Title: Methods of Transdermally Administering an Indole Serotonin Receptor Agonist and Transdermal Compositions for Use in the Same

Applicant/Assignee:

Application No.: 12/877848   Filing Date: 08/Sep/2010

Abstract:

Methods of transdermally delivering a therapeutic amount of an indole serotonin receptor agonist to an individual in need thereof, e.g., to provide a therapeutic level of an indole serotonin receptor agonist to an individual in need thereof, are provided. Also provided are transdermal formulations of indole serotonin receptor agonists that find use in practicing the subject methods.

Priority: US2006-561235 Applic. Date: 2006-11-17; US20050752767P Applic. Date: 2005-12-20; US20060790451P Applic. Date: 2006-04-06

Inventor: YONETO KUNIO [US]; INOO KATSUYUKI [JP]

Title: Microvesicles

Applicant/Assignee: LYDAC NEUROSCIENCE LIMITED

Application No.: 12/811113   Filing Date: 02/Jan/2009

Abstract:

A method of producing a population of differentiated cells comprising: a) inducing differentiation in a first population of cells by applying an inducer to said cells, b) harvesting microvesicles produced from first population of cells, and c) inducing differentiation in a second population of cells by applying said microvesicles or a derivative thereof to said second population of cells wherein, said first population of cells is autologous to said second population of cells and wherein the inducer applied to said first population of cells is not present in said second population of cells or is only present in trace amounts. Also related methods of producing microvesicles, methods of medical and/or cosmetic treatment and related products and uses.

Priority: GB20080000107 Applic. Date: 2008-01-04; GB20080004932 Applic. Date: 2008-03-17; WO2009GB00004 Applic. Date: 2009-01-02

Inventor: RAY STEPHEN [GB]

Title: External Composition for Skin

Applicant/Assignee: ROHTO PHARMACEUTICAL CO., LTD

Application No.: 12/935497   Filing Date: 26/Mar/2009

Abstract:

An external composition for skin is provided, which gives good warmth without inducing irritation or pain and whose sustainability of warmth is good. The external composition for skin contains (A) an agent for giving warmth and (B) at least one member selected from the group consisting of fatty acid esters of aliphatic polyhydric alcohols and aromatic carboxylic acid esters of lower alcohols or aliphatic polyhydric alcohols.

Priority: JP20080090895 Applic. Date: 2008-03-31; WO2009JP56081 Applic. Date: 2009-03-26

Inventor: HIRAYAMA YOSHIYUKI [JP]

Title: COMPOSITION AND METHOD INHIBITING INFLAMMATION

Applicant/Assignee:

Application No.: 12/675504   Filing Date: 26/Feb/2010

Abstract:

Composition and method for preventing, treating or attenuating inflammatory diseases by way of inhibiting lipid peroxidation and subsequent elementary inflammation through ensuring the presence of the following biologically active ingredients in the PMRS of cells involved in inflammation: i) at least one killed probiotic and ii) at least one omega 3 FA and iii) vitamin E and iv) ubiquinone by introducing a composition comprising any of the missing ingredients.

Priority: HU20070000552 Applic. Date: 2007-08-27; WO2008HU00098 Applic. Date: 2008-08-27

Inventor: FEHER JANOS [HU]

Title: Cosmetic or dermatological article comprising a medium that is soluble in water

Applicant/Assignee: L'OREAL

Application No.: 12/805327   Filing Date: 26/Jul/2010

Abstract:

The present invention relates to a cosmetic or dermatological article comprising: a medium in the form of at least one sheet of a material that is soluble in water at a temperature lower than 20 DEG C.

and at least one cosmetic or dermatological compound carried by the medium.

Priority: FR20050050014 Applic. Date: 2005-01-03; US2005-303961 Applic. Date: 2005-12-19; US20050658165P Applic. Date: 2005-03-04

Inventor: SIMON PASCAL [FR]

Title: Gel Product

Applicant/Assignee: SILIPOS INC

Application No.: 12/857944   Filing Date: 17/Aug/2010

Abstract:

A gel construct includes a viscoelastic gel pad with migratory oils or also synthetic or triglyceride fluids, emollients, waxes, vitamins, humectants, pharmaceutical actives, and other hair or skin conditioning or treatment agents. The gel construct also includes a body, hair or skin-side layer on one major side surface of the gel pad which is permeable to the migratory agents of the gel. The gel construct optionally includes a barrier layer on the opposite major side surface of the gel pad to prevent the migratory agents of the gel from penetrating that layer. The gel construct may find use as, for example, an insole.

Priority: US20090234520P Applic. Date: 2009-08-17

Inventor: MATTELIANO CHARLES J [US]; MAY BARRY A [US]

Title: FOAM CONTAINING BENZOYL PEROXIDE

Applicant/Assignee: FOAMIX LTD

Application No.: 12/745417   Filing Date: 01/Dec/2008

Abstract:

The present invention relates to foamable compositions for treating acne comprising benzoyl peroxide

to a therapeutic kit comprising such compositions

and to a method of treating acne using such compositions.

Priority: US20070004838P Applic. Date: 2007-11-30; WO2008IB03908 Applic. Date: 2008-12-01

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; SCHUZ DAVID [IL]; KEYNAN RITA [IL]; BERMAN TAL [IL]; DANZIGER JORGE [IL]

Title: COMPOSITIONS AND METHODS FOR THE DELIVERY OF AGENTS

Applicant/Assignee:

Application No.: 12/933337   Filing Date: 26/Mar/2009

Abstract:

The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

Priority: US20080040016P Applic. Date: 2008-03-27; WO2009US01910 Applic. Date: 2009-03-26

Inventor: GOLUBOVIC-LIAKOPOULOS NEVENKA [US]; SHAH BHAVDEEP [US]; ANDERSEN ERIK [DK]

Title: Use of Deuterium Oxide as an Elastase Inhibitor

Applicant/Assignee:

Application No.: 12/988694   Filing Date: 16/Apr/2009

Abstract:

The invention relates to the use of deuterium oxide (D2O) as an elastase inhibitor and especially as an inhibitor of the human neutrophil elastase (HNE). The invention also relates to the use of deuterium oxide for the prophylaxis and/or treatment of HNE-related diseases.

Priority: EP20080007676 Applic. Date: 2008-04-20; WO2009IB05999 Applic. Date: 2009-04-16

Inventor: BAYERL THOMAS [GB]

Title: CONTROLLED RELEASE OF ACTIVE AGENTS FROM OLEOSOMES

Applicant/Assignee: SEMBIOSYS GENETICS, INC

Application No.: 12/935069   Filing Date: 10/Apr/2009

Abstract:

The release rate of an active agent from oleosomes can be modulated by formulation of the oleosomes with a release control agent, such as a multihydric alcohol. In this context, oleosomes containing an active agent may be used in the preparation of a variety of formulations, including formulations for topical use.

Priority: US20080071109P Applic. Date: 2008-04-11; WO2009US02242 Applic. Date: 2009-04-10

Inventor: GUTH JACOB [US]; FERGUSON JOHN [US]

Title: FLUIDIC TISSUE AUGMENTATION COMPOSITIONS AND METHODS

Applicant/Assignee:

Application No.: 12/776325   Filing Date: 07/May/2010

Abstract:

Compositions and method for augmenting tissue after delivery to localized area. The compositions include a hydrogel and a dermal filler. The hydrogel can polymerize and/or crosslink upon a first trigger event. The dermal filler can also optionally crosslink upon a second trigger event.

Priority: US2007-685094 Applic. Date: 2007-03-12; US2006-276759 Applic. Date: 2006-03-13

Inventor: DAVID NATHANIEL E [US]; ELISSEEFF JENNIFER [US]

Title: Particulate Detergent Additive

Applicant/Assignee:

Application No.: 12/983344   Filing Date: 03/Jan/2011

Abstract:

Laundry-detergent and cleaning-product additives in particle form, comprising a water-soluble or water-dispersible carrier and active ingredient microcapsules. These particles allow a user to obtain particular advantages with respect to fragrancing and care of the articles treated in conventional laundering and cleaning operations, such as, in particular, in automatic laundering of fabrics.

Priority: DE200810031212 Applic. Date: 2008-07-03; WO2009EP56906 Applic. Date: 2009-06-05

Inventor: SUNDER MATTHIAS [DE]; STURM MARIO [DE]; SEGLER TOBIAS [DE]; WRUBBEL NOELLE [DE]

Title: Personal Care Compositions Having Improved Compatibility and Providing Improved Sun Protection

Applicant/Assignee: DOW CORNING CORPORATION

Application No.: 12/993867   Filing Date: 06/Jul/2009

Abstract:

Personal care composition having improved compatibility and providing improved sun protection are obtained by including a liquid silicone resin having greater than 50 mole percent Me3SiO1/2 and PrSiC3/2 units, where Me is methyl and Pr is propyl in the composition. If desired to enable additional compatibility of ingredients comprising the personal care composition, the liquid silicone resin can also contain PhSiO3/2 or Ph2SiO2/2 units, where Ph is phenyl, or a mixture thereof.

Priority: US20080084635P Applic. Date: 2008-07-30; WO2009US49662 Applic. Date: 2009-07-06

Inventor: HORSTMAN JOHN BERNARD [US]; KING DOUGLAS W [US]; PRETZER PAUL W [US]; SCHMIDT RANDALL [US]; WIEBER GARY [US]; LEAYM TINA [US]; PRETZER MARIA R [US]

Title: Zinc Salt Compositions for the Prevention of Dermal and Mucosal Irritation

Applicant/Assignee:

Application No.: 12/972036   Filing Date: 17/Dec/2010

Abstract:

The present invention provides for compositions and methods that may offer protection from irritants as well as antimicrobial protection. Preferred embodiments of the invention include topical antimicrobial compositions that lack conventional antibiotics or preservatives, wherein the antimicrobial benefit is created by essential oils (or their active ingredients), emollient solvents and, in some instances, anti-inflammatory agents.

Priority: US2004-892034 Applic. Date: 2004-07-15; US2003-622272 Applic. Date: 2003-07-17; WO2003US03896 Applic. Date: 2003-02-07; US20020355549P Applic. Date: 2002-02-07

Inventor: MODAK SHANTA M [US]; GAONKAR TRUPTI [US]; SHINTRE MILIND [US]; CARAOS LAUSERPINA [US]

Title: TOPICAL COMPOSITIONS AND METHODS FOR EPITHELIAL-RELATED CONDITIONS

Applicant/Assignee: SIGNUM BIOSCIENCES, INC

Application No.: 12/968800   Filing Date: 15/Dec/2010

Abstract:

The present invention relates to pharmaceutical, cosmetic and cosmeceutical topical compositions containing polyisoprenyl-protein inhibitor compounds and methods useful in the promotion of healthy epithelium and the treatment of epithelial-related conditions

Priority: US2005-151174 Applic. Date: 2005-06-13; US20050652921P Applic. Date: 2005-02-14; US20040579093P Applic. Date: 2004-06-12

Inventor: STOCK JEFFRY B [US]; GORDON JOEL [US]; STOCK MAXWELL [US]

Title: Block Copolymer and Ester-Terminated Polyesteramide Composition and Uses Thereof

Applicant/Assignee: AVON PRODUCTS, INC

Application No.: 12/645919   Filing Date: 23/Dec/2009

Abstract:

Compositions and methods for the preparation of a composition comprising a block copolymer and ester-terminated polyester amide solubilized in a compatible solvent are disclosed. The disclosed compositions are long-lasting, transfer resistant, flexible, and water-proof capable of complexing the active ingredient to provide such benefits. The disclosed compositions are useful for formulating cosmetics, personal care products, cosmeceuticals, and the like.

Priority:

Inventor: SHAH ARVIND N [US]; ROBINSON FREDA E [US]; CRUZ KATHY [US]; BINDER DAVID ALAN [US]; MAITRA PRITHWIRAJ [US]

Title: Transdermal Delivery of Apomorphine Using Microneedles

Applicant/Assignee:

Application No.: 13/060118   Filing Date: 21/Aug/2009

Abstract:

The present invention relates generally to methods for transdermal delivery of a therapeutically effective amount of apomorphine using microneedles. The invention also provides methods for treatment of erectile dysfunction and Parkinson's disease using apomorphine hydrochloride or any pharmaceutically acceptable salt, and/or apomorphine prodrugs to the microneedle-treated site.

Priority: US20080090989P Applic. Date: 2008-08-22; WO2009US54604 Applic. Date: 2009-08-21

Inventor: AL-GHANANEEM ABEER M [US]

Title: NETWORK COPOLYMER CROSSLINKED COMPOSITIONS AND PRODUCTS COMPRISING THE SAME

Applicant/Assignee: MOMENTIVE PERFORMANCE MATERIALS INC

Application No.: 12/975885   Filing Date: 22/Dec/2010

Abstract:

The present invention provides for a household, agricultural, coating or personal care product composition containing the crosslinked reaction product of a network composition the reaction product of: (i) at least one anionic polymerizable ethylenically unsaturated monomer (I) selected from the group consisting of [CH2-C(R3)C(O)OXa(C2H4O)b(C3H6O)c(C4H8O)d]pP(O)(OY)q(OZ)r where R3-H or alkyl of 1 to about 6 carbon atoms

X=alkyl, aryl, or alkaryl diradical connecting group of 0 to about 9 carbon atoms

a is 0 to about 100

b is 0 to about 100

c is 0 to about 100

d is 0 to about 100

q is 0 to about 2

r is 0 to about 2

p is 1 to about 3 subject to the limitation that p+q+r=3

and Y and Z is H, or metal ion

and CH2-C(R3)C(O)OXa'(C2H4O)b'(C3H6O)c'(C4H8O)d'-SO3-Y) where R3-H or alkyl of from 1 to about 6 carbon atoms

X=alkyl, aryl, or alkaryl diradical connecting group of 0 to about 9 carbon atoms

a' is 0 to about 100

b' is 0 to about 100

c' is 0 to about 100

d' is 0 to about 100

Y is H, or metal ion

and (ii) one or more additional monomers (II) selected from the group consisting of acrylic acid/acrylate, methacrylic acid/methacrylate, acrylamides, vinyl acetate and styrene, which are copolymerizable with (I)

and (iii) a cross-linking agent (III), capable of copolymerizing with (I) and (II).

Priority: US20090289782P Applic. Date: 2009-12-23

Inventor: LU NING [US]; GONZALEZ SIGFREDO [US]; SILVESTRE EMIE M [US]; WANG GENG [US]

Title: PERSONAL CARE PRODUCTS CONTAINING RAINWATER

Applicant/Assignee:

Application No.: 13/059578   Filing Date: 24/Aug/2009

Abstract:

This invention relates generally to formulations and methods for improving level of moisture absorption and retention by the skin and for improving the appearance, feel, or comfort of the skin, wherein the formulations comprise pure rainwater. In another embodiment of the invention, the formulations comprise a combination of natural extracts. The present invention is a formulation made substantially without the use of synthetic chemicals and petroleum by-products, wherein the formulation is used for personal care. More specifically, the present invention is a skin care product formulation wherein 90% or more of the ingredients are natural products.

Priority: US20080090969P Applic. Date: 2008-08-22; WO2009US54784 Applic. Date: 2009-08-24

Inventor: VILINSKY PNINA [US]

Title: PHASE-TRANSITION POLYMERIC MICRONEEDLES

Applicant/Assignee:

Application No.: 13/122873   Filing Date: 12/May/2009

Abstract:

This invention discloses a novel microneedle system, phase-transition microneedle patch, which overcomes all the limitations that existing microneedles encountered. The microneedle patch is formed of an integrated polymeric piece consisting of a microneedle array and a plate (called holding plate) on which the needles stand. The microneedles of the patch are hard and strong enough to penetrate epidermis at dry state but turn to be hydrogel state soft and permeable to hydrophilic agents when absorbing body fluid. The hydrogel state of the patch is a hydrophilic network held by physical or chemical cross-linking junctions. The pores of the network are opened up by body fluid for drugs and macromolecules to diffuse through. The polymeric materials used to form the microneedle patch have been used in the pharmaceutical field for years and have proven compatibility with the skin and with proteins. The drugs may be stored in the matrix of the microneedle array as well as the holding plate so that the requirement for high dose applications may be full filled. In addition, molding (casting) of this type of microneedle patch is simple, easy to achieve and needs no microfabrication systems and organic solvents. By a programmed molding (casting), the patch may be assembled in a layered structure with desired drug concentration in each layer, respectively. Due to this design, a programmed pulse or a zero order release of drugs may easily be achieved. In addition, delicate proteins loaded in the patch are kept in a dry and hydrophilic glassy state before being released, the most favored state for protein storage. Finally, during the swelling-based drug release, the microneedle patch increases their thickness gradually between the skin and the back cover (which holds the needles) lo create a sustained pressure to ensure good contact of the microneedles inside epidermis.

Priority: US20080103560P Applic. Date: 2008-10-07; WO2009CN00510 Applic. Date: 2009-05-12

Inventor: JIN TUO [CN]

Title: COMPOSITIONS FOR THE TREATMENT OF PAIN AND/OR INFLAMATION

Applicant/Assignee: BCN PEPTIDES, S.A, DIVERDRUGS, S.L

Application No.: 13/055598   Filing Date: 24/Jul/2009

Abstract:

Compositions for the treatment of pain and/or inflammation comprising at least one peptide with the general formula (I) R1-AA-R2, its stereoisomers, mixtures thereof, and its cosmetically and pharmaceutically acceptable salts. Peptide with general formula (I), its stereoisomers, mixtures thereof, and its cosmetically and pharmaceutically acceptable salts for the treatment of pain and/or inflammation.

Priority: ES20080002210 Applic. Date: 2008-07-24; WO2009EP05381 Applic. Date: 2009-07-24

Inventor: CARRENO SERRAIMA CRISTINA [ES]; VAN DEN NEST WIM [ES]; FERRER MONTIEL ANTONIO [ES]; CAMPRUBI ROBES MARIA [ES]; FERNANDEZ CARNEADO JIMENA [ES]; PONSATI OBLIOLS BERTA [ES]

Title: DERMAL DELIVERY

Applicant/Assignee: ANTERIOS, INC

Application No.: 13/000509   Filing Date: 26/Jun/2009

Abstract:

The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, and/or actinic keratosis. Methods generally involve administering nanoemulsions (e.g., nanoparticle compositions) comprising at least one therapeutic agent, such as botulinum toxin. In some embodiments, nanoemulsions are prepared, e.g., by high pressure microfluidization, and comprise a particle size distribution exclusively between 10 nm and 300 nm.

Priority: US20080076065P Applic. Date: 2008-06-26; WO2009US48972 Applic. Date: 2009-06-26

Inventor: EDELSON JONATHAN [US]; KOTYLA TIMOTHY [US]; ZHANG BOKE [US]

Title: Compositions and Methods for the Treatment of Skin Diseases and Disorders Using Antimicrobial Peptide Sequestering Compounds

Applicant/Assignee:

Application No.: 13/038524   Filing Date: 02/Mar/2011

Abstract:

The present invention provides compositions containing one or more antimicrobial peptide sequestering compounds and methods for topical application of such compositions to the skin to treat skin diseases and disorders such as rosacea in humans.

Priority: US20100310168P Applic. Date: 2010-03-03

Inventor: DREHER FRANK [US]

Title: EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES

Applicant/Assignee: L'OREAL

Application No.: 13/110486   Filing Date: 18/May/2011

Abstract:

The present invention relates to a composition in the form of an emulsion containing portions of hollow spheres of organosilicon-based material, the portions of hollow spheres having a mean diameter ranging from 0.05 to 10 [mu]m. The invention also relates to physiologically acceptable emulsion compositions comprising hollow spheres, and to a process for fading out skin surface defects, in particular to reduce the sheen of the skin and/or to fade out pores, shadows under the eyes, marks, wrinkles and/or fine lines, comprising the topical application to the skin of the above-mentioned compositions.

Priority: FR20030050829 Applic. Date: 2003-11-13; US2004-982925 Applic. Date: 2004-11-08; US20030529754P Applic. Date: 2003-12-17

Inventor: CASSIN GUILLAUME [FR]

Title: METHOD FOR SOLUBILIZING METRONIDAZOLE

Applicant/Assignee: GALDERMA S.A

Application No.: 13/110116   Filing Date: 18/May/2011

Abstract:

Metronidazole is solubilized in an aqueous phase, by mixing same with niacinamide and at least two glycolic cosolvents

the resulting solutions and pharmaceutical compositions comprised thereof are useful for the treatment of dermatological conditions/afflictions, notably rosacea.

Priority: FR20050006182 Applic. Date: 2005-06-17; US2007-000771 Applic. Date: 2007-12-17; WO2006FR01367 Applic. Date: 2006-06-16

Inventor: MALLARD CLAIRE [FR]; BRZOKEWICZ ALAIN [FR]

Title: COMPOSITIONS FOR THE PROPHYLAXIS AND TREATMENT OF DERMATOLOGICAL/MUCOSAL DISEASES, AND USES THEREOF

Applicant/Assignee:

Application No.: 12/737572   Filing Date: 28/Jul/2009

Abstract:

The present invention provides a composition containing a) clay material with a negative surface charge

b) magnesium ions and calcium ions both either incorporated within the clay material and/or added separately

c) water and/or non-aqueous solvent

d) substantially non-cationic carrier

where i) the mean particle size of the clay material is at least 5 nm

and ii) the total molar amount of magnesium ions is higher than the total molar amount of calcium ions. The present invention further relates to the use of said composition in the manufacture of a medicament for the prophylaxis and treatment of skin diseases, skin conditions, or mucosal diseases where the formation and/or recovery of epidermal/mucosal barrier function has beneficial effects.

Priority: EP20080462004 Applic. Date: 2008-07-28; WO2009EP59727 Applic. Date: 2009-07-28

Inventor: FELEKI ATTILA [HU]; MIGO THEODORUS A C [HU]

Title: TREATMENT OF PAIN WITH GAP JUNCTION MODULATION COMPOUNDS

Applicant/Assignee:

Application No.: 12/996359   Filing Date: 04/Jun/2009

Abstract:

The present invention relates to delivery, including transdermal delivery, of a therapeutically effective amount of a compound useful for modulating gap junction formation and function, including an oligonucleotide for reducing gap junction formation and function, and methods and compositions for treating a subject suffering from pain associated with a disease, disorder or condition and associated with pain, including but not limited to muscle pain, ligament pain, tendon pain, joint pain and post-operative pain.

Priority: US20080131127P Applic. Date: 2008-06-04; WO2009US03408 Applic. Date: 2009-06-04

Inventor: DUFT BRADFORD J [US]; GREEN COLIN RICHARD [NZ]

Title: STABILIZATION PROCESSES OF CATION RADICALS OF PHENOTHIAZINIC COMPOUNDS, COSMECEUTICAL FORMULATIONS AND METHODS FOR SKIN DISEASES AND DISTURBANCES PREVENTION

Applicant/Assignee:

Application No.: 12/992291   Filing Date: 12/May/2009

Abstract:

The present invention relates to processes of stabilization of cation radicals from one or more phenothiazinic compounds or derivatived compounds thereof. Another embodiment of the present invention relates to cosmeceutical formulations comprising one or more phenothiazinic compounds or derivatived compounds thereof, in combination with cosmeceutically acceptable excipients. The invention also relates to uses of one or more phenothiazinic compounds or derivatived compounds thereof, i the preparation of cosmeceutical formulations for the prevention of skin diseases and disturbances. Methods for prevention of skin diseases and disturbances are also disclosed by the present invention. Particularly, the embodiments of the present invention employ the cited one or more phenothiazinic compounds o derivatived compounds thereof in the form of their stabilized cation radicals.

Priority: BR2008PI01368 Applic. Date: 2008-05-12; WO2009BR00126 Applic. Date: 2009-05-12

Inventor: NANTES ISELI LOURENCO [BR]; RODRIGUES TIAGO [BR]; DOS SANTOS CAROLINA GREGORUTTI [BR]

Title: COMPOSITIONS FOR TOPICAL APPLICATION COMPRISING MICROENCAPSULATED COLORANTS

Applicant/Assignee: TAGRA BIOTECHNOLOGIES LTD

Application No.: 12/992446   Filing Date: 12/May/2009

Abstract:

Color-changing cosmetic or therapeutic compositions for topical application are provided, comprising one or more active substances and one or more microencapsulated colorants, which upon application on the skin provide a changing color effect that indicates the delivery of the active substances from said composition onto the skin and/or gives to the skin a visual esthetical effect.

Priority: US20080052411P Applic. Date: 2008-05-12; WO2009IL00478 Applic. Date: 2009-05-12

Inventor: KVITNITSKY EMMA [IL]; PALUY IRENA [IL]; OLEINIK IRENA [IL]; SADE TAL [IL]; YASMAN YURI [IL]

Title: COSMETIC FORMULATIONS COMPRISING POROUS SILICON

Applicant/Assignee:

Application No.: 13/121871   Filing Date: 30/Sep/2009

Abstract:

A cosmetic formulation comprising porous silicon is described.

Priority: GB20080017938 Applic. Date: 2008-09-30; WO2009GB51282 Applic. Date: 2009-09-30

Inventor: CANHAM LEIGH [GB]; MONGA TANYA [GB]

Title: METHOD OF TREATMENT OF DISEASES USING HOODIA EXTRACTS

Applicant/Assignee: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED, DESERT LABS AGRICULTURE COOPERATIVE ASSOCIATION LT

Application No.: 13/133255   Filing Date: 06/Dec/2009

Abstract:

A method for treating a disease comprising administering to a mammal in need thereof an effective dosage of an extract of a plant of the genus Hoodia, wherein the disease is selected from the group consisting of immune-mediated disorders, immune-associated disorders, inflammatory diseases, coronary disease, insulin resistance and liver-related diseases. In a preferred embodiment, the Hoodia is Hoodia parviflora. Also disclosed is a pharmaceutical composition for treating the above diseases comprising an effective dosage of an extract of a plant of the genus Hoodia.

Priority: US20080193571P Applic. Date: 2008-12-08; WO2009IL01152 Applic. Date: 2009-12-06

Inventor: AHARON REFAEL [IL]; ILAN YARON [IL]

Title: COLD PROCESS WATER SOLUBLE WAX CONTAINING POWDERS

Applicant/Assignee: JEEN INTERNATIONAL

Application No.: 12/832547   Filing Date: 08/Jul/2010

Abstract:

Inventive subject matter described herein includes a powder comprising: a wax having a melt point within a range of 45 to 100 degrees Centigrade and sodium polyacrylate or salts of sodium polyacrylate or sodium polyacrylate and salts of sodium polyacrylate wherein the wax concentration falls within a range of 99.9% to 0.1% by weight and the sodium polyacrylate concentration falls within a range of 0.1% to 99.9% by weight, wherein the powder is effective for forming a cream or lotion or gel or coating when mixed with water at room temperature or cooler than room temperature.

Priority: US20100347664P Applic. Date: 2010-05-24; US20100321765P Applic. Date: 2010-04-07

Inventor: MATEU JUAN R [US]; PERLE ADAM [US]

Title: PHARMACEUTICAL AND/OR COSMETIC COMPOSITION FOR TREATING THE SKIN

Applicant/Assignee: BIOFRONTERA BIOSCIENCE GMBH

Application No.: 13/081737   Filing Date: 07/Apr/2011

Abstract:

The present invention concerns the pharmaceutical and cosmetic application of biocolloids, which originate from the mixture of a nanoemulsion and at least one water-soluble plant extract such as an extract from Mahonia aquifolium, wherein the biological effect of the plant ingredients is enhanced by the composition although the nanoemulsion does not function as a carrier system. The biocolloids are especially for the treatment and care of the skin.

Priority: DE201020004750U Applic. Date: 2010-04-09; US20100322524P Applic. Date: 2010-04-09

Inventor: LUEBBERT HERMANN [DE]; ROCA MONTSERRAT FOGUET [DE]; GWAREK MIRELLA [DE]

Title: Method of treating and preventing breast diseases and breast cancer with medicated formula

Applicant/Assignee:

Application No.: 12/798723   Filing Date: 12/Apr/2010

Abstract:

Breast cancer is a common cancer in women. Early diagnosis and treatments are vital for better outcomes. This formula consists of a liquid anti-disease anti-cancer formula that can be delivered to the source where breast cancer begins. Method of treating breast disease, including cancer, with a formula and a means of delivery with a topical, intraductal, ductal, and/or intraductal infusion to prevent the formation of cancer or precursors to cancer or atypia or other form of abnormal breast tissue or to treat breast diseases of all kinds. May include homeopathic remedies to be used topically or inside the breast with a delivery method to those regions and may be processed with or without photonic programming or an ionic delivery system for greater effectiveness and use against degenerative diseases or cancerous or precancerous diseases, precursors of breast disease, inflammatory breast disease, or accumulation of toxins in the breast tissue.

Priority:

Inventor: BUCKMAN KEVIN [US]

Title: TOPICAL COMPOSITIONS CONTAINING COATED ACTIVE AGENTS

Applicant/Assignee: SOL-GEL TECHNOLOGIES LTD

Application No.: 13/126288   Filing Date: 05/Jan/2010

Abstract:

Provided is a multi component topical system including at least one component including at least one first active agent coated by metal oxide

and at least one skin treating component free of the active agent. Further provided are methods of using the multi component topical system and kits including them.

Priority: US20090193892P Applic. Date: 2009-01-05; WO2010IL00010 Applic. Date: 2010-01-05

Inventor: TOLEDANO OFER [IL]; MAVOR DANIELA [IL]; DRORI ELI [IL]; ERLICH MAYA [IL]; HERSHKOVITCH SHARON [IL]

Title: Pigmented Emulsion Makeup Compositions With Gemstones

Applicant/Assignee:

Application No.: 12/937134   Filing Date: 17/Feb/2009

Abstract:

A pigmented emulsion composition comprising a water phase, an oil phase, and a plurality of gemstones in particulate form, and a method for providing a glow to the skin and ameliorating the appearance of wrinkles, lines, and skin discoloration by applying a pigmented emulsion composition comprising a plurality of gemstones.

Priority: US20080047462P Applic. Date: 2008-04-24; WO2009US34245 Applic. Date: 2009-02-17

Inventor: DABE MICHELLE L [US]; MU WEILIN [US]; STEPNIEWSKI GEORGE J [US]

Title: DERMATOLOGICAL/COSMETIC GELS COMPRISING AT LEAST ONE RETINOID AND/OR RETINOID SALT AND BENZOYL PEROXIDE

Applicant/Assignee: GALDERMA RESEARCH & DEVELOPMENT

Application No.: 13/103613   Filing Date: 09/May/2011

Abstract:

Dermatological/cosmetic gel compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including preventing or treating common acne, comprise (i) at least one retinoid, (ii) dispersed benzoyl peroxide and (iii) at least one pH-independent gelling agent, formulated into (iv) a physiologically acceptable medium therefor.

Priority: FR20010016747 Applic. Date: 2001-12-21; US2008-076859 Applic. Date: 2008-03-24; US2002-326389 Applic. Date: 2002-12-23; US20020351382P Applic. Date: 2002-01-28

Inventor: ORSONI SANDRINE [FR]; WILLCOX NATHALIE [FR]

Title: DEPIGMENTING TOPICAL COMPOSITIONS AND THEIR USES

Applicant/Assignee: GALDERMA RESEARCH & DEVELOPMENT

Application No.: 13/126215   Filing Date: 28/Oct/2009

Abstract:

Depigmenting topical compositions and their uses are described. In particular, the described compositions can provide improved effectiveness in the dermatological treatment of pigmentation, without disadvantages experienced with other known compositions. The described topical compositions can comprise, in a physiologically acceptable medium, from 3% to 10% of rucinol or one of its salts. Also described, are methods of use treating pigmentation disorders of the skin with the described compositions.

Priority: FR20090053745 Applic. Date: 2009-06-05; US20080109061P Applic. Date: 2008-10-28; WO2009EP64238 Applic. Date: 2009-10-28

Inventor: ANDRES PHILIPPE [FR]; PELISSON ISABELLE [FR]

Title: BIOSURFACTANT COMPOSITION PRODUCED BY A NEW BACILLUS LICHENIFORMS STRAIN, USES AND PRODUCTS THEREOF

Applicant/Assignee:

Application No.: 13/131420   Filing Date: 25/Nov/2009

Abstract:

New Bacillus licheniformis strain named V9T14 that produces a new biosurfactant composition that is effective against colonization and/or bio film formation from bacteria. The new biosurfactant composition can be used in combination with biocides for preventing formation and/or for eradicating bacteria grown planktonically and/or as a biofilm, preferably on biotic and/or abiotic surfaces.

Priority: WO2008IB03583 Applic. Date: 2008-12-10; WO2009IB55334 Applic. Date: 2009-11-25

Inventor: CERI HOWARD [CA]; TURNER RAYMOND [CA]; MARTINOTTI MARIA GIOVANNA [IT]; RIVARDO FABRIZIO [IT]; ALLEGRONE GIANNA [IT]

Title: BIOMATERIALS FOR TISSUE REPLACEMENT

Applicant/Assignee:

Application No.: 13/129058   Filing Date: 12/Nov/2009

Abstract:

This invention relates to biomaterial compositions, methods and kits for producing hydrogels with tunable physico-chemical properties. Specifically, the invention relates to producing cellulosic hydrogels having optimized physico-chemical properties enabling support of cell growth or as replacement or filler for tissue repair, reconstruction or augmentation.

Priority: US20080114034P Applic. Date: 2008-11-12; WO2009US64254 Applic. Date: 2009-11-12

Inventor: NICOLL STEVEN B [US]; STALLING SIMONE S [US]; REZA ANNA T [US]

Title: Method for Preparing a Non-Ionic Surfactant Stable Personal Care Dispersion

Applicant/Assignee:

Application No.: 13/156749   Filing Date: 09/Jun/2011

Abstract:

Disclosed herein are methods for preparing dispersions containing small diameter, liquid crystals of a high charge density cationic polymer and a detersive surfactant. Also disclosed herein are uses of these dispersions to prepare personal care products and liquid cleansing products.

Priority: US20100352977P Applic. Date: 2010-06-09

Inventor: ROYCE DOUGLAS ALLAN [US]; WANING GREGORY THOMAS [US]; LINDBERG SETH EDWARD [US]; BROWN MARK ANTHONY [US]; PIATT DAVID MICHAEL [US]

Title: Substituted Pyrazole Compounds

Applicant/Assignee: MIIKANA THERAPEUTICS, INC

Application No.: 13/128656   Filing Date: 23/Nov/2009

Abstract:

Provided are substituted pyrazole compounds which are useful as protein kinase inhibitors, compositions comprising the compounds, and methods of use thereof. The protein kinase inhibitors are particularly for inhibition of Aurora A (Aurora-2) protein kinase and are useful in the treatment of diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer.

Priority: US20080118136P Applic. Date: 2008-11-26; WO2009US65496 Applic. Date: 2009-11-23

Inventor: LADOUCEUR GAETAN [US]; AGOSTO GREGORY A [US]; SHAH JAMSHED H [US]; SUWANDI LITA [US]; OFOEGBU NNAMDI [US]

Title: DERMATOLOGICAL/COSMETIC COMPOSITIONS COMPRISING A RETINOID AND BENZOYL PEROXIDE

Applicant/Assignee: GALDERMA RESEARCH & DEVELOPMENT

Application No.: 13/110814   Filing Date: 18/May/2011

Abstract:

Dermatological/cosmetic compositions contain, in a physiologically acceptable medium, at least one retinoid, dispersed benzoyl peroxide and a gelling system comprising at least two categories of compounds.

Priority: FR20060052967 Applic. Date: 2006-07-13; US2009-318938 Applic. Date: 2009-01-13; WO2007EP57091 Applic. Date: 2007-07-11; US20060832092P Applic. Date: 2006-07-21