Title: Smoking article with tobacco beads

Applicant/Assignee: PHILIP MORRIS USA INC

Application No.: 11/358027   Filing Date: 22/Feb/2006

Abstract:

A component of a smoking article having tobacco beads. The tobacco beads can be located in a filter and/or a tobacco rod. The filter can be a multi-component filter, wherein an sorbent (preferably upstream) removes at least one constituent from mainstream tobacco smoke passing through the filter and downstream tobacco beads compensates for taste lost to the sorbent. The tobacco beads optionally include flavorants in addition to tobacco particulates. The tobacco beads can be located within a cavity in the filter or within the tow. This component can comprise additional flavors, which are released into the mainstream smoke under ambient conditions. The tobacco beads optionally include binders such as microcrystalline cellulose or other cellulosic material, which can be formed into a paste with tobacco powder and optionally with additional flavors. The paste can be extruded and spheronized to form the tobacco beads.

Priority: US20050655431P Applic. Date: 2005-02-24

Inventor: ZHUANG SHUZHONG [US]; KARLES GEORGIOS D [US]; NEPOMUCENO JOSE [US]; JUPE RICHARD [US]; ASSMANN GERSON [US]; ZIMMERMANN STEPHEN [US]; LEWIS BENJAMIN [US]; SHERRON JAMES [US]; WILLIS VIVIAN E [US]

Title: Industrial tunnel type wood burning oven for the baking of pizza and similar alimentary products

Applicant/Assignee:

Application No.: 11/150302   Filing Date: 13/Jun/2005

Abstract:

An industrial oven with tunnel for the baking of pizza or similar alimentary products is shown, made up of a bearing structure ( 10 ) in refractory material comprising an inlet mouth ( 40 ) and one of outlet ( 41 ) connected by a passing through tunnel ( 4 ) along which a baking surface ( 5 ) supporting pizza or similar alimentary products slides. Said oven is heated with firewood and it comprises slits ( 22, 24 ) for the passage of primary air for the combustion of the firewood and air for the oxidation of the excess smoke, said primary and secondary air being moved by fans ( 50 ) controlled by a control unit which processes data on the composition of the air detected inside the oven by sensors ( 26 ), a top combustion chamber ( 15 ) housing top furnaces ( 17 ) made up of top grates ( 18 ) supporting combustible firewood and a bottom combustion chamber ( 16 ) housing bottom furnaces ( 30 ) made up of bottom grates ( 31 ) supporting combustible firewood.

Priority: IT2005MI00934 Applic. Date: 2005-05-23

Inventor: FERRO PIETRO [IT]

Title: Skin preparation for external use characterized by containing sugar derivative of alpha, alpha-trehalose

Applicant/Assignee:

Application No.: 10/545166   Filing Date: 11/Aug/2005

Abstract:

The present invention has an object to provide an external dermatological formulation having satisfactory blood flow-promoting effect, antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing effect, hair nourishing effect, emusifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and/or transdermal absorption-promoting effect with a satisfactory safety and skin feeling

The object is solved by providing an external dermatological formulation comprising a saccharide derivative of alpha,alpha-trehalose and one or more members selected from substances having any one of blood flow-promoting effect, antiinflammatory effect, antibacterial effect, moisturizing effect, whitening effect, UV-absorbing effect, UV-scattering effect, antioxidant effect, hair growing efect, hair nourishing effect, emulsifying effect, astringent effect, wrinkle-reducing effect, cell-activating effect and transdermal absorption-promoting effect.

Priority: JP20030035751 Applic. Date: 2003-02-13; JP20030305821 Applic. Date: 2003-08-29; WO2004JP01401 Applic. Date: 2004-02-10

Inventor: TANABE FUJIMI [JP]; KUBOTA MICHIO [JP]; TATSUKAWA HIROMI [JP]; FUKUDA SHIGERU [JP]; MIYAKE TOSHIO [JP]

Title: Morphine controlled release system

Applicant/Assignee: EGALET A/S

Application No.: 10/550453   Filing Date: 26/Mar/2004

Abstract:

A composition for controlled release of an opioid from a pharmaceutical composition, the method comprises controlling the release of at least one opioid into an aqueous medium by erosion of at least one surface of a pharmaceutical composition comprising I) a matrix composition comprising a) polymer or a mixture of polymers, b) an opioid and, optionally, c) one or more pharmaceutically acceptable excipients, and (i) a coating. The matrix composition has a conus-like shape so the surface area exposed to the aqueous medium increases at least during initial erosion of the matrix composition, and the dissolution of the opioid-when tested in a Dissolution Test as described herein with or without application of sinkers-results in a zero order release of at least 80% of the opioid contained in the composition. Such compositions are especially suitable for controlled release of an opioid to obtain a delayed pead concentration and a prolonged therapeutically effective plasma concentration upon oral administration. Once or twice daily administration is possible. The matrix typically comprises PEO and the active substance is typically an opioid such as morphine or a glucuronide thereof.

Priority: DK20030000463 Applic. Date: 2003-03-26; WO2004DK00215 Applic. Date: 2004-03-26

Inventor: FISCHER GINA [DK]; BAR-SHALOM DAMEL [DK]; SLOT LILLIAN [DK]; ANDERSEN CHRISTINE [DK]

Title: Liquid-filled chewing gum composition

Applicant/Assignee: CADBURY ADAMS USA, LLC CADBURY ADAMS USA LLC

Application No.: 11/408761   Filing Date: 21/Apr/2006

Abstract:

Some embodiments provide a chewing or bubble gum composition which includes a liquid fill composition and a gum region which includes a gum base surrounding the liquid fill which may include a modified release component, wherein the gum region includes a polyol composition including at least one polyol and having a water solubility of less than 72% by weight at 25 DEG C. The composition may also include a coating region which surrounds the gum region.

Priority: US2005-210954 Applic. Date: 2005-08-24; US2004-925822 Applic. Date: 2004-08-25; US20060776641P Applic. Date: 2006-02-24; US20050683634P Applic. Date: 2005-05-23; US20050650758P Applic. Date: 2005-02-07

Inventor: JANI BHARAT [US]; KABSE KISHOR [US]

Title: Tooth whitening apparatus and methods for whitening teeth using an intra-oral light generating device

Applicant/Assignee: NOVOCAL, LLC

Application No.: 11/174216   Filing Date: 01/Jul/2005

Abstract:

A tooth whitening apparatus and method using an intra-oral light generating device, whereas the light generating device is placed inside a patient's mouth and bucally to the jaws to produce a light source, comprises the steps of applying inside a means for depositing and applying, adapted for the upper and lower jaws, a tooth whitening agent comprising an optical chemical agent. Said means for depositing and applying are made of suitable material comprising plastic, and adapted inside the patient's mouth and adjacent to the inner surface of the patient's lips. The method further includes the steps of placing the means for depositing and applying filled with a light-activated, tooth whitening agent into the patient's mouth, onto the corresponding jaws and positioning the light generating device, inside the patient's mouth, bucally to the jaws, whereas the intra-oral light is located adjacent to surface of the means for depositing-and-applying, and on the inner surface of the cheeks and lips of the mouth of said patient. Therein the intra-oral light activates the tooth whitening agent for a period of time.

Priority:

Inventor: NGUYEN BAO L [US]; NGUYEN LIET H [US]

Title: Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use

Applicant/Assignee: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.I I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L

Application No.: 11/455501   Filing Date: 19/Jun/2006

Abstract:

The present invention refers to the use of extracts from selected and stabilised cell lines comprising phenylpropanoids with high anti-oxidant capacity having a verbascoside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%, in human and veterinary medicine, and for nutritional and cosmetic purposes.

Priority: EP20050425442 Applic. Date: 2005-06-20; EP20050425586 Applic. Date: 2005-08-08

Inventor: DAL MONTE RENZO [IT]; DAL TOSO ROBERTO [IT]; MINGHETTI ANACLETO [IT]; CRESPI PERELLINO NICOLETTA [IT]; PRESSI GIOVANNA [IT]

Title: Methods and compositions for treating Parkinson's disease

Applicant/Assignee: BODYBIO, INC

Application No.: 11/171308   Filing Date: 01/Jul/2005

Abstract:

The invention as disclosed herein provides pharmaneutical compositions and methods for treating, ameliorating, or preventing the symptoms of Parkinson's Disease. The pharmaneutical compositions of the invention contain in an effective amount a first and a second composition, the first composition comprises an effective amount of one or more phosphatidylcholine formulations and the second composition comprises an effective amount of one or more constituents comprising essential fatty acid supplements, trace minerals, butyrate, electrolytes, methylating agents, reduced glutathione, or a combination thereof, in a suitable carrier.

Priority:

Inventor: KANE PATRICIA [US]; KANE EDWARD [US]

Title: Compounds and methods for use in treating neoplasia and cancer based upon inhibitors of isoprenylcysteine methyltransferase

Applicant/Assignee: PURDUE RESEARCH FOUNDATION

Application No.: 10/552754   Filing Date: 26/Mar/2004

Abstract:

The present invention relates to a novel method for the treatment of neoplasia, including cancer and other diseases and conditions in humans and mammals. More particularly, in preferred aspects, the present invention provides a method for the use of prenylcysteine analogs for the treatment of neoplasia, hyperproliferative cell growth including psoriasis, restenosis following cardiovascular surgery, hyperplasia, including renal hyperplasia, chronic inflammatory diseases including rheumatoid and osteoarthritis, among others.

Priority: US20030457862P Applic. Date: 2003-03-26; WO2004US09506 Applic. Date: 2004-03-26

Inventor: GIBBS RICHARD A [US]; HENRIKSEN BRIAN S [US]; HRYCYNA CHRISTINE A [US]; ANDERSON JESSICA L [US]

Title: Dental cement composition containing composite particles with grafted polyacidic polymer chains

Applicant/Assignee: DENTSPLY DE TREY GMBH

Application No.: 11/217542   Filing Date: 01/Sep/2005

Abstract:

A dental cement composition comprising (i) a particulate reactive inorganic filler capable of leaching metal ions in the presence of an acid, and (ii) composite particles with grafted polyacidic polymer chains, which are obtainable by a process comprising the following steps: (a) polymerizing one or more free radically polymerizable monomers containing optionally protected acidic groups in the presence of (a1) an initiatior system comprising initiator particles displaying a moiety comprising a radically transferable atom or group as a polymerization initiation site

and (a2) a catalyst facilitating controlled/living polymerisation, and (a3) optionally further polymerizable monomers, for forming a composite particle with grafted optionally protected polyacidic polymer chains

and (b) optionally deprotecting protected acidic groups, for forming composite particles with grafted polyacidic polymer chains.

Priority: EP20040012495 Applic. Date: 2004-05-26; US20040606114P Applic. Date: 2004-09-01

Inventor: KLEE JOACHIM E [DE]; BRUGGER STEFAN [DE]; WEBER CHRISTOPH [DE]; MULLER AXEL H [DE]; MORI HIDEHARU [JP]

Title: Dragline bucket rigging and control apparatus

Applicant/Assignee: CMTE DEVELOPMENT LIMITED

Application No.: 11/521373   Filing Date: 15/Sep/2006

Abstract:

A large electric dragline having a house ( 35 ) and boom ( 37 ) is provided with spaced apart in-line sheaves ( 34 ) and ( 36 ) at boom point to separate hoist ropes ( 31 ) and ( 32 ) which are led to the front and rear of bucket ( 30 ) respectively. Differential hoist rope control allows accurate and continuous adjustment of the bucket carry angle during all modes of operation. Also described is a computer control system giving continuous accurate control of carry angle by differential hoist rope operation, with manual selection of mode of operation.

Priority: US2002-182023 Applic. Date: 2002-07-19; WO2000AU01336 Applic. Date: 2000-10-31; AU2000PR00067 Applic. Date: 2000-09-12; AU2000PQ07400 Applic. Date: 2000-05-10; AU2000PQ06348 Applic. Date: 2000-03-20; AU1999PQ03846 Applic. Date: 1999-11-03

Inventor: ROWLANDS JEFFREY C [AU]

Title: Shipping container

Applicant/Assignee:

Application No.: 11/520424   Filing Date: 12/Sep/2006

Abstract:

A container to receive a parcel for shipment to an intended recipient comprises a pouch having a pouch interior and a mouth, a closure movable between open and closed positions, and a protective insert structure removably disposed in the pouch interior to substantially envelop the parcel and reduce risk of damage to it during shipment.

Priority: US2002-170013 Applic. Date: 2002-06-10; US2001-956478 Applic. Date: 2001-09-18

Inventor: DICKINSON KENT H [US]

Title: Toothpaste compositions with reduced abrasivity

Applicant/Assignee:

Application No.: 10/544282   Filing Date: 04/Feb/2004

Abstract:

Toothpaste compositions are disclosed. The toothpaste composition comprises a binder

a surface active agent

an abrasive

a humectant

and water, in which: (1) the abrasive is silica, the composition additionally comprises a silica thickener, and the composition comprises 1 to 7 wt % of the silica thickener, less than 15 wt % of the silica abrasive, 45 to 70 wt % water, 0.8 to 3.0 wt % of a surface active agent

0.05 to 3.0 wt % the binder, or (2) the abrasive is silica, the composition additionally comprises a silica thickener, the composition comprises 2 to 22 wt % total silica, 0.8 to 3.0 wt % of a surface active agent

0.05 to 3.0 wt % the binder, and the composition additionally comprises about 0.1 to 8.0 wt % of non-colloidal microcrystalline cellulose, colloidal microcrystalline cellulose, or a mixture thereof

or (3) the binder is a calcium based abrasive, the binder is a cellulose gum, and the composition comprises 25 to 55 wt % of the calcium based abrasive, 35 to 60 wt % water, 0.8 to 3.0 wt % of the surface active agent, and 1.0 to 3.0 wt % of the binder.

Priority: US20030445376P Applic. Date: 2003-02-05; US20030479690P Applic. Date: 2003-06-19; WO2004US03242 Applic. Date: 2004-02-04

Inventor: GADKARI VIJAY K [IN]; RANDIVE VINAYAK B [IN]; VENKAT MAHALINGAM R [IN]; BETRABET NAMITA A [IN]; KADAM SITARAM A [IN]

Title: Dental gel etchants

Applicant/Assignee:

Application No.: 11/360980   Filing Date: 23/Feb/2006

Abstract:

Etching compositions, curable compositions, packaged products and methods of use for the treatment of bone substrate, i.e., teeth, are described. The etch compositions generally include a gelling agent, an inorganic acid, an organic acid and either a solvent, a surfactant or mixtures thereof. The curable composites include reactive monomers and crosslinking agents that are effective to adhere to the surface of the treated substrate. The methods of the invention provide the ability to modify a bone or bone-like surface so that the curable composition, such as an adhesive resin, can be used in combination with a restorative material.

Priority: US20050656271P Applic. Date: 2005-02-25

Inventor: KANCA JOHN A III [US]

Title: Dental template and method of visually demonstrating an overlay for a dental patient and setting the horizontal plane with an overlay

Applicant/Assignee:

Application No.: 11/226113   Filing Date: 14/Sep/2005

Abstract:

A dental prosthesis or template ( 10 ) simulates the front surfaces of a patient's teeth and is overlayed over a patient's natural teeth ( 40 ) to provide an indication of what a dental porcelain overlay may look like once applied to the patient's teeth. The dental template preferably is made from a flexible urethane or sanaprene material to allow the template to be applied against the person's natural teeth and temporarily adhere the template to his teeth provide for the visual demonstration of potential improvement to the patient's smile.

The dental template ( 10 ) can be adhered to a set gel or registration paste to set the facial plane ( 75 ) at which the overlay should lie relative to the tooth plane ( 73 ) of the natural teeth ( 40 ) to establish a final restoration with an ideal and naturally appearing aesthetic result as it relates to horizontal facial planes and facial appearances.

Priority: US2005-096602 Applic. Date: 2005-04-01

Inventor: STONISCH MARY S [US]

Title: Device having activated textured surfaces for treating oral tissue

Applicant/Assignee: BIOLASE TECHNOLOGY, INC

Application No.: 11/441788   Filing Date: 25/May/2006

Abstract:

Mouthpieces having activated textured surfaces that can be implemented using repetitive movement mechanisms and energy (e.g., electromagnetic radiation) emitting sources are disclosed. The mouthpieces may be used to provide detection, treatment and management of conditions including tooth discoloration and periodontal disease. Implementations can include a low-profile mouthpiece or a mouthpiece covering only front sides of the upper and lower teeth. Other combinations may include full-mouth implementations suitable for simultaneously covering part or all of a patient's upper and lower rows of teeth. The activated textured surfaces may include a surface topography consisting of bristles.

Priority: US20050684418P Applic. Date: 2005-05-25; US20050703962P Applic. Date: 2005-07-29; US20050739273P Applic. Date: 2005-11-23

Inventor: JONES JEFFREY W [US]; RIZOIU IOANA M [US]; BOUTOUSSOV DMITRI [US]

Title: Dental repair material

Applicant/Assignee:

Application No.: 11/473536   Filing Date: 23/Jun/2006

Abstract:

The invention is directed to an improved dental composition useful in the repair of cavities, apex repairs, root perforations and root canals. Disclosed is a dental composition and dental composition additive which have improved handling characteristics, for example improved viscosity and setting time. The addition of effective amounts of a modified cellulose and calcium chloride to available dental repair compounds, such as mineral trioxide compound, results in the improved dental composition without affecting the other characteristics of the dental repair compound.

Priority: US20050693268P Applic. Date: 2005-06-23

Inventor: HATTON JOHN F [US]; BER BENJAMIN S [US]; STEWART GREGORY P [US]

Title: Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia

Applicant/Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS

Application No.: 11/421960   Filing Date: 02/Jun/2006

Abstract:

Compositions and methods of treating or preventing hot flashes, night sweats, and/or insomnia in a subject that involve scopolamine are disclosed. For example, methods of treating hot flashes, night sweats, and/or insomnia in a subject that involve transdermal delivery of scopolamine are set forth herein.

Priority: US20050697718P Applic. Date: 2005-07-08

Inventor: MCKENZIE SHIRLYN B [US]

Title: Laser curable polymerisable composition for he protection of hard tissue

Applicant/Assignee: DENTSPLY RESEARCH AND DEVELOPMENT CORP

Application No.: 11/387177   Filing Date: 23/Mar/2006

Abstract:

One-component heat-curable sealant composition for the protection of exposed dental surfaces, comprising (a) a polymerisable monomer and/or oligomer which has at least two polymerizable double bonds per molecule, and (b) an initiator system comprising benzoylperoxide in an amount of at least 2 wt.-% based on the total composition.

Priority: EP20040018112 Applic. Date: 2004-07-30; WO2005EP08268 Applic. Date: 2005-07-29

Inventor: KLEE JOACHIM E [DE]; FACHER ANDREAS [DE]; WEBER CHRISTOPH [DE]; MULHAUPT ROLF [DE]; SCHMIDER MARTIN [DE]

Title: Methods for producing and purifying 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine monomers and polycarbonates derived therefrom

Applicant/Assignee: GENERAL ELECTRIC COMPANY SABIC INNOVATIVE PLASTICS IP B.V

Application No.: 11/263132   Filing Date: 31/Oct/2005

Abstract:

A polymer, article and blend including a polymer low yellowness index comprising structural units derived from a 2-hydrocarbyl-3,3-bis(4-hydroxyaryl)phthalimidine is disclosed.

Priority: US20050697139P Applic. Date: 2005-07-07

Inventor: CHATTERJEE GAUTAM [IN]; DHANABALAN ANANTHARAMAN [IN]; GLASGOW KATHERINE [US]; RAI VINOD KUMAR [IN]; SHANMUGAM SURESH [IN]; SRINIVASAN VEERARAGHAVAN [IN]

Title: Attachment integrated claims systems and operating methods therefor

Applicant/Assignee: INTEGRATED CLAIMS SYSTEMS, LLC

Application No.: 11/440583   Filing Date: 25/May/2006

Abstract:

Systems and methods for processing textual messages which are integrated with one or more digital attachments is described. These systems and methods are useful in the electronic filing and processing of, for example, image data, and of textual data associated with the image data. One particular application of these systems and methods would be for the electronic filing and processing of dental x-rays with patient claim forms.

Priority: US2002-196122 Applic. Date: 2002-07-17; US1997-823977 Applic. Date: 1997-03-25; US1997-823978 Applic. Date: 1997-03-25; US2000-587284 Applic. Date: 2000-06-05; US19960014427P Applic. Date: 1996-03-28; US2002-036432 Applic. Date: 2002-01-07; US2000-592256 Applic. Date: 2000-06-12; US1999-232805 Applic. Date: 1999-01-19; US1997-824010 Applic. Date: 1997-03-25; US2001-961308 Applic. Date: 2001-09-25; US2000-745489 Applic. Date: 2000-12-26

Inventor: DIRIENZO ANDREW L [US]

Title: Suspended fluid dispenser system and apparatus

Applicant/Assignee:

Application No.: 11/393196   Filing Date: 29/Mar/2006

Abstract:

A fluid dispenser comprises a container or fluid reservoir and a coupler. The container is adapted to be suspended from, and rotationally coupled to, a mounting point selected by a consumer. The container has at least one outlet at a first position in an outer surface thereof and further has the coupler located at a second position on the outer surface and attachable by a consumer to the selected mounting point in a repositionable relationship. The fluid dispenser further comprises position stabilization for maintaining the user-determined position of the container when not being acted upon, whereby a consumer controls fluid dispensing from the container by re-orienting the height of the outlet between any non-dispensing position and any dispensing position, without decoupling the container from the mounting point.

Priority: US20050670459P Applic. Date: 2005-04-11

Inventor: LICARI YAFFA S [US]

Title: Sterilization system and device

Applicant/Assignee:

Application No.: 11/477513   Filing Date: 30/Jun/2006

Abstract:

A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.

Priority: WO2005US00173 Applic. Date: 2005-01-06; US20040534395P Applic. Date: 2004-01-07; US20040575421P Applic. Date: 2004-06-01; US20040564589P Applic. Date: 2004-07-23

Inventor: ARNOLD ERNST V [US]; DOLETSKI BLAINE G [US]; DUNN THOMAS M [US]; RAULLI ROBERT E [US]; MUELLER EDWARD P [US]; BENEDEK KAREN R [US]; MURVILLE MARIE-LOUISE [US]

Title: Compositions and methods for controlling biofilms and bacterial infections

Applicant/Assignee:

Application No.: 11/181556   Filing Date: 14/Jul/2005

Abstract:

The present invention provides compounds and compositions useful for controlling bacterial biofilms as well as for controlling and/or preventing bacterial infections. The compounds of the invention are pentacyclic acid triterpenes. Methods for controlling biofilms and for controlling and/or preventing bacterial infections are also disclosed.

Priority:

Inventor: ELDRIDGE GARY R [US]; GOERING MATT [US]

Title: Collagen eucalyptus toothpaste

Applicant/Assignee:

Application No.: 11/182428   Filing Date: 16/Jul/2005

Abstract:

A toothpaste, dental cream, or mouth spray composition for soothing the gums and teeth has base ingredients such as sorbitol, hydrated silica, polyethylene glycol and water

and a combination of eucalyptus oil and collagen, being present at less than about 10% by weight.

Priority:

Inventor: CHIU CHIH-YUNG [TW]

Title: Methods and Systems for Treating Injured Cardiac Tissue

Applicant/Assignee: MEDTRONIC VASCULAR, INC

Application No.: 11/426219   Filing Date: 23/Jun/2006

Abstract:

Methods and systems are disclosed for treating injury to cardiac tissue by delivering a composition which provides structural support to the cardiac tissue. The composition helps to prevent chamber remodeling by providing structural reinforcement of the tissue or structural reinforcement of the tissue combined with biological therapy. The structurally reinforcing composition can thicken the wall of a heart, or act to prevent further thinning and thereby provide resistance against further remodeling. A number of compositions are disclosed, including multi-component substances such as autologous platelet gel, and other substances. The compositions disclosed can contain additives to augment/enhance the desired effects of the injection.

Priority: US20050693749P Applic. Date: 2005-06-23; US20060743686P Applic. Date: 2006-03-23

Inventor: NAYAK ASHA S [US]; KEOGH JAMES R [US]

Title: Medicated chewing gum delivery system for nicotine

Applicant/Assignee:

Application No.: 11/522441   Filing Date: 18/Sep/2006

Abstract:

A chewing gum delivery system has nicotine, gum base and a buffer system with an improved release rate for the nicotine. The resulting delivery system advantageously provides a convenient, reliable, practical, and relatively painless system for delivering an active. The delivery system is capable of delivering initial and second doses of a craving reduction active or other actives (e.g., nicotine), the combination of which rapidly reduces cravings, or provides some other pharmacological effect, and provides the pharmacological effect or protection from such cravings over a prolonged period of time beyond the initial dose. Notably, the delivery system is capable of rapidly achieving a pharmacologically effective concentration of the active (e.g., nicotine) in the bloodstream (e.g., within 5 minutes, or more desirably within 3 minutes, or in some cases, within 1-2 minutes), and is also capable of keeping the concentration of the active in the bloodstream at or near the pharmacologically effective concentration for at least 20 minutes after chewing of the delivery system begins, or more desirably about 30 minutes to about 50 minutes after chewing begins.

Priority: IE19980000991 Applic. Date: 1998-11-27; US2005-037098 Applic. Date: 2005-01-19; US2002-060349 Applic. Date: 2002-02-01; US1999-389339 Applic. Date: 1999-09-02; US1998-146696 Applic. Date: 1998-09-03

Inventor: CHERUKURI SUBRAMAN R [US]; PINNEY JOHN M [US]; HENNINGFIELD JACK E [US]; SASAN ARADHANA [US]; CONE EDWARD J [US]; SHIFFMAN SAUL [US]; GITCHELL JOE [US]; MALVESTUTTO CARLOS D [US]

Title: Teeth whitening apparatus and method

Applicant/Assignee:

Application No.: 11/481193   Filing Date: 05/Jul/2006

Abstract:

A dental whitening apparatus is provided that includes a body having a heating element and a light emitting device. The heating element and the light emitting device are disposed for activating a bleaching composition. A mouthpiece is connected with the body. The mouthpiece includes a dental receiving area that is formed of a material that facilitates transmission and emittance of light, and is contoured to a set of teeth. The dental receiving area has a first wall and a second wall that define a cavity. The cavity is configured for disposal of the bleaching composition. Methods of use are also disclosed.

Priority: US2004-925820 Applic. Date: 2004-08-25; US2005-120113 Applic. Date: 2005-05-02; US20030499692P Applic. Date: 2003-09-03; US20030498990P Applic. Date: 2003-08-29; US20030505196P Applic. Date: 2003-09-23; US20050666039P Applic. Date: 2005-03-29; US20050668664P Applic. Date: 2005-04-06

Inventor: HOCHMAN MARK [US]; CREAMER ALAN A [US]

Title: Message strip kit

Applicant/Assignee:

Application No.: 11/180856   Filing Date: 13/Jul/2005

Abstract:

A small, lightweight, portable message strip kit includes an elongated flexible band carrying a battery, electrical circuit, programmable computer chip and signaling device for alerting the user to perform a recommended activity at certain time intervals during various physical endeavors. The strip carries a program key for the computer chip to select the time intervals for the initiation of the signals. The kit has a chart relating user size, and physical endeavor to frequency of the signal for operation of the program key.

Priority:

Inventor: CONNELL BILL [US]

Title: Extracts from Ajuga reptans cell lines, their preparation and use

Applicant/Assignee: I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L

Application No.: 11/455505   Filing Date: 19/Jun/2006

Abstract:

The present invention relates to selected and stabilized cell line extracts from Ajuga reptans comprising phenylpropanoids having high antioxidating capacity with a teupolioside titre of between 20% and 90% and a chromophore-free fraction of between 80% and 10%. Said extracts are for use in human and veterinary therapy and for nutritional and cosmetic purposes. Furthermore, the invention relates to a novel phenylpropanoid molecule denominated isoteupolioside.

Priority: EP20050425441 Applic. Date: 2005-06-20; EP20050425585 Applic. Date: 2005-08-08

Inventor: DAL MONTE RENZO [IT]; DAL TOSO ROBERTO [IT]; MINGHETTI ANACLETO [IT]; CRESPI PERELLINO NICOLETTA [IT]; PRESSI GIOVANNA [IT]

Title: Diclofenac formulations and methods of use

Applicant/Assignee: APR APPLIED PHARMA RESEARCH SA

Application No.: 11/455120   Filing Date: 16/Jun/2006

Abstract:

Methods and formulations are provided for treating migraine and other acute pain episodes using diclofenac, and formulations of diclofenac that provide both rapid and sustained relief from acute pain. Methods and formulations are also provided for treating symptoms that often accompany migraine and acute pain such as photophobia, phonophobia, nausea and vomiting.

Priority: US20050692024P Applic. Date: 2005-06-17; US20050691757P Applic. Date: 2005-06-17

Inventor: REINER GIORGIO [IT]; REINER ALBERTO [IT]; MEYER ANDREAS [DE]

Title: DENTAL RESIN COMPOSITION, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF

Applicant/Assignee: PENTRON CLINICAL TECHNOLOGIES, LLC

Application No.: 11/456117   Filing Date: 07/Jul/2006

Abstract:

A composition is disclosed comprising a polymerizable oxetane-(meth)acrylate of the structure I: wherein R is hydrogen or methyl, R<1 >is a C1-6 alkyl group, n is 0-3, x is 1-3, y is 1-3, a is zero or one, and A is a linking group having the valency 1+y

and an effective amount of a cure initiator. The composition finds use as a dental resin.

Priority: US20050699751P Applic. Date: 2005-07-15

Inventor: JIN SHUHUA [US]; JIA WEITAO [US]

Title: MEDICAL AND DENTAL IMPLANT DEVICES FOR CONTROLLED DRUG DELIVERY

Applicant/Assignee: MICROCHIPS, INC

Application No.: 11/381646   Filing Date: 04/May/2006

Abstract:

Implantable devices and methods for use in the treatment of osteonecrosisare provided. The device includes at least one implant device body adapted for insertion into one or more channels or voids in bone tissue

a plurality of discrete reservoirs, which may preferably be microreservoirs, located in the surface of the at least one implant device body

and at least one release system disposed in one or more of the plurality of reservoirs, wherein the release system includes at least one drug selected from the group consisting of bone growth promoters, angiogenesis promoters, analgesics, anesthetics, antibiotics, and combinations thereof. The device body may be formed of a bone graft material, a polymer, a metal, a ceramic, or a combination thereof. The device body may be a monolithic structure, such as one having a cylindrical shape, or it may be in the form of multiple units, such as a plurality of beads.

Priority: US20060763336P Applic. Date: 2006-01-30; US20050727323P Applic. Date: 2005-10-17; US20050695030P Applic. Date: 2005-06-28

Inventor: SANTINI JOHN T JR [US]; HUTCHINSON CHARLES E [US]; PROOS ELIZABETH R [US]

Title: Lip augmentation device

Applicant/Assignee:

Application No.: 11/476591   Filing Date: 29/Jun/2006

Abstract:

The present invention is of a method of facilitating lip augmentation, the method comprising treating the lip area with an electricity generating device. The present invention further provides devices and kits for lip augmentation.

Priority: US20050695848P Applic. Date: 2005-07-05

Inventor: KARAT CAROL [IL]; TAL ISRAEL [IL]; MAVOR DANIELA [IL]; JAYES DALIA [IL]

Title: Therapeutic compositions and methods of use thereof

Applicant/Assignee:

Application No.: 11/527278   Filing Date: 26/Sep/2006

Abstract:

A method and composition for the restoration and maintenance of gingival and periodontal health are provided. The composition includes a potassium as an essential ingredient, which acts as an anti-bacterial agent. In some embodiments, the compositions include an osmotic agent other than potassium.

Priority: US2002-144235 Applic. Date: 2002-05-13; WO2000US31086 Applic. Date: 2000-11-13; US2000-633424 Applic. Date: 2000-08-07

Inventor: HODOSH MILTON [US]

Title: Oral composition containing non-aggregated zinc nanoparticles

Applicant/Assignee:

Application No.: 11/186510   Filing Date: 21/Jul/2005

Abstract:

An oral composition comprising a vehicle and a zinc ion source in the form of nanoparticles that are substantially non-aggregated and methods for use of such compositions are described. The composition provides antiplaque and anti malodor benefits to the user and the inclusion of nanoparticles permits a reduction in the amount of zinc ions present in the composition while maintaining efficacy.

Priority:

Inventor: BOYD THOMAS J [US]; XU GUOFENG [US]; VISCIO DAVID [US]; GAFFAR ABDUL [US]; ARVANITIDOU EVANGELIA S [US]; FRUGE LINH [US]

Title: Dental curing light having a short wavelength LED and a fluorescing lens for converting wavelength light to curing wavelengths and related method

Applicant/Assignee:

Application No.: 11/184433   Filing Date: 19/Jul/2005

Abstract:

A dental curing light includes a body, one or more LEDs configured to emit a first spectrum of light having a relatively short first peak wavelength (e.g., UV) disposed on the body, and a fluorescing lens that converts at least a portion of the first spectrum of light into a second spectrum of light having a second peak wavelength that is longer than the first peak wavelength. The second spectrum of light is selected so as to match the curing spectrum of a desired light-curable dental composition. In a preferred embodiment, the body comprises an elongate wand having a proximal end and distal end. The LEDs may be disposed at or near the distal end of the elongate wand.

Priority:

Inventor: SCOTT ROBERT R [US]; JESSOP DEE [US]

Title: Dental treating process using a treatment agent, dental tray, and a catalytic source

Applicant/Assignee:

Application No.: 11/489140   Filing Date: 19/Jul/2006

Abstract:

An improved process for treating teeth using a teeth cover, a treatment agent, and a catalytic source. The cover can be fitted by the wearer, instead of having to go to a dentist, by placing it against the teeth in one or both arches. A treatment agent is placed inside the cover, an external catalytic source catalyzes the agent, and the agent is placed against the teeth for a beneficial treatment. The treatment time is shortened by the process.

Priority: US20050700722P Applic. Date: 2005-07-20

Inventor: MADRAY GEORGE W [US]

Title: Cell handling device, human tissue regeneration composition, and human tissue regeneration method

Applicant/Assignee:

Application No.: 10/574816   Filing Date: 06/Apr/2006

Abstract:

The main objects of the present invention, which relates to regenerative medical treatments, are to enable (i) storage and conveyance of harvested or cultured cells without contamination occuring (ii) simple injection of the cells into a living body. To achieve these objects, cells harvested from a living body, or cells obtained by culturing harvested cells, are stored in a syringe-type storage vessel and subsequently transplanted into a living body. It is preferable that at least a part of the storage vessel inner wall in contact with the cells is formed from a cell non-adhesive material. Besides enabling cells in the vessel to take in the oxygen they require to survive, the present invention also enables cells quick and easy transplantation of cells into a living body without a cell detachment process, because cells are prevented from adhering to the inside of the vessel. Further, it is preferable that a stored tissue regeneration composition contains cell culture microcarriers floating in a fluidity medium, and that the cell culture microcarriers are composed of a bioabsorbable material and have cells adhering to their surfaces. Using this kind of tissue regeneration composition, a regenerative treatment can be carried out satisfactorily by simply and quickly transplanting cells from the syringe-type cell storage vessel into a living body without intricate scaffold-related procedures being required.

Priority: JP20030359936 Applic. Date: 2003-10-20; JP20030359935 Applic. Date: 2003-10-20; WO2003JP16397 Applic. Date: 2003-12-19

Inventor: YUGE RUI [JP]; MATSUURA YOJI [JP]; SAJIKI TOSHINOBU [JP]

Title: Processes and devices for the liquid treatment of suspended particles

Applicant/Assignee: EVOTEC TECHNOLOGIES GMBH

Application No.: 10/556239   Filing Date: 10/May/2004

Abstract:

Processes are described for the treatment of at least one particle ( 10 - 13 ) with at least one reaction liquid ( 20 ) in a main channel ( 30 ) of a fluidic microsystem ( 100 ) with the following steps: movement of the at least one particle ( 10 - 13 ) with a carrier liquid ( 40 ) flowing in a longitudinal direction of the main channel ( 30 ) up to a holding device ( 50 ), at least a temporary holding of the at least one particle ( 13 ) under the action of a holding force exerted by the holding device ( 50 ), and supplying of the reaction liquid ( 20 ) from at least one lateral channel ( 31 ) into the main channel ( 30 ) so that the at least one held particle ( 13 ) is rinsed by the reaction liquid ( 20 ), the holding device ( 50 ) being arranged downstream after a mouth ( 32 ) of the lateral channel ( 31 ) in the main channel ( 30 ) and the reaction liquid ( 20 )

flowing through the holding device ( 50 ) with a direction of flow running in the longitudinal direction of the main channel ( 30 ). Fluidic microsystems and electrode arrangements for realizing the processes are also described.

Priority: DE20031020869 Applic. Date: 2003-05-09; WO2004EP04981 Applic. Date: 2004-05-10

Inventor: SCHNELLE THOMAS [DE]

Title: Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Applicant/Assignee:

Application No.: 10/561986   Filing Date: 22/Dec/2005

Abstract:

This invention relates to novel aza-ring derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Priority: DK20030000941 Applic. Date: 2003-06-24; US20030482565P Applic. Date: 2003-06-26; WO2004EP51166 Applic. Date: 2004-06-18

Inventor: PETERS DAN [DK]

Title: Pyrimidine derivatives for the prevention of hiv infection

Applicant/Assignee:

Application No.: 10/544735   Filing Date: 04/Feb/2004

Abstract:

This invention concerns the use of a compound for the manufacture of a medicament for the prevention of HIV infection via sexual intercourse and related intimate contact between partners, wherein the compound is a compound of formula (I) a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein the ring containing -a<1>=a<2>-a<3>=a<4>- and -b<1>=b<2>-b<3>=b<4>- represents phenyl, pyridyl, pyrimidinyl, pirazinyl, pyridazinyl

and pharmaceutical compositions comprising them.

Priority: WO2003EP01291 Applic. Date: 2003-02-07; WO2004EP01011 Applic. Date: 2004-02-04

Inventor: HEERES JAN [BE]; LEWI PAULUS J [BE]; JANSSEN PAUL A J [BE]; DE JONGE MARC R [NL]; KOYMANS LUCIEN M H [BE]; DAEYAERT FREDERIK F D [BE]; VINKERS HENDRIK M [BE]; GUILLEMONT JEROME E G [FR]; PASQUIER ELISABETH T J [FR]; ARTS FRANK XAVIER J H [BE]

Title: Device for dental applications

Applicant/Assignee: JOHN A. KANCA, III

Application No.: 11/364278   Filing Date: 27/Feb/2006

Abstract:

Etching compositions, curable compositions, packaged products and methods of use for the treatment of bone substrate, i.e., teeth, are described. The etch solutions generally include an inorganic acid, an organic acid and either a solvent, a surfactant or mixtures thereof. The curable composites include reactive monomers and crosslinking agents that are effective to adhere to the surface of the treated substrate. The methods of the invention provide the ability to modify a bone or bone-like surface so that the curable composition, such as an adhesive resin, can be used in combination with a restorative material.

Priority: US2002-323865 Applic. Date: 2002-12-18; US20010341619P Applic. Date: 2001-12-18; US20020358883P Applic. Date: 2002-02-21

Inventor: KANCA JOHN A III [US]

Title: Dental hygiene device

Applicant/Assignee:

Application No.: 11/413923   Filing Date: 28/Apr/2006

Abstract:

A dental hygiene device including a finger-receiving portion 12 configured and dimensioned to snugly fit over at least a portion of a finger of a user (not shown) and a handle portion 14 extending from the finger-receiving portion 12 , the handle portion 14 being sufficiently long to permit gripping thereof by the hand of the user on which the finger-receiving portion 12 is mounted in use thereby to retain the finger-receiving portion 12 in place. The finger-receiving portion 12 indudes a cleaning pad 16 for cleaning teeth and gums of a person. The pad 16 is fixedly or removably mounted on the finger-receiving portion 12.

Priority: ZA20050006080 Applic. Date: 2005-07-29

Inventor: SCHEEPERS MARTHINUS J [ZA]

Title: Method for the production of an agent from larvae in flies for treating wounds and agent produced according to said method

Applicant/Assignee:

Application No.: 10/571218   Filing Date: 01/Sep/2006

Abstract:

The treatment of wounds by means of larvae from flies is improved by virtue of the fact that the larvae are contaminated with bacteriophages.

Priority: DE20031042104 Applic. Date: 2003-09-10; WO2004EP09244 Applic. Date: 2004-08-18

Inventor: FLEISCHMANN WIHELM [DE]

Title: Face mask particularly useful as medical face mask

Applicant/Assignee:

Application No.: 11/188907   Filing Date: 26/Jul/2005

Abstract:

A face mask particularly for dentists includes a masking band sized and configured to cover at least the mouth and nasal regions of the wearer

and a separate strip attached at its opposite ends to the opposite ends of the masking band. The intermediate portion of the separate strip carries an illustration of a smiling mouth in the mouth region, and is unattached to the masking band such that deformations of the masking band to accommodate itself to the face of the wearer is permitted by, and does not affect, the separate strip carrying the illustration of the smiling mouth.

Priority:

Inventor: ZALSMAN MOSHE [IL]

Title: Smoking article

Applicant/Assignee: R.J. REYNOLDS TOBACCO COMPANY

Application No.: 11/194215   Filing Date: 01/Aug/2005

Abstract:

A smoking article, such as a cigarette, includes a lighting end and a mouth end. The lighting end is a longitudinally extending segment comprising smokable material that is intended to be lit and burned, and the resulting smoke generated by the burning of that smokable material is intended to be drawn into the mouth of the smoker through the mouth end of smoking article. A mouth end piece is located at the mouth end of the smoking article, and the mouth end piece allows the smoking article to be placed in the mouth of the smoker to be drawn upon. The smoking article further incorporates an aerosol-generation system that is located between the lighting end segment and the mouth end piece.

The aerosol-generation system includes (i) a heat generation segment located adjacent to the lighting end segment, and (ii) an aerosol-generation region located between the heat generation segment and the mouth end piece. The aerosol-generation region incorporates an aerosol-forming material (e.g., glycerin and flavors). The lighting end segment is in a heat exchange relationship with the heat generation segment such that burning smokable material within the lighting end segment can ignite a combustible fuel element of the heat generation segment. The heat generation segment is in a heat exchange relationship with the aerosol-generation region such that heat generated by the burning fuel element acts to volatilize aerosol-forming material for aerosol formation.

Priority:

Inventor: CANTRELL DANIEL V [US]; CASEY WILLIAM J III [US]; CROOKS EVON L [US]; CONNER BILLY T [US]; TAYLOR JOANNE N [US]; WILLIS JEFFREY A [US]; BREWER DEMPSEY B JR [US]; DAVIS WAYNE E JR [US]; STONE JAMES R [US]

Title: Device for mixing and dispensing multi-component compositions

Applicant/Assignee: ERNST MUHLBAUER GMBH & CO. KG

Application No.: 11/543497   Filing Date: 05/Oct/2006

Abstract:

The device for mixing and dispensing multi-component compositions is distinguished in that a cap ( 10 ) acting as a closure initially closes the outlet openings ( 5 ) of the components and can be moved into the open position by pressure of the components while they are being discharged, so that the components can be mixed by the mixing helix ( 13 ) and emerge from the outlet tube ( 12 ). The device also includes distribution means that may be a fitted onto or an integral part of the outlet tube.

Priority: DE20021054409 Applic. Date: 2002-11-21; US2003-718393 Applic. Date: 2003-11-20

Inventor: HORTH HANS [DE]; REUSS STEFFEN [DE]; HOHNK HANS-DIETER [DE]

Title: Applicator with discrete pockets of a composition to be delivered with use of the applicator

Applicant/Assignee: KIMBERLY-CLARK WORLDWIDE, INC

Application No.: 11/193643   Filing Date: 29/Jul/2005

Abstract:

An applicator includes a tubular structure having a front panel that includes a liquid impermeable material and an outer liquid permeable cover material. A plurality of discrete pockets are formed between the cover material and the liquid impermeable material. A composition is contained within the pockets and, in use of the wipe, the composition migrates through the cover material during use of the applicator.

Priority:

Inventor: KECK LAURA E [US]

Title: Mechanisms of osteoinduction by LIM mineralization protein-1 (LMP-1)

Applicant/Assignee: EMORY UNIVERSITY

Application No.: 11/385612   Filing Date: 21/Mar/2006

Abstract:

The present invention relates to the methods and compositions for the treatment of subjects having compromised bone conditions. Specifically, the invention relates to combinatorial therapeutic strategies including small molecules and peptide mimics of LIM mineralization proteins, particularly LMP-1, to overcome the dose-related translational barriers for BMP-2 therapeutics.

Priority: US2003-399830 Applic. Date: 2003-07-25; WO2001US46044 Applic. Date: 2001-10-24; US20050664073P Applic. Date: 2005-03-22; US20050664074P Applic. Date: 2005-03-22; US20050736191P Applic. Date: 2005-11-10; US20060772322P Applic. Date: 2006-02-10; US20000242794P Applic. Date: 2000-10-24

Inventor: MARX JEFFREY C [US]; MCKAY WILLIAM F [US]; BODEN SCOTT D [US]

Title: Biaryl piperazinyl-pyridine analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 10/893799   Filing Date: 16/Jul/2004

Abstract:

Biaryl piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20030516135P Applic. Date: 2003-10-31; US20030488564P Applic. Date: 2003-07-16

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; BLUM CHARLES A [US]; BRIELMANN HARRY [US]; CHENARD BERTRAND L [US]; DE LOMBAERT STEPHANE [US]; HODGETTS KEVIN J [US]; HUTCHISON ALAN [US]; YOON TAEYOUNG [US]; ZHENG XIAOZHANG [US]

Title: SCREENING METHOD FOR THE IDENTIFICATION OF COMPOSITIONS SUITABLE FOR THE TREATMENT OF ORAL CAVITY MALODOR ASSOCIATED WITH SMOKING A TOBACCO PRODUCT

Applicant/Assignee: WM. WRIGLEY JR. COMPANY

Application No.: 11/461924   Filing Date: 02/Aug/2006

Abstract:

This invention generally relates to a screening method for identifying compositions suitable for use in an oral composition (e.g., a confection or chewing gum product) effective for the treatment of oral cavity malodor associated with smoking a tobacco product. In particular, this invention relates to a screening method for determining the ability of a composition to reduce the concentration of a pyridine or pyrazine compound present in a model sample or solution which is representative of the oral cavity of a subject after smoking a tobacco product, as an indicator of the effectiveness of that composition in the treatment of oral malodor associated with smoking a tobacco product.

Priority: US20050704597P Applic. Date: 2005-08-02

Inventor: BAZEMORE RUSSELL A [US]; HARRISON CHARLES J [US]

Title: Hybrid heat exchanger

Applicant/Assignee:

Application No.: 11/196573   Filing Date: 02/Aug/2005

Abstract:

A hybrid exchanger utilized to heat a working fluid utilizing counter current heat exchange from a heat source fluid. The plates of the hybrid heat exchanger are configured to be welded to provide a more robust design while also allowing optimum heat exchange of the working fluid. In another embodiment, the hybrid heat exchanger includes a plate assembly and shell combination construction. The plate assembly and shell combination provides both optimized counter current heat exchange, while also controlling leakage of fluid from the hybrid heat exchanger. The plates of hybrid heat exchanger have a plurality of fluid bores which facilitate the exchange of fluids including inlet and outlet ports for both the working fluid and the heat source fluid. The bores of the plates include an open mouth having a greater clearance which allows for optimized flow of fluid while also allowing for simplified cleaning and maintenance of the hybrid heat exchanger.

Priority:

Inventor: MIROLLI MARK D [US]

Title: Patient check system

Applicant/Assignee: SAGE PRODUCTS, INC

Application No.: 11/170995   Filing Date: 29/Jun/2005

Abstract:

A system for assisting in communication of the state of a patient's condition is disclosed. In an embodiment, a plastic container of washcloths includes two labels. The first label is mounted on the container and occludes an entry into the container. The second label also is mounted on the container via attachment to the first label. The second label includes a template that is mounted face down. In operation, the second label may be removed and observations regarding the patient's skin condition that are made during use of the washcloth can be marked on the template provided on the second label. The second label then may be communicated from one care provider to another care provider.

Priority:

Inventor: CHAPPUIS RON [US]

Title: SCREENING METHOD FOR IDENTIFICATION OF COMPOUNDS SUITABLE FOR TREATMENT OF ORAL CAVITY MALODOR ASSOCIATED WITH CONSUMPTION OF GARLIC

Applicant/Assignee: WM. WRIGLEY JR. COMPANY

Application No.: 11/461848   Filing Date: 02/Aug/2006

Abstract:

This invention generally relates to a screening method for identifying compositions suitable for use in an oral composition (e.g., a confection or chewing gum product) effective for the treatment of oral cavity malodor associated with the consumption of garlic. In particular, this invention relates to a screening method for determining the ability of a composition to reduce the concentration of a sulfide or disulfide compound (e.g., diallyl disulfide) present in a model sample or solution which is representative of the oral cavity of a subject after consuming garlic, as an indicator of the effectiveness of that composition in the treatment of oral cavity malodor associated with the consumption of garlic.

Priority: US20050704597P Applic. Date: 2005-08-02; US20050752678P Applic. Date: 2005-12-21

Inventor: BAZEMORE RUSSELL A [US]; HARRISON CHARLES J [US]; GREENBERG MICHAEL J [US]

Title: DNA sequences encoding novel growth/differentiation factors

Applicant/Assignee: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH

Application No.: 11/545480   Filing Date: 11/Oct/2006

Abstract:

The invention provides DNA sequences encoding novel members of the TGF-beta family of proteins. The. TGF-beta family comprises proteins which function as growth and/or differentiation factors and which are useful in medical applications. Accordingly, the invention also describes the isolation of the above-mentioned DNA sequences, the expression of the encoded proteins, the production of said proteins and pharmaceutical compositions containing said proteins.

Priority: EP19920102324 Applic. Date: 1992-02-12; DE19944423190 Applic. Date: 1994-07-01; US2005-105344 Applic. Date: 2005-04-14; US1999-901556 Applic. Date: 1999-09-24; US1994-289222 Applic. Date: 1994-08-12; WO1993EP00350 Applic. Date: 1993-02-12

Inventor: HOETTEN GERTRUD [DE]; NEIDHARDT HELGE [DE]; BECHTOLD ROLF [DE]; POHL JENS [DE]

Title: Cosmetic, pharmaceutical and dermatological preparations comprising homopolymer and/or copolymer waxes of the monomers ethylene and/or propylene

Applicant/Assignee:

Application No.: 11/449051   Filing Date: 08/Jun/2006

Abstract:

Cosmetic, pharmaceutical or dermatological preparations are described which comprise one or more homopolymer and/or copolymer waxes of the monomers ethylene and/or propylene. The homopolymer and copolymer waxes have a weight-average molecular weight Mw of less than or equal to 25 000 g/mol, a number-average molecular weight Mn of less than or equal to 15 000 g/mol, a molar mass distribution Mw/Mn in the range from 1.5 to 10 and have been obtained by metallocene catalysis. The copolymer waxes comprise, based on the total weight of the copolymer waxes, 0.1 to 30.0% by weight of structural units originating from the one monomer and 70.0 to 99.9% by weight of structural units originating from the other monomer.

Priority: DE200510026278 Applic. Date: 2005-06-08

Inventor: HERRMANN HANS-FRIEDRICH [DE]; LUKASCH ANTON [DE]; HOHNER GERD [DE]; MICHAELIS HEIKE [DE]; LACHMANN ANGELA [DE]

Title: Coated chewable confection

Applicant/Assignee:

Application No.: 11/498223   Filing Date: 02/Aug/2006

Abstract:

The present invention relates to coated chewable product that may provide separate and distinct textures and hardness levels in different segments of the product. More specifically, in some embodiments, the present invention provides a chewable confectionery product including: a dissolvable tablet core, which includes a first flavor

and a coating surrounding the tablet core, which includes a second flavor. The first flavor is different from the second flavor. Upon consumption, the confectionery product may provide a sequential release of the two different flavors.

Priority: US20050704704P Applic. Date: 2005-08-02

Inventor: ROBINSON MARY K [US]

Title: Mouth-moistening compositions, delivery systems containing same and methods of making same

Applicant/Assignee: CADBURY ADAMS USA LLC

Application No.: 11/503439   Filing Date: 11/Aug/2006

Abstract:

The present invention relates to compositions and comestibles that impart a mouth-moistening effect when orally consumed by an individual. More specifically, the compositions of the present invention may include a blend of components, such as a sweetening composition, food-grade acid composition and a cooling agent, that reduces or eliminates the perception of mouth dryness in an individual. The present invention also provides methods for preparing such comestibles, as well as methods of treating xerostomia by orally administering such comestibles.

Priority: US20050707759P Applic. Date: 2005-08-12

Inventor: LAKKIS JAMILEH [US]; EUAN DOROTHY [US]; PETTIGREW SUSAN [US]; BUGGE DIANE [US]

Title: Nozzle for dental composition

Applicant/Assignee: GC CORPORATION

Application No.: 11/493524   Filing Date: 27/Jul/2006

Abstract:

To separate a catalyst for polymerizing a monomer contained in a liquid or paste dental composition containing at least a monomer, such as a dental resin cement, an autopolymerizing dental resin or a resin-reinforced dental glass ionomer cement, from the liquid or paste dental composition to thereby improve storage stability of the dental composition and reduce number of division of the dental composition, an extrusion nozzle for a dental composition mounted on one end of an extruder for extruding a liquid or paste dental composition containing at least a monomer, the extrusion nozzle contains a catalyst for polymerizing the monomer contained in the dental composition during extrusion, and the catalyst is attached to an inner wall of an extruding channel of the extrusion nozzle.

Priority: JP20050228417 Applic. Date: 2005-08-05

Inventor: TOKUI HIDEKI [JP]; YARIMIZU HIDEKI [JP]; OTA DAISUKE [JP]; MORI TAKUYA [JP]; NAKASEKO HISASHI [JP]

Title: Device control module and method for controlling devices

Applicant/Assignee:

Application No.: 11/194997   Filing Date: 02/Aug/2005

Abstract:

A device control module and a method for controlling at least first and second devices based on operation of a foot pedal apparatus having a moveable member are provided. The device control module includes an RF receiver configured to receive a first RF signal at a first time indicating at least partial displacement of the moveable member of the foot pedal apparatus from a first operational position. The first RF signal has a first identifier value indicating the first device is to be controlled. The device control module further includes a processor operably coupled to the RF receiver. The processor is configured to activate the first device in response to the first RF signal. The RF receiver is further configured to receive a second RF signal at a second time after the first time.

The second RF signal indicates at least partial displacement of the moveable member of the foot pedal apparatus from the first operational position. The second RF signal has a second identifier value indicating the second device is to be controlled. The processor is further configured to activate the second device in response to the second RF signal.

Priority:

Inventor: WARNER THOMAS P [US]; DEZORZI TIMOTHY [US]; HASELHUHN HOWARD [US]

Title: System and method for remotely controlling devices

Applicant/Assignee:

Application No.: 11/194998   Filing Date: 02/Aug/2005

Abstract:

A system and a method for remotely controlling at least a first device based on operation of a foot pedal apparatus are provided. The foot pedal apparatus has a movable member. The system includes a first module configured to transmit a first RF signal in response to at least partial displacement of the moveable member of the foot pedal apparatus from a first operational position. The system further includes a second module configured to receive the first RF signal when a position of the second module is less than or equal to a threshold distance from the first module. The second module is configured to transmit a second RF signal in response to the first RF signal. The system further includes a third module configured to receive the second RF signal and to control operation of the first device in response to the second RF signal.

Priority:

Inventor: WARNER THOMAS P [US]; DEZORZI TIMOTHY [US]; HASELHUHN HOWARD [US]

Title: System and method for remotely controlling devices

Applicant/Assignee:

Application No.: 11/195040   Filing Date: 02/Aug/2005

Abstract:

A system and a method for remotely controlling at least a first device based on operation of a foot pedal apparatus are provided. The foot pedal apparatus has a movable member. The system includes a first module configured to transmit a first RF signal in response to at least partial displacement of the moveable member of the foot pedal apparatus from a first operational position. The first signal has a first identifier. The system further includes a second module configured to receive the first RF signal and to transmit a second RF signal having the first identifier and a second identifier in response to the first RF signal. The system further includes a third module configured to receive the second RF signal and to control operation of the first device in response to the second RF signal.

Priority:

Inventor: WARNER THOMAS P [US]; DEZORZI TIMOTHY [US]; HASELHUHN HOWARD [US]

Title: Aesthetic ceramic veneered restoration

Applicant/Assignee:

Application No.: 11/544681   Filing Date: 06/Oct/2006

Abstract:

The present invention relates to an aesthetic dental restoration having a layered structure, which dental restoration has the appearance of a natural tooth. In addition, the present invention relates to a method for preparing such dental restorations. Particularly, the invention is based on the control of interaction between opalescence and fluorescence.

Priority: EP20020078949 Applic. Date: 2002-09-20; US2003-668552 Applic. Date: 2003-09-22

Inventor: ZEL JOSEPH M V [NL]; APPELMAN PETRUS G [NL]; CORNELISSEN ERIC MARINUS H [NL]; DE KLER MARCEL A [NL]; GEBHARDT JURGEN [DE]

Title: New capped pyrazinoylguanidine sodium channel blockers

Applicant/Assignee: PARION SCIENCES, INC

Application No.: 11/195758   Filing Date: 03/Aug/2005

Abstract:

The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.

Priority:

Inventor: JOHNSON MICHAEL R [US]; MOLINO BRUCE F [US]; SARGENT BRUCE [US]; ZHANG JIANZHONG [US]

Title: SPHINGOSINE KINASE INHIBITORS AND METHODS OF THEIR USE

Applicant/Assignee: APOGEE BIOTECHNOLOGY CORPORATION

Application No.: 11/462153   Filing Date: 03/Aug/2006

Abstract:

The invention relates to compounds, pharmaceutical compositions thereof, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease,

Priority: US20050705608P Applic. Date: 2005-08-04

Inventor: SMITH CHARLES D [US]; FRENCH KEVIN J [US]; XIA ZUPING [US]

Title: Particle synthesis apparatus and method

Applicant/Assignee:

Application No.: 10/552390   Filing Date: 08/Apr/2004

Abstract:

An apparatus for dissolving or suspending a substance in a solvent comprising an outer chamber for containing a dense gas

an inlet for supplying dense gas as a solvent

a porous chamber within the outer chamber for containing a substance for dissolution or suspension with the solvent, the porous chamber having a wall which allows passage of solvent and the substance dissolved or suspended in the solvent, and an outlet for removing solvent and solution and/or dispersion from the outer chamber and a turbulence means for creating turbulence within the porous chamber. A method of dissolving or suspending a substance, and fine particles formed from the resulting solution or suspension are disclosed.

Priority: AU20030901645 Applic. Date: 2003-04-08; WO2004AU00466 Applic. Date: 2004-04-08

Inventor: FOSTER NEIL R [AU]; DEHGHANI FARIBA [AU]; COMBES GARY [GB]; REGTOP HUBERT L [AU]

Title: Therapeutic training straw

Applicant/Assignee: MCRT, LLC

Application No.: 11/202027   Filing Date: 12/Aug/2005

Abstract:

A drinking straw for controlling the intake of beverages, comprising an elongated hollow member having at least two open ends, at least one end being a suction end adapted for application of a suction force, and at least one end being a liquid end adapted for immersion in a liquid beverage

at least one compartment associated with each at least one suction end and located between the associated at least one suction end and the at least one liquid end and having openings for communicating the liquid beverage therethrough

and at least one insoluble object within the at least one compartment having an outer circumference smaller than an inner circumference of the at least one compartment

wherein the compartment openings and the object are dimensioned to prevent escape of the object from the compartment

and wherein the at least one object seals at least one compartment opening subsequent to the application of the suction force to prevent the movement of the liquid beverage past the opening.

Priority:

Inventor: PEARSON CALVIN M [US]

Title: Pharmaceutical multiparticulate composition comprising mycophenolic acid or mycophenolate sodium and combination with rapamycin

Applicant/Assignee:

Application No.: 10/570752   Filing Date: 01/Oct/2004

Abstract:

The present invention relates to a novel composition of mycophenolic acid, a salt or a prodrug thereof and to a fixed combination of mycophenolic acid, a salt or a prodrug thereof and rapamycin or a rapamycin derivative.

Priority: GB20030023202 Applic. Date: 2003-10-03; GB20030023598 Applic. Date: 2003-10-08; GB20030029852 Applic. Date: 2003-12-23; GB20040005902 Applic. Date: 2004-03-16; GB20040010714 Applic. Date: 2004-05-13; GB20040019356 Applic. Date: 2004-08-31; WO2004EP10998 Applic. Date: 2004-10-01

Inventor: BECKER DIETER [DE]; BURGER CARSTEN [DE]; FEUTREN GILLES [FR]; GUITARD PATRICE [FR]; KRAMER ANDREA [DE]; LOGGIA NICOLETTA [CH]; LUFTENSTEINER CHRISTIAN-PETER [CH]; OGORKA JORG [DE]; OTTINGER HARALD [DE]

Title: Drug delivery system for topical administration

Applicant/Assignee:

Application No.: 11/501839   Filing Date: 10/Aug/2006

Abstract:

This invention is directed to new drug delivery systems (SMS packaging(TM)) and uses thereof, of freshly prepared, effective, high concentrated, hygienic pharmaceutical compositions. The new delivery systems, including sucralfate, is used for treating and preventing oral diseases in mammals. Moreover this invention provides pharmaceutical compositions, methods and kits for topical administration to oral ulcers comprising sucralfate (Aftapet(TM) Aftakid(TM) Aftakit(TM) Chemokit(TM)). This invention is a platform delivery system for any drug, which needs a fresh mixture of powder and water,

Priority: US20050706757P Applic. Date: 2005-08-10

Inventor: SCHNEIDER MAYA [IL]

Title: Dental curing light including a light integrator for providing substantially equal distribution of each emitted wavelength

Applicant/Assignee:

Application No.: 11/200988   Filing Date: 10/Aug/2005

Abstract:

A dental curing light including a body having a housing, one or more light emitting devices disposed on or within the housing, and a light integrator configured to receive light emitted by the at least one light emitting device. The light integrator includes an outer wall defining a hollow reflective internal chamber, an input port through the wall, and an output port through the wall and spaced apart from the input port. Light is received by the light integrator through the input port and into the diffusely reflective internal chamber such that the received light is reflected in many directions and a plurality of times within the internal chamber before being emitted through the output port. Light exiting the output port of the light integrator is such that the intensity of any given wavelength emitted is substantially equally distributed across the entire footprint of emitted light.

Priority:

Inventor: SCOTT ROBERT R [US]; JESSOP DEE [US]

Title: Shuttered electrical connector socket

Applicant/Assignee: CLIPSAL AUSTRALIA PTY LTD

Application No.: 10/571541   Filing Date: 10/Sep/2004

Abstract:

A shuttered electrical connector for receiving an electrical plug, the plug having a hinged tail for lockingly engaging with the connector, is disclosed. The connector includes: a body 20 defining a socket having 22 an open mouth 24

a central shutter 30 hingedly mounted to the body 20 adjacent the open mouth 24 for rotation about a first hinge axis 32

and a pair of spaced apart side shutters 40 & 50 hingedly mounted to the body 20 adjacent the open mouth 24 for rotation about a second hinge axis 42, the second hinge axis 42 parallel to and spaced apart from the first hinge axis 32. The shutters are rotatable through approximately 90 degrees from: a closed position in which together they cover the open mouth 24 while presenting a substantially flat outer face, to an open position receiving the plug in which the central shutter is offset from the side shutters.

Priority: AU20030904963 Applic. Date: 2003-09-11; WO2004AU01222 Applic. Date: 2004-09-10

Inventor: KELLOCK ANDREW [AU]; COOK QUENTIN D [AU]

Title: Therapeutic compositions

Applicant/Assignee:

Application No.: 10/547613   Filing Date: 27/Feb/2004

Abstract:

The present invention provides compounds, compositions and methods for inhibiting or reducing reactive oxygen species (ROS) production in cells, such as in cells of the vascular system and in particular the smooth muscle-containing vasculature and/or endothelial cell-containing vasculature and/or adventitial fibroblast-containing vasculature. ROS production may also be inhibited in non-vascular cells of animals including mammals such as humans. Non-vascular cells contemplated herein include nerve cells, stem cells, progenitor cells and some cancer and rumor cells. More particularly, the present invention provides agents and even more particularly, cell-impermeable agents, capable of modulating NADPH oxidase activity, function or levels, thereby controlling superoxide production and production of downstream ROS. The present invention particularly enables agents which are selective against a form of Nox4-containing NADPH oxidase which has a portion of the enzyme such as all or part of the Nox4 component extracellularly exposed.

Priority: US20030450892P Applic. Date: 2003-02-28; WO2004AU00254 Applic. Date: 2004-02-27

Inventor: DUSTING GREGORY J [AU]; DRUMMOND GRANT R [AU]; SOBEY CHRISTOPHER G [AU]

Title: Separation of target acoustic signals in a multi-transducer arrangement

Applicant/Assignee: SOFTMAX, INC

Application No.: 11/463376   Filing Date: 09/Aug/2006

Abstract:

The present invention provides a process for separating a good quality information signal from a noisy acoustic environment. The separation process uses a set of at least two spaced-apart transducers to capture noise and information components. The transducer signals, which have both a noise and information component, are received into a separation process. The separation process generates one channel that is substantially only noise, and another channel that is a combination of noise and information. An identification process is used to identify which channel has the information component. The noise signal is then used to set process characteristics that are applied to the combination signal to efficiently reduce or eliminate the noise component. In this way, the noise is effectively removed from the combination signal to generate a good qualify information signal.

The information signal may be, for example, a speech signal, a seismic signal, a sonar signal, or other acoustic signal.

Priority: US2004-897219 Applic. Date: 2004-07-22

Inventor: VISSER ERIK [US]; LEE TE-WON [US]

Title: Dental compositions containing nanofillers and related methods

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/588764   Filing Date: 27/Oct/2006

Abstract:

The present invention features ionomer compositions containing nanofillers. The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.

Priority: US2004-847781 Applic. Date: 2004-05-17

Inventor: KANGAS LANI S [US]; BUI HOA T [US]; THALACKER JASON P [US]; KOLB BRANT U [US]; OXMAN JOEL D [US]; ROLF JACQUELINE C [US]

Title: Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 11/483488   Filing Date: 10/Jul/2006

Abstract:

A two-component initiator system having accelerators for curing polymerizable materials comprising the following components: (a) a hydroperoxide compound containing one or more hydroperoxide groups that are bound to a tertiary carbon

(b) a thiourea derivative

and (c) as accelerator, a copper compound which is soluble in the preparation is preferably free of amine and is particularly suited for polymerizable dental compositions.

Priority: DE200510039590 Applic. Date: 2005-08-19

Inventor: UTTERODT ANDREAS [DE]; HENNEN HEIKE [DE]

Title: Packaged dental composition

Applicant/Assignee:

Application No.: 11/586798   Filing Date: 26/Oct/2006

Abstract:

The invention provides a container enclosing an applicator and a dental composition including a volatile organic solvent. The container is sealed. The volatile organic solvent is effectively retained within the container, even after storage at about 43 DEG C. for one week. Preferably the container is made of a copolymer of a cycloolefin and an open chain olefin.

Priority: US2005-146975 Applic. Date: 2005-06-07; US2003-668946 Applic. Date: 2003-09-23; US20020319581P Applic. Date: 2002-09-27

Inventor: PIERSON PAUL R [US]; HAMMESFAHR PAUL D [US]

Title: Precipitation hardenable austenitic steel

Applicant/Assignee: SANDVIK INTELLECTUAL PROPERTY AB

Application No.: 11/487442   Filing Date: 17/Jul/2006

Abstract:

The present invention relates to a stainless steel alloy, more precisely a highstrength stainless, precipitation hardenable, austenitic, stainless alloy, containing a well adjusted amount of aluminium and a high silicon content and which has the following composition (in weight-%): C 0-0.07 Si 0.5-3.0 N 0-0.1 Cr 15.0-20.0 Ni 7.0-12.0 Al 0.25-1.5 Cu 0

Priority: SE20010004192 Applic. Date: 2001-12-11; US2005-496491 Applic. Date: 2005-02-01; WO2002SE02300 Applic. Date: 2002-12-11

Inventor: ZETTERHOLM GUSTAF [SE]; HOLMBERG HAKAN [SE]

Title: Tooth coating composition

Applicant/Assignee: HANIX CO., LTD

Application No.: 10/556914   Filing Date: 26/Aug/2004

Abstract:

The invention provides a tooth coating composition for beauty and appearance and prevention of dental caries and excellent in the quick drying property, durability, color tone, luster, and removal easiness by using shellac and rosin as main components and a pigment, a pigment dispersant, a dye, an efficacious component having anti-dental caries function, an anti-bacterial agent, a tackifier, a luster reflecting material, a bleaching agent, and a flavor as auxiliary components.

Priority: JP20030302282 Applic. Date: 2003-08-27; WO2004JP12698 Applic. Date: 2004-08-26

Inventor: URAI KAORUKO [JP]; TODOROKI REIKO [JP]

Title: Inhibition of bacterial deposition on oral surfaces

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 11/205879   Filing Date: 17/Aug/2005

Abstract:

The invention is directed to an oral composition that contains an amphoteric surfactant and an homo- or copolymer comprising an ethylenic monomer and related methods. The ethylenic monomer includes a phosphonate group. The monomer may be represented by the structure of Formula (I): wherein one of A and A' is a hydrogen atom and the other is selected from a hydrogen atom or a group -(X)nRm

wherein n is i\selected from 0 or 1

provided that when n is 0, m is 1, and when n is 1, m is an integer of 1 to 3

X is selected from an oxygen atom, a sulfur atom, a nitrogen atom, a phosphorous atom, and silicon atom

R is independently a hyuderogen atom or an arganic radical

L is selected from a bond and a linking group

M and M' are independently selected from a hydrogen atom, an alkali metal, and an ammonium ion, or together form an alkaline earth metal or other divalent element

and p is 1 or 2, provided that when L is a bond, p is 1.

Priority:

Inventor: GAFFAR ABDUL [US]; BOYD THOMAS J [US]

Title: Methods and Systems for Treating Injured Cardiac Tissue

Applicant/Assignee: MEDTRONIC VASCULAR, INC

Application No.: 11/426211   Filing Date: 23/Jun/2006

Abstract:

Methods and systems are disclosed for treating injury to cardiac tissue by delivering a composition which provides structural support to the cardiac tissue. The composition helps to prevent chamber remodeling by providing structural reinforcement of the tissue or structural reinforcement of the tissue combined with biological therapy. The structurally reinforcing composition can thicken the wall of a heart, or act to prevent further thinning and thereby provide resistance against further remodeling. A number of compositions are disclosed, including multi-component substances such as autologous platelet gel, and other substances. The compositions disclosed can contain additives to augment/enhance the desired effects of the injection.

Priority: US20050693749P Applic. Date: 2005-06-23; US20060743686P Applic. Date: 2006-03-23

Inventor: NAYAK ASHA S [US]; KEOGH JAMES R [US]

Title: Nozzle piece for a dental powder jet apparatus

Applicant/Assignee:

Application No.: 10/564043   Filing Date: 25/May/2004

Abstract:

A nozzle piece for a dental powder jet apparatus is provided with a discharge nozzle, the outlet cross section of which is formed by few nozzle openings in the lateral area of the front end of a tube-shaped partial length of the nozzle piece, for a primarily sub-gingival cleaning of the tooth radix surfaces with particularly fine-grained dental powders.

Priority: DE20031031583 Applic. Date: 2003-07-11; WO2004EP05610 Applic. Date: 2004-05-25

Inventor: PICHAT PATRICK [FR]; HENRY NICOLE [CH]; MEISSNER ROLF [CH]; MENNE ANDREAS [CH]

Title: Modulators of muscarinic receptors

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 11/359960   Filing Date: 22/Feb/2006

Abstract:

The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Priority: US2005-208386 Applic. Date: 2005-08-19; US20040602731P Applic. Date: 2004-08-19

Inventor: MAKINGS LEWIS R [US]; BLANCO MIGUEL G [US]; HURLEY DENNIS J [US]; DRUTU IOANA [US]; RAFFAI GABRIEL [US]; BERGERON DANIELE M [US]; NAKATANI AKIKO [US]; TERMIN ANDREAS P [US]; SILINA ALINA [US]

Title: Substituted heterocyclic diarylamine analogues

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 10/564431   Filing Date: 09/Jul/2004

Abstract:

Substituted heterocyclic diarylamine analogues of Formula I are provided: wherein X, Y and Z are independently N or optionally substituted C, and other variables are as described in the specification. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20030486133P Applic. Date: 2003-07-10; WO2004US22326 Applic. Date: 2004-07-09

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; HODGETTS KEVIN J [US]; HUTCHISON ALAN [US]; OHLIGER ROBERT [US]; YOON TAEYOUNG [US]; ZHENG XIAOZHANG [US]

Title: 2-Methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts

Applicant/Assignee: NEUROSEARCH A/S

Application No.: 10/566384   Filing Date: 29/Jul/2004

Abstract:

This invention relates to novel (1R,2R,3S,5S)-2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts, such as L-tartrate monohydrates and anhydrates. The salts are useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these salts in a method for therapy and to pharmaceutical compositions comprising the salts of the invention.

Priority: DK20030001117 Applic. Date: 2003-07-31; US20030494090P Applic. Date: 2003-08-12; WO2004EP51651 Applic. Date: 2004-07-29

Inventor: FROSTRUP BRIAN [DK]; WATJEN FRANK [DK]; JENSEN KLAUS S [DK]

Title: Free-radical initiator systems containing enzymes, compositions, and methods

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/586947   Filing Date: 26/Oct/2006

Abstract:

A free-radical initiator system that includes a combination of an oxidase enzyme, a peroxidase coenzyme, an oxidase substrate, and a reductant (i.e., reducing agent). This system can be used with a resin system that includes a polymerizable component.

Priority: US2002-327202 Applic. Date: 2002-12-20

Inventor: WU DONG [US]; OXMAN JOEL D [US]

Title: Drug delivery device comprising a mesh sleeve

Applicant/Assignee:

Application No.: 10/550965   Filing Date: 26/Mar/2004

Abstract:

This invention concerns drug delivery by way of mesh sleeves for use with devices adapted for insertion into the vagina, rectum, nasal or buccal cavity. The resulting apparatus exploit the highly vascularised nature of the tissue of bodily cavities such as the vagina, nose, rectum and mouth to deliver pharmaceutical agents to localised areas and/or into underlying tissues.

Priority: GB20030006977 Applic. Date: 2003-03-26; WO2004GB01311 Applic. Date: 2004-03-26

Inventor: KNOX PETER [GB]

Title: Emergency management system

Applicant/Assignee:

Application No.: 11/502484   Filing Date: 10/Aug/2006

Abstract:

The present disclosure relates to systems and methods for: 1) displaying all vital central station (CS) information and controls on a single screen

2) linking peripheral central stations (pCSs) to a master central station (mCS)

3) operating the system disclosed in U.S. Ser. No. 10/460,458, without medical professionals (MPs) in the mCS or without any mCS

4) linking a remote controlled defibrillator (RCD(TM)) unit to an arrest sensor

5) operating an RCD unit in a motor vehicle and linking an RCD unit to a vehicle communications system

6) linking an RCD unit to a CS through a network of: a) non-vehicle-based stationary units (SUs), b) vehicle-based SUs/vehicle communication systems, or c) non-vehicle-based SUs and vehicle-based SUs/vehicle communication systems

7) using an RCD unit with a chest compression device

8) using the network of RCD units and MPs for disaster monitoring

and 9) monitoring and treating hospital patients and motor vehicle passengers.

Priority: US20050709078P Applic. Date: 2005-08-17

Inventor: MATOS JEFFREY A [US]

Title: Trash can stretchy

Applicant/Assignee:

Application No.: 11/217042   Filing Date: 31/Aug/2005

Abstract:

The Stretchy is a circular-shaped form made by either stitching the opposite ends together to make a circular cohesive single piece with a hole naturally formed as a result on the inside where the waste fits neatly through or a singular piece of material or fabric able to be stretched over the lip or rim of the wastebasket opening. Elastic material is inserted around the top and bottom edges of the stitched-together fabric to allow the entire formation to mold itself around the top of the trash can of varying sizes. Lace and other trinkets can adorn the invention accordingly.

Priority:

Inventor: LAWSON LILLIAN [US]

Title: Method of determining the shape of a dental technology object and apparatus for per-forming the method

Applicant/Assignee:

Application No.: 11/507555   Filing Date: 22/Aug/2006

Abstract:

The invention relates to a method and an apparatus for a non-contact, three-dimensional determination of the shape of a dental technology object ( 10 ) whereby, to determine the space coordinates of the object's surface points to be measured, a thin stripe of light projected onto the object is measured by at least two matrix cameras ( 32, 34 ) to determine two space coordinates (Z- Y-coordinate) of a coordinate system, and the third space coordinate (X coordinate) is ascertained by determining the position of the object arranged on a measuring table ( 22 ) which is rotatable about an axis of rotation ( 20 ). For allowing, in an easy manner, a non-contact determination of the shape of the dental technology object, whereby the constructive effort to determine the spatial coordinates is kept low and the shape acquisition should still be performed highly precisely and at high speed, it is provided that the matrix camera is a color matrix camera with first, second and third pixels, that the matrix camera captures light in a range of wave lengths characteristic for one type of the pixels (first pixels) and the values at least of one of the other types of the pixels (second and third pixels) are analyzed to determine the two first location coordinates (Y- and Z-coordinates).

Priority: DE200510040282 Applic. Date: 2005-08-24; EP20050022072 Applic. Date: 2005-10-11

Inventor: BRINKMANN HARTMUT [DE]; FECHER STEFAN [DE]; VOLKL LOTHAR [DE]; JAUMANN RALF [DE]

Title: EXTENDED LIP WICKET SLIDER DELI BAG

Applicant/Assignee: ILLINOIS TOOL WORKS INC

Application No.: 11/465969   Filing Date: 21/Aug/2006

Abstract:

A flexible reclosable container with a header strip, fastener elements, and a slider. The header strip preferably extends from the mouth of the bag, and includes a line of weakness for easy tear off of the bag. The slider and profiles are arranged such that the mouth of the bag is substantially open.

Priority: US2002-107694 Applic. Date: 2002-03-27

Inventor: KEITH DAVID W [US]; EDELMAN PAUL F [US]

Title: Methods and compositions for the treatment of diseases characterized by calcification and/or plaque formation

Applicant/Assignee: NANOBAC PHARMACEUTICALS, INC

Application No.: 11/544048   Filing Date: 06/Oct/2006

Abstract:

The invention provides methods and compositions that include a nutraceutical supplement, antibiotic, and metal chelating agent that is administered to a patient to treat or prevent pathological calcification and or plaque formation as associated with Nanobacteria Calcifying Nano-Particles and/or diseases caused there-from, The method includes the administration of a therapeutically effective nutraceutical supplement, tetracycline HCL, and ethylenediaminetetraacetic acid calcium di-sodium salt to a patient in order to prevent and treat calcific disease.

Priority: US2005-182076 Applic. Date: 2005-07-15; US20040587871P Applic. Date: 2004-07-15

Inventor: KAJANDER E O [US]; AHO K [FI]; CIFTCIOGLU NEVA [US]; MILLICAN H B [US]; MANISCALCO B [US]

Title: Combination therapies for inhibiting integrin-extracellular matrix interactions

Applicant/Assignee:

Application No.: 11/508754   Filing Date: 22/Aug/2006

Abstract:

The present application relates to compositions of ECM antagonists and their use in methods for treating angiogenic-dependent conditions. The ECM antagonists can bind the same or different ECM component. The present application also relates to compositions of ECM antagonists and cancer therapies and their use in methods for preventing, treating or managing angiogenic dependent conditions such as cancer.

Priority: US20050711060P Applic. Date: 2005-08-24

Inventor: VAN EPPS DENNIS [US]; FREIMARK BRUCE [US]; BROOKS PETER C [US]

Title: Structured materials

Applicant/Assignee:

Application No.: 11/216695   Filing Date: 31/Aug/2005

Abstract:

The present invention relates to a method for preparing a structured material comprising: providing a hydrophilic particle such as hydrophilic silicas, silicates, dextrins, starches, minerals, sodium bicarbonate, clays, sugars, polyols, dried flavors/fragrances, hydrocolloids, proteins, celluloses, methylcellulose, hydroxypropyl methyl cellulose, flours of wheat, corn, potato, and rice, dried milk and dairy powders, spice, herb, and vegetable powders, meat powders, salts, and acids

providing a hydrophobic active ingredient selected from the group consisting of flavors, fragrances, pharmaceutical and nutritional agents, and/or an appropriate hydrophobic carrier such as triglyceride oils, triglyceride fats and mineral oils

providing a polyhydric material such as glycerine, propylene glycol, dipropylene glycol, polyethylene glycol, aqueous solutions of sorbitol, isomalt, lactitol, maltitol, aqueous solutions of sugars, starches, acids, polyethylene glycols, dextrins, and water soluble or swellable compounds, or water

and admixing said hydrophilic particle, said active ingredient and said polyhydric material to form said structured material. The above method of the present invention will be apparent by reading the following specification.

Priority:

Inventor: POPPLEWELL LEWIS M [US]; HENSON LULU [US]

Title: Diaminopyrimidines as P2X3 and P2X2/3 modulators

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 11/509890   Filing Date: 25/Aug/2006

Abstract:

Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the compounds being of formula (I): wherein D, X, R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7 >and R<8 >are as defined herein.

Priority: US20050713398P Applic. Date: 2005-09-01

Inventor: DILLON MICHAEL P [US]; JAHANGIR ALAM [US]; LIN CLARA J J [US]

Title: Diaminopyrimidines as P2X3 and P2X2/3 modulators

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 11/510015   Filing Date: 25/Aug/2006

Abstract:

Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein A, D, E, G, J, X, Y, Z R<6>, R<7 >and R<8 >are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.

Priority: US20050713243P Applic. Date: 2005-09-01

Inventor: DILLON MICHAEL P [US]; JAHANGIR ALAM [US]; LUI ALFRED S [US]; WILHELM ROBERT S [US]

Title: DENTAL RESIN COMPOSITION, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF

Applicant/Assignee: PENTRON CLINICAL TECHNOLOGIES, INC

Application No.: 11/469574   Filing Date: 01/Sep/2006

Abstract:

A curable restorative composition is disclosed, comprising a polymerizable mono(meth)acrylate resin having a vapor pressure of 1 mm Hg or less at 20 DEG C., a plasticizer

and a curing system for the mono(meth)acrylate resin. The composition is particularly useful for making temporary restorations. Methods of used and kits comprising the composition are also disclosed.

Priority: US20050713249P Applic. Date: 2005-09-01; US20060765272P Applic. Date: 2006-02-03

Inventor: JIA WEITAO [US]; JIN SHUHUA [US]

Title: Diaminopyrimidines as P2X3 and P2X2/3 modulators

Applicant/Assignee: ROCHE PALO ALTO LLC

Application No.: 11/510216   Filing Date: 25/Aug/2006

Abstract:

Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): wherein D, X, R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7 >and R<8 >are as defined herein.

Priority: US20050713399P Applic. Date: 2005-09-01

Inventor: DILLON MICHAEL P [US]; JAHANGIR ALAM [US]; MOORE AMY G [US]; WAGNER PAUL J [US]

Title: Oral hygiene device

Applicant/Assignee: DAVID R. SHARP

Application No.: 11/217267   Filing Date: 01/Sep/2005

Abstract:

An oral hygiene device includes an anti-microbial compound which is applied to tissues in the mouth to freshen breath or otherwise inhibit the growth of bacteria. In one embodiment, the anti-microbial compound is combined with a tongue scraper to remove bacteria and other contaminants from the tongue prior to application of the anti-microbial compound. The anti-microbial compound typically includes a anti-microbial agent and a binding and tactifying agent, and can have flavoring, sweeteners, and abrasives added.

Priority:

Inventor: ANDERSEN SCOT N [US]

Title: TONGUE CLEANING DEVICE WITH DISSOLVABLE BLISTER

Applicant/Assignee:

Application No.: 11/553620   Filing Date: 27/Oct/2006

Abstract:

A device for cleaning the tongue and mouth is formed to have beneficial surface features. Depressions are formed on one surface of the device to facilitate adhering the device to the roof of the mouth. Dissolvable blisters are formed on one surface to contain and deliver a material, such as mouthwash or medicine, into the mouth of the user. The blisters may formed with different wall thicknesses to provide a time-controlled release of the deliverable material.

Priority: US2005-093785 Applic. Date: 2005-03-29

Inventor: MYTHEN DANIEL R [US]

Title: Welder's helmet with respirator

Applicant/Assignee:

Application No.: 11/208344   Filing Date: 19/Aug/2005

Abstract:

A welder's helmet is provided including a welder's mask having a sight window and at least one opening in the mask for accommodating a filter cartridge of a respirator mask. The respirator mask is independently strapped to the user's head to assure proper airtight fit to the user's face. A foam mounting structure is formed from a plurality of spacer strips that allow the user to customize the spacing between the welder's mask and respirator mask to fit their individual size requirements. A pair of respirator cartridges can be utilized to extend from the sides of the welder's helmet so as not to provide an obstruction in front of the user's face.

Priority:

Inventor: CHARLES STEVEN [US]

Title: Apparatus and method of cleaning teeth

Applicant/Assignee:

Application No.: 11/221542   Filing Date: 08/Sep/2005

Abstract:

This invention discloses an apparatus and method for cleaning teeth, particularly in individuals undergoing cosmetic and orthodontic treatment. The apparatus includes members having a tooth contact portion and a handle portion. Connected to the tooth contact portion is a floss tip enclosure element capable of receiving floss that is capped. The invention can be used easily and conveniently to enable a person to floss underneath bridges, or orthodontic wiring, without damage to the gingival tissue.

Priority:

Inventor: STELMACH THOMAS [US]

Title: LED illuminator with retro reflector

Applicant/Assignee: INNOVATIONS IN OPTICS, INC

Application No.: 11/593965   Filing Date: 07/Nov/2006

Abstract:

An illuminator with blue and red LEDs, a reflector upstream of the LEDs for capturing upstream light emitted out of the back surfaces of the LEDs and redirecting downstream as useful illumination, a band pass filter for conditioning the downstream light, a phosphor layer for changing the spectral properties of light from the LEDs, and a non-imaging concentrator for creating a beam of illumination over a predetermined solid angle, uniformity, and spectral content.

Priority: US2002-334525 Applic. Date: 2002-12-30; US20010346090P Applic. Date: 2001-12-31; US20010346181P Applic. Date: 2001-12-31; US20010346182P Applic. Date: 2001-12-31; US20010346183P Applic. Date: 2001-12-31; US20010346184P Applic. Date: 2001-12-31

Inventor: BRUKILACCHIO THOMAS J [US]

Title: High intensity LED array illuminator

Applicant/Assignee: INNOVATIONS IN OPTICS, INC

Application No.: 11/594377   Filing Date: 08/Nov/2006

Abstract:

A high intensity mutli-wavelength illumination apparatus comprising an array of LEDs each of which has a predetermined spectral output that is emitted over a predetermined solid angle, an array of non-imaging concentrators the individual non-imaging concentrators of which are optically coupled in one-to-one correspondence with the LEDs, each non-imaging concentrator in the array of non-imaging concentrators operating to collect radiation emitted by each of the LEDs and to re-emit substantially all the collected radiation as a beam having a diverging solid angle smaller than said predetermined solid angle over which radiation is emitted by each of the LEDs,

the non-imaging concentrators each having an entrance aperture for receiving radiation emitted by a corresponding one of the LEDs and an exit aperture from which the LEDs output emerges spatially and spectrally uniform in the near field of the exit aperture, and a light integrator having an entrance facet optically coupled to each of the exit apertures of the non-imaging concentrators for receiving radiation there through and conducting it to an exit facet thereof from which radiation is emitted for a downstream application, the light integrator being structured and arranged to substantially uniformly mix the individual beams emitted by each concentrator so that radiation emitted from its exit facet is uniformly colored.

Priority: US2002-334525 Applic. Date: 2002-12-30; US20010346090P Applic. Date: 2001-12-31; US20010346181P Applic. Date: 2001-12-31; US20010346182P Applic. Date: 2001-12-31; US20010346183P Applic. Date: 2001-12-31; US20010346184P Applic. Date: 2001-12-31

Inventor: BRUKILACCHIO THOMAS J [US]

Title: Bag attachment for cooler

Applicant/Assignee:

Application No.: 11/513252   Filing Date: 31/Aug/2006

Abstract:

The bag attachment for a cooler includes a pouch defining a bag having a frame disposed about the mouth of the bag. The frame is releasably attached to an external wall of a cooler and maintains the mouth of the pouch in an open state, allowing for the storage of waste, such as empty cans and bottles, in the receptacle. When the pouch is full, the frame may be detached from the cooler and closed to seal the mouth of the bag for transport to a waste depository.

Priority: US20050713358P Applic. Date: 2005-09-02

Inventor: PLOUFF ROCKEY J [US]

Title: Unit dose delivery system

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/593250   Filing Date: 06/Nov/2006

Abstract:

The invention includes a delivery system for a composition made of two or more components, the assembly of a container for use in the system, a method for providing a composition, and a delivery system including an applicator and container. In one embodiment, the container includes an outer housing holding a first mass of a first component of the composition, an inner housing holding a second mass of a second component of the composition, and a seal. The first component is a liquid and the mass of the second component conforms to a bottom and side wall of the inner housing. An interference fit exists between the outer housing and the inner housing such that the inner housing seals the first mass within the first chamber. The inner housing has an aperture in a side wall of the second chamber.

Priority: US2004-798649 Applic. Date: 2004-03-11

Inventor: LEE ROBERT [US]; MEYERTHOLEN DARIN J [US]; BROYLES BRUCE R [US]; KRUEGER DANIEL D [US]

Title: Antimicrobial materials for dental care applications

Applicant/Assignee:

Application No.: 11/599758   Filing Date: 15/Nov/2006

Abstract:

The invention pertains to antimicrobial dental care materials. In particular, the invention pertains to antimicrobial dental care materials containing biocidal complexes, e.g.: a) a mouthwash containing said complex

b) a dentifrice containing said complex

c) a dental floss coated and/or impregnated with said complex

and d) a protective coating for teeth containing said complex, e) toothbrush bristles coated and/or impregnated with said complex

f) an orthodontic appliance coated and/or impregnated with said complex

g) an orthodontic appliance adhesive containing said complex

h) a denture appliance coated and/or impregnated with said complex

I) a denture appliance adhesive containing said complex

j) an endodontic composition coated and/or impregnated with said complex

k) a composite-type dental restorative composition containing said complex

l) a dental cement containing said complex

m) a dental liner containing said complex

n) a dental bonding agent containing said complex

The complex will have a maximum water solubility of about 5 wt. % and is further characterized as being a complex that is formed by a metathesis reaction between a biocidal cationic monomer or polymer with a biocidal anionic monomer or polymer or by an acid-base reaction between a biocidal monomeric or polymeric free base and a biocidal monomeric or polymeric acid capable of protonating the free base.

Priority: US2003-647752 Applic. Date: 2003-08-26

Inventor: STOCKEL RICHARD F [US]

Title: Oral care compositions containing combinations of anti-bacterial and host-response modulating agents

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY

Application No.: 11/595530   Filing Date: 10/Nov/2006

Abstract:

The present invention encompasses topical oral care compositions comprising the combination of an anti-bacterial agent with an anti-inflammatory agent in an orally acceptable carrier for effective treatment and prevention of bacteria-mediated diseases and conditions in the oral cavity and for modulating host reaction to bacterial pathogens present in the oral cavity and to the toxins, endotoxins, inflammatory cytokines and mediators released by or prompted by these pathogens. The present invention also encompasses methods of use of these compositions comprising topical application to the oral cavity. The benefits of the present compositions and methods extend beyond treating and preventing oral bacterial infections in the oral cavity to promoting whole body or systemic health.

Priority: US2000-607602 Applic. Date: 2000-06-30

Inventor: DOYLE MATTHEW J [US]; LAUGHLIN LEO T [US]; UNDERINER TODD L [US]; HO BEGONIA Y [US]; GRAYLING ROWAN A [US]

Title: Aqueous sanitizers, disinfectants, and/or sterilants with low peroxygen content

Applicant/Assignee: SOLUTIONS BIOMED, LLC

Application No.: 11/510516   Filing Date: 24/Aug/2006

Abstract:

The present invention is drawn to disinfectant compositions, which are human safe, e.g., food grade or food safe. In one embodiment, an aqueous disinfectant composition can comprise an aqueous vehicle, including water, from 0.001 wt % to 10.0 wt % of a peroxygen, and an alcohol. Additionally, from 0.001 ppm to 50,000 ppm by weight of a transition metal based on the aqueous vehicle content can also be present. The composition can be substantially free of aldehydes. Alternatively or additionally, the transition metal can be in the form of a colloidal transition metal, such as colloidal silver or alloy thereof.

Priority: US2006-361836 Applic. Date: 2006-02-24; US2006-361841 Applic. Date: 2006-02-24; US2006-361837 Applic. Date: 2006-02-24; US2006-361665 Applic. Date: 2006-02-24; US20050656723P Applic. Date: 2005-02-25

Inventor: TICHY DARYL J [US]; LARSON BRIAN G [US]

Title: Personal care compositions with silicones and dihydroxypropyl trialkyl ammonium salts

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER CONOPCO, INC

Application No.: 11/222189   Filing Date: 08/Sep/2005

Abstract:

A personal care composition is provided with a silicone compound and being aesthetically modified for improved skinfeel with a quaternary ammonium salt, the salt having a structure AB, wherein A is a cationic charged component, B is an anionic charged component, and A has one quaternized nitrogen atom, at least two hydroxyl groups and a molecular weight no higher than about 250.

Priority: US2004-972483 Applic. Date: 2004-10-25

Inventor: HURLEY MEGAN K [US]; MINER PHILIP E [US]; BARROW STEPHEN R [US]; CHANDAR PREM [US]; MCMANUS RICHARD L [US]; HARICHIAN BIJAN [US]

Title: Breath freshening confectionery products and methods of making and using same

Applicant/Assignee:

Application No.: 11/349526   Filing Date: 06/Feb/2006

Abstract:

A confectionery product comprises a first side and a second side generally opposite to said first side, and a product thickness. The second side comprises an abrasive surface that is suitable for cleaning the top surface of a tongue within an oral cavity. The second side has a width and a length, the smallest of which is at least 1.6 times the product thickness. The product does not include a handle and the product does not include a combination of a soft confectionery with a hard confectionery. In some embodiments the first side is smooth, and may be domed shaped and generally fit the roof of the mouth. The abrasive surface may be provided by 1) a formed, uneven surface, 2) including abrasive particles in the composition making up the second surface, or 3) a combination of a formed, uneven surface and abrasive particles. The confectionery product may be a hard confectionery, but may also be a chewing gum product.

Priority: US20050650786P Applic. Date: 2005-02-07

Inventor: STAWSKI BARBARA Z [US]; MINDAK THOMAS M [US]; SOUKUP PHILIP M [DE]; MCGREW GORDON N [US]; CLARK JAMES C [US]; HAAS MICHAEL S [US]

Title: Device for dental care and whitening

Applicant/Assignee: BIOLASE TECHNOLOGY, INC

Application No.: 11/590603   Filing Date: 30/Oct/2006

Abstract:

A dental device for exposing teeth to electromagnetic radiation includes a carrier and at least one source of electromagnetic radiation attached to the carrier and oriented so that the electromagnetic radiation is emitted from the source to a surface of a tooth. The dental device may also include a power source internally or externally disposed with respect to the carrier, and may include a circuit for controlling radiation emitted from the source. The dental device may be used for whitening teeth, and dental hygiene in general. Related methods are also disclosed.

Priority: US2003-624847 Applic. Date: 2003-07-22

Inventor: RIZOIU IOANA M [US]; KIMMEL ANDREW I [US]

Title: Processes for forming dental materials and device

Applicant/Assignee: 3M ESPE AG

Application No.: 11/593337   Filing Date: 06/Nov/2006

Abstract:

Processes for forming dental materials that include applying a first hardenable dental composition (e.g., a dental adhesive) to a surface followed by applying a second hardenable dental composition (e.g., a dental composite) to the first hardenable dental composition on the surface. The first and second hardenable dental compositions are hardened such that the second hardenable composition is substantially completely hardened prior to complete hardening of the first hardenable composition.

Priority: US2002-185431 Applic. Date: 2002-06-28

Inventor: OXMAN JOEL D [US]; CRAIG BRADLEY D [US]; KALGUTKAR RAJDEEP S [US]; PEUKER MARC [DE]; BISSINGER PETER [DE]

Title: Device for dental care and whitening

Applicant/Assignee: BIOLASE TECHNOLOGY, INC

Application No.: 11/595096   Filing Date: 08/Nov/2006

Abstract:

A dental device for exposing teeth to electromagnetic radiation includes a carrier and at least one source of electromagnetic radiation attached to the carrier and oriented so that the electromagnetic radiation is emitted from the source to a surface of a tooth. The dental device may also include a power source internally or externally disposed with respect to the carrier, and may include a circuit for controlling radiation emitted from the source. The dental device may be used for whitening teeth, and dental hygiene in general. Related methods are also disclosed.

Priority: US2003-624847 Applic. Date: 2003-07-22

Inventor: RIZOUI IOANA M [US]; KIMMEL ANDREW I [US]

Title: Device for dental care and whitening

Applicant/Assignee: BIOLASE TECHNOLOGY, INC

Application No.: 11/595398   Filing Date: 08/Nov/2006

Abstract:

A dental device for exposing teeth to electromagnetic radiation includes a carrier and at least one source of electromagnetic radiation attached to the carrier and oriented so that the electromagnetic radiation is emitted from the source to a surface of a tooth. The dental device may also include a power source internally or externally disposed with respect to the carrier, and may include a circuit for controlling radiation emitted from the source. The dental device may be used for whitening teeth, and dental hygiene in general. Related methods are also disclosed.

Priority: US2003-624847 Applic. Date: 2003-07-22

Inventor: RIZOIU IOANA M [US]; KIMMEL ANDREW I [US]

Title: Handpiece for dental or surgical use with locking mechanism

Applicant/Assignee: BIEN-AIR HOLDING S.A

Application No.: 10/558674   Filing Date: 17/Feb/2005

Abstract:

The handpiece ( 1 ) includes at the front a collet ( 10 ) arranged for strongly gripping the shank of a removable tool housed in guide bores ( 23, 25 ). The collet includes two or several arms ( 26 ) attached to an annular part ( 22 ) of the collet to grip the tool shank. Preferably, the collet arms are levers each having a support surface which is far from the jaw ( 20 ) and on which a gripping mechanism ( 17 ) exerts a force which is multiplied by the lever. The gripping mechanism includes a sliding sleeve ( 40 ) having an inner conical surface ( 44 ) which produces said force on the collet levers via balls ( 45 ). This arrangement enables a smaller gripping spring ( 42 ) to be used, or such spring to be omitted.

The balls ( 51 ) of the releasing mechanism are guided in helical slots ( 57 ) having a flexible lateral strip ( 58 ) which holds the gripping mechanism in position via a snap fit.

Priority: EP20040003520 Applic. Date: 2004-02-17; WO2005EP01612 Applic. Date: 2005-02-17

Inventor: MAITRE LUC [CH]

Title: Prepreg and its use

Applicant/Assignee: STICK TECH OY

Application No.: 10/558274   Filing Date: 21/May/2004

Abstract:

The invention relates to a prepreg comprising a base part, said base part comprising fibers and a matrix, said matrix being at least partially uncured. The prepreg is characterized in that it further comprises a surface part consisting essentially of bioactive filler material, said bioactive filler material being in particle form and at least partially and at most partially embedded in said base part. The invention also relates to a composite obtainable by curing said prepreg. The invention further relates to a mineralizing sheet for treatment of hypersensitive teeth and to the use of said prepreg and composite.

Priority: FI20030000780 Applic. Date: 2003-05-23; WO2004FI00309 Applic. Date: 2004-05-21

Inventor: VALLITTU PEKKA [FI]; YLI-URPO ANTTI [FI]; LASSILA LIPPO [FI]; NARHI TIMO [FI]; WALTIMO TUOMAS [FI]

Title: Releasable Coupling Device Between a Tool Shank and a Motor Assembly in Hand-Held Blenders

Applicant/Assignee: SAMMIC, S.L SAMMIC, S.L. BASARTE, I

Application No.: 11/460660   Filing Date: 28/Jul/2006

Abstract:

The invention discloses a fast and reliable coupling device between a tool shank and a motor assembly of a hand-held blender, which can be released by the user. The motor assembly is of the type that has a cylindrical nozzle centrally positioned on the base by which it couples to the tool shank, the outer side of which has a threaded portion, whilst the tool shank has an internally threaded nut that is complementary to the nozzle, the base of the motor assembly also including a formation that projects outwards, with a hole through which a retaining ball projects, pushed by a spring, whilst radial partitions project from the outer wall of the coupling nut of the tool shank towards the inner face of the coupling bell,

one of these partitions having on its upper edge a cup-shaped formation that is of suitable dimensions to admit and house said ball when aligned with it during the coupling operation between said tool shank and motor assembly.

Priority: ES20050001749U Applic. Date: 2005-07-28

Inventor: GARCIA JAVIER H [ES]; ZUBIZARRETA AITOR A [ES]

Title: Personal care compositions with glycerin and hydroxypropyl quaternary ammonium salts

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER CONOPCO, INC

Application No.: 11/222104   Filing Date: 08/Sep/2005

Abstract:

A personal care composition is provided formulated with glycerin and a moisturization enhancing agent which is a salt of structure AB, wherein A is a cationic charged component, B is an anionic charged component, and A has at least one quaternized nitrogen atom and at least two hydroxyl groups and a molecular weight no higher than about 400.

Priority:

Inventor: HARICHIAN BIJAN [US]; MCMANUS RICHARD L [US]; HURLEY MEGAN K [US]; MINER PHILIP E [US]; CHANDAR PREM [US]; BARROW STEPHEN R [US]

Title: 4-SUBSTITUTED 2-ARYLOXYPHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS

Applicant/Assignee: EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC

Application No.: 11/469291   Filing Date: 31/Aug/2006

Abstract:

Antimicrobial compounds, compositions and methods of treatment administering same, of 2-aryloxyphenol derivatives having heterocyclic groups or highly polar functional groups substituted at position 4 of the phenolic ring, as well as methods for their preparation and formation, wherein the compounds are generally of Formula 1.

Priority: US20050813618P Applic. Date: 2005-08-31

Inventor: HUANG LIREN [US]; CLANCY JOANNA [US]; TOMAZIC ALENKA [US]; WANG WEITONG [US]; TAYLOR CHRISTOPHER [US]; JACKSON W J [US]; LIU YUFA [US]

Title: Glucosidases, nucleic acids encoding them and methods for making and using them

Applicant/Assignee: DIVERSA CORPORATION

Application No.: 10/550155   Filing Date: 18/Mar/2004

Abstract:

The invention is directed to polypeptides having a glucosidase activity, including an alpha-glucosidase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention are used as alpha-glucosidases to catalyze the hydrolysis of starch into sugars, e.g., to convert liquefied starch to glucose. In one aspect, the polypeptides of the invention can catalyze the hydrolysis of both alpha-(1,4) and alpha-(1,6) glucose linkages. In one aspect, the polypeptides of the invention can catalyze the hydrolysis of both malto-oligosaccharides and liquefied starch.

Priority: US20030456972P Applic. Date: 2003-03-20; WO2004US08541 Applic. Date: 2004-03-18

Inventor: GRAY KEVIN [US]; GARRETT JAMES B [US]; ABOUSHADI NAHLA M [US]; KNOWLES RYAN [US]; O'DONOGHUE EILEEN [US]; WATERS ELIZABETH [US]

Title: Baffle-type grease filter for kitchen ventilators

Applicant/Assignee: FRANKLIN MACHINE PRODUCTS FRANKLIN MACHINES PRODUCTS

Application No.: 11/226140   Filing Date: 14/Sep/2005

Abstract:

A grease filter has upper and lower baffle assemblies that define tortuous paths for exhaust air flowing therethrough. A hinge connects the upper and lower baffle assemblies and permits the assemblies to pivot from a closed position to an open position. In the open position, access is provided to all surfaces of the assemblies so that they can be efficiently cleaned. A locking mechanism secures the baffle assemblies in the closed position and is located on a peripheral side of the assemblies opposite the hinge. A kitchen ventilation system and method of cleaning a grease filter are also provided.

Priority:

Inventor: AVILES JOSUE V [US]

Title: Led white light illuminator

Applicant/Assignee: INNOVATIONS IN OPTICS, INC

Application No.: 11/599721   Filing Date: 15/Nov/2006

Abstract:

The invention provides an LED lighting device and method that produces high intensity, spatially uniform, white light in the near and far fields in a reduced package size that does not significantly heat the surrounding environment, wherein the white light is produced by using a phosphor layer in conjunction with at least one LED.

Priority: US2002-334525 Applic. Date: 2002-12-30; US20010346090P Applic. Date: 2001-12-31; US20010346181P Applic. Date: 2001-12-31; US20010346182P Applic. Date: 2001-12-31; US20010346183P Applic. Date: 2001-12-31; US20010346184P Applic. Date: 2001-12-31

Inventor: BRUKILACCHIO THOMAS J [US]

Title: Methods and compositions for treating disease or injury

Applicant/Assignee: SOLUTIONS BIOMED, LLC

Application No.: 11/514722   Filing Date: 31/Aug/2006

Abstract:

The present invention is drawn to methods of treating disease or injury. In particular, the invention provides methods for treating viral infections, bacterial infections, fungal infections, and cancerous tissue. The methods include the administration of an aqueous composition that can comprise an aqueous vehicle, including water, from 0.0001 wt % to 10.0 wt % of a peroxygen, and optionally, an alcohol. Additionally, from 0.0001 ppm to 50,000 ppm by weight of a transition metal based on the aqueous vehicle content can also be present. Alternatively or additionally, the transition metal can be in the form of a colloidal transition metal, such as colloidal silver or alloy thereof.

Priority: US2006-361665 Applic. Date: 2006-02-24; US2006-361836 Applic. Date: 2006-02-24; US2006-361841 Applic. Date: 2006-02-24; US2006-361837 Applic. Date: 2006-02-24; US20050656723P Applic. Date: 2005-02-25

Inventor: TICHY DARYL J [US]; LARSON BRIAN G [US]

Title: DENTINAL COMPOSITION FOR HYPERSENSITIVE TEETH

Applicant/Assignee: BLOCK DRUG COMPANY, INC

Application No.: 11/554374   Filing Date: 30/Oct/2006

Abstract:

A composition for the treatment of sensitive teeth comprising a suitable carrier and a desensitizing amount of: a) at least one tubule blocking agent preferably a combination of two such agents

and b) a nerve desensitizing agent selected from the group consisting of at least one potassium salt at least one strontium salt and mixtures thereof wherein the tubule blocking agent deposits or swells upon the dentinal surface and/or precipitates within the dentinal tubules retaining a higher concentration of the nerve desensitizing agent at the exposed dentinal surface and within the dentinal tubules The compositions may further contain a source of physiologically acceptable fluoride ion such as stannous fluoride Also disclosed are methods of using the subject compositions in the treatment of sensitive teeth.

Priority: US2003-344074 Applic. Date: 2003-02-06; WO2001US26073 Applic. Date: 2001-08-21; US2001-850352 Applic. Date: 2001-05-07; US2000-642048 Applic. Date: 2000-08-18

Inventor: ESTRADA DAVID [US]; FITZ BENJAMIN D [US]; MACIK JAN F [US]; NAPOLITANO NEIL J [US]; SMETANA ALFRED J [US]; SYNODIS JOSEPH D [US]; TRAMA MICHAEL E [US]

Title: Film comprising therapeutic agents

Applicant/Assignee:

Application No.: 10/562633   Filing Date: 30/Jun/2004

Abstract:

The present invention is related to the composition and methods of manufacture of orally-dissolvable, edible films as a vehicle for the non-invasive administration of nitroglycerin, as well as other therapeutic agents either with or without nitroglycerin, through the mucosal tissues of the oral cavity. The films include a water soluble film-forming polymer such as pullulan. Methods for producing the films are also disclosed.

Priority: US20030484009P Applic. Date: 2003-07-01; US20030497426P Applic. Date: 2003-08-21; WO2004US21038 Applic. Date: 2004-06-30

Inventor: MAIBACH TODD [US]

Title: Antioxidant skin balm

Applicant/Assignee:

Application No.: 11/513541   Filing Date: 01/Sep/2006

Abstract:

This invention pertains to therapeutic antioxidant-lesion/abrasion/mole healing and/or removal compositions comprising therapeutically effective amount of antioxidant/free-radical fighting agents. In one embodiment, the lesion healing composition comprises (a) honey

(b) grape seed extract/proanthocyanidins powder

(c) ascorbic acid (vitamin C with rosehips)

(d) d-alpha tocopheryl acetate (natural vitamin E)

(e) soy oil

(f) purified water, grape seed oil. The therapeutic antioxidant may be used topically (on external skin) or orally (in mouth or throat areas). The antioxidant composition is sticky in texture and not suitable for applying over a wide area as a moisturizer.

Priority: US20050716754P Applic. Date: 2005-09-13

Inventor: PERRIN JUDITH L S [US]

Title: Methods and compositions to improve mouth feel

Applicant/Assignee:

Application No.: 11/225614   Filing Date: 13/Sep/2005

Abstract:

Free-flowing powdered or granular low calorie sweetener compositions containing a high intensity sweetener and a food-grade gum are provided. These compositions, when added to a solid food or beverage provide improved mouth feel without significant caloric impact. Methods of producing these sweetener compositions and kits that incorporate such compositions are also provided.

Priority:

Inventor: CATANI STEVEN J [US]; LIAO SHYHYUAN [US]; LOADES MELANIE [GB]

Title: Device for dental care and whitening

Applicant/Assignee: BIOLASE TECHNOLOGY, INC

Application No.: 11/595399   Filing Date: 08/Nov/2006

Abstract:

A dental device for exposing teeth to electromagnetic radiation includes a carrier and at least one source of electromagnetic radiation attached to the carrier and oriented so that the electromagnetic radiation is emitted from the source to a surface of a tooth. The dental device may also include a power source internally or externally disposed with respect to the carrier, and may include a circuit for controlling radiation emitted from the source. The dental device may be used for whitening teeth, and dental hygiene in general. Related methods are also disclosed.

Priority: US2003-624847 Applic. Date: 2003-07-22

Inventor: RIZOIU IOANA M [US]; KIMMEL ANDREW I [US]

Title: Dental device for preparing a tooth for a crown and for preparing the crown and a method of use

Applicant/Assignee:

Application No.: 11/269029   Filing Date: 07/Nov/2005

Abstract:

A dental device for preparing a tooth for a crown and for preparing the crown and a method of use. The dental device includes a tooth-preparation portion and a crown-preparation portion. The tooth-preparation portion prepares the tooth for the crown, thereby forming a crown-prepared-tooth, and thereafter, takes measurements of the crown-prepared tooth, thereby forming crown-prepared-tooth measurements. The crown-preparation portion is operatively connected to the tooth-preparation portion and prepares the crown for the crown-prepared tooth based upon the crown-prepared-tooth measurements received from the tooth-preparation portion.

Priority: US2005-202394 Applic. Date: 2005-09-12

Inventor: BITTAR TAWFIK [US]

Title: Methods and compositions employing 4-aminophenylacetic acid compounds

Applicant/Assignee:

Application No.: 10/594046   Filing Date: 22/Mar/2005

Abstract:

The invention provides compositions comprising 4-APAA compounds and methods for treating disorders involving inflammation of the digestive system and/or mucosal tissues, such as inflammatory bowel disease. The methods and compositions of the invention also include combinations of 4-APAA compounds and 5-ASA compounds for treatment of such disorders.

Priority: US20040555551P Applic. Date: 2004-03-23; WO2005US09325 Applic. Date: 2005-03-22

Inventor: EKWURIBE NNOCHIRI N [US]; LIDDLE RODGER [US]

Title: Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents

Applicant/Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

Application No.: 11/516692   Filing Date: 07/Sep/2006

Abstract:

The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q-(Y1)p-(U)p-(Y2)p-A: wherein Q represents an aminoquinoline, (Y1)p(U)p-(Y2)p'' is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.

Priority: FR20040008441 Applic. Date: 2004-07-30; US2004-019450 Applic. Date: 2004-12-23; WO2005FR01937 Applic. Date: 2005-07-26

Inventor: SANCHEZ MURIEL [FR]; MEUNIER BERNARD [FR]

Title: Inhibitors of p38

Applicant/Assignee: VERTEX PHARMACEUTICALS INCORPORATED

Application No.: 11/430512   Filing Date: 08/May/2006

Abstract:

The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.

Priority: US2003-638126 Applic. Date: 2003-08-08; US2000-746722 Applic. Date: 2000-12-21; WO1999US10291 Applic. Date: 1999-05-11; US19980085053P Applic. Date: 1998-05-11; US19990127626P Applic. Date: 1999-04-01; US19990129099P Applic. Date: 1999-04-13

Inventor: SALITURO FRANCESCO [US]; GALULLO VINCENT [US]; BELLON STEVEN [US]; BEMIS GUY [US]; COCHRAN JOHN [US]

Title: Curable silicone impression materials with high tear strength and low consistency

Applicant/Assignee:

Application No.: 10/554989   Filing Date: 07/May/2004

Abstract:

The invention relates to curable silicone compositions which contain silane based crosslinkers and a mixture of different organopolysiloxanes. The compositions are particularly suitable as curable impression materials in dental applications.

Priority: EP20030010519 Applic. Date: 2003-05-09; WO2004EP04861 Applic. Date: 2004-05-07

Inventor: ZECH JOACHIM W [DE]; STRAUSS FRANZISKA [DE]; HOFFMANN HENNING [DE]; BISSINGER PETER [DE]; STEIGER WOLF [DE]

Title:

Applicant/Assignee: JON CHENG, CECIL M. ALBAO

Application No.: 11/399331   Filing Date: 07/Apr/2006

Abstract:

The basic reaction steps in the process during the treatment of toxic & hazardous, infectious, bio-hazardous, metallic and non-metallic residuals and light-slight radiation contaminated leftovers/residuals are: sterilization, remediation, neutralization, oxidation in combination with a three step polymerization, supported through mechanical material destruction mechanism for volume reduction and reagent attachable surface increase. The entire process operates on low temperature and energy, supported through chemical, bio-chemical, physical-chemical and electro-chemical reactions and mechanisms. The whole operation is considered as leftover, emission, odor and discharge free non burn combustion and roasting technology. The process ending is the final conversion and if descried, the homogenization of the formerly unwanted residuals, which are present after the process with an inert like characteristic without the origin of the material can be recognized, into a secondary raw material for further reuse for different products and applications in a human and environmentally safe way.

Priority: US20050669345P Applic. Date: 2005-04-08

Inventor: KREMNITZ HARALD W [PH]

Title: Apparatus for sanitizing bottles and dispensing purified water into the bottles

Applicant/Assignee:

Application No.: 11/205315   Filing Date: 17/Aug/2005

Abstract:

A stand for dispensing purified water into a supply bottle has both a dispensing nozzle on the stand with a customer actuated switch supply of the water through the spout and a sanitizing system in the stand for pre-sanitizing the bottle prior to filling at the point. The sanitizing system includes a nozzle for injecting liquid into the bottle projecting through a drain opening with at least one customer actuated switch for supply of liquid to said at least one nozzle. The nozzle is located underneath the base surface of the filling station such that the bottle is inverted and its neck inserted through a hole into the base onto a switch at the drain to ensure the bottle is in place before the injection nozzle is operated.

Priority:

Inventor: HOFER MICHAEL I [CA]

Title: Tree smoke detection system and method of using same

Applicant/Assignee:

Application No.: 11/230678   Filing Date: 20/Sep/2005

Abstract:

A tree smoke detection system and method which includes a conically shaped smoke collector housing having an interior wall extending between a wide entrance mouth opening and a narrow exit vent opening and a smoke detection device mounted to the interior wall to position the smoke detection device facing and adjacent to an imaginary center line passing through the wide entrance mouth opening and the narrow exit vent opening to facilitate detecting smoke flow along the imaginary center line.

Priority: US20050714521P Applic. Date: 2005-02-01

Inventor: KISNER ALLEN P [US]; KISNER JANET L [US]

Title: Biochemical assay detection using a fiber optic exciter

Applicant/Assignee: BIO-RAD LABORATORIES, INC. A CORPORATION OF THE STATE OF DELAWARE BIO-RAD LABORATORIES, INC

Application No.: 11/521677   Filing Date: 14/Sep/2006

Abstract:

Biochemical assays of samples in receptacles, in gels, in blots, in arrays and the like, and that utilize excitation and light emission as labels for detection are enhanced by an illumination and detection system that supplies excitation light through an optical fiber that transmits excitation light from an excitation light source to the sample. Emission light produced by the excitation is then collected by a lens and converted to a signal that is compiled by conventional software for analysis. The optical fiber transfixes (passes through) the lens via a slot or other opening and is preferably offset from the center of the lens. The optical fiber and collecting lens can either be on the same side of the sample or on opposite sides, i.e., one above and the other below.

The optical fiber and the light collecting lens are arranged such that the direction of travel of the excitation light and the direction along which the emission light is collected are not coaxial, and preferably both are at an acute angle to the axis normal to the mouth of the receptacle. Illumination systems are also disclosed in which a ultraviolet, visible, or near-infrared light source is optically coupled to an optical fiber.

Priority: US2002-252023 Applic. Date: 2002-09-19; US20010325855P Applic. Date: 2001-09-27; US20010325876P Applic. Date: 2001-09-27

Inventor: HILLENDAHL JAMES W [US]; WALDBESER DAVID E [US]

Title: Compositions and Methods for Suppressing Fibrocytes and for Detecting Fibrocyte Differentiation

Applicant/Assignee: WILLIAM MARSH RICE UNIVERSITY

Application No.: 11/535636   Filing Date: 27/Sep/2006

Abstract:

The present invention relates to the ability of SAP to suppress fibrocytes. It also relates to the ability of IL-12, laminin-1, cross-linked IgG and IgG aggregates to suppress fibrocytes. Methods and compositions for suppressing fibrocytes using these proteins are provided. These methods are useful in a variety of applications including treatment and prevention of fibrosing diseases such as scleroderma, pulmonary fibrosis and asthma. Finally, the invention includes assays for detecting the ability of various agents to modulate differentiation into fibrocytes. Such assays may also be used to diagnose scleroderma, pulmonary fibrosis, or other fibrosing diseases.

Priority: US2005-158966 Applic. Date: 2005-06-22; WO2003US40957 Applic. Date: 2003-12-22; US20020436046P Applic. Date: 2002-12-23; US20020436027P Applic. Date: 2002-12-23; US20030515776P Applic. Date: 2003-10-30; US20030519467P Applic. Date: 2003-11-12; US20030525175P Applic. Date: 2003-11-26

Inventor: GOMER RICHARD [US]; PILLING DARRELL [US]

Title: Method and composition for preventing tooth hypersensitivity when using passive bleaching agents

Applicant/Assignee:

Application No.: 11/527276   Filing Date: 26/Sep/2006

Abstract:

Dental bleaching compositions, for example in the form of liquids, gels, creams, pastes and ointments, comprising a peroxide releasing compound and from 1% to 35% by weight of a potassium-containing compound such as potassium nitrate, wherein the potassium nitrate is present in a safe and effective amount to prevent tooth hypersensitivity in the patient during the bleaching process. The potassium nitrate contemplated by the invention is compatible with peroxide yielding bleaching compounds such as peroxide, carbamide peroxide, calcium peroxide, zinc peroxide, magnesium peroxide and sodium perborate. Potassium nitrate is complimentary and synergistic with the peroxide bleaching agents contemplated by the invention and enhances the release of oxygen to the tooth enamel. Also contemplated are methods of bleaching teeth comprising application of the dental bleaching compositions of the invention.

Priority: US2005-230404 Applic. Date: 2005-09-20

Inventor: HODOSH MILTON [US]

Title: Compositions effective in altering the perception of malodor

Applicant/Assignee:

Application No.: 10/579842   Filing Date: 15/Nov/2004

Abstract:

A method of modifying perception of a malodor, such as the stench associated with putrefying flesh, by selectively affecting specific olfactory receptors in an individual is disclosed. Disclosed are articles of manufacture and especially innovative compositions effective in implementing the method of the present invention including at least three plant extracts.

Priority: US20030520319P Applic. Date: 2003-11-17; US20030526600P Applic. Date: 2003-12-04; WO2004IL01047 Applic. Date: 2004-11-15

Inventor: PINNEY VIRGINIA R [US]

Title: Dental kit and method for retracting sulcus

Applicant/Assignee:

Application No.: 11/546754   Filing Date: 10/Oct/2006

Abstract:

Sulcus is retracted from teeth prior to perfroming a dental procedure on the teeth by applying an expandible curable silicone compound to the surface of the teeth and preventing the silicone compound from exanding in a direction away from the suface of the teeth, thereby forcing the silicone to expand against the sulcus and forcing retraction of the sulcus from contact with the teeth.

Priority: EP20030006052 Applic. Date: 2003-03-19; WO2003CH00798 Applic. Date: 2003-12-02

Inventor: LUBBERS DIERK [CH]; LAMPL STEPHAN [CH]; KOLLEFRATH RALF [CH]

Title: Composite paste for dental prostheses

Applicant/Assignee: DANVILLE MATERIALS, INC

Application No.: 11/520450   Filing Date: 12/Sep/2006

Abstract:

In general, the invention comprises a composite paste ("try-in paste") made with the same or similar components in similar proportions as a veneer cement except part or all of the initiation system is removed or reduced to cause it to have an extended working time under the type of ambient light conditions expected during the trial placement of the veneer. Preferably, the imitator is decreased by not eliminated from the try-in paste. The invention can be presented in the form of a kit containing one or more shades of veneer cement with corresponding shades of try-in paste.

Priority: US20050717215P Applic. Date: 2005-09-14

Inventor: DORSMAN GREGORY J [US]; BERTOLOTTI RAYMOND L [US]

Title: Activating endodontic points and dental tools for initiating polymerization of dental compositions

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/232062   Filing Date: 21/Sep/2005

Abstract:

Activating endodontic points and dental tools are sized and configured to be placed in the root canal of a tooth. The activating endodontic points or dental tools are coated or impregnated with a curing agent that initiates or accelerates polymerization of a sealer or filling composition when placed in contact with the sealer or filler material. Curing agents can include amines that can destabilize a peroxide in the sealer or filler material to initiate or accelerate polymerization. Kits are also disclosed that include a plurality of endodontic points or dental tools that have different concentrations of curing agent coated on or impregnated within the endodontic points or dental tools such that the endodontic points or dental tools have different cure times.

In another kit, a plurality of curing agent compositions are provided for dipping a substrate to coat or impregnate substrates having different concentrations of curing agent.

Priority:

Inventor: WAGNER JEFF A [US]; JESSOP NEIL T [US]; FISCHER-JESSOP JALEENA [US]

Title: Dental examination and treatment tool

Applicant/Assignee:

Application No.: 11/523365   Filing Date: 19/Sep/2006

Abstract:

The invention relates to a Dental examination or treatment tool. the tool comprises at least one lumen in which at least one imaging catheter is or can be accommodated for recording image data of an examination or treatment area.

Priority: DE200510044889 Applic. Date: 2005-09-20; US2005-058655 Applic. Date: 2005-02-15

Inventor: MASCHKE MICHAEL [DE]

Title: Compositions, Kits and Methods for Initiating or Accelerating Curing of Endodontic Filler or Sealer Compositions Placed on a Root Canal

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/530787   Filing Date: 11/Sep/2006

Abstract:

Activating endodontic points and dental tools are sized and configured to be placed in the root canal of a tooth. The activating endodontic points or dental tools are coated or impregnated with a curing agent that initiates or accelerates polymerization of a sealer or filler composition when placed in contact with the sealer or filler material. Curing agents can include amines that can destabilize a peroxide in the sealer or filler material to initiate or accelerate polymerization, or they may comprise the peroxide. An implement can be dipped in a concentrated curing composition just prior to inserting the implement into a root canal to contact the filler or sealer composition. Kits may include a plurality of curing agent compositions having different concentrations and/or amounts of curing agent. Kits may also include a curable resin material that includes a first part of a multi-part curing system and a curing composition that includes, as curing agent a complementary part of the curing system.

Priority: US2005-232062 Applic. Date: 2005-09-21

Inventor: TUTTLE RICHARD D [US]; WAGNER JEFF A [US]; JESSOP NEIL T [US]; FISCHER-JESSOP JALEENA [US]

Title: Detecting foot-and-mouth disease virus

Applicant/Assignee:

Application No.: 11/233245   Filing Date: 21/Sep/2005

Abstract:

This document relates to methods and materials involved in determining whether or not an animal contains a foot-and-mouth disease virus. For example, nucleic acid primer pairs, combinations of nucleic acid primer pairs, nucleic acid arrays (e.g., diagnostic cards) containing nucleic acid primer pairs or combinations of nucleic acid primer pairs, methods for making such nucleic acid arrays, and methods for diagnosing animals infected with a foot-and-mouth disease virus are provided.

Priority:

Inventor: ENGELHARD ERIC K [US]

Title: Compositions and Methods for Suppressing Fibrocytes

Applicant/Assignee: WILLIAM MARSH RICE UNIVERSITY

Application No.: 11/535649   Filing Date: 27/Sep/2006

Abstract:

The present invention relates to the ability of anti-FcgammaR antibodies to suppress fibrocytes. Methods and compositions for suppressing fibrocytes are provided. These methods are useful in a variety of applications including treatment and prevention of conditions resulting from fibrosis in the liver, kidney, lung, heart and pericardium, eye, skin, mouth, pancreas, gastrointestinal tract, brain, breast, bone marrow, bone, genitourinary system, a tumor, or a wound.

Priority: WO2006US05229 Applic. Date: 2006-02-15; WO2003US40957 Applic. Date: 2003-12-22; US20020436046P Applic. Date: 2002-12-23; US20020436027P Applic. Date: 2002-12-23; US20030515776P Applic. Date: 2003-10-30; US20030519467P Applic. Date: 2003-11-12; US20030525175P Applic. Date: 2003-11-26

Inventor: GOMER RICHARD [US]; PILLING DARRELL [US]

Title: Topical administration permitting prolonged exposure of target cells to therapeutic and prophylactic nucleic acids

Applicant/Assignee: INTROGEN THERAPEUTICS, INC

Application No.: 11/336664   Filing Date: 20/Jan/2006

Abstract:

Compositions and methods for preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include a nucleic acid comprised in a solid or semi-solid formation or in a transdermal or transcutaneous delivery device are disclosed. Also disclosed are compositions of a nucleic acid capable of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include an adhesive. Compositions of a nucleic acid capable of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that include a nucleic acid uptake enhancer are also disclosed. Methods of preventing or inhibiting the growth of a hyperproliferative lesion in a subject that involve these therapeutic compositions and devices are also disclosed.

Priority: US20050645826P Applic. Date: 2005-01-21; US20050692481P Applic. Date: 2005-06-21

Inventor: CLARKE PETER [US]; CHADA SUNIL [US]; MENANDER KERSTIN [US]; SOBOL ROBERT E [US]; ZHANG SHUYUAN [US]

Title: Curable compositions containing dithiane monomers

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/229903   Filing Date: 19/Sep/2005

Abstract:

The invention features compositions comprising at least one monomer that comprises a cyclic dithiane moiety attached to a (meth)acryloyl moiety. The composition may optionally contain additional polymerizable compounds, such as ethylenically unsaturated compounds, that are typically used in dental compositions.

Priority:

Inventor: LEWANDOWSKI KEVIN M [US]; ABUELYAMAN AHMED S [US]; PLAUT DAVID J [US]; GADDAM BABU N [US]

Title: Methylene blue

Applicant/Assignee: STRAUMANN HOLDING AG

Application No.: 11/521971   Filing Date: 15/Sep/2006

Abstract:

Composition comprising a polymerizable compound with at least one conjugated unsaturated group and methylene blue to prevent premature polymerization of the polymerizable compound. The methylene blue is present in a concentration of 10 to 5000 ppm.

Priority: EP20040014072 Applic. Date: 2004-06-16; EP20050020181 Applic. Date: 2005-09-16; WO2005EP04977 Applic. Date: 2005-05-09

Inventor: MOLENBERG AALDERT [CH]

Title: Cylindrical applicator for dispensing cosmetic compositions

Applicant/Assignee:

Application No.: 10/572863   Filing Date: 20/Apr/2004

Abstract:

Cylindrical applicator for dispensing cosmetic compositions in the form of liquid, cream, gel or other, onto the human skin. The invention comprises an applicator in the form of a cylinder ( 1 ) of rigid material, encased by pressure inside a seat ( 2 ) of resilient material, said seat consists of two semicircular guides ( 3 ), joined by two support circles ( 4 ), and two inferior braces ( 5 ) that define the distribution opening ( 6 ), being said cylinder ( 1 ) free to roll. The present invention is the main part of the head section of various packages. Said cylinder ( 1 ) is coated by the cosmetic product when the container is turned upside-down, and rolled against the skin, applying the product uniformly. When pressed down by internal elements of the cap, the cylinder ( 1 ) seal the distribution opening ( 6 ). With a larger area of application, the present invention is used to apply a large number of cosmetic products to extensive areas, like the face or the body.

Priority: BR20030005111 Applic. Date: 2003-09-23; WO2004BR00056 Applic. Date: 2004-04-20

Inventor: DORIA ANTONIO S S [BR]

Title: Live bacterium preparation containing lactic acid bacterium as active ingredient and food containing lactic acid bacterium

Applicant/Assignee: FRENTE INTERNATIONAL CO., LTD

Application No.: 10/508340   Filing Date: 29/Mar/2002

Abstract:

Disclosed is a live bacterium preparation or food containing a lactic acid bacterium comprising a lactic acid bacterium, Lactobacillus salivarius, as an active ingredient. There is provided a live bacterium preparation and food containing a lactic acid bacterium that can prevent onset, recurrence and exacerbation of periodontal disease and/or dental caries caused by periodontopathic bacteria and cariogenic bacteria and can prevent generation of halitosis and maintain pH of saliva at a physiologically normal level by normalizing intraoral microflora.

Priority: WO2002JP03177 Applic. Date: 2002-03-29

Inventor: KOGA YASUHIRO [JP]

Title: Bioactive Material Delivery Systems Comprising Sol-Gel Compositions

Applicant/Assignee: MEDLOGICS DEVICE CORPORATION

Application No.: 11/463237   Filing Date: 08/Aug/2006

Abstract:

Implantable medical devices employing a sol-gel composition coatings that functions as a bioactive material reservoir, and the use of sol-gel composition coatings for improved adhesion of organic and inorganic substrates are disclosed.

Priority: WO2004US40270 Applic. Date: 2004-12-01; US20060764941P Applic. Date: 2006-02-02; US20040546091P Applic. Date: 2004-02-18

Inventor: PANTELIDIS DIMITRIOS [US]; BRAVMAN JOHN C [US]; ROTHBARD JONATHAN [US]; KLEIN RICHARD L [US]

Title: Topical anesthetic for dental procedures

Applicant/Assignee:

Application No.: 11/238748   Filing Date: 29/Sep/2005

Abstract:

A topical anesthetic for dental procedures is provided containing about 3 wt % to 10 wt % tetracaine in a vehicle suitable for administration to the oral mucosa. The vehicle for transporting the tetracaine includes a water soluble mucoadhesive or a combination of mucoadhesives such as a high molecular weight poly(ethylene oxide) homopolymer and a cellulose polymer. The vehicle may additionally include a penetration enhancer such as propylene glycol. The tetracaine is ground into a powder and is suspended in a plasticized hydrocarbon gel which completes the vehicle.

Priority:

Inventor: WICKENHAUSER ALAN J [US]; PEIPERT STEPHEN E [US]

Title: Dispensing syringe having multiple barrels for discharging a dental composition

Applicant/Assignee: DENTSPLY RESEARCH AND DEVELOPMENT CORP

Application No.: 11/238374   Filing Date: 29/Sep/2005

Abstract:

A dispensing syringe for dispensing a multi-component dental composition, preferably a two component composition, is provided. The syringe includes a syringe body with multiple elongated barrels for storing the components of the composition

a threaded plunger rod assembly

and a rotatable, threaded connector knob. Preferably, the syringe body has a double-barrel structure and the plunger rod assembly includes two plunger rods that slide within the barrels. The threaded knob has a through-bore with a continuous internal thread for engaging the outer threads of the first and second plunger rods. A dental practitioner manually rotates the knob to displace the first and second plunger rods and discharge the components. The dispensing syringe may further include a dispensing tip containing a static mixing element for mixing the components and dispensing the mixed composition.

Priority:

Inventor: PIERSON PAUL R [US]

Title: Method for creating a temporary dental crown

Applicant/Assignee:

Application No.: 11/527006   Filing Date: 26/Sep/2006

Abstract:

A method for making a temporary dental crown is disclosed. The temporary crown material that is used includes an astringent, which forms part of the material itself, to control bleeding in the gums of the patient whereby the steps involved in the procedure are simplified and minimal time is required to perform the procedure.

Priority: US20050720644P Applic. Date: 2005-09-26

Inventor: JAGHAB JEFFREY [US]

Title: Histone hyperacetylating agents for promoting wound healing and preventing scar formation

Applicant/Assignee:

Application No.: 10/843025   Filing Date: 10/May/2004

Abstract:

A method for promoting wound healing and preventing scar formation in a variety of wounds in skin, mucosa, and cornea. The method comprises administering a therapeutically effective amount of a histone deacetylase inhibitor or a hyperacetylating agent. The histone deacetylase inhibitor or hyperacetylating agent is capable of stimulating multiple cytokines/growth factors in the early phase of wound healing, and suppressing fibrogenic cytokines/growth factors in the late phase of tissue remodeling in the wound site, and is useful in promoting epithelial cell re-growth and reducing excessive collagen accumulation, which results in rapid wound closure with reduced scaring.

Priority: US2002-205738 Applic. Date: 2002-07-25

Inventor: CHUNG YIH-LIN [TW]

Title: DENTAL PASTE GLASS IONOMER CEMENT COMPOSITION

Applicant/Assignee: GC CORPORATION

Application No.: 11/532718   Filing Date: 18/Sep/2006

Abstract:

To give high mechanical strength, particularly compression strength, and excellent operationality in a two-paste system, a dental paste glass ionomer cement composition comprises a first paste comprising an alpha-beta unsaturated carboxylic acid polymer, a filler that is not reacted with the alpha-beta unsaturated carboxylic acid polymer and is not in a monodisperse state in water, a silica aqueous sol containing colloidal silica having an average particle diameter of 1 to 100 nm dispersed in a monodisperse state in water to an SiO2 concentration of 1 to 50% by weight, and water, in prescribed amounts respectively, and a second paste containing fluoroalumino silicate glass powder in a prescribed amount, where the second paste sometimes contains a thickening agent comprising a water soluble polymer material and water, or a polymerizable monomer having no acid group.

Priority: JP20050280327 Applic. Date: 2005-09-27

Inventor: NOGUCHI TSUYOSHI [JP]; KATO KATSUHITO [JP]; NAKASEKO HISASHI [JP]

Title: Bag-filling packaging machine

Applicant/Assignee: TOYO JIDOKI CO., LTD

Application No.: 11/542516   Filing Date: 02/Oct/2006

Abstract:

A bag-filling packaging machine in which supplied bags 1 are gripped by pairs of grippers 2 disposed on the periphery of an intermittently turning round table 3, and the bags, at stopping positions, are successively subjected to prescribed packaging operations with the gas inside the bags being replaced during that process, wherein a pair of guide members 15 and 16 for keeping the bag mouth opened is provided on the table 3 in correspondence with each of the gripper pair, and guide members 15 and 16 are connected to an inactive gas supply source and have gas blow-out ports at the tip ends that are inserted inside the bags, thus allowing the guide members 15 and 16 to not only keep the bag mouth opened but also function as gas blow-in nozzles.

Priority: JP20050290518 Applic. Date: 2005-10-03; JP20060010891 Applic. Date: 2006-01-19

Inventor: KOGA SHOICHI [JP]; KAWAMURA KENJI [JP]

Title: Valve for sterile sampling of a liquid sample from a container

Applicant/Assignee: KEOFITT A/S

Application No.: 10/595516   Filing Date: 28/Oct/2004

Abstract:

A valve for sterile sampling of a liquid sample from a container comprises a valve body ( 1 ) with a. valve chamber ( 2 ). The valve is moreover provided with a sample inlet ( 6 ) in the valve chamber ( 2 ), a first valve seat ( 7 ), a first valve plug ( 5 a) for closing the sample inlet ( 6 ) through abutment against a first valve seat ( 7 ), an outlet ( 8 ) from the valve chamber ( 2 ), a cleaning inlet ( 9 ) in the valve chamber ( 2 ) for disinfection fluid, a second valve seat ( 10 ) and a second valve plug ( 5 b). The outlet ( 8 ) is positioned between the two valve seats ( 7, 10 ), and the second valve seat ( 10 ) and the second valve plug ( 5 b) are positioned in such a manner that the second valve plug ( 5 b) through abutment against the second valve seat ( 10 ) cuts off the inflow of disinfection fluid in an area ( 2 b) of the valve chamber ( 2 ) at the sample inlet ( 6 ).

Priority: DK20030001586 Applic. Date: 2003-10-28; WO2004DK00743 Applic. Date: 2004-10-28

Inventor: SALOMON HENRIK L [DK]

Title: Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy

Applicant/Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION

Application No.: 11/471047   Filing Date: 19/Jun/2006

Abstract:

Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages and formulations of topical vasoconstrictors are provided. Methods for the use of such compositions are also provided.

Priority: US20050691571P Applic. Date: 2005-06-17

Inventor: FAHL WILLIAM E [US]; RUOHO ARNOLD E [US]; MEHTA MINESH [US]

Title: Silver- and zinc- containing body care agent

Applicant/Assignee: BIO-GATE AG

Application No.: 10/569709   Filing Date: 26/Aug/2004

Abstract:

The invention relates to a body care agent containing metal particles which release zinc and silver ions in said body care agent by contacting body liquid or body humidity and whose metallic silver content at least equal or greater than 99% (m/m).

Priority: DE20031040276 Applic. Date: 2003-08-29; WO2004EP09534 Applic. Date: 2004-08-26

Inventor: BERCHERT THORSTEN [DE]; WAGENER MICHAEL [DE]; STEINRUECKE PETER [DE]

Title: Child discipline composition and method

Applicant/Assignee:

Application No.: 11/241055   Filing Date: 30/Sep/2005

Abstract:

A composition for substantially deterring unwanted behaviors in children is provided. The composition comprises water, goldenseal tincture, and apple cider vinegar in an effective amount. The composition is sprayed toward the mouth of the child after the child engages in the unwanted behavior. The composition may be sprayed from an aerosol can, sprayer, or the like.

Priority:

Inventor: SCHOENBORN SHAUNA M [US]

Title: Blank and intermediate article for the production of a dental prosthetic item and process for the production thereof

Applicant/Assignee:

Application No.: 10/571257   Filing Date: 13/Sep/2004

Abstract:

The invention relates to a blank for the production of a dental prosthesis. The blank has a frame structure with open-pored cavities. Other objects of the invention are a dental prosthesis produced from a blank and a method for the production of a blank and/or dental prosthesis.

Priority: DE20031042231 Applic. Date: 2003-09-11; WO2004EP52147 Applic. Date: 2004-09-13

Inventor: SALIGER GUNTER [DE]; PFEIFER JOACHIM [DE]

Title: Dental material for attaching a cast metal structure to a metal coping in the preparation or repair of a dental restoration

Applicant/Assignee:

Application No.: 11/243270   Filing Date: 04/Oct/2005

Abstract:

A dental material composition for attaching a metal structure to a dental coping in the preparation or repair of a dental restoration which includes a component of high-fusing temperature metal particles in a range of between 1-10 weight percent, a component of low fusing temperature metal particles having a melting temperature below the melting temperature of the high-fusing particles in excess of at least 90 weight percent and preferably above about 95 weight percent of the total composition with the low fusing temperature metal particles composed primarily of gold, a small measure of borate fluxes in a range of between 0.1 to 2.0% by weight of the total composition and a volatile binder.

Priority:

Inventor: SHOHER ITZHAK [IL]; WHITEMAN AHARON [IL]

Title: Epoxy based oil free root canal sealer

Applicant/Assignee: ESSENTIAL DENTAL SYSTEMS, INC

Application No.: 11/528096   Filing Date: 27/Sep/2006

Abstract:

Epoxy-based root canal dental compositions and root canal sealing dental filling systems including an epoxy-based root canal dental composition are described. The dental compositions include an epoxy polymer comprising a plurality of amide monomers, a plurality of diepoxide monomers and at least one fumed silica. In a preferred embodiment, the dental composition contains substantially no silicone or mineral oil.

Priority: US20050721309P Applic. Date: 2005-09-28

Inventor: MUSIKANT BARRY L [US]; DEUTSCH ALLAN S [US]; RASIMICK BRIAN [US]; GU QUAN [US]

Title: Thieno-pyridinone derivatives as kinase inhibitors

Applicant/Assignee: CELLTECH R&D LIMITED UCB PHARMA S.A

Application No.: 10/576731   Filing Date: 22/Oct/2004

Abstract:

A series of thieno[2,3-b]pyridin-6(7H)-one derivatives, substituted in the 3-position by an arylcarbonyl or heteroaryl-carbonyl moiety, being inhibitors of p38 MAP kinase, are accordingly of use in medicine, for example in the treatment and/or prevention of immune or inflammatory disorders.

Priority: GB20030024902 Applic. Date: 2003-10-24; GB20030029490 Applic. Date: 2003-12-19; GB20040002918 Applic. Date: 2004-02-10; GB20040016934 Applic. Date: 2004-07-29; WO2004GB04490 Applic. Date: 2004-10-22

Inventor: ALEXANDER RIKKI P [GB]

Title: Fused heterocyclic compounds useful as kinase modulators

Applicant/Assignee: BRISTOL-MYERS SQUIBB COMPANY

Application No.: 11/524996   Filing Date: 21/Sep/2006

Abstract:

Compounds having the formula (1), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, are usefuil as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, Z is N or CR3, and R1, R2, R3, X and Y are as defined herein.

Priority: US20050719519P Applic. Date: 2005-09-22

Inventor: VACCARO WAYNE [US]; CHEN ZHONG [US]; DODD DHARMPAL S [US]; HUYNH TRAM N [US]; LIN JAMES [US]; LIU CHUNJIAN [US]; MUSSARI CHRISTOPHER P [US]; TOKARSKI JOHN [US]; TORTOLANI DAVID R [US]; WROBLESKI STEPHEN T [US]

Title: (Meth) acrylic ester compound and use thereof

Applicant/Assignee: MITSUI CHEMICALS, INC

Application No.: 10/557882   Filing Date: 21/May/2004

Abstract:

A (meth)acrylic ester compound represented by the general formula (1) and a dental material containing the compound, wherein, in the formula, R11 represents a divalent aromatic group

R12 represents a hydrogen atom or a methyl group

R13 represents an aryl group

R14 represents a hydrogen atom or a methyl group

and X11, represents an oxygen atom or a sulfur atom. A polymerizable composition containing the (meth)acrylic ester compound and an optical part obtained by polymerizing the polymerizable composition are also provided. The cured composition can provide advantageous physical and optical properties.

Priority: JP20030145616 Applic. Date: 2003-05-23; JP20030284921 Applic. Date: 2003-08-01; JP20030356465 Applic. Date: 2003-10-16; WO2004JP07327 Applic. Date: 2004-05-21

Inventor: OTSUJI ATSUO [JP]; TAKAGI MASATOSHI [JP]; HIGUCHI CHOJIRO [JP]; NAGATOMO AKINORI [JP]; SUESUGI KOUJI [JP]; TOIDA TETSUYA [JP]; HONDA NARIMICHI [JP]

Title: Intraoral mandibular advancement device for treatment of sleep disorders, including snoring, obstructive sleep apnea, and gastroesophageal reflux disease and method for delivering the same

Applicant/Assignee:

Application No.: 11/416991   Filing Date: 03/May/2006

Abstract:

An intraoral mandibular advancement device to treat problems associated with sleep disorders in a user having an obstructed airway, the disorders including, without limitation, snoring, obstructive sleep apnea, gastroesophageal reflux disease and/or bruxism having a main body for attachment to the user's mouth and having a central portion

a protrusive element distending from the central portion of the main body such that when worn by the user the element causes mandibular advancement sufficient to expand the oropharangeal space and reduce the obstruction

and a retainer extending from the main body for retention of the device in the user's mouth when worn during the user's sleep state. The main body is either complimentary with the user's palate and lingual surfaces of the maxillary teeth, rests against the palate and lingual surface of the user's anterior mandibular teeth when the device is inserted in the user's mouth, or customized to rest against two, four or six of the user's front teeth. The protrusive element is of distension between 5 and 15 mm, and optimally 10 mm downwardly from the main body, and can be adjusted such that the advancement ranges between 1.0 and 7.0 mm, and having an initial treatment protrusion of 3.0 to 4.0 mm, or 1/2 of the total potential maximum protrusive range. A method for diagnosis and delivery of the device is also shown.

Priority: US20050724597P Applic. Date: 2005-10-07

Inventor: LAMBERG STEVEN B [US]

Title: Spill-proof smoking implement

Applicant/Assignee:

Application No.: 11/543802   Filing Date: 06/Oct/2006

Abstract:

A smoking implement includes a cylindrical container having a sufficient volume of water to act as a filter for ash, resin and unburnt tobacco particles. The container has a mouthpiece at its top end through which smoke can be inhaled. An elongate pipe or stem extends through a side wall of the container. One end of the pipe is adapted to allow smoke to bubble up through the water in the container when in its upright position

the other end of the pipe has a receptacle or cone in which a quantity of tobacco may be burnt. A hollow tapered extension piece is provided in connection with the mouthpiece, and extends some distance into the container. The extension piece ends in a distal opening of reduced size relative to the mouthpiece, and is fitted with a valve member. In the event that the container is knocked over from its upright position the distal opening will be substantially above the water level so that water is inhibited from spilling out of the container through the mouthpiece.

Priority: AU20050220208 Applic. Date: 2005-10-06

Inventor: RUSSON JOHN [AU]

Title: Oral hygiene apparatus

Applicant/Assignee:

Application No.: 11/514398   Filing Date: 23/Aug/2006

Abstract:

A frame facilitating dental floss-based tooth cleaning and oral and vaporous administration of medication has two pieces, each with surfaces adapted for facing contacting securement one to another, with plurality of male and female members located on the facing surfaces for mating engagement as the pieces are assembled to form the frame, with the male members being adapted to puncture, if needed, and to retain a medication impregnated web in place, as the male members enter the female members with the web is positioned therebetween.

Priority: US2002-215349 Applic. Date: 2002-08-08

Inventor: SAMPSON MARK A [US]

Title: Micro powered gas-forming device

Applicant/Assignee: KIMBERLY-CLARK WORLDWIDE, INC

Application No.: 11/247917   Filing Date: 11/Oct/2005

Abstract:

A gas dispenser includes a reservoir for holding a liquid, and a chamber in communication with the reservoir. The chamber receives the liquid, and a micro power source generates energy for conversion of the liquid disposed in the chamber. A nozzle defining an orifice in selective communication with the chamber. The nozzle is used to release the converted liquid from the chamber through the orifice.

Priority:

Inventor: LINDSAY JEFFREY D [US]; CHEN FUNG-JOU [US]; RIPPL CARL G [US]; TYRRELL DAVID J [US]; ELLEFSON KIM [US]; MEYER MARY J [US]

Title: Vial for test strips

Applicant/Assignee: AGAMATRIX, INC

Application No.: 11/249093   Filing Date: 11/Oct/2005

Abstract:

A diagnostic test strip vial has a container, a lid, and a plurality of diagnostic test strips. The container has a generally annular wall that terminates at a base and at an open mouth at an end that is opposite the base. The annular wall is cut at an oblique angle creating a wall that has a high side and a low side at the open mouth. The low side of the annular wall of the container is shorter in length than a diagnostic test strip that enclosed in the vial when the lid is closed with the container.

Priority:

Inventor: BOOZER BRAD [US]; FLAHERTY JOSEPH [US]; GOLNIK TIMOTHY [US]; HARDING IAN [US]; IYENGAR SRIDHAR G [US]

Title: Dental x-ray radiation protection device

Applicant/Assignee: MS. SAEIDEH MOUSAVI YEGANEH

Application No.: 11/512147   Filing Date: 30/Aug/2006

Abstract:

A dental x-ray radiation protection device/system reduces radiation exposure to patient(s) and the surrounding environment around patient(s) in dental clinics during x-ray radiography procedures. It provides maximum protection for the areas of the patient's body which are not protected with radiation protection (Lead) apron. The invented device/system is adjustable at different angles and directions to target teeth and comprises of two main segments that provide radiation reduction. The device could be attached to a dental x-ray machine as a mount frame or stand frame or even be hung from the ceiling or wall of the x-ray room. Thicknesses of the radiation protection shield for all parts of device are calculated using radiation physics equations by solving for thickness of radiation shield material(s) with respect to x-ray beam intensity, x-ray beam energy, mass or linear attenuation coefficient and density of radiation protection material(s) to get up to 99.9% radiation reduction.

Priority: CA20052522775 Applic. Date: 2005-10-12

Inventor: MOUSAVI YEGANEH SAEIDEH [CA]

Title: Prevention of dental plaque and dental calculus in animals

Applicant/Assignee:

Application No.: 11/248013   Filing Date: 11/Oct/2005

Abstract:

The present invention provides methods to improve the dental health of an animal, comprising inhibiting dental plaque and calculus on the teeth of a dental plaque- and calculus-forming animal, comprising contacting said teeth with a food product comprising an amount of an antimicrobial agent effective to inhibit dental plaque and inhibit the development of gingivitis in the oral soft tissue of said animal, and with or without an acidulent amount of phosphoric acid, and an amount of a polycarboxylic acid sequestering agent effective to inhibit dental calculus.

Priority:

Inventor: STOOKEY GEORGE K [US]

Title: Composition for the treatment of bad breath

Applicant/Assignee:

Application No.: 10/578621   Filing Date: 29/Sep/2004

Abstract:

A composition suitable for treating bad breath and including a carrier material, at least one enzyme sulphite oxidase, an enzyme for breaking down the starch and/or cellulose present in the oral cavity to give glucose, an enzyme oxidoreductase, a source of halogen or pseudohalogen ions, and an enzyme peroxidase.

Priority: FR20030011384 Applic. Date: 2003-09-29; WO2004IB03637 Applic. Date: 2004-09-29

Inventor: CARDON CHRISTIAAN [BE]

Title: Body care product containing porous silver particles

Applicant/Assignee:

Application No.: 10/570230   Filing Date: 26/Aug/2004

Abstract:

The invention relates to a body care product containing porous particles made of metal containing silver and having an average diameter size of between 1 and 100 mum.

Priority: DE20031040277 Applic. Date: 2003-08-29; WO2004EP09536 Applic. Date: 2004-08-26

Inventor: BECHERT THORSTEN [DE]; WAGENER MICHAEL [DE]; STEINRUCKE PETER [DE]

Title: Active substance combination

Applicant/Assignee: LABORATORIOS DEL DR. ESTEVE S.A

Application No.: 11/543107   Filing Date: 05/Oct/2006

Abstract:

The present invention relates to an active substance combination comprising at least one substituted carbinol compound and at least one opioid, a medicament comprising said active substance combination, a pharmaceutical formulation comprising said active substance combination and the use of said active substance combination for the manufacture of a medicament.

Priority: ES20040000836 Applic. Date: 2004-04-05; ES20040002102 Applic. Date: 2004-08-27; WO2005EP03862 Applic. Date: 2005-04-05

Inventor: BUSCHMANN HELMUT H [ES]; GUTIERREZ SILVA BONIFACIO [ES]; HOLENZ JORG [ES]; FARRE GOMIS ANTONIO [ES]

Title: Method of producing endosseous implants or medical prostheses by means of ion implantation and endosseous implant or medical prosthesis thus obtained

Applicant/Assignee:

Application No.: 10/578849   Filing Date: 13/Nov/2003

Abstract:

The invention relates to a method of producing medical prostheses or implants having a surface microroughness and/or an induced oxide layer, comprising a treatment involving the ionic implantation of controlled amounts of elements such as CO, C, H, N or O in endosseous implants or prostheses produced from metals, metal alloys or biocompatible composite materials. The surface treatment causes changes in the surface characteristics of the endosseous implants or prostheses in terms of nanoroughness, hydrophilic properties and chemical composition, significantly increasing the degree of osseous integration thereof.

Priority: WO2003ES00575 Applic. Date: 2003-11-13

Inventor: ONATE DELA PRESA JOSE I [ES]; ALAVA MARQUINEZ JOSE I [ES]; DE MAEZTU MARTINEZ MIGUEL A [ES]; BRACERAS IZAGUIRRE INIGO [ES]; GARCIA LUIS ALBERTO [ES]

Title: FACE PROTECTOR AND PROTECTIVE SYSTEM

Applicant/Assignee: ALLEN-VANGUARD TECHNOLOGIES, INC

Application No.: 11/425598   Filing Date: 21/Jun/2006

Abstract:

A face protector comprises a protective structure shaped for extending about a person's mandibular region and a mounting for mounting the face protector to a military combat helmet. The protective structure comprises a front portion and opposed left and right side portions extending from the front portion, the front portion having a free upper edge for positioning below eye level and above mouth level when mounted to the helmet, and being sized to extend to below a person's chin. The front portion has inner and outer surfaces, and the mounting is positioned to space the inner surface and the upper edge away from the person's mouth and nose when mounted to the helmet to provide a gap for the passage of ambient air therebetween to permit unobstructed breathing.

The protective structure comprises a ballistic resistant material for providing protection against high velocity fragments from explosive devices.

Priority: US20050692247P Applic. Date: 2005-06-21; US20060774230P Applic. Date: 2006-02-17

Inventor: CROSSMAN DANIEL [CA]; HEDGE CLINT A [CA]; SMITH MARK [CA]; MYLES JUSTIN [CA]

Title: Vial for test strips

Applicant/Assignee: AGAMATRIX, INC

Application No.: 11/252959   Filing Date: 18/Oct/2005

Abstract:

A diagnostic test strip vial has a container, a lid, and a plurality of diagnostic test strips. The container has a generally annular wall terminating at a base and at an open mouth. The lid has a top and a lifting tray connected to the top by a connector that is sufficiently long that the distance between the top and the lifting tray is at least as long as the length of a diagnostic test strip and sufficiently short that the top may engage the open mouth of the container to close the vial when the lifting tray is engaged with the inner side of the annular wall of the container. The test strips are disposed on the lifting tray which is sized to slidably engage the inner side of the annular wall of the container.

Priority:

Inventor: DEMELO ERIK [US]; FLAHERTY JOSEPH [US]; GOLNIK TIMOTHY [US]

Title: Orally-administered live bacterial vaccines for plague

Applicant/Assignee:

Application No.: 10/581466   Filing Date: 09/Dec/2004

Abstract:

The invention provides live, attenuated Salmonella bacterial strains that express one or more plague antigens of Yersinia pestis for use in live vaccine compositions that can be orally administered to an individual to protect against plague.

Priority: US20030528140P Applic. Date: 2003-12-09; US20040559259P Applic. Date: 2004-04-02; US20040573517P Applic. Date: 2004-05-22; US20040610474P Applic. Date: 2004-09-16; WO2004US41282 Applic. Date: 2004-12-09

Inventor: SIZEMORE DONATA [US]; TINGO STEVEN A [US]; KILLEEN KEVIN P [US]

Title: Lozenge for treatment of dry mouth and related conditions

Applicant/Assignee:

Application No.: 11/473046   Filing Date: 23/Jun/2006

Abstract:

A composition and method for the treatment of dry mouth (xerostomia), comprising a sialogogic compound in combination with an effervescent organic acid-based buffering system.

Priority: US20050726191P Applic. Date: 2005-10-14

Inventor: HAYWARD MARSHALL A [US]

Title: Invisible spring aligner

Applicant/Assignee:

Application No.: 11/489115   Filing Date: 19/Jul/2006

Abstract:

An orthodontic appliance for positioning one or more anterior teeth in a jaw of a patient comprising a clear labial component which extends over the labial surfaces of the patient's teeth and which has an anterior portion and a pair of posterior portions on opposite sides of the dental arch. The anterior and posterior portions of the labial component are in direct contact with the exterior surfaces of the teeth so that no other components of the appliance are located between the anterior and posterior portions of the labial component and those exterior surfaces of the teeth. A lingual component is located within the patient's dental arch for supporting the appliance and for applying force to the patient's anterior teeth, the lingual component operating to move the anterior teeth against the anterior portion of the labial component which serves as a reference against which the teeth are positioned.

Priority: US20050700671P Applic. Date: 2005-07-20

Inventor: WILLISON BRIAN D [US]; INMAN DONAL P [US]

Title: Selection of b cells with specificity if interest: method of preparation and use

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 10/556904   Filing Date: 14/May/2004

Abstract:

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides methods using a composition comprising an ordered and repetitive antigen or antigenic determinant array for visualization and selection of B cells specific for the antigen. These B cells are useful for the production of monoclonal antibodies used for therapy, diagnostic or research purposes.

Priority: US20030470443P Applic. Date: 2003-05-15; WO2004EP05208 Applic. Date: 2004-05-14

Inventor: BACHMANN MARTIN F [CH]; GATTO DOMINIQUE [AU]

Title: Angiotensin peptide-carrier conjugates and uses thereof

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 11/540969   Filing Date: 02/Oct/2006

Abstract:

The present invention provides conjugates of peptide derivatives of the mammalian peptide hormones angiotensinogen, angiotensin I and angiotensin II, presented in a repetitive scaffold by coupling the peptide derivatives to a carrier, particularly a virus-like particle (VLP). The invention also provides methods of producing such conjugates, and immunotherapeutic uses of the resulting immunogen conjugates for the therapy and prophylaxis of conditions associated with the renin-activated angiotensin system.

Priority: US2002-264267 Applic. Date: 2002-10-04; US2002-050902 Applic. Date: 2002-01-18; WO2002IB00166 Applic. Date: 2002-01-21; US20010326998P Applic. Date: 2001-10-05; US20010331045P Applic. Date: 2001-11-07; US20020396637P Applic. Date: 2002-07-19

Inventor: BACHMANN MARTIN [CH]

Title: Converting existing prior art fume hoods into high performance low airflow stable vortex fume hoods

Applicant/Assignee: FLOW SAFE INC

Application No.: 11/546964   Filing Date: 12/Oct/2006

Abstract:

The present invention provides a method and conversion kits, that include all necessary components, to convert any style existing prior art fume hood into a stable vortex high performance low airflow fume hood that can accommodate varying size prior art fume hoods without altering the fume hood envelope or customizing the conversion kit. The articulating rear baffle can be lifted out for cleaning debris that collects in baffle conduit. The conversion can be accomplished without drilling mounting holes into an asbestos liner and can be applied on any size or style prior art fume hood. The present invention also provides a new fume hood incorporating the features of the method and kit.

Priority: US20050726561P Applic. Date: 2005-10-14

Inventor: MORRIS ROBERT H [US]; MORRIS STEVEN A [US]

Title: Method of inducing biomineralization method of inducing bone regeneration and methods related thereof

Applicant/Assignee: CARNEGIE MELLON UNIVERSITY

Application No.: 10/568998   Filing Date: 19/Aug/2004

Abstract:

A method of inducing biomineralization in a tissue, which method comprises administering to the tissue a source of Phosphophoryn (PP) in an amount sufficient to induce biomineralization

a method of treating tooth sensitivity or injured pulp tissue

a method of inducing differentiation of a cell into an osteogenic cell or odontogenic cell

a method of inducing bone or dentin regeneration

a method of inducing periodontal regeneration

a method of inducing differentiation of a cell into a cementoblast, osteoblast, or periodontal ligament cell

and a composition comprising a source of PP and a carrier.

Priority: US20030496245P Applic. Date: 2003-08-19; WO2004US27076 Applic. Date: 2004-08-19

Inventor: SFEIR CHARLES [US]; CAMPBELL PHIL [US]; JADLOWIEC JULIE A [US]; KUMTA PRASHANT [US]

Title: Active substance combination comprising a carbinol combined to at least an NSAID

Applicant/Assignee: LABORATORIOS DEL DR. ESTEVE S.A

Application No.: 11/543109   Filing Date: 05/Oct/2006

Abstract:

The present invention relates to an active substance combination comprising at least one substituted carbinol compound and at least one non-steroidal anti-inflammatory drug (NSAID), a medicament comprising said active substance combination, a pharmaceutical formulation comprising said active substance combination for the manufacture of a medicament.

Priority: ES20040000844 Applic. Date: 2004-04-05; WO2005EP03641 Applic. Date: 2005-04-05

Inventor: BUSCHMANN HELMUT H [ES]; GUTIERREZ SILVA BONIFACIO [ES]; HOLENZ JORG [ES]; FARRE GOMIS ANTONIO [ES]

Title: Diaryl Substituted Pyridinones

Applicant/Assignee:

Application No.: 11/531492   Filing Date: 13/Sep/2006

Abstract:

Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.

Priority: US2005-226556 Applic. Date: 2005-09-14; US2003-367987 Applic. Date: 2003-02-14; US20020357029P Applic. Date: 2002-02-14; US20020436915P Applic. Date: 2002-12-30

Inventor: DEVADAS BALEKUDRU [US]; WALKER JOHN [US]; SELNESS SHAUN R [US]; BOEHM TERRI L [US]; DURLEY RICHARD C [US]; DEVRAJ RAJESH [US]; HICKORY BRIAN S [US]; RUCKER PAUL V [US]; JEROME KEVIN D [US]; MADSEN HEATHER M [US]; ALVIRA EDGARDO [US]; PROMO MICHELE A [US]; BLEVIS-BAL RADHIKA M [US]; MARRUTO LAURA D [US]; HITCHCOCK JEFF [US]; OWEN THOMAS [US]; NAING WIN [US]; XING LI [US]; SHIEH HUEY S [US]; SAMBANDAM ARUNA [US]; LIU SHUANG [US]; SCOTT IAN L [US]; MCGEE KEVIN F [US]

Title: COMPOSITION CONTAINING A POLYMERIZABLE REDUCING AGENT, KIT, AND METHOD

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 11/610586   Filing Date: 14/Dec/2006

Abstract:

The present invention provides a hardenable (i.e., curable by polymerization, crosslinking, ionic, or other chemical reaction) composition that includes polymerizable urea or thiourea compounds that function as reductants (i.e., reducing agents) in redox polymerization reactions.

Priority: US2002-121326 Applic. Date: 2002-04-12; US2001-040962 Applic. Date: 2001-12-29

Inventor: MITRA SUMITA B [US]; FALSAFI AFSHIN [US]

Title: TWO-PART SELF-ADHERING DENTAL COMPOSITIONS

Applicant/Assignee: KERR CORPORATION

Application No.: 11/612039   Filing Date: 18/Dec/2006

Abstract:

A method of using a shelf-stable two-part self-adhering dental composition that comprises (a) at least one acidic compound containing at least one acidic moiety selected from the group consisting of where R is an alkyl or aryl group

(b) at least one polymerizable monomer without any acidic group where the polymerizable group is selected from the group consisting of an acrylate, a methacrylate and a vinyl group

(c) a substituted thiourea selected from the group consisting of 1-(2-pyridyl)-2-thiourea and 1-(2-tetrahydrofurfuryl)-2-thiourea

and (d) a hydroperoxide compound with at least one hydroperoxide group attached to a tertiary carbon. The first and second parts are then mixed immediately prior to application, applied to a dental substrate, and hardened. The bond strength of the mixed composition to dentine substrate is at least 3 MPa.

The composition has excellent shelf-life and is self-adhering to various dental substrates such as a tooth, metal alloy and porcelain. It can be used as a filling material, a cement, a liner/base, a pit/fissure sealant, a primer or an adhesive.

Priority: US2003-440804 Applic. Date: 2003-05-19

Inventor: QIAN XUEJUN [US]

Title: Osteoimplants and methods for their manufacture

Applicant/Assignee:

Application No.: 11/489262   Filing Date: 19/Jul/2006

Abstract:

An osteoimplant is made up of a coherent aggregate of elongate bone particles.

Priority: US2005-297735 Applic. Date: 2005-12-08; WO2004US18618 Applic. Date: 2004-06-10; US20030478130P Applic. Date: 2003-06-11

Inventor: BETZ RANDAL R [US]; BODEN SCOTT D [US]; CLARK CHRISTINE [US]; FORSYTH NANETTE [US]; MORRIS JOHN W [US]; TRAIANEDES KATHY [AU]

Title: Packaging device for free-flowing bulk material (filling)

Applicant/Assignee: POLY-CLIP SYSTEM GMBH & CO. KG

Application No.: 11/257492   Filing Date: 24/Oct/2005

Abstract:

The invention pertains to a device for the packaging of free-flowing fill materials in a tube-shaped casing with a feeder tubed to conduct the flow of fill materials. The feeder tube features a hookup, a mouth, a basically straight first segments adjoining the hookup, with a first longitudinal axis, and a second segment that is conjoined with the first segment and proximate to the mouth. The first segment is designed to accept and conduct a casing on its outer surface. The casing infeed consists of a plastic filmstrip, which is formed into a tube around the first feeder tube segment. The second segment is designed to further conduct the plastic filmstrip-derived, newly formed casing. Alternatively, a supply of casing and/or net material may be loaded onto the second segment from its mouth.

Upstream and ahead of the first segment, the feeder tube features a feeder tube swivel bearing ( 140 ) around the first longitudinal axis. There is at least one change of feeder tube direction between the first and second segments.

Priority: DE200510050614 Applic. Date: 2005-10-21

Inventor: TOPFER KLAUS [DE]

Title: Time indicating containers for dental compositions

Applicant/Assignee:

Application No.: 11/258502   Filing Date: 25/Oct/2005

Abstract:

A system for storing a dental composition having a given shelf-life. The storage system includes a container (e.g., a syringe) and activatable time sensitive marking means disposed on or within the container. Upon activation of the time sensitive marking means, the system begins to indicate time lapsed since activation. The time sensitive marking means allows a dental practitioner to determine whether a dental composition within the container has expired, or how much time remains before the composition expires and should either be used up or discarded.

Priority: US2006-537807 Applic. Date: 2006-10-02; US2006-414964 Applic. Date: 2006-05-01

Inventor: LOVERIDGE DAN E [US]; FISCHER DAN E [US]; WAGNER JEFF [US]

Title: Oral composition containing morin

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 11/256784   Filing Date: 24/Oct/2005

Abstract:

The present invention relates to an oral composition useful to reduce inflammatory processes. More specifically, the invention relates to a composition consisting essentially of an anti-oxidative effective amount of morin and a water-humectant phase, and to a composition comprising an anti-oxidative effective amount of morin, one or more anti-bacterial agents and a water-humectant phase. In an embodiment, the composition is used in a method of preventing or treating inflammatory dental diseases such as gingivitis and periodontitis.

Priority:

Inventor: CAMERON RYAN B [US]; SUBRAMANYAM RAVI [US]; TRIVEDI HARSH [US]; WORRELL CORTNEY [US]

Title: Aqueous slurries useful for cleaning teeth and methods related thereto

Applicant/Assignee:

Application No.: 11/490879   Filing Date: 21/Jul/2006

Abstract:

Novel aqueous slurries capable of removing calculus, plaque or stains, adherent to tooth surfaces of a warm-blooded animal, when used in methods that are self-practicable by an individual human or practicable by an individual human on another warm-blooded animal, combine finely-divided charcoal

water

and alcohol, ammonia or hydrogen peroxide to form the slurries. Also disclosed are self-practicable methods that utilize the disclosed aqueous slurries by applying to, and contacting affected tooth surfaces with, the same, then removing the treated calculus, plaque or stains by means of devices and techniques that are safe to use according to the methods. Further, kits are disclosed that comprise the disclosed aqueous slurries, as well as apparatus, devices and tools for effectively using the same for the above purposes.

Priority: US2003-730366 Applic. Date: 2003-12-08; US2002-223060 Applic. Date: 2002-08-15; US2001-773081 Applic. Date: 2001-02-01

Inventor: HARWOOD DOUGLAS B [US]

Title: Compositions and methods of making rapidly dissolving lonically masked formulations

Applicant/Assignee: PFAB LP

Application No.: 11/255555   Filing Date: 21/Oct/2005

Abstract:

The present invention includes compositions and methods for reduce the taste of the drug in the drug resin complex. The composition may include one or more drug-resin complexes and a highly compressible, free-flowing pharmaceutical excipient. The resin is present in an amount effective to reduce the taste of the drug in the drug resin complex relative to an otherwise identical pharmaceutical composition without the resin

and wherein the highly compressible, free-flowing pharmaceutical excipient causes release of the drug-resin complex in the mouth.

Priority:

Inventor: TENGLER MARK [US]; MCMAHEN RUSSELL L [US]

Title: Dental and Endodontic Filling Materials and Methods

Applicant/Assignee: ADA FOUNDATION

Application No.: 11/550543   Filing Date: 18/Oct/2006

Abstract:

Disclosed are endodontic filling materials and methods. A method for filling a dental root canal may include providing a hydrosetting filling material and inserting the hydrosetting filling material into the dental root canal, the material setting in the root canal to form a biocompatible filling. The hydrosetting filling material comprises a hydrogel former and a filler. The hydrogel former is at least one of a reactive organic hydrogel formers, an inorganic hydrogel formers, and a non-reactive organic hydrogel formers, and the filler is at least one of a self-hardening and a non-hardening filler. Plural filling material precursor compositions that collectively contain hydrogel formers and fillers may be provided.

Priority: US20050728838P Applic. Date: 2005-10-21; US20050728888P Applic. Date: 2005-10-21

Inventor: CHOW LAURENCE C [US]; TAKAGI SHOZO [US]

Title: Therapy procedure for drug delivery for trigeminal pain

Applicant/Assignee:

Application No.: 11/511569   Filing Date: 28/Aug/2006

Abstract:

The present invention relates to methods for the treatment or prevention of trigeminal nerve-associated pain, in particular chronic, acute and procedural-related pain. The methods comprise administration of analgesic agents to the trigeminal nerve system which results in analgesia to the facial or head region.

Priority: US20050711950P Applic. Date: 2005-08-26; US20060794004P Applic. Date: 2006-04-21

Inventor: YEOMANS DAVID C [US]; FREY WILLIAM H II [US]; JACOBS DANIEL I [US]

Title: Antigen arrays for treatment of allergic eosinophilic diseases

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 11/499659   Filing Date: 07/Aug/2006

Abstract:

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an array comprising a protein or peptide of IL-5, IL-13 or eotaxin. More specifically, the invention provides a composition comprising a virus-like particle and at least one protein, or peptide of IL-5, IL-13 and/or eotaxin bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of allergic diseases with an eosinophilic component and as a pharmaccine to prevent or cure allergic diseases with an eosinophilic component and to efficiently induce immune responses, in particular antibody responses. Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.

Priority: WO2002IB00166 Applic. Date: 2002-01-21; US2002-289454 Applic. Date: 2002-11-07; US2002-050902 Applic. Date: 2002-01-18; US20010331045P Applic. Date: 2001-11-07; US20020396636P Applic. Date: 2002-07-19; US20010262379P Applic. Date: 2001-01-19; US20010288549P Applic. Date: 2001-05-04; US20010326998P Applic. Date: 2001-10-05

Inventor: BACHMANN MARTIN F [CH]; JENNINGS GARY [CH]; SONDEREGGER IVO [CH]

Title: Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites

Applicant/Assignee:

Application No.: 11/548945   Filing Date: 12/Oct/2006

Abstract:

A composition and method for producing a beneficial effect on a subject's nerve associated with at least one of a cosmetic condition, a dermatological indication and a dental indication and another condition. The composition comprises a hydroxy-oligocarboxylic ester and is formulated for topical administration of the product to a subject to produce the beneficial effect. The method includes topically applying to the subject in a region where the beneficial effect is desired a hydroxy-oligocarboxylic ester in an amount effective to produce the beneficial effect.

Priority: US20060759525P Applic. Date: 2006-01-17; US20050727419P Applic. Date: 2005-10-17

Inventor: YU RUEY J [US]; VAN SCOTT EUGENE J [US]

Title: Methods and systems for treating injured cardiac tissue

Applicant/Assignee: MEDTRONIC VASCULAR, INC

Application No.: 11/643359   Filing Date: 20/Dec/2006

Abstract:

Methods and systems are disclosed for treating injury to cardiac tissue by delivering a composition which provides structural support to the cardiac tissue. The composition helps to prevent chamber remodeling by providing structural reinforcement of the tissue or structural reinforcement of the tissue combined with biological therapy. The structurally reinforcing composition can thicken the wall of a heart, or act to prevent further thinning and thereby provide resistance against further remodeling. A number of compositions are disclosed, including multi-component substances such as autologous platelet gel, and other substances. The compositions disclosed can contain additives to augment/enhance the desired effects of the injection.

Priority: US2006-426211 Applic. Date: 2006-06-23; US20050693749P Applic. Date: 2005-06-23; US20060743686P Applic. Date: 2006-03-23

Inventor: NAYAK ASHA [US]; KEOGH JAMES [US]

Title: Incorporation of antimicrobial combinations onto devices to reduce infection

Applicant/Assignee: GOV. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH AND HUMAN SERVICES

Application No.: 11/586407   Filing Date: 25/Oct/2006

Abstract:

This invention relates to a method for coating a medical device comprising the steps of applying to at least a portion of the surface of the medical device, a bactericidal coating layer, wherein the bactericidal coating layer comprises a bactericidal agent

and applying to at least a portion of the surface of the medical device, a bacteriostatic coating, wherein the bacteriostatic coating layer comprises a bacteriostatic agent wherein the combination of the bactericidal and bacteriostatic agents are in an effective concentration to inhibit growth of microbial organisms relative to an uncoated medical device. The two antimicrobial agents are used to develop a kit comprising these compositions in one container or in separate containers. The kit is used to coat or flush medical devices prior to or after implantation in a mammal.

Priority: US20050729826P Applic. Date: 2005-10-25

Inventor: DAROUICHE RABIH O [US]

Title: Bottle closure with improved thread

Applicant/Assignee: ALCAN PACKAGING CAPSULES

Application No.: 10/561818   Filing Date: 23/Jun/2004

Abstract:

A closure, embodied to cooperate with a neck of a container, the neck, having a wide mouth on the upper part thereof, an external thread and a tapering piece on the lateral wall, for sealing the closure which includes a) an external body having an external head and skirt, b) an insert, enclosed within the body and fixed thereto, including an internal head and skirt, provided with an internal thread, for cooperation with the external thread of the neck and c) a sealing joint, forming an inset piece, fixed to the insert. The joint has a central piece and a border piece. The insert includes a radial compression element, for the sealing joint against the neck, such that when the bottle closure is screwed to the neck, the border is compressed radially between the insert and the neck.

Priority: FR20030007610 Applic. Date: 2003-06-24; WO2004FR01568 Applic. Date: 2004-06-23

Inventor: GRANGER JACQUES [FR]; BOURREAU JEAN-MARIE [FR]

Title: Method and composition for controlling oral pathogens

Applicant/Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

Application No.: 10/551639   Filing Date: 22/Mar/2004

Abstract:

A composition and method of controlling oral and other human pathogens is disclosed. The composition and method utilize an antimicrobial or antibiotic and a berberine as active agents to treat mammals, including humans.

Priority: WO2004US08616 Applic. Date: 2004-03-22

Inventor: WU CHRISTINE D [US]; KIINGHORN A D [US]; ROBERTS SARA K [NZ]

Title: Dental formulation

Applicant/Assignee: DENTAL CREATIONS LLC

Application No.: 11/264429   Filing Date: 31/Oct/2005

Abstract:

An orally absorbable improved dental formulation is provided. The dental formulation, which reduce the occurrence of oral plaque, reduce gingival inflammation and bleeding, and whiten the user's teeth, may be a toothpaste or a rinse which comprises the following active ingredients: carbamide peroxide, papain, xylitol, and coenzyme Q10 (ubiquinone)

Priority:

Inventor: MILLER ROBERT C [US]; KAROLCHYK JOHN S [US]; COVALESKY BERNARD [US]

Title: Antimicrobial decapeptide oral hygiene treatment

Applicant/Assignee:

Application No.: 11/582561   Filing Date: 18/Oct/2006

Abstract:

A method for promoting oral hygiene that treats mature biofilms comprises the step of applying the antimicrobial peptide KSL and a surface active agent to the oral environment of applying KSL after mechanical disruption of the biofilm. An antiplaque chewing gum comprising KSL provides a sustained release oral hygiene treatment.

Priority: US2004-795514 Applic. Date: 2004-03-09; US20030455206P Applic. Date: 2003-03-10; US20050727428P Applic. Date: 2005-10-18; US20050735915P Applic. Date: 2005-11-14

Inventor: LEUNG KAI P [US]

Title: Fluoride-Calcium Compositions, Dental Products, and Methods for Providing Dental Fluoride

Applicant/Assignee: ADA FOUNDATION

Application No.: 11/552414   Filing Date: 24/Oct/2006

Abstract:

Disclosed are dental compositions and methods. In accordance with one embodiment, a dental composition includes calcium, fluorine, which is generally present in the form of fluoride, and phosphate or another stabilizing anion. The composition is stable as against precipitation of calcium fluoride during transport and storage, but is unstable against the precipitation of calcium fluoride in the oral cavity of a human. In many embodiments, the amount of fluoride may be less than the amount of fluoride used in a comparable composition intended for a similar purpose. A dental method comprises applying the composition to the oral cavity of a patient, whereupon calcium fluoride precipitates from the composition.

Priority: US20050730761P Applic. Date: 2005-10-27

Inventor: CHOW LAURENCE C [US]; TAKAGI SHOZO [US]

Title: High strength biological cement composition and using the same

Applicant/Assignee: INNOVATIVE BIOCERAMIX, INC

Application No.: 11/584132   Filing Date: 20/Oct/2006

Abstract:

A hydraulic cement for biomedical applications. The cement sets in-situ, hardening when exposed to water to produce nano-dispersed composite of calcium-silicate-hydrate gel mixed with hydroxyapatite. In comparison with prior cements, the composition provides high biocompatibility, high bioactivity and high biomechanical strength, due to the composite structure of the calcium silicate hydrate reinforced with co-precipitated particles of hydroxyapatite. Biocompatibility is also increased due to an absence of aluminum and magnesium in the composition. The cement is suitable for variety of applications, including dental implants, bone fixation, and bone repair.

Priority: US20050731561P Applic. Date: 2005-10-31

Inventor: LU DONGHUI [CA]; ZHOU SHUXIN [CA]

Title: Implant having integral flexible abutment portion and method for use thereof

Applicant/Assignee:

Application No.: 10/558365   Filing Date: 20/May/2004

Abstract:

The present invention concerns an implant, in particular a dental implant, having a below-shaped adjustable bendable portion and a cavity extending throughout the bendable portion and having an opening. The invention further concerns a method wherein the implant is placed in the bone, the adjustable bending portion is bended to the desired angle and the cavity is filled with a composition that can fix the portion at a desirable angle.

Priority: IL20030156202 Applic. Date: 2003-05-29; WO2004IL00434 Applic. Date: 2004-05-20

Inventor: ILAN DANIEL [IL]; BAR-PELED UD [IL]; MILLER ZVI [IL]; KAPLAN NEHEMIA [IL]

Title: Method of treating dental patients with ultraviolet C range light

Applicant/Assignee:

Application No.: 11/266452   Filing Date: 03/Nov/2005

Abstract:

A method of treating a dental patient includes applying ultraviolet C radiation to the mouth of the patient for a time and at a proximity and intensity sufficient to have a bacteriocidal effect. With this method, the risk of bacterial infection to both the patient and the dentist/oral surgeon can be reduced.

Priority:

Inventor: JOHNSON ROBERT G [US]

Title: Mouthpiece devices and methods to allow UV whitening of teeth

Applicant/Assignee: TWILIGHT TEETH, INC., A CORPORATION TWILIGHT TEETH, INC

Application No.: 11/603301   Filing Date: 21/Nov/2006

Abstract:

A plastic mouthpiece insert for allowing a wearer to whiten their teeth while getting a suntan, and have a generally oblong oval-rectangular opening with a curved rear end that abuts against the root surfaces of the frontal upper and lower teeth of the wearer. A raised front edge can protect the lips and separate in place about the opening to the mouthpiece. Whitening agents can be used to enhance the whitening effect so that ultraviolet light and heat source such as the sun or a sunlamp is all that it is needed. Reflective inner walls in the mouthpiece can magnify light to the teeth. The mouthpiece can include bite tables, and the side walls of the mouthpiece can be inwardly flared and funnel shaped for focusing and magnifying incoming light and heat. The mouthpiece can be colored to protect the inside of the wearer's mouth from receiving any light.

Priority: US2003-668726 Applic. Date: 2003-09-23; US20020413049P Applic. Date: 2002-09-24

Inventor: BAUGHMAN JERALD L [US]

Title: Wearable caddy for a Personal Audio Device having integrated cord storage

Applicant/Assignee:

Application No.: 11/163874   Filing Date: 02/Nov/2005

Abstract:

A wearable caddy for a personal audio device (PAD) adapted to mount at least one PAD and store excess earphone cord. The caddy comprises a front plate and a back plate joined by a plate separating member that creates a space between the plates adapted to store the excess cod by spooling the excess cord around the separating member. The PAD is mounted to the front surface of the front plate using a double-sided adhesive pad. A clear self-adhesive plastic cover is placed over the face of the PAD. More than one pad may be mounted to the same caddy. The caddy clips to the belt of the wearer and can be used to store earphone cord or heavier head-set cord.

Priority:

Inventor: KIELLAND PETER [CA]

Title: Wearable caddy for a personal audio device having integrated cord storage

Applicant/Assignee:

Application No.: 11/307485   Filing Date: 09/Feb/2006

Abstract:

A wearable caddy for a personal audio device (PAD) adapted to mount at least one PAD and store excess earphone cord. The caddy comprises a front plate and a back plate joined by a plate separating member that creates a space between the plates adapted to store the excess cod by spooling the excess cord around the separating member. The PAD is mounted to the front surface of the front plate using a double-sided adhesive pad. A clear self-adhesive plastic cover is placed over the face of the PAD. More than one pad may be mounted to the same caddy. The caddy clips to the belt of the wearer and can be used to store earphone cord or heavier head-set cord.

Priority: US2005-163874 Applic. Date: 2005-11-02

Inventor: KIELLAND PETER [CA]

Title: Regulation of tissue mineralization and phosphate metabolism by asarm peptides

Applicant/Assignee:

Application No.: 10/567938   Filing Date: 20/Sep/2004

Abstract:

Disclosed are methods and compositions for treating diseases and conditions involving abnormal serum phosphorus levels and diseases and conditions involving abnormal mineralization levels of bone, teeth, and soft tissues. Also disclosed are methods and compositions for treating cancer and cancer metastasis.

Priority: US20030504044P Applic. Date: 2003-09-19; WO2004US30530 Applic. Date: 2004-09-20

Inventor: ROWE PETER S [US]

Title: Sialogogue, oral composition and fool product containing the same

Applicant/Assignee:

Application No.: 10/579731   Filing Date: 16/Nov/2004

Abstract:

A sialogogue characterized by comprising polyglutamic acid or its salt. This sialogogue is blended into an oral composition and a food product. This sialogogue is capable of rendering the oral mucosa pleasant even in the case of severe xerostomia.

Priority: JP20030388809 Applic. Date: 2003-11-19; WO2004JP17328 Applic. Date: 2004-11-16

Inventor: UOTANI KAZUMICHI [JP]; KUBOTA HIDETOSHI [JP]; ENDOU HIROYA [JP]; TOKITA FUMIHIKO [JP]

Title: Oxidized lipids and uses thereof in the treatment of inflammatory diseases and disorders

Applicant/Assignee: VASCULAR BIOGENICS LTD

Application No.: 11/528657   Filing Date: 28/Sep/2006

Abstract:

Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.

Priority: US2004-567543 Applic. Date: 2004-05-27; WO2004IL00453 Applic. Date: 2004-05-27; US2003-445347 Applic. Date: 2003-05-27

Inventor: HARATS DROR [IL]; GEORGE JACOB [IL]; HALPERIN GIDEON [IL]; MENDEL ITZHAK [IL]

Title: Thienopyridone derivatives as kinase inhibitors

Applicant/Assignee: CELLTECH R&D LIMITED UCB PHARMA S.A

Application No.: 10/561052   Filing Date: 18/Jun/2004

Abstract:

A series of thieno[2,3-b]pyridin-6(7H)-one derivatives, substituted in the 2-position by a carbonyl- or sulfonyl-linked pyrrolidin-1-yl or related moiety, being inhibitors of p38 MAP kinase, are accordingly of use in medicine, for example in the treatment and/or prevention of immune or inflammatory disorders.

Priority: GB20030014492 Applic. Date: 2003-06-20; GB20030029485 Applic. Date: 2003-12-19; WO2004GB02621 Applic. Date: 2004-06-18

Inventor: LANGHAM BARRY J [GB]

Title: Antimicrobial and anticancer properties of methyl-beta-orcinolcarboxylate from lichen (Everniastrum cirrhatum)

Applicant/Assignee: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH

Application No.: 11/635339   Filing Date: 07/Dec/2006

Abstract:

The present invention relates to the new use of an already known biomolecule methyl-beta-orcinol carboxylate of formula I isolated from a lichen (Everniastrum cirrhatum), for treating pathogenic fungal infections of humans that are resistant to polyene and azole antibiotics such as amphotericin B, nystatin, clotrimazole etc.

Priority: US2003-404012 Applic. Date: 2003-03-31

Inventor: KHANUJA SUMAN P S [IN]; TIRUPPADIRIPULIYUR RANGANATHAN [IN]; GUPTA VIVEK K [IN]; CHAND PREETI [IN]; GARG ANKUR [IN]; SRIVASTAVA SANTOSH K [IN]; VERMA SUBASH C [IN]; SAIKIA DHARMENDRA [IN]; DAROKAR MAHENDRA P [IN]; SHASANY AJIT K [IN]; PAL ANIRBAN [IN]

Title: Catalyst system for dental compositions

Applicant/Assignee:

Application No.: 11/494078   Filing Date: 27/Jul/2006

Abstract:

The present invention relates generally to dental compositions containing polymerizable resins and a catalyst system for accelerating polymerization and hardening of the resins. The composition is prepared from two parts-a base paste containing a polymerizable resin and thiourea compound that acts as a polymerization accelerator and a catalyst paste containing thermally stable hydroperoxide compounds. The dental compositions can be used as crown and bridge materials inlays, onlays, veneers, fillings, sealants, adhesives, cements, and other dental materials.

Priority: US20050704535P Applic. Date: 2005-08-02

Inventor: SUN FUMING [US]

Title: One-pack type adhesive composition for dental use

Applicant/Assignee: KURARAY MEDICAL INC

Application No.: 10/582958   Filing Date: 08/Dec/2004

Abstract:

A hydrophobic acidic group-containing polymeric monomer (a)

a water-soluble polymeric monomer (b)

water (c)

a photopolymerization initiator (d)

an aromatic tertiary amine (e) having an electron-withdrawing group

a cross-linkable polymeric monomer (f)

and a basic compound (g) for producing a water-soluble salt through a reaction with a part of the hydrophobic acidic group-containing polymeric monomer (a) are included as essential compounding ingredients. A one-part dental adhesive composition that exhibits high adhesive strength and high storage stability in adhesion between a teeth, and more particularly enamel or dentine, and a dental repairing material, and more particularly a resin material, is provided.

Since the adhesive composition is one-part type, there is no need to mix in an adhering operation, and in addition, it exhibits high adhesive strength without performing preprocessing (etching processing and priming processing), it is suitably used as a one-step type dental adhesive composition for performing an adhering operation in a teeth repairing treatment in one processing.

Priority: JP20030423790 Applic. Date: 2003-12-19; WO2004JP18272 Applic. Date: 2004-12-08

Inventor: NAKATSUKA KAZUMITSU [JP]; NISHIGAKI NAOKI [JP]

Title: Combined dental floss and tongue scraper

Applicant/Assignee:

Application No.: 11/263940   Filing Date: 02/Nov/2005

Abstract:

A combined dental floss and tongue scraper which comprises: a body portion having an end formed with a notch

a dental floss mounted across said notch

a holding portion being a recess formed on said body portion

and a scraper being a raised edge extending outwardly from another end of said body portion

whereby said dental floss can be used for cleaning spaces between teeth and said scraper for cleaning papillae of a tongue, thereby rendering it easy to carry and keep oral hygiene and cleanliness.

Priority:

Inventor: LEE SUSANNA [TW]

Title: International dining kit

Applicant/Assignee:

Application No.: 11/607322   Filing Date: 01/Dec/2006

Abstract:

The present disclosure teaches an international dining kit comprising a pair of multifunctional chopstick components. The components include a first chopstick component having a fork portion and a first chopstick portion

and a second chopstick component having a spoon portion and a second chopstick portion. The kit can also include additional functionality, such as a knife, a straw, and a dental cleaning component, as well as be disposable and/or biodegradable.

Priority: US2005-200666 Applic. Date: 2005-08-10

Inventor: SHIRAZI KAMRAN [US]

Title: Disinfectant transfer system

Applicant/Assignee: CUSTOM ULTRASONICS, INC

Application No.: 11/267666   Filing Date: 04/Nov/2005

Abstract:

A disinfectant transfer system, which is essentially vapor tight, for transferring toxic and/or noxious fluid from a container to a reservoir without releasing fumes including: a transfer cap for securing onto a mouth of a container containing toxic and/or noxious fluid, the transfer cap having a first opening for letting a gas in through a valve, the transfer cap further having a second opening for allowing toxic and/or noxious fluid to be forced out of the container when the toxic and/or noxious fluid is displaced by the gas entering through the first opening, the gas forces the toxic and/or noxious fluid within the container to enter and flow through a first conduit, which is connected to the bottom of the second opening and leads to the bottom of the container, and to continue to flow through a second conduit which is connected to the top of the second opening and leads to a reservoir into which the toxic and/or noxious fluid can enter.

Priority:

Inventor: PATZEK MICHAEL J IV [US]

Title: Method for the cooling of cleaned items in automatic cleaning and disinfecting machines

Applicant/Assignee: MEIKO MASCHINENBAU GMBH & CO KG

Application No.: 10/576204   Filing Date: 18/Oct/2004

Abstract:

The invention relates to a method and a device for the recooling of cleaned items in automatic cleaning and disinfecting machines for containers containing human excreta. According to the proposed method, the items to be cleaned, which are contained in a chamber ( 1 ), are rinsed off inside said chamber ( 1 ), after which a precleaning rinsing step takes place. The items to be cleaned, which are contained in the chamber ( 1 ), are then subjected to a final cleaning with water that contains a clear rinse additive, before the items to be cleaned are subjected to a disinfection step in the chamber ( 1 ) by introduction of steam into the latter. With the door ( 5 ) closed, air is forcibly introduced into the steam-filled chamber ( 1 ), which leads to steam condensation inside the chamber ( 1 ) and also to cooling and drying of the cleaned items contained in the chamber ( 1 ).

Priority: DE20031048344 Applic. Date: 2003-10-17; WO2004EP11709 Applic. Date: 2004-10-18

Inventor: GAUS BRUNO [DE]; LEHMANN DENIS [DE]; NAGER THOMAS [DE]

Title: Capsule-containing oral composition

Applicant/Assignee: SUNSTAR INC

Application No.: 10/581922   Filing Date: 07/Dec/2004

Abstract:

The present invention provides an oral composition comprising capsule particles that are easily breakable to thereby readily release and distribute the capsule contents when used, while leaving substantially no feeling of capsule component residues or foreign matter in the mouth when rinsing. More specifically, the present invention relates to a capsule-containing oral composition comprising capsules with a capsule breaking point strength of 0.05 N or less when measured using a rheometer.

Priority: WO2004JP18206 Applic. Date: 2004-12-07

Inventor: YASUDA NAOMI [JP]; INOUE ATSUSHI [JP]

Title: TISSUE TARGETED ANTIGENIC ACTIVATION OF THE IMMUNE RESPONSE TO CANCERS

Applicant/Assignee:

Application No.: 11/553972   Filing Date: 27/Oct/2006

Abstract:

The invention provides in part methods of treating cancers of a specific organ or tissue by administering an composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of an immune response to a cancer in a particular tissue or organ. In some embodiments, microbial species of the endogenous flora which are capable of causing infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. The administration of the immunogenic compositions may be repeated relatively frequently over a relatively long period of time, in a dosage that reproduces a consistent visible inflammatory reaction at the successive site or sites of administration, which may for example be by intradermal or subcutaneous injection.

Priority: WO2005CA00812 Applic. Date: 2005-05-30; US20040577206P Applic. Date: 2004-06-07

Inventor: GUNN HAROLD D [CA]

Title: Low radiocarbon nucleotide and amino acid dietary supplements

Applicant/Assignee:

Application No.: 11/344003   Filing Date: 31/Jan/2006

Abstract:

Methods for significantly lowering the carbon-14 content of DNA and histones in vertebrates, especially humans, to about 10% to about 98% below normal background levels and thereby reduce chromosomal damage using dietary supplements based on low radiocarbon nucleotides, amino acids, and other DNA and histone precursors. Administration of the supplements during the earliest and/or most active growth staves of life is particularly beneficial. Components of the low radiocarbon supplements can be produced using the waste carbon dioxide effluent from industrial combustion processes, generally considered a greenhouse gas pollutant. Carbon dating methods can be used to monitor the improvements achieved by the methods and compositions of the invention.

Priority: US2005-267861 Applic. Date: 2005-11-04

Inventor: WILLIAMS CHRISTOPHER P [US]

Title: Elastomeric article with antimicrobial coating

Applicant/Assignee:

Application No.: 11/271666   Filing Date: 10/Nov/2005

Abstract:

A first aspect of the present invention is directed to a surface treatment for elastomeric articles such as medical gloves, comprising a water-based coating formulation and antimicrobial agent(s) embraced therein in an essentially powder-free composition coating. A second aspect of the present invention is directed to a water-based coating formulation for elastomeric articles such as gloves comprising at least one non-volatile water-soluble antimicrobial agent in a controlled-release matrix comprising a blend of a hydrophilic polymer and a hydrophobic component. The controlled-release matrix/blend requirements include: compatibility with the antimicrobial agent, formation of a reservoir of antimicrobial agent, coating film flexibility and lower water-solubility than the antimicrobial agent. A third aspect of the present invention is directed to a method for treating medical gloves comprising dipping, spraying, tumbling or other means for applying to the glove surface a composition to provide medical gloves with sustainable antimicrobial activity.

Priority:

Inventor: WANG SHIPING [US]; BERGER IDA [US]

Title: COMPOSITIONS AND METHODS FOR TREATMENT OF RHINOVIRUS

Applicant/Assignee: THE QUIGLEY CORPORATION

Application No.: 11/553656   Filing Date: 27/Oct/2006

Abstract:

Methods for prophylactic and anti-transmissivity uses of an anti-microbial composition are disclosed. The methods comprise the step of administering to a mammal or a bird, an amount of a composition having a first ingredient obtainable from ginger

a second ingredient obtainable from green tea

an optional third ingredient obtainable from turmeric

and an acceptable carrier. When administered the composition is effective to reduce the incidence of contracting an illness or to prophylactically prevent transmission of an illness. Also disclosed are nasal and throat spray compositions for use in the methods of the invention.

Priority: US2004-012764 Applic. Date: 2004-12-14; US2003-359889 Applic. Date: 2003-02-06; WO2002US24794 Applic. Date: 2002-08-06; US2002-122991 Applic. Date: 2002-04-15; US2001-923090 Applic. Date: 2001-08-06

Inventor: ROSENBLOOM RICHARD A [US]

Title: Substituted bicyclic quinazolin-4-ylamine derivatives

Applicant/Assignee: NEUROGEN CORPORATION

Application No.: 10/571203   Filing Date: 09/Sep/2004

Abstract:

Substituted bicyclic quinazolin-4-ylamine derivatives are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

Priority: US20030501515P Applic. Date: 2003-09-09; US20030515984P Applic. Date: 2003-10-31; WO2004US29583 Applic. Date: 2004-09-09

Inventor: BAKTHAVATCHALAM RAJAGOPAL [US]; BLUM CHARLES A [US]; CHENARD BERTRAND L [US]

Title: Muscarinic acetycholine receptor antagonists

Applicant/Assignee: GLAXO GROUP LIMITED

Application No.: 10/575839   Filing Date: 12/Oct/2004

Abstract:

Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.

Priority: US20030511009P Applic. Date: 2003-10-14; WO2004US33638 Applic. Date: 2004-10-12

Inventor: BUSCH-PETERSEN JAKOB [US]; PALOVICH MICHAEL R [US]; WAN ZEHONG [US]; YAN HONGXING [US]; ZHU CHONGJIE [US]

Title: METHOD FOR INDICATING SHELF-LIFE AFTER MIXING PRE-DOSED, PRE-PACKAGED TWO-PART DENTAL COMPOSITIONS

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/537807   Filing Date: 02/Oct/2006

Abstract:

A pre-dosed, pre-packaged mixing system and associated method for mixing, storing, and dispensing a two-part dental composition that becomes less stable upon mixing. The mixing system includes a pre-dosed, pre-packaged quantity of a first component contained within a first chamber, and a pre-dosed, pre-packaged quantity of a second component contained within a second chamber. The chambers are separated by separation means so as to separate the two-components prior to mixing. Once mixed, the practitioner is able to record a mixing and/or expiration date on at least a portion of the mixing system so as to indicate a shelf-life of the less stable mixed dental composition.

Priority: US2005-258502 Applic. Date: 2005-10-25; US2006-414964 Applic. Date: 2006-05-01

Inventor: FISCHER DAN E [US]

Title: CLEANING PERCEPTION ORAL CARE PRODUCTS

Applicant/Assignee: WHITEHILL ORAL TECHNOLOGIES, INC

Application No.: 11/549668   Filing Date: 16/Oct/2006

Abstract:

Various oral products coated with a saliva soluble coating containing: emulsions, film formers, and/or sialagogue and emulsion mixtures are post-treated with absorbable, stable, volatile flavors released from a reservoir under flavor-sealed conditions, such that, during use, a series of flavor signals are released from said oral products which collectively impart a clean perception.

Priority: US2006-349042 Applic. Date: 2006-02-07; US2006-380331 Applic. Date: 2006-04-26; US2001-005902 Applic. Date: 2001-12-04; US2002-331800 Applic. Date: 2002-12-30; US2005-118911 Applic. Date: 2005-04-29; US2002-334089 Applic. Date: 2002-12-30; US2006-549671 Applic. Date: 2006-10-16; US20060745704P Applic. Date: 2006-04-26

Inventor: HILL IRA D [US]; LEPPLE ROBERT C [US]; BROWN DALE G [US]

Title: Drinking and pouring closure with a piercing cutter device for composite packagings or container and bottle spouts sealed with a film material

Applicant/Assignee:

Application No.: 10/565705   Filing Date: 14/Jul/2004

Abstract:

A drinking and pouring closure includes a spout with a radially downwardly-extending flange for welding into a composite packaging, or a spout with a lower threaded cap molded thereon for screwing onto a bottle thread. A mouth or pouring piece may be plugged onto the spout, which forms a piercing cutter on the inner side of the spout, fitting therein in the form of a nipple. As a result, at least one piercing tip is formed with the lower edge thereof and a cutting edge curving upwardly therefrom at an angle to the nipple rotation axis. The mouth or the pouring sleeve also forms a sleeve on the outer side of the spout, which surrounds the spout. Interlocking guides are molded between the outside of the spout and the inside of the sleeve, which, upon depressing the mouth or pouring piece on the spout, generate a rotation of the mouth or pouring piece on the spout, so that the piercing piece cuts a disc out of the composite or film material and then swings the same downwards.

Priority: CH20030001310 Applic. Date: 2003-07-28; CH20040000650 Applic. Date: 2004-04-14; WO2004CH00448 Applic. Date: 2004-07-14

Inventor: WEIST MARIO [DE]

Title: Centralized product delivery system

Applicant/Assignee:

Application No.: 11/273457   Filing Date: 14/Nov/2005

Abstract:

A centralized product delivery system is provided. A central storage area houses one or more consumer products in one or more product containers with a pipe network from the one or more product containers to a dispensing port in one or more remote locations corresponding to each of the one or more consumer products, and at least one pump moves selected product to the corresponding dispensing port in the one or more remote locations upon demand.

Priority:

Inventor: DOYLE LINDSAY [US]; DOYLE LAURA [US]

Title: Methods and compositions for controlling biofilm development

Applicant/Assignee: UNIVERSITY OF ROCHESTER

Application No.: 11/480286   Filing Date: 30/Jun/2006

Abstract:

A method of cleaning or protecting surfaces by treatment with compositions comprising N-(3-oxododecanoyl)-L-homoserine lactone (OdDHL) blocking compounds and/or N-butyryl-L-homoserine lactone (BHL) analogs, either in combination or separately.

Priority: US2002-188354 Applic. Date: 2002-07-01; US1999-319580 Applic. Date: 1999-06-09; WO1998US12695 Applic. Date: 1998-06-18; US19970050093P Applic. Date: 1997-06-18

Inventor: DAVIES DAVID G [US]; COSTERTON JOHN W [US]; PARSEK MATTHEW R [US]; GREENBERG E P [US]; PEARSON JAMES P [US]; IGLEWSKI BARBARA H [US]

Title: Non-peroxide preparation for whitening natural and manufactured teeth

Applicant/Assignee:

Application No.: 11/281009   Filing Date: 17/Nov/2005

Abstract:

The present invention relates to compositions and methods for the whitening of natural and manufactured teeth without the use of peroxides or abrasives. The active ingredient in the present invention is "actinidin" (crude or purified) and is produced from kiwifruit. The present invention provides for the use of the compositions and methods of the present invention as a tooth whitening agent in a in a strip, tray, floss, dentifrice, rinse, mouthwash or devices like pastilles, chewing gum or lozenges.

Priority:

Inventor: BERGERON CHANTAL [US]

Title: Morinda Citrifolia-Based Oral Care Compositions and Methods

Applicant/Assignee:

Application No.: 11/620878   Filing Date: 08/Jan/2007

Abstract:

Methods and formulations that utilize components of the Indian Mulberry plant, scientifically known as Morinda citrifola L., to treat one or more oral and dental disorders, including periodontal diseases such as gingivitis and periodontitis, tooth decay, halitosis, and other mouth disorders and irritations.

Priority: US2004-948815 Applic. Date: 2004-09-23; US20030506683P Applic. Date: 2003-09-26

Inventor: JENSEN CLAUDE J [US]; PALU AFA K [US]; SU CHEN [US]; ZHOU BING-NAN [US]; ISAMI FUMIYUKI [JP]; OGDEN ROBERT V [US]; STORY STEPHEN P [US]

Title: TREATMENT OF HYPERPHOSPHATEMIA USING CROSSLINKED SMALL MOLECULE AMINE POLYMERS

Applicant/Assignee: ILYPSA, INC

Application No.: 11/465444   Filing Date: 17/Aug/2006

Abstract:

Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.

Priority: US2004-980991 Applic. Date: 2004-11-03; US2004-965044 Applic. Date: 2004-10-13; US2003-701385 Applic. Date: 2003-11-03; US2004-806495 Applic. Date: 2004-03-22

Inventor: CONNOR ERIC [US]; CHARMOT DOMINIQUE [US]; CHANG HAN T [US]; ROGER FLORENCE [US]; KLAEMER GERRIT [US]; HOAI SON [US]

Title: Binding agents

Applicant/Assignee: AMGEN, INC UCB SA AMGEN INC

Application No.: 11/411003   Filing Date: 25/Apr/2006

Abstract:

Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.

Priority: US20060792645P Applic. Date: 2006-04-17; US20060782244P Applic. Date: 2006-03-13; US20060776847P Applic. Date: 2006-02-24; US20050677583P Applic. Date: 2005-05-03

Inventor: PASZTY CHRISTOPHER [US]; ROBINSON MARTYN K [GB]; GRAHAM KEVIN [US]; HENRY ALISTAIR J [GB]; HOFFMANN KELLY S [US]; LATHAM JOHN [US]; LU HSIENG S [US]; LAWSON ALASTAIR [GB]; POPPLEWELL ANDY [GB]; SHEN WENYAN [US]; WINKLER DAVID [US]; WINTERS AARON G [US]

Title: Deposition of discrete nanoparticles on an implant surface

Applicant/Assignee: BIOMET 3L, LLC

Application No.: 11/598610   Filing Date: 13/Nov/2006

Abstract:

A method of forming an implant to be implanted into living bone is disclosed. The method comprises the act of roughening at least a portion of the implant surface to produce a roughened surface. The method further comprises the act of depositing discrete nanoparticles on the roughened surface though a one-step process of exposing the roughened surface to a solution. The nanoparticles comprise a material having a property that promotes osseointegration.

Priority: US20050736269P Applic. Date: 2005-11-14; US20060797810P Applic. Date: 2006-05-04

Inventor: BERCKMANS BRUCE III [US]; TOWSE ROSS W [US]; MAYFIELD ROBERT L [US]

Title: Method for identifying weakly binding molecule fragments having ligand properties, whereby the molecule fragments are applied in the form of microdrops of a corresponding solution to the crystal

Applicant/Assignee: PROTEROS BIOSTRUCTURES GMBH

Application No.: 10/567522   Filing Date: 06/Aug/2004

Abstract:

The present invention relates to a method for treating a crystal with a solution, wherein the solution contains one or more molecule species and wherein the molecules of the molecule species typically have a molecular weight of <500 Da. By means of this method, small molecules or molecule fragments weakly binding on target structures can be identified and their binding position can be determined by means of subsequent X-ray crystallographic examinations.

Priority: DE20031036110 Applic. Date: 2003-08-06; EP20040001722 Applic. Date: 2004-01-27; WO2004EP08813 Applic. Date: 2004-08-06

Inventor: NEUEFEIND TORSTEN [DE]; BRANDSTETTER HANS [DE]; KIEFERSAUER REINER [DE]

Title: Pre-cemented orthodontic appliances

Applicant/Assignee:

Application No.: 11/649666   Filing Date: 04/Jan/2007

Abstract:

An orthodontic appliance and method of pre-applying two dental restoratives thereto of specific viscosities, the appliance including a main body having a bonding tooth-facing surface and retentive elements disposed over a tooth-facing bonding surface. The first dental restorative is applied onto the tooth-facing surface and retentive elements, the first dental restorative having a very low viscosity and being flowable and thus capable of fully penetrating into the retentive elements and being cured therein. The second dental restorative is applied over the cured first dental restorative and left uncured, the second dental restorative having a viscosity substantially higher than that of the first adhesive composition and being highly bondable to the cured first dental restorative and a tooth surface when later cured. The bracket having both the cured and uncured dental restoratives applied thereto is packaged and ready for direct or indirect bonding to teeth.

Priority: US2005-214152 Applic. Date: 2005-08-29; US2005-069303 Applic. Date: 2005-03-01

Inventor: PRIMUS CAROLYN M [US]; ALPERN MICHAEL C [US]

Title: Compressible Content Sac for Dental Prophylaxis Angle with Offset Rotational Axis

Applicant/Assignee:

Application No.: 11/621398   Filing Date: 09/Jan/2007

Abstract:

The present invention discloses a self-contained dental prophylaxis angle with a separate therapeutic content lumen and drive shaft lumen. The phrophylaxis angle also provides an offset rotational axis and methods for its use in cleaning, polishing, bleaching, bonding, etching, abrading, desensitizing, or otherwise treating teeth. An offset drive system is provided to power rotation of the dental tip in a system that can be physically separated from the storage and dispensing system for therapeutic content. A self-contained dental prophylaxis angle with an offset rotational axis according to the present invention may be used with a variety of shaped dental tips of varying degrees of rigidity, according the needs of a given clinical application.

Priority: US2006-421081 Applic. Date: 2006-05-31; US2004-909816 Applic. Date: 2004-08-02

Inventor: STADEKER WILKIE J [US]

Title: Method for the identification of dental plaque, a toothbrush for applying said method and a composition to be used with same

Applicant/Assignee:

Application No.: 11/524217   Filing Date: 20/Sep/2006

Abstract:

This invention refers to a method for the identification of dental plaque, a toothbrush for carrying out said method, and a dental composition, a toothpaste in any of its forms, i.e., liquid, gel, spray, with the addition of fluorescein to be used with same. This composition shall facilitate the visualization, detection, removal, control and certification of DP by the user him/herself, avoiding the development and generation of all DP-related diseases. It is known that the dental plaque is invisible to the human eye, and it is only detectable when it has certain width. This invention proposes the incorporation of fluorescein to a toothpaste, gel, spray or liquid and a visible light for the detection of said plaque. This light shall be incorporated to the toothbrush and/or adjoined to it as an accessory applicable to any type of toothbrush as a kit, with the use of adhesives or with an adhesion, filting or attachment system to the toothbrush's handle.

Priority: AR2005P104732 Applic. Date: 2005-11-11

Inventor: DURSI EDMUNDO M [AR]

Title: Antimicrobial compositions comprising polymeric stabilizers

Applicant/Assignee: BASF AKTIENGESELLSCHAFT

Application No.: 10/581007   Filing Date: 01/Dec/2004

Abstract:

Antimicrobial composition comprising iodide and thiocyanate anions, periodic acid, and nitrogen and/or phosphorous containing polymers.

Priority: GB20030028156 Applic. Date: 2003-12-04; WO2004EP13606 Applic. Date: 2004-12-01

Inventor: ASHWORTH DAIVD W [GB]; HODGKINSON DARREN [GB]; HUFF JURGEN [DE]

Title: P-38 kinase inhibitors

Applicant/Assignee: TRIAD THERAPEUTICS, INC NOVARTIS AG

Application No.: 10/565452   Filing Date: 23/Jul/2004

Abstract:

Compounds and compositions for modulating the activity of p38 kinases are provided, including p38alpha, and p38beta kinase. Methods for treating, preventing or ameliorating one or more symptoms of a p38 kinase mediated disease or disorder are also provided.

Priority: US20030490096P Applic. Date: 2003-07-25; WO2004US23726 Applic. Date: 2004-07-23

Inventor: LANG HENGYUAN [US]; LAN JIONG [US]; FANG YUNFENG [US]

Title: Deposition of discrete nanoparticles on an implant surface

Applicant/Assignee:

Application No.: 11/598614   Filing Date: 13/Nov/2006

Abstract:

A method of forming a nanocrystalline surface on an implant is disclosed. The method comprises the act of roughening at least a portion of the implant surface to form a roughened surface. The method further comprises the act of, without forming an alkoxide on the roughened surface, depositing nanocrystals on the roughened surface. The nanocrystals comprise a material having a property that promotes osseointegration.

Priority: US20050736269P Applic. Date: 2005-11-14; US20060797810P Applic. Date: 2006-05-04

Inventor: BERCKMANS BRUCE III [US]; TOWSE ROSS W [US]; MAYFIELD ROBERT L [US]

Title: DENTAL PROSTHESIS METHOD AND ALLOYS

Applicant/Assignee:

Application No.: 11/627079   Filing Date: 25/Jan/2007

Abstract:

Dental prostheses are fabricated as a metallic alloy body by a technique that produces scrap alloy. Suitable gold base alloys have only base metal alloying additions which are more readily oxidized than gold and when combined with the gold can be age hardened. Exemplary metals include titanium, zirconium, yttrium and chromium. Scrap from fabricating a dental prosthesis is melted in air so that the base metals are all oxidized and substantially pure gold is reclaimed for reuse in new alloys.

Priority: US2004-846314 Applic. Date: 2004-05-14

Inventor: CASCONE PAUL J [US]

Title: Shaping paste, their use as well as procedure for the production of a ceramic body

Applicant/Assignee: HERAEUS KULZER GMBH

Application No.: 11/451136   Filing Date: 12/Jun/2006

Abstract:

A molding paste for use in ceramic molding containing at least one release agent, at least one ion-donating agent, and/or an amphoteric substance has in particular an electrostatically destabilizing effect on ceramic slips.

Priority: DE200510028721 Applic. Date: 2005-06-20

Inventor: KOOPS ULRICH [DE]; HUHN ROBIN [DE]; WEISS OZLEM [DE]

Title: High stability package for dental treatment devices

Applicant/Assignee: ULTRADENT PRODUCTS, INC

Application No.: 11/284472   Filing Date: 22/Nov/2005

Abstract:

A pre-packaged dental treatment system including a dental treatment device having a barrier layer configured for placement over at least a portion of a person's teeth, a dental treatment composition (e.g., a bleaching composition) disposed adjacent to the barrier layer, and a sealed packaging container within which the dental treatment device is disposed. At least a portion of the packaging container includes a laminated polymer material that is substantially impervious to water molecules, which prevents the dental treatment composition from drying out. The laminated polymer material is optionally also a barrier to oxygen molecules.

Priority:

Inventor: MOORE SCOTT E [US]

Title: Sports water bottle

Applicant/Assignee:

Application No.: 11/284063   Filing Date: 21/Nov/2005

Abstract:

A sports water bottle includes a container, a lid, a resilient member and a spout. The lid is mounted onto the container detachably and has a tube and an upper rim. The tube has an outer surface. The upper rim is formed around the outer surface, has an inner surface and defines a recess. The resilient member has a stationary end and a slidable end. The stationary end is mounted on the inner surface of the upper rim. The slidable end is mounted in the recess. The spout is mounted onto the lid slidably and inserted into the tube. The slidable end of the resilient member can be pushed to bend up the resilient member to push up the spout to drink water from the container. Pushing the stationary end of the resilient member is a more sanitary way to push up the spout.

Priority:

Inventor: LEE YU-YUAN [TW]

Title: Ergonomically-designed multi-chamber and multi-nozzle squeeze bottle

Applicant/Assignee:

Application No.: 11/285941   Filing Date: 23/Nov/2005

Abstract:

An ergonomically-designed multi-chamber and multi-nozzle squeeze bottle comprising a plurality of separable and cooperatively-engageable chambers, wherein each chamber comprises a main reservoir portion in fluid communication with a tapered and elongated spout portion or feed neck that extends angularly and downwardly therefrom. The terminal end of each feed neck comprises a dedicated nozzle or lid associated therewith, whereupon cooperative-engagement of each chamber portion provides the multi-chamber and multi-nozzle squeeze bottle of the present invention. The present bottle is structurally configured to displace the weight of the sauce/condiment-filled bottle over the user's hand so as to alleviate hand strain and fatigue during use, and to enable equal distribution of hand and finger pressure over the bottle, such that all separate chambers thereof equally receive the requisite compressive force for delivery of smooth, even and controlled lines of dispensed sauces, condiments, liquids, and/or the like.

Priority:

Inventor: DODRILL JOHN [US]

Title: Low radiocarbon nucleotide and amino acid dietary supplements

Applicant/Assignee:

Application No.: 11/267861   Filing Date: 04/Nov/2005

Abstract:

Methods for significantly lowering the carbon-14 content of DNA and histones in vertebrates, especially humans, to about 10% to about 98% below normal background levels and thereby reduce chromosomal damage using dietary supplements based on low radiocarbon nucleotides, amino acids, and other DNA and histone precursors. Administration of the supplements during the earliest and/or most active growth stages of life is particularly beneficial. Components of the low radiocarbon supplements can be produced using the waste carbon dioxide effluent from industrial combustion processes, generally considered a greenhouse gas pollutant. Carbon dating methods can be used to monitor the improvements achieved by the methods and compositions of the invention.

Priority:

Inventor: WILLIAMS CHRISTOPHER P [US]

Title: STORAGE AND SUPPLY SYSTEM FOR CLINICAL SOLUTIONS USED IN AN AUTOMATIC ANALYZER

Applicant/Assignee: DADE BEHRING INC

Application No.: 11/560220   Filing Date: 15/Nov/2006

Abstract:

A fluid handling system adapted to provide storage and supply of a number of liquid solutions to an automatic clinical analyzer having three different bottle-like containers, a collapsible plastic-metal-plastic pouch having a mouth-like opening, a fitment to be sealed within mouth-like opening a septum within the fitment, and open meal band or cap to seal the septum into the fitment.

Priority: US20050739899P Applic. Date: 2005-11-23

Inventor: WALTERS JAY M [US]; CARRIO JEANNINE M [US]; THOMPSON DAVID R [US]; LLOYD MARK R [US]; PARMER JEFFREY K [US]; WARWICK RICHARD G [US]; SHIELDS THOMAS P [US]; HUPPMAN LAWRENCE D [US]

Title: Red herbal dentifrice

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 11/330786   Filing Date: 12/Jan/2006

Abstract:

A dentifrice composition of the invention can be applied to teeth and/or gums by any conventional A dentifrice composition comprises (a) calcium carbonate having properties of particle size and angularity effective to provide mild abrasivity to dental enamel

(b) red iron oxide of low abrasivity in an effective amount on which to impart red color to the composition

and (c) a herbal component comprising at least one botanical or extract thereof, in a total herbal component amount effective to promote oral health.

Priority: IN2005DE03081 Applic. Date: 2005-11-18

Inventor: KAMATH SHRIDHARA [IN]; NAIR RAMESH [IN]

Title: Novel methods and medicament for treating infectious diseases involving microbial biofilms

Applicant/Assignee:

Application No.: 11/480676   Filing Date: 03/Jul/2006

Abstract:

The present invention provides a method for prophylaxis and therapy of infectious diseases caused by microorganisms present in biofilms adherent to cell surfaces comprising the step of administering to an individual in need thereof a composition comprising a combination of at least one compound chosen from the group of peroxidase, lactoferrin, lactoferrin peptides, lysozyme and immunoglobulins and at least one growth factor.

Priority: EP19990870145 Applic. Date: 1999-07-07; US2002-048708 Applic. Date: 2002-04-05; WO2000EP06312 Applic. Date: 2000-07-05

Inventor: PERRAUDIN JEAN-PAUL [BE]

Title: Apparatus and method for preventing adhesions between an implant and surrounding tissues

Applicant/Assignee: MACROPORE BIOSURGERY, INC MAST BIOSURGERY AG

Application No.: 11/653064   Filing Date: 12/Jan/2007

Abstract:

An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, such as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.

Priority: US2003-632014 Applic. Date: 2003-07-31; US20020409137P Applic. Date: 2002-09-09; US20020399813P Applic. Date: 2002-07-31

Inventor: CALHOUN CHRISTOPHER J [US]; HOLMES RALPH E [US]; CORNWALL G B [US]

Title: Dental Composition with High-Potency Sweetener

Applicant/Assignee: THE COCA-COLA COMPANY

Application No.: 11/556052   Filing Date: 02/Nov/2006

Abstract:

The present invention relates generally to dental compositions comprising non-caloric or low-caloric high-potency sweeteners and methods for making and using them. In particular, the present invention relates to different dental compositions comprising at least one non-caloric or low-caloric natural and/or synthetic high-potency sweetener, at least one sweet taste improving composition, and an active dental substance. The present invention also relates to dental compositions and methods that can improve the tastes of non-caloric or low-caloric natural and/or synthetic, high-potency sweeteners by imparting a more sugar-like taste or characteristic. In particular, the dental compositions and methods provide a more sugar-like temporal profile, including sweetness onset and sweetness linger, and/or a more sugar-like flavor profile.

Priority: US20050739302P Applic. Date: 2005-11-23; US20050739124P Applic. Date: 2005-11-23; US20060805216P Applic. Date: 2006-06-19; US20060805209P Applic. Date: 2006-06-19

Inventor: PRAKASH INDRA [US]; DUBOIS GRANT E [US]

Title: Antigen arrays for treatment of bone disease

Applicant/Assignee: CYTOS BIOTECHNOLOGY AG

Application No.: 11/589321   Filing Date: 30/Oct/2006

Abstract:

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular a RANKL protein, RANKL fragment or RANKL peptide-VLP-array. More specifically, the invention provides a composition comprising a virus-like particle and at least one RANKL protein, RANKL fragment or RANKL peptide bound thereto. The invention also provides a process for producing the conjugates and the ordered and repetitive arrays, respectively. The compositions of the invention are useful in the production of vaccines for the treatment of bone diseases and as a pharmaccine to prevent or cure bone diseases and to efficiently induce immune responses, in particular antibody responses.

Furthermore, the compositions of the invention are particularly useful to efficiently induce self-specific immune responses within the indicated context.

Priority: US2002-289456 Applic. Date: 2002-11-07; US2002-050902 Applic. Date: 2002-01-18; WO2002IB00166 Applic. Date: 2002-01-21; US20010331045P Applic. Date: 2001-11-07; US20020396635P Applic. Date: 2002-07-19; US20010262379P Applic. Date: 2001-01-19; US20010288549P Applic. Date: 2001-05-04; US20010326998P Applic. Date: 2001-10-05

Inventor: BACHMANN MARTIN [CH]; MAURER PATRIK [CH]; SPOHN GUNTHER [CH]

Title: Clamp

Applicant/Assignee:

Application No.: 11/560992   Filing Date: 17/Nov/2006

Abstract:

A clamp for securing a circuit board 10 beneath a stencil whilst solder is printed onto pads 11 on the circuit board 10, comprises a mount 12 and an elongate clamping member 17, in the form of a metal strip, mounted in a mouth 18 of the of the mount 12. A longitudinal side edge of the clamping member 17 extends outwardly from the side surface of the mount 12, the upper surface of the clamping member 17 lying in substantially the same plane as the upper surface of the mount 12. The projecting longitudinal side edge of the clamping member 17 comprises a plurality of frangible regions, which can be broken off so that the clamping member 17 only engages points on the side edge of the circuit board 10 which are free of pads 11.

Priority: GB20050023503 Applic. Date: 2005-11-18; GB20060021116 Applic. Date: 2006-10-24

Inventor: HANSFORD KEITH M [GB]

Title: Defensin-inducing agents and related methods

Applicant/Assignee: CASE WESTERN RESERVE UNIVERSITY

Application No.: 10/538811   Filing Date: 09/Mar/2006

Abstract:

This application provides, in part, novel polypeptides and nucleic acids that affect induction of defensins, and methods of making and using same.

Priority: US20020433100P Applic. Date: 2002-12-13; WO2003US40221 Applic. Date: 2003-12-15

Inventor: WEINBERG AARON [US]

Title: Method for preparing drug eluting medical devices and devices obtained therefrom

Applicant/Assignee:

Application No.: 10/577932   Filing Date: 07/Nov/2003

Abstract:

The present invention relates to a method for preparing a drug eluting medical device comprising the application to a stent of a polymer having functional groups capable of chemically binding biological molecules, characterised in that said application is carried out in a single step by means of cold plasma methods. Moreover, the invention also relates to a medical device obtained therefrom.

Priority: WO2003IB05003 Applic. Date: 2003-11-07

Inventor: GAZZA GIANLUCA [MC]

Title: Fuel Vapor Recovery Canister

Applicant/Assignee: STANT MANUFACTURING INC

Application No.: 11/624063   Filing Date: 17/Jan/2007

Abstract:

A vehicle fuel system includes a fuel vapor recovery canister containing a carbon bed configured to capture hydrocarbon material associated with fuel vapor discharged from the fuel tank into the canister. A purge vacuum is applied to the canister to draw fuel vapor carrying reclaimed hydrocarbon material from the canister into an intake manifold coupled to an engine so that the reclaimed hydrocarbon material can be burned in the engine.

Priority: US2005-202966 Applic. Date: 2005-08-12

Inventor: KING TIMOTHY J [US]

Title: Dental floss having a fractionated bee propolis coating

Applicant/Assignee: CC POLLEN CO., ARIZONA, USA

Application No.: 11/287468   Filing Date: 28/Nov/2005

Abstract:

Dental floss coated with a composition containing fractioned propolis wax isolated without the use of solvents. The dental floss coating composition contains about 24-50 mg/g of total polyphenols, about 11-18% resins, about 77-87% wax, about 2.4-5.0% polyphenols and about 0-5% other materials.

Priority:

Inventor: HUDNALL MICHAEL [US]; ARTISS FRANK [JP]

Title: WINE GLASS

Applicant/Assignee:

Application No.: 11/668046   Filing Date: 29/Jan/2007

Abstract:

A wine glass constructed from molded plastic includes an upper body defining an upwardly narrowed flume for concentrating the wine bouquet, in combination with a contoured lower base defining an annular moat surrounding a central punt for enhanced visual inspection of the wine. In addition, the upper body further includes a notched indent at an outboard side thereof forming a shelf for facilitated fingertip grasping and manipulation of the assembled glass. In one form, the upper body and lower base of the wine glass are provided as separate modules adapted for assembly to form the wine glass, and disassembly for respective compact stacking. In another form, the wine glass has a one-piece construction adapted for compact stacking by nested reception of the upwardly narrowed flume partially into the underside of the lower base of an overlying glass in the stack.

Priority: US2006-309159 Applic. Date: 2006-07-03; US2004-979847 Applic. Date: 2004-11-01

Inventor: WILLAT BOYD I [US]; PERRULLI JOSEPH T [US]; VELICK PAUL H [US]

Title: Pumping and floating pistons coated with a barrier layer

Applicant/Assignee:

Application No.: 10/570974   Filing Date: 09/Sep/2004

Abstract:

Pumping and floating pistons ( 70 ) suitable for a hand pump ( 10 ) for a viscous fluid material such as a toothpaste, made of a plastics material coated with a barrier layer ( 75 ). A preferred barrier layer is a thermoplastic elastomer. The barrier layer of the pumping piston may be integrally formed into a one way outlet valve. The barrier layer reduces leakage of components of the fluid material out through the piston, or ingress of environmental components through the piston.

Priority: GB20030021332 Applic. Date: 2003-09-11; WO2004EP10171 Applic. Date: 2004-09-09

Inventor: KRAEMER HANS [DE]

Title: Drug condensation aerosols and kits

Applicant/Assignee:

Application No.: 11/504419   Filing Date: 15/Aug/2006

Abstract:

The present invention provides novel condensation aerosols for the treatment of disease and/or intermittent or acute conditions. These condensation aerosols have little or no pyrolysis degradation products and are characterized by having an MMAD of between 1-3 microns. These aerosols are made by rapidly heating a substrate coated with a thin film of drug having a thickness of between 0.05 and 20 mum, while passing a gas over the film, to form particles of a desirable particle size for inhalation. Kits comprising a drug and a device for producing a condensation aerosol are also provided The device contained in the kit typically, has an element for heating the drug which is coated as a film on the substrate and contains a therapeutically effective dose of a drug when the drug is administered in aerosol form, and an element allowing the vapor to cool to form an aerosol. Also disclosed, are methods for using these aerosols and kits.

Priority: US2002-302010 Applic. Date: 2002-11-21; US2002-302614 Applic. Date: 2002-11-21; US2002-322227 Applic. Date: 2002-12-17; US2003-633877 Applic. Date: 2003-08-04; US2003-633876 Applic. Date: 2003-08-04; US2003-718982 Applic. Date: 2003-11-20; US2001-057197 Applic. Date: 2001-10-26; US2001-057198 Applic. Date: 2001-10-26; US2002-146080 Applic. Date: 2002-05-13; US2002-146086 Applic. Date: 2002-05-13; US2002-146088 Applic. Date: 2002-05-13; US2002-146515 Applic. Date: 2002-05-13; US20010296225P Applic. Date: 2001-06-05; US20010294203P Applic. Date: 2001-05-24; US20010317479P Applic. Date: 2001-09-05; US20010345882P Applic. Date: 2001-11-09; US20010345145P Applic. Date: 2001-11-09; US20010345876P Applic. Date: 2001-11-09; US20010332280P Applic. Date: 2001-11-21; US20010336218P Applic. Date: 2001-10-30; US20010335049P Applic. Date: 2001-10-30; US20020371457P Applic. Date: 2002-04-09; US20010332279P Applic. Date: 2001-11-21; US2002-146516 Applic. Date: 2002-05-13; US2002-150056 Applic. Date: 2002-05-15; US20010332165P Applic. Date: 2001-11-21; US20010342066P Applic. Date: 2001-12-18; US20020412068P Applic. Date: 2002-09-18; US2002-150267 Applic. Date: 2002-05-15; US2002-150268 Applic. Date: 2002-05-15; US2002-150591 Applic. Date: 2002-05-17; US2002-150857 Applic. Date: 2002-05-17; US2002-151596 Applic. Date: 2002-05-16; US2002-151626 Applic. Date: 2002-05-16; US2002-152639 Applic. Date: 2002-05-20; US2002-152640 Applic. Date: 2002-05-20; US2002-152652 Applic. Date: 2002-05-20; US2002-153139 Applic. Date: 2002-05-20; US2002-153311 Applic. Date: 2002-05-21; US2002-153313 Applic. Date: 2002-05-21; US2002-153831 Applic. Date: 2002-05-21; US2002-153839 Applic. Date: 2002-05-21; US2002-154594 Applic. Date: 2002-05-23; US2002-154765 Applic. Date: 2002-05-23; US2002-155097 Applic. Date: 2002-05-23; US2002-155373 Applic. Date: 2002-05-22; US2002-155621 Applic. Date: 2002-05-22; US2002-155703 Applic. Date: 2002-05-22; US2002-155705 Applic. Date: 2002-05-22; US2002-280315 Applic. Date: 2002-10-25

Inventor: HALE RON L [US]; HODGES CRAIG C [US]; LLOYD PETER M [US]; LU AMY T [US]; MYERS DANIEL J [US]; RABINOWITZ JOSHUA D [US]; WENSLEY MARTIN J [US]; MCKINNEY JEFFREY A [US]; ZAFFARONI ALEJANDRO C [US]

Title: GLASS COMPOSITIONS AS AN ANTIMICROBIAL ADDITIVE FOR DENTAL MATERIALS

Applicant/Assignee: SCHOTT AG

Application No.: 10/599807   Filing Date: 25/May/2005

Abstract:

The invention relates to a use of glass compositions having an antimicrobial and/or disinfectant effect in materials used for restoring teeth, excluding implants.

Priority: DE200410026432 Applic. Date: 2004-05-29; WO2005EP05632 Applic. Date: 2005-05-25

Inventor: KESSLER SUSANNE [DE]; FECHNER JORG H [DE]; SENSCHAL KARINE [DE]; ZIMMER JOSE [DE]

Title: Dentifrice composition

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY

Application No.: 11/545266   Filing Date: 10/Oct/2006

Abstract:

Dentifrice compositions which provide chemical cleaning of the oral surfaces with a combination of surfactant, chelant, and pH

further this dentifrice composition can minimize the use of abrasives to provide a gentle cleaning of the oral surfaces.

Priority: US20050740538P Applic. Date: 2005-11-29

Inventor: GLANDORF WILLIAM M [US]

Title: Nonaqueous gel composition for tooth whitening and tooth whitening set

Applicant/Assignee: LION CORPORATION

Application No.: 10/584192   Filing Date: 24/Dec/2004

Abstract:

A nonaqueous gel composition for tooth whitening, comprising: (A) tooth whitening ingredient having a relative permittivity of 17.0 to 43.0 (at 25 DEG C.) and a vapor pressure of 0 to 7000 kPa (at 25 DEG C.), (B) substance that is soluble in the tooth whitening ingredient and is precipitated by an aqueous solution of calcium chloride, and (C) gelling agent, which nonaqueous gel composition contains substantially none of water and peroxide. This tooth whitening component can penetrate into the enamel surface layer of teeth to thereby alter the optical properties, such as refractive index and reflectance, of the enamel so that the enamel is apparently whitened. The whitened teeth can be restored to the original tooth color in a reversible manner in the presence of water. Further the persistence of reversible whitening effect can be strikingly enhanced by the nonaqueous gel composition.

Priority: JP20030432095 Applic. Date: 2003-12-26; WO2004JP19344 Applic. Date: 2004-12-24

Inventor: ONIKI TAKAYUKI [JP]; UCHIYAMA AKIRA [JP]; FUKUDA YASUSHI [JP]; INOUE SHIMAKO [JP]

Title: Tooth colorant and whitener, method of manufacture, and method of use thereof

Applicant/Assignee:

Application No.: 11/289764   Filing Date: 29/Nov/2005

Abstract:

A polymerizable tooth colorant composition, comprising: a polymerizable resin composition

an additive composition comprising a colorant, a whitener, or both

and a curing system. The composition allows easy coloring and/or whitening of teeth.

Priority:

Inventor: JIA WEITAO [US]

Title: HYDROGEL SHEETS AND SHAPES FOR ORAL CARE

Applicant/Assignee:

Application No.: 11/563634   Filing Date: 27/Nov/2006

Abstract:

A hydrogel for use in oral care. The hydrogel is ion beam cross-linked, the hydrogel is adapted to be disposed in the oral cavity and may be adapted to provide a denture fixative or may be loaded with a whitening agent for use in whitening one or more teeth and disposed on or adjacent one or more teeth and the whitening agent is slow-released to whiten the one or more teeth. Other loading materials may include materials for treatment of alveolitis or malodor, inter alia. The present invention is a new hydrophilic oral and dental cohesive hydrogel sheet designed to securely grip and cushion prosthetic devices in the human mouth with the further ability to slow release antimicrobial or other orally desirable agents. Additionally, the invention also provides a method of making an orally cohesive device that: 1) is easily adapted and applied to a removable dental prosthesis

2) bonds well to alveolar ridge/palatal mucosa and denture acrylic materials

and 3) releases cleanly, with no tacky or thixotropic residue when the prosthesis is removed. The cohesive hydrogel gel device is a hydrogel-forming polymer mixed with water, optionally surrounding an internal scrim, and uses an electron-beam energy source to cause cross-linking. The method does not need any chemical additive to affect the cross-linking. Furthermore the beam energy can be adjusted to optimize the cohesive properties of either side of the device, as well as to compensate for addition of orally active agents, if any are chosen. The hydrogel sheets are pre-cut to fit most sizes of maxillary and mandibular full denture prostheses, but can be easily trimmed with a scissors by the end user for the ideal custom fit of any full or partial denture, in either arch.

Priority: US20050739633P Applic. Date: 2005-11-26

Inventor: GINIGER MARTIN S [US]; SPAID MATTHEW S [US]

Title: CORPOREAL DELIVERY OF CAROTENOIDS

Applicant/Assignee:

Application No.: 11/563617   Filing Date: 27/Nov/2006

Abstract:

A method for delivery of a phytochemical supplement to a corporeal body. The method of delivery comprises providing a phytochemical supplement in an orally acceptable composition and applying the orally acceptable composition including the phytochemical supplement in contact with a feature of the oral cavity of a corporeal body. An oral care composition comprising a phytochemical supplement for one or more of ingestion or trans-mucosal absorption and a method for making the same are also disclosed.

Priority: US20050739635P Applic. Date: 2005-11-26

Inventor: GINIGER MARTIN S [US]; SPAID MATTHEW S [US]; OLSON BRIAN [US]

Title: Process for recombinant expression and purification of antimicrobial peptides using periplasmic targeting signals as precipitable hydrophobic tags

Applicant/Assignee: E. I. DU PONT DE NEMOURS AND COMPANY

Application No.: 11/287809   Filing Date: 28/Nov/2005

Abstract:

A process was developed for expressing antimicrobial peptides in a recombinant host cell that eliminates host cell toxicity and antimicrobial peptide degradation, as well as providing a process for rapid purification. Fusion proteins comprising a periplasmic targeting signal, cleavage site, and antimicrobial peptides provide the basis for this process which produces antimicrobial peptides that may be used in antimicrobial compositions and articles.

Priority:

Inventor: KEELER SHARON J [US]; WOLSTENHOLME SHERYL M [US]; DUKE JODIE L [US]; HNATOW LINDA L [US]

Title: Taste masking composition

Applicant/Assignee:

Application No.: 11/657429   Filing Date: 24/Jan/2007

Abstract:

A composition for delivery of a medicament that has a bitter taste and/or causes throat catch is provided. The composition contains Carbomer 934, Carbomer 971, Carbomer 974, PEG-5M or a mixture thereof in an amount sufficient to mask the bitter taste of the medicament and/or throat catch.

Priority: US2002-210484 Applic. Date: 2002-08-01; US20010309285P Applic. Date: 2001-08-01

Inventor: CORBO MICHAEL [US]; MIGTON JOHN [US]; PATELL MAHESH [US]

Title: N- or C- terminally modified small peptides

Applicant/Assignee: ZEALAND PHARMA A/S WYETH

Application No.: 11/482365   Filing Date: 07/Jul/2006

Abstract:

N- or C-terminally modified small peptides having antiarrhythmic properties are disclosed, and in particular small peptides that possess improved pharmacokinetic properties such as having a reduced tendency to inhibit the activity of isozyme 3A4 of cytochrome P450 oxidase. The invention further relates to uses of said compounds in the preparation of a medicament, and to pharmaceutical compositions comprising said compounds.

Priority: GB20050014071 Applic. Date: 2005-07-07; US20050697138P Applic. Date: 2005-07-07

Inventor: LARSEN BJARNE D [DK]; KERNS EDWARD H [US]

Title: Benzopyranone compounds, compositions thereof, and methods for treating or preventing cancer

Applicant/Assignee:

Application No.: 11/473564   Filing Date: 23/Jun/2006

Abstract:

This invention relates to Benzopyranone Compounds, compositions comprising a Benzopyranone Compound and methods for treating or preventing cancer or inhibiting the growth of a cancer cell or neoplastic cell comprising administering an effective amount of a Benzopyranone Compound to a patient in need thereof. The Benzopyranone Compounds have the formula: including pharmaceutically acceptable salts thereof, wherein R1 and n are as defined herein.

Priority: US20050693867P Applic. Date: 2005-06-24

Inventor: SAKATA STEVEN T [US]; NARLA RAMA K [US]; STEIN BERND [US]; MISSBACH MARTIN [CH]; RENAUD JOHANNE [CH]

Title: Non-nucleotide compositions and method for treating pain

Applicant/Assignee: INSPIRE PHARMACEUTICALS, INC

Application No.: 10/576859   Filing Date: 21/Oct/2004

Abstract:

The present invention is directed to a method of treating pain. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a P2X receptor antagonist. The methods of the present invention are useful in reducing pain, such as traumatic pain, neuropathic pain, organ pain and/or pain associated with diseases. The P2X receptor antagonists useful for this invention are non-nucleotide compounds of general Formula I. Compounds of Formula I can be used alone to treat pain. Compounds of Formula I can also be used in conjunction with other therapeutic agents or adjunctive therapies commonly used to treat pain, thus enhancing the therapeutic effect of pain reduction.

Priority: US20030513844P Applic. Date: 2003-10-21; WO2004US35396 Applic. Date: 2004-10-21

Inventor: PLOURDE ROBERT JR [US]; SHAVER SAMMY R [US]; ABREO MELWYN A [US]; ALFARO-LOPEZ LORENZO J [US]; FENG YANGHO [US]; KHASANOVA TATYANA V [US]; HOLLADAY MARK W [US]; CREAN CHRISTOPHER S [US]

Title: Compositions and methods for treating middle-of-the-night insomnia

Applicant/Assignee: TRANSORAL PHARMACEUTICALS, INC

Application No.: 11/439884   Filing Date: 23/May/2006

Abstract:

The present invention provides compositions and methods for treating middle-of-the-night insomnia without residual sedative effects upon awakening by administering low doses (about 5 mg or less) of zolpidem or a salt thereof.

Priority: US20050684842P Applic. Date: 2005-05-25; US20050741673P Applic. Date: 2005-12-01; US20060788340P Applic. Date: 2006-03-31; US20060788249P Applic. Date: 2006-03-31

Inventor: SINGH NIKHILESH [US]; PATHER SATHASIVAN I [US]

Title: Use of thermal reversible associations for enhanced polymer interactions

Applicant/Assignee: BAUSCH & LOMB INCORPORATED

Application No.: 11/595385   Filing Date: 09/Nov/2006

Abstract:

The present invention relates generally to the development of medical devices which show thermal reversible associations with similar polymer molecules contained in the majority of device care solutions. The thermal reversible association provides an enhanced interaction which leads to less bacterial adhesion and uptake on the device and sustained release of a conditioning agent.

Priority: US20050740534P Applic. Date: 2005-11-29

Inventor: LINHARDT JEFFREY [US]; SALAMONE JOSEPH C [US]; AMMON DANIEL M JR [US]; BORAZJANI ROYA N [US]

Title: Dental releasing materials

Applicant/Assignee: ADA FOUNDATION

Application No.: 11/138182   Filing Date: 26/May/2005

Abstract:

The present invention relates to methods and compositions of dental materials containing nano-sized calcium phosphate and other fillers that release calcium, phosphate and fluoride. This invention further relates to dental compositions for restorations, stress-bearing applications, artificial crowns, anterior and posterior tooth fillings, adhesives, cavity liners, cements, bases, orthodontic devices, prostheses, and sealants utilizing high stress-bearing materials that release materials for the remineralization of decayed tooth structures.

Priority:

Inventor: XU HUAKUN [US]; SUN LIMIN [US]; TAKAGI SHOZO [US]; CHOW LAURENCE C [US]

Title: Self-cure activator

Applicant/Assignee: DENTSPLY RESEARCH AND DEVELOPMENT CORP

Application No.: 11/501342   Filing Date: 09/Aug/2006

Abstract:

A self curing activator for chemical polymerization of the interface of a dental bonding agent and a self curing or dual curing dental cement or restorative, includes an aryl borate compound, a polymerizable monomer, an optional acidic compound, an amine compound which exhibits a catalytic action, an organic peroxide containing material, and a metal compound wherein said metal compound promotes the decomposition of the organic peroxide.

Priority: US2006-351040 Applic. Date: 2006-02-08; US20050651030P Applic. Date: 2005-02-08

Inventor: LIU HUAIBING [US]; HAMMESFAHR PAUL D [US]; POMRINK GREGORY [US]

Title: Cleaning device with pivoting tank

Applicant/Assignee: SHOP VAC CORPORATION

Application No.: 11/294025   Filing Date: 05/Dec/2005

Abstract:

The disclosed cleaning device has a suction unit that can be used to take in liquid, a tank that can be used to hold the liquid, a mouth that can be used to pour liquid from the tank, and wheels that form a base. It also has a pivot that can be used to rotate the tank between a normal use position and a pouring position. The pivot is arranged so that in the pouring position, the center of gravity of the unit remains within the horizontal range of the base, even as the mouth of the tank falls outside the horizontal range of the base. As shown, the pivot is 12 inches above the floor and within the horizontal range of the base. In this position, it remains laterally between the center of gravity of the tank and the edge of the base when the tank is emptied.

Priority:

Inventor: MARTINEZ DAVID [US]; CREVLING ROBERT L JR [US]

Title: Full face respiratory mask with integrated nasal interface

Applicant/Assignee: RIC INVESTMENTS, LLC

Application No.: 11/633888   Filing Date: 05/Dec/2006

Abstract:

A patient interface that reliably and comfortably seals a user's face by providing an oral-nasal mask that includes an integrated nasal interface. The patient interface includes a seal member having an oral cushion portion configured to surround the user's mouth and a nasal interface portion that provides an interface with the user's nose. The seal member, including the oral cushion portion and the nasal interface portion, is a unitary member. Finally, the nasal interface portion remains below the bridge of the nose.

Priority: US20050748311P Applic. Date: 2005-12-07

Inventor: HO PETER C F [US]; EATON JASON P [US]

Title: Water-swellable waterproof sealant

Applicant/Assignee: SANYO CHEMICAL INDUSTRIES, LTD

Application No.: 10/587958   Filing Date: 27/Jan/2005

Abstract:

A water swelling water stop material comprised of a water permeable sheet, characterized in that water absorbent resin particles (A) are enclosed therein so that the water stop material upon water absorption and swelling has the configuration of polyhedron (B). The water stop material is thin to thereby facilitate storage thereof and is lightweight to thereby render carry thereof easy. The polyhedron (B) is so constructed that upon water absorption and swelling, at least two faces are planar. When the polyhedron (B) is formed into a rectangular solid or cube, even if multiple polyhedrons (B) are piled one upon another, they are stable and are resistant to collapse even under the influence of a a large amount of water. When polyhedrons (B) of the same configuration are piled one upon another, any gaps between water stop materials are slight so as to inhibit water leakage through the gaps. Moreover, when the polyhedron (B) has a cavity, the cavity can be packed with a heavy solid material or can have a stake hammered therein so that the water stop material can stably resist violent water streams. Therefore, this water swelling water stop material can be appropriately used as a water stop material for rainwater penetration prevention in order to protect banks, buildings, houses, etc. in the event of flood, heavy rain, etc.

Priority: JP20040024018 Applic. Date: 2004-01-30; JP20040024031 Applic. Date: 2004-01-30; WO2005JP01133 Applic. Date: 2005-01-27

Inventor: KIDA HIROYUKI [JP]; ZENITANI YUKIO [JP]

Title: Footwear packaging

Applicant/Assignee:

Application No.: 10/582458   Filing Date: 08/Dec/2004

Abstract:

A footwear package comprises a flexible bag ( 2 ) or like container of which at least a front is light-transmitting. Closure means ( 23 ) is provided for closing the container. Locating means ( 21 ) is provided for locating items of footwear in the container.

Priority: GB20030028790 Applic. Date: 2003-12-12; WO2004GB05147 Applic. Date: 2004-12-08

Inventor: LEE SIMON L [GB]; POTTER EDWARD W [GB]; NEWLAND PETER J [GB]

Title: ENZYMATIC BLEACHING SYSTEM

Applicant/Assignee:

Application No.: 11/610958   Filing Date: 14/Dec/2006

Abstract:

The present invention relates to a novel enzymatic bleaching system, including at least one oxidase and at least one perhydrolase, body care agents, hair shampoos, hair care agents, mouth-, tooth- or denture care products, cosmetics, therapeutics, textile detergents, cleaning compositions, rinsing agents, textile detergents for automatic washing machines, hand detergents, hand dishwashing agents, automatic dishwasher agents, disinfectants and agents for bleaching or disinfecting filter media, textiles, hides, paper, skins or leather, comprising the novel enzymatic bleaching system, as well as uses of the novel enzymatic bleaching system and this composition.

Priority: DE200410029475 Applic. Date: 2004-06-18; WO2005EP06178 Applic. Date: 2005-06-09

Inventor: STEHR REGINA [DE]; BESSLER CORNELIUS [DE]; MAURER KARL-HEINZ [DE]; WIELAND SUSANNE [DE]; HOVEN NINA [DE]; PRUSER INKEN [DE]

Title: Controlled release compositions comprising nimesulide

Applicant/Assignee: PANACEA BIOTEC LTD

Application No.: 11/545718   Filing Date: 10/Oct/2006

Abstract:

A controlled release composition comprising nimesulide as an active agent formulated as a gastroretentive system, preferably as a solid oral dosage form is provided, wherein the residence time of the active agent is increased in the stomach, duodenum, jejunum or ileum. The present invention also provides process of preparing such dosage form and methods of using such dosage form compositions. The dosage form compositions are preferably administered once-a-day or twice-a-day and are particularly very useful in the prophylaxis or treatment of NSAID indicated disorder(s) such as acute painful conditions like post-operative trauma, pain associated with cancer, sports injuries, migraine headache and the like, or chronic diseases such as arthritis and the like.

Priority: IN1999DE01297 Applic. Date: 1999-09-28; US2003-089020 Applic. Date: 2003-03-27; WO2000IN00094 Applic. Date: 2000-09-27

Inventor: JAIN RAJESH [IN]; JINDAL KOUR C [IN]; TALWAR MUNISH [IN]

Title: Extrapallial fluid of molluscs, methods of obtaining same, formulation and use thereof

Applicant/Assignee: SOCIETE D'INNOVATION ET DE RECHERCHE APPLIQUEE SA(SIERA SA)

Application No.: 10/587968   Filing Date: 14/Feb/2005

Abstract:

The invention relates to a fluid preparation method comprising the recovery of the fluid that is located between the shell and the body of a mollusc. The invention also relates to the liquid obtained using said method, and to the use thereof in the pharmaceutical field, in particular in order to improve cutaneous healing, to regenerate tissues or to promote osteogenesis or bone mineralization. The invention further relates to compositions, particularly pharmaceutical compositions, medical devices or food supplements containing same.

Priority: FR20040001474 Applic. Date: 2004-02-13; WO2005FR00344 Applic. Date: 2005-02-14

Inventor: LOPEZ EVELYNE [FR]; BOURRAT XAVIER [FR]; ROUSSEAU MARTHE [FR]

Title: Method of diagnosis of foot and mouth disease and the diagnostic kit

Applicant/Assignee: PRINCETON BIOMEDITECH CORPORATION

Application No.: 10/555059   Filing Date: 06/May/2003

Abstract:

The present invention provides a method for diagnosing foot-and-mouth disease virus infection, comprising the steps of applying a predetermined amount of a test sample to a loading region of a strip

coupling a detection reagent including a given labeling reagent to an analyte of interest in the test sample to form a complex therebetween

developing the complex onto a wicking membrane

and observing changes in appearance of a reactivity zone having at least more than one immobilized phase selected from antigen, antibody or hapten on the predetermined region of the wicking membrane, derived from FMDV or obtainable from FMDV through an immunological reaction to determine the presence or absence of foot-and-mouth disease virus infection. It also provides a kit for diagnosing foot-and-mouth disease virus infection comprising a strip 1 including a reactivity zone 13 containing at least more than one immobilized phase selected from antigen, antibody or hapten thereon, derived from FMDV or obtainable from FMDV through an immunological reaction, and a control zone 14 for confining normal operation of the kit, provided on a predetermined region of a wicking membrane 9

and a housing 20 protecting the strip 1 from a variety of contaminants, and including at least a test sample application port 2 and an indicia window 4 for observing results of reaction in the reactivity zone 13 and the control zone 14 on the strip.

Priority: KR20030026809 Applic. Date: 2003-04-28; WO2003KR00896 Applic. Date: 2003-05-06

Inventor: CHO IN-SOO [KR]; HYUN BANG-HUN [KR]; LEE KWANG-NYEONG [KR]; OEM JAE-KU [KR]; KYE SOO-JEONG [KR]; KO YOUNG-JOON [KR]; KU BOK-KYUNG [KR]; JOO YI-SEOK [KR]; AN SOO-HWAN [KR]; KIM IN-JOONG [KR]; KIM OK-KYUNG [KR]; KIM HEE-JEONG [KR]; JANG KI-YONG [KR]; SHIN NAM-KYU [KR]; HWANG SUH-HA [KR]; KANG JE-MO [US]; KIM CHANG-HO [KR]; KO SONG-WOO [KR]

Title: Muscarinic acetylcholine receptor antagonists

Applicant/Assignee: GLAXO GROUP LIMITED

Application No.: 10/577834   Filing Date: 04/Nov/2004

Abstract:

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Priority: US20030517243P Applic. Date: 2003-11-04; WO2004US36663 Applic. Date: 2004-11-04

Inventor: WAN ZEHONG [US]; YAN HONGXING [US]; PALOVICH MICHAEL R [US]; LAINE DRAMANE I [US]

Title: Dental compositions comprising disacrylamides and use thereof

Applicant/Assignee:

Application No.: 11/699597   Filing Date: 29/Jan/2007

Abstract:

The invention concerns a dental composition comprising bisacrylamides that are polymerizable by free-radical polymerization and by Michael-addition polymerization with amines. The application of polymerization and addition polymerization with amines opens the possibility to completely reacted materials that have no oxygen inhibited layers. The claimed bisacrylamides have an improved hydrolytic stability.

Priority: US2004-793357 Applic. Date: 2004-03-04; US2002-308564 Applic. Date: 2002-12-03; US2001-925173 Applic. Date: 2001-08-09; US20010310572P Applic. Date: 2001-08-07; US20000224670P Applic. Date: 2000-08-11

Inventor: WALZ UWE [DE]; KLEE JOACHIM E [DE]

Title: Enamel adhesive composition

Applicant/Assignee:

Application No.: 10/588229   Filing Date: 04/Feb/2005

Abstract:

An adhesive resin cement composition having excellent adhesion and physical properties without the application of a priming material or an adhesive when it is bonded to the enamel and aesthetic properties. A photocurable dental enamel adhesive composition comprising (A) a radically polymerizable monomer having an acid group and a structure represented by the following formula (1): CH2-CR<1>-COO-R<2>-OCO-R<3>-COOH (1) (R<1 >is H or CH3, and R<2 >and R<3 >are each independently a divalent inert group essentially composed of C and H), (B) a monofunctional radically polymerizable monomer having a molecular weight of 220 or less and a boiling point of 60 DEG C./10 mmHg or more, (C) a carboxylic ester group-containing aromatic amine, (D) a photopolymerization initiator and (E) a bifunctional radically polymerizable monomer and optionally (F) a filler.

Priority: JP20040030991 Applic. Date: 2004-02-06; WO2005JP02101 Applic. Date: 2005-02-04

Inventor: ZENG WEIPING [JP]; TASHIRO KOICHI [JP]; TANAKA HARUMI [JP]

Title: Method for preparing crosslinked polyelectrolyte multilayer films

Applicant/Assignee:

Application No.: 10/580544   Filing Date: 29/Nov/2004

Abstract:

The invention relates to methods for preparing crosslinked polyelectrolytes, in particular crosslinked polyelectrolytes multilayer films. The invention also relates to a method of coating a surface, and the obtained coated article.

Priority: EP20030292972 Applic. Date: 2003-11-28; WO2004IB04130 Applic. Date: 2004-11-29

Inventor: PICART CATHERINE [FR]; VOEGEL JEAN-CLAUDE [FR]; FRISCH BENOIT [FR]; SCHAAF PIERRE [FR]; DECHER GERO [DE]; CUISINIER FREDERIC [FR]

Title: STEAM FLOOR MOP

Applicant/Assignee: XIAO TIAN (ZHONGSHAN) INDUSTRIAL CO., LTD

Application No.: 11/608819   Filing Date: 09/Dec/2006

Abstract:

The present invention discloses a steam floor mop, comprising a handle

a central body inside which a manual water pump, a water tank, and a steam generator are housed

and a floor brush connected flexibly to the central body, wherein the manual water pump, the water tank, and the steam generator are connected to the floor brush by means of pipes

said handle is connected directly to the piston rod of the manual water pump and serves to manipulate the operation of the manual water pump

said floor brush is covered by a cleaning cloth. In accordance with the steam floor mop of the present invention, by only pushing the handle of the steam floor mop, the steam can be generated and distributed to the floor brush so that the cleaning work having an effect of high temperature disinfecting and sterilization can be realized. It is not needed to power on the water pump additionally so as to supply water to the steam generator to generate the steam. Besides, a plurality of rib stripes are set on the floor brush, and a plurality of steam distributing grooves are formed between the rib stripes, so that the steam can be distributed uniformly to the whole cleaning surface of the floor brush. In addition, the floor brush is covered tightly by a cleaning cloth having a plurality of #-shaped checks formed thereon, so that the stains adhered to the floor can be cleaned easily. Therefore, by utilizing the steam floor mop of the present invention, the cleaning work can be performed conveniently and is time and labor saving, the effect of high temperature disinfecting and sterilization can be realized thoroughly.

Priority: CN20052120479U Applic. Date: 2005-12-10

Inventor: ZHOU HONG [CN]

Title: Apparatus for manufacturing components using electrophoretic deposition

Applicant/Assignee: CEREL (CERAMIC TECHNOLOGIES) LTD

Application No.: 11/313100   Filing Date: 20/Dec/2005

Abstract:

The invention is an apparatus, methods and systems for the production of coatings or small components having defined pre-set dimensions and properties by electrophoretic deposition (EPD) on electrically conducting or semi-conducting substrates. The invention provides efficient and precise mass manufacturing of components by EPD, such as anodes of electrolytic capacitors, by achieving high utilization of expensive raw materials and by consistently achieving tight dimensional tolerances of defined component shapes in repeated depositions. This includes production sequences of discrete components, batches of components, and production by semi-continuous operation.

Priority: IL20050172478 Applic. Date: 2005-12-08

Inventor: THON ASSAF [IL]; BREEN BARRY N [IL]

Title: Conductive polymer

Applicant/Assignee: HERIOTWATT UNIVERSITY

Application No.: 10/575743   Filing Date: 07/Oct/2004

Abstract:

This invention relates to an intrinsically conducting polymer (ICP), a plastics based electrode and a method for making such an electrode. In particular, the plastics based electrode comprises a plastic strip of cellulose acetate acting as a substrate with a thin coating of intrinsically conducting poly (3,4-ethylenedioxythiophene) and poly (4-styrnesulphonate) (i.e. PEDOT/PSS) polymer comprising an amount of vinylacetate/ethylene copolymer. The plastics based electrode may be used in apparatus for the detection of dental caries.

Priority: GB20030023733 Applic. Date: 2003-10-10; WO2004GB04244 Applic. Date: 2004-10-07

Inventor: DANIEL ABRAHAM [GB]; FOTHERINGHAM ALEXANDER F [GB]

Title: Vehicles for oral care with magnolia bark extract

Applicant/Assignee: GIC INNOVATIONS COMPANY

Application No.: 11/602165   Filing Date: 17/Nov/2006

Abstract:

A vehicle and a method for oral care that includes Magnolia Bark Extract in combination with a surface active agent. The effectiveness of Magnolia Bark Extract in inhibiting biofilm formation in the oral cavity is increased by a synergistic combination of the Magnolia Bark Extract with a surface active agent in an oral cavity delivery agent, such as spray, mouthwash, toothpaste, dental cleaner, gel, dental floss, toothpick, dentifrice, and a denture cleaner.

Priority: US20050742363P Applic. Date: 2005-12-02

Inventor: DODDS MICHAEL W [US]; MAXWELL JAMES R [US]; GREENBERG MICHAEL J [US]; TIAN MINMIN [US]