIUM SALTS

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 11/851405   Filing Date: 07/Sep/2007

Abstract:

A personal care composition is provided formulated with glycerin and a moisturization enhancing agent which is a salt of structure AB, wherein A is a cationic charged component, B is an anionic charged component, and A has at least one quaternized nitrogen atom and at least two hydroxyl groups and a molecular weight no higher than about 400.

Priority: US2005-222104 Applic. Date: 2005-09-08; US2004-972483 Applic. Date: 2004-10-25

Inventor: HARICHIAN BIJAN [US]; MCMANUS RICHARD L [US]; HURLEY MEGAN K [US]; MINER PHILIP E [US]; CHANDAR PREM [US]; BARROW STEPHEN R [US]

Title: Odor eliminating items and methods of use for hunting

Applicant/Assignee: JOHNSON LABORATORIES, INC

Application No.: 11/898873   Filing Date: 17/Sep/2007

Abstract:

A regimen for hunting includes using a number of zeolite-containing personal items in connection with a hunter's apparel and body to reduce the hunter's scent for improved hunting. The personal items include mouthwash, deodorant/anti-perspirant, body and boot powder, bar and liquid soap for cleansing the body and hair, laundry detergent and dryer sheets. Each of the personal items includes an effective amount of zeolite, so that use of the personal items reduces the available scent to be detected by animals in the wild. The regimen can also include the use of a seat cushion that is covered with an activated carbon-containing fabric for odor control and/or elimination.

Priority: US2005-082777 Applic. Date: 2005-03-18; US2002-141075 Applic. Date: 2002-05-09; US2000-574208 Applic. Date: 2000-05-19; US19990136760P Applic. Date: 1999-05-28

Inventor: JOHNSON LOUIS B [US]

Title: Dehydrated dentifrice and toothbrush

Applicant/Assignee:

Application No.: 11/818316   Filing Date: 14/Jun/2007

Abstract:

A toothbrush has one or two part-spherical pockets formed in the brush surface. Balls or pellets of matching shape of dehydrated toothpaste are placed in the depressions, the brush is wetted and the pellets turn to a gel, ready for brushing. The pellets may be of various colors and flavors to entice children to brush their teeth and may be dispensed from a storage chamber carried in the tooth brush handle.

Priority: US20060813383P Applic. Date: 2006-06-14

Inventor: ATKIN JOSHUA D [US]

Title: Treatment of urinary tract infections

Applicant/Assignee:

Application No.: 11/481210   Filing Date: 05/Jul/2006

Abstract:

The invention provides a method for treating urinary tract infections in a patient by providing a mouth rinsing composition which releases free molecular iodine into the mucous membranes which enters into the urinary tract.

Priority:

Inventor: SIEGEL GREGG [US]; SIEGEL PHYLLIS [US]

Title: Laser augmented periodontal scaling instruments

Applicant/Assignee: NOMIR MEDICAL TECHNOLOGIES, INC

Application No.: 11/825550   Filing Date: 06/Jul/2007

Abstract:

An instrument is provided to enables a dental professional to subject a surgical site simultaneously to (1) mechanical cutting, scraping and grinding, and (2) laser trimming and cauterization. As a result, simultaneous removal of diseased tissue and destruction of residual bacteria is enabled. The instrument comprises a hollow shank having, a rearward fitting, and a forward contact head. Within shank extends a fiber optic bundle. As shown, laser energy is delivered from a laser through the fitting and the laser bundle to the contact head. In the contact head are a surgical blade and an exit window for the laser energy.

Priority: US2003-723031 Applic. Date: 2003-11-26; US20020430294P Applic. Date: 2002-12-02

Inventor: BORNSTEIN ERIC [US]

Title: Game caller

Applicant/Assignee:

Application No.: 11/820778   Filing Date: 20/Jun/2007

Abstract:

A game caller wherein a reed assembly thereof may be replaced or interchanged and marketed in customized kits provided with elements for repairing or customizing the game caller, and a horn piece thereof is comprised of a pliable material that is pinched, or squeezed, or manipulated, or otherwise deformed by the hunter into a closed relation, at least in part, to change the volume of air through the horn piece and sound pipe whereby to imitate distress sounds during a hunting situation wherein game is coaxed and/or attracted.

Priority: US20060815002P Applic. Date: 2006-06-20

Inventor: LOMBARDI JAMES S [US]

Title: Light emitting diode curable acrylates with reduced yellowing

Applicant/Assignee: BISCO, INC

Application No.: 11/481544   Filing Date: 06/Jul/2006

Abstract:

Dental compositions and methods of curing the composition utilizing a light emitting diode (LED) curing unit. According to one aspect, a composition comprising a multiacrylate compound, an initiator including camphorquinone and at least one amine, and a colorless anti-yellowing agent produces a scratch free surface having no oxygen inhibited layer when cured with the LED curing unit.

Priority:

Inventor: FENG LI [US]; SUH BYOUNG I [US]

Title: METHOD AND DEVICE FOR CLEANING THE AIR INTAKE SYSTEM OF A DIESEL VEHICLE

Applicant/Assignee: BG PRODUCTS, INC

Application No.: 11/780151   Filing Date: 19/Jul/2007

Abstract:

A device and method for cleaning the air-intake system of an EGR-valve-equipped diesel engine includes a dispersion component which mixes air and a liquid cleaning solution before delivering them to the air intake system of a running diesel engine. A main air intake is blocked and the EGR valve is removed and replaced with a coupler that receives the dispersion component, whereby a pressure drop is created. The pressure drop creates sufficient vacuum so that cleaner may be administered into the air-intake duct of the running engine. The cleaning solution is provided to the dispersion component under pressure supplied by a pressurized air source.

Priority: US2003-722302 Applic. Date: 2003-11-25; US20030478582P Applic. Date: 2003-06-13

Inventor: ERWIN HAROLD E [US]; AUGUSTUS RICHARD [US]

Title: FLAT-FOLD RESPIRATOR WITH MONOCOMPONENT FILTRATION/STIFFENING MONOLAYER

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/693186   Filing Date: 29/Mar/2007

Abstract:

A flat-fold respirator is made from a stiff filtration panel joined to the remainder of the respirator through at least one line of demarcation. The panel contains a porous monocomponent monolayer nonwoven web that contains charged intermingled continuous monocomponent polymeric fibers of the same polymeric composition and that has sufficient basis weight or inter-fiber bonding so that the web exhibits a Gurley Stiffness greater than 200 mg and the respirator exhibits less than 20 mm H2O pressure drop. The respirator may be formed without requiring additional stiffening layers, bicomponent fibers, or other reinforcement and can be flat-folded for storage. Scrap from the manufacturing process may be recycled to make additional stiff filtration panel web.

Priority: US2006-457899 Applic. Date: 2006-07-17; US2006-457906 Applic. Date: 2006-07-17; US2006-461128 Applic. Date: 2006-07-31; US2006-461136 Applic. Date: 2006-07-31; US2006-461145 Applic. Date: 2006-07-31; US2006-461192 Applic. Date: 2006-07-31; US2006-461201 Applic. Date: 2006-07-31

Inventor: ANGADJIVAND SEYED A [US]; SPRINGETT JAMES E [US]; BRANDNER JOHN M [US]; JONES MARVIN E [US]; FOX ANDREW R [US]; BERRIGAN MICHAEL R [US]; STELTER JOHN D [US]

Title: Methods for Reverse-Circulation Cementing in Subterranean Formations

Applicant/Assignee: HALLIBURTON ENERGY SERVICES HALLIBURTON ENERGY SERVICES, INC

Application No.: 11/862270   Filing Date: 27/Sep/2007

Abstract:

Methods and systems for reverse-circulation cementing in subterranean formations are provided. An example of a method is a method of cementing casing in a subterranean well bore, comprising inserting a casing into the well bore, the casing comprising a casing shoe

equipping the casing with a well head, and a casing inner diameter pressure indicator

flowing an equilibrium fluid into the well bore

flowing a cement composition into the well bore after the equilibrium fluid

determining from the well-bore pressure indicator when the well bore pressure has reached a desired value

discontinuing the flow of cement composition into the well bore upon determining that the well bore pressure has reached a desired value

and permitting the cement composition to set in the subterranean formation. Examples of systems include systems for cementing casing in a well bore.

Priority: US2004-973322 Applic. Date: 2004-10-26

Inventor: BADALAMENTI ANTHONY M [US]; BLANCHARD KARL W [US]; CROWDER MICHAEL G [US]; FAUL RONALD R [US]; GRIFFITH JAMES E [US]; ROGERS HENRY E [US]; TURTON SIMON [US]

Title: Systems for Reverse-Circulation Cementing in Subterranean Formations

Applicant/Assignee: HALLIBURTON ENERGY SERVICES

Application No.: 11/862300   Filing Date: 27/Sep/2007

Abstract:

Methods and systems for reverse-circulation cementing in subterranean formations are provided. An example of a method is a method of cementing casing in a subterranean well bore, comprising inserting a casing into the well bore, the casing comprising a casing shoe

equipping the casing with a well head, and a casing inner diameter pressure indicator

flowing an equilibrium fluid into the well bore

flowing a cement composition into the well bore after the equilibrium fluid

determining from the well-bore pressure indicator when the well bore pressure has reached a desired value

discontinuing the flow of cement composition into the well bore upon determining that the well bore pressure has reached a desired value

and permitting the cement composition to set in the subterranean formation. Examples of systems include systems for cementing casing in a well bore.

Priority: US2004-973322 Applic. Date: 2004-10-26

Inventor: BADALAMENTI ANTHONY M [US]; BLANCHARD KARL W [US]; CROWDER MICHAEL G [US]; FAUL RONALD R [US]; GRIFFITH JAMES E [US]; ROGERS HENRY E [US]; TURTON SIMON [US]

Title: Cleaning or care apparatus for medical or dental instruments

Applicant/Assignee: W&H DENTALWERK BURMOOS GMBH W&H DENTALWERK BUERMOOS GMBH

Application No.: 11/581901   Filing Date: 16/Oct/2006

Abstract:

A connecting device of a cleaning or care apparatus or a cleaning cassette comprises a blocking device which is movable between a first position and a second position and prevents loosening or displacement of an instrument that is to be cleaned during a cleaning or care operation because of the pressure exerted by the cleaning or care media. In some embodiments, a direct or indirect operative connection between the blocking device and a component of the cleaning or care apparatus or between the blocking device and at least a part of the cassette is provided, which transmits to the blocking device the force required to move the blocking device from the first position into the second position.

In other embodiments, the blocking device is moved from the first position into the second position by the action of the media in the line, e.g., either by direct contact with the media or indirectly through contact with another intermediate element.

Priority: EP20050022643 Applic. Date: 2005-10-18

Inventor: HELFENBEIN GERALD [AT]; SCHAFFARZICK DANIEL [AT]

Title: Methods of Making Compositions Comprising Films

Applicant/Assignee:

Application No.: 11/457610   Filing Date: 14/Jul/2006

Abstract:

The invention relates to methods of making films having active ingredients. A film that is substantially free of active ingredient is introduced into a medium comprising an active ingredient. At least a portion of the active ingredient is transferred from the medium to the film. The films can be used in a variety of applications, including oral care, personal care, cleansing and/or home care compositions.

Priority:

Inventor: BOYD THOMAS J [US]; DILLON RENSL [US]; MILLER JEFFREY M [US]; VISCIO DAVID B [US]; GAFFAR ABDUL [US]

Title: DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/778381   Filing Date: 16/Jul/2007

Abstract:

Polymerizable compositions and methods are provided that include an ethylenically unsaturated compound and an arylsulfinate salt. The polymerizable compositions are useful as hardenable dental compositions.

Priority: US2003-672814 Applic. Date: 2003-09-26

Inventor: FALSAFI AFSHIN [US]; KALGUTKAR RAJDEEP S [US]; OXMAN JOEL D [US]

Title: Modulators of muscarinic receptors

Applicant/Assignee:

Application No.: 11/644124   Filing Date: 22/Dec/2006

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20050753187P Applic. Date: 2005-12-22

Inventor: MAKINGS LEWIS R [US]; BLANCO MIGUEL G [US]; HURLEY DENNIS J [US]; DRUTU IOANA [US]; RAFFAI GABRIEL [US]; BERGERON DANIELE M [US]; NAKATANI AKIKO [US]; TERMIN ANDREAS P [US]; SILINA ALINA [US]

Title: SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/864987   Filing Date: 29/Sep/2007

Abstract:

Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US2006-345926 Applic. Date: 2006-02-01; US2003-347210 Applic. Date: 2003-01-21; US20020349920P Applic. Date: 2002-01-17; US20020350527P Applic. Date: 2002-01-22

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; BLUM CHARLES A [US]; BRIELMANN HARRY [US]; CALDWELL TIMOTHY M [US]; DE LOMBAERT STEPHANE [US]; HODGETTS KEVIN J [US]; ZHENG XIAOZHANG [US]; KRAUSE JAMES E [US]; HERZBERG URI [US]; YOON TAEYOUNG [US]

Title: METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT

Applicant/Assignee:

Application No.: 11/626324   Filing Date: 23/Jan/2007

Abstract:

The present invention is directed to methods for developing one or more drugs for one or more targeted therapies and compositions derived therefrom. In accordance with one aspect of the present invention, combinatorial chemistry techniques for use with high throughput screening techniques for identifying small molecule affinity and/or activity interactions are avoided by instead utilizing the natural mechanisms of antigen response to effect a massively parallel screening of naturally occurring molecules against an antigen. Other aspects of the invention provide compositions derived therefrom as well as therapeutic methods of use for the compounds.

Priority: US20060761123P Applic. Date: 2006-01-23

Inventor: ERRICO JOSEPH P [US]; MUGRAGE BENJAMIN B [US]; TURCHI IGNATIUS J [US]

Title: ODOR ABSORBING SYSTEM AND METHOD

Applicant/Assignee: SUNBURST COMPANIES, INC

Application No.: 11/858617   Filing Date: 20/Sep/2007

Abstract:

An odor absorbing system includes a head covering article of clothing configured to be worn by a person. The head covering article of clothing includes a base layer comprising a cap section configured to substantially cover a head of the person wearing the article of clothing. An odor absorbing insert is removable attachable to the article of clothing.

Priority: US2007-881083 Applic. Date: 2007-07-25; US2004-024510 Applic. Date: 2004-12-29; US20040580303P Applic. Date: 2004-06-16

Inventor: NEWMAN ANTHONY E [US]

Title: Formed materials and strips used in fuel tanks and to prevent explosive reactions

Applicant/Assignee: PROTECHT SOLUTIONS SA

Application No.: 11/730919   Filing Date: 04/Apr/2007

Abstract:

The invention relates to a stamped or braided form of a solid material or foil that can be inserted into a tank or container, for example to prevent an explosion of fuel inside the tank. Various combinations of materials can be used to produce the forms and braids. In a preferred embodiment, two or more stamped, helical forms of a metal foil material are interlocked or linked together, and a wire or fiber is placed at least partially in the center of one of the helical forms. This structure presents advantageous properties when used in fuel tanks, and resists deformation. In addition, certain forms or structures can be designed and used so they can be easily removed from the container or tank.

Priority: WO2005CH00576 Applic. Date: 2005-10-04; US20040615026P Applic. Date: 2004-10-04

Inventor: KERBRAT RENAUD [CH]; JEBSEN JAN H [CH]

Title: Method and Device for Releasing Flavor and Odor Substances

Applicant/Assignee:

Application No.: 10/591648   Filing Date: 27/Jun/2007

Abstract:

A device for releasing substances into the mouth, that comprises an intra-oral pacifier provided with a sucking element that partially or fully occupies the mouth of a user. The sucking element is used for releasing flavor substances and is made from materials in the natural or unnatural latex family. An adequate amount of the substances is provided inside, or on the pacifier. The substances may include some nicotine for smoking cessation, antibacterial materials for curing intra-oral diseases, or flavor or odor substances.

Priority: IL20040160753 Applic. Date: 2004-03-04; WO2005IL00252 Applic. Date: 2005-03-03

Inventor: CHAZOT AHRON [IL]

Title: Urinalysis screening device

Applicant/Assignee:

Application No.: 11/582762   Filing Date: 19/Oct/2006

Abstract:

A urinalysis screening device is disclosed that comprises a container, a cap for the container which seals in the urine sample, and an assay assembly that fits into the container. The assay assembly contains a plurality of diagnostic strips that enables the urine to be analyzed for various substances

Priority: US20060832824P Applic. Date: 2006-07-22

Inventor: JOHNSON PAUL K [US]; COOPER CAROLYN J [US]; KOLAR SARAH [US]; MORPHEW ROBERT [US]; STRASSER RICHARD [US]

Title: DENTAL IMPLANT AND METHOD FOR MAKING AND INSTALLING SAME

Applicant/Assignee:

Application No.: 11/832213   Filing Date: 01/Aug/2007

Abstract:

A method for making a dental implant by obtaining images of the tooth pre-atraumatic tooth extraction and post extraction and using those images to computer generate and mill a titanium replacement implant employing CAD/CAM equipment. The implant includes a scalloped neck interface similar to the replaced tooth's scalloped cementoenamel junction, a polished neck area between a root portion and a crown portion, and the numeral for the tooth number imprinted on the implant's facial surface. Chevron retention fins are provided on the root portion for engaging the bone of the tooth socket or osteotomy when the implant is tapped into position. Retention grooves are provided on the crown portion to which a provisional crown is cemented slightly out of occlusion at the time the implant is placed. The provisional crown will be replaced with a permanent crown after osteointegration of the implant has occurred.

Priority: US2004-996118 Applic. Date: 2004-11-23

Inventor: MOUNT K T [US]

Title: Method and device for cleaning teeth

Applicant/Assignee:

Application No.: 11/888385   Filing Date: 01/Aug/2007

Abstract:

The invention is directed to a method and a device for cleaning teeth wherein a variety of cleaning tools are coupled to a common handle section for the individual cleaning of teeth. It relates in particular to a handle section of an electric dental cleaning device, with a coupling section for coupling various cleaning tools thereto, as well as said cleaning tools. According to the invention the handle section detects a coding provided on the respective cleaning tool attached. In dependence upon the respective coding detected, various functions of the dental cleaning device are controlled.

Priority: US2004-872016 Applic. Date: 2004-06-18; US2003-662237 Applic. Date: 2003-09-15

Inventor: HILSCHER ALEXANDER [DE]; MANNEBACH HORST [DE]; REICK HANSJORG [DE]; SCHWARZ-HARTMANN ARMIN [DE]; TRAWINSKI PETER [DE]; STRATMANN MARTIN [DE]; VORBECK WOLFGANG [DE]

Title: Anesthesia monitor, capacitance nanosensors and dynamic sensor sampling method

Applicant/Assignee:

Application No.: 11/588845   Filing Date: 26/Oct/2006

Abstract:

Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such as anesthesia gases, CO2 and the like in human breath. An integrated monitor system and disposable sensor unit is described which permits a number of different anesthetic agents to be identified and monitored, as well as concurrent monitoring of other breath species, such as CO2. The sensor unit may be configured to be compact, light weight, and inexpensive. Wireless embodiments provide such enhancements as remote monitoring. A simulator system for modeling the contents and conditions of human inhalation and exhalation with a selected mixture of a treatment agent is also described, particularly suited to the testing of sensors to be used in airway sampling.

Priority: US2006-488456 Applic. Date: 2006-07-18; US20050730905P Applic. Date: 2005-10-27; US20060773138P Applic. Date: 2006-02-13; US20050748834P Applic. Date: 2005-12-09

Inventor: GABRIEL JEAN-CHRISTOPHE P [US]; JOSHI VIKRAM [US]; PASSMORE JOHN L [US]; SKARUPO SERGEI [US]; STAR ALEXANDER [US]; VALCKE CHRISTIAN [US]

Title: Methods and systems for management of information related to the appearance of an object

Applicant/Assignee:

Application No.: 11/902839   Filing Date: 26/Sep/2007

Abstract:

The present invention provides an improved system for measuring the appearance of an object, that improves upon the prior art systems by employing a digital CMOS camera and a variety of features attendant thereto, provides an improved calibration system, an improved quality control system, an improved tooth whitening system, and an improved crown design system.

Priority: CA20012343672 Applic. Date: 2001-04-11; CA20022372852 Applic. Date: 2002-02-19; US2003-682302 Applic. Date: 2003-10-10; WO2002IB02547 Applic. Date: 2002-04-11

Inventor: WHAITE PETER [CA]; TREMBLAY PIERRE-JULES [CA]

Title: Dental cleaning device

Applicant/Assignee:

Application No.: 11/888287   Filing Date: 31/Jul/2007

Abstract:

An electric toothbrush with a removable brush section having a transponder communicating with a handle portion of the toothbrush via a non-contacting inductive coupling.

Priority: DE20011059395 Applic. Date: 2001-12-04; US2004-872075 Applic. Date: 2004-06-18; US2002-241274 Applic. Date: 2002-09-10; US2004-872016 Applic. Date: 2004-06-18; US2003-662237 Applic. Date: 2003-09-15; WO2001EP02844 Applic. Date: 2001-03-14; US2004-871469 Applic. Date: 2004-06-18; US2001-811080 Applic. Date: 2001-03-16

Inventor: HILSCHER ALEXANDER [DE]; REICK HANSJORG [DE]; STRATMANN MARTIN [DE]; TRAWINSKI PETER [DE]; VORBECK WOLFGANG [DE]; SCHWARZ-HARTMANN ARMIN [DE]

Title: Dental Stick

Applicant/Assignee:

Application No.: 11/596502   Filing Date: 18/May/2004

Abstract:

The invention relates to medicine, in particular to dentistry. The inventive dental stick comprises a holder ( 1 ) provided with oppositely deflected massaging ( 2 ) and cleaning ( 3 ) elements tapered towards the ends thereof. Said holder is bent so that a fold is formed in the middle section thereof with two symmetrical segments ( 4 ) and ( 5 ) oppositely shifted with respect to a symmetry axis ( 6 ). Said symmetrical segments of the holder ( 1 ) have round cross sections ( 7 ) reducing away from the middle of the holder towards the massaging elements ( 2 ). Said massaging ( 2 ) and cleaning ( 3 ) elements are formed by two flat faces ( 8 ) and ( 9 ) which are perpendicular to the holder axis plane. The massaging elements are deflected to the sides which are opposite to the shift of the holder symmetrical segments with respect to the symmetry axis ( 6 ). The cleaning elements are provided with roundish-shaped extensions oppositely oriented with respect to the holder axis plane. The surfaces of the massaging elements which are opposite to the extension direction of the corresponding cleaning element are wave-shaped.

Priority: WO2004RU00189 Applic. Date: 2004-05-18

Inventor: IZMAYLOV VIKTOR I [RU]

Title: WAVELENGTH-TUNABLE LIGHT GENERATOR AND OPTICAL COHERENCE TOMOGRAPHY DEVICE

Applicant/Assignee: SCHOOL JURIDICAL PERSON KITASATO GAKUEN NIPPON TELEGRAPH AND TELEPHONE CORPORATION SCHOOL JURIDICAL PERSON KITASATO INSTITUTE

Application No.: 11/867736   Filing Date: 05/Oct/2007

Abstract:

The present invention provides an OCT technique that permits tomographic observation of a biological body parts that is difficult to restrain and also provides a tomographic observation technique for the observation of a constrainable part that does not require constraint and remove the burden from biological body. A wavelength-tunable light generator (wavelength-tunable light source) is employed as the light source of the optical coherence tomography device. The wavelength-tunable light generator has a wave number tunable range width of at least 4.7x10<-2 >mum<-1 >and an emitted-light frequency width of no more than 13 GHz, for example, and includes means capable of changing the wave number stepwise at wave number intervals of no more than 3.1x10<-4 >mum<-1 >and time intervals of no more than 530 mus.

Priority: JP20030335207 Applic. Date: 2003-09-26; JP20040202956 Applic. Date: 2004-07-09; JP20040202957 Applic. Date: 2004-07-09; US2004-573113 Applic. Date: 2004-09-22; WO2004JP14302 Applic. Date: 2004-09-22

Inventor: SHIMIZU KIMIYA [JP]; OHBAYASHI KOHJI [JP]; AMANO TAKUJI [JP]; HIRO-OKA HIDEAKI [JP]; CHOI DONGHAK [JP]; FURUKAWA HIROYUKI [JP]; NAKANISHI MOTOI [JP]; KANO FUMIYOSHI [JP]; MIYAZAWA TAKEO [JP]; YOSHIMURA RYOKO [JP]

Title: LED-POWERED DENTAL OPERATORY LIGHT

Applicant/Assignee: PELTON & CRANE

Application No.: 11/867876   Filing Date: 05/Oct/2007

Abstract:

A lamp assembly adapted to cast shadow-free illumination over an area. Typically, a lamp assembly includes a plurality of light modules that are disposed in a spaced apart relationship over an area. The lamp assembly can be arranged to focus light from the lamp to a central area of illumination of high intensity, with significantly reduced intensity illumination outside the central area.

Priority: US2005-120170 Applic. Date: 2005-05-02

Inventor: LOCKAMY H T [US]; UNSWORTH AUSTIN E [US]

Title: DENTAL BLEACHING COMPOSITIONS HAVING LONG-TERM RHEOLOGICAL STABILITY AND DEVICES, KITS AND METHODS THAT UTILIZE SUCH COMPOSITIONS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/460016   Filing Date: 26/Jul/2006

Abstract:

Dental bleaching compositions include a dental bleaching agent, a generally linear high molecular weight (i.e., greater than about 500,000) polyvinyl pyrrolidone (PVP) and/or polyethylene oxide (PEO) tissue adhesion agent included in amount that imparts a high level of adhesiveness, a rheology-modifying agent such as fumed silica or fumed alumina that reduces or eliminates stringiness otherwise caused by the high molecular weight PVP and/or PEO, and a solvent or carrier. Dental bleaching compositions may include carboxypolymethylene instead of or in addition to PVP and/or PEO, wherein the fumed silica or fumed alumina increases long-term rheological stability even in the presence of a high concentration of dental bleaching agent. Dental treatment devices including a barrier layer and a quantity of the dental bleaching composition positioned adjacent to the barrier layer.

Priority:

Inventor: ALLRED PETER M [US]

Title: Oral care formulations with hydrogen peroxide and lycopene

Applicant/Assignee: DR. NICK'S WHITE & HEALTHY, LLC

Application No.: 11/491187   Filing Date: 24/Jul/2006

Abstract:

A toothpaste formulation is disclosed which comprises hydrogen peroxide

and cetylpyridinium chloride, and wherein the hydrogen peroxide and the cetylpyridinium chloride have been combined in the toothpaste formulation for not more than about seven minutes prior to administration to an individual. A mouth rinse formulation is disclosed which comprises hydrogen peroxide

and cetylpyridinium chloride, and wherein the hydrogen peroxide and the cetylpyridinium chloride have been combined in the mouth rinse formulation for not more than about seven minutes prior to administration to an individual. A whitening gel formulation is disclosed which comprises hydrogen peroxide

and pH adjuster, and wherein the hydrogen peroxide and the pH adjuster have been combined in the whitening gel formulation for not more than about seven minutes prior to administration to an individual. The toothpaste formulation, the mouth rinse formulation, and the whitening gel formulation further comprise lycopene.

Priority:

Inventor: KAVOUKLIS NICHOLAS M [US]; GAUDREAULT ROSEMARY A [US]

Title: METHODS FOR TREATING AND PREVENTING MUCOSITIS

Applicant/Assignee:

Application No.: 11/829138   Filing Date: 27/Jul/2007

Abstract:

Methods for treating and preventing mucositis, in particular mucositis following the administration of chemotherapy drugs or a combination of said drugs with radiotherapy, are disclosed herein. More specifically, disclosed herein is the administration of a therapeutically effective amount of at least one of an anthocyanoside, a proanthocyanidin, or an extract containing at least one of an anthocyanoside or a proanthocyanidin for the treatment or prevention of mucositis. The therapeutically effective amount of the anthocyanoside, proanthocyanidin or extract can be administered alone or in combination with a therapeutically effective amount of at least one of an anti-inflammatory agent, immunomodulating agent, analgesic, antimicrobial agent or antifungal agent. Also disclosed herein are pharmaceutical compositions for treating and preventing mucositis.

Priority: EP20060015732 Applic. Date: 2006-07-28

Inventor: BOMBARDELLI EZIO [IT]; MORAZZONI PAOLO [IT]

Title: Dental Model Tray And Associated Articulator

Applicant/Assignee:

Application No.: 10/589386   Filing Date: 26/Jan/2005

Abstract:

A dental model tray ( 12 ) for use in forming a dental model has a rigid bottom wall ( 16 ) and a relatively thin side wall ( 17 ) extending upwardly from the perimeter of the bottom wall ( 16 ) to form an open-topped cavity which is adapted to receive the dental casting material. The bottom wall ( 16 ) and the side wall ( 17 ) are formed integrally of polymeric material with the side wall ( 17 ) being joined to or attached to the bottom wall ( 16 ) by a thin membrane-like connector member ( 19 ) that is formed integrally with the perimeter bottom wall ( 16 ) and a lower side edge of the side wall ( 17 ). The connector member ( 19 ) is frangible and easily broken so that the side wall ( 17 ) can be torn away from the base and discarded after dental casting material has hardened in the cavity formed by the side wall ( 17 ).

Priority: US20040546406P Applic. Date: 2004-02-20; WO2005US03105 Applic. Date: 2005-01-26

Inventor: GARLAND JAMES K [US]

Title: Methods to identify biologically active agents and synergistic combinations

Applicant/Assignee: SYNERGY BIOSYSTEMS LTD

Application No.: 11/893401   Filing Date: 17/Aug/2007

Abstract:

Methods are described using a particular type of assay system, the Multi-Pathway High Throughput Assay, in conjunction with a novel experimental strategy, whereby repeated cycles of experiments result in the identification of the most effective synergistic combinations of potential active agents from a library of materials. The novel experimental strategy not only requires far fewer total experiments than would be required using conventional discovery strategies but also maximizes the probability of finding highly synergistic combinations through the principle of multiple-pathway intervention.

Priority: US2004-807811 Applic. Date: 2004-03-24; US20030457859P Applic. Date: 2003-03-26; US20030457860P Applic. Date: 2003-03-26; US20030457861P Applic. Date: 2003-03-26; US20030483564P Applic. Date: 2003-06-28

Inventor: SCOTT IAN R [GB]

Title: PEPTIDES EFFECTIVE IN THE TREATMENT OF TUMORS AND OTHER CONDITIONS REQUIRING THE REMOVAL OR DESTRUCTION OF CELLS

Applicant/Assignee:

Application No.: 11/756452   Filing Date: 31/May/2007

Abstract:

This application discloses compositions and methods for treating conditions requiring removal or destruction of harmful or unwanted cells in a patient, such as benign and malignant tumors, using compounds containing or based on multimeric peptides.

Priority: US20060820839P Applic. Date: 2006-07-31

Inventor: AVERBACK PAUL [CA]; GEMMELL JACK [CA]

Title: COLD MENTHOL RECEPTOR-1 ANTAGONISTS

Applicant/Assignee:

Application No.: 11/746318   Filing Date: 09/May/2007

Abstract:

The invention is directed to TRPM8 antagonists of Formula (I). More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating TRPM8-mediated disorders. Pharmaceutical and veterinary compositions and methods of treating pain and various other disease states or conditions using compounds of the invention are also described.

Priority: US20060799275P Applic. Date: 2006-05-10; US20070915527P Applic. Date: 2007-05-02

Inventor: COLBURN RAYMOND W [US]; DAX SCOTT L [US]; FLORES CHRISTOPHER [US]; MATTHEWS JAY [US]; QIN NING [US]; REANY LAURA [US]; TELEHA CHRISTOPHER [US]; YOUNGMAN MARK A [US]

Title: Heterocyclic derivatives as modulators of ion channels

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 11/643622   Filing Date: 21/Dec/2006

Abstract:

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Priority: US20050752926P Applic. Date: 2005-12-21; US20060791181P Applic. Date: 2006-04-11; US20060799797P Applic. Date: 2006-05-12; US20060839444P Applic. Date: 2006-08-23

Inventor: MARTINBOROUGH ESTHER [US]; FANNING LEV T [US]; SHETH URVI [US]; WILSON DEAN [US]; TERMIN ANDREAS [US]; NEUBERT TIMOTHY [US]; ZIMMERMANN NICOLE [US]; KNOLL TARA [US]; WHITNEY TARA [US]; KAWATKAR ARATI [US]; LEHSTEN DANIELLE [US]; STAMOS DEAN [US]; ZHOU JINGLAN [US]; ARUMUGAM VIJAYALAKSMI [US]; GUTIERREZ COREY [US]

Title: Methods and compositions employing bicifadine for the treatment of acute pain, chronic pain, and symptoms of neuropathic disorders

Applicant/Assignee:

Application No.: 11/260887   Filing Date: 26/Oct/2005

Abstract:

Methods and compositions are provided for formulating and administering bicifadine and related compounds to treat acute pain, chronic pain, and symptoms associated with neuropathic disorders.

Priority: US2003-621435 Applic. Date: 2003-07-17; US20020399852P Applic. Date: 2002-07-31

Inventor: LIPPA ARNOLD S [US]; STERN WARREN [US]; CODD JANET [IE]; BOLAND BRIAN [IE]; JOHNSON LIM [US]

Title: Therapeutic Molecules and Methods for Generating and/or Selecting Same

Applicant/Assignee:

Application No.: 10/588687   Filing Date: 03/Feb/2005

Abstract:

The present invention relates generally to therapeutic molecules useful for inducing apoptosis of particular cells such as, but not limited to, cancer cells and methods for generating and/or selecting same. The present invention further provides methods for inducing apoptosis of cells such as cancer cells and pharmaceutical compositions useful for same. The present invention further provides methods for generating or selecting therapeutic agents capable of inducing apoptosis of particular cells by the selective inhibition of pro-survival proteins. The present invention further provides a computational approach to therapeutic molecule design based on structure-binding characteristics.

Priority: AU20040900562 Applic. Date: 2004-02-06; WO2005AU00140 Applic. Date: 2005-02-03

Inventor: HUANG DAVID C S [AU]; COLMAN PETER M [AU]; DAY CATHERINE L [NZ]; ADAMS JERRY M [AU]; CHEN LIN [AU]; WILLIS SIMON N [AU]; WEI ANDREW [AU]; SMITH BRIAN J [AU]; HINDS MARK G [AU]

Title: Dental cleaning device

Applicant/Assignee:

Application No.: 11/888189   Filing Date: 31/Jul/2007

Abstract:

An electric toothbrush with a removable brush section having a transponder communicating with a handle portion of the toothbrush via a non-contacting inductive coupling.

Priority: DE20011059395 Applic. Date: 2001-12-04; US2004-872075 Applic. Date: 2004-06-18; US2002-241274 Applic. Date: 2002-09-10; US2004-872016 Applic. Date: 2004-06-18; US2003-662237 Applic. Date: 2003-09-15; WO2001EP02844 Applic. Date: 2001-03-14; US2004-871469 Applic. Date: 2004-06-18; US2001-811080 Applic. Date: 2001-03-16

Inventor: HILSCHER ALEXANDER [DE]; REICK HANSJORG [DE]; STRATMANN MARTIN [DE]; TRAWINSKI PETER [DE]; VORBECK WOLFGANG [DE]; SCHWARZ-HARTMANN ARMIN [DE]

Title: Training toothbrush with audio

Applicant/Assignee:

Application No.: 11/810624   Filing Date: 06/Jun/2007

Abstract:

A toothbrush device used for a unique teaching method for proper teeth brushing techniques by means of prerecorded audio commands emanating from the handle of the toothbrush. The toothbrush with audio is a product that is designed to easily and quickly provide a new and unique motivation for young children to brush their teeth correctly. This special toothbrush combined with an integral audio device to encourage and coach children on proper tooth brushing habits. The configuration comprises a handle that is slightly larger than a conventional toothbrush and the handle contains a waterproof speaker, a power switch, and a battery compartment. The extension neck and bristle are similar to conventional toothbrushes.

Priority: US20060812931P Applic. Date: 2006-06-13

Inventor: BATTHAUER JULIE A [US]

Title: Device and Method for Washing Nasal Passages

Applicant/Assignee: MED-SYSTEMS, INC

Application No.: 11/831794   Filing Date: 31/Jul/2007

Abstract:

A nasal passage washing device includes a pliable body including an open top

and an applicator cap removably attached to the pliable body to cover and uncover the open top. The applicator cap includes an applicator tip having a substantially frustoconical configuration sized and shaped for receipt at least partially within a nostril of a user for sealing engagement therewith, the applicator tip including a hole to transfer washing solution there through, a washing solution transfer tube in communication with the hole of the applicator tip and a bottom of an inside of the pliable body to transfer washing solution from the bottom of the inside of the pliable body to the hole of the applicator tip, and a one-way air valve that only allows air flow into the pliable body through the one-way air valve and does not allow air flow and washing solution flow out of the pliable body through the one-way air valve.

Priority: US20060821517P Applic. Date: 2006-08-04

Inventor: HARLAN JEFFREY [US]; HEATLEY DIANE [US]; GALLO DAVID [US]

Title: Smokeless Tobacco Composition

Applicant/Assignee: R. J. REYNOLDS TOBACCO COMPANY

Application No.: 11/781604   Filing Date: 23/Jul/2007

Abstract:

A smokeless tobacco product configured for insertion into the mouth of a user of the product is provided, the tobacco product including a water-permeable pouch containing a tobacco formulation, the tobacco formulation including a tobacco material and a plurality of microcapsules dispersed within the tobacco material, the plurality of microcapsules including an outer shell encapsulating an internal payload. The internal payload may include an additive such as water, flavorants, binders, colorants, pH adjusters, buffering agents, fillers, disintegration aids, humectants, antioxidants, oral care ingredients, preservatives, additives derived from herbal or botanical sources, and mixtures thereof.

Microencapsulated flavorants include tobacco-containing flavorants, such as tobacco extracts or a particulate tobacco material, sweeteners (e.g., sweeteners containing neotame), and vanillin (optionally in a complexed form).

Priority: US2006-351919 Applic. Date: 2006-02-10

Inventor: DUBE MICHAEL F [US]; CANTRELL DANIEL V [US]; MUA JOHN-PAUL [US]; HOLTON DARRELL E JR [US]; STOKES CYNTHIA S [US]; FIGLAR JAMES N [US]

Title: Multi-component filter providing multiple flavour enhancement

Applicant/Assignee: PHILIP MORRIS USA, INC PHILIP MORRIS USA INC

Application No.: 11/882115   Filing Date: 30/Jul/2007

Abstract:

A multi-component filter for a smoking article comprises: a mouth end segment

a first flavour release segment comprising plant leaf upstream of the mouth end segment

and a second flavour release segment comprising filtration material and a flavourant upstream of the first flavour release segment. The resistance to draw of the second flavour release segment is greater than the resistance to draw of the first flavour release segment and the resistance to draw of the second flavour release segment is greater than the resistance to draw of the mouth end segment. The multi-component filter preferably further comprises a rod end segment comprising filtration material upstream of the second flavour release segment, which has a lower resistance to draw than the second flavour release segment.

Priority: EP20060254102 Applic. Date: 2006-08-04

Inventor: SEITERT HUGUES [CH]; GAWAD AHMED [CH]; LEKILI LEVENT [CH]; KUERSTEINER CHARLES [CH]

Title: Power dental flosser

Applicant/Assignee:

Application No.: 11/474600   Filing Date: 26/Jun/2006

Abstract:

The present invention of the Power Dental Flosser uses a looped dental floss driven by a small electric motor to provide a continuous cleaning motion for a better teeth cleaning experience. At least one of the spool is capable of rotating with an attached tooth brush or with a tooth polishing what could be rotated in and out. The disposable dental loop is strong, made from naturally waxy polymer material preferably from a biodegradable thin-gauged high-density polyethylene (HDPE) or similar material.

Priority:

Inventor: EGERESI ZOLTAN [US]

Title: Device to alternately supply a fluid to an analyzer

Applicant/Assignee:

Application No.: 11/811913   Filing Date: 12/Jun/2007

Abstract:

Apparatus and methods for supplying a portion of a fluid stream and, alternately, a fluid of known composition and concentration to an analyzer are provided. The fluid stream is directed through a series of connected chambers formed in an integral housing. A sampling needle has an inlet in one of the chambers and an outlet in fluid communication with the analyzer. When desired, a tube or vial containing a known fluid may be inserted into a chamber containing the sampling needle, so that the known fluid will be supplied to the analyzer. A second needle provides ventilation to the vial to prevent the formation of a vacuum as the known fluid is drained from the vial.

Priority: US2003-352516 Applic. Date: 2003-01-28; US2001-894313 Applic. Date: 2001-06-27; US1999-368990 Applic. Date: 1999-08-05; US1998-191610 Applic. Date: 1998-11-13; US1996-629609 Applic. Date: 1996-04-09

Inventor: GODEC RICHARD D [US]; SILVESTER FRANK J [US]; BATEMAN BLAINE R [US]

Title: Dental Composition Containing an Epoxy Functional Carbosilane Compound

Applicant/Assignee: 3M ESPE AG

Application No.: 11/572062   Filing Date: 14/Jul/2004

Abstract:

The present invention relates to a dental composition comprising least one carbosilane compound comprising at least one Si-Aryl bond, at least one silicon atom, no Si-Oxygen bond, at least one aliphatic epoxy moiety, wherein said carbosilane compound has no glycidyl ether moieties

and an initiator, optionally filler and optionally additive components selected from the group of modifiers, stabilizers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.

Priority: WO2004EP07791 Applic. Date: 2004-07-14

Inventor: ECKERT ADRIAN S [DE]; BISSINGER PETER [DE]; DEDE KARSTEN [DE]; KLETTKE THOMAS [DE]

Title: Oral anti-calculus compositions and methods of use thereof

Applicant/Assignee: TECHNOLOGY & MARKETING CONSULTING

Application No.: 11/255248   Filing Date: 21/Oct/2005

Abstract:

The present invention provides anticalculus oral compositions containing a plant oil mixture comprising a major oil constituent and a minor oil constituent in a proportion of at least 10/1 respectively. The major oil constituent comprises an edible vegetable oil and the minor oil consitutent comprises emulsifying oil, flavoring oil, antiseptic oil, anti-inflammatory oil, or a combination thereof.

Priority:

Inventor: LAALI MOEIN [DE]

Title: BARRIERS FOR POLYMERIC COATINGS

Applicant/Assignee: SURMODICS, INC

Application No.: 11/873747   Filing Date: 17/Oct/2007

Abstract:

A barrier adapted to be positioned between a first surface provided in the form of a polymeric, bioactive agent-containing coating upon a medical device, and a second surface provided by another material positioned in apposition, and preferably moveable apposition, to the first surface. The barrier, as provided by block copolymers or photoderivatized polymers, provides protection to the polymeric composition from mechanical damage and/or delamination during fabrication, storage, delivery or deployment, and/or residence of the device within the body. A combination that includes a medical device, such as a stent, and another device, such as a surrounding sheath or internal expandable balloon, between which is positioned a barrier of the type described.

Priority: US2002-313234 Applic. Date: 2002-12-06

Inventor: LAWIN LAURIE R [US]; BOUCHA-RAYLE MICHELLE C [US]; KLOKE TIMOTHY M [US]

Title: Beta-Substituted Tetrahdropyrana (On) S And Method For The Synthesis And The Use Thereof

Applicant/Assignee: V. MANE FILS

Application No.: 11/659501   Filing Date: 05/Aug/2005

Abstract:

The invention relates, in particular to a tetrahydropyran(on) compound which is substituted in position beta with respect to a cycle oxygen of formula (I), wherein a substituent R is a linear alkyl radical in C2:C10 including, (CH3)2CH- or C6H5-(CH2)m-, with m=0 or 1, or formula (II), wherein A is -CH2- or -CO-, in the form of an odorant and to a method for the synthesis thereof by reducing oxo-ester. The use of the inventive compound in composition such as perfumery compositions in the ordinary sense of the term i.e. topic, in particular cosmetic compositions and care products.

Priority: FR20040008729 Applic. Date: 2004-08-06; WO2005FR02038 Applic. Date: 2005-08-05

Inventor: MANE JEAN [FR]; CHANOT JEAN-JACQUES [FR]; SCHROEDER MARTIN [FR]

Title: Modulators of muscarinic receptors

Applicant/Assignee:

Application No.: 11/823762   Filing Date: 28/Jun/2007

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20060817385P Applic. Date: 2006-06-29

Inventor: BANDARAGE UPUL K [US]; XU JINWANG [US]; DAVIES ROBERT J [US]; CHARIFSON PAUL S [US]; ARIMOTO RIEKO [US]

Title: Dental Cleaning Substance Medium, Packaging, and Device

Applicant/Assignee:

Application No.: 11/836134   Filing Date: 08/Aug/2007

Abstract:

A single-use portion of dental cleaning substance provided in a tidy, convenient, and hygienic manner. The single-use portion of dental cleaning substance may be provided in a solid form and may be utilized via a traditional toothbrush (electronic or standard) or by use of a specific device.

Priority: US20060822095P Applic. Date: 2006-08-11; US20070911585P Applic. Date: 2007-04-13

Inventor: JALILI REZA [US]

Title: Modified interferon-beta (IFN-beta) polypeptides

Applicant/Assignee:

Application No.: 11/729267   Filing Date: 27/Mar/2007

Abstract:

Provided are modified interferon-beta polypeptides and nucleic acid molecules encoding modified interferon-beta polypeptides and formulations containing the polypeptides and/or nucleic acid molecules. The modified polypeptides exhibit increased protein stability, including increased resistance to proteases. Also provided are methods of treatment by administering modified interferon-beta polypeptides.

Priority: US20060787208P Applic. Date: 2006-03-28

Inventor: GUYON THIERRY [FR]; BORRELLY GILLES [FR]; DRITTANTI LILA [FR]; VEGA MANUEL [FR]

Title: Tetracycline Package Formulations

Applicant/Assignee:

Application No.: 11/763860   Filing Date: 15/Jun/2007

Abstract:

The invention provides a rapidly disintegrating and dissolving multilayer tablet comprising at least a tetracycline in a first layer, a buffer in a second layer, and optionally, an inert layer separating the first and second layers. The multilayer tablets of the invention are useful for treating or preventing mucositis, when administered topically to the oral cavity.

Priority: US20060813949P Applic. Date: 2006-06-15

Inventor: SMITH ALEXANDER D [US]; COBB JOE [US]; BETTIS JOHN [US]; STAGNER WILLIAM C [US]; GOLD BRAD [US]

Title: Media

Applicant/Assignee: BRIGHTWATER ENGINEERING LIMITED

Application No.: 11/662049   Filing Date: 08/Sep/2005

Abstract:

Plastic particles of a selected one of various shapes are usage in a floating media bed of a biological aerated flooded filter. They may be manufactured by injection moulding or by an extrusion-and-chopping method comprising advancing molten plastics through a channel-form extrusion die slot 30, cooling the extruded plastics in water, and chopping-off transversely by a die head face cutter 34 pieces of the cooled channel-form plastics, the distribution of the volumetric rate of flow of the plastics over the outlet mouth of the die slot 30 being such that the external surface of the base of the cooled channel-form plastics is longitudinally convex.

Priority: GB20040019901 Applic. Date: 2004-09-08; WO2005GB03460 Applic. Date: 2005-09-08

Inventor: CANTWELL ALAN D C [GB]

Title: Methods and kits for early stage caries detection

Applicant/Assignee:

Application No.: 11/787158   Filing Date: 13/Apr/2007

Abstract:

Methods and kits are provided for identifying very early stage carious lesions using a detectable probe that binds to the lesion.

Priority: US20060792768P Applic. Date: 2006-04-18; US20060819135P Applic. Date: 2006-07-07; US20070901421P Applic. Date: 2007-02-15; US20060850922P Applic. Date: 2006-10-11

Inventor: NAGAI SHIGEMI [US]

Title: Dental finishing, sanding and/or polishing floss

Applicant/Assignee:

Application No.: 11/891820   Filing Date: 13/Aug/2007

Abstract:

An abrading dental floss is characterized by dental floss having a dental abrasive on at least a portion thereof suitable for polishing, sanding and/or finishing dental restorative material such as dental resin. The dental abrading material is impregnated into or provided onto the dental floss. In one form, the dental abrading floss has an abrading/abrasion/polishing/finishing/sanding section situated between lengths of the dental floss. The abrading polishing section may be formed of an alternating pattern of non-abrasive portions and abrasive portions along a length of the floss. The abrasive portions may be of a single grit or texture of the dental abrasive or may be of different grits of the dental abrasive. In another form, the dental abrading floss has a single grit of a dental abrasive along its entire length. In yet another form, the dental abrading floss comprises a plastic sheet of having a dental abrasive thereon or therein situated between lengths of the dental floss. The dental abrasive may be of a single grit or different grits of the dental abrasive. For different grits of the dental abrasive, it is preferred, but not necessary, that they gradually change in grit size.

Priority: US20060837482P Applic. Date: 2006-08-14

Inventor: ALLEN JEFFREY T [US]

Title: Phosphoinositide 3-kinase inhibitor compounds and methods of use

Applicant/Assignee: PLRAMED LIMITED GENENTECH, INC PIRAMED LIMITED

Application No.: 11/789427   Filing Date: 24/Apr/2007

Abstract:

Compounds of Formulas Ia and Ib, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20060795047P Applic. Date: 2006-04-26

Inventor: FOLKES ADRIAN [GB]; SHUTTLEWORTH STEPHEN [GB]; OXENFORD SALLY [GB]; HANCOX TIM [GB]; BAYLISS TRACY [GB]; CASTANEDO GEORGETTE [US]; GOLDSMITH RICHARD [US]; GUNZNER JANET [US]; HEFFRON TIM [US]; MALESKY KIMBERLY [US]; MATHIEU SIMON [US]; OLIVERO ALAN [US]; SUTHERLIN DANIEL P [US]; TSUI VICKIE [US]; WANG SHUMEI [US]; WIESMANN CHRISTIAN [US]; ZHU BING-YAN [US]; DOTSON JENNAFER [US]

Title: Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof

Applicant/Assignee: RENOVIS, INC

Application No.: 11/773106   Filing Date: 03/Jul/2007

Abstract:

Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US2006-384045 Applic. Date: 2006-03-17; US20050664903P Applic. Date: 2005-03-24; US20050709186P Applic. Date: 2005-08-18; US20050710077P Applic. Date: 2005-08-22; US20050712778P Applic. Date: 2005-08-31; US20050721390P Applic. Date: 2005-09-28; US20050753194P Applic. Date: 2005-12-22

Inventor: KELLY MICHAEL G [US]; KINCAID JOHN [US]

Title: Dental Polymerizable Composition

Applicant/Assignee: KURARAY MEDICAL INC

Application No.: 11/659811   Filing Date: 11/Aug/2005

Abstract:

A dental polymerizable composition comprising (a) a fluorine compound comprising a chain polymer having a main chain comprising a monomer unit having a hydrophilic group, and terminal groups comprising a fluoroalkyl group at each of both ends of the main chain

(b) a polymerizable monomer

and (c) a polymerization initiator. The dental polymerizable composition can be suitably used, for example, for dental composite resins, such as dental composite filler materials, crowning materials, and bonding materials

dental adhesive agents, such as teeth-straightening adhesive agents, cavity-coating adhesive agents, and tooth fissure sealing materials

denture base materials, denture base mucosal adjusting materials, fissure sealants, coating agents applied to tooth surface or dental prosthetic, surface glazes, and the like, and especially for various coating applications, for example, a fissure sealant, a coating agent to tooth surface or dental prosthetic, surface stains or a surface glaze, a hypersensitive inhibitor, a dental manicure, or the like.

Priority: JP20040234622 Applic. Date: 2004-08-11; WO2005JP14744 Applic. Date: 2005-08-11

Inventor: SAWADA HIDEO [JP]; TAGAMI JUNJI [JP]; NIKAIDO TORU [JP]; MATIN KHAIRUL [JP]; KADOMA YOSHINORI [JP]; MASUHARA EIICHI [JP]; OKADA KOICHI [JP]; YAMAUCHI JUNICHI [JP]

Title: Light therapeutic device

Applicant/Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Application No.: 11/905943   Filing Date: 05/Oct/2007

Abstract:

A light therapeutic device for an affected part is provided. The light therapeutic device includes an optical element providing light with at least one specific wavelength for treatment of the affected part. When the optical element contacts the affected part, the optical element has a shape corresponding to the shape of the affected part.

Priority: TW20040141350 Applic. Date: 2004-12-30; US2005-074724 Applic. Date: 2005-03-09

Inventor: HUANG SHENG B [TW]; CHEN CHIU L [TW]; YIN SUN B [TW]; YU YU C [TW]

Title: Nozzle For Filling A Container With At Least Two Viscous Materials

Applicant/Assignee:

Application No.: 11/791314   Filing Date: 22/Nov/2005

Abstract:

Nozzle ( 1 ) for filling a container with at least a first and a second viscous or paste-like material, of the type including an outer cylindrical body ( 6 ) having a delivery mouth ( 7 ). The nozzle has at least two cylindrical chambers ( 8, 9 ), placed inside said outer cylindrical body and fluidly separated, for the respective passage of the first and of the second viscous material, each of said at least two chambers having an outflow section ( 10, 11 ) of the relative viscous material substantially positioned in correspondence to said delivery mouth.

Priority: IT2004MI02284 Applic. Date: 2004-11-25; WO2005IB03502 Applic. Date: 2005-11-22

Inventor: TOGNI GIANCARLO [IT]

Title: Methods for Reverse-Circulation Cementing in Subterranean Formations

Applicant/Assignee: HALLIBURTON ENERGY SERVICES HALLIBURTON ENERGY SERVICES INC

Application No.: 11/862292   Filing Date: 27/Sep/2007

Abstract:

Methods and systems for reverse-circulation cementing in subterranean formations are provided. An example of a method is a method of cementing casing in a subterranean well bore, comprising inserting a casing into the well bore, the casing comprising a casing shoe

equipping the casing with a well head, and a casing inner diameter pressure indicator

flowing an equilibrium fluid into the well bore

flowing a cement composition into the well bore after the equilibrium fluid

determining from the well-bore pressure indicator when the well bore pressure has reached a desired value

discontinuing the flow of cement composition into the well bore upon determining that the well bore pressure has reached a desired value

and permitting the cement composition to set in the subterranean formation. Examples of systems include systems for cementing casing in a well bore.

Priority: US2004-973322 Applic. Date: 2004-10-26

Inventor: BADALAMENTI ANTHONY M [US]; BLANCHARD KARL W [US]; CROWDER MICHAEL G [US]; FAUL RONALD R [US]; GRIFFITH JAMES E [US]; ROGERS HENRY E [US]; TURTON SIMON [US]

Title: Closure device for drinking vessel

Applicant/Assignee:

Application No.: 11/496479   Filing Date: 01/Aug/2006

Abstract:

A closure device for use at the opening of a drinking vessel, comprises a body for connection to the drinking vessel at the opening, and a valve comprising a valve member supported by the body for movement relative to the body, between an inner open position allowing flow of liquid from inside to outside of the drinking vessel through the opening and an outer closed position sealing the opening. A spring resiliently biases the valve member towards the closed position. The valve member has an internal passage through which liquid from inside the drinking vessel may flow out of the drinking vessel when the valve member is in the open position.

Priority:

Inventor: SHEK TAT KIT [HK]

Title: Drink Cup and Lid

Applicant/Assignee: BERRY PLASTICS CORPORATION

Application No.: 11/876831   Filing Date: 23/Oct/2007

Abstract:

A liquid container includes a brim forming an opening into a liquid reservoir chamber formed in the cup. A lid is coupled to the brim to form more than one seal with the container. The lid includes lid-removal blocker walls arranged to engage undercuts formed in the cup to retain the lid in a mounted position on the cup closing the opening into the liquid reservoir chamber.

Priority: US2005-210085 Applic. Date: 2005-08-23; US2004-824753 Applic. Date: 2004-04-15

Inventor: JOCHEM DAVID J [US]; MARAVICH MILAN C [US]; MANN JEFFREY A [US]

Title: TRASH BAG HAVING FLEXIBLE SOLID EDGE

Applicant/Assignee:

Application No.: 11/735240   Filing Date: 13/Apr/2007

Abstract:

A bag for collecting refuse or yard waste is disclosed. The bag may include one or more solid edges to keep the bag open when in a horizontal or when in an upright position. The solid edge may flip out to act as a guide for refuse into the bag. The bag may also include a loop handle that may be held by the user to facilitate the bag staying open in the horizontal position, or a hook or clip that facilitates the bag staying open in the upright position.

Priority: US20060791415P Applic. Date: 2006-04-13

Inventor: FARAONE ROSEMARIE [US]

Title: METHOD AND PROCEDURE TO DETECT ORAL TISSUES WITH HIGH-RISK MOLECULAR PROFILES

Applicant/Assignee:

Application No.: 11/464536   Filing Date: 15/Aug/2006

Abstract:

A diagnostic method for detecting high risk oral tissue which due to chromosome allelic loss and may have developed or will potentially develop into carcinoma in situ and carcinoma by using a staining agent. A set of questionnaire that identifies high-risk individual and high-risk lesions and helps to reduce false positive for the diagnosis of oral tissue with high-risk molecular profile. A recording sheet with oral cavity diagram that helps to record the examination results more accurately and reduce the examination errors. This improved method has a broad application that can be used to screen the oral tissues with high risk molecular profile from hyperplasia, dysplasia, erythroplasia, leukoplasia, leukoerythroplasia, erythroleukoplasia, verrucous lesion, ulcerative lesion, carcinoma in situ, and carcinoma.

Priority:

Inventor: YE XIN [US]

Title: Therapeutic Dental Composition

Applicant/Assignee: BRITESMILE PROFESSIONAL, LLC

Application No.: 11/927129   Filing Date: 29/Oct/2007

Abstract:

A solid or semi-solid oral therapeutic dental composition comprising a therapeutic agent dispersed in a water-insoluble or water-resistant carrier. The dental composition may be in the form of a crayon or dispensed from a delivery device such as a pen or the like.

Priority: US2004-846207 Applic. Date: 2004-05-14; US20030471427P Applic. Date: 2003-05-16

Inventor: MONTGOMERY R E [US]

Title: Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof

Applicant/Assignee: FOAMIX LTD

Application No.: 11/825406   Filing Date: 05/Jul/2007

Abstract:

The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester

a stabilizer selected from the group consisting of at least one surface-active agent

at least one polymeric agent and mixtures thereof

a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

Priority: IL20020152486 Applic. Date: 2002-10-25; US2005-532618 Applic. Date: 2005-12-22; WO2003IB05527 Applic. Date: 2003-10-24; US2005-078902 Applic. Date: 2005-03-11; US2007-717897 Applic. Date: 2007-03-13; US2007-653205 Applic. Date: 2007-01-12; US2004-835505 Applic. Date: 2004-04-28; US2004-911367 Applic. Date: 2004-08-04; US20060818634P Applic. Date: 2006-07-05; US20020429546P Applic. Date: 2002-11-29; US20030492385P Applic. Date: 2003-08-04; US20030530015P Applic. Date: 2003-12-16

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; BERMAN TAL [IL]; ZIV ENBAL [IL]; SCHUZ DAVID [IL]

Title: Biological Surfaces

Applicant/Assignee: RHO-BEST COATING HARTSTOFFBESCHICHTUNGS GMBH

Application No.: 11/792613   Filing Date: 07/Dec/2005

Abstract:

A base body contains a substrate that is at least partially coated with a carbon-containing layer. The carbon-containing layer is at least partially functionalized with a molecule that is bound directly or via at least one linker or functional group to the carbon-containing layer. The base body, which has a functionalized carbon-containing surface, is capable of influencing biological processes during a corresponding functionalization.

Priority: AT20040002063 Applic. Date: 2004-12-07; WO2005AT00495 Applic. Date: 2005-12-07

Inventor: STEINMULLER-NETHL DORIS [AT]; STEINMULLER DETLEF [AT]; KLOSS FRANK R [AT]; GASSNER ROBERT [AT]; BONN GUNTHER [AT]; HUCK CHRISTIAN W [AT]; NAJAM-UL-HAQ MUHAMMED [AT]; RAINER MATTHIAS [AT]; STECHER GUNTHER [AT]

Title: Nano Glass Powder and Use Thereof, in Particular Multicomponent Glass Powder with a Mean Particle Size of Less Than 1 [mu]m

Applicant/Assignee: SCHOTT AG

Application No.: 11/597959   Filing Date: 25/May/2005

Abstract:

A glass powder or a glass-ceramic powder is provided that includes multicomponent glasses with at least three elements, where the glass powder or a glass-ceramic powder has a mean particle size of less than 1 mum. In some embodiments, the mean particle size is less than 0.1 mum, while in other embodiments the mean particle size is less than 10 nm.

Priority: DE200410026433 Applic. Date: 2004-05-29; WO2005EP05633 Applic. Date: 2005-05-25

Inventor: ZIMMER JOSE [DE]; DAIMER JOHANN [DE]; RINDT MATTHIAS [DE]; KESSLER SUSANNE [DE]; BESINGER JOERN [DE]; SENESCHAL-MERZ KARINE [DE]

Title: DOUBLE ENDED LIGHTED DENTAL CLEANER

Applicant/Assignee:

Application No.: 11/465593   Filing Date: 18/Aug/2006

Abstract:

A lighted dental cleaning and inspection device. The device includes a handle having an end including a dental tool and an illumination source positioned and operable to direct light toward a tip portion of the dental tool

and an electrical circuit located substantially within the handle and being operable to selectively enable illumination of the illumination source to illuminate the tip portion of the dental tool and an area of interest during use of the dental tool at the site of interest.

Priority:

Inventor: JANSHESKI JOHN M [US]; SHANKLE LEX [US]

Title: Polynucleotide encoding a TRIM-cyp polypeptide, compositions thereof, and methods of using same

Applicant/Assignee:

Application No.: 11/650384   Filing Date: 05/Jan/2007

Abstract:

The invention provides an isolated nucleic acid encoding a TRIM-cyclophilin A fusion sequence encoding a TRIMcyp fusion protein which is active as an anti-viral agent, and in particular an anti-HIV-1 agent. The invention provides for a nucleic acid encoding a polypeptide having both TRIM activity and cyclophilin activity. The invention provides for an isolated polynucleotide encoding a TRIM-cyclophilin fusion protein, or variants thereof retaining the TRIM and cyclophilin activities. The invention provides for compositions thereof, antibodies that specifically bind thereto, and vectors and host cells comprising the nucleic acid or polypeptide. In addition, the invention provides for methods for treating or preventing viral infection, or reducing viral load in a subject comprising administering the nucleic acid, polypeptide, vector, or composition to the subject in an amount effective to treat or prevent the viral infection. In some embodiments, the viral infection is HIV-1 infection, hepatitis C infection, pox virus infection, vaccinia virus infection, or HTLV infection.

Priority: WO2005US23803 Applic. Date: 2005-07-06; US20040585925P Applic. Date: 2004-07-06

Inventor: LUBAN JEREMY [US]; SAYAH DAVID [US]

Title: Piperazinyl-Pyridine Analogues

Applicant/Assignee:

Application No.: 11/793129   Filing Date: 13/Dec/2005

Abstract:

Piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to. modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20040635822P Applic. Date: 2004-12-13; WO2005US45184 Applic. Date: 2005-12-13

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; BLUM CHARLES A [US]; CHENARD BERTRAND L [US]; ZHENG XIAOZHANG [US]

Title: FUSED HETEROCYCLIC COMPOUNDS USEFUL AS KINASE MODULATORS

Applicant/Assignee: BRISTOL-MYERS SQUIBB COMPANY

Application No.: 11/689132   Filing Date: 21/Mar/2007

Abstract:

Compounds having the formula (I), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, are useful as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, Z is N or CR3, and R1, R2, R3, X and Y are as defined herein.

Priority: US2006-524996 Applic. Date: 2006-09-21; US20050719519P Applic. Date: 2005-09-22

Inventor: VACCARO WAYNE [US]; CHEN ZHONG [US]; DODD DHARMPAL S [US]; HUYNH TRAM N [US]; LIN JAMES [US]; LIU CHUNJIAN [US]; MUSSARI CHRISTOPHER P [US]; TOKARSKI JOHN S [US]; TORTOLANI DAVID R [US]; WROBLESKI STEPHEN T [US]; LIN SHUQUN [US]

Title: Delivery of H2 Antagonists

Applicant/Assignee:

Application No.: 11/793884   Filing Date: 20/Dec/2005

Abstract:

The present invention provides methods for treating or preventing periodontal disease in a mammal subject. The inventive methods comprise topically administering to the subject an effective amount of a H2 antagonist encapsulated in liposomes. Preferably, the H2 antagonist, for example, Cimetidine, is encapsulated into paucilamellar liposomes, such as Novasome(R) microvesicles. The inventive methods may be used to treat and/or prevent gingivitis, periodontitis, aphthous ulcers, or herpetic stomatitis. Alternatively, the inventive methods may be used to treat and/or prevent a systemic disease associated with periodontal disease, such as cardiovascular diseases, pregnancy complications, and diabetes.

Priority: US20040639892P Applic. Date: 2004-12-29; WO2005US46280 Applic. Date: 2005-12-20

Inventor: VAN DYKE THOMAS E [US]; HOLICK MICHAEL [US]; KANTARCI ALPDOGAN [US]; HASTURK HATICE [US]

Title: Chemical Compounds

Applicant/Assignee: PHYTOPHARM PLC

Application No.: 11/773952   Filing Date: 05/Jul/2007

Abstract:

Compounds of general formula I: wherein: R1 and R2 are, independently of each other, selected from hydrogen, optionally substituted C1-10alkyl, optionally substituted -CO-(C1-10alkyl), optionally substituted C3-10cycloalkyl, optionally substituted -CO-(C3-10cycloalkyl), optionally substituted C2-10alkenyl, optionally substituted -CO-(C2-10alkenyl), optionally substituted aryl, and optionally substituted -CO-aryl, or R1 and R2 together represent an optionally substituted saturated or unsaturated C1-10alkylidene group, or an optionally substituted saturated or unsaturated C3-10cycloalkylidene group, or R1 and R2 together with the carbon atom to which they are attached represent an optionally substituted saturated or unsaturated organic ring containing 3, 4, 5, 6, 7 or 8 ring carbon atoms and optionally 1, 2 or 3 ring heteroatoms selected from O, N and S

R3, which may be the same as, or different from, either of R1 and R2, is selected from optionally substituted C1-10alkyl, optionally substituted C3-10cycloalkyl, optionally substituted C2-10alkenyl, and optionally substituted aryl

R4, R5 and R6 are, independently of each other, selected from hydrogen, optionally substituted C1-10alkyl, OH, optionally substituted C1-10 alkoxy, halo, optionally substituted aryloxy, optionally substituted (C1-10alkyl)-S(O)n- where n=0, 1 or 2, optionally substituted aryl-S(O)n- where n=0, 1 or 2, or R4 is hydrogen and R5 and R6 together represent an optionally substituted saturated or unsaturated organic chain containing 1, 2, 3, 4, 5, 6 or 7 chain carbon atoms and optionally 1, 2 or 3 chain heteroatoms selected from O, N and S, provided that the chain is at least 3 atoms long

with the proviso that, when R1-R2=hydrogen, then any optionally substituted C1-10alkyl or optionally substituted C2-10alkenyl for R3 must have a branch point at one or more of the alpha and beta positions counted from the carbonyl group (or tautomeric form thereof) to which R3 is attached

or a physiologically acceptable salt, complex or prodrug thereof

are disclosed per se and for use in the treatment or prophylaxis of hypersensitivity, smooth muscle disorders, spasmodic conditions, allergic conditions, inflammatory conditions and/or pain.

Priority: GB20060013518 Applic. Date: 2006-07-06

Inventor: REES DARYL D [GB]; GUNNING PHILLIP J [GB]; ORSI ANTONIA [GB]; HOWSON PATRICK A [GB]; BARRACLOUGH PAUL [GB]; CALLIZOT NOELLE [GB]

Title: Dental Compositions Containing Carbosilane Polymers

Applicant/Assignee:

Application No.: 11/571949   Filing Date: 13/Jul/2005

Abstract:

Carbosilane-containing polymers (including oligomers) having the following structural features: greater than one repeat unit

at least 4 Si-arylene bonds

at least 1 (meth)acrylate moiety, Si-H moiety, or both

no Si-O bonds

preferably at least 4 silicon atoms

wherein 2 silicon atoms are separated by one arylene group in each repeat unit.

Priority: US20040587978P Applic. Date: 2004-07-14; WO2005US24821 Applic. Date: 2005-07-13

Inventor: LEWANDOWSKI KEVIN M [US]; ABUELYAMAN AHMED S [US]; JONES TODD D [US]; GADDAM BABU N [US]; MITRA SUMITA B [US]; KARIM NAIMUL [US]; ECKERT ANDRIAN S [DE]; BISSINGER PETER [DE]

Title: Production of Acrylate-Based Solid

Applicant/Assignee:

Application No.: 11/664152   Filing Date: 03/Nov/2005

Abstract:

According to the invention, there is a method for producing an acrylate-based solid, comprising the steps of: (i) dispersing less than 20% w/v of an alkyl or aryl acrylate polymer/copolymer in a solvent comprising at least one acrylic monomer

(ii) dispersing in the fluid mixture formed by step (i) a further quantity of an alkyl or aryl acrylate polymer/copolymer

and (iii) curing the resulting material to form a solid, Wherein the alkyl or aryl acrylate polymer/copolymer of step (i) contains less than 0.1% w/w of a free radical.

Priority: GB20040024353 Applic. Date: 2004-11-03; GB20040027576 Applic. Date: 2004-12-16; WO2005GB04262 Applic. Date: 2005-11-03

Inventor: AHIR VALLABHBHAI B [GB]

Title: COVERAGE ROBOTS AND ASSOCIATED CLEANING BINS

Applicant/Assignee: IROBOT CORPORATION

Application No.: 11/751267   Filing Date: 21/May/2007

Abstract:

An autonomous coverage robot includes a chassis, a drive system configured to maneuver the robot, and a cleaning assembly. The cleaning assembly includes a cleaning assembly housing and at least one driven sweeper brush. The robot includes a controller and a removable sweeper bin configured to receive debris agitated by the driven sweeper brush. The sweeper bin includes an emitter disposed on an interior surface of the bin and a receiver disposed remotely from the emitter on the interior surface of the bin and configured to receive an emitter signal. The emitter and the receiver are disposed such that a threshold level of accumulation of debris in the sweeper bin blocks the receiver from receiving emitter emissions. The robot includes a bin controller disposed in the sweeper bin and monitoring a detector signal and initiating a bin full routine upon determining a bin debris accumulation level requiring service.

Priority: US20060747791P Applic. Date: 2006-05-19; US20060803504P Applic. Date: 2006-05-30; US20060807442P Applic. Date: 2006-07-14

Inventor: SCHNITTMAN MARK [US]; OZICK DANIEL N [US]; LANDRY GREGG W [US]

Title: Tote bag for organizing, securing and safely transporting laundry supplies

Applicant/Assignee:

Application No.: 11/508483   Filing Date: 23/Aug/2006

Abstract:

A tote bag for organizing, securing and safely transporting laundry supplies which comprises a box-shaped housing having a bottom wall, a pair of side walls, a rear wall and a lower front wall. A flap can be folded over to cover a top and an upper front portion area of the box-shaped housing. A plurality of box-shaped laundry supply containers are sized and proportioned so that they can fit within the box-shaped housing in a side-by-side relationship to utilize almost the entire confines of the box-shaped housing without any appreciable left over wasted space therein. A mechanism is for securing all of the box-shaped laundry supply containers snugly within the box-shaped housing. When the flap is opened and the securing mechanism is removed therefrom all of the box-shaped laundry supply containers can be easily taken out of the box-shaped housing.

Priority:

Inventor: CAPORRINO ROMINA V [US]

Title: WINE GLASS

Applicant/Assignee: BY THE GLASS, LLC

Application No.: 11/932179   Filing Date: 31/Oct/2007

Abstract:

A wine glass constructed from molded plastic includes an upper body defining an upwardly narrowed flume for concentrating the wine bouquet, in combination with a contoured lower base defining an annular moat surrounding a central punt for enhanced visual inspection of the wine. In addition, the upper body further includes a notched indent at an outboard side thereof forming a shelf for facilitated fingertip grasping and manipulation of the assembled glass. In one form, the upper body and lower base of the wine glass are provided as separate modules adapted for assembly to form the wine glass, and disassembly for respective compact stacking. In another form, the wine glass has a one-piece construction adapted for compact stacking by nested reception of the upwardly narrowed flume partially into the underside of the lower base of an overlying glass in the stack.

Priority: US2004-979847 Applic. Date: 2004-11-01; US2006-309159 Applic. Date: 2006-07-03; US2007-668046 Applic. Date: 2007-01-29

Inventor: WILLAT BOYD I [US]; PERRULLI JOSEPH T [US]; WILLAT AMBER R [US]; VELICK PAUL H [US]; DELGADO GARY D [US]

Title: Use of a combination of components with an inhibitory synergistic effect on calcium channels to prevent or treat wrinkles and fine lines

Applicant/Assignee: L'OREAL S.A

Application No.: 11/434266   Filing Date: 16/May/2006

Abstract:

Disclosed herein is a composition for topical application to skin, comprising, in a physiologically acceptable medium (i) at least one peptide comprising at least one amino acid sequence derived from the amino acid sequence of the protein SNAP 25, and (ii) at least one calcium-channel inhibitor. Further disclosed is the use of this combination in a composition suitable for topical application to the skin, as an agent for preventing or treating wrinkles and fine lines, such as expression wrinkles, as well as a cosmetic treatment process comprising applying to the skin the composition.

Priority: FR20020014183 Applic. Date: 2002-11-13; US2003-705857 Applic. Date: 2003-11-13; US20020427575P Applic. Date: 2002-11-20

Inventor: RENAULT BEATRICE [FR]

Title: Composition Comprising Beta-Defensin 2

Applicant/Assignee:

Application No.: 11/864386   Filing Date: 28/Sep/2007

Abstract:

The invention relates to compositions comprising at least one peptide with a structure or structural pattern of beta-defensin 2 and/or its derivatives, especially human beta-defensin 2. The compositions are selected in particular from cosmetic and/or pharmaceutical compositions, cleaning and/or washing agents, water-treatment agents and cooling lubricants. The invention also relates to the use of peptides with a structure or structural pattern of beta-defensin 2 and/or its derivatives, especially human beta-defensin 2, as an antimicrobial active ingredient in the aforementioned agents.

Priority: DE200510014687 Applic. Date: 2005-03-29; WO2006EP02760 Applic. Date: 2006-03-25

Inventor: BOCKMUEHL DIRK [DE]; HOEHNE HEIDE-MARIE [DE]

Title: ORAL CARE PRODUCTS COMPRISING BUFFER SYSTEMS FOR IMPROVED MINERALIZATION/REMINERALIZATION BENEFITS

Applicant/Assignee:

Application No.: 11/670737   Filing Date: 02/Feb/2007

Abstract:

Oral products for the improved mineralization/remineralization of teeth are provided. In an embodiment, the present disclosure provides an oral product comprising a calcium salt, a phosphate salt, a sodium salt and a potassium salt. For example, the molar ratio of the sodium salt to the potassium salt ranges from about 3 to about 4.

Priority: US20060765289P Applic. Date: 2006-02-03

Inventor: HAAS MICHAEL S [US]

Title: Cheese Products

Applicant/Assignee: DANISCO A/S

Application No.: 10/588320   Filing Date: 03/Feb/2005

Abstract:

The present invention relates to a composition and a method of preparing cheese products with a suitable moisture level. The cheese products that have been formed using the composition are characterised with an improve at least one of aroma, flavour, mildness, consistency, texture, syneresis, body, mouth feel, firmness, viscosity, gel fracture, wheying off, structure and/or organoleptic properties, nutrition and/or health benefits. In particular, the present invention provides a composition comprising a starter acidification micro-organism and an EPS fermentation culture comprising a viable micro-organism an enzyme produced by said micro-organism and an exopolysaccharide (EPS) produced by the activity of said enzyme.

Priority: GB20040002474 Applic. Date: 2004-02-04; GB20040003169 Applic. Date: 2004-02-12; US20040544331P Applic. Date: 2004-02-17; WO2005IB00427 Applic. Date: 2005-02-03

Inventor: SCHLOTHAUER RALF-CHRISTIAN [NZ]; RADEMACHER INEZ [DE]; PETERSEN HANS-UWE [DE]; HINRICHS JORG [DE]; LILLEVANG SOREN KRISTIAN [DK]

Title: NON-CUSTOM DENTAL TREATMENT TRAYS AND MOUTH GUARDS HAVING IMPROVED ANATOMICAL FEATURES

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/836664   Filing Date: 09/Aug/2007

Abstract:

A non-custom, dental tray device includes a moisture-resistant barrier layer having a labial-buccal wall, a lingual wall, and a bottom wall. The dental tray device includes at least one of the following structural features to enhance the fit of the device

(1) the bottom wall includes an abrupt reduction of width at a location corresponding to where the first bicuspid meets the canine

(2) a bottom wall in the posterior region having a width that is equal to or less than the width of the bottom wall in the anterior region, with no lingual wall in the posterior region

or (3) a transition portion between the bottom wall and either the labial-buccal wall or the lingual wall has a larger radius of curvature as compared to a radius of curvature at a transition portion between the bottom wall the other of the labial-buccal wall and the lingual wall.

Priority: US20060932982P Applic. Date: 2006-08-25

Inventor: FISCHER DAN E [US]; ALLRED PETER M [US]; JESSOP NEIL T [US]; MCLEAN BRUCE S [US]

Title: Fountain toothbrush

Applicant/Assignee:

Application No.: 11/821353   Filing Date: 22/Jun/2007

Abstract:

A toothbrush body includes a handle connected to a head and bristles projecting from the top of the head. A channel runs longitudinally through the body between a first opening and a second opening such that the first opening is in communication with the second opening through the channel. The channel and the first and second openings are arranged so that a substantially downward running stream of water directed into one of the first opening and the second opening is redirected through the channel and out of the other of the first opening and the second opening to form a fountain. A direction of a flow of the fountain at the other of the first opening and the second opening has an upward component so that a user, i.e., holder of the toothbrush, can easily reach the fountain for oral rinsing.

Priority: US2006-401702 Applic. Date: 2006-04-11

Inventor: AMRON SCOTT L [US]

Title: Methods, Articles, and Compositions for Identifying Oligonucleotides

Applicant/Assignee:

Application No.: 10/583198   Filing Date: 15/Nov/2004

Abstract:

There are many situations where oligonucleotides that efficiently bind a target DNA or RNA are desired. These oligonucleotides can be used for a variety of purposes, including antisense, diagnostics, and array generation. While researchers have worked for many years to identify algorithms and methods for predicting the oligonucleotides that will bind the target with the highest efficiency, better prediction methods are needed. Disclosed are methods, articles, machines, and compositions that aid in identifying oligonucleotides and sets of oligonucleotides that will efficiently bind a target nucleic acid molecule. Also disclosed are optimized sets of oligonucleotides that bind HIV-1 genomic RNA or DNA, such as the GAG RNA, and methods of using them.

Priority: US20030519911P Applic. Date: 2003-11-14; WO2004US38092 Applic. Date: 2004-11-15

Inventor: GESTELAND RAYMOND F [US]; ATKINS JOHN F [US]; MATVEEVA OLGA V [US]; SHABALINA SVETLANA A [US]

Title: Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses

Applicant/Assignee:

Application No.: 11/404041   Filing Date: 14/Apr/2006

Abstract:

Novel compositions and methods of treating and preventing a viral infection are provided. A method of blocking a viral infection facilitated by a serine proteolytic (SP) activity is disclosed, which involves administering to a subject suffering or about to suffer from a viral infection a therapeutically effective amount of a substance having serine protease inhibitory activity or serpin activity. Among the substances found to be useful are alpha1-antitrypsin (AAT), peptide derivatives from the carboxy terminal end of AAT and synthetic drugs mimicking the action of such substances. The invention is particularly well suited for checking a viral infection mediated by members of herpesviridae family.

Priority: US2000-518076 Applic. Date: 2000-03-03; US19990123167P Applic. Date: 1999-03-05; US19990153942P Applic. Date: 1999-09-15

Inventor: SHAPIRO LELAND [US]

Title: Dental Composition Containing Unsaturated Halogenated Aryl Alkyl Ether Components

Applicant/Assignee: TDK CORPORATION

Application No.: 11/572067   Filing Date: 14/Jul/2004

Abstract:

The invention relates to a dental composition comprising a) halogenated aryl alkyl ether component (A) comprising at least 1 aryl alkyl ether moiety, at least 1 halogen atom attached to each aryl residue of the aryl alkyl ether moieties, at least 2 unsaturated moieties, b) Si-H functional component (B), c) initiator (C), d) optionally filler (D), and e) optionally component (E) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickness, surfactants, odorous substances, diluting agent(s) and flavourings.

Priority: WO2004EP07747 Applic. Date: 2004-07-14

Inventor: ECKERT ADRIAN S [DE]

Title: Devices and methods for treatment of obesity

Applicant/Assignee:

Application No.: 11/881144   Filing Date: 24/Jul/2007

Abstract:

Devices, methods for treatment of obesity, as well as instruments and tools used in placing, adjusting and maintaining devices for treatment of obesity. Various embodiments of devices that are implanted extra-gastrically are provided. Various embodiments of devices that are implanted intra-gastrically are provided. Methods include laparoscopic, percutaneous and/or trans-oral methods. Alternatively, devices describe can generally also be implanted by open surgical procedures.

Priority: US2007-716986 Applic. Date: 2007-03-10; US2007-716985 Applic. Date: 2007-03-10; US2006-407701 Applic. Date: 2006-04-19; US20060833284P Applic. Date: 2006-07-24; US20060877595P Applic. Date: 2006-12-28

Inventor: MAKOWER JOSHUA [US]; KIM STEVEN [US]; SHIU BRIAN K [US]; UEMURA SHUJI [US]; ACOSTA PABLO G [US]

Title: METHOD AND DEVICES FOR STIMULATION OF AN ORGAN WITH THE USE OF A TRANSECTIONALLY PLACED GUIDE WIRE

Applicant/Assignee: INTRAPACE, INC

Application No.: 11/830419   Filing Date: 30/Jul/2007

Abstract:

Devices, systems and methods are provided for electrical stimulation of a body organ, particularly within the gastrointestinal tract. In preferred embodiments, the stomach is the organ within the gastrointestinal tract which is targeted for such stimulation. A guide wire or other delivery device is positioned within the body so as to transect the stomach wall. Devices and systems are then advanced over the guide wire for attachment to the stomach wall. The guide wire may be placed by endoscopic, open, laparoscopic or a modified percutaneous approach. In a modified percutaneous approach, the stomach is accessed without the use of general anesthesia by advancing a needle through the abdomen, transecting the stomach wall with the needle and advancing the guide wire through the needle.

In some embodiments, particularly for use in obese patients, the modified percutaneous approach includes advancing a trocar through the tissue of the patient toward the outer surface of the organ and advancing the needle through the trocar prior to transecting the wall with the needle.

Priority: US20060821370P Applic. Date: 2006-08-03

Inventor: SPARKS KURT D [US]; BRYNELSEN CHARLES R [US]; IMRAN MIR A [US]

Title: Cosmetic mask and method of using

Applicant/Assignee:

Application No.: 11/894901   Filing Date: 22/Aug/2007

Abstract:

A multi-layer cosmetic mask designed to enhance the absorption of skin care compositions is disclosed. The mask comprises a thermally reflective layer, composed of foil or similar material, and a thermally insulating layer, composed of fleece or similar material. A method of using the cosmetic mask is also disclosed, comprising the steps of applying a moisturizing composition to the skin, applying the thermally reflective foil layer over the moisturizer, and then applying the thermally insulating mask layer over the foil layer. The combination of layers increases the temperature under the mask, and thereby increases the absorption of the moisturizing composition into the skin of a user.

Priority: ZA20060007007 Applic. Date: 2006-08-22

Inventor: WYK JOHAN D V [ZA]

Title: Oral Care Implement

Applicant/Assignee:

Application No.: 11/932010   Filing Date: 31/Oct/2007

Abstract:

An oral care implement with a handle includes a head with a tissue cleanser. The tissue cleanser may be a pad composed of an elastomeric material. The pad is disposed on the head on a surface opposite the tooth cleaning elements. The tissue cleanser may include a plurality of nubs extending for cleaning between the papillae of the tongue. The tissue cleanser may include a plurality of conically shaped nubs. A tissue cleanser can be used to reduce oral malodor problems and remove oral epithelial cells.

Priority: US2006-566479 Applic. Date: 2006-12-04; US2004-869922 Applic. Date: 2004-06-18; US2003-601106 Applic. Date: 2003-06-20; US20020414117P Applic. Date: 2002-09-27; US20020418776P Applic. Date: 2002-10-16; US20020419425P Applic. Date: 2002-10-18; US20020412290P Applic. Date: 2002-09-20

Inventor: HOHLBEIN DOUGLAS J [US]

Title: Anti-Snoring Device

Applicant/Assignee:

Application No.: 11/470319   Filing Date: 06/Sep/2006

Abstract:

An inter-lip device for regulating mouth airflow to prevent snoring while sleeping. A canoe shaped horizontal pocket is formed by hinge-ably attaching two resilient panels together by three common edges, sized to fit between the lips without protruding into the mouth. An adhesive covering is applied to both outer faces of the pocket and a slit is cut in the middle of the front edge hinge. The pocket opens to the rear into the mouth. The lips are sealed to the adhesive about the pocket opening, holding the mouth closed while directing mouth breathing through the device and out the front slit opening. With the jaw consciously flexed, resting mouth airflow is comfortably allowed, however, a relaxed sleeper's jaw or a forced inhalation will collapse the slit opening, reducing or stopping airflow, causing the user to breath through their nose, thereby preventing the necessary mouth airflow needed to support snoring.

Priority:

Inventor: SILKER NEIL BRADLEY [US]

Title: Burr hog cleaning device

Applicant/Assignee:

Application No.: 11/897750   Filing Date: 01/Sep/2007

Abstract:

An automated cleaning device for dental drill bits, also called dental burrs. The cleaning device includes an enclosed cleaning compartment that houses two rotating, circular brushes. The dental burr is guided through a small opening in the cleaning compartment and forced in between the two rotating brushes. The dental burr is rotated while between the brushes and moved in and out of the brushes during the cleaning process. A switch attached to the opening in the cleaning compartment allows the brushes to start rotating when a dental burr is inserted into the compartment, and stop when the burr is removed. The device includes an electric motor that can be powered by batteries or by plugging into a traditional electrical outlet.

Priority: US20060841375P Applic. Date: 2006-09-01

Inventor: HANCOCK J DENNIS [US]; KIMMEL SHAWN [US]

Title: Aerosol delivery system for dispensing dental compositions

Applicant/Assignee:

Application No.: 11/801831   Filing Date: 11/May/2007

Abstract:

An aerosol delivery system for dispensing a multi-component dental composition is provided. The system is particularly suitable for dispensing dental impression material containing mixed components A and B. The system includes a dispensing device having an inner container with pressurized aerosol chambers. The first chamber is used for storing and dispensing component A, and the second chamber is used for storing and dispensing component B. The dispensing device includes a piston assembly having a first piston member that slides within the first chamber and a second piston member that slides within the second chamber. The pistons force the components into a common manifold, and the combined material is fed into a dispensing tip containing a static mixer, wherein the material is mixed and then dispensed.

Priority: US20060799481P Applic. Date: 2006-05-11

Inventor: PIERSON PAUL R [US]; HARE ROBERT V [US]

Title: DENTAL COMPOSITIONS HAVING ANTI-STOKES UP CONVERTERS AND METHODS OF USE

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/931290   Filing Date: 31/Oct/2007

Abstract:

A dental composition can include at least one polymerizable resin and at least one anti-stokes up converter. Alternatively, a two-part composition can include at least one dental composition configured for placement onto a person's tooth, and at least one anti-stokes up converter to be combined with the at least one dental composition. The dental composition can be formulated to blend with a person's tooth, and also be capable of changing color to be distinguishable from the tooth when exposed to long wavelength light. The dental composition can be used in a method for performing a dental procedure by applying the dental composition to a tooth, and exposing the dental composition to long wavelength light. Accordingly, the dental composition can aid a dental professional in distinguishing between the location of the dental composition and the tooth.

Priority: US2005-066013 Applic. Date: 2005-02-25

Inventor: LOVERIDGE DAN [US]

Title: HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS

Applicant/Assignee:

Application No.: 11/851106   Filing Date: 06/Sep/2007

Abstract:

The present invention relates to the formation of hydrogels based on guanosine hydrazide derivatives in the presence of cations. The hydrogels can be used as a carrier/delivery system for biologically active substances such as flavors, fragrances, insect attractants or repellents, bactericides, fungicides, pharmaceuticals or agrochemicals.

Priority: WO2005IB00815 Applic. Date: 2005-03-24; WO2006IB50876 Applic. Date: 2006-03-22

Inventor: LEHN JEAN-MARIE [FR]; SREENIVASACHARY NAMPALLY [FR]; HERRMANN ANDREAS [CH]

Title: ORAL HYGIENE PRODUCTS CONTAINING ASCORBIC ACID AND METHOD OF USING THE SAME

Applicant/Assignee: DENTECH, INC

Application No.: 11/874637   Filing Date: 18/Oct/2007

Abstract:

The present invention is directed to dental compositions, including dentifrices, containing ascorbic acid for removing and inhibiting dental biofilms which form plaque and tartar, and also for treating and preventing gingivitis and periodontitis. The ascorbic acid composition can contain may additional ingredients, including an enamel-strengthening component, and be used in many different forms, including breath spray, chewing gum, dental floss, dental powder, gargle, lozenge, mouth spray, mouth wash, tooth gel, tooth liquid, tooth paste and tooth strips. Also described in a method of using a dental composition containing ascorbic acid in order to treat plaque and tartar as well as gum disorders.

Priority: US2006-365167 Applic. Date: 2006-03-01

Inventor: LEONHARDT CHARLES [US]; BUSBY JOHN C [US]

Title: Erbb3 Based Methods and Compositions for Treating Neoplasms

Applicant/Assignee: ZENSUN (SHANGHAI) SCIENCE AND TECHNOLOGY LIMITED

Application No.: 10/516759   Filing Date: 26/Mar/2003

Abstract:

The present invention relates to compositions and methods for treating neoplasms in mammals, particularly humans. More particularly, the present invention provides for methods for preventing, treating or delaying neoplasm in a mammal using an ErbB-3 protein, a nucleic acid encoding an ErbB-3 protein or a functional fragment thereof. The present invention also provides for isolated nucleic acids encoding an extracellular domain of the ErbB-3 protein, or a functional fragment thereof, substantially purified extracellular domain of the ErbB-3 protein, or a functional fragment thereof and antibodies that bind to an epitope in an extracellular domain of the ErbB-3 protein, or a functional fragment thereof. The present invention further provides for pharmaceutical compositions and/or vaccines comprising the extracellular domain of the ErbB-3 protein, or a functional fragment thereof, or nucleic acids encoding and antibodies binding to such extracellular domain or functional fragments thereof.

Priority: CN20021016259 Applic. Date: 2002-03-26; WO2003CN00217 Applic. Date: 2003-03-26

Inventor: ZHOU MINGDONG [CN]

Title: Dental whitening strips

Applicant/Assignee: CREATIVE SPECIALITY PRODUCTS, LLC

Application No.: 11/891730   Filing Date: 13/Aug/2007

Abstract:

A dental whitening strip which includes a carrier support having a whitening composition adhered to said carrier where the whitening composition comprises (a) dextrin

(b) a peroxide

(c) a non-toxic water soluble inorganic salt

(d) a acceptable hydroxy compound which is a plasticizer.

Priority: US20060839027P Applic. Date: 2006-08-21

Inventor: DRONZEK PETER J JR [US]; GROSS LEONARD B [US]; FERNANDEZ LESLIE U [US]

Title: Oral Products

Applicant/Assignee: BIOTEC FILMS, LLC

Application No.: 11/596630   Filing Date: 17/May/2005

Abstract:

An apparatus and method for forming a polymer film and/or oral dosage form having an active, content such as a vitamin, that is a considerable or relatively high proportion of the total dry weight percent without being unpleasant to taste, leaving a bitter after taste, having poor mouth feel and/or being slow to dissolve.

Priority: US20040571949P Applic. Date: 2004-05-17; WO2005US17287 Applic. Date: 2005-05-17

Inventor: KNOOP HENRY [US]; SCHANEVILLE TARA [US]

Title: COMPOSITIONS AND METHODS FOR TREATING MIDDLE-OF-THE NIGHT INSOMNIA

Applicant/Assignee:

Application No.: 11/833507   Filing Date: 03/Aug/2007

Abstract:

The present invention provides compositions and methods for treating middle-of-the-night insomnia without residual sedative effects upon awakening by administering low doses (about 5 mg or less) of zolpidem or a salt thereof.

Priority: US2006-606640 Applic. Date: 2006-11-29; WO2006US20502 Applic. Date: 2006-05-23; US2006-439873 Applic. Date: 2006-05-23; US2006-440410 Applic. Date: 2006-05-23; US2006-439874 Applic. Date: 2006-05-23; US2006-439884 Applic. Date: 2006-05-23; US20050684842P Applic. Date: 2005-05-25; US20050741673P Applic. Date: 2005-12-01; US20060788340P Applic. Date: 2006-03-31; US20060788249P Applic. Date: 2006-03-31

Inventor: SINGH NIKHILESH N [US]; PATHER SATHASIVAN I [US]

Title: INDULGENT GUM BASE AND CHEWING GUM COMPOSITIONS CONTAINING SAME

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 11/846728   Filing Date: 29/Aug/2007

Abstract:

The present invention includes gum base compositions and/or chewing gum compositions that impart a perceptible creaminess upon consumption. The gum base and/or chewing gum compositions include an elastomer, a gum resin or ester thereof and a low-melting pointing fat. In some embodiments, the gum base and/or chewing gum compositions may contain sufficient that to provide a creamy and/or juicy perception during consumption. In some embodiments, the gum base and/or chewing gum compositions may maintain sufficient fat to retain cohesive integrity during consumption. Also included are chewing gum products employing the gum base and/or chewing gum compositions, as well as methods of preparing and using same.

Priority: US20060840905P Applic. Date: 2006-08-29

Inventor: LUO SHIUH [US]; VISSCHER GLENN [US]; MCCORMICK DEMETRIUS TORINO [US]

Title: Dental Instrument

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927349   Filing Date: 29/Oct/2007

Abstract:

An active dental tool including a vibratory mechanism and a power storage reservoir. The vibratory mechanism includes an electrical motor and an elliptical load. The elliptical load is adapted to be rotated by the motor and to thereby impart an oscillatory motion to a tooth-contacting portion of the dental tool.

Priority: US2005-230710 Applic. Date: 2005-09-19; US20040612283P Applic. Date: 2004-09-21; US20040612006P Applic. Date: 2004-09-21; US20040624833P Applic. Date: 2004-11-03; US20040624840P Applic. Date: 2004-11-03

Inventor: HAYMAN ROBERT [US]; ROSENBLOOD KEN [US]

Title: SYSTEMS, KITS, AND METHODS FOR DETECTING CARIOGENIC BACTERIA AND ASSESSING RISK OF DENTAL CARIES

Applicant/Assignee: OREGON HEALTH AND SCIENCE UNIVERSITY

Application No.: 11/835411   Filing Date: 07/Aug/2007

Abstract:

Provided are systems, kits, and methods for the detection and identification of cariogenic bacteria in dental plaque and for assessing the risk in a patient of development dental caries based upon the presence of cariogenic bacteria.

Priority: US20060821672P Applic. Date: 2006-08-07

Inventor: MACHIDA CURTIS A [US]; MAIER TOM [US]

Title: COMPOUNDS THAT INHIBIT TRPV1 AND USES THEREOF

Applicant/Assignee: ABBOTT LABORATORIES

Application No.: 11/844712   Filing Date: 24/Aug/2007

Abstract:

Compounds of formula (I) wherein R3, R7, R9 and L are defined in the description are TRPV1 antagonists that exhibit low inhibitory activity against CYP3A4. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Priority: US20060840254P Applic. Date: 2006-08-25

Inventor: LEE CHIH-HUNG [US]; PERNER RICHARD J [US]; BROWN BRIAN S [US]; DARBYSHIRE JOHN [CH]

Title: Two-Step System For Improved Initial And Final Characteristics Of A Biomaterial

Applicant/Assignee:

Application No.: 10/577277   Filing Date: 29/Oct/2004

Abstract:

A two-step system for chemically bonded ceramic (CBC) materials, and especially a dental filling material or an implant material. The system includes an initial working part-system to provide for improved early-age properties and a second main system to provide for improved end-product properties including bioactivity. The systems interact chemically. The invention also relates to the powdered materials and the hydration liquid, respectively, as well as the formed ceramic material.

Priority: SE20030002844 Applic. Date: 2003-10-29; SE20040001026 Applic. Date: 2004-04-22; WO2004SE01577 Applic. Date: 2004-10-29

Inventor: HERMANSSON LEIF [SE]; ENGQVIST HAKAN [SE]; SPENGLER HAKAN [SE]

Title: Device For Filtering Second-Hand Smoke

Applicant/Assignee:

Application No.: 11/530233   Filing Date: 08/Sep/2006

Abstract:

A device for filtering second-hand smoke from a burning tobacco product includes a first chamber for receiving the lit end of the tobacco product. Users of the device can inhale smoke from the tobacco product through a first aperture in the first chamber, while a filter communicating with the first chamber filters smoke from the burning end of the tobacco product. A second chamber is configured to receive smoke and air exhaled by the user. The smoke is filtered by the second filter and the filtered air is passed through to the surrounding environment.

Priority:

Inventor: RICHARDS WILBUR [US]

Title: Cleaning and drying system for a personal hygiene device

Applicant/Assignee:

Application No.: 11/899774   Filing Date: 07/Sep/2007

Abstract:

An apparatus, system and method to clean and dry a personal hygiene device, such as a razor, tweezers, a comb, a toothbrush or other dental apparatuses, such as a dental pick. Typically, the system includes dryer generally coupled to a curved-wall chamber. The dryer generally includes a housing coupled to a duct, which, in turn is coupled to the curved-wall chamber. The housing includes a fan for pulling intake air into a housing via an air-intake. The housing further may include a heating element for heating air before entry into the curved-wall chamber. Thus, a personal hygiene device placed into a curved-wall chamber having a cleaning fluid can advantageously be cleaned and dried via circulating heated air and fluid within the curved-wall chamber under the circulation force of air provided by the fan.

Priority: US20060824860P Applic. Date: 2006-09-07

Inventor: RUFFIN STEPHEN [US]

Title: Method and apparatus for dispensing oral hygiene products

Applicant/Assignee:

Application No.: 11/518769   Filing Date: 11/Sep/2006

Abstract:

A method and apparatus for cleansing a person's mouth. One aspect is an apparatus comprising at least one teeth cleaning tool, a volume of mouth rinse and a container. The container comprises at least one first chamber that is liquid-tight and has the volume of mouth rinse disposed therein. The container further comprises at least one second chamber having the at least one teeth cleaning tool at least partially disposed therein.

Priority:

Inventor: KEISER RICHARD G [US]; ANGILERI PHILIP J [US]

Title: Dispensing Fluids From Containers Using Self Closing Valve, Typically Duckbill Type Valve

Applicant/Assignee:

Application No.: 11/575787   Filing Date: 11/Oct/2005

Abstract:

A dispenser for dispensing a fluid from a container T having an inlet for mounting to the container so as to receive therethrough the fluid, and an outlet which is adapted to open to release fluid therefrom when a predetermined pressure is applied to the fluid in the dispenser at the outlet, and to close to retain fluid in the dispenser at a pressure less than the predetermined pressure. A wall of resilient material at the outlet has one or more panels of elastomeric material provided therein, each panel being deformable to enable the adjacent resilient material to flex at the predetermined pressure and thus enable the outlet to open.

Priority: AU20040905861 Applic. Date: 2004-10-11; WO2005AU01578 Applic. Date: 2005-10-11

Inventor: WELLMAN CRAIG J [AU]

Title: Dentifrice Compositions

Applicant/Assignee: DEN-MAT HOLDINGS LLC

Application No.: 11/851715   Filing Date: 07/Sep/2007

Abstract:

Stain-removal, desensitizing, anti-tartar and anti-gingivitis dentifrice compositions. The dentifrices comprise a fluoride agent

an abrasive agent

a proteolytic agent

a foaming agent

a sweetening/flavoring agent

an emulsifying agent

either desensitizing, anti-tartar or anti-gingivitis agents or combinations thereof

and a delivery agent. The dentifrices are visually pleasing and impart a soothing sensation during and after brushing.

Priority: US20060843699P Applic. Date: 2006-09-12

Inventor: IBSEN ROBERT L [US]; MATHEWS ALAN B [US]

Title: Dental Whitening Compositions

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927471   Filing Date: 29/Oct/2007

Abstract:

A two-component whitening system has a de-sensitizing effect as well as re-mineralizing capability. The system may be an unfoamed, a foamed or a foamable composition. The system has a first component with at least one peroxide compound, at least one source of phosphate and at least one gelling agent

and a second component with at least one source of calcium, strontium and/or mixtures thereof. The second component may also contain at least one gelling agent, and the composition maybe present as a foam or is foamable. The composition may be packed in a two-compartment syringe.

Priority: US2005-271412 Applic. Date: 2005-11-09; US20040626407P Applic. Date: 2004-11-09; US20040631121P Applic. Date: 2004-11-26; US20050646309P Applic. Date: 2005-01-22; US20050653421P Applic. Date: 2005-02-15

Inventor: MACDONALD JEFF [US]; QUAN NANCY N [US]; HAYMAN ROBERT [US]

Title: Particulate form of a pharmaceutical composition which is easy to swallow

Applicant/Assignee:

Application No.: 11/516573   Filing Date: 07/Sep/2006

Abstract:

The present invention relates to a pharmaceutical composition for direct oral administration which is very easy to swallow especially for young children, comprising at least one pharmaceutically active compound. The pharmaceutical composition is present in the form of one or more particles. The particles comprise a core containing the active ingredient which has been provided with one or more coatings. The pharmaceutical composition is preferably administered in combination with a powder and/or granules which, when applied to the tongue, spontaneously generate additional saliva. With the extra saliva, the coated particles form a soft, smooth, but mechanically stable surface perceived as pleasant in the mouth within seconds so that they may be swallowed easily and practically in the right quantity with the extra saliva formed.

Priority:

Inventor: GRUBER PETER [DE]; KRAAHS PETER [DE]

Title: DUSTING COMPOSITIONS FOR CHEWING GUM PRODUCTS

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 11/840729   Filing Date: 17/Aug/2007

Abstract:

The present application relates to compositions for dusting chewing gum products and chewing gum products incorporating same. The dusting compositions have a managed release profile. The compositions generally include a dusting component, which is at least partially encapsulated with an encapsulating material. The compositions also may include an unencapsulated dusting component. The present invention also includes dusted chewing gum products, such as center-fill, compressed or candy gum, and methods of making same.

Priority: US2005-205874 Applic. Date: 2005-08-17; US2004-955149 Applic. Date: 2004-09-30; US2004-955225 Applic. Date: 2004-09-30; US2006-415043 Applic. Date: 2006-05-01; US2005-210954 Applic. Date: 2005-08-24; US2004-925822 Applic. Date: 2004-08-25; US2006-415044 Applic. Date: 2006-05-01; US2006-415006 Applic. Date: 2006-05-01; US2006-415012 Applic. Date: 2006-05-01; WO2006US19879 Applic. Date: 2006-05-19; US20060776699P Applic. Date: 2006-02-24; US20050683634P Applic. Date: 2005-05-23; US20050650758P Applic. Date: 2005-02-07; US20060838524P Applic. Date: 2006-08-17

Inventor: BOGHANI NAVROZ [US]; GEBRESELASSIE PETROS [US]; JANI BHARAT [US]; KABSE KISHOR [US]; GRANT R S [US]; KIEFER JESSE [US]; KUNCEWITCH THOMAS [US]; KRAMER COLLEEN [US]; ROBINSON MARY K [US]; SCHMITZ KRISTEN [US]; LUO SHIUH J [US]

Title: LIGHTED DENTAL CLEANER

Applicant/Assignee:

Application No.: 11/465603   Filing Date: 18/Aug/2006

Abstract:

A dental cleaning device includes a handle portion and a cover portion. The handle portion provides a dental cleaning tool, such as a dental pick or a dental scaler, and an illumination source, such as one or more light emitting diodes (LEDs). The illumination source directs light toward the end of the dental cleaning tool so that the light is always pointed exactly where it is needed during a dental cleaning procedure. The cover portion may include a mirror which further aids a user in viewing the dental cavity while using the dental cleaning tool. The cover portion is configured to attach to the handle portion to enclose the dental cleaning tool when the dental cleaning tool is not in use.

Priority:

Inventor: JANSHESKI JOHN M [US]; SHANKLE LEX [US]

Title: Tooth Whitening Lens with Bite Plate

Applicant/Assignee:

Application No.: 11/632561   Filing Date: 15/Jul/2005

Abstract:

A teeth whitening device having a lens which fits against the teeth. The lens has a casing containing a plurality of light emitting diodes which project light into the lens. The lens filters the light to produce a 430 to 450 nanometer blue light which is projected onto the surface of the teeth. When carbamide peroxide is placed on the surface of the teeth the blue light will activate the peroxide to whiten the teeth several shades within one hour without heating or sensitizing the teeth. The lens has a bite plate which a user bites down on to keep the lens in position against the teeth, leaving the user's hands free. The device and method are safe enough for use outside the dental office.

Priority: US20040588418P Applic. Date: 2004-07-16; WO2005US25295 Applic. Date: 2005-07-15

Inventor: OSBORN JOYCE A [US]

Title: Retracting Devices

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/929140   Filing Date: 30/Oct/2007

Abstract:

The present invention relates to a retracting device for retracting at least a portion of a user's mouth. The retracting device includes formations, which may be inter-engaging and/or non-inter-engaging with other dental tools or apparatus. The formations are adapted for repeatably positioning a subject's mouth with respect to a light system, and/or an imaging film, and/or a dental tray.

Priority: US2005-173297 Applic. Date: 2005-06-30; US20050220642F Applic. Date: 2005-01-04; US20050220680F Applic. Date: 2005-01-04; US20050220679F Applic. Date: 2005-01-04; US20050220712F Applic. Date: 2005-01-04; US20050232670F Applic. Date: 2005-06-22; US20050232671F Applic. Date: 2005-06-22; US20040585224P Applic. Date: 2004-07-02; US20050594327P Applic. Date: 2005-03-30; US20050594297P Applic. Date: 2005-03-25; US20050664696P Applic. Date: 2005-03-22; US20050658517P Applic. Date: 2005-03-03; US20050647580P Applic. Date: 2005-01-26; US20050647593P Applic. Date: 2005-01-26; US20050647612P Applic. Date: 2005-01-26; US20050647725P Applic. Date: 2005-01-26; US20050641462P Applic. Date: 2005-01-04; US20050641461P Applic. Date: 2005-01-04; US20050641469P Applic. Date: 2005-01-04; US20050641468P Applic. Date: 2005-01-04; US20040631267P Applic. Date: 2004-11-26; US20040604577P Applic. Date: 2004-08-25

Inventor: DORFMAN WILLIAM [US]; HAYMAN ROBERT [US]; ROSE ERIC P [US]; SCHROEDER DENNIS [US]; PIOREK STEVE [US]; QUAN NANCY N [US]; KARTEN STUART [US]; ROSENBLOOD KENNETH [US]

Title: Dental Matrix Devices And A Seamless, Single Load Cavity Preparation And Filling Technique

Applicant/Assignee:

Application No.: 11/834945   Filing Date: 07/Aug/2007

Abstract:

There are disclosed methods for the restoration of a decayed portion of a tooth, and dental matrices, dental wedges, interdental matrix stabilizers, dental separator rings, dental curing light devices, and kits that can be used in the methods for the restoration of a decayed portion of a tooth.

Priority: US20060844333P Applic. Date: 2006-09-13; US20070887291P Applic. Date: 2007-01-30

Inventor: CLARK DAVID J [US]

Title: Dental Kits And A Seamless, Single Load Cavity Preparation And Filling Technique

Applicant/Assignee:

Application No.: 11/834993   Filing Date: 07/Aug/2007

Abstract:

There are disclosed methods for the restoration of a decayed portion of a tooth, and dental matrices, dental wedges, interdental matrix stabilizers, dental separator rings, dental curing light devices, and kits that can be used in the methods for the restoration of a decayed portion of a tooth.

Priority: US20060844333P Applic. Date: 2006-09-13; US20070887291P Applic. Date: 2007-01-30

Inventor: CLARK DAVID J [US]

Title: Peptidic And Peptidoid Bradykinin B1 Receptor Antagonists And Uses Thereof

Applicant/Assignee: UNIVERSITE DE SHERBROOKE

Application No.: 11/660436   Filing Date: 19/Aug/2005

Abstract:

The present invention provides for new peptidic and peptidoid Bradykinin B1 receptor antagonists of formula (1) having good to excellent affinities and selectivity for the BKB1 receptor, and increased resistance to enzymatic degradation, superior pharmacokinetic properties, both in vitro and in vivo, with capability to significantly prevent and treat conditions wherein BKB1Rs are induced and over-expressed.

Priority: US20040602626P Applic. Date: 2004-08-19; WO2005CA01268 Applic. Date: 2005-08-19

Inventor: GUERIN BRIGITTE [CA]; BATTISTINI BRUNO [CA]; GOBEIL FERNAND [CA]; NANTEL FRANCOIS [CA]; NEUGEBAUER WITOLD [CA]; PLANTE GERARD [CA]; REGOLI DOMENICO [CA]; SIROIS PIERRE [CA]

Title: Automatic Plant for the Treatment and Packing of Meat Product

Applicant/Assignee:

Application No.: 11/596377   Filing Date: 12/May/2005

Abstract:

The invention relates to an automatic plant for the treatment and packing of meat product, comprising an injection station for injecting brine into a meat product, first and second maceration stations for macerating the injected meat product, and a packing station for packing the treated meat product. The injection station is connected to said first and second maceration stations by an accumulating and loading unit for accumulating meat product coming from the injection station and selectively loading it into the first and second maceration stations which are connected to the packing station by means of a transfer unit adapted for transferring the meat product from the first and second maceration stations to feed hoppers for feeding the packing station. The plant is controlled by computerized control.

Priority: WO2005ES00257 Applic. Date: 2005-05-12; ES20040001246 Applic. Date: 2004-05-14

Inventor: LAGARES COROMINAS NARCIS [ES]

Title: Protective face mask

Applicant/Assignee: KREAPS APS

Application No.: 11/896127   Filing Date: 29/Aug/2007

Abstract:

A protective face mask comprising: an eye-protecting shield made essentially from a plastics material, the eye-protecting shield being dimensioned to cover at least the eye portions of a human wearer, the eye-protecting shield having a perimeter defining a first surface facing the wearer's face, and a second surface facing away from the wearer's face

an adhesive forming an adhesive strip attached to the first surface of the eye-protecting shield for providing a substantially watertight and releasable sealing engagement between at least a portion of the perimeter forming an upper edge of the face mask and at least a portion of the skin of the wearer's face, wherein the upper part of the perimeter of the mask is provided with a continuous layer of adhesive along the perimeter, and the lower part of the perimeter of the mask is free of adhesive, the lower part of the perimeter forms a bottom edge of the mask being provided with at least one part forming a projection offset from the centre line of the mask, and wherein the mask extends along the contour of the wearer's face from the forehead to cheekbones and the lower perimeter thereof extends above the mouth provides a comfortable and flexible mask without the need for straps,

elastic bands or side bars, avoids pressure on the skin in the contact zone, allows free eye movement and airflow and minimizes the formation of dew.

Priority: EP20060017965 Applic. Date: 2006-08-29; US20060840691P Applic. Date: 2006-08-29

Inventor: KAYEROD HELLE [DK]

Title: Stripe removal system

Applicant/Assignee:

Application No.: 11/835642   Filing Date: 08/Aug/2007

Abstract:

A system for removing paint and other coatings from hard surfaces is mounted on a truck for over-the-road travel. The truck bed carries a high power vacuum pump, a self propelled tractor with an attached blast head, a liquid reservoir, a sump or vacuum tank, and a ramp for loading the tractor. The reservoir is connected to a low pressure pump that transfers water to the high pressure pump. The high pressure pump is connected to the blast head by a high pressure hose. A vacuum hose is connected to the sump which has an internal enclosure for separating the waste materials from the liquid for easy dumping of semi dried materials.

Priority: US2004-884643 Applic. Date: 2004-07-02

Inventor: CROCKER JAMES P [US]

Title: Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof

Applicant/Assignee: FOAMIX LTD

Application No.: 11/900072   Filing Date: 10/Sep/2007

Abstract:

Vitamin and flavonoid containing compositions are provided that are stable to degradation. Stabilized compositions include one or more features including a hygroscopic solvent at a sufficient concentration to provide an Aw value of the hygroscopic vitamin and or flavonoid containing composition of less than 0.9, antioxidant flavonoids that are preferentially oxidized before the vitamin, preservatives, and hydrocarbon propellants selected to reduce the oxidation potential of the composition.

Priority: US2006-430599 Applic. Date: 2006-05-09; US2004-835505 Applic. Date: 2004-04-28; US20060843140P Applic. Date: 2006-09-08; US20060784793P Applic. Date: 2006-03-21; US20050679020P Applic. Date: 2005-05-09; US20030530015P Applic. Date: 2003-12-16; US20030492385P Applic. Date: 2003-08-04

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; EINI MEIR [IL]; BERMAN TAL [IL]; SCHUZ DAVID [IL]

Title: METHOD OF INHIBITING BACTERIAL GROWTH AND BIOFILM FORMATION WITH NATURAL QUORUM SENSING PEPTIDES

Applicant/Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA

Application No.: 11/561275   Filing Date: 17/Nov/2006

Abstract:

Methods for selectively manipulating a growth rate of a selected bacterium comprising the step of contacting the selected bacterium with a predetermined amount of a quorum sensing molecule to affect a change in the growth rate of the selected bacterium, wherein the quorum sensing molecule is species specific, and the change in the growth rate is dependent on the amount of quorum sensing molecule in a dose-dependent fashion. Also provided are methods for treating or protecting against bacterial infections by utilizing the dose-dependent response of bacterial quorum sensing systems. The methods can be applied to a wide range of bacteria species including Streptococci, Staphylococci, and Bacilli. Compositions, medicaments and oral formulations for use with the methods are also disclosed.

Priority: US20050738361P Applic. Date: 2005-11-17

Inventor: GOODMAN STEVEN D [US]; KAY OLGA [US]; SHI WENYUAN [US]; QL FENGXIA [US]

Title: Pharmaceutical Compositions Containing Botulinum Neurotoxin A2

Applicant/Assignee:

Application No.: 11/659448   Filing Date: 03/Aug/2005

Abstract:

A composition, medicament or use, comprising or consisting of botulinum toxin type A2 and a surfactant, having one or more or all of the characteristics select from the group consisting of

(a) a much longer duration of action

(b) a much faster rate of onset of muscular paralysis

(c) a significantly greater intramuscular safety margin

(d) a selective action on inhibition of skeletal muscle contraction

(e) a selective action on inhibition of pain-related (nociceptive) nerve cell function: Wherein each characteristic is determined comparative to the same characteristic effect of botulinum toxin type A1.

Priority: GB20040017367 Applic. Date: 2004-08-04; GB20040021290 Applic. Date: 2004-09-24; GB20040021288 Applic. Date: 2004-09-24; GB20040023952 Applic. Date: 2004-10-28; GB20040023953 Applic. Date: 2004-10-28; WO2005GB03036 Applic. Date: 2005-08-03

Inventor: PANJWANI NAVEED [GB]; WEBB PAUL [GB]; PICKETT ANDY [GB]

Title: Device for treatment of disorders in the oral cavity with nitric oxide, and manufacturing process for the same

Applicant/Assignee:

Application No.: 11/891674   Filing Date: 10/Aug/2007

Abstract:

A device and method for therapeutical treatment of disorders in the oral cavity and a process for manufacturing of said device is disclosed. The device comprises a nitric oxide (NO) eluting polymer. The nitric oxide (NO) eluting polymer is configured to elute a therapeutic dosage of nitric oxide (NO) when used in the oral cavity. The device allows for target treatment of infections or wounds in the oral cavity. The device comprising the nitric oxide (NO) eluting polymer is arranged to contact an infected area in the oral cavity, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said therapeutic dosage of nitric oxide (NO).

Priority: EP20050002937 Applic. Date: 2005-02-11; WO2006EP50888 Applic. Date: 2006-02-13; US20050652758P Applic. Date: 2005-02-14

Inventor: PETERS TOR [SE]

Title: Method for preparing solid dosage forms that form a paste, cream or gel when diluted for final use

Applicant/Assignee:

Application No.: 11/901120   Filing Date: 14/Sep/2007

Abstract:

Solid compositions capable of forming a paste, cream or gel suitable for use as a personal hygiene product when diluted with a liquid are disclosed. Methods of making and using solid compositions capable of forming a paste, cream or gel suitable for use as a personal hygiene product when diluted with a liquid are also disclosed.

Priority: US20060825698P Applic. Date: 2006-09-14

Inventor: MOORE RYAN G [US]

Title: VITAMIN D COMPOSITIONS AND METHOD OF ADMINISTRATION TO A HUMAN BEING

Applicant/Assignee:

Application No.: 11/674234   Filing Date: 13/Feb/2007

Abstract:

Composition of vitamin D in medium-chain triglycerides and use thereof in delivering a nutritional or therapeutic amount of vitamin D to a human being, particularly, an infant. The compositions are applied to an object, such as skin or in the case of an infant to a woman's nipple or pacifier from which the infant sucks off the composition. The method provides a more suitable, safer and efficient way of providing the human being with vitamin D. The compositions further comprise a free fatty acid and/or monoglyceride, oxidant preservative and, optionally, other vitamins.

Priority: CA20062558202 Applic. Date: 2006-09-14

Inventor: VIETH REINHOLD W [CA]; VIETH ELAINE [CA]

Title: Palladium-cobalt based alloys and dental articles including the same

Applicant/Assignee: IVOCLAR VIVADENT, INC

Application No.: 11/892933   Filing Date: 28/Aug/2007

Abstract:

An alloy is provided based on a palladium-cobalt binary system, has a coefficient of thermal expansion (CTE) of about 14.0 to about 15.5 and may include one or more of the following additive metals: aluminum, boron, chromium, gallium, lithium, rhenium, ruthenium, silicon, tantalum, titanium, and tungsten.

Priority: US20060844672P Applic. Date: 2006-09-15

Inventor: DASGUPTA TRIDIB [US]; INGERSOLL CLYDE [US]; TYSOWSKY GEORGE [US]

Title: Dispenser for dental compositions

Applicant/Assignee: BISCO, INC

Application No.: 11/522825   Filing Date: 14/Sep/2006

Abstract:

The present invention relates to an apparatus for providing specifically metered doses of at least two flowable dental materials in desired ratios to one another. In particular, the present invention allows for controlled metering and dispensing of two or more flowable dental substances which when subsequently mixed form a dental bonding composition, dental adhesive, dental cement, or other dental restorative or preparative materials.

Specifically, one embodiment of the present invention utilizes a multi-rack system as well as a drive spring action to provide a substantial mechanical advantage to the user such that a relatively long throw of the dispensing button creates a relatively short, metered distance of movement of the multiple racks and corresponding pistons in the each lumen of a cartridge containing the component of the desired dental composition, allowing for small, metered doses of each flowable dental component to be dispensed from the apparatus in the proper proportions.

Priority:

Inventor: MULHAUSER PAUL [US]; KIRK KARL D [US]; CZARNECKI DAVID [US]; NAGEL RICHARD [US]

Title: Disposable dental prophylaxis apparatus capable of discharging predetermined amount of dentifrice material therefrom

Applicant/Assignee:

Application No.: 11/602094   Filing Date: 21/Nov/2006

Abstract:

The present invention relates to a disposable dental prophylaxis apparatus capable of discharging a predetermined amount of dentifrice material therefrom, including: a housing having a drain hole adapted for discharging a dentifrice material therefrom, a tube room adapted for mounting a dentifrice material-charging tube therein, and a link room having a plurality of teeth formed along the both inner wall surfaces for adjustably discharging the dentifrice material in predetermined amounts from the tube

a wheel gear having a drain hole adapted for inducing the dentifrice material flowing from the drain hole of the housing to a wheel cup adapted for rubbing against a patient's tooth

the wheel cup having a drain hole formed for receiving the dentifrice material induced from the drain hole of the wheel gear

the tube adapted to be charged with the dentifrice material and having a plurality of folds adapted to be compressed gradually as the dentifrice material is discharged therefrom in the predetermined amounts

and a link adapted for compressing the tube such that the dentifrice material is discharged from the tube.

Priority: KR20060089786 Applic. Date: 2006-09-15

Inventor: LEE KWANG S [US]

Title: Method for Forming Polychromatic Pressable Porcelain Dental Restoration

Applicant/Assignee: DEN-MAT CORPORATION

Application No.: 11/840803   Filing Date: 17/Aug/2007

Abstract:

A method for forming a polychromatic pressable porcelain dental restoration. A wax model of the dental restoration is prepared as is commonly used in the lost wax technique. Chards or pieces of porcelain are embedded into the wax model. The porcelain embedded wax model is then used in the common pressable porcelain technique to form a polychromatic porcelain dental restoration with natural tooth shading.

Priority: US20060841539P Applic. Date: 2006-09-01

Inventor: RICKS SEAN [US]

Title: Palladium-cobalt based alloys for dental prestheses including porcelain fused to metal

Applicant/Assignee: IVOCLAR VIVADENT, INC

Application No.: 11/543917   Filing Date: 06/Oct/2006

Abstract:

An alloy s provided for dental prostheses including porcelain fused to metal (PFM) restorations. The alloy is grey in color with an oxide coating for bonding porcelain to the oxidized cast alloy substrate. The alloy has suitable mechanical properties for cast prostheses and for the support of the porcelain and is readily polished to a bright sheen. The alloy is based on a palladium-cobalt binary system, has a coefficient of thermal expansion (CTE) in the range of about 14.0 to 15.3 and may include one or more of the following additive metals: aluminum, boron, chromium, gallium, lithium, rhenium, ruthenium, silicon, tantalum, titanium, and tungsten.

Priority: US20060844672P Applic. Date: 2006-09-15

Inventor: DASGUPTA TRIDIB [US]; INGERSOLL CLYDE [US]; TYSOWSKY GEORGE [US]

Title: Dental Composition Containing Unsaturated Carbosilane Containing Components

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/572071   Filing Date: 14/Jul/2004

Abstract:

The invention relates to a dental composition comprising a) carbosilane containing component (A) comprising at least 1 Si-Aryl bond, at least 1 silicon atom, at least 2 unsaturated moiety, no Si-Oxygen bond, b) Si-II functional component (B), c) initiator (C), d) optionally filler (D), and e) optionally component (E) selected from modifiers, dyes, pigments, thixotropic agents, flow improvers, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavourings.

Priority: WO2004EP07788 Applic. Date: 2004-07-14

Inventor: BISSINGER PETER [DE]; ECKERT ADRIAN S [DE]; HECHT REINHARD [DE]; HOHEISEL UWE H [DE]

Title: Energetically activated biomedical nanotheurapeutics integrating dental and medical treatments and procedures

Applicant/Assignee:

Application No.: 11/895404   Filing Date: 24/Aug/2007

Abstract:

A method that includes the following effects: the ability to expand, porositize, clean, decontaminate, debride, break-down and/or destroys, or aids and accentuates the dissolution or extraction of biological structures, nerves and tissues. The methodology uses nano-technology and/or other chemistries may or may not be excited by energy sources to expand and porositize the tissue, which enhances the penetration and effectiveness and acceleration of subsequent chemical, mechanical, and/or procedural steps in the protocol or process. Furthermore, the method includes the ability to associate with and/or initiate in the reconstructive growth and healing process associated with healthy tissue after surgery and/or the ability to destroy diseased or necrotic tissues or cells. The method also includes the ability to begin, construct or stage the activation of cells and/or tissues, including the area of transplantation and use in stem or primordial cell accentuation, their attachment and/or stimulation for growth and differentiation.

Priority: US20060840282P Applic. Date: 2006-08-24

Inventor: DIVITO ENRICO E [US]; GLOVER DOUGLAS L [US]; TUBBS KEMMONS [US]

Title: TRIPHENYLPHOSPHINE OXIDE DERIVATIVES AND USES THEREOF

Applicant/Assignee: REDPOINT BIO CORPORATION

Application No.: 11/856518   Filing Date: 17/Sep/2007

Abstract:

The present invention is directed to the use of a compound having the formula wherein R<1>, R<2>, R<3>, m, n and p are defined herein. The compounds of the present invention are useful as inhibitors of certain taste perceptions and functions. The invention is also directed to compositions comprising a compound according to the above formula.

Priority: US20060844657P Applic. Date: 2006-09-15

Inventor: PALMER R KYLE [US]; BRYANT ROBERT W [US]; SPROUS DENNIS [US]

Title: MEDICAL DEVICES HAVING ALLOY COMPOSITIONS

Applicant/Assignee: BOSTON SCIENTIFIC SCIMED, INC

Application No.: 11/780060   Filing Date: 19/Jul/2007

Abstract:

A medical device includes an alloy having a microstructure that provides desirable properties. The alloy can be a eutectoid composition of e.g. titanium as a major constituent and any combination of iridium, platinum, chromium, gold, silver, bismuth, manganese, palladium, cobalt, copper, iron, and/or nickel as a minor constituent, wherein the alloy forms at least a portion of the medical device.

Priority: US20060844897P Applic. Date: 2006-09-15

Inventor: CAMBRONNE MATTHEW [US]

Title: Dispensing Utensil

Applicant/Assignee:

Application No.: 11/771372   Filing Date: 29/Jun/2007

Abstract:

A dispensing utensil 10 comprising: a handle portion 11

an implement portion 12

a cavity 15 for storing dispensable contents, the cavity 15 defined by a first wall means 13, 14 and a second wall means 19 closing the cavity 15

characterised in that a first portion 20 of the first wall means 13, 14 is openable about a hinge formed by the second wall means 19 , thereby allowing the contents to be dispensed.

Priority: WO2004AU01818 Applic. Date: 2004-12-30; AU20040100000 Applic. Date: 2004-01-02

Inventor: TEYS BRADLEY D [AU]; BEVAN GLENN [AU]; MOBBS KEVIN J [AU]

Title: Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules

Applicant/Assignee:

Application No.: 11/703610   Filing Date: 06/Feb/2007

Abstract:

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.

Priority: US2003-658834 Applic. Date: 2003-09-08; US20030457135P Applic. Date: 2003-03-21; US20020409898P Applic. Date: 2002-09-09

Inventor: GANTIER RENE [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]; GUYON THIERRY [FR]

Title: Dental Whitening Systems

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927207   Filing Date: 29/Oct/2007

Abstract:

A system and method for tooth whitening are disclosed wherein at least one peroxide-containing gel and at least one transition metal compound- containing gel, particularly at least one lower atomic number transition metal compound, more particularly at least a ferrous compound including gluconate, sulfate, nitrate, acetate or mixtures thereof, are applied to a patient's mouth. Gelling agent is also included. The activation of the peroxide whitens the patient's teeth. The system may be used with or without the application of light. The system further provides an additional gel including a sensitivity reduction compound including potassium nitrate, sodium nitrate or mixtures thereof for possible sensitivity treatment if needed.

Priority: US2005-271283 Applic. Date: 2005-11-09; US20040626407P Applic. Date: 2004-11-09; US20040631121P Applic. Date: 2004-11-26; US20050653421P Applic. Date: 2005-02-15

Inventor: MACDONALD JEFF [US]; LEE ANGELA J [US]; QUAN NANCY N [US]

Title: Methods of drug delivery using sulphated chitinous polymers

Applicant/Assignee:

Application No.: 11/899172   Filing Date: 04/Sep/2007

Abstract:

The present invention provides methods and compositions for delivering a therapeutic agent across a membrane that has limited permeability for the therapeutic agent. The method includes delivering the therapeutic agent to the membrane in a composition which includes a sulphated chitinous polymer as a primary carrier.

Priority: US2002-224173 Applic. Date: 2002-08-20

Inventor: KYDONIEUS AGIS [US]; ELSON CLIVE [CA]; THANOU MAYA [GR]

Title: Pharmaceutical compounds

Applicant/Assignee: PIRAMED LIMITED GENENTECH, INC

Application No.: 11/789468   Filing Date: 24/Apr/2007

Abstract:

Compounds of Formulae Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Priority: US20060795048P Applic. Date: 2006-04-26

Inventor: FOLKES ADRIAN [GB]; SHUTTLEWORTH STEPHEN [GB]; CHUCKOWREE IRINA [GB]; OXENFORD SALLY [GB]; WAN NAN CHI [GB]; CASTANEDO GEORGETTE [US]; GOLDSMITH RICHARD [US]; GUNZNER JANET [US]; HEFFRON TIM [US]; MATHIEU SIMON [US]; OLIVERO ALAN [US]; SUTHERLIN DANIEL P [US]; ZHU BING-YAN [US]

Title: Pharmaceutical compounds

Applicant/Assignee: PIRAMED LIMITED

Application No.: 11/789423   Filing Date: 24/Apr/2007

Abstract:

A thienopyrimidine of formula (I): and the pharmaceutically acceptable salts thereof have activity as inhibitors of PI3K with selectivity for the P110alpha subtype, and may be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour, particularly those associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.

Priority: US20060794966P Applic. Date: 2006-04-26

Inventor: CHUCKOWREE IRINA [GB]; FOLKES ADRIAN [GB]; HANCOX TIM [GB]; SHUTTLEWORTH STEPHEN [GB]

Title: Polymerizable compositions with acylgermanes as initiatiors

Applicant/Assignee: IVOCLAR VIVADENT AG

Application No.: 11/730533   Filing Date: 02/Apr/2007

Abstract:

Composition with at least one polymerizable binder and a polymerization initiator, which contains at least one acylgermane according to general Formula (I), in which R<0 >is a substituted or unsubstituted C1-18-alkyl radical or an acyl group

R<1 >and R<2 >are H, an acyl group or have one of the meanings given for R<3>

R<3 >is a branched or linear C1-18-alkyl radical which can be unsubstituted or substituted one or more times by -O-, -NH-, -NR-, -S- or interrupted by other groups, trimethylsilyl, hal-(CH3)2Si-[OSi(CH3)2]r<->, (CH3)3Si-[OSi(CH3)2]r-, -COOH, -COO-R<10>, -CO-NR<11>R<12>, -CO-vinyl, -CO-phenyl, phenyl-C1-4-alkyl, phenyl, naphthyl or biphenyl, C5-12 cycloalkyl, a 5 or 6-membered O, S or N-containing heterocyclic ring, halogen, OH, an aromatic C6-30 radical which can be substituted or unsubstituted and/or interrupted by O, S or -NR-, or a branched, cyclic or linear C1-20 alkyl, -alkenyl, -alkoxy or -alkenoxy radical

m is 1, 2 or 3

n is 0 or 1 and p is 0 or 1

and the use of acyl germanes of Formula (I) for example as initiator for radical polymerization.

Priority: EP20060121333 Applic. Date: 2006-09-27

Inventor: MOSZNER NORBERT [DE]; SALZ ULRICH [DE]; FISCHER URS KARL [CH]; LISKA ROBERT [AT]; GRUBER HEINRICH [AT]; GANSTER BEATE [AT]

Title: Low stress flowable compositions

Applicant/Assignee:

Application No.: 11/811264   Filing Date: 08/Jun/2007

Abstract:

A photopolymerizable and photocleavable (P&P) resin monomer is derived from a reactive photoresponsible moiety via various linkages to form photopolymerizable monomers and/or oligomers.

Priority: US20060812541P Applic. Date: 2006-06-09

Inventor: JIN XIAOMING [US]; HAMMESFAHR PAUL D [US]

Title: CARABINER BOTTLE CLOSURE

Applicant/Assignee:

Application No.: 11/538047   Filing Date: 02/Oct/2006

Abstract:

A closure for removably sealing a container and for attaching to external articles having an external hooking device. The closure includes a container cap configured to removably engage the container and having a strip engaging portion formed proximate an end of the cap. The closure includes an attachment member that has a resilient hooking strip extending from the lid to define a hooking aperture therebetween. The attachment member has a cap engaging portion formed adjacent an end thereof and releasably engaged to the strip engaging portion. The engaging portions are configured such that the cap engaging portion is releasable from engagement by applying disengaging force upon any portion of the hooking strip.

Priority:

Inventor: YELLAND WILLIAM [CA]

Title: Dental filing tool

Applicant/Assignee:

Application No.: 11/982117   Filing Date: 01/Nov/2007

Abstract:

A dental filing tool and method for use includes providing a unitary injection-molded handle with integral finger pads, indicia markings, and an abrasive filing strip embedded into the handle vertical arms

inserting the tool between teeth to cut and file restorations

and, disposing after use. A method for making a dental filing tool is provided, including the steps: selecting a strip

providing the strip with abrasive means

providing the strip with mounting holes

providing an injection mold with a horizontal and first and second vertical arm channels, each of the vertical arm channels having flattened opposing outer edges to form integral finger pads

and, first and second mounting pins spaced distally to hold the strip in tension

mounting the strip onto the pins within the mold

injecting plastic by injection molding means to form the dental filing tool

cooling the dental filing tool until resilient

and, removing the filing tool.

Priority: US2004-945033 Applic. Date: 2004-09-21

Inventor: KIM DANIEL S [US]

Title: Methods of using combinations of siRNAs for treating a disease or a disorder, and for enhancing siRNA efficacy in RNAi

Applicant/Assignee:

Application No.: 11/481879   Filing Date: 06/Jul/2006

Abstract:

The present invention provides methods for treating diseases or disorders, and methods for enhancing siRNA efficacy in RNAi, including administering to a subject or a biological system one or more siRNAs capable of down regulating the expression of one or more target genes and one or more siRNAs capable of down regulating the expression of one or more negative regulators of RNAi. The present invention also provides compositions including one or more siRNAs, or precursors thereof, capable of down regulating the expression of one or more target genes and comprising one or more siRNAs, or precursors thereof, capable of down regulating the expression of one or more negative regulators of RNAi.

Priority:

Inventor: HUANG WEIDA [CN]; HONG JIE [CN]; QIAN ZHIKANG [CN]

Title: DENTAL RESTORATIVE MATERIAL COMPOSITION

Applicant/Assignee: GC CORPORATION

Application No.: 11/858403   Filing Date: 20/Sep/2007

Abstract:

To provide a dental restorative material composition using an organic-inorganic composite filler having excellent surface smoothness like a natural tooth, low polymerization shrinkage, excellent X-ray contrast imaging property, similar transparency to that of a natural tooth, and no variation of transparency before and after the composition is hardened, the dental restorative material composition includes (a) a (meth)acrylate monomer, (b) an organic-inorganic composite filler having an average particle diameter of 5 to 50 mum which is made by mixing a (meth)acrylate monomer and a fine particle filler having an average primary particle diameter of 0.005 to 0.3 mum and having X-ray impermeability, (c) a fine particle filler having an average primary particle diameter of 0.005 to 0.04 mum, and (d) a photopolymerization initiator.

Priority: JP20060265998 Applic. Date: 2006-09-28

Inventor: FUSEJIMA FUTOSHI [JP]; JIMBO NAOKO [JP]; KAGA SHINJI [JP]

Title: MOUTH GUARD COMPOSITION

Applicant/Assignee: GC CORPORATION

Application No.: 11/859341   Filing Date: 21/Sep/2007

Abstract:

A mouth guard composition comprises 39 to 98% by weight of styrene block copolymer

1 to 60% by weight of one or more kinds of thermoplastic resins selected from the group consisting of aliphatic cyclic saturated hydrocarbon resin, terpene resin, aliphatic petroleum resin and ester gum

and 0.1 to 40% by weight of one or more kinds of waxes selected from the group consisting of mineral wax, synthetic wax, plant wax, and animal wax, said composition further comprising 0.1 to 20% by weight of polyolefin resin, thereby providing the mouth guard composition which is not largely distorted when extremely strong impact force is applied thereto during the use of the mouth guard and can protect teeth and jaws, and little wearing is caused when repetitive force is applied.

Priority: JP20060269399 Applic. Date: 2006-09-29

Inventor: KAMOHARA HIROSHI [JP]; FUKUSHIMA SHOUICHI [JP]; TSUNOOKA MIYUKI [JP]

Title: Mouth cleaning device

Applicant/Assignee: MATSUSHITA ELECTRIC WORKS, LTD

Application No.: 11/905640   Filing Date: 03/Oct/2007

Abstract:

A mouth cleaning device includes: a head portion provided with bristles and an electrode

and a handle portion provided with an electrode. In the mouth cleaning device, when an electric circuit is formed from one electrode to the other electrode via a human body by application of a voltage to the electrodes, a pulse current having a frequency of about 4000 Hz to about 15000 Hz flows therein.

Priority: JP20060275682 Applic. Date: 2006-10-06

Inventor: TANIGUCHI SHINICHI [JP]; KISHIMOTO SUEHISA [JP]; KUNITA TOMOHIRO [JP]; SHIMIZU HIROAKI [JP]

Title: Controlled Long Acting Release Pharmaceutical Preparation For Use In The Oral Cavity

Applicant/Assignee:

Application No.: 11/794168   Filing Date: 28/Dec/2005

Abstract:

The present invention relates to a controlled long acting release pharmaceutical preparation for use in the oral cavity either for the treatment of diseases of the oral cavity or

for releasing said pharmaceutical preparation into said oral cavity. Said pharmaceutical preparation comprises at least a therapeutic agent, a binder and a lubricant (hereinafter "the preparation" or "the pharmaceutical preparation").

Priority: IL20050166114 Applic. Date: 2005-01-03; WO2005IL01385 Applic. Date: 2005-12-28

Inventor: SELA YORAM [IL]

Title: Composition and method for raising blood glucose level

Applicant/Assignee:

Application No.: 11/544530   Filing Date: 06/Oct/2006

Abstract:

Composition, non-aerosol dispenser containing the composition, and method of raising the blood glucose level of an individual comprising administering an effective amount of the composition to an oral mucosa of the individual. The composition comprises: a. an effective amount of glucose, b. an effective amount of at least one absorption enhancer chosen from lecithin, hyaluronic acid, glycolic acid, lactic acid, chamomile extract, cucumber extract, oleic acid, linoleic acid, linolenic acid, monoolein, monooleates, monolaurates, borage oil, evening primrose oil, menthol, trihydroxy oxo cholanyl glycine, glycerin, polyglycerin, lysine, polylysine, triolein, polyoxyethylene ethers, polidocanol alkyl ethers, chenodeoxycholate, deoxycholate, alkali metal salicylate, pharmaceutically acceptable edetate, and pharmaceutically acceptable salts and analogues thereof, and c. an effective amount of a pharmaceutically acceptable carrier, wherein the composition is free of any active pharmaceutical agents.

Priority:

Inventor: GLUSKIN ANNA E [CA]; QAZI MUHAMMAD WASEEM T [CA]

Title: SILICA-COATED METAL OXIDE SOLS HAVING VARIABLE METAL OXIDE TO SILICA RATIO

Applicant/Assignee:

Application No.: 11/538477   Filing Date: 04/Oct/2006

Abstract:

This invention provides metal-rich siliceous compositions and methods of preparing such compositions. The compositions have comprehensibly variable and controllable metal oxide to silica ratios, surface morphology, porosity, and surface area. The method includes preparing a silicic acid, a metal oxide dispersion, and a basic heel solution. The silicic acid and metal oxide dispersion are mixed to create a blend and the blend is controllably added to the basic heel solution to form a siliceous material including colloidal silica-coated metal oxide particles. Factors such as type of silicic acid, concentration and type of metal oxide, and reaction conditions determine properties, including surface morphology and porosity, of the siliceous material

Priority:

Inventor: ORTIZ C YOLANDA [US]

Title: Oxime Derivatives And Use Thereof As Latent Acids

Applicant/Assignee: CIBA SPECIALTY CHEMICALS CORPORATION

Application No.: 11/632687   Filing Date: 11/Jul/2005

Abstract:

The invention pertain to novel photoacid generator compounds of the formula I, II or III wherein R1 is for example C1-C18alkylsulfonyl or phenylsulfonyl, phenyl-C1-C3alkylsulfonyl, naphthylsulfonyl, anthracylsulfonyl or phenanthrylsulfonyl, all optionally substituted, or R1 is a group X1, X2 and X3 independently of each other are O or S

R'1, is e.g. phenylenedisulfonyl, naphthylenedisulfonyl, diphenylenedisulfonyl, or oxydiphenylenedisulfonyl, all optionally substituted

R2 is halogen or C1-C10haloalkyl

X is halogen

Ar1 is for example biphenylyl or fluorenyl, or is substituted naphthyl

Ar'1 is heteroarylene, optionally substituted

R8, R9, R10 and R11 for example are C1-C6alkyl which is unsubstituted or substituted by halogen

or R8, R9 and R10 are phenyl which is unsubstituted or substituted by C1-C4alkyl or halogen

or R10 and R11 together are 1,2-phenylene or C2-C6alkylene which is unsubstituted or substituted by C1-C4alkyl or halogen.

Priority: EP20040103453 Applic. Date: 2004-07-20; WO2005EP53296 Applic. Date: 2005-07-11

Inventor: YAMATO HITOSHI [JP]; ASAKURA TOSHIKAGE [JP]; HINTERMANN TOBIAS [CH]

Title: Methods for making provisional and long-term dental crowns and bridges

Applicant/Assignee:

Application No.: 11/805672   Filing Date: 24/May/2007

Abstract:

The invention provides methods of making provisional and long-term dental restorations, particularly dental veneers, crowns and bridges. In one embodiment, the restoration can be fabricated indirectly by a dental laboratory. In another version, a dental practitioner can make the restoration chairside for a patient in a dental office. A polymerizable dental composite material, which is dimensionally shape-stable in its uncured state, is used to make the restoration. The material includes a polymerizable acrylic compound, polymerization initiator system capable of being activated by light or heat, and a filler material. The resulting dental restoration has good aesthetics, mechanical strength, and margins and contacts.

Priority: US20060848117P Applic. Date: 2006-09-29

Inventor: SUN BENJAMIN J [US]; YOUNG ANDREW M [US]; LICHKUS ANDREW M [US]

Title: Dental Compositions Containing Oxirane Monomers

Applicant/Assignee:

Application No.: 11/571943   Filing Date: 13/Jul/2005

Abstract:

Epoxy-functional ether monomers (i.e., oxirane monomers) for use in oxirane-based dental compositions.

Priority: US20040587977P Applic. Date: 2004-07-14; WO2005US24822 Applic. Date: 2005-07-13

Inventor: MADER ROGER M [US]; JACOBS DWIGHT W [US]; ECKERT ADRIAN S [DE]

Title: Method and apparatus for non -invasive rinse diagnosis and monitoring of periodontal diseases

Applicant/Assignee:

Application No.: 11/543202   Filing Date: 05/Oct/2006

Abstract:

An assay test kit is used in a mouth rinse sample collection procedure involving collecting a mouth rinse sample from a patient. A neutrophil reactant diagnostic reagent is delivered to the rinse sample immediately after collection. Diagnostic reagents containing diammonium salts that are reactive with neutrophil enzymes are added to the sample to produce visually discernable colour change in the solution after a selected period of time. Most preferably, the reagents are selected to produce a colour change after a period of time. The reaction is then measured by comparing the resulting sample colour change by eye or mechanically to a standardized colour chart/swatch that correlates with predetermined neutrophil concentrations and/or periodontal disease levels.

Priority:

Inventor: GLOGAUER MICHAEL [CA]

Title: Method for Making a Bag

Applicant/Assignee:

Application No.: 11/793728   Filing Date: 13/Dec/2005

Abstract:

A method for making bags from flexible plastic film comprises the steps of feeding a sheet of plastic film

making at least one indented pleated portion in the film and, in particular, a first and a second indented pleated portion ( 916, 918 ), and e forming the film into a tubular shape. According to the method of the invention, means are provided for sealing the respective end ( 916', 918' ) of the pleated portion, said means being in the form of a respective sealing band ( 942 ).

Priority: IT2004MI02491 Applic. Date: 2004-12-23; IT2005BO00265 Applic. Date: 2005-04-21; WO2005IB03954 Applic. Date: 2005-12-13

Inventor: REGGI MARCO [IT]

Title: Coloring of ceramics by atmospheric control

Applicant/Assignee: PENTRON CERAMICS, INC

Application No.: 11/889945   Filing Date: 17/Aug/2007

Abstract:

Methods of forming a colored ceramic body or dental article are described that include: (a) forming a body from a ceramic-containing powder

(b) shaping the body into a desired shape

and (c) firing the shaped body in an atmosphere comprising at least one coloring agent. Methods of forming a fully dense ceramic body that lacks discoloration, are also described which include: (a) forming a body from a ceramic-containing powder

(b) shaping the body into a desired shape

(c) placing the shaped body in a firing atmosphere containing at least one impurity that promote discoloration of the ceramic body

(d) placing the ceramic body in proximity to an atmosphere powder

and (e) firing the shaped body in proximity to an atmosphere powder

wherein the atmosphere powder acts as at least one of a barrier and a getter for the at least one impurity.

Priority: US20060838375P Applic. Date: 2006-08-18

Inventor: KHAN AJMAL [US]; BRODKIN DMITRI G [US]

Title: Heteroaryl Substituted Quinolin-4-Ylamine Analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/795269   Filing Date: 13/Jan/2006

Abstract:

Heteroaryl substituted quinolin-4-ylamine analogues of Formula I are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20050644503P Applic. Date: 2005-01-14; WO2006US01345 Applic. Date: 2006-01-13

Inventor: CALDWELL TIMOTHY M [US]; CHENARD BERTRAND L [US]; HODGETTS KEVIN J [US]

Title: Mouth cleaning device

Applicant/Assignee: MATSUSHITA ELECTRIC WORKS, LTD

Application No.: 11/905641   Filing Date: 03/Oct/2007

Abstract:

A mouth cleaning device includes a head portion provided with bristles and an electrode

and a grip portion provided with an electrode. Further, the mouth cleaning device includes a boosting circuit for boosting an output voltage of a battery serving as a power source and applying the boosted voltage to the electrodes of the head portion and the grip portion

and a current limit circuit for limiting a current flowing from one electrode to the other via a human body.

Priority: JP20060275681 Applic. Date: 2006-10-06

Inventor: TANIGUCHI SHINICHI [JP]; KISHIMOTO SUEHISA [JP]; KUNITA TOMOHIRO [JP]; SHIMIZU HIROAKI [JP]; TAKAHASHI ATSUSHI [JP]; NAGAYAMA MASAYOSHI [JP]; HANATO YUMI [JP]; SANEMATSU WATARU [JP]; MASUDA YUKIHIRO [JP]

Title: Vacuum cleaning device

Applicant/Assignee: ALFRED KAERCHER GMBH & CO. KG

Application No.: 11/973874   Filing Date: 09/Oct/2007

Abstract:

The invention relates to a vacuum cleaning device comprising a dirt collection container which has a suction inlet and is in flow connection with at least one suction unit via at least one filter and at least one suction line, and comprising at least one external air inlet which opens into the suction line downstream of the at least one filter and is adapted to be closed by means of at least one closing valve, the closing valve having a movable valve body which, in a closed position, bears against at least one valve seat so as to form one or more sealing lines, the at least one sealing line delimiting an area which, in the closed position of the closing valve, is acted upon by a differential pressure. In order to develop the vacuum cleaning device in such a way that the at least one closing valve is of structurally simple design and the at least one filter can be completely cleaned within a short period of time, the invention proposes that the square of the total length of all sealing lines is at least 25 times the total size of all areas which are delimited by the sealing lines and acted upon by a differential pressure.

Priority: DE200510017568 Applic. Date: 2005-04-11; WO2006EP00672 Applic. Date: 2006-01-26

Inventor: STEWEN CHRISTIAN [DE]; HAEUSSERMANN ULI [DE]

Title: Metered dose inhaler

Applicant/Assignee:

Application No.: 11/546224   Filing Date: 11/Oct/2006

Abstract:

There is disclosed a metered dose inhaler for administering medication. In an embodiment, the metered dose inhaler includes a housing, a medication canister, a mouth-piece, an extension forming a chamber within the housing, and a one-way valve. In one embodiment, the metered dose inhaler includes a flange disposed on the mouth-piece. In another embodiment, the metered dose inhaler includes a peripheral edge configured to reduce spray away from the mouth-piece. In an embodiment, the metered dose inhaler includes a telescoping articulation between first and second ends of the housing. In another embodiment, the metered dose inhaler includes a telescoping extension. Other embodiments are also disclosed.

Priority:

Inventor: TIECK CATHARINE LAUREEN JOHNSO [US]; JOHNSON KENNETH WILLIAM [US]

Title: Patient Check System

Applicant/Assignee: SAGE PRODUCTS, INC

Application No.: 11/928816   Filing Date: 30/Oct/2007

Abstract:

A system for assisting in communication of the state of a patient's condition is disclosed. In an embodiment, a plastic container of washcloths includes two labels. The first label is mounted on the container and occludes an entry into the container. The second label also is mounted on the container via attachment to the first label. The second label includes a template that is mounted face down. In operation, the second label may be removed and observations regarding the patient's skin condition that are made during use of the washcloth can be marked on the template provided on the second label. The second label then may be communicated from one care provider to another care provider.

Priority: US2005-170995 Applic. Date: 2005-06-29

Inventor: CHAPPUIS RON [US]; HANIFL PAUL [US]; LAYER JAMES [US]

Title: LACTEAL COATED PIZZAS

Applicant/Assignee: BODY STRUCTURES, INC

Application No.: 11/309851   Filing Date: 13/Oct/2006

Abstract:

From dietary health to product diversity, Lacteal Coated Pizzas outperform the venerable four-hundred year old ethnic (Italian) pizzas. Lacteal Coated Pizzas are comprised of soft leaven dough/sourdough that is topped with a delicious, nutritious Lacteal Batter, and a conventional topping. The present invention's Lacteal Batters are innovative, heat-stable, hydrocolloidal-proteineous mixtures that possess unique performance-enhancing, rheological properties.

Priority:

Inventor: GRIGG LOUISE J [US]; JONSAN JOHN [US]

Title: Arrangement For Forming A Hole In A Jaw Bone, And Implant For Application In Said Hole

Applicant/Assignee:

Application No.: 11/587876   Filing Date: 26/Sep/2007

Abstract:

An arrangement for application or anchoring of an implant ( 17 ) in a jaw bone ( 8 ) by means of a hole formed in the jaw bone comprises a manually driven or machine-driven part which cooperates with the hole wall and which is designed to work with a hole wall cleaning function in order to form a surgically clean cut in the jaw bone. The implant can be arranged to be applied in the hole formed, and the implant is provided with one or more threads or thread parts which, when the implant is in the applied position, can be located opposite the cortical area or areas in the jaw bone. The implant is threads at the part or parts located opposite the spongy area or areas ( 11 ) of the jaw bone. By means of the invention, a surgically clean cut is obtained which, together with the design of the implant, contributes to accelerated osseointegration.

Priority: SE20040001096 Applic. Date: 2004-04-29; WO2005SE00294 Applic. Date: 2005-03-02

Inventor: BRAJNOVIC IZIDOR [SE]

Title: Nucleoside compounds and their use for treating cancer and diseases associated with somatic mutations

Applicant/Assignee: PTC THERAPEUTICS, INC

Application No.: 11/906665   Filing Date: 02/Oct/2007

Abstract:

The invention encompasses nucleoside compounds, compositions comprising the compounds and methods for treating or preventing diseases associated with nonsense mutations of mRNA by administering these compounds or compositions.

Priority: US2003-625059 Applic. Date: 2003-07-22; US20020398334P Applic. Date: 2002-07-24

Inventor: WILDE RICHARD G [US]; KENNEDY PAUL D [US]; ALMSTEAD NEIL G [US]; WELCH ELLEN M [US]; TAKASUGI JAMES J [US]; FRIESEN WESTLEY J [US]

Title: THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS

Applicant/Assignee: SCHERING CORP PHARMACOPEIA DRUG DISCOVERY, INC

Application No.: 11/861870   Filing Date: 26/Sep/2007

Abstract:

Disclosed are novel compounds of the formula: and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and ischemia reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of formula IA.

Priority: US2004-013753 Applic. Date: 2004-12-16; US20030531311P Applic. Date: 2003-12-19; US20030531713P Applic. Date: 2003-12-22

Inventor: BIJU PURAKKATTLE J [US]; TAVERAS ARTHUR G [US]; MERRITT J R [US]; BALDWIN JOHN J [US]; YU YOUNONG [US]; ZHENG JUNYING [US]; CHAO JIANHUA [US]; AKI CYNTHIA J [US]; FINE JAY [US]; LUNDELL DANIEL [US]; PRIESTLEY TONY [US]; REGGIANI ANGELO [IT]

Title: METHODS OF ENHANCING MUCOSAL HYDRATION AND MUCOSAL CLEARANCE BY TREATMENT WITH SODIUM CHANNEL BLOCKERS AND OSMOLYTES

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 11/851803   Filing Date: 07/Sep/2007

Abstract:

The present invention relates to methods and compositions for treating diseases ameliorated by increased mucociliary clearance and mucosal hydration by administering an effective amount of a sodium channel blocker as defined herein and an osmolyte to a subject to a subject in need of increased mucociliary clearance and mucosal hydration.

Priority: US20060845171P Applic. Date: 2006-09-18; US20060842669P Applic. Date: 2006-09-07

Inventor: JOHNSON MICHAEL R [US]; BOUCHER RICHARD C [US]; HIRSH ANDREW J [US]

Title: Haloalkyl-substituted pyrimidinone derivatives

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 11/895266   Filing Date: 22/Aug/2007

Abstract:

Haloalkyl-substituted pyrimidinone derivatives are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20060823261P Applic. Date: 2006-08-23

Inventor: BLUM CHARLES A [US]; ZHENG XIAOZHANG [US]; MARTINEZ ISAMIR [US]; CHENARD BERTRAND L [US]

Title: METHYLENE BLUE

Applicant/Assignee: STRAUMANN HOLDING AG

Application No.: 11/872234   Filing Date: 15/Oct/2007

Abstract:

Composition comprising a polymerizable compound with at least one conjugated unsaturated group and methylene blue to prevent premature polymerization of the polymerizable compound. The methylene blue is present in a concentration of 10 to 5000 ppm.

Priority: EP20050020181 Applic. Date: 2005-09-16; EP20040014072 Applic. Date: 2004-06-16; US2006-521971 Applic. Date: 2006-09-15; US2006-629567 Applic. Date: 2006-12-14; WO2005EP04977 Applic. Date: 2005-05-09

Inventor: MOLENBERG AALDERT [CH]

Title: Compositions and methods for affecting movement of contaminants, bodily fluids or other entities, and/or affecting other physiological conditions

Applicant/Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY

Application No.: 11/796132   Filing Date: 25/Apr/2007

Abstract:

Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the formulation may be applied to repair an injury or during surgery of the lung, eye or dura, or following an epidural or spinal tap, to stop leakage of blood, interstitial fluid, or cerebrospinal fluid. The formulation may be administered to a burn or ulcer. The formulation may be dispersed in a suture or adhesive for administration at the time of or as released following suturing or gluing of a wound, thereby limiting bleeding, loss of tissue fluids, or other fluids such as those produced by parenchymal tissues such as the liver, pancreas, and gastrointestinal tract. The formulation may be applied to any site of bleeding, in a bandage, gauze, sponge, or other material, for immediate control of bleeding, or released later to control bleeding if the initial treatment such as suturing or pressure is insufficient. In one embodiment, the formulation is provided as a dry or lyophilized powder. In another embodiment, the material is provided in water. In another embodiment, the material is provided in combination with an oil and forms a laminate. In another embodiment, the formulation is provided as a coating on a device, for example a stent or a catheter. The material is also useful to isolate tissue, for preservation of tissue for subsequent transplantation or reattachment, and as a bulking, stabilizing or hydrating agent.

Priority: US20060745601P Applic. Date: 2006-04-25

Inventor: ELLIS-BEHNKE RUTLEDGE [US]; LIANG YU-XIANG [CN]; SCHNEIDER GERALD E [US]; SO KWOK-FAI [CN]; TAY DAVID [CN]

Title: MOTORIZED FLOSSER AND METHOD OF USE

Applicant/Assignee: THE WILLIAM GETGEY COMPANY, INC

Application No.: 11/961128   Filing Date: 20/Dec/2007

Abstract:

A motorized flosser comprising an elongated body and a flossing head secured to an end portion of the elongated body. The flossing head oscillates in an arcuate manner. A battery powered motor drives a drive mechanism which reciprocates an output drive shaft, which drive shaft is in turn connected through a flexible drive rod to a drive disc. The drive disc oscillates in a rotary arcuate motion to impart either pure rotary arcuate oscillatory motion or a combined rotary arcuate motion and translatory motion to flossing material carried by a yoke of the flossing head. The flossing head may incorporate a toothpaste holder mounted upon the flossing head or toothbrush bristles mounted upon tines of the yoke of the flossing head.

Priority: US2005-224896 Applic. Date: 2005-09-13

Inventor: GETGEY WILLIAM F [US]; DYSON LEWIS R [US]; ANDRY CARL R [US]; FURNISH GREGORY R [US]

Title: CORROSION-RESISTANT BIMETALLIC TUBE AND ITS USE IN TUBE BUNDLE EQUIPMENT

Applicant/Assignee: SNAMPROGETTI S.P.A

Application No.: 11/761735   Filing Date: 12/Jun/2007

Abstract:

A bimetallic tube consisting of at least one tubular element in a first metal resistant to the corrosive and/or erosive action of a process fluid with which it is put in contact, having at least one end, or an area close to an end, externally coated with a layer of a second metal, different from the first and more suitable, with respect to this, for being seal-welded to a support. Tube bundle equipment to be used for thermal exchange operations at high temperatures and pressures, under conditions of high aggressiveness of the process fluids, wherein the tube bundle comprises at least one tube having the above characteristics. Said equipment is particularly used as a heat exchanger and decomposer, for example as a stripper, in the cycle of urea synthesis processes where there are conditions of high pressure, high temperatures, high aggressiveness of the process fluids, and in which the tube bundle consists of at least one tube having the above characteristics.

Priority: IT2006MI01223 Applic. Date: 2006-06-26

Inventor: GIANAZZA ALESSANDRO [IT]; MAIRANO LUCA [IT]; MERELLI GIUSEPPE [IT]; SANFILIPPO DOMENICO [IT]

Title: Blackberry Extract

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 11/629753   Filing Date: 16/Jun/2005

Abstract:

The invention concerns a blackberry leaf extract and its uses, in particular to slow down skin ageing, to treat the oral and pharyngeal cavity, and there in particular to prevent and slow down periodontitis and the excessive degradation of the periodontal connective tissue as well as damage to the teeth caused by matrix metalloproteinases

Priority: US20040581307P Applic. Date: 2004-06-18; US20050654380P Applic. Date: 2005-02-18; WO2005EP52793 Applic. Date: 2005-06-16

Inventor: HERRMANN MARTINA [DE]; JOPPE HOLGER [DE]; FRANKE HELGE [DE]; VIELHABER GABRIELE [DE]

Title: METHODS OF BLEACHING TEETH USING ADHESIVE DENTAL BLEACHING COMPOSITIONS CONTAINING POLYVINYLPYRROLIDONE

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/924014   Filing Date: 25/Oct/2007

Abstract:

A dental bleaching composition comprises a dental bleaching agent and a polyvinylpyrrolidone thickening agent. The bleaching composition may include water, flavoring agents, a basic substance and desensitizing agents, as desired. Polyvinylpyrrolidone avoids acid etching and chelation of teeth that were problematic in bleaches using carbomer as a thickener. A delivery system for delivering the bleaching composition comprises the aforementioned dental bleaching composition in combination with a moisture-resistant barrier layer such as a dental tray or a flexible strip of material.

Priority: US2004-870293 Applic. Date: 2004-06-17; US2003-715003 Applic. Date: 2003-11-17; US2002-288239 Applic. Date: 2002-11-05; US2001-770489 Applic. Date: 2001-01-27

Inventor: CHEN TIANMING [CN]

Title: Composition and Methods for Promoting Wound Healing and tissue Regeneration

Applicant/Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT CHARLESTON

Application No.: 11/721529   Filing Date: 20/Dec/2005

Abstract:

Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.

Priority: US20040638366P Applic. Date: 2004-12-21; US20050671796P Applic. Date: 2005-04-15; WO2005US46442 Applic. Date: 2005-12-20

Inventor: GOURDIE ROBERT [US]; GHATNEKAR GAUTAM [US]; JOURDAN JANE [US]

Title: Peptide sustained release compositions and uses thereof

Applicant/Assignee: AMGEN INC

Application No.: 11/411464   Filing Date: 25/Apr/2006

Abstract:

Sustained delivery compositions that modulate the release of incorporated prophylactic, therapeutic, and/or diagnostic agents, and methods of preparation and use thereof, are disclosed. In particular embodiments, the compositions include a polymeric matrix

a prophylactic, therapeutic, and/or diagnostic agent dispersed and/or dissolved within the polymeric matrix

and a carbohydrate component that is separately dispersed within the polymeric matrix. The carbohydrate component modulates the release of the incorporated agent from the polymeric matrix. The compositions can be prepared by dissolving a biocompatible polymer in a solvent to form a polymer solution, and separately dispersing a carbohydrate and a prophylactic, therapeutic, and/or diagnostic agent within the polymer solution. The polymer solution is then solidified to form a polymeric matrix, wherein a significant amount of the carbohydrates is dispersed in the polymeric matrix separately from the incorporated agent. In particular embodiments, the compositions include a polymeric matrix and a B1 peptide antagonist dispersed within the polymeric matrix.

Priority: US20050674872P Applic. Date: 2005-04-25

Inventor: WU CINDY W [US]; BURKE PAUL [US]; GOLDENBERG MERRILL S [US]; SHAN DAXIAN [US]

Title: Oxime Ester Photoinitiators

Applicant/Assignee: CIBA SPECIALTY CHEMICALS CORP

Application No.: 11/660346   Filing Date: 08/Aug/2005

Abstract:

Compounds of the formula (I), wherein R1, R2 and R10 independently of one another are C1-C20alkyl, phenyl, C1-C12alkylphenyl or phenyl-C1-C6alkyl

R3 and R4 independently of one another are hydrogen, C1-C20alkyl, NR6R7 or SR8, provided that at least one of R3 or R4 is NR6R7 or SR8

R5 is hydrogen or C1-C20alkyl

R6 and R7 independently of one another are C1-C20alkyl, or R6 and R7 together with the N-atom to which they are attached form a 5 or 6 membered ring, which optionally is interrupted by O, S or NR9 and which optionally additionally is substituted by one or more C1-C4alkyl

R8 is phenyl, biphenylyl, naphthyl, anthryl or phenanthryl, all of which optionally are substituted by one or more C1-C4alkyl

and R9 is hydrogen, C1-C20alkyl, C2-C4hydroxyalkyl or phenyl

exhibit an unexpectedly good performance in photopolymerization reactions.

Priority: EP20040103962 Applic. Date: 2004-08-18; WO2005EP53894 Applic. Date: 2005-08-08

Inventor: TANABE JUNICHI [JP]; KUNIMOTO KAZUHIKO [JP]; KURA HISATOSHI [JP]; OKA HIDETAKA [JP]; OHWA MASAKI [JP]

Title: DENTAL ARTICLES, METHODS, AND KITS INCLUDING A COMPRESSIBLE MATERIAL

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/551823   Filing Date: 23/Oct/2006

Abstract:

The present invention provides dental articles, kits, and methods including a compressible material. The compressible material optionally includes a hardenable dental composition (e.g., an adhesive or primer) that can be useful for bonding the dental article (e.g., an orthodontic appliance) to a tooth structure. Removal of excess hardenable and/or hardened dental composition, if desired, can be facilitated for embodiments in which the hardenable dental composition is an unfilled or lightly filled composition.

Priority:

Inventor: CINADER DAVID K [US]

Title: Pneumatic dental care device

Applicant/Assignee:

Application No.: 11/520334   Filing Date: 13/Sep/2006

Abstract:

A pneumatic dental care device for in-home use that is particularly suited for cleaning and providing prophylaxis of teeth, gingiva, and other oral tissue wherein pressurized air is directed into a user's oral cavity to clean teeth, remove oral debris and to both stimulate and massage gum line tissue. The compressed air, by means of a length of flexible tube, is delivered from a pressurized air source to a hand piece having both a nozzle tip and only one hand piece conduit. A control button disposed on the hand piece operably opens and closes a valve located within the hand piece, thereby allowing or stopping the outflow of compressed air from the nozzle tip of the hand piece. Additionally, a method of installing such a pneumatic dental care device for in-home use is disclosed.

Priority:

Inventor: CAIN JOAN CHINIQUY [US]; PETERS DENNIS EUGENE [US]

Title: Composition for Cleaning Dental Instruments and Process

Applicant/Assignee: VOCO GMBH

Application No.: 11/866884   Filing Date: 03/Oct/2007

Abstract:

A composition for cleaning dental instruments, comprising or consisting of: (a) one or more amino acids and/or salts thereof (aminocarboxylates) in a total amount of from 20 to 70 parts by weight, preferably 27.5 to 70 parts by weight, (b) one or more alpha-hydroxy acids and/or salts thereof in a total amount of from 15 to 45 parts by weight, (c) one or more alkali metal carbonates and/or bicarbonates in a total amount of from 0 to 50 parts by weight, (d) one or more surfactants in a total amount of from 0 to 5 parts by weight, (e) one or more tabletting auxiliaries in a total amount of from 0 to 10 parts by weight, (f) one or more corrosion inhibitors in a total amount of from 0 to 5 parts by weight, and (g) one or more other additives in a total amount of from 0 to 55 parts by weight, wherein components (a), (b), (c), (d), (e), (f) and (g)

are present in total in an amount of 100 parts by weight, and wherein the components are chosen such that the pH of a solution prepared by mixing the composition with 4,000 parts by weight of water is in the range of from 7.0 to 9.5.

Priority: EP20060125777 Applic. Date: 2006-12-11; CA20062570970 Applic. Date: 2006-12-11; WO2006EP62315 Applic. Date: 2006-05-15

Inventor: BARG ANDREE [DE]; PLAUMANN MANFRED T [DE]

Title: Cyclic Amide & Ester Pyrazinoylganidine Sodium Channel Blockers

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 11/573693   Filing Date: 18/Aug/2005

Abstract:

The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.

Priority: US20040602312P Applic. Date: 2004-08-18; WO2005US29345 Applic. Date: 2005-08-18

Inventor: JOHNSON MICHAEL R [US]

Title: Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

Applicant/Assignee: RENOVIS, INC

Application No.: 11/895293   Filing Date: 23/Aug/2007

Abstract:

Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Priority: US2006-375692 Applic. Date: 2006-03-14; US20050661531P Applic. Date: 2005-03-14

Inventor: KELLY MICHAEL G [US]; KINCAID JOHN [US]; JANAGANI SATYANARAYANA [US]; DUNCTON MATTHEW [US]

Title: Material forming a dental coping in the prepartion of a dental restoration

Applicant/Assignee:

Application No.: 11/586081   Filing Date: 26/Oct/2006

Abstract:

A material composition for use in forming a porous metal structure and dental coping in the preparation of a dental restoration comprising a composite of metal particles in a matrix including low fusing temperature metal particles and at least between 35 to 85% medium fusing temperature metal particles by volume with the medium fusing temperature metal particles possessing a melting characteristic which during heat treatment of the material composition to form the porous metal structure results in partial melting of the medium fusing temperature metal particles to the extent of between about 4% to 50% by volume of the particle mass of each medium fusing temperature metal particle.

Priority:

Inventor: SHOHER ITZHAK [IL]; WHITEMAN AHARON [IL]

Title: Funnel Having Stabilizing Weight

Applicant/Assignee:

Application No.: 11/553295   Filing Date: 26/Oct/2006

Abstract:

A weight for supporting a funnel in an upstanding orientation, the weight comprising a periphery defining an internal void, the void receiving the neck of the funnel, and also having a filler housed within the periphery, the filler providing mass to the weight. Other embodiments include a funnel with a weight incorporated therein, and a funnel system comprising a funnel, a removable weight and indicator means operatively coupled with the funnel.

Priority:

Inventor: FERGUSON JOE [US]

Title: Low-cost magnetically aided apparatus for separating dental amalgam from waste water

Applicant/Assignee:

Application No.: 11/586802   Filing Date: 25/Oct/2006

Abstract:

A replaceable module for capturing amalgam and mercury from the waste water disposal system of a dental office, in which the waste water flows into a settling chamber, overflows from the settling chamber into a magnetically-assisted sluice, and then after being further cleaned by the sluice, flows on to a sewer connection.

Priority:

Inventor: PLATH DAVID C [US]

Title: ANTIMICROBIAL FLAVOR AND ORAL CARE COMPOSITON CONTAINING THE SAME

Applicant/Assignee: TAKASAGO INTERNATIONAL CORPORATION

Application No.: 11/947549   Filing Date: 29/Nov/2007

Abstract:

The present invention provides antimicrobial flavors and flavor compositions which are of high safety and little influential on intestinal bacteria, as well as oral care compositions and foods containing the same. The flavor is selected from dihydrofarnesol, isocamphylcyclohexanol, levosandol, bacdanol, Santalinol, methyl atrarate, 10-undecen-1-ol, 2-methyl undecanal, sandalol, dodecanal, brahmanol, neroridol, o-methoxycinnamic aldehyde, methyl sandeflor, 9-decen-1-ol, 3-dodecenal, etc.

Priority: JP20010062916 Applic. Date: 2001-03-07; US2003-424774 Applic. Date: 2003-04-29; US2002-090642 Applic. Date: 2002-03-06

Inventor: HANADA MINORU [JP]; ARAI HARUO [JP]

Title: Pharmaceutical Compositon Containing Botulinum Neurotoxin A2

Applicant/Assignee:

Application No.: 11/659449   Filing Date: 03/Aug/2005

Abstract:

A composition, medicament or use, comprising or consisting of botulinum toxin type A2 and a surfactant, having one or more or all of the characteristics selected from the group consisting of

(a) a much longer duration of action

(b) a much faster rate of onset of muscular paralysis

(c) a significantly greater intramuscular safety margin

(d) a selective action on inhibition of smooth muscle contraction

(e) a selective action on inhibition of pain-related (nociceptive) nerve cell function: Wherein each characteristic is determined comparative to the same characteristic effect of botulinum toxin type A1.

Priority: GB20040017367 Applic. Date: 2004-08-04; GB20040021288 Applic. Date: 2004-09-24; GB20040021290 Applic. Date: 2004-09-24; GB20040023950 Applic. Date: 2004-10-28; GB20040023953 Applic. Date: 2004-10-28; WO2005GB03057 Applic. Date: 2005-08-03

Inventor: PANJWANI NAVEED [GB]; WEBB PAUL [GB]; PICKETT ANDY [GB]

Title: Methods And Compositions For Decreasing Saliva Production

Applicant/Assignee: NEUROHEALING PHARMACEUTICALS, INC

Application No.: 11/795210   Filing Date: 19/Jan/2006

Abstract:

The invention provides methods and compositions comprising an anti-cholinergic agent for decreasing saliva production and treating sialorrhea.

Priority: US20050645147P Applic. Date: 2005-01-19; WO2006US02206 Applic. Date: 2006-01-19

Inventor: MERELLO MARCELO [AR]; FARBER NEAL M [US]; RON EYAL S [US]

Title: Modified coagulation factor IX polypeptides and use thereof for treatment

Applicant/Assignee:

Application No.: 11/818985   Filing Date: 15/Jun/2007

Abstract:

Provided are modified factor IX (FIX) polypeptides and methods of generating modified FIX polypeptides. Also provided are pharmaceutical compositions, including compositions formulation for oral administration, that contain the modified FIX polypeptides, and methods of treatment using modified FIX polypeptides.

Priority: US20060815113P Applic. Date: 2006-06-19

Inventor: OYHENART JORGE [AR]; GALLET XAVIER [FR]; BORRELLY GILLES [FR]; GUYON THIERRY [FR]; VEGA MANUEL [FR]; DRITTANTI LILA [FR]

Title: POSTERIOR BITE RAMPS, KITS, AND METHODS OF USE TO CORRECT CLASS II AND/OR CLASS III MALOCCLUSIONS

Applicant/Assignee:

Application No.: 11/553909   Filing Date: 27/Oct/2006

Abstract:

A posterior bite ramp includes a tooth-attachment element and ramp element connected to the tooth-attachment element by a connection web. The tooth-attachment element is sized and configured for bonding to the lingual surface of a person's molar, behind the tooth, while the ramp element may be hingedly or bendably adjustable relative to the tooth-attachment element so as to form a ramp angle between the ramp element and an occlusal plane that is substantially perpendicular to the tooth-attachment element. The ramp element provides a ramp at a desired angle for engaging a corresponding molar of the opposite dental arch when the person's mouth is closed. The engagement between the ramp element and the corresponding molar of the opposite dental arch causes the lower jaw to move forward or backward relative to the upper jaw, thereby incrementally correcting a Class II or Class III malocclusion.

Priority:

Inventor: ABELS NORBERT [DE]; BACKES CLAUS H [DE]

Title: Novel Composition For Easing Human Childbirth

Applicant/Assignee: HCB HAPPY CHILD BIRTH HOLDING AG

Application No.: 11/718995   Filing Date: 10/Nov/2005

Abstract:

The present invention relates to a composition having a lubricant effect for use in particular during human vaginal delivery.

Priority: DE200410054552 Applic. Date: 2004-11-11; WO2005EP12058 Applic. Date: 2005-11-10

Inventor: SCHAUB ANDREAS F [CH]

Title: Total etch dental adhesive composition

Applicant/Assignee:

Application No.: 11/879671   Filing Date: 18/Jul/2007

Abstract:

Dental adhesive composition having a pH of at least 5, which comprises an aqueous solution containing (a) a polymerizable N-substituted alkyl acrylic or acrylic acid amide monomer

(b) a water-soluble polymerizable carboxylic acid

and (c) a water-soluble organic solvent.

Priority: US20060807636P Applic. Date: 2006-07-18

Inventor: KLEE JOACHIM E [DE]; LEHMANN UWE [DE]

Title: Dental composition with improved light stability

Applicant/Assignee:

Application No.: 12/002550   Filing Date: 18/Dec/2007

Abstract:

Dental composition having an improved light and thermal stability, including a mixture of at least a polymerizable resin, at least a polymerizable monomer, at least a polymerization initiator and/or a sensitizer and stabilizer, and at least an organic and/or inorganic filler and pigments in a content of 0 to 90 percent and at least one of the stable radicals.

Priority: US2003-452739 Applic. Date: 2003-06-02; US2001-754162 Applic. Date: 2001-01-04

Inventor: WALZ UWE [DE]; KLEE JOACHIM E [DE]

Title: Oral Care Toothbrush

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 11/932358   Filing Date: 31/Oct/2007

Abstract:

An oral care toothbrush includes a head mounted to one end of the handle containing a plurality of oral care elements. An oral care accessory is mounted to the opposite end of the handle. An oral care material dispenser is mounted in the head within the cleaning field defined by the oral care elements. The toothbrush is preferably made of small size and of lightweight so as to be readily portable for use away from the home.

Priority: US2004-843135 Applic. Date: 2004-05-11; WO2003US27455 Applic. Date: 2003-09-04; US20020408321P Applic. Date: 2002-09-05

Inventor: HOHLBEIN DOUGLAS J [US]; KEMP JAMES [US]; SORRENTINO ALAN V [US]; MINTEL THOMAS [US]

Title: Foldable Air Insulating Sleeve

Applicant/Assignee:

Application No.: 11/935181   Filing Date: 05/Nov/2007

Abstract:

A foldable air insulating sleeve for insulating beverage and food containers is herein provided. More particularly, the foldable air insulating sleeve secures a cup in a manner that leaves a pocket of air surrounding the cup. This provides for improved temperature regulation and sufficient thermal insulation to assist the user in firmly grasping and handling the cup despite excess heat or condensation caused by the temperature of the cup's contents. Because the bases of most disposable cups are narrower than their respective rims, more air and thus greater insulation is found towards the bottom of cups secured by foldable air insulating sleeves. The wider base also gives such cups more stability. Printable material can also be affixed on the foldable air insulating sleeve's outer surface for advertising or other purposes.

Some embodiments of the foldable air insulating sleeve include a lid to further improve thermal insulation.

Priority: US2003-459337 Applic. Date: 2003-06-11

Inventor: HECHMATI LAURENT [US]

Title: ISOLATION OF ANTIBODIES THAT CROSS-REACT AND NEUTRALIZE RANKL ORIGINATING FROM MULTIPLE SPECIES

Applicant/Assignee: ANAPTYS BIOSCIENCES, INC

Application No.: 11/863845   Filing Date: 28/Sep/2007

Abstract:

The invention provides specific binding members (e.g., antibodies or antigen-binding fragments thereof) which bind to RANKL originating from multiple species. An epitope recognized by the specific binding members can be selected from surface exposed loop domains that bind to and activate its cognate receptor, RANK (Receptor Activator of NFkB), on the surface of osteoclast precursors and other cell types. The invention provides peptides for generating such anti-RANKL antibodies, including murine sequences, other non-human sequences and cross-reactive peptides. The specific binding members are useful in the diagnosis and treatment of lytic bone diseases, including osteoporosis, rheumatoid arthritis, bone metastasis and hypercalcemia of malignancy, glucocorticoid-induced bone loss, a periodontal disease or condition, a cancer and Juvenile Paget's Disease. The binding members can also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or antigen-binding fragments thereof.

Priority: US2007-622928 Applic. Date: 2007-01-12; US20060758319P Applic. Date: 2006-01-12

Inventor: BOYLE WILLIAM J [US]

Title: METHOD FOR AMELIORATING PRURITUS

Applicant/Assignee:

Application No.: 11/848272   Filing Date: 31/Aug/2007

Abstract:

A method for preventing, treating, or ameliorating pruritus caused by skin, mucosa, or systemic disorder. The method comprises administering to a subject with pruritus or topically applying to an affected area with pruritus an effective amount of a formulation consisting essentially of a phenylbutyric acid or short-chain fatty acid derivative and a pharmaceutically acceptable carrier, salt or solvate thereof.

Priority: US2006-499936 Applic. Date: 2006-08-07; US2004-798119 Applic. Date: 2004-03-11; US2002-205738 Applic. Date: 2002-07-25

Inventor: CHUNG YIH-LIN [TW]; PUI NAM-MEW [TW]; CHANG WEI-WEI [US]

Title: POLYMERIZABLE ANTIMICROBIAL COMPOSITION

Applicant/Assignee: REGENTS OF THE UNIVERSITY OF COLORADO

Application No.: 11/774047   Filing Date: 06/Jul/2007

Abstract:

The present invention provides a polymerizable antimicrobial composition and a method for using the same. The polymerizable antimicrobial composition of the invention comprises an antimicrobial compound, a linker, and a polymerizable function group.

Priority: US20060806678P Applic. Date: 2006-07-06

Inventor: LAWSON MCKINLEY C [US]; ANSETH KRISTI S [US]

Title: DENTAL PROSTHESIS

Applicant/Assignee: ETKON CENTRUM FUR DENTALE CAD/CAM-TECHNOLOGIE AG

Application No.: 11/936222   Filing Date: 07/Nov/2007

Abstract:

The invention relates to a dental prosthesis identification means. The invention furthermore relates to a method and a device for manufacturing a dental prosthesis, whereby in this method and device, an identification means is formed or the formation of such an identification means is possible.

Priority: DE200610052478 Applic. Date: 2006-11-07

Inventor: HOLZNER STEPHAN [DE]; WEBER GERHARD [DE]

Title: METAL-RICH SILICEOUS COMPOSITIONS AND METHODS OF PRODUCING SAME

Applicant/Assignee:

Application No.: 11/557548   Filing Date: 08/Nov/2006

Abstract:

A modified sol-gel method to create metal-rich siliceous material, such as colloidal silica or aluminosilicate particles is disclosed. Initially, the metal salt of choice is added to a silicic acid solution or a silicic acid solution containing aluminum salt. The aluminum is added to vary the metal-support interaction as it forms Al-O-Si linkages within the silica matrix. Besides aluminum, other metals can be added that form M-O-Si (M=Ti, B, etc.) linkages, which do not become reduced when treated with a reducing agent. Once the metal, silicic acid and/or aluminum salt is generated, it is subjected to colloidal growth by addition to a basic heel. Upon colloidal synthesis, the metal salt containing colloidal particle is left as is to maximize colloidal stability or is reduced with hydrazine to produce the zero valence metal-containing colloidal particle. Keeping a particle colloidal before use may be an effective method of forming a catalyst material as it can be easily spray-dried or mixed with other materials for extruded catalyst particles.

Priority:

Inventor: HOLLAND BRIAN T [US]

Title: Angioplasty Balloon with Therapeutic/Aspiration Channel

Applicant/Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Application No.: 11/935131   Filing Date: 05/Nov/2007

Abstract:

An angioplasty balloon catheter with an added channel for delivering medication or removing body fluids distal to the site of angioplasty is disclosed. The balloons are especially useful in the treatment of occlusions in saphenous vein grafts, the coronary and carotid arteries, arteries arising from the aorta and branches thereof and in veins flowing to the heart or their tributaries and sub tributaries thereof.

Priority: US20060857082P Applic. Date: 2006-11-06

Inventor: GURM HITINDER [US]

Title: Personal care products and methods

Applicant/Assignee:

Application No.: 11/983287   Filing Date: 08/Nov/2007

Abstract:

In one embodiment, an oral-care system is provided. The oral-care system includes an electric toothbrush having a motor, a power source in electrical communication with the motor, and a bristle holder operatively connected to the motor. A display is in data communication with the electric toothbrush.

Priority: US20060859226P Applic. Date: 2006-11-15; US20070920698P Applic. Date: 2007-03-29

Inventor: FARRELL MARK E [US]; CHENVAINU ALEXANDER T [US]; ORTINS MARC P [US]; DENISHENKO VADIM [US]; DE CASTRO JOSE TADEO V [US]; TRAWINSKI PETER H R [DE]; HILSCHER ALEXANDER [DE]; SCHREMPEL BERT [DE]; STRATMANN MARTIN [DE]; SAGEL PAUL A [US]; BRAUN PHILLIP M [US]

Title: MULLION JOINT BETWEEN TWO FRAME MEMBERS OF A WINDOW OR DOOR FRAME

Applicant/Assignee: OMNIGLASS LTD

Application No.: 11/558531   Filing Date: 10/Nov/2006

Abstract:

A mullion for a window frame is formed by two frame members back to back to form the mullion. The facing surfaces are connected by providing aligned first and second recesses therein where each of the recesses has a mouth at the which is narrower than a base and has a connecting member along the aligned recesses with a portion of the connecting member within each recess as a loose fit. Each connecting member has associated with it an insert member with an insert portion between the outer surfaces of the first and second frame members forcing the outer surfaces apart to tighten the connecting member and a cover portion covering a junction between the side surfaces.

Priority: CA20062568062 Applic. Date: 2006-11-09

Inventor: DAVIES LAURENCE W [CA]

Title: NON-SILICA CONTAINING IMPRESSION AND CASTING MATERIALS

Applicant/Assignee:

Application No.: 12/014146   Filing Date: 15/Jan/2008

Abstract:

A chemical composition for use in preparing health related impressions, such as dental, medical, and prosthetic impressions is provided. The chemical composition may include a water-soluble alginate, an alginate insolubilizing cation-containing salt, a cation-release moderating component, and a cellulosic filler.

Priority: US2006-308885 Applic. Date: 2006-05-22

Inventor: RENN DONALD W [US]

Title: Dental Compositions with Sensitivity Relief

Applicant/Assignee: DISCUS DENTAL, LLC

Application No.: 11/927252   Filing Date: 29/Oct/2007

Abstract:

A one-component prescription fluoride treatment composition having both fluoride efficacy and sensitivity relief is disclosed. The composition includes at least one metal fluoride and a nerve desensitizing agent such as potassium nitrate. The invention further includes a composition having at least one metal fluoride less than about 1.15% by weight of at least one metal fluoride

less than about 5 percent by weight of at least one alkali metal salt having desensitizing effect

at least one carrier

and at least one foaming agent that has thickening property. The composition may be formulated into a gel, a paste or any other convenient form, some of which contain abrasives.

Priority: US2005-173632 Applic. Date: 2005-06-30; US20040585224P Applic. Date: 2004-07-02

Inventor: MACDONALD JEFF [US]; HAYMAN ROBERT [US]

Title: Protective Dental Balm and Method

Applicant/Assignee:

Application No.: 11/940318   Filing Date: 14/Nov/2007

Abstract:

A dental balm composition and method prevents damage to teeth which are prone to prolonged exposure to air or other drying conditions and which are therefore susceptible to tooth decay. The dental balm composition and uses an active decay preventing agent such as fluoride ion, xylitol or glycerin dispersed in a water insoluble adhesive and protective balm base such as petrolatum along with optional thickeners, flavorants and the like. The method of damage prevention applies the balm, such as by swab or finger, to the exposed surfaces of the subject's front teeth prior to vigorous physical activity, exercise, prolonged episodes of mouth breathing, or other harsh or deleterious conditions including drying conditions during strenuous periods of exercise or tooth whitening procedures.

Priority: US2005-113855 Applic. Date: 2005-04-25

Inventor: PERECHOCKY JOSEPH [US]

Title: SELF CONTAINED COMPOSITION ENHANCING DENTAL TRAY

Applicant/Assignee:

Application No.: 11/940492   Filing Date: 15/Nov/2007

Abstract:

The present invention relates to dental trays including a light source, a heat element or a combined light source and heating element that serves to enhance the treatment capacity of the composition. The dental tray is self-contained meaning that no external attachments that project from the mouth during use are required.

Priority: US20060865877P Applic. Date: 2006-11-15

Inventor: KHOURI LOUIE [US]

Title: Modulators of muscarinic receptors

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 11/894092   Filing Date: 20/Aug/2007

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US20060838701P Applic. Date: 2006-08-18

Inventor: DAVIES ROBERT J [US]; XU JINGWANG [US]

Title: Diphenylethylene compounds and uses thereof

Applicant/Assignee: CELGENE CORPORATION

Application No.: 11/983179   Filing Date: 07/Nov/2007

Abstract:

The present invention relates to Diphenylethylene Compounds and compositions comprising a Diphenylethylene Compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering to a subject in need thereof one or more Diphenylethylene Compounds. In particular, the invention relates to methods for preventing or treating cancer or an inflammatory disorder by administering to a subject in need thereof one or more Diphenylethylene Compounds. The present invention further relates to articles of manufacture and kits comprising one or more Diphenylethylene Compounds.

Priority: US2004-794931 Applic. Date: 2004-03-05; US20030452460P Applic. Date: 2003-03-05

Inventor: MULLER GEORGE W [US]; PAYVANDI FARIBOURZ [US]; ZHANG LING H [US]; ROBARGE MICHAEL J [US]; CHEN ROGER [US]; MAN HON-WAH [US]

Title: Multifunction health apparatus

Applicant/Assignee:

Application No.: 11/598128   Filing Date: 13/Nov/2006

Abstract:

The present invention provides a multifunction health device, which comprises a meter and a platform. The meter has two electrodes arranged separately at its two sides, and another electrode arranged in its bottom. The platform has four electrodes arranged in its top face, and a pressure sensor arranged in its inside. With or without some parts assisting, the single use of the meter can function as an ECG detector, a TENS machine, a thermometer, and a first sphygmomanometer. Connecting with the platform, the meter and the platform can function as an ECG detector, a weight scale, and a body composition estimator. Further, the meter can alternatively connect with a chassis thus functioning as a second sphygmomanometer, a stethoscope, a glucose meter, or a pulse oximeter.

Priority:

Inventor: TSO SHUN-WUN [TW]

Title: Method for producing immunoglobulins containing protection proteins and their use

Applicant/Assignee: THE REGENTS OF UNIVERSITY OF CALIFORNIA

Application No.: 11/605720   Filing Date: 28/Nov/2006

Abstract:

The immunoglobulins of the present invention are useful therapeutic immunoglobulins against mucosal pathogens such as S. mutans. The immunoglobulins contain a protection protein that protects the immunoglobulins in the mucosal environment. The invention also includes the greatly improved method of producing immunoglobulins in plants by producing the protection protein in the same cell as the other components of the immunoglobulins. The components of the immunoglobulin are assembled at a much improved efficiency. The method of the invention allows the assembly and high efficiency production of such complex molecules. The invention also contemplates the production of immunoglobulins containing protection proteins in a variety of cells, including plant cells, that can be selected for useful additional properties. The use of immunoglobulins containing protection proteins as therapeutic antibodies against mucosal and other pathogens is also contemplated.

Priority: US2004-781989 Applic. Date: 2004-02-18; US2000-717888 Applic. Date: 2000-11-20; US1999-312157 Applic. Date: 1999-05-14; US1995-434000 Applic. Date: 1995-05-04; US1994-367395 Applic. Date: 1994-12-30

Inventor: HIATT ANDREW C [US]; MA JULIAN K-C [GB]; LEHNER THOMAS [GB]

Title: CONTAINER MANAGEMENT SYSTEM

Applicant/Assignee: EGGS OVERNIGHT, INC

Application No.: 11/941366   Filing Date: 16/Nov/2007

Abstract:

Provided is a method for shipping a parcel from a primary to a secondary location in a reusable container, and returning the container to a tertiary location. The parcel is packaged in the container which includes a label construction. The label construction includes a base substrate for securing to the container, a sleeve overlaying the base substrate, and a transparent viewing window having an exposed surface for removably receiving an address label. A first removable label is adhered to the transparent viewing window and includes information corresponding to an address for the secondary location. A second removable label is placed inside the sleeve and includes information corresponding to an address for a tertiary location. The package is delivered to the secondary location where it is un-packed and the first label is removed thereby exposing the second label for viewing through the window for delivery to the tertiary location.

Priority: WO2005US09400 Applic. Date: 2005-03-18; US20040554559P Applic. Date: 2004-03-18

Inventor: DICKINSON KENT H [US]

Title: Endoscope cleaning/disinfecting apparatus

Applicant/Assignee: OLYMPUS MEDICAL SYSTEMS CORP

Application No.: 11/716249   Filing Date: 09/Mar/2007

Abstract:

An endoscope cleaning/disinfecting apparatus of the present invention includes a cleaning tub, a chemical solution tank for storing a germicide, a chemical solution collection pipe, a chemical solution pipe, a feed pipe, a germicide bottle tray which can be drawn from the body of the cleaning/disinfecting apparatus, and a control unit for performing control to prepare the germicide by mixing a basis, a buffering agent, and a diluent. The germicide bottle tray includes a storage part which stores at least a first bottle body out of the first bottle body for storing the basis or a second bottle body for storing the buffering agent, and a detection portion for outputting a detection signal in a state in which the bottle body is stored in the storage part. The control unit performs control based on the detection signal outputted from the detection portion to prepare the germicide.

Priority: WO2006JP323038 Applic. Date: 2006-11-17

Inventor: HASEGAWA HITOSHI [JP]; KOTANI KOJIRO [JP]

Title: Disinfectant bottle and endoscope cleaning and disinfecting apparatus

Applicant/Assignee: OLYMPUS MEDICAL SYSTEMS CORPORATION OLYMPUS MEDICAL SYSTEMS CORP

Application No.: 11/716408   Filing Date: 08/Mar/2007

Abstract:

An endoscope cleaning and disinfecting apparatus of the present invention includes: a bottle body, including, a rigid portion with a mouth portion, and a deformable portion which is in a first shape while the disinfectant being stored therein and is deformable from the first shape to a second shape upon being compressed when the disinfectant is discharged therefrom

and a disinfectant tray having a housing section which can be pulled out of the apparatus body and into which the bottle body is housed, the disinfectant tray being provided with a housing space for a first slide member which allows the housing section to slide relative to the apparatus body and a housing space for a second slide member which is slidable relative to the first slide member.

Priority: WO2006JP323037 Applic. Date: 2006-11-17

Inventor: KOTANI KOJIRO [JP]; HASEGAWA HITOSHI [JP]

Title: Novel Odorant Compounds, Synthesis Method, and Uses of Said Compounds

Applicant/Assignee: V. MANE FILS

Application No.: 11/795496   Filing Date: 13/Jan/2006

Abstract:

A compound of general formula (I) with or without the double bond illustrated by the dotted line. In formula (I), X is a CHO, CH2OH, CH2OC(O)R or CH(OR)2 group, and R represents a linear or branched C1-C5 alkyl or alkenyl chain. The synthesis method for the compound, and especially the 6,8-dimethyl-non-7-enal (1) prepared by the hydroformylation of the 5,7-dimethyl-octa-1,6-diene is also disclosed, as well as compositions containing the compounds of formula (I). Due to the odorant properties thereof, the compounds are highly useful in perfumery, especially for cosmetic products and household products.

Priority: FR20050000551 Applic. Date: 2005-01-19; WO2006FR00080 Applic. Date: 2006-01-13

Inventor: JAUNKY PIOTR [FR]; MANE JEAN [FR]; SCHROEDER MARTIN [GB]

Title: Lactobacillus paracasei-containing product

Applicant/Assignee: GENMONT BIOTECH INC

Application No.: 11/637711   Filing Date: 13/Dec/2006

Abstract:

A Lactobacillus paracasei-containing product used for inhibiting dental diseases caused by bacteria is provided, which comprises a plurality of Lactobacillus paracasei for inhibiting the growth of bacteria of dental diseases. Particularly, foods, oral hygiene products or oral treatment medicine containing the Lactobacillus paracasei when being administered or applied to a user can inhibit or reduce the number of pathogens of dental caries and periodontal diseases in oral cavity of the user, thereby achieving the efficacy of preventing dental diseases, such as dental caries and periodontal diseases.

Priority: TW20060129265 Applic. Date: 2006-08-09

Inventor: HSU CHING-HSIANG [TW]; CHEN YA-HUI [TW]; WANG YING-YU [TW]; LAI DING-YING [TW]; HSIEH FENG-CHING [TW]

Title: Dental Appliance Cleaners and Methods for Making and Using Them

Applicant/Assignee: CAO GROUP, INC

Application No.: 12/019493   Filing Date: 24/Jan/2008

Abstract:

The addition of the Iodide ion by way of iodide salts, such as sodium iodide and potassium iodide, to a peroxide such as hydrogen peroxide in a basic medium yields free radical oxygen and water

generating large amounts of heat and depleting the Hydrogen Peroxide in a matter of minutes. The free radical oxygen generated in this reaction can be utilized to oxidize organic molecules that produce offending stains on select items, including artificial teeth and other dental appliances. Once the free radical oxygen has oxidized the offending molecule the color is lost and the solubility changes allowing any loose fragments of the offending molecule to be washed away in the solvent. The iodide ion catalyzes the reaction allowing for precise control over the speed at which the stain is removed without the need for other expensive, cumbersome energy adding equipment such as lights, lasers, heat sources, etc.

Priority: US2004-922804 Applic. Date: 2004-08-20

Inventor: LARSEN ROBERT K [US]; OSTLER CALVIN D [US]

Title: TREATING MOUTH ULCER WITH LIVE BACTERIA

Applicant/Assignee: QINGDAO EAST SEA PHARMACEUTICALS, LTD

Application No.: 11/763072   Filing Date: 14/Jun/2007

Abstract:

This invention relates to using live beneficial bacteria for treating mouth ulcer.

Priority: CN20061138487 Applic. Date: 2006-11-17

Inventor: CUI YUNLONG [CN]

Title: Injectable microspheres for tissue construction

Applicant/Assignee: BIOSPHERE MEDICAL, INC

Application No.: 12/009181   Filing Date: 16/Jan/2008

Abstract:

The present invention relates to injectable compositions comprising biocompatible, hydrophilic, non-toxic and substantially spherical microspheres associated with stem cells useful for tissue construction and generation. The invention also relates to methods of tissue construction and generation, for the treatment of various tissue damage and defects, using the injectable compositions.

Priority: US2002-220984 Applic. Date: 2002-12-12; WO2001US08528 Applic. Date: 2001-03-15; US20000190542P Applic. Date: 2000-03-20

Inventor: VOGEL JEAN-MARIE [US]; BOSCHETTI EGISTO [FR]

Title: POLYMER COATED DRUG-ION EXCHANGE RESINS AND METHODS

Applicant/Assignee:

Application No.: 11/561723   Filing Date: 20/Nov/2006

Abstract:

Included are compositions, and methods of making, coated controlled-release drug and ion exchange resin form complexes. Methacrylate coatings, which can be free of plasticizers particularly with Eudragit(R) NE type polymer, are preferred to enhance the control of drug release from the drug-resin complexes. Liquid formulations including the coated resin forms and a chelating agent to inhibit degradation are also included.

Priority:

Inventor: LIU ZHI [US]; CHEN BEI [US]; GAO DANCHEN [US]; RAO MUKTI S [US]; USAYAPANT ARUNYA [US]

Title: Bactericidal Formulations

Applicant/Assignee:

Application No.: 11/719261   Filing Date: 15/Nov/2005

Abstract:

The invention relates to bactericidal formulations that come into contact with human body, particularly wash formulations including liquid soaps, comprising perfume ingredients active against gram-negative bacteria. Such compositions contact the target site, for example the skin surface, only for a short time, usually not longer than 30 seconds. Therefore the antibacterial action has to be of the bactericidal type and rapid. Furthermore, the bactericidal activity has to be sufficiently high to ensure an effect even when applied to wet substrates that will dilute the bactericidal formulation.

Priority: GB20040025305 Applic. Date: 2004-11-17; WO2005CH00676 Applic. Date: 2005-11-15

Inventor: NATSCH ANDREAS [CH]

Title: Moisture resistant pressure sensitive adhesives for orthodontic applications

Applicant/Assignee:

Application No.: 11/601106   Filing Date: 17/Nov/2006

Abstract:

A moisture resistant pressure sensitive adhesive for orthodontic application. Specifically, in accordance with one embodiment, a pressure sensitive adhesive (PSA) composition comprises a polymer base, and at least one bio-compatible hydrophobic tackifier. The PSA composition is structured such that the PSA composition is suitable for use in an oral environment.

Priority:

Inventor: SU LI-HUNG [US]

Title: Method for treating wounds to promote healing

Applicant/Assignee: MEDICAL NUTRITION USA, INC

Application No.: 11/985627   Filing Date: 16/Nov/2007

Abstract:

A method of treating a mammal to promote wound healing in the mammal in need thereof, comprising orally administering to the mammal an effective amount of a palatable, concentrated protein composition comprising an effective amount of hydrolyzed gelatin and tryptophan, and an ingestible carrier, the composition comprising the essential amino acids required by the mammal. Palatability is preferably achieved by the use of an effective amount of a sweetener. The method is particularly useful for treating wounds resulting from decubitus ulcers and bariatric surgery.

Priority: US2003-689236 Applic. Date: 2003-10-20; US20020422164P Applic. Date: 2002-10-29

Inventor: GANS ARNOLD M [US]

Title: Compounds for Nonsense Suppression, and Methods for Their Use

Applicant/Assignee:

Application No.: 11/577189   Filing Date: 13/Oct/2005

Abstract:

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

Priority: US20040617670P Applic. Date: 2004-10-13; US20040617633P Applic. Date: 2004-10-13; US20040617634P Applic. Date: 2004-10-13; US20040617655P Applic. Date: 2004-10-13; US20040617653P Applic. Date: 2004-10-13; US20040624170P Applic. Date: 2004-11-03; WO2005US36764 Applic. Date: 2005-10-13

Inventor: ALMSTEAD NEIL [US]; KARP GARY M [US]; WILDE RICHARD [US]; WELCH ELLEN [US]; REN HONGYU [US]

Title: Dust Mask

Applicant/Assignee: GOODY PRODUCTS, INC

Application No.: 11/563448   Filing Date: 27/Nov/2006

Abstract:

The invention is directed to a scented dust mask configured to provide a pleasant scent while being worn on the face of a user. The dust mask includes outer and inner layers of material shaped to cover the nose and mouth of the user, and connected to each other about the outer edges such that the layers of material define a pocket therebetween. The layers of material are configured to filter particulate matter from the air as the air passes through the material. The dust mask further includes a quantity of a scented material disposed and retained within the pocket defined by the inner and outer layers of material, with the scent of the scented material being detectable by the user when the dust mask is worn. The dust mask may further include a connection mechanism configured to retain the dust mask against the face of the user when the dust mask is worn.

Priority:

Inventor: SCHWARZ JEREMIAH [US]

Title: Sealing Condition of Multiple-Container, in Particular Double-Tube, Packages Designed for Instant Preparation

Applicant/Assignee: CEBAL SAS

Application No.: 11/915791   Filing Date: 22/May/2006

Abstract:

A double dispensing container including an outer container and an inner container, each container including a body and a head provided with a neck and a shoulder linking the neck to the body, the neck having a side wall and one or more dispensing orifices, the neck of the inner container being housed inside the neck of the outer container and having a section such that it provides one of more outflow passages for a pasty product A and, in combination with the inner surface of the outer container neck, one or more outflow passages for a pasty product B emerging onto a single or multiple orifice dispensing the product B. The inner neck is extended by a summit portion which is linked to the inner neck via a thin annular zone and which closes the single or multiple orifice dispensing product A.

Priority: FR20050005449 Applic. Date: 2005-05-30; WO2006FR01163 Applic. Date: 2006-05-22

Inventor: ZAKRZEWSKI HERVE [FR]; KERMAN ERIC [FR]

Title: Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with Porphyromonas gingivalis

Applicant/Assignee: THE UNIVERSITY OF MELBOURNE

Application No.: 11/731307   Filing Date: 30/Mar/2007

Abstract:

The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.

Priority: AU1997PO06528 Applic. Date: 1997-04-30; US2003-387977 Applic. Date: 2003-03-12; US2000-423056 Applic. Date: 2000-03-22; WO1998AU00311 Applic. Date: 1998-04-30

Inventor: REYNOLDS ERIC CHARLES [AU]; O'BRIEN-SIMPSON NEIL MARTIN [AU]; SLAKESKI NADA [AU]

Title: Methods and compositions for treatment of viral infections

Applicant/Assignee: CAVIT SCIENCES, INC

Application No.: 11/827491   Filing Date: 12/Jul/2007

Abstract:

A novel method of treating and preventing viral diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of viral infections and the diseases associated with such viral infections. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made compositions comprising a substance exhibiting Tubercin and/or SSM activity or a functional derivative thereof.

Priority: US2005-298629 Applic. Date: 2005-12-12

Inventor: KING COLM [US]

Title: Heteroaryl Substituted Piperazinyl-Pyridine Analogues

Applicant/Assignee:

Application No.: 11/795651   Filing Date: 19/Jan/2006

Abstract:

Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20050645496P Applic. Date: 2005-01-19; WO2006US02194 Applic. Date: 2006-01-19

Inventor: BLUM CHARLES A [US]

Title: Oral Compositions for Absorption of Phosphorus Compounds

Applicant/Assignee: CM&D PHARMA LIMITED

Application No.: 11/792047   Filing Date: 29/Nov/2005

Abstract:

The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates to pharmaceutical compositions to be administered by oral route in fasting periods, in order to absorb phosphorus compounds from fluids of the enteric tract, especially from saliva.

Priority: IT2004ME00015 Applic. Date: 2004-12-07; WO2005EP56289 Applic. Date: 2005-11-29

Inventor: SAVICA VINCENZO [IT]

Title: Aryl-Substituted Benzo[D]Isothiazol-3-Ylamine Analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 10/564263   Filing Date: 09/Jul/2004

Abstract:

Aryl-substituted benzo[d]isothiazol-3-ylamine analogues) are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20030485958P Applic. Date: 2003-07-10; WO2004US21914 Applic. Date: 2004-07-09

Inventor: BLUM CHARLES A [US]; ZHENG XIAOZHANG [US]

Title: 7-(ACRYLOYL) INDOLE COMPOSITIONS AND METHODS OF MAKING AND USING SAME

Applicant/Assignee: DECODE GENETICS, EHF

Application No.: 11/748897   Filing Date: 15/May/2007

Abstract:

The present invention is directed to pharmaceutical compositions of 7-(acryloyl)indoles, such as 4,5 -Dichloro-thiophene-2-sulfonic acid [(E)-3-[1-(2,4-dichlorophenylmethyl)-5-fluoro-3-methyl-1H-indol-7-yl]-acryloyl]amide (DTSI), having a structure shown below. The invention is also directed to methods of treatment utilizing formulations of the DTSI and processes of preparation of the formulations.

Priority: US20060800806P Applic. Date: 2006-05-16

Inventor: SINGH JASBIR [US]; DUAN MATT SHAOMING [US]; THORSTEINSSON THORSTEINN [US]; FRIEDMAN MITCHELL B [US]; GURNEY MARK [US]

Title: PROCESS FOR THE ADDITIVATION OF SYNTHETIC FIBRES, ARTIFICIAL FIBRES AND POLYMERS WITH SPECIAL PROPERTIES

Applicant/Assignee:

Application No.: 11/938337   Filing Date: 12/Nov/2007

Abstract:

A process for the additivation of synthetic fibres, artificial fibres and polymers conferring special properties to them, the process comprising the following steps: the encapsulation of an additive in the pores of a porous material

the incorporation of particles of the porous material (capsules) into the polymer matrix of the fibre

and spinning of the fibre

the capsule withstanding the temperatures and other conditions of the different manufacturing processes which the fibres might undergo and the introduction of the additive into the polymer matrix thereof, characterised in that the porous material is a metal oxide, a zeolite, an aluminophosphate, clay, a carbon material, a hybrid organic-inorganic material or a porous polymer. The invention is an improvement in the additivation process of fibres and polymers in terms of the nature of the capsules used, the increase in the storage capacity of additives thereof, the process of incorporating the capsules into the polymer matrix of the fibres and the fact that the present invention refers to an industrial process.

Priority: EP20060380293 Applic. Date: 2006-11-14

Inventor: LOPEZ MIGUEL ANGEL CABALLERO [US]; LASIERRA PATRICIA ZAGALAZ [US]; GUAJARDO SERGIO JOSE SEGURA [US]; CAMAS MARIA ELENA PIERA [US]; GARCIA EDUARDO PEREZ [US]; ARISO CARLOS TELLEZ [US]; CERESUELA JOAQUIN CORONAS [US]; RAMIRO JESUS SANTAMARIA [US]

Title: Methods of Whitening Teeth

Applicant/Assignee: BRITESMILE PROFESSIONAL, LLC

Application No.: 11/927636   Filing Date: 29/Oct/2007

Abstract:

The present invention relates to improved dental compositions and methods for bleaching teeth. More specifically, this invention is directed towards hydrogen peroxide-containing compounds that are maintained at a substantially constant pH range of 6.0-10.0 during the tooth-bleaching procedure in the presence of a calcium chelating agent.

Priority: US2005-256654 Applic. Date: 2005-10-21; US1998-192609 Applic. Date: 1998-11-16; US1996-719569 Applic. Date: 1996-09-25; US19950004258P Applic. Date: 1995-09-25

Inventor: MONTGOMERY R ERIC [US]

Title: Pharmaceutical Composition for Treatment of Tear and Salivary Fluid Drying

Applicant/Assignee: ASTELLAS PHARMA, INC

Application No.: 11/861725   Filing Date: 26/Sep/2007

Abstract:

[Problem] An agent for treating eye and mouth dryness, which does not accompanies undesirable actions is provided. [Means for Resolution] Administration of the compound A made it possible to accelerate tear and salivary fluid secretion without accompanying sweating and its sustained release administration enabled acceleration of lacrimal gland and salivary gland cell growth as well.

Priority: JP20040292611 Applic. Date: 2004-10-05; US2005-578682 Applic. Date: 2005-10-04; WO2005JP18310 Applic. Date: 2005-10-04

Inventor: OKADA YOHEI [JP]; IKEDA KEN [JP]; WANIBUCHI FUMIKAZU [JP]; YOSHIHARA KEIICHI [JP]; KONDO HIROMU [JP]; KOJIMA HIROYUKI [JP]

Title: SKIN PROTECTION COMPOSITION

Applicant/Assignee: HOUOUDOU CO., LTD

Application No.: 12/026383   Filing Date: 05/Feb/2008

Abstract:

The present invention provides a method comprising suppressing the growth of a microorganism selected from the group consisting of anthrax bacteria and a virus selected from the group consisting of herpes simplex virus and influenza virus by providing an object containing or impregnated with a composition comprising Sasa extract, and bringing the microorganism into contact with the composition.

Priority: US2005-246194 Applic. Date: 2005-10-11; WO2003JP04635 Applic. Date: 2003-04-11

Inventor: TSUCHIDA YUUZOU [JP]; TSUCHIDA KOTAROU [JP]; TSUCHIDA KENJIROU [JP]; WATANABE KUNITOMO [JP]; NAKAMURA YOSHIKO [JP]; IWASAWA ATSUO [JP]

Title: Direct press on veneer

Applicant/Assignee:

Application No.: 11/986636   Filing Date: 24/Nov/2007

Abstract:

A direct resin veneer ( 2 ) for creating a veneer on a tooth surface comprising a thin planar expanse of an uncured restorative material, or direct resin veneer ( 4 ). The veneer ( 4 ) has a generally tooth configuration that is generously sized to permit adequate coverage for any tooth. Adhered to at least one side of the restorative material is a flexible pliant non-sticky planar sheath ( 6 ). The sheath ( 6 ) material has a curved gingival arch contour ( 10 ) for gum line alignment and various tab-like protrusions that permit placement upon a tooth. An inferior peeling tab ( 12 ) allows for sheath to be separated from the resin veneer ( 4 ) subsequent to tooth surface placement. And the lateral grasping tabs ( 16 ) permit delivery to a tooth's surface.

Priority: US20060872464P Applic. Date: 2006-12-02

Inventor: VISCOMI BRIAN D [US]

Title: Novel Alkyl Substituted Homopiperazine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors

Applicant/Assignee:

Application No.: 11/795768   Filing Date: 09/Feb/2006

Abstract:

This invention relates to novel alkyl substituted homopiperazine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20050000197 Applic. Date: 2005-02-10; US20050651217P Applic. Date: 2005-02-10; WO2006EP50785 Applic. Date: 2006-02-09

Inventor: PETERS DAN [SE]; DAHL BJARNE H [DK]; OLSEN GUNNAR M [DK]; NIELSEN ELSEBET OSTERGAARD [DK]; SCHEEL-KRUGER JORGEN [DK]; REDROBE JOHN PAUL [DK]

Title: Thiazole and oxazole-substituted arylamides as P2X3 and P2X2/3 antagonists

Applicant/Assignee: ROCHE R&D CENTER CHINA, LTD ROCHE PALO ALTO LLC

Application No.: 11/983225   Filing Date: 08/Nov/2007

Abstract:

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R<1 >is a group of formula A or formula B, and X, R<2>, R<3>, R<4>, R<5>, R<6>, Rand Rare as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the subject compounds.

Priority: US20060858283P Applic. Date: 2006-11-09

Inventor: DILLON MICHAEL PATRICK [US]; HAWLEY RONALD CHARLES [US]; CHEN LI [CN]; FENG LICHUN [CN]; YANG MINMIN [CN]