What is described is a high molecular weight homogeneous, branched copolymer of maleic anhydride and a C.sub.1-C.sub.5 alkyl vinyl ether monomer, in which a branching agent is present in an amount of less than 0.5 wt. % of the polymer. A solution process of making such polymer also is described.

Cosmetic composition for use in personal care applications comprising a carrier and a polymeric biguanide, characterised in that the polymeric biguanide is in the form of its salt with an organic acid containing from 4 to 30 carbon atoms.

A method of using of an aralkylalkylsiloxane includes adding the aralkylsiloxane as a component in a personal care composition, in an amount effective to enhance one or more properties, such as shine, lubricity and visual masking of inorganic components, of the personal care composition.

A method for preparing a silicone emulsion, more particularly a method for preparing a silicone emulsion with a low cyclic siloxane level and particle size control.

Aqueous compositions having enhanced thickening properties containing lipophilically modified copolymer thickeners and one or more hydrophilic surfactants are disclosed. In particular, aqueous compositions containing (i) lipophilically modified copolymers containing at least 5% of selected lipophilically modified components and (ii) surfactants having an HLB value of greater than 15 are useful for the thickening of a range of personal, domestic, and industrial products.

An extrudable composition is provided which is made from at least two thermoplastic polymers in a biconstituent construction. One of the thermoplastic polymers is present as a dominant continuous phase and the other one or more polymers are present as a non-continuous phase or phases in an amount of 1.5 weight percent or less. No compatibilizer is necessary. The polymer of the non-continuous phase or phases has a polymer melt temperature higher than 30.degree. C. below the polymer melt temperature of the continuous phase. The polymer of the dominant phase may be, for example, polypropylene and the non-continuous phase may be, for example, polyamide. The extrudable composition may be used to produce fibers which are generally between about 5 and 50 microns in diameter. The fibers may be made into nonwoven fabrics.

The present invention is directed to a novel process of making N-isopropyl acrylamide (NiPAm) polymers based upon the reaction of poly(acrylic acid) and N-isopropylamine. The disclosed method of the present invention uses polyacrylic acid as a starting material to synthesize NiPAm polymers. In one embodiment, the present invention discloses a condensation reaction of an intermediate salt to form homopolymers, copolymers and terpolymers of N-isopropyl acrylamide (NiPAm) with acrylic acid and/or alkyl acrylates in a molten state, which is adaptable to a continuous reactive extrusion process. Binder compositions, water-dispersible products and thermoformable articles containing the NiPAm polymers are also disclosed.

The present invention is directed to a novel process of making N-isopropyl acrylamide (NiPAm) polymers based upon the reaction of poly(acrylic acid) and N-isopropylamine. The disclosed method of the present invention uses polyacrylic acid as a starting material to synthesize NiPAm polymers. In one embodiment, the present invention discloses a condensation reaction of an intermediate salt to form homopolymers, copolymers and terpolymers of N-isopropyl acrylamide (NiPAm) with acrylic acid and/or alkyl acrylates in a molten state, which is adaptable to a continuous reactive extrusion process. Binder compositions, water-dispersible products and thermoformable articles containing the NiPAm polymers are also disclosed.

The present invention is directed to a novel process of making N-isopropyl acrylamide (NiPAm) polymers based upon the reaction of poly(acrylic acid) and N-isopropylamine. The disclosed method of the present invention uses polyacrylic acid as a starting material to synthesize NiPAm polymers. In one embodiment, the present invention discloses a condensation reaction of an intermediate salt to form homopolymers, copolymers and terpolymers of N-isopropyl acrylamide (NiPAm) with acrylic acid and/or alkyl acrylates in a molten state, which is adaptable to a continuous reactive extrusion process. Binder compositions, water-dispersible products and thermoformable articles containing the NiPAm polymers are also disclosed.

A method and apparatus are provided that allows two or more compositions to be filled with a spiral configuration into a single container. Each product may have completely different chemical and physical properties, and each product may have a different function and purpose. The method includes providing at least two compounds, arranged in separate storage bins each having a pump and a hose attached thereto; rotating a container, for receiving a resulting product formed by the at least two compounds, into position relative to a support and alignment funnel; pumping the at least two compounds through the respective hoses into a nozzle assembly having at least two nozzles for filling the container; and combining predetermined amounts of each of the at least two compounds for creating the resulting product housed in a single container, wherein the resulting product has the at least two compounds formed in a spiral configuration.

A method and apparatus are provided that allows two or more compositions to be filled with a spiral configuration into a single container. Each product may have completely different chemical and physical properties, and each product may have a different function and purpose. The method includes providing at least two compounds, arranged in separate storage bins each having a pump and a hose attached thereto and pumping the at least two compounds through the respective hoses into a nozzle assembly while at least one of the nozzle and container rotates with respect to the other; and combining predetermined amounts of each of the at least two compounds for creating the resulting product housed in a single container, wherein the resulting product has the at least two compounds formed in a spiral configuration.

This invention relates to asymmetrical, substituted polysiloxanes which show good compatibility in a variety of oils and improve the spreading behavior of oil-based formulations, to a process for preparing these asymmetrical polysiloxanes and to oil formulations containing said asymmetrical polysiloxanes. The asymmetrical polysiloxanes of this invention are used in herbicidal and pesticidal compositions, in cosmetic and pharmaceutical preparations as well as in industrial applications. The assymmetrical substituted polysiloxanes have the following formula 1 wherein R.sup.1, R.sup.2, Z a and b are described herein.

A preservative system comprising iodopropynyl butyl carbamate and phenoxyethanol at a weight ratio of iodopropynyl butyl carbamate to phenoxyethanol within the range of about 1:90 to about 1:400 shows a broad anti-microbial effect and can permit use of the preservative system at a low level in end use products such as personal care products.

Improved modified monoethanolamide composition mixtures are provided which may be represented by the formula 1 Wherein: R is an optionally substituted or unsubstituted, branched or straight chain, saturated or unsaturated hydrocarbon radical of 3-21 carbon atoms; B is CH.sub.3 or --CH.sub.2--CH.sub.3; and x is at least about 1. wherein the modified monoethanolamide compositions, which are liquid at ambient temperatures or lower, exhibit surfactant properties substantially the same as those exhibited by diethanolamides such as foam stabilization and viscosity building as well as other desirable characteristics.

A disposable, single-use, substantially dry cleansing article is disclosed having wet flexibility, and a lathering surfactant in one embodiment and having an apertured fabric and a specific lather volume coefficient in a second embodiment.

A blend of one or more crosslinked polymers or copolymers prepared from an olefinically unsaturated polymerizable carboxylic or anhydride monomer and at least one high molecular weight essentially linear polymer prepared from an olefinically unsaturated polymerizable carboxylic acid monomer. The blend is neutralized to typically a low pH, and generally contains a noncovalent, e.g. ionic, crosslinking agent, and a cure rate modifier. The hydrogel blend is capable of containing a large amount of water, has good tack, good adhesion, and can be utilized as an application vehicle having a backing thereon as well as containing various substances such as personal care compounds, pharmaceuticals, active ingredients, and the like.

A compatible cosmetic composition for treating keratin substances comprising a cationic guar gum which contains a cationic group selected from the group consisting of amino, ammonium imino, sulfonium or phosphonium groups and wherein the cationic content is represented by a DS of from about 0.25 to 1.0 and an effective surfactant amount of at least one non-ionic or anionic surfactant.

Stable cleansing compositions containing an active agent and a surfactant and further containing ethoxylated solubilizing agents, and a process for stabilizing such compositions.

A blend of one or more crosslinked polymers or copolymers prepared from an olefinically unsaturated polymerizable carboxylic or anhydride monomer and at least one high molecular weight essentially linear polymer prepared from an olefinically unsaturated polymerizable carboxylic acid monomer. The blend is neutralized to typically a low pH, and generally contains a noncovalent, e.g. ionic, crosslinking agent, and a cure rate modifier. The hydrogel blend is capable of containing a large amount of water, has good tack, good adhesion, and can be utilized as an application vehicle having a backing thereon as well as containing various substances such as personal care compounds, pharmaceuticals, active ingredients, and the like.

The present invention is directed to the use of an olfactory acceptable amount comprising tetrahydro-4-methylene-2-(4-methoxyphenyl)-2H-pyran, 5,6-dihydro-4-methyl-2-(4-methoxyphenyl)-2H-pyran, 3,6-dihydro-4-methyl-2-(4-methoxyphenyl)-2H-pyran and mixtures of these materials which are useful in creating fragrances, and scents in items such as perfumes, colognes and personal care products.

Cosmetic or personal care compositions comprise: a hair styling polymer having one or more groups selected from acidic functional groups, anionic groups derived from the acidic functional groups or a mixture of said groups; a partially or fully fluorinated compound having one or more groups selected from amino groups, acid salts of the amino groups or a mixture of said groups, wherein the partially or fully fluorinated compound comprises an aromatic ring; and a cosmetically acceptable diluent or carrier. The compositions are particularly effective under high humidity conditions.

The present invention relates to carbamate group modified polyurethanes and a process for preparing carbamate group modified polyurethanes comprising reacting a polyurethane polymer with an alkylating or an acylating agent. The invention also relates to cosmetic or personal care compositions comprising (i) a styling polymer comprising a carbamate group modified polyurethane and (ii) a cosmetically acceptable diluent or carrier.

Cosmetic and personal care compositions can be manufactured using the multifunctional-additive compositions of the present invention. Such an additive preferably contains one or more particulate-based thickeners, such as a smectite clay, colloidal silica, laponite, and/or alumina, and most preferably one or more smectite clays. According to one important embodiment of the present invention, the thickener particles are co-dispersed with particles of one or more particulate UVR-filters such as titanium dioxide, zinc oxide, or SUNSPHERE (available from International Specialty Chemicals, ISP), and most preferably with the natural particulate sunscreens such as the metal oxides. Another important component of the multifunctional-additive compositions is a dispersant or surface-modifier for the foregoing particulate materials, selected from the family of polyphenolic, natural polymers such as lignosulfonates, lignins, humates, tannates, and derivatives thereof. In addition, these compositions optionally include one or more of the following components: electrolytes, defoamers, humectants, emollients for cosmetics, preservatives, whiteners, and the like.

A resin composition is prepared by reacting components comprising dibasic acid, diamine, polyol and monoalcohol, wherein (a) at least 50 equivalent percent of the dibasic acid comprises polymerized fatty acid; (b) at least 50 equivalent percent of the diamine comprises ethylene diamine; (c) 10-60 equivalent percent of the total of the hydroxyl and amine equilvalents provided by diamine, polyol and monoalcohol are provided by monoalcohol; and (d) no more than 50 equivalent percent of the total of the hydroxyl and amine equivalents provided by diamine, polyol and monoalcohol are provided by polyol. This resin composition may be formulated into, for example, personal care products, fragrance releasing products and candles.

A composition for solubilizing and stabilizing salicylic acid for use in an anhydrous liquid precursor solution for use in the formulation of dermatological, cosmetic, toiletry and personal care products. The anhydrous liquid composition comprises butylene glycol acting as a solubilizer agent being in the range of 5.0% to 30.0% by weight of the composition; glycereth-26 acting as a solubilizer agent being in the range of 40.0% to 70.0% by weight of the composition; and salicylic acid for treating and preventing skin-related problems being in the range of 1.0% to 40.0% by weight of the composition.

A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprision a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.

A method of manufacturing ammonium quat-containing raw material composition with improved transportation efficiency and/or processing properties is provided, including the step of forming a mixture containing the ammonium quat in a solvent that includes at least one glycol and at least one fatty alcohol, wherein said raw material composition has cationic activity of over 35%.

A composition for retaining active ingredients in personal care compositions is described based on one or more polymers having a network structure in an oil phase in amounts from 0.01 to 10% by weight based on the total weight of the composition in the oil phase, the polymers including at least one associative agent, the composition further including at least one active component. The oil phase viscosity of each composition is at least 10 poise under a shear stress up to 1000 dynes/cm.sup.2.

The present invention is directed to an aqueous personal care or cosmetic formulation containing a starch-encapsulated hydrophobic compound. These formulations are stable, and allow for formulations containing hydrophobic ingredients without the need for additional surfactants or emulsifiers. The starch-encapsulated hydrophobic compound is formed by jet cooking a mixture of the starch and the hydrophobic compound. Useful formulations include a wide variety of personal care and cosmetic formulations, including skin and hair care formulations.

The present invention is directed to a cleansing composition containing from about 1% to about 74% by weight of the cleansing composition of a surfactant composition, wherein the surfactant composition further includes from about 5% to about 100% by weight of the surfactant composition of a chelating surfactant; and from about 0% to about 95% by weight of the surfactant composition of a non-chelating surfactant; and from about 1% to about 75% by weight of the cleansing composition of an inorganic or organic salt having divalent metal counterions, wherein, the ratio of the salt to the surfactant composition is from about 0.35 to about 4.0.

Disclosed are stable, liquid broad spectrum preservative formulations comprising (a) an antimicrobial halopropynyl compound and (b) a butoxydiglycol solvent, and optionally (c) (i) an alkanol substituted dialkylhdantoin formaldehyde donor, (ii) an antimicrobial isothiazolone derivative, and (iii) a stabilizer. The invention is also directed to methods of use of the preservative formulations for inhibiting or retarding the growth of bacteria or fungi.

A purified shilajit composition is provided herein from native shilajit. The composition has an abundance of bioactive components, particularly, at least 0.3%, preferably 0.4-1%, by weight, oxygenated dibenzo-.alpha.-pyrones and at least 60%, preferably 65-70%, by weight of fulvic acids of low-to-medium molecular weight ({overscore (M)}n of 700-2000) with an E.sub.4/E.sub.6 ratio of 8-10 at .lambda.465-665 nm, and whose 2% aqueous solution has a pH of .gtoreq.7. Personal care, pharmaceutical and nutritional use formulations of the purified shilajit composition also are described.

This invention relates, in general, to blend compositions of an unmodified poly vinyl alcohol and a thermoplastic elastomer and thermoplastic film and fiber structures comprising these blend compositions. More specifically, this invention relates to substantially water-free films and fibers comprising unmodified polyvinyl alcohol and a thermoplastic elastomer.

A granular composition for use in a personal care product comprises at least one water-insoluble inorganic material having a particle size of no more than 50 .mu.m and up to 10 percent by weight based on weight of water-insoluble inorganic material of a non-binding swelling agent, the granules having a particle size greater than about 50 .mu.m and up to about 1000 .mu.m, as measured by sieve analysis, a dry strength such that from about 20 to about 70 percent by weight pass through a 212 .mu.m sieve when subjected to the attrition test defined herein and a wet strength such that less than 12 percent by weight residue remains on a 45 .mu.m sieve after ultrasonification in water for 1 minute with 48 .mu.m amplitude of vibration, and wherein said granules possess sufficient strength so as not to substantially break down when present in said personal care product.

A water-soluble single-use package for a detergent or personal care composition comprising hydrophobic capsules in the water-soluble body portion. Preferred detergent or personal care compositions are liquid. Preferred capsules are transparent/translucent.

The present invention relates to crystalline and crystal-like forms of lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention relates to methods of purifying lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention also relates to pharmaceutical compositions comprising the purified form of the lipopeptide and methods of using these compositions.

The present invention relates to a topical skin care composition having improved aesthetics containing a skin care active wherein the skin care active is soluble in a tacky solvent and wherein the dermatologically acceptable delivery system contains a tacky solvent in combination with a silicone elastomer and a carrier for the elastomer. The present invention also relates to methods of using such compositions to regulate the condition of mammalian skin while retaining good aesthetics.

The composition comprises (i) one or more ozonised oils and/or one or more synthetic and/or natural ozonised products, and (ii) thioctic acid and/or derivatives thereof, in which each one of the components is found in a concentration lying between 0.01% and 99.99% by weight with respect to the total, and, optionally, one or more active substances, additives, vehicles or excipients. This composition is suitable for the elaboration of pharmaceutical, cosmetic, dietary and food-supplement compositions in human beings and in animals.

Detergent or personal care compositions comprising capsules, which in turn comprise a hydrophobic continuous phase, the latter comprising an isotropic mixture of a thermoplastic-type co-polymer and hydrocarbon oil. Preferably, the capsules further comprise an oil-soluble benefit agent. Preferably, the compositions are liquid, especially aqueous-based compositions. In the preferred embodiment, the capsules are transparent or translucent.

A PCT copolyester composition having at least about 70 mole % terephthalic acid and at least about 70 mole % 1,4-cyclohexanedimethanol and an inherent viscosity of greater than about 0.9 dL/g is prepared by solid state polymerizing a copolyester composition having a starting inherent viscosity of from about 0.4 to about 0.8 dL/g for a period of from about 1 minute to 100 hours and at a temperature of from about 140.degree. C. to about 2.degree. C. below the melting point of the copolyester to produce a copolyester having an inherent viscosity of greater than about 0.9 dL/g. Another aspect of the present invention is an extrusion blow molded article made from the copolyester prepared by the solid state polymerization process.

Concentrated stock composition of capsules for incorporation into detergent or personal care composition, the stock composition comprising a high concentration of capsules comprising a hydrophobic material for forming the capsules, and a supernatant comprising water and a high HLB surfactant and/or a super-wetting agent.

Novel polysaccharides comprising one or more oxime linkages are provided. Methods for their preparation include the polycondensation of saccharides bearing oxime-forming substituents. In some embodiments, polymerization is conducted in the presence of galactose oxidase. The resulting oxime-linked polysaccharides have desirable properties and are useful in numerous applications including paper manufacturing and drug delivery vehicles.

This invention relates to a method of relaxing mammals comprising administering to said mammals a personal care composition which comprises an effective amount of a sensory fragrance that is effective in reducing cortisol levels and/or increasing sIgA levels.

The present invention relates to a dimeric urethane compounds derived from monohydric alcohols, generally fatty alcohols, and a diisocyanate according to the following reaction scheme: 1 wherein R.sub.1 is selected from the group of saturated, unsaturated or halogen substituted linear, cyclic or branch-chained hydrocarbons and R.sub.2 is a linear, cyclic or branch-chained alkyl or aminoalkyl group ranging from two to 200 carbon atoms, preferably two to 50 carbons, more preferably 6 to 36 carbons, even 6 to 24 carbons, said urethane compound being substantially free from terminal hydroxyl groups.

A thickener-rheology modifier system for use in hair care and skin care compositions comprising: a) a hydrophobically modified, alkali-soluble copolymer thickener comprising an aqueous emulsion copolymer of: i) from about 5 to 70 weight percent of .alpha., .beta. ethylenically unsaturated carboxylic acid monomer of the formula: 1 where R is H and R.sup.1 is H, C.sub.1-C.sub.4 alkyl, or --CH.sub.2COOX; R is --COOX and R.sup.1 is H or --CH.sub.2COOX; and R is CH.sub.3 and R.sup.1 is H, C.sub.1-C.sub.4 alkyl or --CH.sub.2COOX; and X is H or C.sub.1-C.sub.4 alkyl; ii) from about 10 to 90 weight percent of a nonionic, copolymerizable, .alpha., .beta. ethylenically unsaturated monomer of the formula: CH.sub.2.dbd.CYZ where Y is H or CH.sub.3 and Z is 2 where R is C.sub.1 to C.sub.4 alkyl; and iii) from about 1 to 30 weight percent of a hydrophobically modified, .alpha., .beta. ethylenically unsaturated carboxylic acid monomer of the formula: 3 where R is an alkyl group of 6 to 22 carbon atoms or an alkaryl of 8 to 22 carbon atom, x is an average number of from about 6 to 200, y is an average number of from about 0 to 50 and A is residue of an unsaturated carboxylic acid having the formula: 4 were R' is H, --COOH or CH.sub.3 and R" is H, CH.sub.3, --COOH or --CH.sub.2COOH; and b) a polysaccharide hydrocolloid or gum or polyalkylene glycol. Preferably the thickener-rheology modifier system will contain a surfactant and more preferably will contain boric acid.

A process for obtaining oils of sesquiterpenes and sesquilactones and (-)-guaiol from the oil of Callitris intratropica, processes for encapsulation of the oil from Callitris intratropica, and the various uses of the oil and the encapsulated oil are described. The oils are suitable for various purposes in the personal care field, e.g. for the antimicrobial treatment of skin, mucosa and hair and of textile fibre materials, as an antimycotic against skin fungi and moulds, as an anti-inflammatory, as an acaricide against house dust mites and ticks, and for preserving cosmetic products.

The present invention is directed to an aqueous polymer composition comprising a copolymer and water, the copolymer containing at least one hydrophilic base or acid-neutralizable monomer and at least one hydrophobic ethylenically unsaturated monomer. A film formed from the contains essentially no crosslinking. The polymer composition is formed by polymerizing the hydrophilic monomer and hydrophobic monomer in a non-aqueous solvent; forming an aqueous polymer dispersion from the non-aqueous polymer solution, and adding a base or acid to form an aqueous polymer composition.

The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of Bacillus amyloliquefaciens subtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a subtitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.

Hair and skin care compositions containing siloxane-based polyamides are disclosed, some of which utilize a base composition comprising a silicone fluid, a silicone immiscible substance, and a siloxane-based polyamide. The siloxane-based polyamide functions as a compatibilizing agent, film forming agent and durability enhancer in these hair and skin care compositions. A method of enhancing the fragrance longevity of fragrance containing skin care compositions after application is also disclosed.

The present invention relates to leave-on compositions for personal care comprising trimethylsilylalkylsilsesquioxanes, particularly trimethylsilyl-n-octylsilsesquioxanes (Caprylyl Trimethicones). Said trimethylsilylalkylsilsesquioxanes are especially useful in formulating emulsions.

The present invention relates to a composition and use of polymeric urethane ester quats as an active ingredient for skin and hair contacting personal care compositions and products related thereto. These compositions are generally produced by the reaction of a trialkanolamine with a hydroxy fatty acid to produce a trialkanolamine fatty acid ester, which is then polymerized with a diisocyanate and in preferred embodiments, further reacted with a quaternizing agent, to produce preferred quaternized compositions according to the present invention.

The present invention is directed to a disposable, single use personal care cleansing product having a water insoluble substrate and from about 2% to about 400% of a composition, by weight of the substrate, comprising, (i) a silicone selected from the group consisting of dimethicone, dimethiconol, and mixtures thereof; and (ii) a lathering surfactant, wherein (i) and (ii) are in a ratio of from about 1:20 to about 5:1, and wherein the composition is combined prior to being added onto or impregnated into the substrate, and wherein the product is capable of generating an Average Lathering Volume of greater than or equal to about 30 ml. The invention also relates to a method of manufacturing such cleansing product as well as a method of manufacturing the skin or hair with the cleansing product.

The present invention relates to polypeptides with reduced immune response including reduced allergenicity having one or more amino acid residues being substituted with other amino acid residues and/or having coupled one or more polymeric molecules in the vicinity of the polypeptides metal binding site, a method for preparing modified polypeptides of the invention, the use of the polypeptide for reducing the immunogenicity and allergenicity and compositions comprising the polypeptide.

Low molecular weight acetal, alcohol, O-acylated alcohol and ester compounds are identified that block the odor of specific carboxylic acids especially propionic acid, butyric acid, isovaleric acid 3-methyl-2-hexenoic acid and hexanoic acid. These compounds exhibit surprisingly high odor blocking properties and are therefore useful additives to compositions such as: a) personal care products including underarm deodorant and antiperspirant, hair shampoo and conditioner, toilet soap, and skin lotion; b) fabric care products including laundry detergents, fabric conditioners, and fabric fresheners; c) pet care products including deodorant, shampoo, conditioner, and d) home care products including air fresheners, carpet fresheners, surface cleaners and hand wash dish detergent.

The invention concerns a process for making personal care compositions and opacifying agents, and corresponding products, having a stable cloudy and milky appearance. The components are processed in a specific sequence in which titanium dioxide is added after thickening agent which comprises a hydrophilic colloid. The composition may, optionally, comprise calcium lactate, calcium lactate salts and combinations thereof. The products, and process, may also comprise the addition of other components such as filler, additives, colorants, cooling agents, warming agents, numbing agents, additional flavorings, active compounds, pharmaceutical actives and excipients or finished bases.

A visually clear and substantially colorless antimicrobial-containing solution comprising at least 20 weight percent of an alkoxylated monoalkanolamide surfactant represented by formula II: 1 wherein: R.sub.1 represents a hydrocarbon radical; R.sub.2 represents a hydrogen atom, --CH.sub.3 or --CH.sub.2--CH.sub.3 radical; and x independently represents at least 1. The antimicrobial-containing solutions are suitable for readily mixing into cosmetics and disinfectant cleaning products.

Isolated and purified nucleic acids encoding green fluorescent proteins from Renilla reniformis and the green fluorescent protein encoded thereby are also provided. Mutants of the nucleic acid molecules and the modified encoded proteins are also provided. Compositions and combinations comprising the green fluorescent proteins and/or the luciferase are further provided.

There are described compounds of formula 1 wherein R.sub.1 and R.sub.2 are each independently of the other hydrogen; unsubstituted or mono- or poly-halo-substituted C.sub.1-C.sub.20alkyl, C.sub.1-C.sub.20alkoxy, C.sub.2-C.sub.20alkenyl, C.sub.2-C.sub.20alkynyl, C.sub.3-C.sub.18cycloalkyl, C.sub.3-C.sub.7cycloalkyl-C.sub.1-C.sub.20alk- yl; hydroxy; C.sub.1-C.sub.6alkoxy-C.sub.1-C.sub.20alkyl; carboxy; C.sub.1-C.sub.6alkyl-oxycarbonyl; cyano; mono- or di-C.sub.1-C.sub.20alky- lamino; C.sub.1-C.sub.6alkylamino-C.sub.1-C.sub.20alkyl; halogen; phenyl; unsubstituted or C.sub.1-C.sub.5alkyl-, halo- or hydroxy-substituted phenyl-C.sub.1-C.sub.20alkyl, phenoxy or phenyl-C.sub.1-C.sub.20alkoxy; or R.sub.1 and R.sub.2 form a polymethylene chain of formula --(CH.sub.2).sub.m--wherein m=2-12; R.sub.3 is unsubstituted C.sub.7-C.sub.20alkyl; or amino-, hydroxy-, carboxy- or C.sub.1-C.sub.6alkyloxycarbonyl-substituted C.sub.2-C.sub.20alkyl; C.sub.8-C.sub.18cycloalkyl; C.sub.8-C.sub.20alkenyl; C.sub.8-C.sub.20alkynyl; C.sub.3-C.sub.7cycloalk- yl-C.sub.8-C.sub.20alkyl; C.sub.1-C.sub.4alkoxy-C.sub.8-C.sub.20alkyl; R.sub.7R.sub.8N-C.sub.7-C.sub.20alkyl; phenyl; phenyl-C.sub.1-C.sub.4alky- l; or phenyl-C.sub.1-C.sub.4alkoxy; R.sub.4 is hydrogen; unsubstituted or C.sub.1-C.sub.5alkyl-, halo- or hydroxy-substituted C.sub.1-C.sub.20alkyl, C.sub.2-C.sub.20alkenyl, C.sub.2-C.sub.20alkynyl, C.sub.3-C.sub.20cycloalkyl, C.sub.3-C.sub.7cycloalkyl-C.sub.1-C.sub.20alkyl, C.sub.1-C.sub.20alkoxy-C- .sub.1-C.sub.6alkyl or R.sub.7R.sub.8N-C.sub.1-C.sub.20alkyl, phenyl, phenyl-C.sub.1-C.sub.20alkyl or phenoxy-C.sub.1-C.sub.20alkyl; R.sub.5 and R.sub.6 are each independently of the other hydrogen; C.sub.1-C.sub.20alkyl; C.sub.2-C.sub.20alkenyl; C.sub.2-C.sub.20-alkynyl; C.sub.3-C.sub.18cycloalkyl; C.sub.3-C.sub.7cycloalkyl-C.sub.1-C.sub.20alk- yl; hydroxy; C.sub.2-C.sub.20alkoxy; C.sub.1-C.sub.6alkoxy-C.sub.1-C.sub.2- 0alkyl; carboxy; C.sub.1-C.sub.6alkyloxycarbonyl; cyano; nitro; C.sub.1-C.sub.20alkylamino; C.sub.1-C.sub.20alkylaminoalkyl; C.sub.1-C.sub.20haloalkyl; C.sub.1-C.sub.20haloalkoxy; halogen; unsubstituted or C.sub.1-C.sub.5alkyl-, halo- or hydroxy-substituted phenyl, phenoxy or phenyl-C.sub.1-C.sub.20alkyl or phenyl-C.sub.1-C.sub.20alkoxy; or R.sub.5 and R.sub.6 together form a polymethylene chain of formula --(CH.sub.2).sub.m--wherein m=2-12; and R.sub.7 and R.sub.8 are each independently of the other hydrogen; C.sub.1-C.sub.20alkyl; C.sub.3-C.sub.20alkenyl; C.sub.3-C.sub.20-alkynyl; C.sub.3-C.sub.7cycloalkyl; C.sub.3-C.sub.20cycloalkyl-C.sub.1-C.sub.4alky- l; phenyl; or phenyl-C.sub.1-C.sub.4alkyl. They are suitable for the antimicrobial treatment of surfaces, as antimicrobial active substances against gram-positive and gram-negative bacteria.

A method of providing a system of providing feedback to a consumer regarding the efficacy of a treatment product prior to the time at which the efficacy is perceivable by ordinary means to a consumer.

The present invention relates to a low amylose tapioca starch crosslinked using mixed adipic and acetic anhydride reagents, and compositions containing such starch. The starch is useful in a wide variety of food, pharmaceutical, and industrial applications to increase the process tolerance of such compositions.

Novel fatty acids and derivatives thereof such as salts, new surfactant systems comprising one or more of these compounds, consumer products such as laundry products, personal care products, pharmaceutical compositions, industrial cleaners, and the like comprising said compounds or surfactant systems.

Compositions comprising chitosan in the form of a network of nano-sized fibres. There is also provided a process for making such compositions. The compositions have improved solubility and activity. The compositions are useful in hair care, skin care, odour control, wound care, blood management, sanitary compositions, oral care, film formation, hard surface treatment, fabric treatment, release of hydrophobic or hydrophilic materials, plant care, water purification and drug delivery.

The present invention relates to a low amylose tapioca starch. Such starch has excellent solution stability, including freeze-thaw stability, and a chain length distribution similar to that of regular tapioca starch. The starch is useful in a wide variety of food, pharmaceutical, and industrial applications, either with or without chemical modification.

A method and apparatus are provided that allows two or more compositions to be placed into a single container in novel designs. Each product may have completely different chemical and physical properties, and each product may have a different function and purpose. The design of the resulting product may be modified by changing factors such as fill speeds, fill durations, the angle of the dispensing nozzle and starting and stopping points of the dispensing.

A moisturizing detergent composition that is mild to the skin and eyes is disclosed. The composition includes a cationic polymer, a monoester emollient, a di-and/or tri-ester emollient and a surfactant. The compositions are useful as shampoos, washes, baths, gels, lotions, creams, and the like.

Alkoxylated esters of dicarboxylic or tricarboxylic acids have an anti-irritating activity measured as a reduction in intracellular leakage of sodium fluorescein of 15% or more at 1:50 dilution or 40% or more at 1:100 dilution from a test composition containing 5% of the alkoxylated ester. These alkoxylated esters are useful in cosmetic and personal care products, especially in products such as baby shampoos, hand dishwashing liquids and bubble bath preparations. A method of reducing irritation provides for application of an irritant with the alkoxylated esters to the subject in a personal care or cosmetic product.

The present invention relates to novel protein variants that exhibit reduced allergenicity when compared to the parental proteins. Also included are DNA molecules that encode the novel variants, host cells comprising the DNA and methods of making proteins less allergenic.

The present invention relates to novel water-in-oil compositions which exhibit unexpected storage stability and other characteristics in a high water content composition. The present compositions comprise a combination of dibehenyl fumarate, PEG 1500 dihydroxystearate and monoethanolamine stearamide (also, stearic monoethanolamide) in combination with an oil and water soluble, and optionally, numerous other ingredients or components. The compositions may be used as an emulsifier mixture, or as emulsions for formulating numerous compositions, and in particular, pharmaceutical or personal care products such as cosmetics and dermatological agents. The compositions according to the present invention are particularly useful as additives in dermatological products, including cosmetic compositions. The compositions exhibit a number of favorable characteristics which are particularly surprising, including one or more of enhanced storage stability, high water content (in certain cases, more than 50% up to about 90% by weight water), high inversion temperature, favorable feel (in certain cases, the compositions which actually exhibit a cooling sensation on the skin), an elegant appearance (shiny and/or smooth) and an ability to be formulated into compositions which are useful for unusual applications.

Disclosed are personal cleansing compositions for rinse-off application to the hair, nails or skin. These compositions comprise a silicone-resin based adhesive including a silicone resin copolymer as a condensation product of an organosiloxane fluid and a silicone resin; a cleansing surfactant; and a carrier liquid. The personal cleansing compositions can also comprise as the silicone-resin based adhesive, in addition to or in place of the silicone resin copolymer, a combination of an organosiloxane resin and a diorganosiloxane fluid at a weight ratio of said resin to said fluid of from about 1:9 to about 10:1. The personal cleansing compositions provide hair styling benefits when applied to the hair, and when applied to the skin, barrier protection from surfactants or other materials having skin irritation potential.

The present invention provides a method for determining the predisposition of an individual to a skin condition comprising identifying the profilaggrin alleles present in the genome of an ex vivo sample taken from the individual. Skin conditions include the ability of an individual to produce Natural Moisturising Factors (NMF), dry skin and/or predisposition to detergent-induced erythema. Typically profilaggrin alleles are identified by determining the number of encoded filaggrin repeats. Methods of the invention are particularly useful for grouping individuals for the purposes of participation in clinical trials or for matching an individual to a cosmetic preparation.

The invention relates to a method for producing protoplasts of cassava or closely related species, which protoplasts are capable of regeneration into plants. The method comprises producing friable embryogenic callus from explants of cassava or closely related species and isolating protoplasts from said friable embryogenic callus. The invention also concerns protoplasts obtainable by said method. The invention further relates to a method for transforming such a protoplast of cassava or closely related species, and transformed protoplasts obtainable thereby. In addition, the invention concerns a method for regenerating plants from these protoplasts and a cassava plant or closely related species obtainable thereby. Starch isolated from tubers of such cassava plants have an increased amylopectin content. The starch and a method for isolating it from said plants also forms part of the invention.

A personal care absorbent article, such as a sanitary pad or napkin, wound dressing, and the like having one or more layers of absorbent material treated with a red blood cell lysing agent and a gelling agent. The effect of combining a lysing agent that thins menses or other blood-containing bodily fluids with a gelling agent that thickens menses or other blood-containing bodily fluids is enhanced agglomeration and increased viscosity of the blood-containing bodily fluids that come in contact with the treated material.

The present invention relates to photo-labile pro-fragrances, as well as a fragrance raw material delivery system comprising: i) from about 0.001% to about 100% by weight, of a photo-labile pro-fragrance compound having the formula: 1 wherein OR is a unit derived from a fragrance raw material alcohol, HOR; R.sup.1 is one or more electron donating groups; each R.sup.2 is independently hydrogen, C.sub.1-C.sub.12 alkyl, and mixtures thereof; X is selected from the group consisting of --OH, --NH.sub.2, --NHR.sup.3, and mixtures thereof; R.sup.3 is hydrogen, C.sub.1-C.sub.12 linear or branched alkyl, C.sub.6-C.sub.10 aryl, and mixtures thereof; and ii) optionally from about 0.001% to about 50% by weight, of one or more fragrance raw materials.

A stable product containing finely a dispersed carotenoid for use in supplementing aqueous systems, such as foods, beverages, and personal care products, with the carotenoid. An emulsifier is dissolved in water and an anti-foam agent and a source of the carotenoid are added to the solution. The concentrated product may be added to the aqueous systems or dried to form a powder that is readily dispersible in aqueous systems. The product may also include an antioxidant to preserve the activity of the carotenoid. Emulsifiers particularly suited for use include sucrose fatty acid esters. The product is produced without the use of organic solvents or elevated temperatures.

A pearlized cleansing composition for personal care comprising: (a) 4.00-30.00 weight % of an anionic material selected from the group consisting of water soluble lipophilic sulfates and sulfonates of 8 to 22 carbon atoms; (b) 0.25-4.0 weight % behenyl alcohol; and (c) water.

A superabsorbent composition comprising a superabsorbent material and an elastomer. The superabsorbent composition has a two-phase morphology resulting in one of the superabsorbent material and elastomer being dispersed as aggregates in the other continuous material. The superabsorbent composition has a low glass transition temperature. The low glass transition temperature gives the superabsorbent composition many beneficial properties. This invention also discloses novel superabsorbent particles, fibers, films, and microporous films. Also disclosed in this invention are personal care articles comprising such particles, fibers, films and microporous films.

The compositions of the present invention relate to personal cleansing compositions having from about 4% to about 50%, by weight, of a surfactant selected from the group consisting of an anionic, cationic, nonionic, amphoteric, and zwitterionic surfactants and mixtures thereof; from about 0.05% to about 10% by weight of a dispersed, water insoluble solid particles or solid, temperature stable particles; from about 0.025% to about 5% by weight of an organic, non crosslinked, cationic homopolymer or copolymer having a cationic charge density of from about 2 meq/gm to about 10 meq/gm and an average molecular weight of from about 1,000 to about 5,000,000; from about 0.1% to about 10%, by weight, of a phase separation initiator selected from the group consisting of electrolytes, amphiphiles and mixtures thereof; and from about 50% to about 95%, by weight, of water.

Silicone oil-in-water emulsions are prepared using a silicone polyether as the surfactant, and the silicone oil-in-water emulsions are stable in an aqueous media in the presence of salts such as electrolytes, alcohols, solvents, and combinations thereof. The silicone oil-in-water emulsions are prepared by (i) polymerizing silicon atom containing monomers in water containing the monomer, a silicone polyether, a catalyst, and optionally an organic surfactant(s), until a silicone oil of a desired molecular weight is obtained. The silicone oil-in-water emulsions possess utility as additives in various coating products, personal care products, household care products, automotive care products, and petroleum products.

The present invention provides a carbohydrate foam composition. The foam composition is highly wettable, resilient and has a uniform pore structure suitable for use in products such as absorbent personal products, health care products, and products suitable for fluid distribution and transfer. The foam of the present invention may also be made into sheets suitable for products such as tissue and paper towels. In one embodiment the foam is made from a carbohydrate and zinc chloride. In a further embodiment the carbohydrate is cellulose, and in a further embodiment the carbohydrate is chitin.

Disclosed are personal cleansing compositions, and corresponding methods of application, wherein the compositions comprise (A) a cleansing phase containing a cleansing surfactant and water; and (B) an active phase containing lipophilic carrier and preferably a skin active agent; wherein the cleansing and active phases are physically separated from one another by one or more packaging barriers, located in the same or separate packages. Preferred embodiments are further defined by selected lipophilic carrier rheologies, defined active phase particulates for improved skin feel, and selected chronic skin active agents for use in the active phase. These compositions and corresponding methods provide improved cosmetics, skin feel, and/or skin active efficacy.

The present invention relates to methods for using amine oxide monomer-containing polymeric suds enhancers (enhancers) to increase the suds and/or foam volume and suds and/or foam retention in suds-forming and/or foam-forming compositions comprising such amine oxide monomer-containing polymeric suds enhancers. Suitable suds-forming and/or foam-forming compositions comprise one or more amine oxide monomer-containing polymeric suds enhancers.

Personal care compositions having excellent shear, shelf and use stability as well as excellent formulation aesthetics (such as skin feel, residue, moisturizing, emolliency, rub-in, absorption and adsorption characteristics, and the like) are made using inverse emulsion polymers having improved electrolyte tolerance and efficiency. The personal care compositions comprise (A) a topically acceptable liquid phase, and (B) at least one electrolyte tolerant inverse emulsion polymer comprising the reaction product of: (1) at least one complex associative monomer having ethylenic unsaturation in an end group, a hydrophilic midsection, and a hydrophobic moiety; (2) at least one pH sensitive monomer having ethylenic unsaturation and at least one carboxylic or sulfonic acid group; (3) an optional copolymerizable non-ionic monomer having ethylenic unsaturation; and (4) at least one crosslinking monomer.

Topical personal care, especially skin care, compositions containing at least one protein and at least one organic powder in an emulsion carrier. Such compositions are useful for providing a skin-tightening effect to the skin while retaining good aesthetics.

The present invention provides a process for the manufacture of a high water content (greater than about 40% by weight of water) cross-linked hydrogel composition which has an acceptable non-greasy "feel", sufficient structural integrity and low brittleness, as well as good processing properties. In the process, a photopolymerisable monomer is photopolymerised, in the presence of water, low levels of a multifunctional photopolymerisable cross-limiting agent (less than about 0.5% by weight of the total polymerisation reaction mixture) and low levels of a photoinitiator (between about 0.002% and about 0.05% by weight of the total polymerisation reaction mixture).

Cosmetic and personal care compositions can be manufactured using the multifunctional-additive compositions of the present invention. Such an additive preferably contains one or more particulate-based thickeners, such as a smectite clay, colloidal silica, laponite, and/or alumina, and most preferably one or more smectite clays. According to one important embodiment of the present invention, the thickener particles are co-dispersed with particles of one or more particulate UVR-filters such as titanium dioxide, zinc oxide, or SUNSPHERE (available from International Specialty Chemicals, ISP), and most preferably with the natural particulate sunscreens such as the metal oxides. Another important component of the multifunctional-additive compositions is a dispersant or surface-modifier for the foregoing particulate materials, selected from the family of polyphenolic, natural polymers such as lignosulfonates, lignins, humates, tannates, and derivatives thereof. In addition, these compositions optionally include one or more of the following components: electrolytes, defoamers, humectants, emollients for cosmetics, preservatives, whiteners, and the like.

Leave-on personal care compositions comprising a stabilized enzyme, at least 30% water, less than 5% of an earth alkali metal salt, and an enzyme inhibitor having an inhibition constant (K.sub.l) from 10 nanomolar (nM) to 25,000 nM. Also, a method of providing a skin care benefits, e.g. skin feel and/or skin appearance, preferably skin moisturization, skin softness, and/or skin smoothness, comprising topically applying a safe and effective amount of the inventive compositions described herein to skin in need of such a skin care benefit. Further, a method of providing a consumer with a leave-on enzyme-containing personal care product, wherein the enzyme is inhibited and inactive on shelf, but is active on skin without the need for a separate re-activation step, preferably wherein the leave-on enzyme-containing personal care product comprises a one of the inventive compositions described herein.

Materials and methods for the detection of microorganisms in a sample by bioluminescence following extraction of microbial ATP, comprises adding a polyol before or during the extraction.

The present invention relates to a surface protection composition comprising a polymer having at least one amide monomer unit, where the amide monomers are free of amine linkages. The invention is also directed to a substrate coated with the solution copolymer. Surfaces that benefit from the protection provided by a coating with the amide polymer include wood, metal, fabrics, textiles, hard surfaces, glass, ceramics, leather, hair and skin. The polymer coating helps prevent fading, and wear, provides UV protection, gives anti-pilling protection and anti-wrinkle in laundry detergent and fabric softener applications, and also provides a vehicle for the controlled release of actives. It is especially useful in protecting hard-surfaces such as glass, ceramic, and tiles.

There are disclosed alkoxysilyl functional silicone based materials that are thermodynamically stable, methods for making them and their uses. The methods comprise cross-linking of reactants that are dispersed in a diluent.

A personal care or cosmetic product composition that includes from about 0.1% to about 99% of at least one ester of alkoxylated aromatic alcohol and fatty carboxylic acid, and from about 0.1% to 60% of at least one functional ingredient is provided. The functional ingredients in the composition may include active ingredients and additional ingredients. Especially suitable active ingredients are sunscreen active ingredients and antiperspirant active ingredients. Preferred compositions are sunscreen product formulations and antiperspirant products. In one preferred embodiment, the composition further includes at least one cyclomethicone compound present in the amount of from about 1% to 99% by weight of the composition. A method of improving the protection of human or animal skin or hair from radiation and a method of improving the protection of human or animal skin or hair from perspiration are also provided.

Described are anti-dandruff and anti-itch compositions comprising: (a) an antidandruff agent; (b) a cooling sensate material; and (c) a cooling sensate. Also described are personal care products for reduction of itching including shampoos, soaps, ointments and creams which contain the anti-dandruff and anti-itch compositions.

The present invention relates to the use of hydroxydiphenyl ether compounds as antimicrobially active substances, to certain new compounds of this type and to processes for the preparation of these compounds.

Polymerized fatty acid-based polyamides may be combined with low polarity and high polarity co-solvents to produce homogeneous water-in-oil emulsions. These emulsions have the appearance of white or translucent creams, with stiffness ranging from soft and greasy, to hard and able to support weight. These emulsions are stable in the presence or absence of surfactant, and are formed easily by mixing components with heat and then cooling. These emulsions are useful in applications favoring an oil base, such as skin creams and cosmetics with emulsions of low stiffness, and car polish with emulsions of greater stiffness.

The present invention relates to topical skin care compositions having improved stability containing a retinoid and a non-paraben preservative and being substantially free of paraben preservatives. Preferred non-paraben preservatives include phenols, phenol salts, carboxylic acids, carboxylic acid salts, quaternium ammonium compounds, halogens, halogen salts, alcohols, inorganic salts, heterocyclic compounds, emulsifying preservatives, and mixtures thereof. The present invention also relates to methods of using such compositions to regulate the condition of skin and/or hair.

Improved methods for the production of multimeric-protein-complexes, such as redox proteins and immunoglobulins, in association with oil bodies are described. The redox protein is enzymatically active when prepared in association with the oil bodies. Also provided are related nucleic acids, proteins, cells, plants, and compositions.

The present invention relates to enzyme variants having decreased immunogenicity relative to their corresponding wild-type enzymes. More particularly, the present invention relates to enzyme variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a substitution of one or more amino acid positions with at least one D-amino acid. The invention further relates to mutant genes encoding such enzyme variants and cleaning and personal care compositions comprising such enzyme variants.

Compositions comprising a stabilized enzyme, at least 30% water, a polyhydric alcohol, present in an amount such that the ratio of polyhydric alcohol to water is from 1:2 to 1:100; less than 5% of an earth alkali metal salt, and an osmo-protectant selected from a certain group of osmo-protectants defined herein. Also, a method of providing a skin care benefits, e.g. skin feel and/or skin appearance, preferably skin moisturization, skin softness, and/or skin smoothness, comprising topically applying a safe and effective amount of the inventive compositions described herein to skin in need of such a skin care benefit. Further, a method comprising providing a consumer with an enzyme-containing personal care product, wherein the enzyme is stable on shelf, and is active on both shelf and skin, preferably wherein the enzyme-containing personal care product comprises one of the inventive compositions described herein.

This invention relates to methods for the stabilization, storage and delivery of biologically active macromolecules, such as proteins, peptides and nucleic acids. In particular, this invention relates to protein or nucleic acid crystals, formulations and compositions comprising them. Methods are provided for the crystallization of proteins and nucleic acids and for the preparation of stabilized protein or nucleic acid crystals for use in dry or slurry formulations. The present invention is further directed to encapsulating proteins, glycoproteins, enzymes, antibodies, hormones and peptide crystals or crystal formulations into compositions for biological delivery to humans and animals. According to this invention, protein crystals or crystal formulations are encapsulated within a matrix comprising a polymeric carrier to form a composition. The formulations and compositions enhance preservation of the native biologically active tertiary structure of the proteins and create a reservoir which can slowly release active protein where and when it is needed. Methods are provided preparing stabilized formulations using pharmaceutical ingredients or excipients and optionally encapsulating them in a polymeric carrier to produce compositions and using such protein crystal formulations and compositions for biomedical applications, including delivery of therapeutic proteins and vaccines. Additional uses for the protein crystal formulations and compositions of this invention involve protein delivery in human food, agricultural feeds, veterinary compositions, diagnostics, cosmetics and personal care compositions.

A method for preparing a product of a protein and carotenoid. The carotenoid is added to a solvent. A source of metal ions and a source of proteins is added. The protein and carotenoid product is extracted from the solution in order to demonstrate binding of the lutein to the proteins. The protein and carotenoid product is substantially soluble in water and increases the ability to add the carotenoid to water-based systems, such as foods, beverages, and personal care products. The protein and carotenoid products are particularly suited for use in human supplements where it is desired to add both the protein and the carotenoid to the diet.

A composition of ferulic acid and ethylguaiacol or vinylguaiacol (preferably as the free compounds, optionally as salts or derivatives) shows synergistic antimicrobial properties and may be used in personal care products.

Disclosed are personal care compositions for topical application to the hair or skin, and corresponding methods of application, said compositions and methods comprising or are directed to a solid polymeric foam containing (A) a solid polymer-containing structurant having a defined water solubility and/or dissolution profile; and (B) an active ingredient comprising a surfactant in a weight ratio of the surfactant to the solid polymer structurant of from about 1:8 to about 10:1, preferably 1:1.6:1 to about 10:1; wherein the solid polymeric foam disintegrates in water in accordance with a Substrate Disintegration Test such that no individual foam pieces remain after disintegration that have a topographical area of more than about 10% of the topographical area of the solid polymeric foam prior to application with water. The disclosed compositions and method provide effective topical delivery of active ingredients from a solid polymeric foam substrate that slowly disintegrates and is rinsed away during prolonged single-use or other similar application, such as showers or baths.

A free-flowing surfactant composition comprising at least one anionic surface-active agent, an alkanolamide, an electrolyte, and water is described. In particular, the composition is a surfactant composition that has free-flowing non-Newtonian shear thinning properties and the ability to suspend components and is stable under at least one freeze/thaw cycle.

The properties of dough or bread can be improved by the addition of a carbohydrate oxidase which can oxidize the reducing end of an oligosaccharide more efficiently than the corresponding monosaccharide, e.g., preferentially oxidizing maltodextrins or cellodextrins over glucose. A novel carbohydrate oxidase having the capability to oxidize maltodextrins and cellodextrins more efficiently than glucose may be obtained from a strain of Microdochium, particularly M. nivale. The amino acid sequence of the novel carbohydrate oxidase has very low homology (<20% identity) with known amino acid sequences.

A liquid personal cleansing composition comprising: (a) a cleansing surfactant comprising: (iii) an acyl sarcosinate; and (iv) an additional cleansing surfactant selected from the group consisting of an anionic surfactant other than the acyl sarcosinate, an amphoteric surfactant, a zwitterionic surfactant, and mixtures thereof; wherein the acyl sarcosinate is contained at a level of from about 40% to about 90% by weight of the total cleansing surfactant, and at a level of from about 4% to about 25% by weight of the composition; and (b) water.

The present invention relates to a one-phase microemulsion that contains an emulsifier system containing a branched alkyl glycoside of the formula (I): R.sub.1OG.sub.n, where R.sub.1 is a branched alkyl group containing 8-16 carbon atoms, G is a saccharide residue and n, the degree of polymerisation, is between 1-5, and optionally a linear alkyl glycoside with the formula (II): R.sub.2OG.sub.n, where R.sub.2 is a linear alkyl group containing 6-18 carbon atoms, G is a saccharide residue and n is between 1-5, a water insoluble oil component, water and, if needed, minor amounts of a cosurfactant/cosolvent. This microemulsion may be used e.g. in a cleaning process for removal of hydrophobic substances from hard surfaces or textile, and in personal care of pharmaceutical formulations.

The present invention provides a silicone derivatized macromolecule that is supported on a particulate support or a separation membrane and method for making that composition. The silicon-derivatized macromolecule can also be combined with chiral ligands or chelated metals. The applications for the silicone derivatized macromolecule variety including use in HPLC separations, in purification process and in personal care formulations.

Cosmetic compositions containing organic sunscreens along with a 4-substituted resorcinol derivatives of general formula I exhibit improved storage stability and oxidative stability: 1 where each R.sub.1 and R.sub.2, independently, represents a hydrogen atom, --CO--R (acyl group), --COO--R CONHR; where R represents saturated or unsaturated, linear, branched or cyclic C.sub.1-C.sub.18 hydrocarbon groups; and R.sub.3 represents (1) an alkyl group, having from 1 to 18 carbon atoms, preferably having from 2 to 12 carbon atoms, with or without substitution of one or more hydrogen atoms of a linear alkyl group with a methyl or ethyl group; e.g., R.sub.3 constitutes linear or branched chain alkyls, or (2) a group of the general formula formula (II) 2 Where X is preferably H, n is 0 to 3 and the dashed lines represents an optional double bond.

Cosmetic compositions containing terpenoids along with a 4-substituted resorcinol derivative exhibit improved storage stability and oxidative stability.

Disclosed is a method of topically applying active ingredients to the hair or skin, said method comprising the steps of: (A) applying to the hair or skin a combination of water and a personal care composition, said composition comprising a high-density solid polymeric foam having an Foam Density of from about 0.23 grams/cm.sup.3 to about 1.20 grams/cm.sup.3, said polymeric foam comprising: (i) a solid polymer structurant; and (ii) an active ingredient comprising a surfactant in a weight ratio of the surfactant to the solid polymer structurant of from about 1:8 to about 10:1; and (B) rinsing the hair or skin with water to disintegrate and rinse-away the high-density polymeric foam such that the disintegrated polymeric foam contains no individual foam pieces having a topographical area of more than about 10% of the original topographical area of the solid polymeric foam prior to application, as determined in accordance with a Substrate Disintegration Test herein. The method provides effective topical delivery of active ingredients from a high-density foam substrate that slowly disintegrates and is rinsed away during prolonged single-use or other similar application.

Mixture of dialkyl immidazoline quats with specified substitution content are provided. In one embodiment, at least a portion of the mixture includes at least one dialkyl immidazoline quat having at least one C.sub.16-C.sub.30 alkyl group; the C.sub.16-30 substitution content of the mixture being from about 10% to about 95% with respect to C.sub.10+ reference substitution range. Methods of making immidazoline quats and quat mixtures, personal care and cosmetic products and formulations that contain the immidazoline quats and quat mixtures, methods of making such personal care and cosmetic products and formulations, and methods of using the such immidazoline quats, quat mixtures, and personal care and cosmetic products and formulations are also provided. Various embodiments are disclosed.

Aqueous free-flowing surfactant compositions having non-Newtonian shear thinning properties are disclosed. These stable compositions include both cationic and anionic surfactants and can suspend water-insoluble particles or partially insoluble components.

There is described the preparation of phenylphenol compounds of formula (I) by reaction of a keto compound of formula (3) with dioxolane of formula (4) and with an ammonium compound of formula (5) to form a .beta.-aminoketone compound of formula (6) (reaction step (I)), reaction of the compound of formula (6) with a compound of formula (7) to form a compound of formula (2) (reaction step (II)), and subsequent alkylation to form a compound of formula (I) (reaction step (III)) in accordance with scheme (A); wherein R.sub.1, R.sub.2, R.sub.3, R.sub.6 and R.sub.7 are each independently of the others hydrogen or C.sub.1-C.sub.8-alkyl; R.sub.4, R.sub.5 and R.sub.8 are each independently of the others hydrogen or C.sub.1-C.sub.5alkyl; and Hal is a halogen atom. The compounds prepared in accordance with the invention are suitable as antimicrobial active substances. 12

The present invention relates to an improved fragrance controlled release system that can be incorporated into anhydrous consumer and cosmetic products such as powder laundry detergents, underarm deodorant or antiperspirant sticks, soap bars, body deodorant powders, foot spray, hygiene sprays, feminine napkin sprays, undergarment sprays, and the like that provides a high intensity odor signal such as a high impact fragrance burst in response to moisture. A selected fragrance is encapsulated in a water-sensitive matrix material. The high impact fragrance burst in response to moisture is achieved by formulating the fragrance or fragrance ingredients that are encapsulated to provide improved fragrance release in response to moisture. The encapsulated fragrance is formulated by combining fragrance ingredients such that their interaction with water results in increasing their relative content in the headspace of the system proximate environment after the system has been exposed to moisture. Examples of suitable fragrance ingredients have ClogP.ltoreq.4.0 and boiling point.ltoreq.300 degrees C. The present invention also can provide multiple fragrance bursts in response to moisture. Multiple fragrance bursts can be achieved by formulating the moisture sensitive matrix material with materials having different dissolution rates. The invention further relates to anhydrous consumer and cosmetic product compositions comprising the improved fragrance controlled release system of the present invention.

Peptide compositions and methods for inhibiting and controlling the growth of microbes using peptides possessing antimicrobial activity are described. The composition comprises at least one antimicrobial peptide in combination with at least one biocide, germicide, preservative or antibiotic. The method comprises administering an amount of the peptide composition effective for the prevention, inhibition or termination of microbes in industrial and clinical settings.

Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

Compositions that include mixtures of (a) at least one dialkyl quat in the amount of from about 10% to about 90% by weight of the composition; and (b) at least one monoalkyl quat in the amount of from about 10% to about 90% by weight of the composition are provided. Various embodiments are provided. In one embodiment, the mixtures include dialkyl immidazoline quats and monoalkyl immidazoline quats. In one embodiment, the mixtures include dialkyl immidazoline quats and monoalkyl ammonium quats. Various methods of making immidazoline quats and quat mixtures, personal care and cosmetic products and formulations that contain the immidazoline quats and quat mixtures, methods of making such personal care and cosmetic products and formulations, and methods of using the such immidazoline quats, quat mixtures, and personal care and cosmetic products and formulations are also provided.

A breathable polyurethane having an upright moisture vapor transmission rate (MVTR) of more than about 500 gms/m.sup.2/24 hr comprises: (a) poly(alkylene oxide) side-chain units in an amount comprising about 12 wt. % to about 80 wt. % of said polyurethane, wherein (i) alkylene oxide groups in said poly(alkylene oxide) side-chain units have from 2 to 10 carbon atoms and are unsubstituted, substituted, or both unsubstituted and substituted, (ii) at least about 50 wt. % of said alkylene oxide groups are ethylene oxide, and (iii) said amount of said side-chain units is (i) at least about 30 wt. % when the molecular weight of said side-chain units is less than about 600 grams/mole, (ii) at least about 15 wt. % when the molecular weight of said side-chain units is from about 600 to about 1,000 grams/mole, and at least about 12 wt. % when the molecular weight of said side-chain units is more than about 1,000 grams/mole, and (b) poly(ethylene oxide) main-chain units in an amount comprising less than about 25 wt. % of said polyurethane. Coatings and films for textiles and other articles and applications using such polyurethanes have excellent breathability, i.e., high moisture vapor transmission rates (MVTR).

A composition and method for protecting personal care components, advantageously labile active personal care components, from decomposition during high temperature drying, employing water-soluble hydrolyzed polysaccharide encapsulants. Also disclosed is an additive for a personal care composition comprising a personal care component that is at least partially encapsulated within a hydrolyzed polysaccharide encapsulant. Also disclosed is a method for protecting a composition containing labile biologically active particles which comprises encapsulating at least a portion of the biologically active particles within hydrolyzed polysaccharide particles, thereby protecting said portion of said biologically active particles.

A personal care composition comprising leghemoglobin and at least one preservative selected from the group consisting of alcohols, glycols, parabens, hydantoins, quaternary nitrogen-containing compounds, isothiazolinones, aldehyde-releasing agents, and halogenated compounds. Preferably, the leghemoglobin is a nitrogen fixation root nodule extract providing a leghemoglobin concentration in the composition of between 0.0001% and about 10% based upon the total weight of the composition. Also disclosed is a method for preparing the personal care composition.

The present invention relates to lathering cleansing compositions that comprise: a) a safe and effective amount of one or more mild crystalline surfactants, b) water, and c) a safe and effective amount of one or more polar solvents (other than water) wherein the composition exhibits hotmelt behavior and is substantially free of additional water soluble crystalline structurants. These hotmelt compositions have been found to be useful for cleansing and conditioning skin and hair due to their ability to achieve a sustained lather and to deposit therapeutic benefit agents. The present invention also relates to personal cleansing articles that comprise a water insoluble substrate that is contacted with the above-described hotmelt compositions.

A polymer produced by polymerizing via water-in-oil emulsion polymerization one or more water soluble monomers with one or more polyalkoxylated monomers wherein said one or more polyalkoxylated monomers contains at least 25 alkylene oxide units and wherein said product demonstrates thermothickening properties, its method of manufacture and use thereof is disclosed.

Cosmetic or personal care compositions comprise from 0.01% to 10% by weight of a hair styling polymer comprising one or more hydrophobic groups, from 0.001% to 10% by weight of an optionally substituted cyclodextrin and a cosmetically acceptable diluent or carrier. The cyclodextrin complexes with the hydrophobic groups to increase the solubility of the hair styling polymer in the composition. The cyclodextrin thus allows the formulation of compositions with relatively higher water contents.

The use of compounds of formula (1) is described, in which compounds R.sub.1, R.sub.2 and R.sub.3 are each independently of the others hydrogen; C.sub.1-C.sub.20alkyl; C.sub.3-C.sub.7cycloalkyl; C.sub.2-C.sub.20alkenyl; C.sub.4-C.sub.7cycloalkenyl; C.sub.2-C.sub.20alkynyl, C.sub.4-C.sub.7cycloalkynyl; or unsubstituted or C.sub.1-C.sub.5alkyl-, C.sub.3-C.sub.7cylcoalkyl-, C.sub.1-C.sub.5alkoxyl-, C.sub.3-C.sub.7cycloakoxy-, halo-, oxo-, carboxy-, carboxy-C.sub.1-C.sub.7alkyl ester-, carboxy-C.sub.3-C.sub.7cyl- cloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C.sub.1-C.sub.20alkylamino- or nitro-substituted phenyl-C.sub.1-C.sub.5alkyl, naphthyl-C.sub.1-C.sub.5alkyl, phenylcarbonyl-C.sub.1-C.sub.5alkyl, naphthylcarbonyl-C.sub.1-C.sub.5alky- l, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl, thiophenyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, 1,2,3-oxadiazolyl, 1,3,4-oxadiazolyl, 1,2,3-thiadiazolyl, 1,3,4-thiadiazolyl, indolyl, pyridyl, pyridazinyl, pyrimidinyl, pyridazinyl, quinolinyl or isoquinolinyl; R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are each independently of the others hydrogen; C.sub.1-C.sub.20alkyl; C.sub.3-C.sub.7 cycloalky; C.sub.2-C.sub.20alkenyl- ; C.sub.4-C.sub.7cycloalkenyl; C.sub.2-C.sub.20 alkynyl; or C.sub.4-C.sub.7 cycloalkynyl; and m and n are each independently of the other 0 or 1, for antimicrobial treatment of surfaces. The compounds exhibit a pronounced activity against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. They are accordingly suitable for the antimicrobial treatment, especially preservation and disinfection, of surfaces.

A reinforced networked polymer/clay alloy composite is produced by contacting a monomer/clay mixture with a reinforcing agent. The monomer/clay mixture comprises a monomer, a cross-linking agent and clay particles. An initiator means is used to initiate polymerization of the monomer/clay mixture, while the cross-linking agent concurrently acts to network oligomeric and polymeric species formed during polymerization to produce a networked polymer/clay alloy in the presence of the reinforcing agent. The networked polymer/clay alloy is intimately integrated with the reinforcing agent such that, on exposure to water, the networked polymer/clay alloy swells with substantially no clay separating from the composite.

Disclosed are multi-purpose alkali-swellable and alkali soluble associative polymers, which are the polymerization product of a monomer mixture comprising: (a) at least one acidic vinyl monomer; (b) at least one nonionic vinyl monomer; (c) a first associative monomer having a first hydrophobic end group; (d) a monomer selected from the group consisting of a second associative monomer having a second hydrophobic end, a semihydrophobic monomer and a combination thereof; and, optionally, (e) one or more crosslinking monomers or chain transfer agents. When monomer (d) is an associative monomer, the first and second hydrophobic end groups of monomers (c) and (d) have significantly different hydrophobic and/or steric character from one another. The multi-purpose associative polymers surprisingly provide desirable Theological and aesthetic properties in aqueous media.

Disclosed are personal care or cosmetic compositions comprising a dicarboxy functionalized polyorganosiloxane and methods for the cleaning or the treatment of hair or skin and for enhancing delivery of active agents to hair or skin with the compositions. Said personal care or cosmetic compositions can be formulated in a wide variety of types of products for the skin and/or hair (or, more generally, keratin) such as mousses, gels (in particular hair dressing gels), conditioners, hair dressing formulations or to aid comb-through of hair, rinsing formulae, hand and body lotions, skin moisturising products, skin cleansing or disinfecting compositions, shower gels, toilet milks, cream foundations, make-up removal compositions, sun and ultraviolet radiation protection lotions, creams or gels, skin care creams, anti-age preparations, anti-acne preparations, local analgesics, mascaras, deodorants, antiperspirants, lipsticks and other compositions of the same type. The use of dicarboxy functionalized polyorganosiloxanes permits to confer benefits such as an increase in shine, gloss or volume of hair, easier comb-through of hair, easier spreadability or slipperiness onto skin; it also permits a better persistence of active materials or benefits agents deposited onto the surface and consequently permits to maintain the activity of the composition deposited on the surface over time. The dicarboxy functionalized polyorganosiloxane can be used in an amount of from about 0.1% to about 30%, preferably from about 3% to about 10% by weight, of said personal care or cosmetic compositions.

Rinsable skin conditioning compositions comprising high internal phase emulsions and being substantially free of surfactant provide superior deposition on skin of conditioning agents, skin benefit agents and/or other conventional cosmetic or skin care ingredients. Such rinsable skin conditioning compositions have much improve aesthetics as well.

Rinsable skin conditioning compositions comprising high internal phase emulsions and being substantially free of surfactant provide superior deposition on skin of conditioning agents, skin benefit agents and/or other conventional cosmetic or skin care ingredients. Such rinsable skin conditioning compositions have much improve aesthetics as well.

The present invention relates to crosslinked protein crystals characterized by the ability to change from insoluble and stable form to soluble and active form upon a change in the environment of said crystals, said change being selected from the group consisting of change in temperature, change in pH, change in chemical composition, change from concentrate to dilute form, change in oxidation-reduction potential of the solution, change in the incident radiation, change in transition metal concentration, change in flouride concentration, change in free radical concentration, change in metal chelater concentration, change in shear force acting upon the crystals and combinations thereof. According to one embodiment of this invention, such crosslinked protein crystals are capable of releasing their protein activity at a controlled rate. This invention also provides methods for producing such crosslinked protein crystals, methods using them for protein delivery and methods using them in cleaning agents, including detergents, pharmaceutical compositions, vaccines, personal care compositions, including cosmetics, veterinary compositions, foods, feeds, diagnostics and formulations for decontamination.

A composition for use as an anti-foam in laundry detergent wherein the anti-foam active ingredient is released slowly throughout the wash and rinse cycle.

Disclosed is a personal care composition comprising by weight: (a) from about 5% to about 35% of a hydrophobic gel comprising: (i) a cholesteryl derivative; (ii) an oil swelling clay material; (iii) a non-volatile liquid oil; and (iv) a polar solvent; and (b) a carrier which is substantially free of water, surfactant, and lecithin; which satisfies the need for a personal care composition having improved physical stability.

The present invention is directed to a sensate composition including at least one cooling sensate, warming sensate and tingling sensate. The tingling sensate is at least one of Jambu Oleoresin and Spilanthol. The present invention is further directed to a method of using the sensate composition in a food, pharmaceutical or personal care product.

Disclosed are aqueous conditioning shampoo compositions which comprise an anionic detersive surfactant component; from about 0.025% to about 5% by weight of an water soluble or dispersible, cationic, non crosslinked, deposition or conditioning polymer; the conditioning shampoo may additionally comprise dispersed, liquid, droplets of a water insoluble, hair conditioning agent having a volume average particle diameter of from about 5 microns to about 125 microns. A homopolymer has a cationic charge density from about from about 2 meq/gm to about 4 meq/gm or a cationic charge density of from about 5 meq/gm to about 10 meq/gm; or an average molecular weight of at least 500,000. A copolymer is formed from one or more cationic monomer units and one or more nonionic monomer units or monomer units bearing a negative charge wherein the subsequent charge of the copolymer is positive. The cationic polymer, in combination with anionic detersive surfactant component and other essential components, provides improved deposition of the conditioning agent on hair or skin, even when the dispersed conditioning agent particles have a volume average particle size of up to about 125 microns. The composition may be applied to skin or hair, and provides improved conditioning performance even without the use of the dispersed hair conditioning agent particles.

A personal care article including an isoprenoid compound, and a method of inhibiting attachment of pathogenic fungi to skin using an isoprenoid compound in combination with a personal care article. The isopreniod compound may be farnesol, which is particularly effective against the pathogenic yeast Candida albicans.

The present invention relates to particle stabilizing compositions suitable for use in fabric care products, home care products, diapers, incontinence articles, feminine care products, pharmaceuticals, oral care products, antiperspirants, deodorants, personal cleansing products, skin care products and hair care products comprising: a) an emulsion comprising from about 1% to about 99% by weight of the emulsion of an internal phase and from about 1% to about 99% by weight of the emulsion of an external phase; b) a charged species that is present in the emulsion; and c) charged insoluble solid particles which are dispersed in the emulsion wherein the charged species possesses a charge which is opposed to that of the charged insoluble solid particles and wherein essentially all of the charged species and charged insoluble solid particles accumulate at the interface of the emulsion and wherein Brownian motion is not exhibited by the charged insoluble solid particles.

Compositions and personal care articles are described comprising a complexed perfume and a coating material which acts to retain the perfume in the complexed state and to keep out other competing materials.

Antimicrobial compositions that provide enhanced immediate and residual anti-viral and antibacterial efficacy against rhinovirus, rotavirus, Gram-positive bacteria, Gram-negative bacteria and combinations thereof. More specifically, antimicrobial compositions comprising an organic acid or organic acid mixture, a specific short-chain anionic surfactant with branching or a large head group, and, optionally, a calcium ion scavenger and/or anti-foam agent. Further, products incorporating the antimicrobial compositions of the present invention and methods of using the antimicrobial compositions and products disclosed herein.

Novel fatty acids and derivatives thereof such as salts, new surfactant systems comprising one or more of these compounds, consumer products such as laundry products, personal care products, pharmaceutical compositions, industrial cleaners, and the like comprising said compounds or surfactant systems.

A resin composition is prepared by reacting components comprising dibasic acid, diamine, polyol and monoalcohol, wherein (a) at least 50 equivalent percent of the dibasic acid comprises polymerized fatty acid; (b) at least 50 equivalent percent of the diamine comprises ethylene diamine; (c) 10-60 equivalent percent of the total of the hydroxyl and amine equivalents provided by diamine, polyol and monoalcohol are provided by monoalcohol; and (d) no more than 50 equivalent percent of the total of the hydroxyl and amine equivalents provided by diamine, polyol and monoalcohol are provided by polyol. This resin composition may be formulated into, for example, personal care products, fragrance releasing products and candles.

Disclosed is a fluid personal care composition comprising calcium silicate and a vehicle, wherein the calcium silicate is capable of absorbing a malodorous compound. These fluid personal care compositions that provide effective, long-lasting suppression of the malodors associated with human perspiration. The personal care composition may be in the form of a solid stick deodorants, liquid roll-on deodorants, aerosol, and pump spray deodorants, semi-solid gel deodorants, soap bars, and deodorant lotions and creams

Antimicrobial compositions that provide enhanced immediate and residual anti-viral and antibacterial efficacy against rhinovirus, rotavirus, Gram-positive bacteria, Gram-negative bacteria and combinations thereof. More specifically, antimicrobial compositions comprising an organic acid or organic acid mixture, a specific short-chain anionic surfactant with branching or a large head group, and, optionally, a calcium ion scavenger and/or anti-foam agent. Further, products incorporating the antimicrobial compositions of the present invention and methods of using the antimicrobial compositions and products disclosed herein.

Novel methods for measuring the soothing attributes of personal care compositions are disclosed. The methods disclosed are particularly suitable for measuring and comparing the soothing attributes of facial tissue to determine which facial tissue is most soothing to damaged skin. The methods include damaging the skin of a test subject to a predetermined amount, contacting a test facial tissue with the damaged skin, and rating the soothing attributes of the facial tissue. In a preferred embodiment, the amount of skin damage on the skin is determined by the test subject.

Elastomeric composites and elastomeric composite laminates including reinforcement strands incorporated into an elastomeric adhesive film. The strands may vary in terms of levels of tension. Facing layers, such as nonwoven webs, can be laminated to both surfaces of the elastomeric composite to form laminates. A method of making such composites and laminates involves adjusting tension among various elastic strands while extruding the elastic strands and incorporating the elastic strands into the elastomeric adhesive film.

Elastomeric adhesive compositions including a high softening point tackifier resin in combination with a base polymer can be used to create laminates having effective adhesion and elastic properties. The compositions may also include a low softening point additive, and/or an antioxidant. Facing layers, such as nonwoven webs and/or films, can be laminated to both surfaces of the elastomeric compositions to form laminates. A method of making such compositions and laminates involves forming the compositions into elastomeric adhesive films.

There are described alkoxybenzylamines corresponding to formula 1 R.sub.1 and R.sub.2 are each independently of the other hydrogen; C.sub.1-C.sub.20alkyl, C.sub.2-C.sub.20alkenyl, C.sub.2-C.sub.20alkynyl, C.sub.3-C.sub.12cycloalkyl, C.sub.3-C.sub.7cycloalkyl-C.sub.1-C.sub.20alk- yl, C.sub.1-C.sub.6alkoxy-C.sub.1-C.sub.20alkyl, C.sub.1-C.sub.12alkoxycar- bonyl, phenyl or phenyl-C.sub.1-C.sub.20alkyl, each of which is unsubstituted or substituted by one or more of hydroxy, halogen, C.sub.1-C.sub.18alkyl, C.sub.1-C.sub.18alkoxy or amino; carboxy; or pyridino-C.sub.1-C.sub.5alkyl; or R.sub.1 and R.sub.2, together with the nitrogen atom linking them, form a 5- to 7-membered monocyclic heterocyclic ring; R.sub.3 and R.sub.4 are each independently of the other C.sub.1-C.sub.20alkyl which is unsubstituted or substituted by one or more of hydroxy, halogen, C.sub.1-C.sub.18alkyl, C.sub.1-C.sub.18alkoxy or amino; and n is 0 or 1. They are suitable for the antimicrobial treatment of surfaces, as antimicrobial active substances against gram-positive and gram-negative bacteria.

This invention relates to a medicament-carrier composition for use in delivering medicaments or fixing the action site of biological active compounds, which mainly comprises a mucoadhesive polymer and a thermoresponsive polymer. The medicament-carrier composition according to this invention is quite suitable for use in topically delivering biological active compounds, especially those useful in photodynamic diagnosis or therapy, e.g. 5-aminolevulinic acid (called as "ALA" for short).

A treatment composition and a method for treating substrates that includes contacting at least a portion of the substrate with (a) an alkyl polyglycoside or a derivative of an alkyl polyglycoside; and (b) a polysaccharide, a modified polysaccharide, a derivative of a polysaccharide or a derivative of a modified polysaccharide is provided. A treated substrate is provided that when used in a personal care product like a diaper and in such a way that the substrate is not in direct contact with skin promotes skin dryness.

Novel insect repellents having ester bonds such that when deposited on skin, natural skin cleaning agents provide slow release of the active.

A fluid storage material including particles, such as superabsorbent particles and/or microencapsulated fragrance agents, cleansing agents, or skin rejuvenation agents, secured to one another and/or secured to a substrate. The fluid storage material can be made by dispersing particles in a crosslinkable binder solution, applying the combined particles and binder solution to a surface such as a substrate or a release surface, inducing crosslinking of the binder, and removing the solvent from the surface such as, for example, by drying the solvent. The fluid storage material is particularly suitable for use in personal care products.

The invention relates to a process for preparing microcapsules by coacervation, wherein the cross-linking of a protein is carried out by a plant extract rich in substituted or unsubstituted phenolic compounds.

The present invention relates to cleansing bars including: a) a cleansing composition; and b) a plurality of discrete elements having a length to diameter ratio of from about 50 to 1 to about 100,000 to 1. The cleansing bars according to the invention have good grippability, exfoliating and cleansing properties and are capable of providing a significant amount of lather in a relatively short period of time. The invention also relates to methods of making and using the cleansing bar described above.

The present invention relates to granules comprising a core matrix and one or more coatings, wherein the core matrix comprises: An active compound, a synthetic polymer, where the amount of polymer added is 0.1 to 10% by weight of the matrix and one or more antioxidants and/or reducing agents, where the amount of antioxidant and/or reducing agent is 0.2 to 5% by weight of the matrix.

A deodorant composition is provided including a phenolic compound, at least one enzyme capable of oxidizing the phenolic compound, and/or a deodorant synergy agent that is either a flavor and a fragrance. The fragrance or the flavor possesses a rating for freshness, cleanness and pleasurableness greater than 50 on a scale of from 1 to 100. Preferably, the fragrance is citrusy, fruity, floral (or flower), musky, minty, green, fresh, woody, sandal, spicy, flower and perilla-type accord. The flavor is preferably citrusy, pepperminty, fruity, juicy, minty, herby, vanilla, spicy, flower and perilla-type accord. A method of deodorizing a mal-odor is also provided which includes mixing the deodorant composition of the present invention with a suitable carrier to form a product for treating mal-odors and applying the product to either an article or a mammal.

Resin modified elastomers, methods of making them and their uses. The method for making the elastomers comprises reacting in a diluent an .ident.SiH functional siloxane; a diene, diyne or ene-yne compound, a resin having the formula (R.sup.1.sub.3SiO.sub.1/2).sub.x(SiO.sub.4/2).su- b.y(R.sup.1SiO.sub.3/2).sub.z where each R.sup.1 is independently a monovalent hydrocarbon group having 1 to 30 carbon atoms or an unsaturated hydrocarbon group having 2 to 30 carbon atoms x is.gtoreq.1, y.gtoreq.0, z.gtoreq.0 and y+z.gtoreq.1.

A personal care composition for topical application to the skin or hair has (i) a branched primary alcohol component, having from about 8 to about 36 carbon atoms and an average number of branches per molecule of from about 0.7 to about 3.0, the branching comprising methyl and ethyl branches, and the branched primary alcohol component optionally having up to about 3 moles of alkylene oxide per mole of alcohol; and (ii) a cosmetically-acceptable vehicle. Advantages of the personal care compositions include, for example, excellent stability, viscosity and rheology characteristics, together with emolliency, application and skin feel benefits.

Disclosed are cleansing compositions comprising one or more surfactants selected from the group consisting of: i) anionic surfactants, ii) amphoteric surfactants, iii) nonionic surfactants, iv) cationic surfactants and v) mixtures thereof, where the dynamic viscosity of the compositions at 25.degree. C. is at least about 100,000 centipoise and where the cleansing composition results in no or minimal eye sting. Also disclosed disposable articles comprising water insoluble substrates releasably containing the cleansing compositions, a process for making the disposable articles and a method of use.

The use of various novel oxime ethers are described as fragrance chemicals. These chemicals are suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products is disclosed.

Disclosed are clear antiperspirant or deodorant compositions that include visible capsules.

A towelette tablet product, which can also be a mask, is provided which includes a water-insoluble web compressed into a tablet form, the web fully extended having a major surface area greater than 10 times a total surface area of the tablet, and a personal care composition formulated into the tablet. When placed into water, the tablet allows the web to open in a fully extended manner. A variety of skin benefit agents formulated into the composition can then be transferred to the skin of a user through contact with the web.

The present invention relates to personal treatment compositions, which contain encapsulated perfume compositions, which release a burst of fragrance a period of time after initial topical application. According to the present invention, the burst of fragrance is released with the application of mechanical pressure on the encapsulated perfume composition. Further, the present invention relates to hair and skin compositions, which release a burst of fragrance a period of time after initial topical application by rubbing the skin or brushing the hair.

The present invention is directed to a sensate composition including at least one cooling sensate, warming sensate and tingling sensate. The tingling sensate is at least one of Jambu Oleoresin and Spilanthol. The present invention is further directed to a method of using the sensate composition in a food, pharmaceutical or personal care product.

A composition which is effective as a skin whitening and skin exfoliation agent. The composition includes one or more hydroxy acids in combination with one or more extracts of one or more jojoba plant parts. The composition further includes Simmondsin. A method of promoting skin whitening and skin exfoliation, comprising the step of topically administering to an individual a composition in an amount effective to whiten and exfoliate skin, where that composition comprises one or more hydroxy acids in combination with one or more jojoba extracts.

Disclosed are multi-purpose polymers that are the polymerization product of a monomer mixture comprising at least one amino-substituted vinyl monomer; at least one nonionic vinyl monomer; at least one associative vinyl monomer; at least one semihydrophobic vinyl surfactant monomer; and, optionally, comprising one or more hydroxy-substituted nonionic vinyl monomer, crosslinking monomer, chain transfer agent or polymeric stabilizer. These vinyl addition polymers have a combination of substituents, including amino substituents that provide cationic properties at low pH, hydrophobic substituents, hydrophobically modified polyoxyalkylene substituents, and hydrophilic polyoxyalkylene substituents. The polymers provide surprisingly beneficial rheological properties in acidic aqueous compositions, and are compatible with cationic materials. The multi-purpose polymers are useful in a variety of products for personal care, health care, household care, institutional and industrial care, and industrial applications.

Novel ester compounds and the use of these esters as a fragrance chemicals, suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products are disclosed.

Compounds of Formula I 1 wherein R, R.sub.1 and R.sub.2 are each independently hydrogen or linear or branched C.sub.1 to C.sub.10 alkyl, or linear or branched C.sub.1 to C.sub.10 alkoxy; R.sub.3 is selected from the group consisting of COCH.sub.3, CO.sub.2R.sub.7, CONH.sub.2, CON(R.sub.8).sub.2, CN, COX(CH.sub.2)n-N--(R.sub.4)(R.sub.5)(R.sub.6), and the quaternized salt form of the formula COX(CH.sub.2)n-N--(R.sub.4)(R.sub.5)(R.sub.6).sup.+Y.- sup.-; X is O or NH; n is an integer of 1 to 5; Y is an anion; R.sub.4, R.sub.5 and R.sub.6 are independently linear or branched C.sub.1 to C.sub.30 alkyl; and R.sub.7 and R.sub.8 are independently hydrogen or linear or branched C.sub.1-C.sub.30 alkyl. Sunscreen formulations containing compounds of Formula I, and methods for protecting hair, skin and substrates such as polymers, textiles, fabrics, leathers and paints using the compounds herein.

Personal cleansing compositions comprise (A) a cleansing phase containing a surfactant and water; and (B) a separate benefit phase containing a hydrophobic material; wherein the cleansing and benefit phases are packaged together and are in physical contact. The two phases are packaged in physical contact and remain separate and stable at ambient conditions for at least 180 days. These compositions and corresponding methods provide improved cosmetics, skin feel, and/or skin benefit efficacy.

There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R.sub.1 is hydrogen; halogen; hydroxy; C.sub.1-C.sub.20alkyl; C.sub.3-C.sub.12cycloalkyl; C.sub.1-C.sub.20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C.sub.1-C.sub.5alkylamino; hydroxy-C.sub.1-C.sub.5alkyl; or phenyl, phenyl-C.sub.1C.sub.20alkyl, phenoxy, phenyl-C.sub.1-C.sub.20alkoxy, naphthyl or naphthyl-C.sub.1-C.sub.20alkyl each unsubstituted or substituted by C.sub.1-C.sub.5alkyl, C.sub.3-C.sub.12cycloalkyl, C.sub.1-C.sub.5alkoxy, C.sub.3-C.sub.12cycloalkoxy, halogen, oxo, carboxy, carboxy-C.sub.1-C.sub.7alkyl ester, carboxy-C.sub.3-C.sub.12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C.sub.1-C.sub.20alkylamino or by nitro; R.sub.2, R.sub.3 and R.sub.4 are each independently of the others hydrogen; C.sub.1-C.sub.20alkyl; or C.sub.3-C.sub.12-Cycloalkyl; R.sub.5, R.sub.6 and R.sub.7 are each independently of the others C.sub.1-C.sub.20alkyl, C.sub.5-C.sub.10aryl, C.sub.1-C.sub.20alkoxy, phenyl-C.sub.1-C.sub.20alkyl, phenyl-C.sub.1-C.sub.20alkoxy, C.sub.2-C.sub.5alkenyl, --O--Si--(C.sub.1-C.sub.5alkyl).sub.3; or O--Si--(C.sub.1-C.sub.5alkyl).s- ub.2-O--Si(C.sub.1-C.sub.5alkyl).sub.3 and n is 0 or 1. The compounds exhibit a pronounced activity against Gram positive and Gram negative bacteria, and also against yeasts and moulds. 1

The present invention provides nonwoven fiber materials, and methods for making the same, useful for loop materials in hook and loop mechanical attachment systems, the nonwoven materials having crimped monocomponent fibers having substantially circular cross sections, and the webs may further contain uncrimped fibers. The invention also provides disposable articles comprising nonwoven loop materials including disposable personal care absorbent articles such as diapers, feminine care sanitary napkins, and adult incontinence articles, and disposable protective articles such as surgical drapes and gowns and other protective apparel.

The present invention relates to methods for using amine oxide monomer-containing polymeric suds enhancers (enhancers) to increase the suds and/or foam volume and suds and/or foam retention in suds-forming and/or foam-forming compositions comprising such amine oxide monomer-containing polymeric suds enhancers. Suitable suds-forming and/or foam-forming compositions comprise one or more amine oxide monomer-containing polymeric suds enhancers.

Personal care compositions that provide improved cleansing and anti-dandruff efficacy. These compositions have from about 5 to about 50 weight percent of a detersive surfactant, from about 0.1 to about 4 weight percent of an anti-dandruff agent, from about 0.1 to about 50 weight percent of a block copolymer of ethylene oxide and propylene oxide with an ethylenediamine core, and at least about 20 weight percent water.

Personal care compositions that provide improved cleansing and anti-dandruff efficacy. These compositions have from about 5 to about 50 weight percent of a detersive surfactant, from about 0.1 to about 4 weight percent of an anti-dandruff agent, from about 0.1 to about 50 weight percent of an octylphenol ethoxylate or nonylphenol ethoxylate, and at least about 20 weight percent water.

An elastic laminate is provided which has an elastic layer and one or two outer facing layers. The elastic layer is formed from an improved styrene-(ethylene-butylene)-styrene-(ethylene-butylene) tetrablock copolymer, or a blend of the copolymer. The copolymer has a number average molecular weight of at least about 70,000. The two ethylene-butylene blocks have number average molecular weights which together constitute more than 75% of the number average molecular weight of the copolymer.

Personal care compositions that provide improved cleansing and anti-dandruff efficacy. These compositions have from about 5 to about 50 weight percent of a detersive surfactant, from about 0.1 to about 4 weight percent of an anti-dandruff agent, from about 0.1 to about 50 weight percent of an octylphenol ethoxylate or nonylphenol ethoxylate, and at least about 20 weight percent water.

The present invention relates to crosslinked protein crystals characterized by the ability to change from insoluble and stable form to soluble and active form upon a change in the environment of said crystals, said change being selected from the group consisting of change in temperature, change in pH, change in chemical composition, change from concentrate to dilute form, change in shear force acting upon the crystals and combinations thereof. According to one embodiment of this invention, such crosslinked protein crystals are capable of releasing their protein activity at a controlled rate. This invention also provides methods for producing such crosslinked protein crystals, methods using them for protein delivery and methods using them in cleaning agents, including detergents, pharmaceutical compositions, vaccines, personal care compositions, including cosmetics, veterinary compositions, foods, feeds, diagnostics and formulations for decontamination.

A personal care composition is provided which includes a fragrance formulated with at least one terpenoid ingredient, a malonic acid salt and a cosmetically acceptable carrier. The malonic acid salt stabilizes the terpenoids against degradation.

Novel ester compounds and the use of these esters as a fragrance chemicals, suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products are disclosed.

The present invention relates to a composition comprising an effective amount of pyrithione or a polyvalent metal salt of a pyrithione and an effective amount of a zinc-containing layered material which provides an augmentation factor greater than 1. The present invention further relates to a method of treating microbial infections, fungal infections, or treating dandruff comprising the use of a composition comprising an effective amount of pyrithione or a polyvalent metal salt of a pyrithione, an effective amount of a zinc-containing layered material which provides an augmentation factor greater than 1.

Novel compositions and methods for reducing odor. The composition comprises at least one synthetic zeolite, at least one acid and at least one substance selected from a metal oxide, metal, or salt of a metal or metal oxide. A wide range of odors, including ammonia and sulfurous odors, may be controlled by contacting an effective amount of the above composition with the article, substance or environment that emits the undesired odor. The composition may also be incorporated into other substances for odor reduction or control to form odor-controlled articles.

New aqueous nacreous concentrated compositions, containing ethoxylated glycerides derived from carboxylic acids having 6 to 22 carbon atoms as emulsifying and/or dispersing agent are provided which show all the essential features required for this kind of composition, such as storage stability, excellent nacreous appearance, besides the possibility of acting as thickening agents and increasing the foaming power of the personal care cosmetic products.

Novel ester compounds and the use of these esters as a fragrance chemicals, suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products are disclosed.

A multi liquid phase composition wherein said phases are visually distinctive. These compositions combine multiple phases for creating multipurpose personal care compositions.

Disclosed is a polyol-in-silicone emulsion consisting essentially of: (i) an alkyl dimethicone copolyol having an HLB of from about 4 to about 6, and a molecular weight of from about 10,000 to about 20,000, wherein the alkyl group is made of about 10 to about 22 carbons; and (ii) a polyol, wherein the weight ratio of the alkyl dimethicone copolyol to the polyol is from about 100:1 to about 2:8; methods to make such a polyol-in-silicone emulsion, as well as an anhydrous personal care composition comprising by weight: (a) from about 0.01% to about 15% of an alkyl dimethicone copolyol having an HLB of about 4-6, and a molecular weight of from about 10,000 to about 20,000, wherein the alkyl group is made of about 10 to about 22 carbons; (b) from about 0.01% to about 35% of a polyol, wherein the weight ratio of the alkyl dimethicone copolyol to the polyol is from about 100:1 to about 2:8; and wherein the composition is substantially free of water.

Personal cleansing compositions contain solid anionic particles. More specifically, personal cleansing compositions contain solid anionic particles and a cationic polymer, wherein the anionic particles are complexed with the cationic polymer to form aggregates prior to mixing with the remaining ingredients and wherein the aggregates are present in the finished product. The personal cleansing products can be used to cleanse human skin, hair and nails.

The invention provides methods for the treatment of diseases and conditions mediated by increased phosphorylation, such as inflammation and cancer. The invention also provides methods for the inhibition of increased phosphorylation in cells, tissues and organs. The methods utilize a phosphate acceptor compound (PAC). The invention also provides products comprising a PAC.

The present invention relates to personal care compositions containing interference pigments, a dispersed oil phase and a continuous aqueous phase. Preferably, the interference pigments are hydrophobically modified interference pigments. The inventors have found that hydrophobically modifying the pigments significantly improves the deposition of the particles on skin from rinsable compositions.

The present invention relates to multi-phase personal care composition containing at least two visually distinct phases wherein at least one phase contains a particle. The phases form a pattern and are packaged in physical contact while remaining stable over time.

The present invention relates to a personal care composition that contains a rinse-off composition which deposits at least 0.5 .mu.g/cm.sup.2 of shiny particles on the skin. Preferably, the shiny particles are hydrophobically modified interference pigments. The inventors have found that hydrophobically modifying the particles significantly improves the deposition of the particles on skin from rinsable compositions.

Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

Systems are provided for the controlled release delivery of active agents through the use of repeat sequence protein polymers. The systems may exist as matrices, gels, hydrogels, films, emulsions or microparticles and are particularly useful for incorporating active agents into personal care product compositions.

The present invention provides a mechanically robust, water-soluble or water dispersible, low-dust granule comprising an active ingredient, a polymer coating, and an impregnated plasticizer within the granule, and methods for obtaining the same.

The present invention relates to a personal care composition containing a dispersed oil phase, a silicone elastomer and an aqueous phase. These compositions are rinsable and at the same time deposit oil and silicone elastomer onto all keratinous surfaces while providing improved skin feel. Additionally, the present invention relates to a method of using a rinse off personal care composition that contains an elastomer gel, a dispersion phase and an aqueous phase.

The compositions of the present invention relate to personal cleansing compositions having from about 0.01 to about 5 wt. % of a cationic guar polymer; from about 5 to about 50 wt. % of an anionic surfactant system, having a specific ethoxylate level and sulfate level to optimize performance of the polymer, from about 0.01 to about 5 wt. % of a mono or divalent salt; from about 0.01% to about 10% of a microemulsified conditioning oil and at least about 20 wt. % of an aqueous carrier.

The compositions of the present invention relate to personal cleansing compositions having from about 0.01 to about 5 wt. % of a cationic guar polymer; from about 5 to about 50 wt. % of an anionic surfactant system, having a specific ethoxylate level and sulfate level to optimize performance of the polymer, from about 0.01 to about 5 wt. % of a mono or divalent salt; from about 0.01% to about 10% of a microemulsified conditioning oil and at least about 20 wt. % of an aqueous carrier.

The present invention relates to a composition and use of polymeric urethane esters quats as an active ingredient for skin and hair contacting personal care compositions and products related thereto. These compositions are generally produced by the reaction of a trialkanolamine with a hydroxy fatty acid to produce a trialkanolamine fatty acid ester, which is then polymerized with a diisocyanate and in preferred embodiments, further reacted with a quaternizing agent to produce preferred quaternized compositions according to the present invention.

The present invention relates to method of using a rinsable personal care composition containing shiny particles and a skin compatible oil phase. Preferably, the shiny particles are hydrophobically modified interference pigments. The inventors have found that hydrophobically modifying the particles significantly improves the deposition of the particles on skin from rinsable compositions.

Biomolecular conjugates are provided which comprise the conjugation product of a repeat sequence protein polymer and at least one active agent. Additional aspects provide methods for their manufacture and various industrial and consumer applications.

Personal cleansing compositions that comprise (A) a cleansing phase containing a surfactant and water; and (B) a separate benefit phase comprising at least one high internal phase emulsion; wherein the cleansing and benefit phases are packaged together and are in physical contact. These compositions and corresponding methods provide improved cosmetics, skin feel, and/or skin benefit efficacy.

The present invention relates to highly compatible hydroxyphenyltriazine UV-absorbers and to their use in protecting plants in green houses and the protection of foodstuffs, beverages, pharmaceuticals, cosmetics, personal care products, shampoos and the like from the deleterious effects of ultraviolet radiation. It has been found that certain highly compatible tris-arly-s.triazines are especially effective towards this end when incorporated in the containers or films in which such materials are stored.

There are described personal care compositions containing a) one or more dibenzoylmethane sunscreening agents; and b) a photostablising amount of a salicylate ester of formula (1): (2-OH)Ph-(CO)--O--R, wherein R represents an alkyl group consisting of a chain of from 7 to 16 carbon atoms substituted by at least one group selected from methyl and ethyl. The compound of formula (1) is preferably isodecyl salicylate or isotridecyl salicylate. The salicylate esters of formula (1) have a stabilizing effect on the compositions. The salicylate esters prevent or inhibit degradation of the sunscreening agents which would otherwise lead to a reduction in the efficacy of the sunscreening agents and an increase in the deleterious effects of exposure to sunlight on the user of the compositions or on the compositions themselves.

The invention provides personal care products that do not contain D4 and/or D5 cyclomethicones but which do have the skin feel, spreadability, and other physical and chemical characteristics of personal care products that do contain these cyclomethicones. The products of the invention include a neopentyl polyol polyester(s) derived from neopentyl glycol, an isoparaffin(s), and a personal care formulation. Also included are replacement compositions for use in personal care products (so that D4 and D5 cyclomethicones can be excluded from the formulation) and methods of preparing personal care products and replacement compositions.

Enzymes mediating in the release of compounds characteristic of human malodour and in particular axillary malodour, and compounds that inhibit said enzymes having the general formula (I) 1

The article contains a fibrous, non-woven web and having a personal care composition associated with this web. The present invention relates to disposable, personal care articles useful for cleansing and/or treating the skin, hair or other similar keratin-containing surfaces. These articles are used by the consumer by either wetting the dry article with water and then rubbing the article against the skin, hair or other similar keratin-containing surfaces, or taking a wet, disposable, personal care article and rubbing against the skin, hair or other similar keratin-containing surfaces or taking a moist, disposable, personal care article and rubbing against the skin, hair or other similar keratin-containing surfaces.

This invention relates new and improved processes for the preparation of arylalkylsulfonic acids derived from aromatic or substituted aromatic molecules and AOS acid (generally a mixture of alkenesulfonic acid and sultones, produced from the sulfonation of alpha olefins) and to cleaning compositions comprising said arylalkylsulfonic acids. The invention involves the use of a superacid catalyst to effectuate the conversion of AOS acid and aromatic reactants to arylalkylsulfonic acid under substantially anhydrous conditions, whereby a substantial improvement in the rate of conversion of the reactants to arylalkylsulfonic acid and/or improvement in mono-alkylation selectivity is realized, as compared to methods of preparation previously disclosed. Also useful as an alkylation promoter is the arylalkylsulfonic acid reaction product itself, produced in situ or from a previous reaction (i.e., a self-catalyst heel). The new processes generally afford arylalkylsulfonic acids with substantially improved conversion yields, highly desirable lighter color, and reduced odor, as compared to previously known methods. The acids produced by the inventive process may be neutralized to form arylalkylsulfonates (i.e., a neutralized form of the acid) which are useful in a variety of end use applications as surfactants and/or emulsifiers.

Photostable broad-spectrum organic sunscreen compositions comprising a UV-A sunscreen, such as Avobenzone, a photostabilizer, a UV-B liquid organic sunscreen, and a solubilizer and further enhancing the photostability by encapsulation using a sol-gel process.

Personal cleansing compositions, comprise (A) a cleansing phase containing a surfactant and water; and (B) a separate benefit phase comprising at least one water in oil emulsion; wherein the cleansing and benefit phases are packaged together and are in physical contact. The two phases are packaged in physical contact and remain separate and stable at ambient conditions for at least 180 days. These compositions and corresponding methods provide improved cosmetics, skin feel, and/or skin benefit efficacy.

A package to protect a plurality of dry articles during use in a wet environment comprises: a) a contaminate reducing access element; and b) a water repellant chassis. The package is designed such that contamination of the dry articles remaining in the package is reduced during removal of articles for use in the wet environment.

Alkylated amine functional macromolecules, ammonium salt functional macromolecules, and quaternized ammonium salt functional macromolecules that are bonded to solid substrates, processes for their preparation, and methods for their use in liquid chromatography, process stream purification, waste stream clean up, resource recovery and personal care products, among other uses.

The present invention is directed to a disposable article that contains a plurality of substrate layers where at least one of the layers is an extruded low density foam and the article has a cleansing composition associated with the substrate layers. The article provides effective cleansing benefits to the skin and hair in a convenient, inexpensive, and sanitary manner. The article of the present invention also has superior thickness. The article has increased rigidity while at the same time is flexible. The increase in rigidity and thickness provides for an article that does not crush or crumple during use. The low density provides for an article that has improved handleability and reduced scratchy feel against the skin. The article of the present invention can also provide a therapeutic or aesthetic benefit without the need for a separate benefit providing product.

The present invention is directed to a disposable article that contains a plurality of substrate layers. The article is selected from the group consisting of pad sized articles, grip sized articles, sheet sized articles and combinations. These articles have a cleansing composition associated with the substrate layers. The articles provide effective cleansing benefits to the skin and hair in a convenient, inexpensive, and sanitary manner. The articles of the present invention also have superior thickness. Additionally, the article has increased rigidity while at the same time is flexible. The increase in rigidity and thickness provides for an article that does not crush or crumple during use. The article of the present invention can also provide a therapeutic or aesthetic benefit without the need for a separate benefit providing product.

The present invention relates to a dual performance cleaning article, wherein said article is comprised of a first abrasive meltblown surface that facilitates the process of loosening particulates, such as dust and dirt, and an opposing second soft, air permeable surface, which is capable of absorbing and/or picking up particulates and liquids. The meltblown layer comprises coarse discontinuous filamentary elements, formed from adjusting the variable commonly utilized in the traditional meltblown method.

The present invention is directed to a method of forming a nonwoven cleaning article, which exhibits a first three-dimensional image and a second three-dimensional image whereby the first and second three-dimensional images are dissimilar from one another. In particular, the present invention contemplates a fabric comprised of sequential three-dimensional images that are formed from a pre-entangled precursor web entangled on a first three-dimensional transfer device so as to impart a first image therein, then subjected to hydroentanglement on a second three-dimensional image transfer device wherein a second three-dimensional image is imparted to the web that is different from the first three-dimensional image, the resulting nonwoven cleaning article presenting aesthetic and tactile qualities representative of both imparted images.

The present invention relates to a dual performance cleaning article, wherein said cleaning article is comprised of a first abrasive meltblown surface that facilitates the process of loosening particulates, such as dust and dirt, and an opposing second soft, air permeable surface, which is capable of absorbing and/or picking up particulates and liquids. The meltblown layer comprises coarse discontinuous filamentary elements, formed from adjusting the variable commonly utilized in the traditional meltblown method.

Perfume compositions comprising defined high impact accords and personal cleansing compositions, especially soap bars, comprising those perfume compositions are provided. In a preferred aspect, the perfume compositions are encapsulated in starch or the like so as to release fragrance when exposed to water, such as in the shower.

An active or functional organic compound is solubilized in a phenylethyl ester, e.g. an aryl carboxylic ester of 2-phenylethyl alcohol, as a solvent, cosolvent or additive, to form a composition thereof. Representative active or functional organic compounds include personal care products, e.g. sunscreens containing UVA/UVB absorbing compounds, such as avobenzone and benzophenone-3. Such compositions also show increased critical wavelength and UVA/UVB absorbance ratio performance properties.

An antibacterial personal care composition comprising at least one surfactant and at least one pH modifier said composition having a pH in the range of from 3.5 to 6.0. The composition further comprises at least one cationic polymer such that the composition is selectively active against transient bacteria relative to resident bacteria.

The present invention provides novel fragile nutrient cochleates that generally include one or more encochleated fragile nutrients, e.g., beta carotene, and methods for making the same. Also provided are methods for the use and administration of the fragile nutrient cochleates of the invention.

The immobilization of organic molecules, telomers and polymers on solid substrates. Organic molecules, telomers and polymers are immobilized onto solid substrates, especially particulate materials via covalent bonds that provide greater thermal and organic stability than other methods of immobilization.

The present invention relates to photo-labile pro-fragrances, as well as a fragrance raw material delivery system comprising: i) from about 0.001% to about 100% by weight, of a photo-labile pro-fragrance compound having the formula: 1 wherein OR is a unit derived from a fragrance raw material alcohol, HOR; R.sup.1 is one or more electron donating groups; each R.sup.2 is independently hydrogen, C.sub.1-C.sub.12 alkyl, and mixtures thereof; X is selected from the group consisting of --OH, --NH.sub.2, --NHR.sup.3, and mixtures thereof; R.sup.3 is hydrogen, C.sub.1-C.sub.12 linear or branched alkyl, C.sub.6-C.sub.10 aryl, and mixtures thereof; and ii) optionally from about 0.001% to about 50% by weight, of one or more fragrance raw materials.

Disclosed is a composition of a functionalized polyalphaolefin comprising the reaction product of admixing (a) an alpha-olefin monomer having at least 10 carbon atoms; (b) an unsaturated functionalizing compound; and (c) a polymerization initializer, under reaction conditions sufficient to polymerize the alpha-olefin monomer and unsaturated functionalizing compound. Free radical initiators, especially peroxides are disclosed to be useful in preparing the functionalized polyalphaolefin. The functionalized polyalphaolefins are disclosed to be useful in preparing inks, toners, coatings, candle waxes, lubricating oils, and personal care products.

The invention concerns solid shaped detergent compositions comprising 0.5-95% by weight detergent active and 0-90% by weight of inorganic particulates and/or other conventional ingredients and wherein the external surface of said shaped detergent composition comprises at least one polymer film obtained by radiation curing or a radiation-curable resin composition.

An active or functional organic compound is solubilized in a phenylethyl ester, e.g. an aryl carboxylic ester of 2-phenylethyl alcohol, as a solvent, cosolvent or additive, to form a composition thereof. Representative active or functional organic compounds include personal care products, e.g. sunscreens containing UVA/UVB absorbing compounds, such as avobenzone and benzophenone-3. Such compositions also show increased critical wavelength and UVA/UVB absorbance ratio performance properties.

A new composition of matter is provided comprising negatively charged polysaccharides which can be derived from Aloe vera and a process to prepare that composition of matter by sub fractionation of an extract of Aloe vera, passing the formed subfraction over a positively charged column and eluting the same with a salt solution. Optionally the Aloe vera is pre purified over a Sephadex G-25 column. This composition of matter and also the extract comprising the same which is formed after pre purification or ultra filtration of an Aloe vera extract is useful as a food supplement or in dietary foods, for use in personal care and in cosmetics, especially to prevent an infection with the bacteria Helicobacter pylori, Pseudomonas aeruginosa, Streptococcus mutans or Streptococcus sanguis.

A structured surfactant composition containing one or more branched alkyl (ether) sulfates according to the formula: RO(CH.sub.2CH.sub.2O).sub.nSO.- sub.3M, wherein R is branched (C.sub.8-C.sub.18)alkyl or branched (C.sub.8-C.sub.18)alkenyl, n has an average value of from 0 to about 7 and M is a solubilizing cation, provided that M cannot be sodium if n is greater than or equal to 1, and a structurant, wherein the composition exhibits non-Newtonian shear thinning viscosity and is capable of suspending insoluble or partially insoluble components

The present invention relates to photostable compositions that provide protection from ultraviolet radiation ("UVR"). The invention particularly relates to the sunscreens avobenzone, octocrylene and oxybenzone, forming a triplet sunscreen combination. Compositions of the present invention are generally substantially free of substantial amounts of other sunscreens. The triplet combination surprisingly provides and substantially maintains the initial SPF value of the sunscreen composition throughout the period of UVR exposure. Compositions of the invention are photostable such that each of sunscreen active in the triplet combination does not appreciably photodegrade. The present invention accurately communicates the amount of UVR photoprotection actually provided in natural sunlight and minimizes the amount of potential harmful free radicals formed as byproducts of photodegradation.

The present invention is directed to a method of making a nonwoven cleaning article, which exhibits a plurality of three-dimensional images whereby the fabric is comprised of at least a first and second three-dimensional image that are dissimilar from one another. The three-dimensional images may be imparted into the fabric in a co-planar arrangement, multi-planar arrangement, or by utilizing both arrangements within the same fabric. Further, the present invention contemplates a cleaning article comprised of a plurality of three-dimensional images which can provide the fabric with various physical and/or aesthetic performances.

The invention relates to an emulsifier combination which is free from ethoxylated emulsifiers, contains less than 20% by weight water and comprises C.sub.8-14 alkyl oligoglycoside, polyol polyhydroxystearate and C.sub.6-22 acyl glutamate. The emulsifier is suitable for the production of nanoemulsions by conventional cold/cold or hot/hot processes. The invention also relates to a process for the production of the emulsifier combination and to wipes coated with the nanoemulsions.

This invention relates to cationically derivatized polycalactomannans obtained from cassia tora and cassia obtusifolia and to their use in personal care, household care, and institutional care compositions.

In a first aspect, personal care compositions are provided comprising oil-in-water emulsions, the emulsions comprising defined water-soluble emulsification polymers. In a second aspect, a method of manufacture of the personal care compositions according to the first aspect is provided.

The use of salicylate compounds as a fragrance chemical, suitable for use in creating fragrance in items such as perfumes colognes and personal care products is disclosed.

In a first aspect, the invention concerns oil-in-water emulsions comprising defined water-soluble emulsification polymers and having an oil phase comprising polar oils. In a second aspect, products, such as cosmetic products, are provided, comprising the emulsions. In a third aspect, a manufacturing method is provided for making the products.

A stable product containing an aqueous solution of one or more carotenoids for use in supplementing aqueous systems, such as foods, beverages, dietary supplements, and personal care products, with the carotenoid. An ester is dissolved in water and a source of the carotenoid is added to the solution. The concentrated product may be added to the aqueous systems or dried to form a powder that is readily dispersible in aqueous systems. The product may also include an antioxidant to preserve the activity of the carotenoid. Esters particularly suited for use include sucrose fatty acid esters. The product is produced without the use of organic solvents or elevated temperatures. The particles of carotenoids dispersed in the liquid form of the product will pass through a 0.2 micron (.mu.m) sterile filter.

A high concentration, aqueous liquid surfactant composition is disclosed, comprising at least one amphoteric or anionic surfactant and a liquid-stabilizing amount of at least one liquid-stabilizing agent. The liquid-stabilizing agent is a succinic acid derivative, glutaric acid derivative or a combination thereof. The composition is pourable and pumpable at ambient room temperature.

Cosmetic or personal care compositions comprise: gelled particles, wherein the gelled particles comprise water and at least 80% by volume of the particles have an aspect ratio of at least 2 and a maximum width of 100 .mu.m; and at least one cosmetically acceptable material selected from surfactants, hair conditioning agents, perfumes or fragrances and hair styling polymers. The compositions may be hair treatment compositions and the gelled particles can be employed to deliver hair benefit agents and to impart desirable textural properties to the compositions.

Breathable laminates of a film and nonwoven with increased toughness and the ability to undergo strain without splitting for applications as components of personal care products and other uses. The film is formed using a carrier/letdown resin approach where the filled carrier resin is an ethylene polymer or copolymer having a density at least 0.003 g/cc higher than the letdown resin which is also an ethylene copolymer but has a density in the range of less than about 0.915 g/cc and a melt index less than about 6. The resin phases may be dry blended, formed into a film, stretched and bonded to a nonwoven support layer.

The present invention relates to fragrance- or odorant-laden polymer capsules and processes for producing the same.

The present invention relates to a process for preparing dry polymer granules, particles and powders having increased minimum ignition energy, lowered to unchanged maximum explosion pressure, lowered explosion strength (Kst) coupled with reduced dusting levels by coagulating one or more emulsion polymers using one or more cationic surfactants including one or more other coagulating agents, filtering the coagulated slurry and drying the coagulated slurry.

The present invention relates to a process for preparing dry polymer granules having increased minimum ignition energy, lowered to unchanged maximum explosion pressure, lowered explosion strength (Kst) coupled with reduced dusting levels by drying a mixture including one or more emulsion polymers and one or more surfactants having HLB values between 10 and 25.

A thermoplastic elastomer film includes a thermoplastic elastomer and a filled semi crystalline predominantly linear polymer. The film includes between about 25 and 70 weight percent filler, between about 5 and 30 by weight percent semi-crystalline linear polymer, and between about 15 and 60 by weight elastomer. The filler is closely associated with the semi-crystalline linear polymer. The elastic film demonstrates a load loss value at a 50 percent elongation of less than about 50 percent, and a breathability of greater than about 100 g/m.sup.2/24 hours.

A branched ester composition obtainable by the reaction of a carboxylic acid with a branched alcohol composition under esterification reaction conditions wherein the branched alcohol composition has from about 8 to about 36 carbon atoms and an average number of branches per molecule of from about 0.7 to about 3.0, said branching comprising methyl and ethyl branches. The present invention further relates to personal care compositions for topical application to the skin or hair comprising said branched ester composition. The branched ester composition of the invention provides improved formulation flexibility.

A mild cleansing composition is disclosed. The composition includes a from about 3.5 percent to about 8.5 percent of an anionic surfactant; from about 0.1 percent to about 3 percent of a hydrophobically modified, crosslinked, anionic acrylic copolymer; and c) from about 1 percent to about 25 percent of a nonionic surfactant, wherein the weight ratio of component a) to component b) is about 1:1 to about 25:1. The composition is useful as shampoos, washes, baths, gels, lotions, creams, and the like.

A mild cleansing composition is disclosed. The composition includes a from about 1 percent to about 8 percent of an anionic surfactant; and from about 0.1 percent to about 3 percent of a hydrophobically modified, crosslinked, anionic acrylic copolymer, wherein the weight ratio of component a) to component b) is about 1:1 to about 20:1 and wherein the composition is substantially free of non-ionic surfactants. The compositions are useful as shampoos, washes, baths, gels, lotions, creams, and the like.

A cleansing composition including a) from about 0.1 percent to about 12.5 percent of an anionic surfactant; and b) from about 0.1 percent to about 8 percent of a hydrophobically modified, crosslinked, anionic acrylic copolymer, wherein the weight ratio of component a) to component b) is about 1:1 to about 40:1, and the composition is substantially free of amphoteric surfactants. The composition is useful as shampoos, washes, baths, gels, lotions, creams, and the like.

A mild cleansing composition is disclosed. The composition includes a from about 4 percent to about 8.5 percent of an anionic surfactant; from about 1 percent to about 30 percent of an amphoteric surfactant; and from about 0.1 percent to less than about 3 percent of a hydrophobically modified, crosslinked, anionic acrylic copolymer, wherein the weight ratio of anionic surfactant to hydrophobically modified, crosslinked, anionic acrylic copolymer is about 3:1 to about 40:1. The composition is useful as shampoos, washes, baths, gels, lotions, creams, and the like.

The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides DNA molecules that encode novel variants, host cells comprising DNA encoding novel variants, as well as methods for making proteins less allergenic. In addition, the present invention provides various compositions that comprise these proteins that are less immunogenic than the wild-type proteins.

The present invention provides engineered enzymes generated from protein scaffolds combined with Specificity Determining Regions, the production thereof and the use of said engineered enzymes for research, nutritional care, personal care and industrial purposes.

Disclosed is a fluid personal care composition comprising a metal oxide silicate and a vehicle, wherein the metal oxide silicate is capable of absorbing a malodorous compound. These fluid personal care compositions that provide effective, long-lasting suppression of the malodors associated with human perspiration. The personal care composition may be in the form of a solid stick deodorants, liquid roll-on deodorants, aerosol, and pump spray deodorants, semi-solid gel deodorants, soap bars, and deodorant lotions and creams.

In an extraction process comprising extracting a raw extract from Emblica officinalis the improvement comprising conducting the extraction under conditions of time, temperature and atmosphere, to inhibit the formation of black specks and/or oligomeric and/or polymeric tannins and/or oxidation products thereof.

The invention described herein relates to compositions of novel antimicrobial peptides. The peptides of the present invention exhibit high antibacterial activity and low hemolytic activity. The invention further provides compositions comprising these antimicrobial peptides and methods of use thereof for killing, reducing the growth of, or preventing the growth of microorganisms. The invention also provides antimicrobial substrates and articles comprising the peptides of the present invention.

Provided are methods of reducing the irritation associated with a personal care composition comprising an anionic surfactant, the methods comprising combining a hydrophobically-modified material capable of binding a surfactant thereto with an anionic surfactant to produce a reduced irritation personal care composition, and methods of using such compositions to cleanse the hair or skin with reduced irritation.

Provided are methods of reducing the irritation associated with a personal care composition comprising an anionic surfactant, the methods comprising combining a hydrophobically-modified material capable of binding a surfactant thereto with an anionic surfactant to produce a reduced irritation personal care composition, and methods of using such compositions to cleanse the hair or skin with reduced irritation.

Provided are methods of reducing the irritation associated with a personal care composition comprising an anionic surfactant, the methods comprising combining a hydrophobically-modified material capable of binding a surfactant thereto with an anionic surfactant to produce a reduced irritation personal care composition, and methods of using such compositions to cleanse the hair or skin with reduced irritation.

The present invention relates to a composition and process for stabilizing the rheology of softeners including fragrances and softeners including added fragrances using cationic emulsion polymers.

Compounds of the general formula I' 1 in which R.sup.1 is H, C.sub.1-C.sub.12alkyl; C.sub.5-C.sub.12cycloalkyl; C.sub.2-C.sub.18alkyl which is interrupted by one or more O; SR.sub.4; OR.sub.5; or is a group of formula II or III 2 R.sub.2, R.sub.21 and R.sub.3 independently of one another, are H or --Y-T as defined in claim 1, where T is a reactive group selected from OH, acryl- and methacryloxy and arylcarbonate groups, and further symbols are as defined in claim 1, are effective as crosslinking agents for polymeric networks, especially as in flexographic printing plates, coatings, and plastic containers or films. Further provided is a method of protecting the content of a clear or lightly colored plastic container or film against the deleterious effects of ultraviolet radiation, which method comprises permanently and covalently bonding one or more UV absorbing moieties of a durable s-triazine UV absorber via condensation to a suitable polymer component.

Disclosed are cleansing compositions comprising one or more surfactants selected from the group consisting of: i) anionic surfactants, ii) amphoteric surfactants, iii) nonionic surfactants, iv) cationic surfactants and v) mixtures thereof, where the dynamic viscosity of the compositions at 25.degree. C. is at least about 100,000 centipoise and where the cleansing composition results in no or minimal eye sting. Also disclosed disposable articles comprising water insoluble substrates releasably containing the cleansing compositions, a process for making the disposable articles and a method of use.

Personal care compositions that provide improved cleansing and anti-dandruff efficacy. These compositions have from about 5 to about 50 weight percent of a detersive surfactant, from about 0.1 to about 4 weight percent of an anti-dandruff agent, from about 0.001 to about 50 weight percent of at least one ketoamide surfactant, and at least about 20 weight percent water.

A bonded structure including one or more substrates bonded together with a tackified amorphous poly-alpha-olefin adhesive composition. One method of making such a bonded structure is carried out by applying a tackified amorphous poly-alpha-olefin adhesive composition to one or more substrates at a temperature of about 170 degrees Celsius or lower, and joining the substrates to themselves or to one another. The bonded structure has a dynamic peel strength between about 400 and about 1000 grams per 25 millimeters. The bonding efficiency of the bonded structure renders the bonded structure suitable for incorporation into a variety of articles, including personal care products, health/medical products, and household/industrial product, for example.

High-viscosity elastomeric adhesive compositions including a high softening point tackifier resin in combination with a base polymer can be used to create elastomeric composite laminates having effective adhesion and elastic properties. The elastomeric adhesive compositions suitably have a viscosity between about 100,000 and about 500,000 cps at between about 300 degrees Fahrenheit (149 degrees Celsius) and about 350 degrees Fahrenheit (177 degrees Celsius). Facing layers, such as nonwoven webs, films, elastic strands, fastening material, absorbent material, and the like, can be laminated to one or both surfaces of the elastomeric compositions to form elastomeric composite laminates. A method of making such compositions and laminates involves forming the compositions into elastomeric adhesive films and/or strands.

Disclosed are personal cleansing compositions for rinse-off application to the hair, nails or skin. These compositions comprise a silicone-resin based adhesive including a silicone resin copolymer as a condensation product of an organosiloxane fluid and a silicone resin; a cleansing surfactant; and a carrier liquid. The personal cleansing compositions can also comprise as the silicone-resin based adhesive, in addition to or in place of the silicone resin copolymer, a combination of an organosiloxane resin and a diorganosiloxane fluid at a weight ratio of said resin to said fluid of from about 1:9 to about 10:1. The personal cleansing compositions provide hair styling benefits when applied to the hair, and when applied to the skin, barrier protection from surfactants or other materials having skin irritation potential.

The present invention relates to multi-phase personal care composition containing at least two visually distinct phases wherein at least one phase contains a particle. The phases form a pattern and are packaged in physical contact while remaining stable over time.

The present invention relates to the use of acrylate copolymers, which provide excellent water resistance to personal care products without the undesirable waxy, greasy or heavy feel. Further, these acrylate copolymers are easy for manufacturers to use as they can be easily incorporated into the water phase without special processing.

The invention provides a biodegradable polymer composition for a breathable film which comprises a biodegradable polyester such as polylactic acid, a biodegradable copolyester such as an aliphatic/aromatic copolyester, and a filler such as calcium carbonate. These compounds are melt blended and film formed and the film is then stretched in a monoaxial or biaxial direction to enhance pore formation and hence also enhance the breathability of the film. The water vapor transmission rate (WVTR) of the film is typically greater than 3,000 grams per square meter per day so that the film is suitable for use in disposable articles such as wipes, diapers, training pants, absorbent underpants, adult incontinence garments, feminine hygiene products, medical garments, bandages and the like.

The present invention relates to a personal care composition comprising at least one hydroxyalkylurea in combination with at least one other moisturizing agent in a synergistically moisturizing effective ratio, which provides not only the perception of moisturization, but also actual increased moisturization efficacy. Such personal care compositions provide an enhanced smooth feel as well as enhanced flexibility, elasticity, suppleness and firmness without leaving a heavy or greasy feel.

A personal care composition having at least one hydroxyalkylurea (HAU) optionally in combination with at least one other moisturizing agent. The at least one HAU, alone or together with the at least one moisturizing agent, provides not only the perception of moisturization, but also actual increased moisturization efficacy. When the two are used in combination in a personal care composition, they are provided in a synergistically moisturizing effective ratio to provide that perception of moisturization and increased moisturization efficacy. Such personal care compositions provide an enhanced smooth feel as well as enhanced flexibility, elasticity, suppleness and firmness without leaving a heavy or greasy feel.

A method for providing antimicrobial or antiviral preservation to a liquid-containing composition is disclosed. The method comprises dissolving or dispersing an antimicrobial or antiviral amount of a compound having a molecular weight of about 200 to about 800 Da that is (i) a hydrocarbyl aminohydrocarbonate, (ii) an aminohydrocarbyl hydrocarbonate, (iii) a mixture of (i) and (ii) in that liquid-containing composition. A method of sanitizing a surface is also contemplated that comprises applying a composition prepared by the above method to contact a surface to be sanitized and maintaining that contact for a time sufficient to sanitize the same.

The composition comprises (i) one or more ozonized oils and/or natural and/or synthetic ozonized products and (ii) thioctic acid and/or the derivatives thereof, wherein each of the components is present in a concentration ranging from 0.01% to 99.99% by weight in relation to total weight and optionally one or more active substances, additives, vehicles or excipients. Said composition can be used to prepare pharmaceutical, cosmetic, dietetic and food supplement compositions for humans and animals.

A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.

The invention relates to a process for preparing microcapsules by coacervation, wherein the cross-linking of a protein is carried out by a plant extract rich in substituted or unsubstituted phenolic compounds.

A composition suitable for use in personal cleaning or detergent soap bars, which includes a sulfonated fatty acid or alpha sulfonated alkyl ester, and methods for producing such a composition. The composition and methods exhibit efficient processing and allow for formation of cleansing or detergent bars with improved hardness, improved resistance to marring and improved processability to marring, lower wear-rate and decreased mush formation during consumer use.

Disclosed are improved cleaning compositions comprising soap&com ma; fatty acid, synthetic detersive surfactant, salt and a polyhydridic alcohol, which are suitable for formation into precursor cleansing/laundry bar "soap noodles," personal cleansing bars and laundry detergent bars. The compositions comprise: (a) from about 58% to about 93% by weight of an approximately 70% aqueous soap slurry; (b) from about 1% to about 15% by weight of a fatty acid; (c) from about 2% to about 30% by weight of an approximately 55% aqueous mixture of anionic surfactants comprising i) an alpha sulfonated alkyl ester, and ii) a sulfonated fatty acid or salts thereof, wherein the ratio of i) to ii) is from about 10:1 to about 1:10; (d) from about 0.5% to about 2% by weight of a salt; (e) from about 0.5% to about 5% by weight of a 25 polyhydridic alcohol; and (f) from 0 to about 10% by weight of an alkanolamide of the formula O CH.sub.3(CH2).sub.nCNH(CH.sub.2).sub.yOH wherein n=6-16, and y is 2-4; The invention additionally relates to an improved process for producing both precursor cleansing/laundry bar "soap noodles" and personal cleansing/laundry detergent bars 35 comprising combining (a)-(e) to form a liquid mixture at a temperature of about 65.degree. C. to about 105.degree. C., removing from about 50% to about 90% by weight of the water from the liquid mixture, by heating up to 150.degree. C. under vacuum conditions or 105.degree. C. at normal conditions to form a thickened mixture, extruding the thickened mixture to form flaked solid or semi-solid pellets or noodles, and optionally, plodding the flaked solid or semi-solid pellets or noodles to form plodded pellets or noodles,f extruding the plodded pellets or noodles to form a billet, cutting the billet, and stamping the cut billet to yield a personal cleansing/laundry detergent bar. 1

What is described herein are antimicrobial compositions which are defined blends of a 1,2-diol and phenoxyethanol which show broad activity against bacteria, fungi and mold spores. This activity is potentiated by the addition thereto of small amounts of a co-biocide for which the blend acts as a delivery system for the otherwise water-insoluble co-biocide.

The present invention relates to the use of a mixture of modified starch and protein for encapsulating oxygen sensitive agents, wherein the modified starch is a starch derivative containing a hydrophobic group or both a hydrophobic and a hydrophilic group which has been further enzymatically hydrolyzed by an exo-enzyme. The encapsulated materials have a high level of active agent and retention and provide excellent oxidation resistance. Further, the encapsulated materials are useful in a variety of products, including food products.

Use as a flavour ingredient of an aliphatic or aromatic unsaturated amide of formula (I). 1

An optically clear aqueous structured surfactant composition that includes from 0 parts by weight to less than 2.5 parts by weight sugar per 100 parts by weight of the composition, and from greater than 7.7 parts by weight to about 50 parts by weight of an anionic surfactant per 100 parts by weight of the composition, and wherein at least a portion of the anionic surfactant is in the form of spherulites, is useful as a ingredient in personal care compositions.

A personal care composition that comprises a sunless tanning active, a surface active, a lipid, and an aqueous phase; wherein the lipid, the sunless tanning active, and the surface active form a lipid phase; wherein the sunless tanning active and the surface active are on the surface of the lipid, within the domain of the lipid, or both on the surface and within the domain of the lipid in the lipid phase. These compositions deposit sunless tanning actives on keratinous surfaces as well as provide improved skin moisturization, appearance, aesthetics and skin feel during and/or after application. The present invention is further directed to a method of using the personal care composition.

A personal care composition comprising a hydrophilic liquid, a structurant for said hydrophilic liquid, a surface active, a lipid, and an aqueous phase; wherein said lipid, said hydrophilic liquid, said structurant, and said surface active form a lipid phase; wherein said hydrophilic liquid, said structurant, and said surface active are connected to said lipid in said lipid phase. These compositions provide improved skin and/or hair moisturization, appearance, aesthetics and skin and/or hair conditioning during and/or after application, and are useful in providing improved deposition to the desired area of the skin and/or hair. The present invention is further directed to a method of using the personal care composition.

The present invention provides methods for the identification of CD4.sup.+ T-cell epitopes in subtilisin Carlsberg proteins. The present invention also provides for the production of altered peptides which, when incorporated into a wild-type subtilisin Carlsberg protein produce an altered immunogenic response, preferably a low immunogenic response in humans. In particular, the present invention provides means, including methods and compositions suitable for reducing the immunogenicity of ALCALASE.RTM. enzyme.

A personal care composition comprising a hydrophilic benefit active, a multi-wetting material, and an aqueous phase, wherein the hydrophilic benefit active may be a hydrophilic solid or a hydrophilic liquid with a structurant, wherein the multi-wetting material and the hydrophilic benefit active form a multi-wetting phase. These compositions provide improved skin and/or hair moisturization, appearance, aesthetics and skin and/or hair conditioning during and/or after application, and are useful in providing improved deposition to the desired area of the skin and/or hair. The present invention is further directed to a method of using the personal care composition.

The present invention relates to a personal care composition containing water that has been treated with a combination of ozone and hydrogen peroxide. The personal care composition is further treated with liquid oxygen that is added to the composition prior to packaging. The personal care composition may be in the form of a soap, lotion, cream, balm, stick, foundation, spray, mousse, gel, sanitizer, wash, or towellete, and directed for various uses on the human body. The ozone and hydrogen peroxide is added to the water prior to manufacturing the composition.

The present invention provides nonwoven fabrics that include a first level and a second level wherein the first level includes first fibers that include a polyolefin and a first amount of an additive or a combination of additives to improve wettability and the second level includes second fibers that include a second amount of an additive or a combination of additives to improve wettability wherein the second amount of an additive or a combination of additives to improve wettability is essentially zero or is less than the first amount of an additive or a combination of additives to improve wettability. In one desirable embodiment, the wettability of the fabric is temperature dependent and may decrease as the temperature decreases. Such fabrics may be useful as components in absorbent products, for example liners and surge management layers, by providing components that are wettable during an initial insult and then decrease in wettabilty as the insult cools to discourage flow back of the insult.

An article of commerce is provided which includes (a) an inverted container that includes a valve and an aperture; (b) a personal care composition contained in the inverted container, and (c) a hanging feature. An article of commerce is provided that includes (a) an inverted container comprising a valve; (b) an in-shower moisturization composition contained in said inverted container; and (c) a set of instructions in association with the inverted container, the set of instructions comprising instructions to dispense the in-shower moisturization composition from the inverted container, contact skin with the in-shower moisturization composition during showering or bathing, rinse the skin, and dry the skin. A personal care kit is provided and methods for utilizing the personal care compositions are provided which enhance skin and/or hair moisturization and conditioning.

Personal care compositions comprising at least one chronic skin care active selected from the group consisting of butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), hexamidine, hexyl isobutyrate, menthyl anthranilate, methofuran, 3-butylidenepthalide, cetyl pyridinium chloride, green tea extract, catechins, phytosterols, ursolic acid, and plant extract compounds; at least one acute skin care active selected from the group consisting of particulate materials (including particles, pigments, and cross-linked silicone elastomers), panthenol, pantothenic acid derivatives, and tanning actives; and a dermatologically acceptable carrier. The composition can also comprise the cationic thickener, Polyquatemium 37. The present invention also relates to methods of using such compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.

Personal care compositions comprising at least one chronic skin care active selected from the group consisting of butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), hexyl isobutyrate, menthyl anthranilate, methofuran, 3-butylidenepthalide, cetyl pyridinium chloride, green tea extract, catechins, phytosterols, ursolic acid, and plant extract compounds; at least one acute skin care active selected from the group consisting of particulate materials (including particles, pigments, and cross-linked silicone elastomers), alkane polyols, panthenol and pantothenic acid derivatives, and tanning actives; and a dermatologically acceptable carrier. The composition can also comprise the cationic thickener, Polyquaternium 37. The present invention also relates to methods of using such compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.

The present invention relates to a hair fixative film, which contains a natural and/or synthetic polymer as the main component and a method of applying said film to hair. Such film is useful in maintaining a desired look and style of hair. Furthermore, the film is beneficial because it enables the combination of ingredients that are incompatible in other application forms.

The invention provides a personal care product that does not contain a lower viscosity silicone fluid; the personal care product includes at least one polyol polyester that is the esterification reaction product of a polyol having three to six carbons atoms and a carboxylic acid having three to six carbon atoms and a personal care formulation. Also provided are replacement compositions for use in personal care products that are at least one polyol polyester that is the esterification reaction product of a polyol having three to six carbons atoms and a carboxylic acid having three to six carbon atoms and having a kinematic viscosity of about 2 to about 20 centistokes at 25.degree. C. and wherein the replacement composition does not contain a low viscosity silicone fluid. Related methods are also described.

Novel, crosslinked polymers using biomass derived materials, such as aldaric acids and derivatives, are provided. The polymers can be used as hydrogels and in antimicrobial compositions.

Novel methods for measuring the soothing attributes of personal care compositions are disclosed. The methods disclosed are particularly suitable for measuring and comparing the soothing attributes of facial tissue to determine which facial tissue is most soothing to damaged skin. The methods include damaging the skin of a test subject to a predetermined amount, contacting a test tissue. In a preferred embodiment, the amount of skin damage on the skin is determined by the test subject.

The present invention relates to a copolymer derived from the polymerization of a) at least one cationic monomer of formula (I), where in R.sub.1 is hydrogen or methyl, R.sub.2 is hydrogen or C.sub.1-C.sub.4alkyl, R.sub.3, R.sub.4 and R.sub.5 are independently from each other hydrogen or C.sub.1-C.sub.4alkyl, n is a integer from 1-5, and Y is a counterion, and b) as least one monomer of formula (II) wherein R.sub.6 signifies hydrogen or methyl, and R.sub.7, R.sub.8 and R.sub.9 signify independently from each other hydrogen or C.sub.1-C.sub.4alkyl, with the proviso that at least one of the substituents R.sub.6, R.sub.7, R.sub.8 and R.sub.9 and C.sub.1-4alkyl and c) optionally at least one cross-linking agent, which contains at least two ethylenically unsaturated moieties, as well as to their use in personal care product and to the personal care products. 1

The present invention provides a cosmetic product comprising cosmetically acceptable ingredients in a liquid carrier, and a thickener of the formula 1 wherein R.sub.1 is a saturated or unsaturated C.sub.8-C.sub.40 group; R.sub.2 is a saturated or unsaturated C.sub.8-C.sub.24 group, n=1-200, m=0-200, and p=0-200.

A disposable substrate comprising a foam particles or a foam layer with a nonwoven layer or an additional foam layer can be used to effectively clean surfaces. The disposable substrate can be a wipe or a cleaning pad. The cleaning pad can be attached to a cleaning implement. The disposable substrate can contain a cleaning composition. The disposable substrate can be used for personal care cleansing and absorption applications. One example of a suitable foam, for incorporation in the substrate, is melamine foam.

Isolated and purified nucleic acids encoding green fluorescent proteins from Renilla reniformis and the green fluorescent protein encoded thereby are also provided. Mutants of the nucleic acid molecules and the modified encoded proteins are also provided. Compositions and combinations comprising the green fluorescent proteins and/or the luciferase are further provided.

Triazine derivatives of formula (1) wherein R.sub.1 is C.sub.1-C.sub.20alkyl; C.sub.3-C.sub.7cycloalkyl; or C.sub.1-C.sub.20perfl C.sub.1-C.sub.20alkyl; or C.sub.3-C.sub.7cycloalkyl- ; and R.sub.3 is hydrogen; C.sub.1-C.sub.20alkyl; C.sub.3-C.sub.7cycloalky- l; C.sub.1-C.sub.20perfluoroalky; C.sub.1-C.sub.20alkyl-carbonyl; C.sub.3-C.sub.7cycloalkyl-carbonyl; C.sub.1-C.sub.20perfluoroalkyl-carbon- yl; or phenylcarbonyl; are described. The compounds exhibit pronounced action against gram-positive and gram-negative bacteria and also against yeasts and moulds. They are also suitable for treating or preventing biofilms on human tooth surfaces and oral mucosa. 1

Isolated and purified nucleic acids encoding green fluorescent proteins from Renilla reniformis and the green fluorescent protein encoded thereby are also provided. Mutants of the nucleic acid molecules and the modified encoded proteins are also provided. Compositions and combinations comprising the green fluorescent proteins and/or the luciferase are further provided.

A package for a personal care composition comprising: (a) a bottle; (b) a cap, wherein the cap is attached to the bottle; and (c) a shrink label, wherein the shrink label covers at least a portion of the bottle and a portion of the cap, and wherein the shrink label covers a gap between the bottle and the cap. The package can prevent water from accumulating between the cap and bottle when the package is used in a wet environment, such as the shower or bath, which can lead to the formation of mold and/or mildew between the cap and bottle. The package also can dissuade consumers in a retail store from unscrewing or otherwise removing the cap from the bottle, which can lead to leakage of the personal care composition onto the store shelves.

The present invention is a multi-phased personal care composition that contains at least two visually distinct phases. At least one visually distinct phase contains a cleansing phase and at least one visually distinct phase contains a colorant. The colorant is substantially free of Barium and/or Aluminum. The phases are packaged in physical contact with one another

This invention relates to the use of a vinic alcohol in cosmetic compositions, perfumes and personal care products. The vinic alcohol is characterized as being a product from the grape fermentation followed by a purification by distillation and is used in this invention in total or partial substitution of the conventional ethylic alcohol. The vinic alcohol contains residual substances, which are a characteristic feature of the fermentation of grapes, affording a characteristic odor to the ethanol, contributing to a different olfactory sensorial perception.

A personal cleansing kit and related method are described. The kit includes a water-insoluble fibrous web folded into a plurality of pleats, each adjacent pleat adhering to one another from about 3 to about 100 separate personal washing events and a cleansing composition having from about 0.5 to about 60% by weight of surfactants in a carrier.

A personal care composition comprising a hydrophilic solid, a surface active, a lipid, and an aqueous phase; wherein the lipid, hydrophilic solid, and surface active form a lipid phase; wherein the hydrophilic solid and the surface active are on the surface of the lipid, within the domain of the lipid, or both on the surface and within the domain of the lipid in the lipid phase. These compositions provide improved skin moisturization, appearance, aesthetics and skin conditioning during and/or after application, and are useful in providing improved deposition to the desired area of the skin. The present invention is further directed to a method of using the personal care composition.

Disclosed is a personal care composition comprising by weight: (a) from about 0.01% to about 10% of a sparingly soluble solid oily component; (b) from about 0.05% to about 50% of a solvent for the sparingly soluble solid oily component; (c) from about 0.01% to about 10% of an emulsifier; and (d) water; wherein the composition is an emulsion. The composition of the present invention provides reduced or eliminated crystals and precipitations of sparing soluble solid oily components.

The use of various novel oxime ethers are described as fragrance chemicals. These chemicals are suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products is disclosed.

Alkylsulfonated polyaminosaccharides, such as alkylsulfonated chitosan, having a sultone substituent covalently bonded to the amino group and a known size and degree of substitution may be produced by methods of the invention. Such methods may include heating of the polyaminosaccharide in a polar solvent, such as alcohol, ether, or alcoholether to reflux, then adding an alkyl sultone. Alkylsulfonated polyaminosaccharides of the present invention may be used in a wide variety of applications. Alkylsulfonated chitosan is particularly useful in wound healing.

Phenylethyl benzoate for use in antiperspirant compositions, as well as an emollient additive, is disclosed. Personal care compositions such as antiperspirants, shampoos and hair conditioners comprising phenylethyl benzoate in the amount of from about 0.5% to about 50% by weight of the composition are disclosed.

A personal care cleansing article is provided which includes a cleansing composition having a lathering surfactant and a water absorbing material capable of accepting at least ten times the weight of the material of water, the composition being held within a water-insoluble sachet.

3-(methoxymethyl)-2-pentylcyclopent derivative compounds having the structure set forth below are disclosed: 1 where: the dotted line represents a potential double bond; R is selected from methyl and ethyl; and X is a C.sub.1-C.sub.7 hydrocarbon moiety. These compounds are useful fragrance chemicals, suitable for use in creating fragrances and scents in items such as perfumes, colognes and personal care products.

Polyol polyester polymers are provided which are useful for personal care formulations and products containing such formulations. The polyol polyester polymers include a reaction product of at least one polyfunctional alcohol, at least one polyfunctional carboxylic acid and at least one monofunctional carboxylic acid, wherein the polyfunctional alcohol includes about two to about ten carbon atoms, the polyfunctional carboxylic acid includes one to about thirty-six carbon atoms and the monofunctional carboxylic acid includes about four to about twenty-four carbon atoms. Such polyol polyester polymers can have a dynamic viscosity at 25.degree. C. of about 200 to about 5000 centipoise and a hydroxyl value of about 40 to about 300 KOH/g.

The present invention provides personal care compositions comprising a carrier and a mixture of essential oil components having specific levels of eucalyptol, terpene materials and auxiliary fragrance materials. The compositions herein gentle to skin and have a fragrance and activity similar if the composition were made using the pure extracted essential oil.

Personal care compositions comprise (a) from about 0.01 wt. % to about 10 wt. % of a water-soluble cationically modified starch polymer, wherein said water-soluble cationically modified starch polymer has a molecular weight from about 1,000 to about 200,000 and a charge density from about 0.7 meq/g to about 7 meq/g; (b) from about 5 wt. % to about 50 wt. % of an anionic surfactant system, said anionic surfactant system comprising at least one anionic surfactant and having an ethoxylate level and an anion level, (i) wherein said ethoxylate level is from about 1 to about 6, and (ii) wherein said anion level is from about 1 to about 6; and (c) a cosmetically acceptable medium. Personal care compositions as described above further comprise from about 0.01 wt. % to about 10 wt. % of one or more oily conditioning agents. Methods of treating hair or skin comprise applying the personal care compositions as described above to the hair or skin and rinsing the hair or skin.

The present invention provides cosmetic compositions that form a durable film or coating on surfaces such as hair or skin. The compositions of the invention comprise one or more anionic silicones and one or more high molecular weight esters, the combination of which provides a durable film. Methods for treatment of hair and skin employing the compositions of the invention are also provided.

The present invention is a multi-phased personal care composition that contains at least two visually distinct phases. At least one of the visually distinct phases is a benefit phase that has a Flow Onset Temperature of at least about 97.degree. F.; and wherein said visually distinct phases form a pattern; and wherein said visually distinct phases are packaged in physical contact with one another and are stable.

The present invention relates to a personal care composition containing water that has been treated with a combination of ozone and hydrogen peroxide. The personal care composition is further treated with liquid oxygen that is added to the composition prior to packaging. The personal care composition may be in the form of a soap, lotion, cream, balm, stick, foundation, spray, mousse, gel, sanitizer, wash, or towellete, and directed for various uses on the human body. The ozone and hydrogen peroxide is added to the water prior to manufacturing the composition.

A disposable personal care cleansing article is provided having a cleansing composition adjacent to a water insoluble substrate formed of a fibrous web. A plurality of slits having a length ranging from about 6 to 40 mm are cut into the web. The slits allow the article to expand when a consumer applies the article to cleanse the body under a flow of water.

The present invention relates to crystalline and crystal-like forms of lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention relates to methods of purifying lipopeptides, including daptomycin, a lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, including strains that are resistant to conventional antibiotics. The present invention also relates to pharmaceutical compositions comprising the purified form of the lipopeptide and methods of using these compositions.

The invention relates to the synthesis of siloxane polymers containing self-complementary quadruple hydrogen bonding groups (4H-units). The resulting polymers show unique new characteristics that result from the reversible, physical interactions between the polysiloxane chains that are based on the (supramolecular) interactions between the 4H-units. The polysiloxanes in this invention show unprecedented bulk material properties and are used as gelling agents for silicone fluids. The resulting gels are clear and display good material properties, while having unparalleled high silicone fluid contents.

An aqueous based functional system contains a stable fluid polymer suspension (FPS) thickening agent of a polysaccharide, polyethylene glycol (PEG), and hydrated thickening silica. The functional systems may be formulations of personal care excluding oral care, household care, oil field servicing fluids, Civil Engineering servicing fluids, paper coatings, construction fluids, ceramic glazes, foods, firefighting retardants, mineral processing, aqueous based coatings, building materials, construction, pharmaceuticals, medical care, paper making process, and paper coating. The FPS provides to the functional system comparable or better rheology and viscosity properties as compared to when using similar thickening agents in dry, solid form. A method of preparing the aqueous based functional system is also provided by adding a sufficient amount of a stable FPS that is compatible with the functional system to the system to thicken the functional system.

An improved fragrance delivery system capable of providing controlled release of fragrance molecules in various consumer products is composed of a polymer having covalently bound fragrance moieties that are releasable in the form of fragrance molecules. Certain embodiments comprise globular polymer particles in which unbound fragrance molecules are occluded, absorbed and/or adsorbed. Certain other embodiments incorporate fragrance monomer units, which achieve reduced residuals upon complete release of the fragrance.

The present invention relates to an absorbent personal care and/or cleansing product for cosmetic and/or dermatological applications comprising at least one non-woven absorbent sheet comprising 10 to 100 wt. % lyocell fibers and 0 to 90 wt. % of at least one other natural, man-made natural and/or synthetic fiber, wherein the lyocell fiber has a fiber titer in the range from 0.5 to 3.5 dtex, wherein the absorbent sheet has a basis weight in the range from 20 to 500 g/m.sup.2, and a tensile strength in the range from 5 to 1000 N/5 cm in machine direction and in cross direction. Further, the present invention relates to the use of said absorbent product as puffs, pads, wipes, tissues, towels, toweletts, sponges, brushes, cotton balls, gloves, mitts, cotton tip swabs or as a part thereof in cosmetic and/or dermatological applications, in particular as a basis onto which a cosmetic composition and/or dermatological cleansing and/or skin care composition, in particular in the form of a lotion, is being placed and/or into which said composition is being impregnated.

Microparticles containing an effective amount of at least one fluorescent whitening agent, wherein said fluorescent whitening agent is entrapped in a transparent or translucent matrix polymer that has been formed from a blend of monomers comprising a first monomer which is an ethylenically unsaturated ionic monomer and a second monomer which is an ethylenically unsaturated hydrophobic monomer which is capable of forming a homopolymer of glass transition temperature in excess of 50.degree. C., wherein secondary particles are distributed throughout the matrix, which secondary particles comprise a hydrophobic polymer that has been formed from an ethylenically unsaturated hydrophobic monomer which is capable of forming a homopolymer having a glass transition temperature in excess of 50.degree. C. and optionally other monomers, which hydrophobic polymer is different from that of the matrix polymer, exhibit improved shatter resistance. They are useful in a personal care or cosmetic compositions, for example in masking or reducing the appearance of skin imperfections.

This invention discloses chemically modified polyaminosaccharides, in particular chemically modified chitosans, in the molecular structure of which a predetermined proportion of the amino functional groups is sulfonated by the hydrocarbyl sultone compound via a covalent bond. Such chemically modified polyaminosaccharides may be produced by a process of sulfonating an un-modified polyaminosaccharide having amino functional groups by a hydrocarbyl sultone compound in the presence of an organic solvent under a suitable temperature. Chemically modified chitosans of this invention may be used in a variety of applications, including wound healing.

The compositions of the present invention relate to personal cleansing compositions that provide increased hair volume and superior styling benefits. These compositions comprise a surfactant system, a per-alk(en)yl hydrocarbon material having a molecular weight less than about 4200 and a particle size of from about 0.01.mu. and 40.mu., a cationic polymer and an aqueous carrier.

Compositions comprising polytetramethylene glycol and a volatile material (e.g. a perfume) are able to sustainedly release said volatile material and are easy to disperse in liquid and cream products.

Personal cleansing compositions comprise (a) from about 5 wt. % to about 50 wt. % of a water-soluble detersive surfactant; (b) at least about 0.1 wt. % of a fiber having a length and a thickness such that said length is greater than said thickness, wherein said length is from about 5 .mu.m to about 1.5 mm; and (c) at least about 20 wt. % of an aqueous carrier; wherein said fiber forms a load-sensitive deposit upon dilution of said personal cleansing composition with water. Methods of providing both increased volume and superior styling and conditioning to hair comprise applying the personal care composition as described above to the hair and rinsing the hair.

Personal cleansing compositions comprise (a) from about 5 wt. % to about 50 wt. % of a detersive surfactant, (b) from about 0.05 wt. % to about 20 wt. % of a first particle which is a wax particle having a melting point of at least about 90.degree. C. and an average mean particle size as measured in said personal cleansing composition from about 0.15 .mu.m to about 100 .mu.m; (c) from about 0.05 wt. % to about 20 wt. % of a second particle which is selected from platelet particles, irregularly shaped particles, and mixtures thereof, the second particle having an average particle size as measured in said personal cleansing composition from about 0.15 .mu.m to about 300 .mu.m; and (d) at least about 20 wt. % of a cosmetically acceptable medium; wherein the first particle and the second particle together form a load-sensitive deposit upon dilution of said personal cleansing composition with water. Methods of providing both increased volume and superior styling and conditioning to hair comprise applying the personal care composition as described above to the hair and rinsing the hair.

A packaged mousse-forming, personal care composition, comprising an aluminium based container with an inner surface coating of a thermosetting resin, wherein the composition comprises an aqueous base and a propellant, wherein the aqueous base comprises 0.16% or less by weight of chloride ions and has a pH of from 5.0 to 8.0.

Water-in-oil emulsions, compositions, and methods that include a vinyl polymer that includes ethylene oxide-containing side chains and alkyl-Y-containing side chains, wherein Y is O or NR, wherein R is H or CH.sub.3, and wherein the alkyl group of the alkyl-Y-containing side chain has at least 4 carbon atoms on average in a cyclic, branched-, or straight-chain configuration and optionally including one or more heteroatoms.

Compositions comprising one or more polymeric suds volume and suds duration enhances which are mild on the user's skin. The polymeric suds enhances are suitable for use in methods which in use as compositions light duty liquid, LDL compositions, hand dishwashing compositions, laundry bars, personal cleansing compositions and the like.

The invention relates to preparations for impregnating cosmetic wipes, characterized in that they contain (a) an emulsifier mixture containing nonionic and amphoteric surfactants in a quantity ratio of 10:1 to 1:1, based on the quantity of emulsifiers, (b) a mixture of wax components containing wax esters, partial glycerides and fatty alcohol ethoxylates and (c) at least one cationic polymer. The preparations containing wax particles lead to optimal foaming and cleansing performance and to a favorable sensorial impression.

An aqueous, low pH structured surfactant composition, contains, based on 100 parts by weight of the composition, from about 3 parts by weight to about 40 parts by weight of one or more anionic surfactants selected from anionic phosphate ester surfactants, anionic sulfonate surfactants, and anionic carboxylate surfactants, wherein the composition exhibits a pH of less than about 5, exhibits shear-thinning viscosity, and is capable of suspending water insoluble or partially water soluble components.

The use of novel methanoazulenofuran and methanoazulenone compounds for use as fragrance chemicals, suitable for use incorporated in a wide variety of products such as perfumes, colognes and personal care products having a structure

A reduced odor composition is composed of a functional system such as household care, personal care or pet care products and at least one cationic polygalactomannan or a derivative of cationic polygalactomannan having a cationic degree of substitution (DS) lower limit of about 0.01 and an upper limit of about 3.0 and weight average molecular weight (Mw) having a lower limit of 200,000 and an upper limit of 2,000,000 a concentration with a lower limit of 0.005 wt % and an upper limit of 10 wt %, and a trimethylamine content of less than 25 ppm, wherein the composition, at an alkaline pH, has no discernible amine odor.

Compounds of Formula (1), wherein R.sub.1 is hydrogen; C.sub.1-C.sub.18alkyl; trifluoromethyl; C.sub.3-C.sub.8cycloalkyl; phenylC.sub.1-C.sub.5alkyl; phenyl-C.sub.1-C.sub.5alkoxy; mono- or di-N-C.sub.1-C.sub.5alkamino-C.sub.1-C.sub.5alkyl; amino-di-N-C.sub.1-C.sub.5alkylamino-C.sub.1-C.sub.5alkyl; C.sub.1-C.sub.5alkoxy-C.sub.1-C.sub.5alkyl; R.sub.2 is C.sub.2-C.sub.20alkyl; hydroxy-C.sub.1-C.sub.20alkyl; phenyl; phenyl-C.sub.1-C.sub.5alkyl; phenyl-C.sub.1-C.sub.5alkoxy; mono- or di-N-C.sub.1-C.sub.5alkylamino-C.sub.1-C.sub.5alkyl; amino-di-N-C.sub.1-C.sub.5alkylamino-C.sub.1-C.sub.5alkyl; or heteroaryl-C.sub.1-C.sub.5alkyl; or R.sub.1 and R.sub.2 together with the nitrogen atom bonding them form a 5- to 7-membered monocyclic heterocyclic ring; are described. They are suitable for the antimicrobial treatment of surfaces, especially as antimicrobial active ingredients against gram-positive and gram-negative bacteria.

Inhibitors of axillary malodour having the formula wherein R has the same meaning as given in the specification.

Disclosed are cleansing compositions comprising one or more surfactants selected from the group consisting of: i) anionic surfactants, ii) amphoteric surfactants, iii) nonionic surfactants, iv) cationic surfactants and v) mixtures thereof, where the dynamic viscosity of the compositions at 25.degree. C. is at least about 100,000 centipoise and where the cleansing composition results in no or minimal eye sting. Also disclosed disposable articles comprising water insoluble substrates releasably containing the cleansing compositions, a process for making the disposable articles and a method of use.

A branched sulfopolyester mixture useful in adhesive and personal care product formulations. The branched sulfopolyester mixture includes: I) from about 65 to about 95 weight % of a branched water-dispersible polyester; and II) from about 5 to about 35 weight % of an alcohol. The branched sulfopolyester mixture is pourable at room temperatures.

A method and composition for imparting high shine to a polymeric substrate such as hair or skin, leather or a plastic which comprises applying thereto a phenylethyl or benzyl ester.

The present invention includes 1) a novel formulation for the treatment of hair loss comprising oleanolic acid (a 5.alpha.-reductase inhibitor), apigenin (a vasodilator), and biotinyl-GHK (a cell metabolism stimulant), 2) a novel additive for the treatment of hair loss comprising oleanolic acid, apigenin, biotinyl-GHK and a delivery agent, 3) a personal care, cosmetic, and/or dermopharmaceutical composition comprising oleanolic acid, apigenin, biotinyl-GHK, and at least one additional ingredient, and 4) a method for treating hair loss comprising the administration of oleanolic acid, apigenin, and biotinyl-GHK.

A multi-phase personal care composition is described that comprises a first visually distinct structured phase and a second visually distinct structured phase. The first visually distinct structured phase comprises a cleansing phase that includes about 2% to about 23.5%, by weight of the cleansing phase, of surfactant component. Preferably, the surfactant component comprises at least one branched anionic surfactant.

A stable multi-phase personal care composition is described. The stable multi-phase composition comprises least two visually distinct phases; wherein at least one visually distinct phase comprises a cleansing phase comprising a surfactant component. The surfactant component comprises at least one anionic surfactant selected from the group consisting of ammonium lauryl sulfate, ammonium laureth sulfate, sodium lauryl sulfate, sodium laureth sulfate, sodium cocoyl sulfate, sodium laurate, sodium cocoyl isethionate, monomethyl branched surfactants and mixtures thereof. The visually distinct phases of the stable multi-phase personal care composition form a pattern.

A stable, rinsable multi-phase personal care composition is described comprising at least two visually distinct phases. At least one visually distinct phase comprises from about 1% to about 99% of a depositable solid by weight of the composition; and wherein said stable multi-phase personal care composition provides at least about 0.2% Depositable Solids.

A multi-phase personal cleansing composition is described that comprises a cleansing phase comprising from about 2% to about 23%, by weight of the composition, of a surfactant component comprising a surfactant or a mixture of surfactants; and wherein the composition has a Structured Domain Volume Ratio of at least about 45%. Preferably, the surfactant component comprises at least one branched anionic surfactant. Preferably, the anionic surfactant comprises greater than 5%, by weight of the anionic surfactant, of a monomethyl branched anionic surfactant.

The present invention is a stable multi-phase personal care composition comprising: at least two visually distinct phases; wherein at least one visually distinct phase comprises a cleansing phase comprising from about 2% to about 90%, by weight of the cleansing phase, of a surfactant component; and wherein said cleansing phase comprises a polymeric phase structurant; and wherein said visually distinct phases form a pattern.

A copolymer of a vinyl lactam and vinyl carbazole useful in personal care compositions.

Personal care compositions comprise visible beads, cationic polymer, and surfactant. The visible beads in the personal care compositions can be utilized to provide an aesthetically pleasing appearance to the product. The visible beads can also be utilized to encapsulate and deliver skin benefit agents to the skin or hair. The visible beads can also encapsulate materials that are otherwise incompatible with the personal care composition matrix to preserve product stability.

A rheology modifier/hair styling resin which is a crosslinked, linear poly(vinyl amide/polymerizable carboxylic acid) copolymer exhibits advantageous hair care properties of high viscosity and long-lasting curl retention.

A personal care product is provided which includes a composition containing dihydroxypropyltri(C.sub.1-C.sub.3 alkyl) ammonium salt in a carrier. The composition is packaged for delivery to a consumer and includes instructions printed on or associated with the packaging indicating topical use of the composition on skin, hair or the oral mucosae. Particularly useful is dihydroxypropyltrimonium chloride which operates as a humectant to moisturize both at high and low relative humidity environments.

A personal care composition is provided which includes a quaternary ammonium compound which is a salt of hydroxypropyl tri(C.sub.1-C.sub.3 alkyl) ammonium mono-substituted mono-saccharide. Particularly preferred are hydroxypropyl trimonium quaternized glucose or fructose. These quaternary ammonium salts provide moisturization properties to the personal care composition both in high and low relative humidity environments.

A personal care product is provided which includes a package filed with a personal care composition and instructions printed on or associated with the package indicating topical use of the composition on skin for purposes of controlling the signs of aging. The composition includes a quaternary ammonium compound selected from (a) salts of hydroxypropyltri(C.sub.1-C.sub.3 alkyl)ammonium mono-substituted mono-saccharide; (b) salts of hydroxypropyltri(C.sub.1-C.sub.3 alkyl)ammonium mono-substituted polyols, the salts having a cation of an average molecular weight no higher than about 450 and the salt having a T.sub.g no higher than about 10.degree. C.; (c) dihydroxypropyltri(C.sub.1-C.sub.3 alkyl)ammonium salts; (d) chlorohydroxypropyltri(C.sub.1-C.sub.3 alkyl)ammonium salts; and (e) mixtures thereof.

A personal care product is provided which includes a composition a quaternary ammonium salt wherein a cation of the salt is a dihydroxypropyltri(C.sub.1-C.sub.3 alkyl)ammonium monosubstituted polyol in a carrier. The cation should have a molecular weight no higher than about 450 and the salt have a T.sub.g no higher than about 10.degree. C. Particularly preferred are hydroxypropyltrimonium sorbitol salts. These salts operate as humectants to moisturize both in high and low relative humidity environments.

The present invention relates to multi-phase personal cleansing compositions containing a lathering cleansing phase and a separate non-lathering structured aqueous phase wherein the two phases are packaged in physical contact while remaining stable over time.

Personal care compositions comprise (a) from about from about 5 wt. % to about 35 wt. % of a detersive surfactant; (b) at least about 0.05 wt. % of a galactomannan polymer derivative having a mannose to galactose ratio of greater than 2:1 on a monomer to monomer basis, the galactomannan polymer derivative selected from a cationic galactomannan polymer derivative and an amphoteric galactomannan polymer derivative having a net positive charge, the galactomannan polymer derivative having a molecular weight from about 1,000 to about 10,000,000 and a cationic charge density from about 0.9 meq/g to about 7 meq/g; and (c) at least about 20 wt. % of an aqueous carrier. Methods of treating hair or skin comprise applying the personal care composition as described above to the hair or skin and rinsing the hair or skin.

Described is a multiple (2-4)-compartment fluidic individually stable pre-storable composition storage and unstable mixture-forming and delivery container having separate compartments each communicating with a single mixing zone via an externally-located fluidic composition multiple delivery tube system juxtaposed with the outer surfaces of the compartment walls. These containers are well suited for storing and transporting compositions such as a cleaning agent composition, a personal care composition, an aqueous liquid detergent composition and/or a fabric softening composition and then promptly delivering the resulting unstable mixture to the desired location. The container has been advantageously found to deliver unstable mixtures which could include aqueous suspensions of microencapsulated fragrances or other ingredients.

The present invention relates to crosslinked protein crystals characterized by the ability to change from insoluble and stable form to soluble and active form upon a change in the environment of said crystals, said change being selected from the group consisting of change in temperature, change in pH, change in chemical composition, change from concentrate to dilute form, change in shear force acting upon the crystals and combinations thereof. According to one embodiment of this invention, such crosslinked protein crystals are capable of releasing their protein activity at a controlled rate. This invention also provides methods for producing such crosslinked protein crystals, methods using them for protein delivery and methods using them in cleaning agents, including detergents, pharmaceutical compositions, vaccines, personal care compositions, including cosmetics, veterinary compositions, foods, feeds, diagnostics and formulations for decontamination.

The present invention relates to an ozone-stressed yeast lysate, and a personal care composition including an ozone-stressed yeast lysate and at least one preservative selected from the group consisting of alcohols, glycols, parabens, hydantoins, quaternary nitrogen-containing compounds, isothiazolinones, aldehyde-releasing agents, and halogenated compounds. The present invention also relates to a method for preparing and using the ozone-stressed yeast lysate and the personal care composition.

Derivatized polysaccharide polymers that contain a fructan polymer substrate bearing one or more cationic substituent groups are useful in home and fabric care applications, in oilfield applications, and in emulsion polymerization applications.

A clear personal care or other aqueous gel is formed from dry polymer particles which are free of materials which render the gel cloudy and which are made by reverse phase emulsion polymerisation. The polymerisation process involves distilling water from the emulsion in the presence of sufficient non-aqueous liquid to prevent breakage of the emulsion and then washing, the polymer particles with isopropanol or other suitable solvent and evaporating the solvent.

The present invention relates to modulation of MAP2K2 and DUSP-1 genes and proteins encoded thereby. More specifically, the present invention relates to modulation of MAP2K2 and DUSP-1 genes to detect and condition photo-damaged skin, preferably, chronically photo-damaged skin, as well as to identify active compounds and compositions for skin conditioning.

The use of novel nonionic polymeric thickeners that produce cosmetically useful emulsions of an oil phase and a water phase is described. The thickeners of choice are the urethane dimers of ethoxylated fatty alcohols. These materials were not anticipated to have emulsifying properties. Also, it has been found that the esters of ethoxylated polyols show similar emulsifying behavior, although their uses are limited by their inherent susceptibility towards hydrolysis. Further, many of the emulsions produced with these emulsifiers have a dilatant or shear thickening rheology that is unusual and has unique cosmetic applications. In addition, it is possible to produce high internal phase oil-in-water emulsions, with oil phase concentrations greater than 70%, using these emulsifiers. Finally, many of the emulsions, especially the high internal phase ones, have a characteristic "ring" or vibration that is apparent when their container is tapped. This is a characteristic of so called "microemulsions" that has not been observed in conventional appearing, white (albeit dilatant) emulsions.

The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.

The invention relates to a single use cleansing sheet comprising: (a) a first fibrous water soluble polymer; (b) a second fibrous water soluble polymer which is different from said first fibrous water soluble polymer; wherein the ratio of (a) and (b) is effective to provide a cleansing sheet which wets out almost immediately upon contact with water; (c) a plasticizer in an amount effective to increase the flexibility and strength of the sheet; (d) a surfactant portion present in an amount effective to provide cleansing and lathering properties; and (e) water. In another embodiment, the invention relates to a method for cleansing the hands, face, hair, or body comprising wetting the cleansing sheet according to the invention with water, applying mild friction and contacting hands, face or body with the wetted sheet. In yet another embodiment, the invention relates to a single use personal care sheet comprising: (a) a first fibrous water soluble polymer; (b) a second fibrous water soluble polymer which is different from said first fibrous water soluble polymer (a); wherein the ratio of (a) and (b) is effective to provide a personal care sheet which wets out almost immediately upon contact with water; (c) a plasticizer in an amount effective to increase the flexibility and strength of the sheet; (d) a combination of at least one hydrophobic and at least on hydrophilic emulsifier in an amount effective to form a stable emulsion; and (e) water. In another embodiment, the invention relates to a method for treating,. i.e., moisturizing, protecting, soothing, etc., the hands, face, hair, or body comprising wetting the personal care sheet according to the invention with water, applying mild friction and contacting hands, face or body with the wetted sheet.

Mixture of dialkyl imidazoline quats with specified substitution content are provided. In one embodiment, at least a portion of the mixture includes at least one dialkyl imidazoline quat having at least one C.sub.16-C.sub.30 alkyl group; the C.sub.16-30 substitution content of the mixture being from about 10% to about 95% with respect to C.sub.10+ reference substitution range. Methods of making imidazoline quats and quat mixtures, personal care and cosmetic products and formulations that contain the imidazoline quats and quat mixtures, methods of making such personal care and cosmetic products and formulations, and methods of using the such imidazoline quats, quat mixtures, and personal care and cosmetic products and formulations are also provided. Various embodiments are disclosed.

A polypropylene composition comprises an isotactic polypropylene homopolymer resin that is suitable to form an injected molded article exhibiting less than about 60% haze, as determined by ASTM D1003, at a thickness of 0.05 inch without clarity-enhancing agents. The polypropylene composition has particular application to injection molded articles and may have a melt flow rate of from about 0.1 g/10 min to about 150 g/10 min as determined by ASTM D-1238, Procedure B. The resin may be prepared using a metallocene catalyst, and the composition may include clarity-enhancing agents for even greater clarity improvements.

A composition and a process for blocking water in an article are disclosed. The composition can comprise or be produced from a first polymer, a second polymer, and optionally a third polymer; the first polymer comprises an ethylene copolymer comprising repeat units derived from ethylene and a polar monomer; the second polymer comprises a polyacrylic acid or its salt or its cross-linked polymer thereof, a polymethacrylic acid or its salt or cross-linked polymer thereof, or combinations of two or more thereof; and the third polymer comprises polyvinyl alcohol. The process can comprise contacting the article with the composition.

A test method is described for comparing the relative affinity of products for a target substance using a substrate ordinarily and visibly sensitive to the products. The test method is useful in one embodiment for comparing the ability of harsh cleansers to remove fatty acids from the skin with mild cleansers that do not remove fatty acids to the same extent using a visually compelling substrate such as a fresh cut flower.

A personal care composition that includes a personal care ingredient and semiconductor nanocrystals. A method of protecting at least a portion of a body against ultraviolet radiation by applying a personal care composition is also provided.

Personal care compositions having plant fiber such as tapioca fiber, and methods of applying those formulations. The addition of fiber to personal care formulations can provide performance improvement such as cleansing, exfoliation, irritation reduction, suspending, foam enhancement, and rheological property modification.

A conditioning composition is used in functional systems (personal care and household care compositions) that has a nonionic hydrophobically modified cellulose ether (HMCE) having a weight average molecular weight (Mw) with a lower limit of 400,000 and an upper limit of 2,000,000 and a hydrophobic substitution lower limit of 0.6 wt % and an upper limit amount which renders said cellulose ether insoluble in a 5 wt % solution of surfactant and less than 0.05% by weight soluble in water and wherein the cellulose ether provides conditioning benefit to the functional system substrate. This composition has at least one active functional system ingredient.

Provided are compositions comprising a polymeric emulsifier, a hydrophobic agent, a wetting agent having at least one sulfonate group and at least one base-neutralizable carboxylic acid group, and a hydrophilic particulate material. Also provided are methods of mitigating diaper dermatitis using the composition, and methods of promoting the benefits associated with the compositions.

Provided are compositions comprising at least one polymeric emulsifier, at least one hydrophobic agent, and at least one foaming agent, the compositions exhibiting at least one of the properties selected from the group consisting of a Deposition Value of greater than about 7 micrograms per square centimeter, a Maximum Foam Volume of greater than about 100 mL, and combinations of two or more thereof. Also provided are methods of cleaning the skin using the compositions, and methods of promoting products comprising the compositions having high foaming and/or high deposition properties.

An aqueous structured surfactant composition, contains water, one or more anionic surfactants, and one or more amine oxides, and exhibits shear-thinning viscosity, is capable of suspending water insoluble or partially water soluble components, and uses a low relative amount of structuring agent and/or surfactant.

An adhesive composition comprises at least a binder polymer and a water-soluble plasticizer. The binder polymer may be present in a range of about 10% to about 60% by weight of the adhesive composition, and the plasticizer may be present in the range of about 5% to about 85% by weight of the adhesive composition, such as in the range of about 40% to about 80% by weight. In some aspects, the adhesive also comprises less than 10% by weight highly-volatile component, such as about 0% to about 5% by weight. The adhesive composition can be utilized in a variety of articles, including personal care articles, health/medical articles, and household/industrial articles.

An efficient, in-line method for forming an elastic laminate is provided. To form the laminate, a polymer composition containing an elastomeric polymer is extruded as a film. In one embodiment, the film is uniaxially oriented in the machine direction ("MD"), or optionally, biaxially oriented in the machine direction and the cross-machine direction ("CD"). Regardless, the elastic film is then laminated to a nonwoven web material. Prior to lamination, the percent stretch of the nonwoven web material is generally no more than 25% when 500 grams-force is applied per 3 inches of the material in either the cross-machine or machine direction. Such a relatively inextensible nonwoven web material may restrict the overall extensibility of the laminate. Thus, to improve extensibility, the resulting laminate is mechanically stretched in the cross-machine and/or machine directions. Extensibility may also be improved by allowing the laminate to relax and retract prior to winding so that the nonwoven web material gathers or forms buckles.

Biomolecular conjugates are provided which comprise the conjugation product of a repeat sequence protein polymer and at least one active agent. Additional aspects provide methods for their manufacture and various industrial and consumer applications.

A self-stabilizing dispersion composition having a copolymer having at least one polymerizable acid-containing moiety, wherein the at least one acid-containing moiety is at least partially neutralized before or during polymerization, and at least one hydrophobic moiety. A process for producing such compositions is also provided, as well as a process for encapsulating water-insoluble actives in such copolymers.

The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic acid molecules encoding said proteases. Also provided are vectors and host cells including nucleic acid sequences coding for the proteases, methods for producing the proteases, enzyme compositions and methods employing said proteases.

A cationic oil-in-water emulsion for addition to detersive compositions comprising a hydrophilic cationic polymer, an oil-soluble anionic polymer, and a hydrophobic benefit agent in the oil phase made by adding the benefit agent to a hydrophobic liquid; thickening the oil phase with an organophillic smectite clay reacted at clay platelet surfaces to make the clay platelet surfaces hydrophobic while the edge surfaces of the clay remain hydrophilic, such that the benefit agent is adsorbed at an oil/water interface in the emulsion, wherein the anionic polymer is capable of adsorbing the hydrophobic benefit agent at an oil/water interface of the emulsion, and the a hydrophilic, cationic polymer has a cationic nitrogen content of at least 6% by weight, that is incompatible with anionic surfactants, being insoluble in anionic-surfactant solutions containing an amount of 3% or higher of an anionic surfactant, and the hydrophilic cationic polymer has a cationic nitrogen content of at least 0.1% by weight and has a molecular weight of at least 600,000 Dalton.

A fragrance composition useful for imparting fragrance to a surface comprises water, a fragrance material, a liquid crystal-forming material containing at least one fatty alcohol having at least 22 carbon atoms, and a reinforcing material. The compositions are unusually storage-stable, even at high temperatures.

An applicator apparatus includes a non-liquid composition of at least one of an underarm antiperspirant and an underarm deodorant. A barrel at least partially contains the composition. The apparatus includes means for progressively raising the composition through an outlet of the barrel including means for indicating a remaining amount of the composition.

The present invention relates to beta-peptoids with antimicrobial activity. The present invention also relates to methods of producing .beta.-peptoids. The antimicrobial .beta.-peptoids of the invention are useful in pharmaceutical, healthcare, medical device, industrial, food, agricultural, and personal care applications.

The present invention relates to highly disperse precipitated silicas which exhibit an extremely high level of reinforcement of rubber vulcanizates, to a process for their preparation, and to their use as filler for rubber mixtures.

The present invention relates to a cosmetic and personal care preparation or formulation comprising (a) from 0.0001 to 90% by weight of a gloss pigment comprising (a1) a core consisting of a substantially transparent or metallically reflecting material, and (a2) at least one coating substantially consisting of one or more silicon oxides, the molar ratio of oxygen to silicon being on average from 0.03 to 0.95 and (b) from 10 to 99. 9999% of a (cosmetically) suitable carrier material, based on the total weight of the cosmetic preparation or formulation.

A composition for controlled release of an active material such as a fragrance, sunscreen, vitamin or biocide in a product such as a hair shampoo, shower gel, another personal product such as an antiperspirant or deodorant, a household cleaning product such as a laundry detergent, hard surface cleaner or polishes, or a fabric softener, air freshener or tumble drier sheet, comprises a blend of the active material and a waxy cyclopolysiloxane. The cyclopolysiloxane is preferably substituted by hydrocarbon substituents having 12 or more carbon atoms and may also contain an aryl or aralkyl substituent.

Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care formulations and suspensions are provided. Uncoated calcium silicate exhibits a high pH level that may have a deleterious effect upon such cosmetic and/or personal care compositions, thereby rendering the overall composition ineffective for its intended purpose, particularly if the calcium silicate is present in its usual state at high loading levels. Alternatively, if certain materials present within personal care compositions exhibit a sufficiently low pH level, the effectiveness of such calcium silicates may be compromised as well. Such novel coated/treated calcium silicates thus permit high loadings of this beneficial odor neutralizing/sebum absorbing additive within cosmetic and/or personal care formulations without causing any appreciable instability issues or viscosity modification concerns or allow for coexistence with such low pH materials without any appreciable reduction in performance capabilities of the calcium silicates themselves. Certain personal care compositions comprising these novel coated calcium silicate particulates are encompassed within this invention as well.

The self-inflating article of the present invention contains a self-inflating personal care article contains, an inflatable bladder containing a substrate, at least one rupturable reservoir, a cleansing composition wherein said rupturable reservoir is positioned within the sack of the inflatable bladder. The self-inflating article surprisingly provides effective cleansing benefits to the skin and hair in a convenient, inexpensive, and sanitary manner.

Disclosed is a composition comprising or produced from nanoparticle-sized TiO.sub.2, an ethylene copolymer or ionomer of the ethylene copolymer, and optionally a second polymer. Also disclosed are films and other shaped articles produced therefrom. The composition, possessing a UV light barrier, can be used to protect the products that may be susceptible to UV such as foodstuffs.

The present invention relates to photostable compositions that provide protection from ultraviolet radiation ("UVR"). The invention particularly relates to the sunscreens avobenzone, octocrylene and oxybenzone, forming a triplet combination. Compositions of the present invention are free of diesters or polyesters of naphthalene dicarboxylic acid and also are substantially free of substantial amounts of other sunscreens and substantial amounts of optimizing agents. Sunscreens of the invention may be essentially free of, or free of, lower monohydric alcohol and/or acrylates/C.sub.12-22 alkylmethacrylate copolymer in an effective non-pilling amount used to gel a C.sub.1-C.sub.4 alcohol. The triplet combination surprisingly provides and substantially maintains the initial SPF value of the sunscreen composition throughout the period of UVR exposure. Compositions of the invention are photostable such that each of sunscreen active in the triplet combination does not appreciably photodegrade. The present invention accurately communicates the amount of UVR photoprotection actually provided in natural sunlight.

Topical personal care compositions comprising an anti-inflammatory agent, an amphoteric surfactant, a bodifier/humectant, and water and methods of use are disclosed.

Improved methods for the production of multimeric-protein-complexes, such as redox proteins and immunoglobulins, in association with oil bodies are described. The redox protein is enzymatically active when prepared in association with the oil bodies. Also provided are related nucleic acids, proteins, cells, plants, and compositions.

A rinsable personal care composition includes (a) 0 to 75 weight percent of a composition surfactant; (b) 0.01 to 99 weight percent of a skin benefit agent or emollient; (c) 0.01 to 20 weight percent of a hydrophobically modified non-platelet particle; and (d) 0 to 99% water.

This invention relates to non-uniformly substituted ("blocky") hydroxyethylcelluloses (HECs) and derivatives thereof that exhibit associative behavior in both neat solutions and in filled systems. The HECs and derivatives thereof exhibit unique and highly desirable rheology and are more efficient in thickening aqueous systems than prior art HEC products. These blocky HECs can be distinguished from prior art and commercial HEC products by having an unsubstituted anhydroglucose trimer ratio (U3R) greater than 0.21 and the hydroxethyl molar substitution greater than about 1.3 and less than about 5. This invention also relates to processes for making blocky HEC and uses thereof in functional systems.

The use of 2,4--bis(alkylamino)pyrimidines of formula (1) R.sub.1 is C.sub.1-C.sub.12alkyl or C.sub.6-C.sub.10laryl; R.sub.2 is hydrogen or C.sub.1-C.sub.12alkyl; or R.sub.1 and R.sub.2 together form a radical of formula (1a) R' and R'' are each independently of the other hydrogen, C.sub.1-C.sub.6alkyl or C.sub.1-C.sub.6alkoxy, R.sub.3 and R.sub.5 are each independently of the other hydrogen or C.sub.1-C.sub.8alkyl; R.sub.4 is C.sub.1-C.sub.20alkyl, unsubstituted phenyl, C.sub.6-C.sub.10aryl, C.sub.6-C.sub.10aryl--C.sub.1-C.sub.6alkyl, hydroxy--C.sub.1-C.sub.6alkyl, di--C.sub.1-C.sub.6al--ky--lamino--C .sub.1-C.sub.6alkyl, mono--C.sub.1-C.sub.6alkylamino--C.sub.1-C.sub.6alkyl,--(CH.sub.2)2--(O--- (CH.sub.2).sub.2).sub.1--.sub.4-OH or --(CH.sub.2).sub.2-(O--(CH.sub.2).sub.2).sub.1--.sub.4-NH.sub.2; R.sub.6 is C.sub.1-C.sub.20alkyl, C.sub.6-C.sub.10aryl, C.sub.6-C.sub.10aryl--C.sub.1-C.sub.6alkyl, hydroxy--C.sub.1-C.sub.6alkyl, di--C.sub.1C.sub.6alkylamino--C.sub.1-C.sub.6alkyl, mono--C.sub.1-C.sub.6alkylamino--C.sub.1-C .sub.6alkyl, --(CH.sub.2).sub.2-(O--(CH.sub.2).sub.2).sub.1--.sub.4-OH or --(CH.sub.2).sub.2-(O--(CH.sub.2).sub.2).sub.1--.sub.4-NH.sub.2; or R.sub.3 and R .sub.4 and/or R.sub.5 and R.sub.6, together form a pyrrolidine, piperidine, hexamethyleneimine or morpholine ring; in the antimicrobial treatment of surfaces.

Provided are compositions comprising a hydrophobically-modified acrylic polymer, sodium trideceth sulfate, and one or more particles suspended therein having unexpectedly high stability. Also provided are methods of suspending at least one particle comprising combining at least one particle with a hydrophobically-modified acrylic polymer and sodium trideceth sulfate to produce a composition comprising the hydrophobically-modified acrylic polymer and sodium trideceth sulfate in which the at least one particle is suspended.

Novel methods for measuring the soothing attributes of personal care compositions are disclosed. The methods disclosed are particularly suitable for measuring and comparing the soothing attributes of facial tissue to determine which facial tissue is most soothing to damaged skin. The methods include damaging the skin of a test subject to a predetermined amount, contacting a test facial tissue with the damaged skin, and rating the soothing attributes of the facial tissue. In a preferred embodiment, the amount of skin damage on the skin is determined by the test subject.

A multi-liquid phase composition wherein said phases are visually distinctive. These compositions combine multiple phases for creating personal care compositions.

This invention relates to water-soluble hydroxyethylcelluloses (HECs) and derivatives thereof having a hydroxyethyl molar substitution (HE-MS) from about 0.7 to 1.3. These HECs are more efficient in thickening aqueous systems than prior art HEC products and show unique rheology in low water activity systems. These HECs can be distinguished from prior art and commercial HEC products by having an unsubstituted anhydroglucose trimer ratio (U3R) less than 0.21 and a water solubility greater than 90 wt %. This invention also relates to a unique continuous caustic reduction hydroxyethylation process for making the water-soluble, lowly substituted HECs and uses thereof in functional systems.

This invention relates to polyolefin compositions. In particular, the invention pertains to elastic polymer compositions that can be more easily processed on cast film lines, extrusion lamination or coating lines due to improved resistance to draw resonance. The compositions of the present invention preferably comprise an elastomeric polyolefin resin and a high pressure low density type resin.

A resin composition is prepared by reacting components comprising dibasic acid, diamine, polyol and monoalcohol, wherein (a) at least 50 equivalent percent of the dibasic acid comprises polymerized fatty acid; (b) at least 50 equivalent percent of the diamine comprises ethylene diamine; (c) 10-60 equivalent percent of the total of the hydroxyl and amine equivalents provided by diamine, polyol and monoalcohol are provided by monoalcohol; and (d) no more than 50 equivalent percent of the total of the hydroxyl and amine equivalents provided by diamine, polyol and monoalcohol are provided by polyol. This resin composition may be formulated into, for example, personal care products, fragrance releasing products and candles.

The invention provides a method of producing a personal care product comprising combining a fragrance, a propellant and porous carrier particles, to produce a composition substantially free of pre-encapsulated fragrance particles, and containing the composition in a pressurized container. Also provided is a personal care product comprising a pressurized container and a composition contained therein, which includes a fragrance, a propellant and porous carrier particles, wherein the composition is substantially free pre-encapsulated fragrance particles. When the composition is released from the container, the propellant evaporates rapidly to produce a matrix, which incorporates the fragrance into the pores of the carrier, to produce a sustained-release fragrance delivery system.

Multi-phase personal care compositions comprise a first phase and a second phase, wherein said first and second phases form a visually distinct pattern. The compositions are intended for moisturizing or conditioning skin or hair and comprise less than about 10%, by weight of the multi-phase personal care composition, of surfactant. Methods of moisturizing or conditioning skin or hair comprise the steps of wetting the skin or hair, applying the multi-phase personal care composition to the skin or hair, and rinsing the multi-phase personal care composition from the skin or hair. A process for making the multi-phase personal care composition comprises forming a first phase by premixing an oil/emollient benefit agent and oil-soluble colorant and then combining the premix with additional optional ingredients.

A process for obtaining oils of sesquiterpenes and sesquilactones and (-)-guaiol from the oil of Callitris intratropica, processes for encapsulation of the oil from Callitris intratropica, and the various uses of the oil and the encapsulated oil are described. The oils are suitable for various purposes in the personal care field, e.g. for the antimicrobial treatment of skin, mucosa and hair and of textile fibre materials, as an antimycotic against skin fungi and moulds, as an anti-inflammatory, as an acaricide against house dust mites and ticks, and for preserving cosmetic products.

Peptides have been identified that bind with high affinity to body surfaces, such as, hair, skin, nails, teeth, gums, and oral cavity surfaces. Diblock and triblock peptide-based body surface coloring reagents formed by coupling a body surface binding peptide to a pigment binding peptide, either directly or through a spacer, are described. The peptide-based body surface coloring reagents may be used in conjunction with pigments to color body surfaces.

The present invention relates to crosslinked protein crystals characterized by the ability to change from insoluble and stable form to soluble and active form upon a change in the environment of said crystals, said change being selected from the group consisting of change in temperature, change in pH, change in chemical composition, change from concentrate to dilute form, change in oxidation-reduction potential of the solution, change in the incident radiation, change in transition metal concentration, change in flouride concentration, change in free radical concentration, change in metal chelater concentration, change in shear force acting upon the crystals and combinations thereof. According to one embodiment of this invention, such crosslinked protein crystals are capable of releasing their protein activity at a controlled rate. This invention also provides methods for producing such crosslinked protein crystals, methods using them for protein delivery and methods using them in cleaning agents, including detergents, pharmaceutical compositions, vaccines, personal care compositions, including cosmetics, veterinary compositions, foods, feeds, diagnostics and formulations for decontamination.

Personal care composition in the form of a dry film useful in cleansing or shaving. The film includes at least one water soluble polymer in an amount of about 45 to about 82 weight %, based on total weight of dry film, and, when used for cleansing, at least one surfactant in an amount of about 18 to about 55 weight %; based on total weight of dry film. The at least one water soluble polymer can include blends of polymers. Other additional ingredients for use in the film include plasticizers and/or neutralizing agents. The personal cleansing dissolvable films provide improved aesthetics, foaming, cleansing, moisturizing and lubricity.

Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R.sub.1 is hydrogen, C.sub.1-C.sub.20alkyl; C.sub.1-C.sub.20alkoxy; CF.sub.3; C.sub.6-C.sub.10aryl; or a radical of formula (1a) and R.sub.2 is hydrogen; or C.sub.1-C.sub.20alkyl. The compounds are used as antimicrobial actives for the treatment of surfaces.

A rinsable personal care composition comprises (a) 0 to 75 weight percent of a surfactant; (b) 0.01 to 99 weight percent of a skin benefit agent comprising a high modulus lipid and an ester; and (c) 0 to 99 weight percent water.

Stable personal care composition comprising hydrophobic modified silica, a particulate material and a dermatologically-acceptable carrier, said carrier comprising about 70% or greater, by weight of the carrier, of at least one water-soluble polyol, said water-soluble polyol having a solubility parameter of from about 11 to about 17.

A polymeric substrate primed with a treatment composition to allow better receptivity of an ink composition, and method for making the same, is generally disclosed. More specifically, the polymeric substrate can be a hydrophobic polymeric substrate such as comprising polyolefins, which exhibits better ink adhesion and rub resistance when pretreated with a treatment composition of the present invention.

The present invention is directed to elastic webs, such as elastic films and elastomeric fibrous meltblown or spunbond webs which may include elastomeric fibers and/or elastomeric continuous filaments. The elastic webs include an elastomeric block copolymer and an amorphous polyolefin plastomer wax. The elastic webs may include a tackifier, but desirably they do not. The elastic webs of the present invention may display hysteresis values and/or immediate set values upon elongation and retraction less than the hysteresis values and immediate set values of previously known elastic webs of similar basis weight. The elastic webs may display tension values upon elongation less than tension values displayed by previously known elastic webs of similar basis weight. The present invention is also directed to elastic laminate structures comprising at least one layer of an elastic web adhesively bonded to one or more other webs, such as, for instance a woven or nonwoven web.

Provided herein are amphoteric surfactants derived from ethyleneamines, which surfactants are useful in treating paper, fibers, textiles, hair, and human skin, to impart softness-to-the-touch properties thereto.

The present invention is directed to novel capsules containing active materials and methods for making capsules with enhanced performance and stability. The capsules are well suited for use in personal care applications, laundry products and perfume and fragrance products.

A process is provided for preparing a personal care composition, which is based on combining a concentrate comprising neutralising base and surfactant with water and sensory ingredients, functional ingredients or a combination thereof.

A PSA laminate is provided comprising: a) at least one outer filmic layer (A) comprising at least one filmic polymer; b) at least one adhesive base layer (B) comprising at least one adhesive base polymer; and c) at least one tackifier layer (C) comprising at least one tackifier; wherein the pressure sensitive adhesive laminate is obtainable by co-extruding the outer filmic layer (A) with the adhesive base layer (B) to produce a non-adhesive laminate and applying the tackifier layer (C) to the adhesive base layer side of the non-adhesive laminate to produce the PSA laminate.

A mild, multiphase cleansing composition is described that includes a structured surfactant component has a first density; a benefit component that has a second density; and a density modifier; wherein the first density differs from the second density by less than 0.15 g/cm.sup.3; the structured surfactant component includes at least one surfactant and provides a Total Lather Volume of at least about 600 ml.

The present invention relates to precipitated silicas which have extremely low microporosity and high rubber activity, to a process for their preparation, and to their use as filler for rubber mixtures.

Babassuamadopropalkonium chloride is quaternary ammonium compounds obtained from natural babassu oil that contains a high level of lauric acid, and it has been used as mild conditioner. We found that babassuamadopropalkonium chloride has strong and broad-spectrum antimicrobial activity especially with bisabolol. Bisabolol is the active component of Chamomile, one of the most used medical plants, and has been used as anti-irritant. We found that there is a synergistic effect of bisabolol on hinokitiol, when combined with ethylhexylglycerin or caprylyl glycol. This synergistic effect of composition of bisabolol and ethylhexylglycerin can reduce the required amount of hinokitiol, which if used in high amount can be unstable by more than 100 times. Self-preserving personal care cleansing compositions that include bisabolol, alkyl or alkylamidopropyl betaines, amphoteric surfactants, acyl sarcosinates and optionally fatty acids and(or) acyl lactylate and(or) acyl glucoside and(or) babassuamadopropalkonium chloride and colloidal silver have also broad-spectrum antimicrobial activity.

Provided are compositions comprising low molecular weight polymeric materials and surfactants having reduced irritation associated therewith, methods of reducing the irritation associated with a personal care composition comprising an anionic and/or amphoteric surfactant, the methods comprising combining a low molecular weight polymeric material capable of binding a surfactant thereto with an anionic surfactant to produce a reduced irritation personal care composition, and methods of using such compositions to cleanse the hair or skin with reduced irritation.

A composition suitable for use in personal cleaning or detergent soap, which includes a sulfonated fatty acid and/or alpha sulfonated alkyl ester, and methods for producing such a composition. The composition and methods exhibit efficient processing and allow for formation of cleansing or detergent bars with improved hardness, improved resistance to marring and improved processability to marring, lower wear-rate and decreased mush formation during consumer use.

A valerolactone compound represented by the formula (I): wherein each of R.sup.1 and R.sup.2 is independently a hydrogen atom, a methyl group or an ethyl group wherein when R.sup.1 is a hydrogen atom, R.sup.2 is not a hydrogen atom; and wherein when R.sup.2 is a hydrogen atom, R.sup.1 is not a hydrogen atom, R.sup.3 is a hydrogen atom or a methyl group, and R.sup.4 is a propyl group, a 1-propenyl group or a phenyl group; a valerolactone compound represented by the formula (II): a process for preparing the same; and a perfume composition comprising the above-mentioned valerolactone compound.

A hair care composition comprising i) a polymer comprising an ABA block copolymer, wherein the A groups are poly(aminoalkylmethacrylate) blocks and the B group is derived from an ethylenically unsaturated carboxylate and, ii) a cosmetically acceptable diluent or carrier.

Personal care compositions containing diethylhexyl syringylidene malonate are provided. Methods for regulating the condition of mammalian keratinous tissue by topically applying the personal care compositions are also provided.

Compositions useful for regulating the condition of mammalian keratinous tissue needing such treatments are provided. An exemplary composition comprises a safe and effective amount of glycyrrhizic acid and/or glycyrrhetinic acid; a safe and effective amount of an active selected from the group consisting of N-acyl amino acid compounds, hexamidine, cetyl pyridinium chloride, ergothioneine, and combinations thereof, and a dermatologically acceptable carrier.

According to the invention, a solid encapsulate is provided comprising: (a) an oil phase; (b) a water-soluble emulsification polymer, wherein a 0.1 %wt aqueous solution of the water-soluble emulsification polymer has a surface tension of 15-60 mN/m (15-60 dynes/cm) when measured at 25.degree. C.; (c) a water-soluble film-forming polymer; wherein the water-soluble emulsification polymer is different from the water-soluble film-forming polymer.

A PSA laminate is provided comprising: a) at least one outer filmic layer (A) comprising at least one filmic polymer; b) at least one adhesive base layer (B) comprising at least one adhesive base polymer; and c) at least one tackifier layer (C) comprising at least one tackifier and at least one polymer; wherein the pressure sensitive adhesive laminate is obtainable by co-extruding the outer filmic layer (A) with the adhesive base layer (B) to produce a non-adhesive laminate and applying the tackifier layer (C) to the adhesive base layer side of the non-adhesive laminate to produce the PSA laminate. Processes for producing the PSA laminate, and articles comprising the PSA laminate are also provided.

Substantive silicone emulsions are disclosed containing a combination of polydimethylsiloxane and pyrrolidone carboxylic acid dimethylsiloxane copolymer. The emulsions are added to personal care compositions for the hair and skin to provide, smoothness, gloss and a conditioning feel to the user.

The present invention provides compositions that include (a) a warming agent or a cooling agent and (b) a silicone-containing component. Also provided is a method of increasing the warming effect of a warming agent or the cooling effect of a cooling agent by adding a silicone-containing component to a topical composition containing the warming agent or cooling agent.

A cleansing cosmetic composition comprising; i) a cationised silicon delivery system selected from one or more of a) a cationised fatty alkyl silicone copolymer; b) a cationised dimethiconol complex and c) a cationised high viscosity lower alkyl silicone fluid with or without cationised silicone gum blend; and ii) detergent active. Also disclosed is a cationised silicone delivery system comprising: a) 15-50 parts of a cationised fatty alkyl silicone copolymer; b) 5-50 parts of a cationised dimethiconol complex; and c) 1-50 parts of a cationised high viscosity lower alkyl silicone fluid with cationised silicone gum blend.

A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C.sub.5-C.sub.42)alkyl-polyether radical per molecule, wherein the bicycloheptyl- or bicycloheptenyl- polyether radical may optionally be substituted on one or more of the ring carbon atoms by one or two (C.sub.1-C.sub.6)alkyl groups per ring carbon atom is useful in making polymers, particularly pH responsive polymers.

Surfactant-containing compositions are described which include a protein component that has the effect of improving the surface-active properties of the surfactants contained in the compositions. The surfactant-containing compositions having the protein component demonstrate significantly lower critical micelle concentrations (CMC), reduced surface tensions, and reduced interfacial tensions than do comparable compositions having no protein component. In addition, the surfactant-containing compositions having the protein component has the effect of converting greasy waste contaminants to surface active materials.

An aqueous structured surfactant composition, contains water, one or more anionic surfactants, and one or more alkoxylated nonionic surfactants, wherein at least one alkoxyl unit per molecule of the alkoxylated nonionic surfactants is a propoxyl unit or a butoxyl unit, exhibits shear-thinning viscosity, is capable of suspending water insoluble or partially water soluble components, and is mild to the eyes and skin.

Menthol propyleneglycol-carbonate, analogs thereof and compositions containing such compounds are useful as insect repellents.

A multi-phase personal care composition is described that comprises a first visually distinct phase including a structured surfactant component and a second visually distinct phase. The structured surfactant component comprises at least one branched anionic surfactant and from 0 to 10% by weight of the first visually distinct phase, of sodium trideceth sulfate.

A small-granule aluminum starch octenylsuccinate (ASO) derivative having a distribution of starch granules with a mean diameter of between 4.5 .mu.m and 8.9 .mu.m is disclosed herein. The small-granule ASO may be used in a wide variety of personal care formulations.

The present invention discloses a method for making cationic, aminofunctional silicone emulsions particularly cationic emulsions having a low volatile cyclic siloxane content. The method of the present invention comprises an acid catalyzed emulsion condensation reaction of a mixture comprising hydroxy terminated polydimethylsiloxane and an aminosilane under conditions that do not allow for the generation of equilibrium cyclic oligomers followed by conversion to a cationic emulsion.

The present invention is drawn to a carrier composition containing: (a) at least one fatty monoamine compound; (b) at least one nonionic surfactant; (c) at least one anionic silicone; and (d) at least one water-insoluble material, and wherein the composition, when combined with an aqueous phase, forms an aqueous delivery system which is both stable, and clear to slightly hazy/limpid in appearance.

The present invention is drawn to a carrier composition containing: (a) at least one fatty quaternary amine compound; (b) at least one nonionic surfactant; (c) at least one anionic silicone; and (d) at least one water-insoluble material, and wherein the composition, when combined with an aqueous phase, forms an aqueous delivery system which is both stable, and clear to slightly hazy/limpid in appearance.

The present invention is drawn to a carrier composition containing: (a) at least one polyamine compound comprising at least two amino groups; (b) at least one nonionic surfactant; (c) at least one anionic silicone; and (d) at least one water-insoluble material, and wherein the composition, when combined with an aqueous phase, forms an aqueous delivery system which is both stable, and clear to slightly hazy/limpid in appearance.

Starch-lipid composites are prepared by heat treatment of thermally stable granular starch with lipids under controlled conditions. The granular starch-lipid composites display unique properties including excellent cold and hot water swelling characteristics and the formation of stable emulsions. The products are useful as dispersing agents, thickening agents, fat substitutes and carriers for lipid-soluble active ingredients in foods, personal care and pharmaceutical applications.

Mineral-bound starch products are provided for enhanced absorption of nutrient minerals. The mineral-bound starch products are prepared by binding biologically active minerals to phosphorylated cross-linked starch. The mineral-bound starch products are stable against heating in hot water followed by washing processes, but able to release bound minerals after digestion.

Described are bottle(s) comprising polyesters comprising (a) a dicarboxylicacidcomponent comprising terephthalic acid residues; optionally, aromatic dicarboxylic acid or aliphatic dicarboxylic acid residues; 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; and 1,4-cyclohexanedimethanol residues.

A polymeric encapsulated fragrance is disclosed which is suitable for use in personal care and cleaning products. In a preferred embodiment of the invention the fragrance is encapsulated by a first polymer material to form a fragrance encapsulated polymer, the polymer encapsulated shell is then coated with a cationic polymer, preferably a cationic starch and guar.

A process for making high specific viscosity copolymers of maleic anhydride and an alkyl vinyl ether by copolymerizing maleic anhydride and an alkyl vinyl ether monomers in the presence of added acetylene.

Described are polyester compositions comprising (a) a dicarboxylic acid component comprising terephthalic acid residues; optionally, aromatic dicarboxylic acid or aliphatic dicarboxylic acid residues; 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues, wherein said 2,2,4,4-tetramethyl-1,3-cyclobutanediol contains certain cis to trans ratios; and 1,4-cyclohexanedimethanol residues.

Described are polyester compositions comprising (a) a dicarboxylic acid component comprising terephthalic acid residues; optionally, aromatic dicarboxylic acid or aliphatic dicarboxylic acid residues; minimal amounts of 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; ethylene glycol, and optionally, 1,4-cyclohexanedimethanol residues.

The present invention is drawn to a carrier composition containing: (a) at least one phospholipid; (b) at least one nonionic surfactant; (c) at least one anionic silicone; and (d) at least one water-insoluble material, and wherein the composition, when combined with an aqueous phase, forms an aqueous delivery system which is both stable, and clear to slightly hazy/limpid in appearance.

A polymeric encapsulated fragrance is disclosed which is suitable for use in personal care and cleaning products. In a preferred embodiment of the invention, the fragrance is encapsulated by a first polymer material to form a fragrance encapsulated polymer, the polymer encapsulated shell is then coated with a mixture of cationic polymers, in a preferred embodiment the coating polymers are a reaction product of polyamines (including 1H-imidazole) and (chloromethyl) oxirane or (bromomethyl) oxirane.

Disclosed is a lipophilic personal care composition comprising by weight: (a) from about 5% to about 50% of an N-long chain acyl acidic amino acid ester of sterol which is liquid at 25.degree. C. having formula (I): XOC(O)--(CH.sub.2).sub.n--CH(NHCOR)--C(O)OY (I) wherein one of X and Y is an ester residue of sterol, and the other is selected from H, a liquid alkyl or alkenyl of 8-30 carbons, and ester residue of monohydric solid alcohol of 12-38 carbons; COR is a long chain acyl group of 8-22 carbons; and n is an integer of 1 or 2, and (b) from about 0.5% to about 15% of an acryl alkyl silicone copolymer having a melting point of no more than about 40.degree. C.

Personal care compositions comprising a desirable rheology profile. A method of delivering benefits to hair or skin is provided.

Personal care composition comprising an effective amount of a zinc containing material; a surfactant; a cationic, or a nonionic thickening polymer, or a mixture thereof. The present invention may be a multi-phase personal care composition comprising: at least two phases wherein at least one of the phases comprises an effective amount of a zinc containing material, at least one surfactant, and at least one cationic or nonionic thickening polymer, or a mixture thereof, and the at least two phases are visually distinct phases that are packaged in physical contact and maintain stability. In the present invention, the at least one cationic or nonionic thickening polymers, or mixtures thereof, does not bind completely to the zinc ions from the zinc containing material.

Personal care composition comprising from about 0.05% to about 5% of at least one aquaporin-stimulating compound selected from the group consisting of xanthine, caffeine; 2-amino-6-methyl-mercaptopurine; 1-methyl xanthine; 2-aminopurine; theophylline; theobromine; adenine; adenosine; kinetin; p-chlorophenoxyacetic acid; 2,4-dichlorophenoxyacetic acid; indole-3-butyric acid; indole-3-acetic acid methyl ester; beta-naphthoxyacetic acid; 2,3,5-triiodobenzoic acid; adenine hemisulfate; n-benzyl-9-(2-tetrahydropyranyl)adenine; 1,3-diphenylurea; 1-phenyl-3-(1,2,3-thiadiazol-5-yl)urea; zeatin; indole-3-acetic acid; 6-benzylaminopurine; alpha-napthaleneacetic acid; 6-2-furoylaminopurine; green tea extract; white tea extract; menthol; tea tree oil; ginsenoside-RB1; ginsenoside-RB3; ginsenoside-RC; ginsenoside-RD; ginsenoside-RE; ginsenoside-RG1; ginseng root extract; ginseng flower extract; pomegranate extract, extracts from Ajuga turkestanica; extracts from viola tricolor and combinations thereof; an additional ingredient selected from the group consisting of niacinamide, glycerin and mixtures thereof, and a dermatologically-acceptable carrier.

The present invention is directed to ion triggerable, water-dispersible cationic polymers. The present invention is also directed to a method of making ion triggerable, water-dispersible cationic polymers and their applicability as binder compositions. The present invention is further directed to fiber-containing fabrics and webs comprising ion triggerable, water-dispersible binder compositions and their applicability in water-dispersible personal care products, such as wet wipes.

What is described herein is a neutral pH, VOC-free biocidal composition of 1,2-benzisothiazolin-3-one which is stable at low temperatures for an extended period of time. The compositions are particularly advantageous in use in protecting latex, paint, coating, cosmetic and personal care formulations against microbiological spoilage.

Multi-phase personal care compositions comprising: (a) at least one personal care composition phase; and (b) at least one another personal care composition phase; wherein the phase (a) and said the phase (b) are visually distinct phases that are packaged in physical contact, wherein the phase (a) and the phase (b) have a yield stress of from about 1 Pa to about 100 Pa, and wherein the viscosity ratio of the phase (a) to the phase (b) is from about 1:15 to about 15:1 at shear stress over the yield stress of the phases (a) and (b) up to at least 200 Pa. By matching rheology profiles of each phase compositions in such kinetic conditions, desired patterns of multi-phase personal care compositions are easily obtained and/or maintained for a longer period of time.

Personal care compositions comprising a dipeptide and methods of using such compositions to treat the condition of keratinous tissue. The C terminal amino acid of said dipeptide is threonine. The personal care composition can be applied topically, ingested orally, injected, or used as part of a combined treatment regimen.

A polymer that includes at least one monomeric unit having a pendant substituent group according to formula (II): wherein:R.sup.1 is H, chloro, bromo, alkyl, hydroxyalkyl, aryl, or aralkyl, R.sup.2 and R.sup.3 are each independently H, alkyl, hydroxyalkyl, aryl, aralkyl, uriedo, or carboxyalkylene, R.sup.4 is alkylene or R.sup.5, R.sup.7, and R.sup.10 are each independently alkylene, R.sup.6, R.sup.8, and R.sup.9 are each independently H or alkyl, A is O or N--R.sup.11, provided if A is O and R.sup.4 is methylene, then R.sup.1 cannot be H, chloro, or bromo, R.sup.11 is H or alkyl, and X.sup.- is an anion, is useful in personal care application, such as hair stying compositions.

Benzoquinone compositions of enhanced solubility and bioavailability are described that contain at least one benzoquinone with at least one solubility-enhancing polymer. In one embodiment, the benzoquinone is coenzyme Q1O. Described methods to produce the bioenhanced products comprise dry blending and solvent spray drying. One aspect of the method includes the steps of providing a mixture comprising benzoquinone, a solubility-enhancing polymer and a solvent and removing the solvent to form amorphous benzoquinone. Products made by the invention's compositions and methods include pharmaceuticals, nutraceuticals, cosmetic, and personal care products for man and animal.

A mild, aqueous, liquid crystalline structured cleansing and moisturizing composition with low levels of surfactants that include monoalkyl sulfosuccinate surfactant(s) and high levels of hydrophillic emollients is provided that provides a low in-use slip, tight skin feel, and a fast, clean-feel rinse in the absence of substantial levels of soap. Substantial amounts of persistent and fine quality lather are produced with the inventive composition even in the presence of high levels of emollients.

Personal care compositions comprise (a) from 0.05-0.5% of a first non-guar cationic polymer having a mean charge density from 0.2 to 0.85 meq/g, (b) from 0.05-0.4% of a second non-guar cationic polymer having a mean charge density from 1.0 to 7.0 meq/g, (c) from about 5 wt. % to about 50 wt. % of an anionic surfactant system, said anionic surfactant system comprising at least one anionic surfactant and having an ethoxylate level and an anion level, i) wherein said ethoxylate level is from about 2 to about 6, and ii) wherein said anion level is from about 1 to about 4; and (d) at least about 20 wt. % of an aqueous carrier.

Use of a liquid composition comprising at least two agents selected from lactic acid, salicylic acid, benzyl alcohol, and/or low molecular weight aliphatic alcohol having less than five carbon atoms for the manufacture of an antimicrobial solution is disclosed. In a preferred embodiment, the antimicrobial solution is formulated as a teat dip for lactating animals, particularly cows. The composition may be used as a prophylactic treatment or for wound healing, and is particularly useful against mastitis. The antimicrobial compositions may be used in personal care, hard surface care including hard surface disinfection in households, food processing, hospitals, restaurants, hotels, showers, or topically as hand soaps, surgical scrubs, and hoof disease mitigators.

A polymer comprising, based on the total number of monomeric units of the polymer, greater than 50% monomeric units that comprise, per monomeric unit, at least one pendant poly(alkyleneoxy) substituent group according to formula (I): wherein:each R.sup.1 is independently H, methyl or ethyl, each R.sup.2 is independently H or (C.sub.1-C.sub.6)alkyl, each n is independently an integer of from about 5 to about 500, and exhibiting a weight average molecular weight of from about 1,000 to about 1,000,000 grams per mole is useful in personal care applications.

A method for an oxidatively stable cuphea derived emollient composition having a relatively high capric acid concentration is disclosed. Various features and specifications may be controlled, adapted or otherwise modified to improve the application and utilization of cuphea oil and cuphea oil derivatives as emollients. The present invention generally provides cosmetic, personal care and other topical preparation ingredients having improved oxidative stability as well as other desirable characteristics as compared with naturally derived emollient and/or synthetic emollient alternatives.

Methods and compositions--particularly compositions containing .beta.-carotene--for modulating the expression of genes that effect or influence cellular health or protect against cellular damage, e.g., skin aging, are provided. More particularly, a method is provided for screening for a compound that modulates an effect of UV irradiation on eukaryotic cells. Methods and compositions for ameliorating the effects of non-UV radiation induced skin aging and for modulating UVA-induced gene expression on skin aging are also provided. Further provided are methods and compositions for enhancing UVA-induced tanning of the skin, for promoting cell differentiation in UVA-irradiated cells of an organism, and for modulating stress-induced induction of a gene in an organism.

A cellulose ether which has from 4,000 to 10.000 anhydroglucose repeat units and is substituted with (a) on the average from 0.0003 to 0.08 moles, per mole of anhydroglucose unit, of a substituent comprising an alkyl or arylalkyl group having from 8 to 24 carbon atoms and (b) a substituent having the formula II wherein R.sup.5, R.sup.6 and R.sup.7 each independently are --CH.sub.3 or --C.sub.2H.sub.5, R.sup.8 is --CH.sub.2--CHOH--CH.sub.2-- or --CH.sub.2CH.sub.2, A.sup.z- is an anion, and z is 1, 2 or 3 is useful in hair and skin care compositions.

In an extraction process comprising extracting a raw extract from Emblica officinalis the improvement comprising conducting the extraction under conditions of time, temperature and atmosphere, to inhibit the formation of black specks and/or oligomeric and/or polymeric tannins and/or oxidation products thereof.

A composition is provided that may include the product of a first material having a low-temperature fluidity point including a first functional group; and, a second material including a second functional group. The first functional group can interact with the second functional group below a threshold temperature to form a product having a viscosity greater than the viscosity of the first material or of the second material.

Preservative compositions are provided with improved stability. The preservative compositions comprise a combination of an amphoteric compound and 3-iodo-2-propynyl butyl carbamate (IPBC). In a particular embodiment, the compositions comprise a combination of a betaine compound and 3-iodo-2-propynyl butyl carbamate. The compositions in some embodiments have surprising stability. The preservative composition can be used in personal care products, household products, industrial products and materials. The compositions can be used in a variety of methods for the treatment of surfaces such as cellulosic surfaces, such as wood surfaces. The compositions can be used in one embodiment to provide stain resistance to wood.

High-viscosity elastomeric adhesive compositions including a high softening point tackifier resin in combination with a base polymer can be used to create elastomeric composite laminates having effective adhesion and elastic properties. The elastomeric adhesive compositions suitably have a viscosity between about 100,000 and about 500,000 cps at between about 300 degrees Fahrenheit (149 degrees Celsius) and about 350 degrees Fahrenheit (177 degrees Celsius). Facing layers, such as nonwoven webs, films, elastic strands, fastening material, absorbent material, and the like, can be laminated to one or both surfaces of the elastomeric compositions to form elastomeric composite laminates. A method of making such compositions and laminates involves forming the compositions into elastomeric adhesive films and/or strands.

Personal soap bar composition which give users enhanced skin feel benefits through an unexpected synergy between certain quaternary ammonium compounds and free fatty acids.

A personal care cleansing composition having enhanced perceptible skin benefits, for example, by selecting certain ratios of quaternary ammonium compounds and free fatty acids. Additionally, in accordance with various aspects of the present invention, the present inventors have discovered that the addition of talc in varying percentages increases qualities to the user such as freshness, smoothness, lather and creaminess. Additionally, aspects relating to fragrance retention, deposition and the amounts perceived are improved.

Disclosed herein is a cushioned blown film including a first blown film layer, a second blown film layer, and a plurality of cushioning cells defined between the first blown film layer and the second film layer. The cushioned blown films may be bonded to a fibrous web to make film nonwoven laminates. Processes for making the cushioned blown film and the film nonwoven laminates are also disclosed. Such laminates are highly useful for use in personal care products, protective wear garments, medical care products, mortuary and veterinary products and the like.

The present invention relates to the use of cross-linked silicone gel, in particular, a polymerization product of a polyorganohydrosiloxane, with the proposed INCI name (Dimethicone/polymethylalkyl siloxane copolymer), in cosmetic applications to provide unexpected characteristics related to formulations incorporating these silicone gels.

Provided are anti-inflammatory compositions comprising (a) an anti-inflammatory agent selected from the group consisting of olive leaf extract, holly herb, sappan wood, feverfew, and combinations of two or more thereof, and (b) an anti-inflammatory agent comprising at least one lipophilic aminoacid and at least one metal salt. Also provided are personal care products comprising such compositions, and methods of use thereof.

Provided are anti-inflammatory compositions comprising (a) an anti-inflammatory agent selected from the group consisting of olive leaf extract, holly herb, sappan wood, feverfew, and combinations of two or more thereof, and (b) an anti-inflammatory agent comprising at least one lipophilic aminoacid and at least one metal salt. Also provided are personal care products comprising such compositions, and methods of use thereof.

Business method for generating advertising claims by utilizing Confocal Raman Spectroscopy (CRS) for dermatological studies. The methods of the invention can be carried in vitro (either artificial skin or a sample of skin) or in vivo (directly on the human skin of a person).

A personal care composition is provided with a silicone compound and being aesthetically modified for improved skinfeel with a quaternary ammonium salt, the salt having a structure AB, wherein A is a cationic charged component, B is an anionic charged component, and A has one quaternized nitrogen atom, at least two hydroxyl groups and a molecular weight no higher than about 250.

Personal care composition comprising a vitamin B3 compound, a sugar amine, a hydroquinone compound, and a dermatologically-acceptable carrier.

A personal care composition is provided formulated with glycerin and a moisturization enhancing agent which is a salt of structure AB, wherein A is a cationic charged component, B is an anionic charged component, and A has at least one quaternized nitrogen atom and at least two hydroxyl groups and a molecular weight no higher than about 400.

The present invention relates to a water-soluble associative cellulose ether having a DP viscosity from 250 to 20,000 mPas, measured at a concentration of 1% by weight, and a molecular substitution, MS, from 0.0001 to 0.005 of a hydrophobic substituent containing an unsubstituted or substituted hydrocarbon group of 8-24 carbon atoms. The cellulose ether has a good thickening effect and advantageous application properties at low contents and can be used in an aqueous decorative paint composition, an aqueous paper coating composition, an aqueous organic filler composition, an aqueous cement slurry, an aqueous detergent composition or an aqueous personal care formulation.

A method for applying a particulate benefit agent to a body surface is provided. The method employs a particulate benefit agent coated with a polymer. The polymer-coated benefit agent is applied to a body surface such as hair or skin, in the presence of a composition comprising a peptide having affinity for the polymer. The presence of the polymer-binding peptide in the application serves to extend the binding longevity of the coated particulate benefit agent on the body surface.

A personal care composition comprising a perfume booster accord. The human nose can detect the odor of the perfume booster accord at low concentrations. The perfume booster accord also provides a bigger bloom and longevity of scent. The present invention is further directed to a method of using the personal care composition.

A personal cleansing article having a capsule and a liquid cleansing composition contained within the capsule is disclosed. The capsule is made to contain a trigger such that upon the occurrence of a specific event, the liquid cleansing composition is released from the capsule. A method for personal cleansing using such an article is also disclosed. Additionally, a method for manufacturing a foaming liquid cleansing composition is disclosed.

A mild, multi-phase cleansing composition is described that includes a cleansing phase including a structured surfactant component has a first density; a benefit phase includes an emulsion, the benefit phase has a second density and a density modifier; wherein the first density differs from the second density by less than 0.15 g/cm.sup.3; the structured surfactant component includes at least one surfactant and provides a Total Lather Volume of at least about 600 ml. The emulsion is either an oil in water or an oil in water emulsion.

The use of 2-methyl-5-phenyl pentanal is described for producing, modifying or intensifying a rose scent.

The present invention is directed to compositions containing at least a polyphenol and polyethylenglycol, to products such as food, beverages, dietary supplements, feed, pharmaceuticals and personal care products containing such a composition as well as to the use of polyethylenglycol for masking the bitter taste of such polyphenols. The polyphenols are preferably selected from the group consisting of epigallocatechin gallate, resveratrol, hydroxytyrosol, oleuropein, polyphenols present in green tea extracts, catechins, polyphenols present in extracts of red grape skin, polyphenols present in olives and/or olive waste water, and their mixtures.

Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

The present invention relates to spray-dried compositions comprising encapsulated active materials and a spray-dry carrier, to methods for imparting an effective amount of active materials to spray-dried products and to products incorporating the spray-dried compositions.

This invention relates to polyolefin compositions. In particular, the invention pertains to elastic polymer compositions that can be more easily processed on cast film lines, extrusion lamination or coating lines. The compositions of the present invention preferably comprise an elastomeric polyolefin resin and a high pressure low density type resin.

The present invention relates to acrylic block copolymers synthesized by a controlled radical process, and their use as thickeners in oil-based compositions. The acrylic copolymers are especially useful as viscosity index improvers in lubricating oil.

An apparatus for dispensing a personal care composition to the skin includes a container with a reservoir containing the composition. The apparatus has an application end having fibers, with free ends, that provide an application surface.

Compositions comprising an asymmetric disiloxane surfactant composition comprising a silicone composition comprising a silicone having the formula: MM'where M or M' comprises an alkylpolyalkyleneoxide bearing substituent selected from the group consisting of: R.sup.13(C.sub.2H.sub.4O).sub.a(C.sub.3H.sub.6O).sub.b(C.sub.4H.sub.8O).s- ub.cR.sup.14 and R.sup.12SiR.sup.5R.sup.6(R.sup.13(C.sub.2H.sub.4O).sub.a(C.sub.3H.sub.6O)- .sub.b(C.sub.4H.sub.8O).sub.cR.sup.14) that exhibit resistance to hydrolysis over a wide pH range.

Malodour formation reducing compounds alpha-N-(3-Methyl-5-phenylpentanoxycarbonyl)-L-glutamine, alpha-N-(2-Methyl-5-phenylpentanoxycarbonyl)-L-glutamine, and alpha-N-(2,4-Dimethyl-4-phenylbutanoxycarbonyl)-L-glutamine, and their salts, compositions comprising such compounds, including cosmetic products, personal care products, and deodorant products, and methods forming such products and their use. The compounds are useful to reduce the formation of human malodour resulting from bacterial degradation of compounds naturally present in sweat, in particular axilliary malodour.

Disclosed is a skin-protecting alkalinity-controlling composition comprising propylene glycol pectin having a degree of esterification in the range from about 30% to about 100%.

The present invention relates to a supramolecular polymer comprising quadruple hydrogen bonding units within the polymer backbone, wherein at least a monomer comprising a 4H-unit is incorporated in the polymer backbone via at least two reactive groups up to four reactive groups, provided that the 4H-units are not covalently incorporated in the polymer backbone through one or more silicon-carbon bonds. The invention also relates to processes for preparing such supramolecular polymers and their use in personal care applications, surface coatings, imaging technologies, biomedical applications, (thermo)reversible coatings, adhesive and sealing compositions and as thickening agents, gelling agents and binders.

A personal care product includes a container and a personal care composition having visually distinct phases disposed in the container. The container includes a viewing portion that allows for viewing of the visually distinct phases within the container and a covering portion that inhibits viewing of the composition within the container.

Disclosed herein are propellants comprising fluorocarbons and/or hydrofluorocarbons. Also disclosed are sprayable compositions comprising the propellants.

Substrates, and personal-care appliances made from such substrates, include an inter-bonded fibrous layer having shaped discontinuities and reinforcing strands attached to said inter-bonded fibrous layer. Pores between the fibers in the inter-bonded fibrous layer are suited to help hold liquid. The shaped discontinuities are suited to help generate suds or lather should the substrate or personal-care appliance be used in combination with a cleaning composition, soap formulation, or other such material having a surface-active agent or other chemical or compound that helps generate lather. The reinforcing strands help strengthen, or improve the wet resilience of, the inter-bonded fibrous layer. Furthermore, by selecting the appropriate ingredients of the reinforcing strands, the strands may be stiffer than the inter-bonded fibrous layer, thereby helping to provide some exfoliating character to the substrate or personal-care appliance.

Disclosed is a two-side personal-care appliance for various applications, including exfoliation of skin. The appliance comprises a first interbonded fibrous layer having three-dimensional contours on both faces of the layer. These contours facilitate exfoliation and/or stimulation and/or gentle abrasion of skin. Furthermore, these contours facilitate contact and attachment to the second interbonded fibrous layer. The second interbonded fibrous layer comprises a high-loft material capable of gently cleaning skin, holding liquid, and generating lather.

Disclosed is a skin-protecting alkalinity-controlling composition comprising an alkylene oxide derivative of pectin having a degree of esterification in the range from about 30% to about 100%.

Described are polyester compositions comprising (a) a dicarboxylicacidcomponent comprising terephthalic acid residues; optionally, aromatic dicarboxylic acid or aliphatic dicarboxylic acid residues; minimal amounts of 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; ethylene glycol, and optionally, cyclohexanedimethanol residues.

The present invention provides therapeutically effective 2,4,5-trisubstituted imidazole compounds, methods of preparing the same, and compositions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-microbial agents. The anti-microbial properties of the compounds include anti-bacterial and/or anti-fungal activity.

Disclosed are fluid dispensers comprising: a) a fluid reservoir, b) a fluid feed line, c) a fluid transfer zone, d) a capillary overflow, e) a capillary control valve, and f) a porous applicator head, wherein: i) the fluid feed line communicates with the fluid reservoir and the fluid transfer zone; ii) the fluid transfer zone is intermediate to the porous applicator head and capillary overflow; iii) the capillary overflow is in communication with the transfer zone and/or the fluid feed line; and iv) fluid is drawn through the porous applicator head by means of capillary action; and v) the capillary control valve regulates the flow of fluid in and out of the capillary overflow.

A viscoelastic composition containing an effective amount of at least one cationic carbohydrate ether having one or more cationic fragments and one or more carbohydrate fragments connected through one or more linker fragments for controlling the viscoelasticity of the composition, wherein at least some carbohydrate fragments are connected to the linker fragments through ether bonds.

A personal cleansing composition in solid or bar form which is mild to the skin and very effective in removing dirt and grime from the body, particularly the hands. Importantly, such soap bars do not have a noticeable abrasive feel when in contact with the skin. Another feature is that the bar exhibits a so called "drag effect" when the soap bar is used for washing.

A personal care composition and multi-phase personal care composition are described that comprise 3% or less, by weight of the personal care composition, of a perfume. The personal care composition comprises at least 0.27%, by weight of the personal care composition, of the perfume raw materials having a Kovat's Index of greater than 1700.

A process was developed for expressing antimicrobial peptides in a recombinant host cell that eliminates host cell toxicity and antimicrobial peptide degradation, as well as providing a process for rapid purification. Fusion proteins comprising a periplasmic targeting signal, cleavage site, and antimicrobial peptides provide the basis for this process which produces antimicrobial peptides that may be used in antimicrobial compositions and articles.

Compositions comprising microcrystalline cellulose, cellulose ether, and salt are provided together with methods for making them. Additionally, there are also described edible food products and industrial suspensions formed from these compositions.

An absorbent article comprises a backsheet and an absorbent layer, where the absorbent layer comprises a flexible superabsorbent binder polymer composition positioned adjacent to the backsheet. The absorbent layer may additionally include a substrate, and the article may additionally include a topsheet. The flexible superabsorbent binder polymer composition may be made from the reaction product of a monomer solution including at least 15% by weight monoethylenically unsaturated monomer, an acrylate or methacrylate ester that contains an alkoxysilane functionality, a copolymerizable hydrophilic glycol containing an ester monomer, an initiator system, and a neutralizing agent. The result is an absorbent article which exhibits improved performance as well as greater comfort and confidence among the user.

Compositions comprising a powder and an alkyl-phenyl silsesquioxane resin are disclosed. These compositions are particularly useful in a variety of personal or medical care compositions to enhance the durability and substantivity of powders after topical application.

Personal care composition comprising from about 5% to about 75% of an oil phase; an aqueous phase; from about 0.1% to about 2% of a polymeric thickener; and a skin care active; wherein said composition comprises at least two separate phases, and after agitation and dispensation from a suitable container containing a suitable propellant, forms stable foam.

Compositions comprising disiloxane surfactant compositions comprising a silicone composition comprising a silicone having the formula: MM'where M=R.sup.1R.sup.2R.sup.3SiO.sub.1/2;M'=R.sup.4R.sup.5R.sup.6SiO.sub.1/2;wi- th R.sup.1 selected from the group consisting of branched monovalent hydrocarbon radical of from 3 to 6 carbon atoms and R.sup.7, where R.sup.7 has the formula: R.sup.8R.sup.9R.sup.10SiR.sup.l2with R.sup.8, R.sup.9, and R.sup.10 each independently selected from the group of monovalent hydrocarbon radicals having from 1 to 6 carbon atoms and monovalent aryl or alkaryl hydrocarbon radicals having from 6 to 13 carbon atoms and R.sup.12 is a divalent hydrocarbon radical having from 1 to 3 carbon atoms, R.sup.2 and R.sup.3 are each independently selected from the group of from 1 to 6 carbon atom monovalent hydrocarbon radicals or R.sup.1, with R.sup.4 an alkylpolyalkyleneoxide of the general formula: R.sup.13(C.sub.2H.sub.4O).sub.a(C.sub.3H.sub.6O).sub.b(C.sub.4H.sub.8O).s- ub.cR.sup.l4where R.sup.13 is a divalent linear or branched hydrocarbon radical having the structure: --CH.sub.2--CH(R.sup.15)(R.sup.16).sub.dO--where R.sup.15 is H or methyl; R.sup.16 is a divalent alkyl radical of 1 to 6 carbons where the subscript d may be 0 or 1; R.sup.14 is selected from the group consisting of H, monovalent hydrocarbon radicals of from 1 to 6 carbon atoms and acetyl where the subscripts a; b and c are zero or positive and satisfy the following relationships: 2.ltoreq.a+b+c.ltoreq.20 with a.gtoreq.2,and R.sup.5 and R.sup.6 are each independently selected from the group of monovalent hydrocarbon radicals having from 1 to 6 carbon atoms or R.sup.4 that exhibit resistance to hydrolysis over a wide pH range.

A method of stabilizing a multiphase composition is described. The composition rises a structured surfactant phase, a benefit phase and a perfume comprising perfume materials. The method comprises a step of selecting at least 70% of the perfume raw rials that have a ClogP of greater than 1.8.

A therapeutic article includes a skin contact layer having a plurality of fibers forming a plurality of point-bearing surfaces configured for wear against a user's skin; a personal care composition disposed proximate the fibers; an external layer attached to the skin contact layer; and an intermediate layer interposed between the skin contact layer and the external layer, the intermediate layer being configured to activate the personal care composition, the external layer being configured to direct the activated personal care composition through the skin contact layer to treat the user.

A shaving kit comprising a personal care article is disclosed. The shaving kit comprises a package containing a personal care composition comprising a surfactant, water and at least about 15% of a hydrophobic moisturizing material and a plurality of razor blade cartridges or a shaving razor. An article of commerce is also disclosed that comprises a personal care article comprising a package containing a visually distinct, multiphase personal care composition and a set of in association with the personal care article. A method of shaving is also disclosed. The method comprises the steps of: wetting a skin surface; dispensing the multiphase personal care composition from the personal care article that comprises a package containing a visually distinct, multiphase personal care composition; contacting a skin surface with the personal care composition, and applying a shaving razor to the skin surface.

Compositions for cleaning and/or polishing are provided. The compositions comprise a first abrasive, a film comprising a second abrasive, and a carrier. The carrier can be in the form of an oral care composition, a personal care composition, a household care composition, and the like. The present invention also provides methods of cleaning and/or polishing a target surface.

A multi-phase personal cleansing composition comprising: (a) a structured aqueous cleansing phase comprising a surfactant and water; and (b) at least one additional, non-lamellar aqueous phase; wherein at least one of said structured aqueous cleansing phase and said additional aqueous phase comprises at least one non-migrating colorant, said non-migrating colorant comprising a cLogP value of at least about 2; and wherein said structured aqueous cleansing phase and said additional aqueous phase are packaged in physical contact with one another.

An elastic material that lowers extension tension over a given range without a significant impact on the retractive tension or stress relaxation. The elastic laminate includes a first set of elastic members attached to one or more substrates while the elastic members are stretched, and a second set of elastic members or an elastic film attached to the one or more substrates while the elastic members or film are stretched to a different extent than the first set of elastic members. Both the substrate(s) and one of the sets of elastic members or film are gathered when the other set of elastic members or film is relaxed. Also included is a method of making the differentially-stretched elastic laminate.

A composition and an article comprising or produced from the composition are disclosed. The composition comprises an ionomer and a reducing static charge-buildup amount of potassium ion wherein the ionomer is neutralized with sodium, zinc, or magnesium ions. The article can be a film including a multilayer film.

A polyolefin-based elastic hot melt adhesive composition having oil resistance, creep resistance and excellent bond strength is provided. The adhesive composition is useful in elastic laminates used in personal care absorbent articles and other garments.

An absorbent article comprises a backsheet and an absorbent layer, where the absorbent layer comprises a support substrate and a superabsorbent polymer composition positioned adjacent to the substrate. The absorbent layer may also include an additional substrate, and the article may additionally include a topsheet. The superabsorbent polymer composition comprises a water-soluble ionic polymer capable of sufficient non-radiative crosslinking within about 10 minutes at a temperature of about 120.degree. C. or less to reach an absorbent capacity of at least 1 g/g as measured by the Centrifuge Retention Capacity Test. In addition, the absorbent layer is restretched. The result is an absorbent article which exhibits improved performance as well as greater comfort and confidence among the user.

Microfluidic devices that comprise upstream channels that have a resistance higher than the resistance of the down stream channels are robust for blending two fluids, especially if they are oil and water or of different viscosities.

Methods to treat, prevent, and modulate aging of the skin are provided. More particularly, methods are provided for treating or preventing non-light induced skin aging in an organism and for reducing the basal MMP-10 expression in unirradiated cells of an organism and/or reducing the basal MMP-1 RNA transcription and protein translation in unirradiated cells of an organism, which include administering an effective amount of .beta.-carotene, a precursor of .beta.-carotene, a derivative of .beta.-carotene, a salt of .beta.-carotene, or a combination thereof to an organism in need thereof. Also provided are compositions for treating and preventing non-light induced aging of the skin. In addition, methods for modulating UV-A induced RNA transcription and polypeptide translation of a matrix metalloprotease (MMP) and treating or ameliorating UVA-induced photoaging by administering to an organism in need thereof an effective amount of a composition comprising .beta.-carotene, a precursor of .beta.-carotene, a derivative of .beta.-carotene, a salt of .beta.-carotene, or a combination thereof are provided. Compositions for modulating the effect of UVA-induced RNA transcription and polypeptide translation of a matrix metalloprotease (MMP) are also provided.

Microencapsulated delivery vehicles comprising an active agent are disclosed. In one embodiment, the microencapsulated delivery vehicles are heat delivery vehicles capable of generating heat upon activation. The microencapsulated heat delivery vehicles may be introduced into wet wipes such that, upon activation, the wet wipe solution is warmed resulting in a warm sensation on a user's skin. Any number of other active ingredients, such as cooling agents and biocides, can also be incorporated into a microencapsulated delivery vehicle.

A hybrid absorbent foam includes an integrated hybrid foam layer having an open surface, a closed surface, and a foam body extending between the open and closed surfaces. The integrated hybrid foam layer has an open-cell content of at least 50%, while the closed surface provides a barrier to aqueous liquids. The integrated hybrid foam layer is formed as a single layer, and has a substantially uniform polymer composition throughout its thickness. The integrated hybrid foam layer combines the functions of liquid absorbency, retention, and barrier into a single layer, and is useful in a wide variety of absorbent articles.

Microencapsulated delivery vehicles comprising an active agent are disclosed. In one embodiment, the microencapsulated delivery vehicles are heat delivery vehicles capable of generating heat upon activation. The microencapsulated heat delivery vehicles may be introduced into wet wipes such that, upon activation, the wet wipe solution is warmed resulting in a warm sensation on a user's skin. Any number of other active ingredients, such as cooling agents and biocides, can also be incorporated into a microencapsulated delivery vehicle.

The invention relates to a core shell capsule containing in the core an oil or waxy solid, wherein the oil or waxy solid comprises: (1) 50-100% by weight of a perfume composition, which is a mixture of at least two perfume ingredients-selected from: a) aldehydes, including alpha beta unsaturated aldehydes, which constitute 0-20% by weight of the perfume composition; b) primary or secondary amines constituting 0-10% by weight of the perfume composition; c) perfume ingredients having ClogP>4.0, which constitute 0-25% by weight of the perfume composition; d) perfume ingredients having ClogP>5.0, which constitute 0-20% by weight of the perfume composition; and e) perfume ingredients having ClogP<2.0, which constitute 0-20% by weight of the perfume composition, and (2) 0-50% by weight of benefit agents other than perfume ingredients.

A silsesquioxane resin wax composition, method for its preparation, and use in personal, household, automotive and medical care compositions are disclosed. The silsesquioxane resin wax can also find utility in a variety of oil and gas field applications, such as for crude oil wax control.

The present disclosure presents materials comprising hydrogenated and/or partially hydrogenated polymerized vegetable oils. Non-limiting applications of the polymerized oils, including coatings, binders, blends, and greases are presented. Methods for forming these materials are also disclosed.

A flexible package has a top surface, a bottom surface and at least one side wall together defining an interior volume of the package. An opening device is attached to the top surface and is at least in part detachable from the top surface to provide access to the interior volume. An article is secured to the opening device for conjoint movement with the opening device upon detachment of the opening device from the top surface of the package. In another embodiment, a portion of the side wall extends outward beyond the top surface to a free edge. A closure system is operable on the extended portion of the side wall to permit selective closing and opening of the package.

The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films contain a topical active agent.

A multi-phase personal cleansing composition is described that comprises a first visually distinct phase including a structured surfactant component and a second visually distinct phase comprising a benefit phase comprising an emulsion. The structured surfactant component comprises at least one branched anionic surfactant and from 0 to 10 % by weight of the first visually distinct phase, of sodium trideceth sulfate.

This invention relates to polyolefin compositions. In particular, the invention pertains to elastic polymer compositions that can be more easily processed on cast film lines, extrusion lamination or coating lines. The compositions of the present invention preferably comprise an elastomeric polyolefin resin and a high pressure low density type resin.

Personal care compositions comprise (a) from about 0.01 wt. % to about 10 wt. % of a water-soluble cationically modified starch polymer, wherein said water-soluble cationically modified starch polymer has a molecular weight from about 250,000 to about 15,000,000 and a charge density from about 0.2 meq/g to about 5 meq/g; (b) from about 5 wt. % to about 50 wt. % of an anionic surfactant system, said anionic surfactant system comprising at least one anionic surfactant and having an ethoxylate level and an anion level, (i) wherein said ethoxylate level is from about 1 to about 6, and (ii) wherein said anion level is from about 1 to about 6; and (c) a cosmetically acceptable medium. Personal care compositions as described above further comprise from about 0.01 wt. % to about 10 wt. % of one or more oily conditioning agents. Methods of treating hair or skin comprise applying the personal care compositions as described above to the hair or skin and rinsing the hair or skin.

A solid composition comprising oil core aphrons dispersed in a solid surfactant.

The present invention relates to highly compatible hydroxyphenyltriazine UV-absorbers and to their use in protecting plants in green houses and the protection of foodstuffs, beverages, pharmaceuticals, cosmetics, personal care products, shampoos and the like from the deleterious effects of ultraviolet radiation. It has been found that certain highly compatible tris-aryl-s-triazines are especially effective towards this end when incorporated in the containers or films in which such materials are stored.

A container for liquid compositions including a reservoir including a liquid composition a surface topography and an in-mold label positioned proximate to the surface topography to improve the resilience of the container. The surface topography is selected from the group consisting of ridges, valleys, grooves, dimples, depressions, bumps, convexity, concavity, ribs, protrusions, curves, raised surfaces or other surface topography. The in-mold label has a thickness of at least 4.5 mils; wherein the in-mold label is made from a material selected selected from the group consisting of polyethylene, copolymers of polyethylene, polypropylene, copolymers of polypropylene, nylon, polyester, copolymers of polyester, polylactic acid, cellophane, polyvinyl chloride, ionomers, ethylene-acrylic acid copolymers, metallocene polyethylene, metallocene polypropylene, and mixtures thereof.

Siloxane resin compositions obtained by mixing a MQ siloxane resin with a propyl silsesquioxane resin are disclosed. These siloxane resins are useful in a variety of personal, household, automotive and medical care applications, and in particular, as a resin additive in pigmented cosmetic formulations.

Multiphase personal care compositions that can deliver one or more benefits in a single product. The multiphase personal care compositions can provide multiple benefit effects through the inclusion of beads. The beads are stable and maintain their arrangement within the composition, withstanding the conditions reasonably expected during shipment, storage, and use. The compositions comprise a plurality of visually distinct phases wherein one of the phases comprises one or more beads, where the beads are individually visually distinct and visible within the composition. Further, the phases are arranged in a non-random pattern. A method for making the multiphase personal care compositions is also disclosed.

An active or functional organic compound is solubilized by an ester of an aryl alcohol, e.g., phenethyl, benzyl or substituted benzyl alcohol, and an alkyl or cycloalkyl carboxylic acid, or by a carbonate of said aryl alcohol and an alkyl or cycloalkyl carbonic acid.

The present invention relates to the use of a mixture of modified starch and protein for encapsulating oxygen sensitive agents, wherein the modified starch is a starch derivative containing a hydrophobic group or both a hydrophobic and a hydrophilic group which has been further enzymatically hydrolyzed by an exo-enzyme. The encapsulated materials have a high level of active agent and retention and provide excellent oxidation resistance. Further, the encapsulated materials are useful in a variety of products, including food products.

Processes for altering surface properties of pigment particles are provided. The processes include coating the particles with ionic natural polysaccharides or ionic derivatives of natural polysaccharides, providing enhanced properties.

Personal care compositions comprising a PPARG antagonist, use of such compositions, and methods of marketing such compositions. The personal care compositions can be applied topically, ingested orally, injected, or used as part of a regimen.

Personal care compositions comprising skin and/or hair care actives. Such compositions are useful for regulating the condition of mammalian keratinous tissue needing such treatments, particularly skin lightening. In accordance with one embodiment, there is provided a personal care composition comprising a safe and effective amount of a first active selected from the group consisting of erythritol, p-cymen-7-ol, benzyl phenylacetate, 4-(4-methoxyphenyl)butan-2-one, ethoxyquin, tannic acid, gallic acid, octadecenedioic acid, p-cymen-5-ol, methyl sulfonyl methane, an avenathramide compound, and combinations thereof.

Water-soluble functionalized cationic copolymers obtainable by a process which comprises reacting a cationic base polymer which contains amino groups with at least one functional compound reactive to at least a part of the amino groups on the base polymer, are useful in personal care and cosmetic formulations.

A clamshell package is provided for holding and displaying a consumer product that comprises a bottle and a cap. The clamshell package comprises a first clamshell side and a second clamshell side, wherein at least a portion of the first and second clamshell sides are affixed together to hold the consumer product between the first and second clamshell sides. The clamshell package further comprises an aperture through which at least a portion of the cap of the consumer product extends from the clamshell package. The clamshell package is therefore able to hold and display the consumer product, while allowing a consumer to access the cap of the product in order to smell or to sample the product. A clamshell package is further provided for holding and displaying a consumer product comprising liquid composition contained in a tottle.

Propellants comprising a combination of: (a) a liquid component that is soluble in the organic chemical-based material; (b) a soluble gas component that has a solubility of at least about 3% by weight in the organic chemical-based material; and, (c) a substantially insoluble gas component that has a solubility of less than about 3% by weight of the organic chemical-based material are effective for a wide range of airless applications. Adjustment of the ratios of (a) to (b) to (c) can lead to propellants that provide excellent spray patterns for a wide range of organic chemical-based formulations.

Personal care composition comprising a dehydroacetate salt, and a dermatologically acceptable carrier, wherein the pH of said composition is about 7.0 and greater.