Title: STACKABLE PLANT POT

Applicant/Assignee:

Application No.: 12/307288   Filing Date: 31/Aug/2007

Abstract:A stackable plant pot including a cavity provided with water flow directing gutters, a recesses centrally located water catchment region with drainage slits and suited to receive a moisture retaining device, and a soil holding region located above the water catchment region.

Priority: AU20060903563 Applic. Date: 2006-07-03; WO2007AU01422 Applic. Date: 2007-08-31

Inventor: KEATS JOHN RODNEY [AU]

Title: Piezoelectric atomizer comprising a fragrancing liquid composition

Applicant/Assignee: L'OREAL

Application No.: 12/496184   Filing Date: 01/Jul/2009

Abstract:The invention relates to a cosmetic assembly comprising: (A) a cosmetic or dermatological composition contained inside a reservoir, said composition being liquid and comprising, in a physiologically acceptable medium: (i) from 1 to 90% by weight of a fragrance concentrate

(ii) from 1 to 98.5% by weight of at least one non-volatile solvent for said concentrate having a density of less than 1

(iii) at least from 0.5% to 50% by weight of at least one volatile alcohol for said concentrate

said composition having a viscosity less than or equal to 8 mPa.s

the amounts being defined relative to the total weight of the composition

(B) a spraying device comprising a container containing said liquid cosmetic composition, equipped with a piezoelectric spraying mechanism that makes it possible to spray the cosmetic composition in the form of droplets. The invention also relates to a method of fragrancing human keratin materials and especially skin, lips, hair, scalp, nails, comprising at least one step of spraying a fragrancing composition by means of a device as defined previously. The invention also relates to a method of fragrancing the surrounding air comprising at least one step of spraying a fragrancing composition by means of a spraying device as defined previously.

Priority: FR20080054482 Applic. Date: 2008-07-02; US20080080518P Applic. Date: 2008-07-14

Inventor: BARA ISABELLE [FR]; ALBELDA VIRGINIE [FR]; CHARBONNIER-CIVIER CAROLE [FR]

Title: Antimicrobial Topical and Other Preparations Containing Fluorescent or Illumination Dye and Tracer Agents or Compounds

Applicant/Assignee:

Application No.: 12/498217   Filing Date: 06/Jul/2009

Abstract:A formulation for topical application to human skin and other surface preparation compositions containing antimicrobial, antifungal and antiviral compounds which remain on human skin and other surface compositions to reduce or dominate bacteria, virus and fungi present, prevent future contamination by their presence and substantive character, contain agents or compounds that contain antibacterial, antiviral and antifungal properties and flourescent dyes and tracers that contain illumination properties exhibiting various colons including clear and no color pigment, that when exposed to certain light such as ultraviolet, will produce an illumination effect in various colors including dear and no color for a period of time within a preferred range of thirty minutes to six hours or longer from the time of initial application, and prior to for instance application of ultraviolet light, such flourescent dyes and tracers appear to be clear in color, invisible or have no color pigment showing on the skin or other surfaces, but when exposed to for instance ultraviolet fight, the surface illuminates allowing a person to determine if human skin or other surface has been adequately covered with the antibacterial, antifungal or antiviral composition agent or compound, and to significantly increase the activity to reduce and eliminate bacteria, virus and fungi on the surface, and support programs for antibacterial, antifungal and antiviral quality control, compliance, verification and education for industry and human handwash technique.

Priority: US20080133936P Applic. Date: 2008-07-07

Inventor: STOLMEIER PATRICK JOHN [US]; STOLMEIER JONATHAN P [US]

Title: Silicone composition

Applicant/Assignee: MOMENTIVE PERFORMANCE MATERIALS, INC

Application No.: 12/217548   Filing Date: 07/Jul/2008

Abstract:This invention relates to silicone-containing compositions, method of making said silicone-containing compositions, and to personal care and other products based on such compositions.

Priority:

Inventor: WAHL ROY UWE [US]

Title: Nanoparticle hybrid sunscreens

Applicant/Assignee: ENERGY MATERIALS CORPORATION

Application No.: 12/459541   Filing Date: 02/Jul/2009

Abstract:The invention discloses and claims a new class of chemical compositions with ideal sunscreen properties. The chemical composition comprises spherical particles between 200 nm and 10 microns in diameter prepared by an emulsion polymerization of tetraalkoxysilanes or organotrialkoxysilanes or organobridged trialkoxysilanes with a dye monomer bearing two or more alkoxysilyl groups attached to the bridging chromophore. The resulting spheres absorb ultraviolet light. The dye can be any organic chromophore capable of receiving multiple trialkoxysilyl groups resulting in multipoint covalent attachment that precludes leaching of the dye from the spheres. The formic acid-toluene-monomer emulsion polymerization allows for large-scale (>100 gram) synthesis of monodisperse particles under acidic, non-aqueous conditions without surfactants. The particles less than 1 micron in diameter are smooth as talc to the touch and will provide a smooth formulation for sunscreen creams or lotions.

Priority: US20080133875P Applic. Date: 2008-07-02

Inventor: LOY DOUGLAS ANSON [US]; SHEA KENNETH J [US]; BODAY DYLAN J [US]; WERTZ JASON T [US]

Title: Cosmetic Composition Containing A Protein And An Enzyme Inhibitor

Applicant/Assignee:

Application No.: 12/541439   Filing Date: 14/Aug/2009

Abstract:The present invention is a cosmetic composition comprising a water-soluble protein-based film-forming agent, the film-forming agent having a tertiary structure capable of undergoing a helix-coil transformation, a protease inhibitor in an amount sufficient to protect the protein on the stratum corneum and a cosmetically acceptable vehicle so that the protease inhibitor prolongs the pulling effect of the film-forming agent.

Priority: US2005-030664 Applic. Date: 2005-01-06; US20040535198P Applic. Date: 2004-01-07

Inventor: GIACOMONI PAOLO ULDERICO [US]; MANIRAZMAN ABUL M [US]; LENTINI PETER J [US]; HARVEY GEDEON [US]

Title: Photoprotective compositions comprising photosensitive 1,3,5-triazine compounds, dibenzoylmethane compounds and siliceous s-triazines substituted with two aminobenzoate or aminobenzamide groups

Applicant/Assignee: L'OREAL

Application No.: 11/987212   Filing Date: 28/Nov/2007

Abstract:UV-photoprotective, topically applicable cosmetic/dermatological compositions contain: (a) at least one dibenzoylmethane compound, (b) at least one 1,3,5-triazine compound that is photosensitive in the presence of a dibenzoylmethane compound, and (c) at least one siliceous s-triazine compound substituted with two aminobenzoate or aminobenzamide groups, or a tautomeric form thereof, the 1,3,5-triazine compounds being improvedly photostable in such compositions.

Priority: FR20060055164 Applic. Date: 2006-11-28; US20060873000P Applic. Date: 2006-12-06

Inventor: CANDAU DIDIER [FR]; RICHARD HERVE [FR]

Title: Skin Care Products, As Well As Foods and Beverages Containing 6-O-PUFA Ascorbic Esters

Applicant/Assignee: SUNTORY HOLDINGS LIMITED

Application No.: 12/558986   Filing Date: 14/Sep/2009

Abstract:Skin care products which contain as a vitamin C component 6-O-PUFA ascorbates represented by general formula (I): RCO-A (I) where RCO- is an acyl group derived from a polyunsaturated fatty acid, and A is a residue of ascorbic acid that binds by -O- derived from the hydroxyl group in ascorbic acid. The products show improved transfer of ascorbic acid to tissues or cells, allow the functions of ascorbic acid to be exhibited efficiently, and also have the potential to show the functions of PUFAs. Also provided are foods and beverages that contain 6-O-PUFA ascorbates represented by general formula (I).

Priority: JP20040237942 Applic. Date: 2004-08-18; US2007-660211 Applic. Date: 2007-02-15; WO2005JP15383 Applic. Date: 2005-08-18

Inventor: FUKAMI HARUKAZU [JP]; KAWASHIMA HIROSHI [JP]; ONO YOSHIKO [JP]

Title: POLYPEPTIDE CONSTRUCTS FOR TOPICAL ADMINISTRATION

Applicant/Assignee: ABLYNX N.V

Application No.: 12/487895   Filing Date: 19/Jun/2009

Abstract:The invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention further relates to anti-IgE therapeutic molecules.

Priority: EP20030447005 Applic. Date: 2003-01-10; WO2003EP06581 Applic. Date: 2003-06-23; WO2003EP07313 Applic. Date: 2003-07-08; US2005-534292 Applic. Date: 2005-05-09; WO2003BE00190 Applic. Date: 2003-11-07; US20020425073P Applic. Date: 2002-11-08; US20020425063P Applic. Date: 2002-11-08

Inventor: SILENCE KAREN [BE]; VAECK MARK [BE]; VAN BERGEN EN HENEGOUWEN PAUL M P [NL]

Title: FINE-GRANULOMETRY FUNGAL EXTRACT CHITINE-GLUCANE

Applicant/Assignee:

Application No.: 12/312656   Filing Date: 20/Nov/2007

Abstract:The present invention relates to a chitin-glucan copolymer in the form of micrometric particles. The present invention in particular provides a composition containing a chitin-glucan copolymer in the form of micrometric particles for the preparation of cosmetic compositions, and in particular dermatological or dermocosmetic compositions. In particular, the present invention relates to a cosmetic composition for face or body care, such as hydrating, firming or smoothing the skin, and exercising an anti-aging effect, including an anti-wrinkle effect. The purpose of the invention is also to provide a porous material that can for example be used in tissue engineering or cell culture, or that can be used as a material in the cosmetics or pharmaceutical industry.

Priority: FR20060054998 Applic. Date: 2006-11-20; WO2007EP62601 Applic. Date: 2007-11-20

Inventor: GAUTIER SANDRINE [BE]; BRUYERE JEAN-MICHEL [BE]; MAQUET VERONIQUE [BE]

Title: Antimicrobial Composition

Applicant/Assignee:

Application No.: 12/304204   Filing Date: 13/Jun/2007

Abstract:Use of a composition comprising hyaluronic acid or a pharmaceutically acceptable salt thereof, in the manufacture of a topical medicament for antimicrobial treatment of the skin or mucosa.

Priority: IT2006MI01132 Applic. Date: 2006-06-13; WO2007GB02197 Applic. Date: 2007-06-13

Inventor: MASTRODONATO MARCO [IT]

Title: Method and Composition for the Treatment of Skin Conditions

Applicant/Assignee:

Application No.: 12/330281   Filing Date: 08/Dec/2008

Abstract:The present invention relates to artificial seawater and its use to treat a variety of skin conditions, when that sea water has more magnesium in it than in naturally occurring seawater. The treatment of acne would healing and the like can be improved with the product of the present invention and with treatments thereof.

Priority: US2008-166605 Applic. Date: 2008-07-02

Inventor: WILLEFORD KENNETH L [US]

Title: Cosmetic Skincare Method Employing Mechanical Stresses

Applicant/Assignee: L'OREAL

Application No.: 12/085225   Filing Date: 17/Nov/2006

Abstract:The present invention concerns in particular a cosmetic skincare method comprising the simultaneous or sequential application: (i) of a composition comprising at least one agent increasing the expression of mechano-receptors in the cells of the skin

(ii) of a device intended to apply and/or maintain, controlledly, mechanical stresses to/on the skin. It also relates to a cosmetic kit comprising at least a composition comprising at least one agent increasing the expression of mechanoreceptors in the cells of the skin

and a device intended to apply and/or maintain, controlledly, mechanical stresses to/on the skin. The joint use of said composition and said device makes it possible to potentiate and/or prolong the effect of mechanical stresses induced by the application of said device on the improvement in the thickness of the skin, the improvement in the radiance of the complexion, the improvement in the density of the skin and/or the improvement in the mechanical properties of the skin (firmness, elasticity, tonicity) and/or to promote regeneration of the skin and/or its cicatrization.

Priority: FR20050053527 Applic. Date: 2005-11-21; US20050741912P Applic. Date: 2005-12-05; WO2006EP68630 Applic. Date: 2006-11-17

Inventor: CASSIN GUILLAUME [FR]

Title: EXCITATORY AMINO ACID INHIBITORS FOR TREATING SENSITIVE SKINS

Applicant/Assignee: L'OREAL

Application No.: 12/556901   Filing Date: 10/Sep/2009

Abstract:Sensitive human skin/scalp/mucous membrane conditions, for example skin irritation and/or dry patches and/or erythemas and/or dysaesthesic sensations and/or sensations of heating and/or pruritus, are therapeutically treated by topically applying thereto an effective condition-alleviating amount of at least one inhibitor of at least one excitatory amino acid.

Priority: FR19970011959 Applic. Date: 1997-09-25; US2003-401685 Applic. Date: 2003-03-31; US1998-160151 Applic. Date: 1998-09-25

Inventor: BRETON LIONEL [FR]; NONOTTE ISABELLE [FR]

Title: Recombinant Staphylococcal Phage Lysin as an Antibacterial Agent

Applicant/Assignee:

Application No.: 12/308796   Filing Date: 29/Jun/2007

Abstract:The present invention provides a plasmid pSOFLysK contained in the bacterial strain Lactococcus lactis NZ9800 referred herein as Lactococcus lactis NZ9800-pSOFLysK (subsequently designated Lactococcus lactis DPC6132) encoding anti-staphylococcal activity as deposited with DSMZ under accession No. ncimb 41409 and plasmids substantially similar thereto also providing anti-staphylococcal activity. In another aspect, the present invention provides a gene encoding an anti-staphylococcal protein, Lysin (LysK) as encoded by the plasmid pSOFLysK in Lactococcus lactis/VZ9800-pSOFLysK (subsequently designated Lactococcus lactis DPC6132). The recombinant lysine also has applications in diagnostics given its lytic mechanism.

Priority: IE20060000488 Applic. Date: 2006-06-29; WO2007IE00064 Applic. Date: 2007-06-29

Inventor: ROSS PAUL [IE]; COFFEY AIDAN [IE]

Title: ELECTROSTATICALLY CHARGED MULTI-ACTING NASAL APPLICATION, PRODUCT, AND METHOD

Applicant/Assignee: TRUTEK CORP

Application No.: 12/467271   Filing Date: 16/May/2009

Abstract:A product to reduce and method of reducing the risk of inhalation of harmful substances by applying a formulation composition to a substrate or the skin in close proximity of one or more nostrils. This formulation, when applied creates an electrostatic field having a charge. The electrostatic field attracts airborne particulates of opposite charge to the substrate that are in close proximity to the substrate close to the skin and a biocidic agent renders microorganisms coming in contact the substrate or skin less harmful.

Priority: US20080085555D Applic. Date: 2008-08-01; US20080078478P Applic. Date: 2008-07-07; US20080078472P Applic. Date: 2008-07-07

Inventor: WAHI ASHOK [US]

Title: BIOSURFACTANT-CONTAINING SKIN CARE COSMETIC AND SKIN ROUGHNESS-IMPROVING AGENT

Applicant/Assignee: TOYO BOSEKI KABUSHIKI KAISHA NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCEAND TECHNOLOGY

Application No.: 12/094727   Filing Date: 21/Nov/2006

Abstract:The present invention relates to a cosmetic for skin roughness improvement/skin care containing a biosurfactant, particularly MEL-A, MEL-B or MEL-C.

Priority: JP20050340902 Applic. Date: 2005-11-25; JP20060172238 Applic. Date: 2006-06-22; WO2006JP323239 Applic. Date: 2006-11-21

Inventor: KITAGAWA MASARU [JP]; SUZUKI MICHIKO [JP]; YAMAMOTO SHUHEI [JP]; SOGABE ATSUSHI [JP]; KITAMOTO DAI [JP]; IMURA TOMOHIRO [JP]; FUKUOKA TOKUMA [JP]; MORITA TOMOTAKE [JP]

Title: SENSOR

Applicant/Assignee: DAYTON TECHNOLOGIES LIMITED

Application No.: 12/195281   Filing Date: 20/Aug/2008

Abstract:A sensor for sensing physiological signal from outside the human body, said sensor comprising an electrode for abutment against the skin

and a transmission conductor electrically connected to said electrode, said transmission conductor formed from a flexible material, wherein in use a substrate is disposed between the skin and said transmission conductor, and said substrate is permeable to moisture and air thereby exposing said transmission conductor to said moisture.

Priority: HK20080107402 Applic. Date: 2008-07-04

Inventor: YUEN PAUL ANTHONY [CN]

Title: Applicator, a packaging and applicator device including such an applicator, a method of manufacturing such an applicator, and a machine for manufacturing such an applicator

Applicant/Assignee: L'OREAL

Application No.: 12/585333   Filing Date: 11/Sep/2009

Abstract:An applicator for applying a cosmetic or a skin care product may include a stem including at least one stamped portion forming a joint, and an applicator member disposed at a first end of the stem.

Priority: FR20050051825 Applic. Date: 2005-06-29; US2006-474313 Applic. Date: 2006-06-26; US20050701063P Applic. Date: 2005-07-21

Inventor: GUERET JEAN-LOUIS [FR]

Title: Whitening agent

Applicant/Assignee: SHISEIDO COMPANY, LTD

Application No.: 12/585271   Filing Date: 10/Sep/2009

Abstract:A whitening agent containing a solvent extract of a plant Elephantopus mollis H. B. & K. belonging to Compositae having a superior whitening action and having a superior effect in lightening and whitening pigmentation after suntans, senile lentigo, freckles, melasma, is provided.

Priority: JP20040277298 Applic. Date: 2004-09-24; US2007-662284 Applic. Date: 2007-03-09; WO2005JP17434 Applic. Date: 2005-09-15

Inventor: UMISHIO KENICHI [JP]; MAEDA KAZUHISA [JP]; KOBAYASHI KOJI [JP]

Title: METHODS AND KITS IMPARTING BENEFITS TO KERATIN-CONTAINING SUBSTRATES

Applicant/Assignee:

Application No.: 12/169984   Filing Date: 09/Jul/2008

Abstract:This invention relates to methods for providing cosmetic or other benefits to keratin-containing substrates by sequential treatment with cationically and anionically charged compounds, and compositions and kits containing them.

Priority:

Inventor: DALY SUSAN [US]; JACHOWICZ JANUSZ [US]; BIANCHINI ROBERT [US]

Title: COMPOSITION FOR PROVIDING A BENEFIT TO A KERATIN-CONTAINING SUBSTRATE

Applicant/Assignee:

Application No.: 12/170007   Filing Date: 09/Jul/2008

Abstract:This invention relates to compositions and methods for providing cosmetic and other potential benefits to keratin-containing substrates. The compositions contain at least one naturally-occurring cationic protein with a biological function in a cosmetically acceptable carrier, such that the naturally-occurring cationic protein retains its essential configuration, preserving its biological function, when it is in proximity to a keratin-containing substrate.

Priority:

Inventor: DALY SUSAN [US]; JACHOWICZ JANUSZ [US]; BIANCHINI ROBERT [US]

Title: Beauty/medication patch

Applicant/Assignee:

Application No.: 12/585466   Filing Date: 16/Sep/2009

Abstract:A beauty/medication patch including a substrate, an outer layer, and a medication lotion

the outer layer being made of a degradable material being disposed on the substrate

one or a plurality of micro-probe array being disposed on a surface of the outer layer

the medication lotion being coated between the substrate and the outer layer, and/or admixed in the substrate

the patch being attached to a human skin, the micro-probe array piercing through a stratum corneum layer of the human skin and naturally being degraded by human skin or absorbed and metabolized by a human body

and the medication lotion penetrating into the skin and being absorbed by the human skin.

Priority: TW20070114662 Applic. Date: 2007-04-25; US2007-979388 Applic. Date: 2007-11-02

Inventor: MENG HSIEN KAI [TW]; HSIEH SHU PIN [TW]; YEH YUAN YI [TW]; LIN CHANG WEI [TW]

Title: Compositions And Methods For Wound Healing

Applicant/Assignee: UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL

Application No.: 12/542377   Filing Date: 17/Aug/2009

Abstract:The present invention is related to the field of wound healing or tissue regeneration due to disease (i.e., for example, cardiovascular diseases, osteoarthritic diseases, or diabetes). In particular, the present invention provides compositions and methods comprising molecules with linked alpha-gal epitopes for induction of recruitment of macrophages localized within or surrounding damaged tissue. The recruited macrophages and stem cells promote the repair and regeneration of the treated injured tissue. In some embodiments, the present invention provides treatments for tissue repair in normal subjects and in subjects having impaired healing capabilities, such as diabetic and aged subjects. In some embodiments, the present invention provides treatments for injured tissues such as brain, peripheral nerve, muscle, cartilage, bone, gastrointestinal tract and dysfunctional endocrine tissues.

Priority: WO2008US08731 Applic. Date: 2008-07-17; US20070961047P Applic. Date: 2007-07-17

Inventor: GALILI URI [US]

Title: DEHYDROEPIANDROSTERONE PRODUCTION PROMOTER AND USE THEREOF

Applicant/Assignee: ARKRAY, INC

Application No.: 12/307667   Filing Date: 30/Jan/2008

Abstract:A new orally administerable DHEA production promoter is provided. A composition containing an extract of at least one selected from the group consisting of plants of Rosaceae Crataegus, Saururaceae Houttuynia, Vitaceae Vitis, and Compositae Anthemis is provided as a DHEA production promoter. The extract may be of one of the plants or extracts of two or more of them may be used in combination. A specific example is preferably a mixture of extracts of all four of the aforementioned plants. This DHEA production promoter also can be used as, for example, an anti-aging agent such as a skin improver as well as a pharmaceutical agent such as an immunostimulator, an antidiabetic agent, an anti-osteoporosis agent, an antiarteriosclerotic agent, an anti-obesity agent, a sleep-promoting agent, and a central nervous system depressant.

Priority: JP20070073415 Applic. Date: 2007-03-20; WO2008JP51421 Applic. Date: 2008-01-30

Inventor: YAGI MASAYUKI [JP]; KAWAL HIROSHIGE [JP]; KUBO MOTOKI [JP]; YONEI YOSHIKAZU [DE]; MATSUURA NOBUYASU [JP]

Title: ASSOCIATION OF A TENSOR AGENT OR DEVICE AND A SACCHARIDE COMPOUND

Applicant/Assignee: L'OREAL

Application No.: 12/299563   Filing Date: 04/May/2007

Abstract:The invention concerns a composition for topical application on the skin comprising, in a physiological acceptable medium, at least one saccharide compound which augments the expression of mechanoreceptors in skin cells and at least one tensor agent. The invention also concerns a skin care health kit comprising (a) a composition comprising at least one tensor agent and (b) a composition comprising at least one saccharide compound which increases the expression of mechanoreceptors in skin cells. The invention also concerns a kit comprising (a) a composition comprising at least one saccharide compound which augments the expression of mechanoreceptors in skin cells and (b) a tensor device designed to apply and/or maintain in a controlled manner mechanical constraints on the skin. The invention also concerns a process for cosmetic treatment of the skin comprising the simultaneous or sequential application of said compositions and/or tensor devices.

Priority: FR20060051644 Applic. Date: 2006-05-05; FR20060051645 Applic. Date: 2006-05-05; US20060800409P Applic. Date: 2006-05-16; US20060800410P Applic. Date: 2006-05-16; WO2007FR51222 Applic. Date: 2007-05-04

Inventor: LABOUREAU JULIEN [FR]; CASSIN GUILLAUME [FR]

Title: HYDROXYLATED AMIDE SKIN MOISTURIZER

Applicant/Assignee: L'OREAL

Application No.: 12/302398   Filing Date: 03/May/2007

Abstract:The invention relates to the cosmetic use, as a skin moisturizer, of a compound of formula (I): with (i) R1 and R2 represent a hydrogen atom or a C1-C6-alkyl group, or (ii) R1 and R2 can form, together with the nitrogen atom which bears them, a saturated heterocycle with 5 to 7 ring members

R5 representing a hydrogen atom or a (C1-C3) alkyl group

R6 representing a hydrogen atom or a (C1-C4) alkyl group

R3 represents a hydrogen atom or a (C1-C6) alkyl-group, or -OR3 represents a phosphate group

it being possible for the two groups R3 to form, together, an isopropylidene group

R4 represents a hydrogen atom or -OR4 represents a-phosphate group

and the salts, solvates and isomers thereof. The invention also relates to a cosmetic composition comprising a compound (I) and the corresponding new compounds.

Priority: FR20060051987 Applic. Date: 2006-05-31; US20060811094P Applic. Date: 2006-06-06; WO2007EP54278 Applic. Date: 2007-05-03

Inventor: MARAT XAVIER [FR]

Title: 2-Methylene-(20E)-20(22)-Dehydro-19-Nor-Vitamin D Analogs

Applicant/Assignee:

Application No.: 12/171045   Filing Date: 10/Jul/2008

Abstract:This invention discloses 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs, and specifically 2-methylene-(20E)-20(22)-dehydro-19-nor-1alpha,25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits relatively high transcription activity as well as pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also shows lower activity in vivo on bone calcium mobilization and similar in vivo intestinal calcium transport activity compared to the native hormone 1alpha,25-dihydroxyvitamin D3, and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.

Priority:

Inventor: DELUCA HECTOR F [US]; TADI BULLI PADMAJA [US]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: 2-Methylene-20(21)-Dehydro-19-Nor-Vitamin D Analogs

Applicant/Assignee:

Application No.: 12/171056   Filing Date: 10/Jul/2008

Abstract:This invention discloses 2-methylene-20(21)-dehydro-19-nor-vitamin D analogs, and specifically 2-methylene-20(21)-dehydro-19-nor-1alpha,25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits relatively high transcription activity as well as pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also shows lower activity in vivo on bone calcium mobilization and similar in vivo intestinal calcium transport activity compared to the native hormone 1alphaa,25-dihydroxyvitamin D3, and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.

Priority:

Inventor: DELUCA HECTOR F [US]; TADI BULLI PADMAJA [US]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: 2-Methylene-(17Z)-17(20)-Dehydro-19,21-Dinor-Vitamin D Analogs

Applicant/Assignee:

Application No.: 12/171071   Filing Date: 10/Jul/2008

Abstract:This invention discloses 2-methylene-(17Z)-17(20)-dehydro-19,21-dinor-vitamin D analogs, and specifically 2-methylene-(17Z)-17(20)-dehydro-19,21-dinor-1alpha, 25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits relatively high transcription activity as well as pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also has significant calcemic activity in vivo having about the same bone calcium mobilization activity and intestinal calcium transport activity as the native hormone 1alpha,25-dihydroxyvitamin D3, and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.

Priority:

Inventor: DELUCA HECTOR F [US]; TADI BULLI PADMAJA [US]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: 2-Methylene-(22E)-25-(1-Methylene-Hexyl)-26,27-Cyclo-22-Dehydro-19-Nor-Vitamin D Analogs

Applicant/Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION

Application No.: 12/171094   Filing Date: 10/Jul/2008

Abstract:This invention discloses 2-methylene-(22E)-25-(1-methylene-hexyl)-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs, and specifically 2-methylene-(22E)-25-(1-methylene-hexyl)-26,27-cyclo-22-dehydro-19-nor-1alpha,24(R)-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits relatively high transcription activity as well as pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion.

This compound also shows lower activity in vivo on bone calcium mobilization and intestinal calcium transport activity compared to the native hormone 1alpha,25-dihydroxyvitamin D3, and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.

Priority:

Inventor: DELUCA HECTOR F [US]; BARYCKI RAFAL [US]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: 19-Nor-Vitamin D Analogs with 1,2-Dihydrofuran Ring

Applicant/Assignee:

Application No.: 12/171103   Filing Date: 10/Jul/2008

Abstract:19-nor-vitamin D analogs having an additional dihydrofuran ring connecting the 1alpha-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro and in vivo activities, making them therapeutic agents for the treatment or prophylaxis of autoimmune diseases, some types of cancers, secondary hyperparathyroidism, psoriasis, or other skin diseases.

Priority:

Inventor: DELUCA HECTOR F [US]; GLEBOCKA AGNIESZKA [US]; SOKOLOWSKA KATARZYNA [PL]; SICINSKI RAFAL R [PL]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: 19-NOR-VITAMIN D ANALOGS WITH 3,2-DIHYDROFURAN RING

Applicant/Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION

Application No.: 12/171108   Filing Date: 10/Jul/2008

Abstract:19-nor-vitamin D analogs having an additional dihydrofuran ring connecting the 3beta-oxygen and carbon-2 of the A-ring of the analog, and pharmaceutical uses therefore, are described. These compounds exhibit selective in vitro and in vivo activities, making them therapeutic agents for the treatment or prophylaxis of autoimmune diseases, some types of cancers, metabolic bone diseases, osteomalacia, osteopenia, secondary hyperparathyroidism, psoriasis, or other skin diseases.

Priority:

Inventor: DELUCA HECTOR F [US]; GLEBOCKA AGNIESZKA [US]; SOKOLOWSKA KATARZYNA [PL]; SICINSKI RAFAL R [PL]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: 2-Methylene-19,26-Dinor-(20R,22E,25R)-Vitamin D Analogs

Applicant/Assignee:

Application No.: 12/171113   Filing Date: 10/Jul/2008

Abstract:This invention discloses 2-methylene-19,26-dinor-(20R,22E,25R)-vitamin D analogs, and specifically 2-methylene-19,26-dinor-(20R,22E,25R)-1alpha,25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits transcription activity as well as pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also shows very low activity in vivo on bone calcium mobilization and relatively high intestinal calcium transport activity compared to the native hormone 1alpha,25-dihydroxyvitamin D3, and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.

Priority:

Inventor: DELUCA HECTOR F [US]; CHIELLINI GRAZIA [US]; GRZYWACZ PAWEL [US]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: 2-Methylene-19,26-Dinor-(20S,22E,25R)-Vitamin D Analogs

Applicant/Assignee:

Application No.: 12/171120   Filing Date: 10/Jul/2008

Abstract:This invention discloses 2-methylene-19,26-dinor-(20S,22E,25R)-vitamin D analogs, and specifically 2-methylene-19,26-dinor-(20S,22E,25R)-1alpha,25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits transcription activity as well as pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also shows no activity in vivo on bone calcium mobilization and relatively low intestinal calcium transport activity compared to the native hormone 1alpha,25-dihydroxyvitamin D3, and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.

Priority:

Inventor: DELUCA HECTOR F [US]; CHIELLINI GRAZIA [US]; GRZYWACZ PAWEL [US]; PLUM LORI A [US]; CLAGETT-DAME MARGARET [US]

Title: Novel Tyrosinase inhibitors and pharmaceutical/cosmetic applications thereof

Applicant/Assignee: GALDERMA RESEARCH & DEVELOPMENT

Application No.: 12/318902   Filing Date: 12/Jan/2009

Abstract:Compounds corresponding to the following general formula (I): are formulated into pharmaceutical compositions useful in human or veterinary medicine or else into cosmetic compositions

novel compounds of formula (II) are also thus useful:

Priority: FR20060052908 Applic. Date: 2006-07-11; WO2007EP57019 Applic. Date: 2007-07-10; US20060831210P Applic. Date: 2006-07-17

Inventor: SUZUKI ITARU [FR]; ERDELMEIER IRENE [FR]; YADAN JEAN-CLAUDE [FR]; PELISSON ISABELLE [FR]

Title: HIGH PENETRATION PRODRUG COMPOSITIONS OF RETINOIDS AND RETINOID-RELATED COMPOUNDS

Applicant/Assignee:

Application No.: 12/503739   Filing Date: 15/Jul/2009

Abstract:The invention provides compositions of novel high penetration compositions (HPC) or high penetration prodrugs (HPP) of retinoids and retinoid-related compounds, which are capable of crossing biological barriers with high penetration efficiency. The HPPs are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, the HPPs are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPPs can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.

Priority: WO2007IB50122 Applic. Date: 2007-01-15

Inventor: YU CHONGXI [US]

Title: DERMATOLOGICAL COMPOSITIONS WITH ANTI-AGING AND SKIN EVEN-TONING PROPERTIES

Applicant/Assignee:

Application No.: 12/499042   Filing Date: 07/Jul/2009

Abstract:The present invention relates to methods and compositions comprising benzoquinones such as Duroquinone, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.

Priority: US20080134516P Applic. Date: 2008-07-09

Inventor: HINMAN ANDREW W [US]; MILLER GUY M [US]

Title: System for Noninvasive Determination of Analytes in Tissue

Applicant/Assignee:

Application No.: 12/562050   Filing Date: 17/Sep/2009

Abstract:An apparatus and method for noninvasive determination of analyte properties of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems can include an illumination/modulation subsystem, a tissue sampling subsystem, a data acquisition subsystem, a computing subsystem, and a calibration subsystem. The invention can provide analyte property determination and identity determination or verification from the same spectroscopic information, making unauthorized use or misleading results less likely than in systems that use separate analyte and identity determinations. The invention can be used to control and monitor individuals accessing controlled environments.

Priority: US2006-515565 Applic. Date: 2006-09-05; US2005-305964 Applic. Date: 2005-12-19; US2004-852415 Applic. Date: 2004-05-24; US2001-832585 Applic. Date: 2001-04-11; US2002-281576 Applic. Date: 2002-10-28; US2003-378237 Applic. Date: 2003-03-03; US2004-753506 Applic. Date: 2004-01-08; US20090147107P Applic. Date: 2009-01-25

Inventor: RIDDER TRENT [US]; VER STEEG BEN [US]; MCNALLY JAMES [US]; MAYNARD JOHN [US]; ABBINK RUSSELL [US]; MILLS MIKE [US]; LAAKSONEN BENTLEY [US]

Title: UNDERGARMENT FOR INCONTINENT PERSON AND TREATMENT DEVICE CONNECTED TO AN UNDERGARMENT

Applicant/Assignee:

Application No.: 12/441026   Filing Date: 12/Sep/2007

Abstract:The present invention relates to an undergarment (1) comprising: a supporting part (2) which surrounds at least the hips and the top of each thigh

and a flexible collecting bag (10) positioned in the crotch.

Priority: FR20060053719 Applic. Date: 2006-09-13; WO2007FR51926 Applic. Date: 2007-09-12

Inventor: PIETTE FRANCOIS [FR]; TAMBRUN ROGER [FR]

Title: NON-INVASIC THERAPEUTIC TREATMENT DEVICE

Applicant/Assignee: SYBARITIC, INC

Application No.: 12/437142   Filing Date: 07/May/2009

Abstract:A non-invasive therapeutic device includes a housing comprising a cavity and a bottom surface. A plurality of light emitting arrays are positioned within the bottom surface. At least one fan positioned within the cavity to provide at least cooling to the patient. The device includes a controller positioned on the housing for controlling the plurality of light emitting arrays and the at least one fan such that a phototherapy treatment can be applied to a selected region of a patient.

Priority: US20080051209P Applic. Date: 2008-05-07

Inventor: DAFFER STEVEN J [US]

Title: Clothing Protector

Applicant/Assignee:

Application No.: 12/354687   Filing Date: 15/Jan/2009

Abstract:Systems and methods for providing clothing protection are discussed herein. A clothing protector comprises a pad and an adhesive surface. The pad is configured to provide a layer between an outer clothing and skin. The pad extends below an upper edge of a diaper. The adhesive surface is coupled to the pad, wherein the adhesive surface is configured to attach to an inside of the outer clothing.

Priority: US20080011330P Applic. Date: 2008-01-15

Inventor: LEE PEARL POON [US]

Title: Compositions for Improving Skin Conditions Comprising Alpha-Bisabolol as an Active Ingredient

Applicant/Assignee: BIOSPECTRUM INC

Application No.: 12/527756   Filing Date: 27/Feb/2008

Abstract:The present invention relates to a composition for improving skin condition comprising alpha-bisabolol as an active ingredient. alpha-Bisabolol used as an active ingredient has greater skin whitening effect inhibiting melanin synthesis by inhibiting intracellular tyrosinase activities compared to arbutin used as an existing skin whitening agent. In addition, alpha-bisabolol exhibits the inhibition effect on collagenase activity and promotion effect on collagen biosynthesis at a molecular level, contributing to excellent efficacy in improvement of skin wrinkles. Meanwhile, alpha-bisabolol indicates the improvement effects on UV-induced skin damage and the skin growth promotion or hair loss prevention. Therefore, alpha-bisabolol has the excellent improvement effects on skin condition. Furthermore, alpha-bisabolol has the excellent anti-obesity and anti-oxidation effects. The composition of this invention can be applied to cosmetic, pharmaceutical and food composition having no cytotoxicities and side effects with safety.

Priority: KR20070019899 Applic. Date: 2007-02-27; WO2008KR01141 Applic. Date: 2008-02-27

Inventor: PARK DEOK HOON [KR]; KIM SAE BOM [KR]; LEE JONG SUNG [KR]

Title: Cosmetic Makeup and/or Care Process

Applicant/Assignee: L'OREAL

Application No.: 11/988158   Filing Date: 13/Jul/2006

Abstract:The present invention relates to a cosmetic process for making up and/or caring for keratin material(s), comprising the application, on contact with a keratin material, of a cosmetic composition comprising at least 75% by weight of compound(s) approved for food use relative to its total weight and having a covering power of greater than or equal to 30.

Priority: FR20050052205 Applic. Date: 2005-07-13; US20050712105P Applic. Date: 2005-08-30; WO2006IB52391 Applic. Date: 2006-07-13

Inventor: BLIN XAVIER [FR]

Title: EPITHELIUM-IMPROVING AGENT

Applicant/Assignee:

Application No.: 12/519671   Filing Date: 19/Feb/2008

Abstract:It is intended to provide an epithelium improving agent which improves the epithelial functions of various organs and, therefore, is usable in growing melanin-pigmented hair, relieving inflammatory symptoms in gingivitis and paradentitis, treating and relieving cold syndrome and bronchial asthma and, moreover, restoring sexual sensibility. An epithelium improving agent which comprises coenzyme Q10, cysteine, vitamins A, C and E and a skin extract of a rabbit inoculated with a vaccinia virus as the main components. In the case of treating gingivitis, paradentitis, cold syndrome and bronchial asthma, loratadine is further added. To an epithelium improving agent which is to be used in stimulating hair growth or restoring sexual sensibility, liquid paraffin and a hydrophilic ointment is further added to give a cream. Thus, the above problem can be solved.

Priority: JP20070104316 Applic. Date: 2007-03-13; JP20070279618 Applic. Date: 2007-09-27; WO2008JP53137 Applic. Date: 2008-02-19

Inventor: KOBAYASHI HARUZO [JP]

Title: Therapy With CD4 Binding Peptides and Radiation

Applicant/Assignee: GENMAB A/S

Application No.: 11/990581   Filing Date: 18/Aug/2006

Abstract:The present invention relates to a peptide, such as an antibody, capable of binding to CD4 and use thereof for the mediation of radiation treatment of a clinical condition. The radiation treatment may for instance by treatment with PUVA.

Priority: US20050709943P Applic. Date: 2005-08-18; WO2006DK00454 Applic. Date: 2006-08-18

Inventor: PARREN PAUL [NL]; BAADSGAARD OLE [DK]; ALEXANDER DENIS [GB]

Title: MACRO-SIZED LIPID CAPSULE EMULSION COMPOSITION AND COSMETIC COMPOSITION CONTAINING THE SAME

Applicant/Assignee: AMOREPACIFIC CORPORATION

Application No.: 12/300251   Filing Date: 30/Nov/2006

Abstract:An emulsion composition of the invention has macro-sized (0.01 to 5 mm) lipid capsule particles and it is for a skin cosmetic composition. An emulsion composition of the invention exhibits improved stability for its particle size by adjusting a size of the particle through a combination of liquid phase oil and integument lipid or lipoid material and encapsulating the liquid phase oil with the integument lipid. The emulsion composition of the invention has unique outward appearance and use feeling due to the macro-sized particles in it, also exhibits excellent skin safety and moisture persistence by containing no surfactant and maintains an activity of an oleophilic effective ingredient which is apt to be oxidized for a long time.

Priority: KR20060042420 Applic. Date: 2006-05-11; WO2006KR05111 Applic. Date: 2006-11-30

Inventor: KANG CHAN KOO [KR]; KANG HAK HEE [KR]; PARK CHANG HOON [KR]; HAN SANG HOON [KR]

Title: Preparation for reducing and/or preventing body fat and respective uses, in particular together with a dressing material

Applicant/Assignee:

Application No.: 12/439220   Filing Date: 28/Aug/2007

Abstract:The present invention relates to human metabolism, in particular fat reduction and a cosmetic and pharmaceutical formulation, as well as respective uses in particular together with a dressing material according to the invention.

Priority: DE200610042113 Applic. Date: 2006-09-07; US20060840779P Applic. Date: 2006-08-28; WO2007EP07508 Applic. Date: 2007-08-28

Inventor: HASSLER GERARD [CH]

Title: MICROPHASIC MICRO-COMPONENTS AND METHODS FOR CONTROLLING MORPHOLOGY VIA ELECTRIFIED JETTING

Applicant/Assignee:

Application No.: 12/506712   Filing Date: 21/Jul/2009

Abstract:The disclosure provides methods for preparation of multiphasic micro-components, such as core-shell or anisotropic (e.g., Janus) multiphasic particles with well-defined structures using electrohydrodynamic co-jetting of two polymer solutions containing polyelectrolytes. Suitable polyelectrolytes include polyacrylic acid (PAA), poly(acrylamide acrylic acid (PAAm), and/or poly(acryl amide-co-acrylic acid) (PAAm-AA), sodium polystyrene sulfonate (PSS), polyethylene imine (PEI), polypeptides, copolymers, and combinations of these. Control of certain variables, such as relative conductivities of the two jetting solutions, controls the particle morphologies formed, leading to a predetermined phase orientation for the same polymer system. In certain aspects, after cross-linking, core-shell particles are stable in aqueous solutions and exhibit reproducible swelling behavior, while maintaining the original core-shell geometry. In addition, micro-components formed in accordance with the present teachings are pH-responsive based on external environmental pH. Thus, such micro-components are useful for a variety of different applications, including micro- and nano-active ingredient delivery systems.

Priority: US2007-763842 Applic. Date: 2007-06-15; US2005-272194 Applic. Date: 2005-11-10; US20080082396P Applic. Date: 2008-07-21; US20040626792P Applic. Date: 2004-11-10; US20050651288P Applic. Date: 2005-02-09; US20060814706P Applic. Date: 2006-06-16

Inventor: LAHANN JOERG [US]; KAZEMI ABBASS [US]

Title: Compositions Comprising Sulfonated Estolides And Alkyl Ester Sulfonates, Methods Of Making Them, And Compositions And Processes Employing Them

Applicant/Assignee:

Application No.: 12/507011   Filing Date: 21/Jul/2009

Abstract:Compositions comprising sulfo-estolides and alkyl ester sulfonates are described. Detergent formulations, such as laundry detergents, softeners, and other materials, containing any of these materials are disclosed, as well as personal care formulations, hard surface cleaner formulations, and automatic dishwasher detergent formulations. Laundry methods employing these formulations are also disclosed. These formulations are useful as laundry detergents and can be biodegradable, heavy duty liquids, 2x or 3x and up to 6x concentrates, low foaming, and/or effective in a high efficiency washing machine. Methods for laundering fabrics with the compositions are also disclosed.

Priority: WO2009US31455 Applic. Date: 2009-01-20; US20080022662P Applic. Date: 2008-01-22

Inventor: BERNHARDT RANDAL J [US]; ALONSO LOURDES R [US]; DADO GREGORY P [US]; FILIPOVIC EDDIE I [US]; GARIEPY CHRISTOPHER A [US]; MASTERS RONALD A [US]; MURPHY DENNIS S [US]; PYTEL JACQUELINE MAAS [US]; SAJIC BRANKO [US]; SHAPIRO IRENE [US]; WEITGENANT JEREMY AARON [US]

Title: ELASMOBRANCH-REPELLING DOMPOUNDS AND METHODS OF USE

Applicant/Assignee: SHARK DEFENSE L.L.C

Application No.: 11/922065   Filing Date: 12/Jun/2006

Abstract:Compounds for repelling elasmobranch having an aldehyde or derivative, a carboxylic acid a derivative, a ketone or a derivative thereof, a di-ketone or a derivative thereof, a pyridine or derivative thereof, or an antipyrine or a derivative thereof and methods of use thereof.

Priority: US20050689652P Applic. Date: 2005-06-11; US20050750451P Applic. Date: 2005-12-14; WO2006US22912 Applic. Date: 2006-06-12

Inventor: STROUD ERIC MATTHEW [US]

Title: SERIES OF SKIN WHITENING (LIGHTENING) COMPOUNDS

Applicant/Assignee: UNIGEN PHARMACEUTICALS, INC

Application No.: 12/506497   Filing Date: 21/Jul/2009

Abstract:The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

Priority: US20080082422P Applic. Date: 2008-07-21

Inventor: NANDY SANDIP K [US]; LIU JIYUN [US]; NESTEROV ALEXANDRE MIKHAILOVITCH [US]; HERTEL CARMEN [US]; PADMAPRIYA ABEYSINGHE A [US]

Title: PATHOTROPIC TARGETED GENE DELIVERY SYSTEM FOR CANCER AND OTHER DISORDERS

Applicant/Assignee:

Application No.: 12/446976   Filing Date: 05/Nov/2007

Abstract:Systems for pathotropic (disease-seeking) targeted gene delivery are provided, including viral particles with extremely high titers. In particular, the viral particles are engineered to specifically deliver therapeutic or diagnostic agents to a disease site, such as cancer metastic sites. Personalized dosing regimens are also provided to treat diseases such as cancer efficaciously with reduced adverse side effects.

Priority: US2006-055666 Applic. Date: 2006-11-03; WO2007US23305 Applic. Date: 2007-11-05

Inventor: HALL FREDERICK L [US]; LEVY JOHN P [US]; REED REBECCA A [US]; GORDON ERLINDA M [US]

Title: Transdermal Administration of Active Agents, in Particular Diclofenac

Applicant/Assignee: PHARMACODEX LTD

Application No.: 12/086045   Filing Date: 07/Dec/2006

Abstract:The present invention relates to compositions for transdermal administration of therapeutic agents for providing a local and sustained therapeutic effect, wherein the extent of systemic administration can be controlled. In particular, the invention relates to spreadable compositions, or compositions which may be solid at a temperature of about 25 DEG C. or less and have a softening point of not higher than 35 DEG C., for use in the treatment of pain and/or inflammation or administration of a local anaesthetic, wherein transdermal administration of the therapeutic agent may be either rapid or sustained.

Priority: GB20050024958 Applic. Date: 2005-12-07; WO2006GB50434 Applic. Date: 2006-12-07

Inventor: STANIFORTH JOHN [GB]; GOGGOM PAUL [GB]

Title: METHOD FOR PREPARING PARTICLES COMPRISING METAL OXIDE COATING AND PARTICLES WITH METAL OXIDE COATING

Applicant/Assignee: SOL-GEL TECHNOLOGIES LTD

Application No.: 12/525331   Filing Date: 03/Feb/2008

Abstract:The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface

(b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer

(c) repeating step (b) at least 4 more times

and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.

Priority: US20070898700P Applic. Date: 2007-02-01; WO2008IL00141 Applic. Date: 2008-02-03

Inventor: TOLEDANO OFER [IL]; BAR-SIMANTOV HAIM [IL]; BILMAN NISSIM [IL]; SHAPIRO LEORA [IL]; ABU-REZIQ RAED [IL]; SRIADIBHATLA SRIKANTH [US]; SOMMER WILLIAM T [US]

Title: COMPOSITIONS AND METHODS FOR LIGHTENING SKIN AND PROTECTING SKIN FROM ULTRAVIOLET RADIATION WITH GLUTATHIONE

Applicant/Assignee:

Application No.: 12/355666   Filing Date: 16/Jan/2009

Abstract:A glutathione composition for lightening or protecting skin is disclosed together with a method for lightening skin or protecting the skin from the effects of ultraviolet radiation is accomplished by administering glutathione to the skin. The glutathione may be glutathione modified with at least one fatty acid or the glutathione molecule is acetylated/esterified. In instances where it is acetylated/esterified, it may optionally be associated with cyclodextrin.

Priority: US20080022165P Applic. Date: 2008-01-18

Inventor: SKINNER KEITH K [US]

Title: COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE

Applicant/Assignee: ZAMBON S.P.A

Application No.: 12/374828   Filing Date: 13/Jul/2007

Abstract:The present invention relates to odour improved dermatological or cosmetic preparations comprising N-acetylcysteine and a polyol system containing one or more polyols as masking odour agents. The emulsions of the present invention are useful in the treatment of dermatological disorders or cosmetic skin conditions.

Priority: EP20060015440 Applic. Date: 2006-07-25; WO2007EP57271 Applic. Date: 2007-07-13

Inventor: RAMPOLDI LUCA [IT]; MORETTO ALBERTO [IT]; GRASSANO ALESSANDRO [IT]

Title: Active Sunscreen Composition

Applicant/Assignee: RHODE ISLAND HOSPITAL

Application No.: 12/430739   Filing Date: 27/Apr/2009

Abstract:The invention relates to topical compositions comprising a fluorescent dye that absorbs UVA and UVB radiation and converts it into a healing light, in combination with a dermatologically acceptable excipient. The compositions of the invention are useful for repairing photo-damaged skin cells and reducing or preventing future skin damage as a result of exposure to UV light.

Priority: US20080125526P Applic. Date: 2008-04-25

Inventor: JAY GREGORY D [US]; CRAWFORD GREGORY [US]

Title: Compounds, Formulations, and Methods for Ameliorating Telangiectasis

Applicant/Assignee: GALDERMA LABORATORIES INC

Application No.: 12/544663   Filing Date: 20/Aug/2009

Abstract:Methods, compounds, and topical formulations for treatment of telangiectasias are disclosed. The methods comprise topically applying a composition comprising an alpha-adrenergic receptor agonist to telangiectatic skin. Amelioration of telangiectasia symptoms begins within minutes after topical application of a disclosed composition. A single application can significantly lessen telangiectasia discoloration for at least about 2 hours.

Priority: US2006-449079 Applic. Date: 2006-06-08; US2004-853585 Applic. Date: 2004-05-25; US20030473611P Applic. Date: 2003-05-27

Inventor: DEJOVIN JACK A [US]; DEJOVIN ISABELLE JEAN [US]; POWALA CHRISTOPHER [US]

Title: Cosmetic composition with skin tightening effect

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/585755   Filing Date: 24/Sep/2009

Abstract:The present invention relates to a mixture, having a skin-tightening effect, which is made up of: 10 to 80% by Weight of a polysaccharide, preferably of an alginate, having a molecular weight of less than 600,000 Daltons, preferably less than 400,000 Daltons and more preferably less than 200,000 Daltons, 15 to 75% by weight of a polyhydroxylated agent selected from sugars and their derivatives, particularly sugar esters and sugar, ethers, preferably sorbitol, 3 to 15% by Weight of polyvinyl alcohol) or polyvinylpyrrolidone, and 0 to 25% by weight of cellulose or of a derivative of cellulose, such as carboxymethylcellulose or hydroxymethylcellulose. The present invention also relates to cosmetic compositions which contain this mixture. These cosmetic compositions enable a mechanical smoothing of the surface of the skin to be obtained progressively with great comfort of use and enables a good fixing of make-up products.

Priority: FR20010011123 Applic. Date: 2001-08-27; US2004-487693 Applic. Date: 2004-02-26; WO2002FR02941 Applic. Date: 2002-08-27

Inventor: DELAGE-GROUILLER HERVE [FR]; NOE BRIGITTE [FR]; MAHE CHRISTIAN [FR]

Title: EXTERNAL PREPARATION FOR SKIN

Applicant/Assignee:

Application No.: 12/445177   Filing Date: 11/Oct/2007

Abstract:The present invention provides an external preparation for skin comprising a phospholipid having an iodine value of 80 to 110, ethanol in an amount of 55 to 83 wt % and water in an amount of 15 to 43 wt %, which is improved in it's preparation stability by suppressing an increase in an acid value of phospholipid. The present invention also provides an external preparation for skin which is improved in percutaneous absorption of medically effective ingredient(s). The present invention provides further a method for suppressing an increase in an acid value of phospholipid by comprising phospholipid having high iodine value and high concentration of ethanol and water, as well as a method for improving percutaneous absorption of medically effective ingredient(s) in external preparation for skin.

Priority: JP20060279252 Applic. Date: 2006-10-12; WO2007JP69860 Applic. Date: 2007-10-11

Inventor: ABE MASAMICHI [JP]; HARADA AYAKO [JP]; HONMA YOICHI [JP]

Title: BLOCK POLYMER, COSMETIC COMPOSITION COMPRISING IT AND COSMETIC TREATMENT PROCESS

Applicant/Assignee: L'OREAL

Application No.: 12/506328   Filing Date: 21/Jul/2009

Abstract:A block polymer containing, in a block with a Tg greater than 20 DEG C., at least one monomer of formula (I): The invention also relates to a cosmetic composition comprising the block polymer in a cosmetically acceptable medium, and also to a cosmetic process for treating keratin materials using the composition, and most particularly to a process for making up the lips.

Priority: FR20080055070 Applic. Date: 2008-07-24; US20080095034P Applic. Date: 2008-09-08

Inventor: FARCET CELINE [FR]

Title: COSMETIC USE OF ORGANIC RESINATES

Applicant/Assignee: CHANEL PARFUMS BEAUTE

Application No.: 12/531162   Filing Date: 14/Mar/2008

Abstract:A cosmetic method for releasing an active principle in a controlled fashion to uninjured skin, as a function of the ion content in or on skin, by exchange with the ions, in order to provide at least one cosmetic benefit to the skin, the method includes applying onto skin a composition containing, in a cosmetically acceptable medium, at least one resinate including one organic ion-exchange resin and at least one ionizable cosmetic active principle bonded in noncovalent fashion to the resin.

Priority: FR20070001840 Applic. Date: 2007-03-14; US20070941741P Applic. Date: 2007-06-04; WO2008EP53109 Applic. Date: 2008-03-14

Inventor: CASADO-CHAUDANSON AUDREY MARJORIE [FR]; PASTOR AUDREY CELINE MARCELLE [FR]

Title: NEURONAL EXOCYTOSIS INHIBITING PEPTIDES

Applicant/Assignee: LIPOTEC, S.A

Application No.: 12/447136   Filing Date: 24/Oct/2007

Abstract:The invention relates to peptides of general formula (I): R1-AA-R2 (I) which can regulate neuronal exocytosis, their stereoisomers and racemic or non-racemic mixtures thereof, and the cosmetically or pharmaceutically acceptable salts thereof, wherein AA is a sequence of 3 to 40 adjacent amino acids contained in the amino acid sequence of the SNAP-25 protein, R1 is selected from the group consisting of H or alkyl, aryl, aralkyl or acyl group

and R2 is selected from the group consisting of amino, hydroxyl or thiol, substituted or non-substituted with aliphatic or cyclic groups, with the condition that when R1 is H or acetyl, R2 is not non-substituted amino, hydroxyl or thiol. The invention also relates to a method of obtaining such peptides, cosmetic or pharmaceutical compositions containing them and their use to treat those conditions requiring neuronal exocytosis regulation, preferably for treating the skin.

Priority: ES20060002720 Applic. Date: 2006-10-25; WO2007ES00603 Applic. Date: 2007-10-24

Inventor: CARRENO SERRAIMA CRISTINA [ES]; PONSATI OBIOLS BERTA [ES]; VAN DEN NEST WIM [ES]; FERNANDEZ CARNEADO JIMENA [ES]; FERRER MONTIEL ANTONIO [ES]; CEBRIAN PUCHE JUAN [ES]; ALMINANA DOMENECH NURIA [ES]

Title: DISPERSION COMPOSITION, COSMETIC PREPARATION FOR SKIN CARE, AND METHOD FOR PRODUCING DISPERSION COMPOSITION

Applicant/Assignee: FUJIFILM CORPORATION

Application No.: 12/522152   Filing Date: 27/Dec/2007

Abstract:The present invention provides: a dispersion composition including a carotenoid-containing oily component, the dispersion composition being obtained by mixing an aqueous dispersion containing emulsion particles containing the carotenoid-containing oily component and a phospholipid or a derivative thereof with an aqueous composition containing ascorbic acid or a derivative thereof and an oily component that is 20% by mass or less relative to the mass of the whole dispersion composition, and the dispersion composition having emulsion particles having an average particle diameter of 200 nm or less

a dispersion composition including a carotenoid-containing oily component, the dispersion composition being obtained by mixing an aqueous dispersion containing emulsion particles containing a carotenoid-containing oily component and a phospholipid or a derivative thereof with an aqueous composition containing ascorbic acid or a derivative thereof and a pH adjusting agent, and the dispersion composition having a pH value in the range of 5 to 7.5

and a cosmetic preparation for skin care including one or other of the dispersion compositions.

Priority: JP20070000679 Applic. Date: 2007-01-05; JP20070169635 Applic. Date: 2007-06-27; WO2007JP75210 Applic. Date: 2007-12-27

Inventor: KAWABUCHI TATSUO [JP]; KUBO TOSHIAKI [JP]; OGAWA MANABU [JP]; SUZUKI KEIICHI [JP]; TASHIRO TOMOKO [JP]; SUDO YUKIO [JP]

Title: Compositions and Methods for Treating Acne

Applicant/Assignee: REVANCE THERAPEUTICS, INC

Application No.: 11/816670   Filing Date: 30/Mar/2006

Abstract:This invention provides anti-acne kits that are useful for treating acne, especially severe cases of acne. The anti-acne kits include a vasoconstrictor and an anti-acne agent, and optionally one or more of a a skin lightening therapeutic, a sealing layer, a skin cleanser, an astringent, a skin penetration enhancer, a sunscreen, and nutritional supplements that promote healing of acne lesions. This invention also provides methods for treating acne using a vasoconstrictor in conjunction with an anti-acne agent.

Priority: US20050666531P Applic. Date: 2005-03-30; WO2006US12095 Applic. Date: 2006-03-30

Inventor: WAUGH JACOB M [US]; LEE JAE HOON [US]

Title: Novel Derivatives of Cyclic Compound And The Use Thereof

Applicant/Assignee: WONKISOPHARM CO., LTD

Application No.: 12/307153   Filing Date: 02/Jul/2007

Abstract:Disclosed is tonovel cyclic derivatives having potent inhibiting effect on melanin formation and skin hyper-pigmentation activity with no adverse response to skin. They can be used as the therapeutics for treating and preventing the skin disease caused by over-reproduced melanin.

Priority: KR20060062703 Applic. Date: 2006-07-04; WO2007KR03199 Applic. Date: 2007-07-02

Inventor: CHO HYUN CHUL [KR]; CHOI YONGHYUN [KR]; YHEI JONGHAN [KR]

Title: ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME

Applicant/Assignee: H. LUNDBECK A/S

Application No.: 12/504711   Filing Date: 17/Jul/2009

Abstract:The present invention provides adamantyl-diamide derivatives of formula (1): wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof

and pharmaceutical compositions and methods using the same.

Priority: US20090160804P Applic. Date: 2009-03-17; US20080083563P Applic. Date: 2008-07-25

Inventor: JIMENENZ HERMOGENES N [US]; LI GUIYING [US]; DOLLER DARIO [US]; GRENON MICHEL [US]; WHITE ANDREW D [US]; MA GIL [US]; GUO MAOJUN [CN]

Title: Dermatological/cosmetic compositions comprising a retinoid and benzoyl peroxide

Applicant/Assignee: GALDERMA RESEARCH & DEVELOPMENT

Application No.: 12/318938   Filing Date: 13/Jan/2009

Abstract:Dermatological/cosmetic compositions contain, in a physiologically acceptable medium, at least one retinoid, dispersed benzoyl peroxide and a gelling system comprising at least two categories of compounds.

Priority: FR20060052967 Applic. Date: 2006-07-13; WO2007EP57091 Applic. Date: 2007-07-11

Inventor: LOUIS FABIENNE [FR]; WILLCOX NATHALIE [FR]; SEGURA-ORSONI SANDRINE [FR]

Title: ANTIMICROBIAL COMPOSITIONS

Applicant/Assignee:

Application No.: 12/445376   Filing Date: 25/Oct/2007

Abstract:Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water

a cationic antimicrobial agent such as chlorhexidine gluconate

a fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof

and optionally an emollient ester such as diesters of bibasic acids and triesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

Priority: US20060863335P Applic. Date: 2006-10-27; WO2007US82465 Applic. Date: 2007-10-25

Inventor: ASMUS ROBERT A [US]; HOBBS TERRY R [US]

Title: Treatment of faecal incontinence and other conditions with 1R, 2S-methoxamine

Applicant/Assignee: NORGINE EUROPE BV

Application No.: 12/586973   Filing Date: 30/Sep/2009

Abstract:1R,2S-Methoxamine may be used topically for effective treatment of faecal incontinence at low doses without local or systemic side effects, for example, without affecting blood pressure. 1R,2S-Methoxamine may be used to treat other disturbances and disorders of the gastrointestinal, as a pressor agent, as a nasal decongestant and in ophthalmology, at low does and without significant side effects.

Priority: GB20010030763 Applic. Date: 2001-12-21; WO2002GB05864 Applic. Date: 2002-12-20; US2004-499873 Applic. Date: 2004-12-27

Inventor: BARRAS NORMAN [GB]; THOMPSON JEFFREY MARTIN [GB]

Title: SUPERTHIN WOUND DRESSING HAVING FOLDED RELEASE SHEET

Applicant/Assignee: JENTEC , INC

Application No.: 12/302695   Filing Date: 21/Jun/2007

Abstract:A wound dressing, which is easy to apply in very few steps, the dressing having a thin film section surrounded by a thicker outside border section. The border section provides rigidity to the dressing by virtue of being thicker than the inner thin film portion of the dressing. The wound dressing has a film on one side of the dressing layer and a release sheet on a skin-contacting side of the dressing layer.

Priority: US20060816295P Applic. Date: 2006-06-23; WO2007US71736 Applic. Date: 2007-06-21

Inventor: DEWEY JAMES C [US]

Title: Method and process for producing youthful-appearing, small-pored, and smooth skin

Applicant/Assignee:

Application No.: 10/735362   Filing Date: 12/Dec/2003

Abstract:The method and process for producing youthful appearing, small-pored, and smooth skin comprises pre-treating the skin topically with retinoic acid, applying a contaminant in oil to the skin, and removing the contaminate by exploding or rupturing it with laser light. When treating the face, removing the contaminant requires only about 4 minutes. The laser light itself does not injure the skin but the rupture of the contaminant produces thermal injury in the high dermis leaving the epidermis intact. Repeated intermittent laser treatments and applications of topical retinoic acid produces the desired results in the skin indefinitely as long as the treatment and applications are continued.

Priority: US2002-047335 Applic. Date: 2002-01-14

Inventor: PARSONS DIANA J [US]

Title: SKIN REJUVINATION RESURFACING DEVICE AND METHOD OF USE

Applicant/Assignee: SPAMEDICA INTERNATIONAL SRL

Application No.: 12/573923   Filing Date: 06/Oct/2009

Abstract:A skin rejuvenation resurfacing apparatus comprising an oscillating, reciprocating high speed, needle-based device and its related procedure for inducing mechanical trauma to an area of the skin to be treated.

Priority: US2005-315841 Applic. Date: 2005-12-22; US2009-555914 Applic. Date: 2009-09-09

Inventor: MULHOLLAND R STEPHEN [CA]

Title: URETHANE COMPOUND COMPRISING AN INCORPORATED POLYETHER GROUP-CONTAINING SILICONE DERIVATIVE AND A NITROGEN HETEROCYCLE

Applicant/Assignee: BASF AKTIENGESELLSCHAFT

Application No.: 11/722189   Filing Date: 22/Dec/2005

Abstract:The present invention relates to a urethane compound which comprises, in incorporated form, at least one polyether group-containing silicone derivative, at least one nitrogen heterocycle and at least one polyisocyanate, to cosmetic and pharmaceutical compositions which comprise such a urethane compound, and to the use of such a urethane compound.

Priority: DE200410062201 Applic. Date: 2004-12-23; WO2005EP13927 Applic. Date: 2005-12-22

Inventor: NGUYEN-KIM SON [DE]

Title: SUNSCREEN COMPOSITIONS

Applicant/Assignee:

Application No.: 12/449932   Filing Date: 05/May/2007

Abstract:Sunscreen and sunblock formulations that provide cytoprotective and immuno-enhancing additives avoiding endocrine disrupting agents, (a) at least one inorganic sun-blocking or sunscreen agent that is a proven non-endocrine disrupter, (b) at least one emollient proven to be a non-endocrine disrupter

and (c) an oil component capable of protecting skin from harmful effects of radiation including sunlight and ultraviolet light wherein the oil is a carrier oil, an essential oil, or both are described. The formulations preferably include an essential oil of a naturally-occurring substance as well as suitable inorganic components including titanium dioxide, zinc oxide, silica or silicon dioxide, fluoropolymers, and mixtures thereof. Suitable organic components include butylmethoxy dibenzoylmethane. Cold-processed Aloe barbadensis Miller-Stockton, a single species of Aloe barbadensis containing glucose-rich mannose-containing oligosaccharide or oligosaccharides, can also be used. Test methodologies and results indicate specific differences from conventional formulations.

Priority: WO2007US05672 Applic. Date: 2007-03-05

Inventor: GRUNE GUERRY L [US]

Title: COMPOSITION CONTAINING A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND COSMETIC TREATMENT PROCESS

Applicant/Assignee: L'OREAL

Application No.: 12/495875   Filing Date: 01/Jul/2009

Abstract:Composition containing, in a cosmetically or dermatologically acceptable medium, a compound that may be obtained by reaction between: an oil bearing at least one nucleophilic and/or electrophilic reactive function, and a junction group capable of establishing hydrogen bonds with one or more partner junction groups, the junction group bearing at least one reactive function capable of reacting with the reactive function borne by the oil, and also comprising at least one unit of formula (I) or (II):

Priority: FR20080054556 Applic. Date: 2008-07-04; US20080080283P Applic. Date: 2008-07-14

Inventor: CHODOROWSKI-KIMMES SANDRINE [FR]; RODRIGUEZ IVAN [FR]

Title: USE OF CHROMAN-4-ONE DERIVATIVES

Applicant/Assignee: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG

Application No.: 12/531369   Filing Date: 21/Feb/2008

Abstract:The invention relates to the use of compounds of the formula (I) or of a composition comprising at least one compound of the formula (I), containing radicals as described in the claims, for the care, preservation or improvement of the general state of the skin or hair.

Priority: DE200710013366 Applic. Date: 2007-03-16; WO2008EP01352 Applic. Date: 2008-02-21

Inventor: CAROLA CHRISTOPHE [DE]; ROSSKOPF RALF [DE]

Title: MALODOR COUNTERACTING COMPOSITIONS AND METHOD FOR THEIR USE

Applicant/Assignee: FIRMENICH SA

Application No.: 12/438713   Filing Date: 24/Aug/2007

Abstract:The invention relates to a malodor counteractancy or counteracting (MOC) method that resorts to the use of specific malodor counteracting (MOC) mixtures of fragrance ingredients. More particularly, the invention relates to new MOC compositions capable of neutralizing or masking in an efficient manner malodors of a large variety of such as body or animal malodors, kitchen malodors, toilet and bathroom malodors, and tobacco malodor. The novel MOC compositions of the invention contain at least one nitrile material in combination with another fragrance material and can be used in any finished consumer products such as air fresheners, kitchen or toilet/bathroom cleaning or freshening products, textile treatment products and products for application on the human skin or hair, or on animal fur, litter containers or cages.

Priority: EP20060119640 Applic. Date: 2006-08-28; WO2007IB53399 Applic. Date: 2007-08-24

Inventor: TRANZEAT LYSE [GB]; O'LEARY NICHOLAS [US]; KOS WESSEL-JAN [GB]

Title: Skin Repair Compositions Comprising Circadian Gene Activators And A Synergistic Combination Of Sirt1 Gene Activators

Applicant/Assignee:

Application No.: 12/489619   Filing Date: 23/Jun/2009

Abstract:Compositions and methods for enhancing repair of damaged DNA in skin cells. Topical compositions comprising at least one agent that upregulates circadian gene expression in skin cells and at least one non-circadian agent that delays mitosis in skin cells. Preferably, such compositions comprise one or more keratinocyte clock and per1 gene activators, along with SIRT1 or one or more sirt1 activators. More preferably, the sirt1 activator is a synergistic combination of specific peptidic sirt1 activators and resveratrol. Preferably, such compositions are easy to use, efficacious, cosmetically acceptable, chemically, thermodynamically and light stable, safe for topical use, have little or no side effects, and commercially feasible in a personal care marketplace.

Priority: US2007-837658 Applic. Date: 2007-08-13; US2009-367705 Applic. Date: 2009-02-09

Inventor: MAES DANIEL H [US]; PERNODET NADINE A [US]; MAMMONE THOMAS [US]; PELLE EDWARD [US]; COLLINS DONALD F [US]; SLUTSKY LENNY [US]; GOLDGRABEN KERRI [US]; MCCARTHY JAMES TIMOTHY [US]

Title: Cosmetics Comprising A Modified Organopolysiloxane

Applicant/Assignee:

Application No.: 11/993436   Filing Date: 21/Jun/2006

Abstract:This invention relates to a cosmetics characterized in that it contains a gelling agent comprising an organopolysiloxane having a silicon-bonded organic group represented by general formula:R1-X-CO-NH-[X-N(-CO-X-R1)]p-X- (1) (wherein R1 designates a group containing metal salt of a carboxylic acid represented by formula -COO- (Mn+)1/n, (where M is a metal that has a valence of 1 or higher)

X's designate the same or different C2 to C14 bivalent hydrocarbon groups

and p designates an integer from 0 to 10.). Preferably, the organosiloxane has an optionally substituted C9 or more univalent hydrocarbon group. Adding the gelling agent makes it possible to provide a cosmetic possessing superior temporal stability, water retention properties, sensory feel, gloss, curl retention, and cleansing power.

Priority: JP20050180066 Applic. Date: 2005-06-21; JP20050180072 Applic. Date: 2005-06-21; JP20060166880 Applic. Date: 2006-06-16; WO2006JP312848 Applic. Date: 2006-06-21

Inventor: OKAWA TADASHI [JP]; IIMURA TOMOHIRO [JP]

Title: Personal Care Article

Applicant/Assignee:

Application No.: 12/226118   Filing Date: 05/Apr/2007

Abstract:A personal care article including a substrate having impregnated therein, applied thereon or arranged to substantially encase, a cosmetic composition which includes a hair modification active, wherein the pH of the composition is substantially less than 9.0, and at least a portion of the article has exfoliating properties.

Priority: GB20060006992 Applic. Date: 2006-04-07; GB20060012486 Applic. Date: 2006-06-23; WO2007GB01305 Applic. Date: 2007-04-05

Inventor: CAWTHORNE LEE [GB]; DODD KAREN [GB]; TINDAL ANNE [GB]

Title: Use of Polymers

Applicant/Assignee: CROMA-PHARMA GESELLSCHAFT M.B.H

Application No.: 12/520820   Filing Date: 21/Dec/2007

Abstract:The present invention relates to the use of a thiol-group-containing polymer for preparing an implant for tissue augmentation, wherein the basis polymer is a polysaccharide.

Priority: AT20060002136 Applic. Date: 2006-12-22; US20060871534P Applic. Date: 2006-12-22; WO2007AT00585 Applic. Date: 2007-12-21

Inventor: HORNOF MARGIT [AT]

Title: MILD COMPOSITION FOR SKIN DISINFECTION

Applicant/Assignee: ASEPTIX RESEARCH B.V

Application No.: 12/312874   Filing Date: 12/Dec/2007

Abstract:The present invention discloses compositions for aqueous skin disinfection comprising hydrogen peroxide in a concentration of at least 0.1% to 10% (w/w), preferably 0.2-6%, and an N-acylated amino acid and/or peptide in the range of 0.1-20% (w/w), preferably 0.1-10%, more preferably 0.2-8%, and most preferably 0.2-5% (w/w). The N-acylated amino acid composition may be N-acylated glutamic acid and/or an N-acylated wheat protein hydro-lysate, or a salt thereof.

Priority: EP20060126044 Applic. Date: 2006-12-13; WO2007EP63831 Applic. Date: 2007-12-12

Inventor: BOBBERT ILJA [NL]

Title: EXTRACT OF STEWARTIA KOREANA AND USE THEREOF

Applicant/Assignee: RNA, INC

Application No.: 12/279194   Filing Date: 13/Feb/2007

Abstract:The present invention relates to an extract of Stewartia koreana and use thereof. More particularly, it relates to an extract of Stewartia koreana which is extracted with any one selected from the group consisting of water, a C1-4 low alcohol, a polar solvent, a non-polar solvent and a mixture thereof, and a pharmaceutical composition for promoting angiogenesis or tissue regeneration and a cosmetic for improving wrinkles comprising the same as an effective ingredient. The extract of Stewartia koreana according to the present invention promotes migration and multiplication of endothelial cell and shows excellent effect in angiogenesis and wound healing and thus, is useful in treatment or prevention of diseases which requires angiogenesis for healing of wounded and frostbitten region, wound healing after surgical operation, and treatment and prevention of gastric ulcer, ischaemic heart diseases and hair loss. Also, the extract shows the dermal tissue regenerating effect and thus, is useful as a cosmetic for improving wrinkles.

Priority: KR20060013888 Applic. Date: 2006-02-13; WO2007KR00763 Applic. Date: 2007-02-13

Inventor: KIM JI YOUNG [KR]; CHUNG DAE KYUN [KR]; LEE TAE HOON [KR]; LEE GUY WILHEM [KR]; LEE JUNG MIN [KR]

Title: Absorbent Article With Barrier Component

Applicant/Assignee: THE PROCTER & GAMBLE COMPANY

Application No.: 12/535271   Filing Date: 04/Aug/2009

Abstract:An absorbent article may comprise a barrier component, the barrier component may comprise a nonwoven barrier sheet, the nonwoven barrier sheet may comprise a spunbond nonwoven web comprising spunbond fibers, and the nonwoven barrier sheet may further comprise a meltblown nonwoven web comprising meltblown fibers. The spunbond fibers may have a number average fiber diameter of from about 6 to about 18 microns. The meltblown fibers may have a number average fiber diameter from about 1 to about 5 microns. And, the total weight percentage (by basis weight of the nonwoven barrier sheet) of the meltblown web may be from about 5% to about 30%.

Priority: US20080085903P Applic. Date: 2008-08-04

Inventor: REICHARDT NICOLE ANJA [DE]; SPRINGOB CHRISTIAN [DE]; WISE BRANDON ELLIS [US]; HUMMELGAARD LONE KONDRUP [DK]; UDENGAARD BRIAN [DK]

Title: DELIVERY PARTICLE

Applicant/Assignee: APPLETON PAPERS INC. (A DELAWARE CORPORATION)

Application No.: 12/508214   Filing Date: 23/Jul/2009

Abstract:The present application relates to encapsulated benefit agents, compositions comprising such encapsulated benefit agents and processes for making and using compositions comprising such encapsulated benefit agents that do not require or require a reduced amount of scavenger materials. Such encapsulated benefit agents, compositions comprising such encapsulated benefit agents are processed such that no or lower levels of scavenger materials are required.

Priority: US20080084786P Applic. Date: 2008-07-30

Inventor: DIHORA JITEN ODHAVJI [US]; VANDERVEKEN WALTER FRANCISCUS JOANNA [BE]; KIRKSEY JR SANFORD THEODORE [US]; DEBRAAL JOHN CHARLES [US]; BOBNOCK ROBERT STANLEY [US]; DRUCKREY ADAM KEITH [US]; HART GARY THOMAS [US]

Title: DELIVERY PARTICLE

Applicant/Assignee:

Application No.: 12/507814   Filing Date: 23/Jul/2009

Abstract:The present application relates to encapsulated benefit agents, compositions comprising such encapsulated benefit agents and processes for making and using compositions comprising such encapsulated benefit agents that do not require or require a reduced amount of scavenger materials. Such encapsulated benefit agents, compositions comprising such encapsulated benefit agents are processed such that no or lower levels of scavenger materials are required.

Priority: US20080084786P Applic. Date: 2008-07-30

Inventor: DIHORA JITEN ODHAVJI [US]; VANDERVEKEN WALTER FRANCISCUS [BE]; KIRKSEY JR SANFORD THEODORE [US]; DEBRAAL JOHN CHARLES [US]; BOBNOCK ROBERT STANLEY [US]; HART GARY THOMAS [US]; DRUCKREY ADAM KEITH [US]

Title: Microfluidic Device for Controlled Aggregation of Spider Silk

Applicant/Assignee: TECHNISCHE UNIVERSITAET MUENCHEN

Application No.: 12/227498   Filing Date: 21/May/2007

Abstract:The present invention is directed to a device and method of controlling the phase separation of one or a mixture of two or more spider silk proteins, leading to the defined and controllable assembly of the said silk protein(s) to defined morphologies, such as spheres, nano fibrils, threads, etc.

Priority: EP20060011841 Applic. Date: 2006-06-08; WO2007EP54878 Applic. Date: 2007-05-21

Inventor: SCHEIBEL THOMAS [DE]

Title: NOVEL PROCESS OF SOLUBILIZING PROTEIN FROM A PROTEINACEOUS MATERIAL AND COMPOSITIONS THEREOF

Applicant/Assignee: BIOVA, L.L.C

Application No.: 12/508750   Filing Date: 24/Jul/2009

Abstract:The process for solubilizing proteinaceous material of the present invention includes subjecting the proteinaceous material to a sufficient amount of a basic solution to obtain a supernatant that has a basic pH and exposing the supernatant to the basic solution for a sufficient length of time and temperature for hydrolysis to occur. The process also includes cooling the mixture of the supernatant and proteinaceous material and optionally acidifying the mixture. This process may also include recovering the solubilized protein from the supernatant for use in various applications. Also provided herein is a composition of solubilized proteins from eggshell membrane obtained using processes of the present invention.

Priority: US2008-253719 Applic. Date: 2008-10-17; US20070980607P Applic. Date: 2007-10-17

Inventor: STROHBEHN RONALD E [US]; ETZEL LISA R [US]; FIGGINS JESSE [US]

Title: PROCESS FOR OBTAINING AN ACTIVE INGREDIENT WITH AN IMMEDIATE TENSOR EFFECT ON THE SKIN, ACTIVE INGREDIENT AND COMPOSITIONS

Applicant/Assignee: SOCIETE INDUSTRIELLE LIMOUSINE D'APPLICATION BIOLOGIQUE, DITE SILAB

Application No.: 12/442441   Filing Date: 21/Sep/2007

Abstract:The invention relates to a method for obtaining an active ingredient having an immediate anti-wrinkle and skin-tensioning effect, characterised in that it comprises extracting and purifying high molecular weight polysaccharides from oat bran and/or fibres and/or grains, and solutioning and stabilising the polysaccharides in water. The invention also relates to the product thus obtained, to uses thereof, and to cosmetic compositions containing this active ingredient.

Priority: FR20060053903 Applic. Date: 2006-09-22; FR20070053714 Applic. Date: 2007-03-08; WO2007FR51992 Applic. Date: 2007-09-21

Inventor: PAUFIQUE JEAN [FR]

Title: Administration of fluocinolone acetonide, tretinoin and hydroquinone cream in melasma maintenance therapy

Applicant/Assignee: GALDERMA S.A

Application No.: 12/457732   Filing Date: 19/Jun/2009

Abstract:Topical application of a triple combination immixture of fluocinolone acetonide, tretinoin and hydroquinone is useful for the maintenance therapy of melasma to prevent hyperpigmentation recurrence or reduce the severity of the hyperpigmentation recurrence.

Priority: WO2007EP64269 Applic. Date: 2007-12-19; US20060875529P Applic. Date: 2006-12-19

Inventor: ARELLANO MENDOZA IVONNE [MX]

Title: LOW-DOSE MOMETASONE FORMULATIONS

Applicant/Assignee: PERRIGO ISRAEL PHARMACEUTICALS LTD

Application No.: 12/535406   Filing Date: 04/Aug/2009

Abstract:Provided is a topical cream composition for the delivery of mometasone furoate comprising low dose mometasone furoate for the treatment of corticosteroid responsive dermatoses. The composition of the present invention can be safely applied over large surface areas of the skin (including areas with wrinkles and/or hair), and can be used therapeutically for extended periods of time (e.g., greater than 3 weeks). Treatment with the composition of the present invention carries reduced and/or fewer side effects compared with commercially available mometasone furoate cream products. The cream composition of the present invention is safe for the use of babies and infants under 2 years old. Additionally provided are methods of preparing and using the composition of the invention.

Priority: WO2008IL00485 Applic. Date: 2008-04-09; US20070911185P Applic. Date: 2007-04-11

Inventor: ARKIN MOSHE [IL]; ZEEVI AMIRA [IL]; CHERKEZ STEPHEN [IL]; ASCULAI EILON [IL]; UZAN RINA [IL]; BRAGHINSKI BELLA [IL]

Title: COMPOSITIONS AND METHODS FOR MODULATING CELLULAR MEMBRANE-MEDIATED INTRACELLULAR SIGNAL TRANSDUCTION

Applicant/Assignee: REVALESIO CORPORATION

Application No.: 12/435262   Filing Date: 04/May/2009

Abstract:Provided are electrokinetically-altered fluids (e.g., gas-enriched (e.g., oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide, upon contact with a cell, modulation of at least one of cellular membrane potential and cellular membrane conductivity. Particular aspects of the present invention provide compositions and methods suitable for modulation of at least one of cellular membrane potential and cellular membrane conductivity. Additional aspects provide compositions and methods suitable for modulating intracellular signal transduction, including modulation of at least one of membrane structure, membrane potential or membrane conductivity, membrane proteins or receptors, ion channels, and calcium dependant cellular messaging systems, comprising use of the inventive electrokinetically altered solutions to impart electrochemical and/or conformational changes in membranous structures (e.g., membrane proteins, receptors and/or other components) including G-protein coupled receptors (GPCRs), G-proteins, and/or intracellular junctions (e.g., tight junctions, gap junctions, zona adherins and desmasomes).

Priority: US2008-256774 Applic. Date: 2008-10-23; US20070982719P Applic. Date: 2007-10-25; US20070982720P Applic. Date: 2007-10-25; US20080048332P Applic. Date: 2008-04-28; US20080048340P Applic. Date: 2008-04-28; US20080048347P Applic. Date: 2008-04-28; US20080048404P Applic. Date: 2008-04-28

Inventor: WATSON RICHARD L [US]; WOOD ANTHONY B [US]; ARCHAMBEAU GREGORY J [US]

Title: Blends Comprising a Substituted Fatty Acid or a Derivative Thereof

Applicant/Assignee:

Application No.: 12/508635   Filing Date: 24/Jul/2009

Abstract:The invention concerns blends of a hydroquinone substituted poly unsaturated fatty acid (as present in Kombo nut oil) or a derivative thereof, which blends comprised: (i) 0.1-99.9 wt % of the substituted acid (ii) 0-99.8 wt % of Kombo butter glycerides (iii) 0.1-99.9 wt % of other triglycerides Food products and food supplements comprising such hydroquinone substituted acids are also part of the invention. The substituted acids display many useful health benefits.

Priority: EP20010307523 Applic. Date: 2001-09-04; EP20020251500 Applic. Date: 2002-03-04; US2002-230352 Applic. Date: 2002-08-29

Inventor: BARCLAY SCOTT SINCLAIR [GB]; BOSLEY JOHN ANTHONY [GB]; CAIN FREDERICK WILLIAM [NL]; KOENEN CLAUDIA [NL]; ROGERS JULIA SARAH [GB]; SCHMID ULRIKE [NL]

Title: NAPHTHOQUINONE COMPOSITIONS WITH ANTI-AGING, ANTI-INFLAMMATORY AND SKIN EVEN-TONING PROPERTIES

Applicant/Assignee:

Application No.: 12/499051   Filing Date: 07/Jul/2009

Abstract:The present invention relates to methods and compositions comprising naphthoquinones such as 2,3-dimethylnaphthalene-1,4-dione, for the use of treating, regulating or preventing a skin condition characterized by oxidative stress or a degenerative process. Methods of preventing, lightening or reducing the appearance of visible and/or tactile discontinuities of the skin resulting from skin pigmentation or skin aging are also disclosed.

Priority: US20080137415P Applic. Date: 2008-07-30

Inventor: HINMAN ANDREW W [US]; MILLER GUY M [US]

Title: Methods of Treating Wrinkles, Developing Wrinkle Treatments And Evaluating Treatment Efficacy, Based On Newly Discovered Similarities Between Wrinkles And Skin Wounds

Applicant/Assignee:

Application No.: 12/500374   Filing Date: 09/Jul/2009

Abstract:Disclosed are methods of measuring an endogenous wrinkle electric field and methods of characterizing topical applications, or other treatments, in terms of their effect on the endogenous electric field of wrinkles. Also included, are methods of developing topical applications, or other treatments that have a desired effect on the endogenous electric field of a wrinkle. The methods disclosed herein, are based on a new model of wrinkle physiology that exploits previously unknown similarities between skin wounds and wrinkles.

Priority: US20080085213P Applic. Date: 2008-07-31

Inventor: MAMMONE THOMAS [US]; IONITA-MANZATU VASILE [US]; HAWKINS GEOFFREY [US]; REIN GLEN [US]

Title: DERMAL PATCH

Applicant/Assignee: POWER PAPER LTD

Application No.: 12/575630   Filing Date: 08/Oct/2009

Abstract:The invention is generally directed to a kit and patch for transdermal or intradermal delivery of at least one substance into the skin. The kit includes a dermal patch having an electrochemical cell with two electrodes and a retainer for retaining a conductive fluid which further includes an active substance. The conductive fluid can be deposited on at least one of the two electrodes. Alternatively, the conductive fluid can be applied topically to the skin.

Priority: US2004-757414 Applic. Date: 2004-01-15; WO2002IL00848 Applic. Date: 2002-10-23; US20010330526P Applic. Date: 2001-10-24

Inventor: NITZAN ZVI [IL]; GROSS YOSSI [IL]; MAVOR DANIELA [IL]; TAMARKIN DOV [IL]

Title: Physician's practice aesthetic care program

Applicant/Assignee:

Application No.: 12/221562   Filing Date: 04/Aug/2008

Abstract:Disclosed is a method of generating a revenue stream by providing cosmetic medical aesthetic treatments to patients within their personal medical doctor's or other physician's (PMD's) office such that a second party business entity can provide sourcing of resources required, equipment, software, personnel hiring, operational and clinical training and consulting, development, placement and management of advertising and marketing, and a lead management system for the PMD or group of PMDs. The combining of similarly contracted physicians into an advertising and marketing group is also part of the present disclosure. Another important aspect of the disclosure is that the methods include providing a revenue sharing program between PMDs.

Priority:

Inventor: JONES DENNIS R [US]; NOON THOMAS R [US]

Title: MULTIPLE CONFIGURATION SHOWER DEVICE

Applicant/Assignee:

Application No.: 12/293641   Filing Date: 27/Mar/2007

Abstract:A multiple configuration shower device includes at least one handle (2) connected to a flexible duct for supplying water and at least one water dispensing element (5). The dispensing element (5) is provided with a plurality of water ejection faces (5a, 5b, 5c, 5d), each provided with respective nozzles (U), and comprising at least one connector (6), provided between the handle (2) and the dispensing element (5), which is adapted to allow the manual rotation of the dispensing element (5) about at least one axis which is substantially perpendicular to the handle (2), so as to arrange selectively at least one of the ejection faces (5a, 5b, 5c, 5d) substantially in the direction of the user.

Priority: IT2006BO00219 Applic. Date: 2006-03-30; IT2006BO00220 Applic. Date: 2006-03-30; WO2007IB00818 Applic. Date: 2007-03-27

Inventor: RIGHINI GIUSEPPE [IT]

Title: Peptides Modified with Triterpenoids and Small Organic Molecules: Synthesis and use in Cosmeceuticals

Applicant/Assignee:

Application No.: 11/835165   Filing Date: 07/Aug/2007

Abstract:The present invention relates to the Synthesis of Triterpenoid peptides and mechanism of action for Anti ageing and skin care. The present invention is directed towards anti-aging skin care compositions comprising peptides which are made by linking herbal actives to a pentapeptide for enhanced anti ageing activity by regenerating the dermal matrix. In detail, the present invention relates to the synthesis of Triterpenoid peptides, providing an enhanced and synergistic activity for reducing the consequences of ageing such as appearance of fine expression lines and wrinkles on the skin by cosmetic modes of application. The Triterpenoid peptides of the present invention with its novel dual action mode can be used for skin ageing & collagen insufficiency. Its Triterpenoid group acts by preventing oxidation and excess activity of serine proteases like elastase and collagenase that result in wrinkling of skin. With added peptides which boost the collagen and other matrix protein, Triterpenoid peptides provide a complete protection against pre mature ageing and functions as a best anti ageing ingredient.

Priority:

Inventor: MAJEED MUHAMMED [US]; CHANDRAMOULI RENUKESHWAR H [IN]; NAGABHUSHANAM KALYANAM [US]; SOOD RATTAN [IN]; PRAKASH SUBBALAKSHMI [US]; ANAND SUSMITHA [IN]

Title: PERSONAL CARE AND COSMETICS COMPOSITIONS COMPRISING BIOLOGICALLY-BASED MONO AND DI ESTERS

Applicant/Assignee:

Application No.: 12/579538   Filing Date: 15/Oct/2009

Abstract:Personal care compositions comprising esters of 1,3-propanediol and acceptable carriers are provided. The esters can have at least 3% biobased carbon, and the compositions can further comprise 1,3-propanediol that is biologically-derived. Also provided are processes for producing personal care compositions comprising esters of 1,3-propanediol and acceptable carriers. The processes comprise providing biologically produced 1,3-propanediol, contacting the 1,3-propanediol with organic acids, which produces the esters, recovering the esters, and incorporating the esters into personal care formulations. Also provided are processes of making a personal care composition comprising providing an ester of 1,3 propanediol and mixing the ester with an acceptable carrier to form a personal care composition.

Priority: US2007-705227 Applic. Date: 2007-02-12; US20060772471P Applic. Date: 2006-02-10; US20060772194P Applic. Date: 2006-02-10; US20060772193P Applic. Date: 2006-02-10; US20060772111P Applic. Date: 2006-02-10; US20060772120P Applic. Date: 2006-02-10; US20060772110P Applic. Date: 2006-02-10; US20060772112P Applic. Date: 2006-02-10; US20060846948P Applic. Date: 2006-09-25; US20060853920P Applic. Date: 2006-10-24; US20060859264P Applic. Date: 2006-11-15; US20060872705P Applic. Date: 2006-12-04; US20070880824P Applic. Date: 2007-01-17

Inventor: FENYVESI GYORGYI [US]; WEHNER ANN [US]; JOERGER MELISSA [US]; POLADI RAJA HARI PRASAD R [US]

Title: Skin Lightening Composition Comprising CO2 Extracts

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 12/185885   Filing Date: 05/Aug/2008

Abstract:Skin lightening additives and skin lightening compositions with carbon dioxide obtained plant extracts are described. The compositions are suitable for topical application and may comprise CO2 obtained Chamomile extract.

Priority:

Inventor: MADISON STEPHEN ALAN [US]

Title: Method for Preparing a Lipophilic Vine Extract

Applicant/Assignee:

Application No.: 12/460742   Filing Date: 23/Jul/2009

Abstract:The present invention relates to a method for preparing a lipophilic extract from lignified portions of vine, such as shoots, stock and roots, characterized in that said method comprises a step for extraction from said lignified portions with an apolar solvent

to an extract obtained by such a method

to the use of such an extract as an excipient in a cosmetic composition

and to a cosmetic composition comprising such an extract.

Priority: FR20080055117 Applic. Date: 2008-07-25

Inventor: PECHER VIRGINIE [FR]; ANDRE PATRICE [FR]

Title: PYRIMIDINE DERIVATIVES FOR THE PREVENTION OF HIV INFECTION

Applicant/Assignee:

Application No.: 12/567051   Filing Date: 25/Sep/2009

Abstract:This invention concerns the use of a compound for the manufacture of a medicament for the prevention of HIV infection via sexual intercourse and related intimate contact between partners, wherein the compound is a compound of formula a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein the ring containing -a1=a2-a3=a4- and -b1=b2-b3=b4- represents phenyl, pyridyl, pyrimidinyl, pirazinyl, pyridazinyl

n is 0 to 5

m is 1 to 4

R1 is hydrogen

aryl

formyl

C1-6alkylcarbonyl

C1-6alkyl

C1-6alkyloxycarbonyl

substituted C1-6alkyl, C1-6alkylcarbonyl, C1-6alkyloxycarbonyl, C1-6alkylcarbonyloxy

substituted C1-6alkyloxyC1-6alkylcarbonyl

R2 is hydroxy, halo, optionally substituted C1-6alkyl, C3-7cycloalkyl, optionally substituted C2-6alkenyl, optionally substituted C2-6alkynyl, C1-6alkyloxy, C1-6alkyloxycarbonyl, carboxyl, cyano, nitro, amino, mono- or di(C1-6alkyl)amino, polyhalomethyl, polyhalomethyloxy, polyhalomethylthio, -S(-O)pR6, -NH-S(-O)pR6, -C(-O)R6, -NHC(-O)H, -C(-O)NHNH2, -NHC(-O)R6, -C(-NH)R6 or a 5-membered heterocycle

X1 is -NR5-, -NH-NH-, -N-N-, -O-, -C(-O)-, C1-4alkanediyl, -CHOH-, -S-, -S(-O)p-, -X2-C1-4alkanediyl- or -C1-4alkanediyl-X2-

R3 is NHR13

NR13R14

-C(-O)-NHR13

-C(-O)-NR13R14

-C(-O)-R15

-CH-N-NH-C(-O)-R16

substituted C1-6alkyl

optionally substituted C1-6alkyloxyC1-6alkyl

substituted C2-6alkenyl

substituted C2-6alkynyl

C1-6alkyl substituted with hydroxy and a second substituent

-C(-N-O-R8)-C1-4alkyl

R7

or -X3-R7

R4 is halo, hydroxy, C1-6alkyl, C3-7cycloalkyl, C1-6alkyloxy, cyano, nitro, polyhaloC1-6alkyl, polyhaloC1-6alkyloxy, aminocarbonyl, C1-6alkyloxycarbonyl, C1-6alkylcarbonyl, formyl, amino, mono- or di(C1-4alkyl)amino

and pharmaceutical compositions comprising them.

Priority: WO2003EP01291 Applic. Date: 2003-02-07; US2004-544735 Applic. Date: 2004-02-04; WO2004EP01011 Applic. Date: 2004-02-04

Inventor: HEERES JAN [BE]; LEWI PAULUS JOANNES [BE]; JANSSEN PAUL ADRIAAN JAN [BE]; ARTS FRANK XAVIER JOZEF HERWIG [BE]; DE JONGE MARC RENE [NL]; KOYMANS LUCIEN MARIA HENRICUS [BE]; DAEYAERT FREDERIK FRANS DESIRE [BE]; VINKERS HENDRIK MAARTEN [BE]; GULLEMONT JEROME EMILE GEORGES [FR]; PASQUIER ELISABETH THERESA JEANNE [FR]

Title: Transdermal Administration of Active Agents for Systemic Effect

Applicant/Assignee:

Application No.: 12/086047   Filing Date: 07/Dec/2006

Abstract:The present invention relates to compositions for transdermal administration of a therapeutic agent for providing a systemic therapeutic effect. In particular, the invention relates to spreadable compositions, or compositions which may be solid at a temperature of about 25 DEG C. or less and have a softening point of not higher than 35 DEG C., wherein transdermal administration of the therapeutic agent may be either rapid or sustained.

Priority: GB20050024961 Applic. Date: 2005-12-07; WO2006GB50437 Applic. Date: 2006-12-07

Inventor: STANIFORTH JOHN [GB]; GOGGIN PAUL [GB]

Title: Fused stem cells useful for the treatment of diabetes and methods thereof

Applicant/Assignee:

Application No.: 12/311090   Filing Date: 19/Sep/2007

Abstract:Methods disclosed include methods of treating T1DM, said method comprising delivering a therapeutic amount of beta-MSC to a subject in need thereof. Further disclosed are fusion cells comprising and MSC and a second cell wherein the nuclei of the MSC and the second cell are not fused in the fusion cell.

Priority: US20060845712P Applic. Date: 2006-09-19; WO2007US20359 Applic. Date: 2007-09-19

Inventor: WESTENFELDER CHRISTOF [US]

Title: TRANSDERMAL RICINOLEIC ACID COMPOSITIONS

Applicant/Assignee:

Application No.: 12/186825   Filing Date: 06/Aug/2008

Abstract:Transdermal compositions containing castor oil are described. The compositions comprise ricinoleic acid and a transdermal vehicle with optional additional agents. One optional additional agent is an adrenergic drug which may cause the ricinoleic acid to penetrate the skin more deeply and have a longer lasting effect. The compositions can be used for treating a variety of ailments traditionally treated with castor oil or castor oil packs, without the mess and inconvenience of using castor oil packs.

Priority:

Inventor: DELPRETE KEITH [US]

Title: EFFERVESCENT TABLETS/GRANULES

Applicant/Assignee: PHYZZ, INC

Application No.: 12/536769   Filing Date: 06/Aug/2009

Abstract:This invention provides an effervescent solid form that dissolves in cold water quickly enough to not disappoint consumers yet not so quickly that the visual interest generated during the effervescent reaction is lost. This performance is achieved by forming effervescent particles that are dense enough to retard dissolution and small enough to not take too long to dissolve. The aim of this invention is to provide a beverage in solid effervescent form that takes between about 30 and about 120 seconds to dissolve in warm water. The granules may carry functional additives such as flavors, vitamins, minerals, sweeteners, colors and drugs. The granules may also be compounded of materials intended to provide relief from skin or topical discomfort, as in the form of a wash or bath additive. The granules may also be formulated to provide cleaning agents, such as ceramic cleaners and denture cleaners.

Priority: US20080086830P Applic. Date: 2008-08-07

Inventor: RAU ALLEN [US]; QUINN NICOLE [US]; STADOLNIK DONALD [US]; STERNER ERIC [US]

Title: ASSAY AND METHOD

Applicant/Assignee:

Application No.: 12/446885   Filing Date: 26/Oct/2007

Abstract:The present invention relates to a method and assay useful for determining the sensitivity of the cells of a subject to genetic damage from electromagnetic radiation. The assay may comprise a substrate suitable for mounting a sample of lymphocytes from a subject and an electromagnetic radiation source.

Priority: GB20060021272 Applic. Date: 2006-10-26; WO2007GB04082 Applic. Date: 2007-10-26

Inventor: SHARPE DAVID THOMAS [GB]; THOMAS DENYER MORGAN CLIVE [GB]; ANDERSON DIANA [GB]; BRITLAND STEPHEN THOMAS [GB]; GOPALAN RAJENDRAN [GB]

Title: Use of rice-derived products in a universal cell culture medium

Applicant/Assignee:

Application No.: 12/228172   Filing Date: 11/Aug/2008

Abstract:The invention is used as an additive to a culture medium to maintain and grow various cells including stem cells and support their manufactured and secreted products including cytokines, chemokines and growth factors in an environment which provides: a) metabolic enabling or enhancement of measurable parameters within the cellular population b) availability and usage of nutrients to cells c) distinct and positive effect on cellular dynamics (i.e. cellular proliferation and secretion of manufactured products by the cells) d) stabilized environment for maintaining conditions for growth and other cellular and metabolic processes including secretion of manufactured products including signaling factors e) enhanced biological cellular function of inherent cellular processes f) non-interference with normal cellular metabolics (i.e. signaling) g) increased protection from toxic effects to the cell h) additional benefits to the cellular population which in absence of the additive would be lacking.

Priority:

Inventor: STEELE ANN MARIE [US]; SMITH MARK DARGAN [US]; BOONCHUEN SOMCHAI [TH]

Title: Branched Polyorganosiloxanes Modified With Aromatic Substances

Applicant/Assignee: MOMENTIVE PERFORMANCE MATERIALS GMBH

Application No.: 12/531936   Filing Date: 19/Mar/2008

Abstract:The invention relates to fragrance-modified branched polyorganosiloxanes, methods for producing them and their use.

Priority: DE200710012910 Applic. Date: 2007-03-19; WO2008EP53297 Applic. Date: 2008-03-19

Inventor: LANGE HORST [DE]; ROOS CHRISTOPHER [DE]; WAGNER ROLAND [DE]; KROPFGANS MARTIN [DE]

Title: SKIN WOUND HEALING COMPOSITIONS AND METHODS OF USE THEREOF

Applicant/Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA

Application No.: 12/522446   Filing Date: 08/Jan/2008

Abstract:A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either full-length hsp90alpha or the middle domain plus the charged sequence of hsp90alpha. The composition is topically applied to skin wounds, covering the outer surface of the wound. The heat shock protein acts by promoting migration of both human epidermal keratinocyte and dermal fibroblasts to the wound in order to close, heal, and remodel the wound.

Priority: US20070879150P Applic. Date: 2007-01-08; WO2008US50520 Applic. Date: 2008-01-08

Inventor: LI WEI [US]; CHEN MEI [US]; WOODLEY DAVID T [US]

Title: METHOD OF PROMOTING SKIN COLLAGEN PRODUCTION

Applicant/Assignee: SNOW BRAND MILK PRODUCTS CO., LTD

Application No.: 12/579100   Filing Date: 14/Oct/2009

Abstract:It is intended to provide a skin collagen production promoter, foods and drinks for promoting skin collagen production and cosmetics for promoting skin collagen production which are useful in preventing skin chapping, wrinkles, worsening in skin fitness, etc. Namely, a skin collagen production promoter, foods and drinks for promoting skin collagen production and cosmetics for promoting skin collagen production which contain as the active ingredient(s) a milk-origin basic protein fraction and/or a basic peptide fraction obtained by digesting the above-described basic protein fraction with a protein digesting enzyme such as pepsin or pancreatin. The above basic protein fraction and basic peptide fraction have an effect of increasing skin collagen level.

Priority: US2003-553830 Applic. Date: 2003-05-07; WO2003JP05707 Applic. Date: 2003-05-07

Inventor: MORITA YOSHIKAZU [JP]; TAKADA YUKIHIRO [JP]; TOBA YASUHIRO [JP]; OOI WATARU [JP]; KAWAKAMI HIROSHI [JP]

Title: ANTI-WRINKLE AGENT AND ADAM INHIBITOR

Applicant/Assignee: SHISEIDO COMPANY, LTD

Application No.: 12/524528   Filing Date: 27/Dec/2007

Abstract:Disclosed is an anti-wrinkle agent for ameliorating a wrinkle (particularly a fine wrinkle) developed when the barrier function is decreased by dryness and the like. Also disclosed is an ADAM inhibitor. The anti-wrinkle agent or the ADAM inhibitor comprises an alkyl glucoside represented by the general formula: (1) [wherein R represents a linear or branched alkyl group having 1 to 18 carbon atoms] or a salt thereof.

Priority: JP20070016535 Applic. Date: 2007-01-26; WO2007JP75120 Applic. Date: 2007-12-27

Inventor: MATSUNAGA YUKIKO [JP]; AMANO SATOSHI [JP]; HIRUMA TAKUYA [JP]; FUKUNISHI HIROTADA [JP]; SUETSUGU MASARU [JP]; SHIBATA MICHIO [JP]

Title: KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES

Applicant/Assignee:

Application No.: 12/579024   Filing Date: 14/Oct/2009

Abstract:The invention relates to a kit for the topical and/or internal application of a polymerisable adhesive composition to tissues, enabling improved control of the polymerisation speed on the surface of the tissue, in addition to the effective disinfection of the wound. The kit consists of at least one receptacle and contains a polymerisable adhesive composition based on cyanacrylate, in addition to a disinfectant composition.

Priority: DE200710019044 Applic. Date: 2007-04-20; WO2008EP54346 Applic. Date: 2008-04-10

Inventor: BROADLEY KENNETH N [IE]; GUTHRIE JOHN [IE]; SWORDS NOELEEN [IE]

Title: METHOD OF UTILISING MEASUREMENTS OF THRESHOLD OF PAIN

Applicant/Assignee: ULL METER A/S

Application No.: 12/440438   Filing Date: 10/Sep/2007

Abstract:A method of determining the sympathetic tone and/or level of stress and/or level or warning system sensitivity includes the steps of: measuring an applied stimulation at a threshold value of the stimulation in one or more sympathetic tone-neutral points and measuring an applied stimulation at the same threshold value in one or more sympathetic tone-dependent points. The invention further relates to a system for applying and measuring a stimulation, and the use of a system for applying and measuring a stimulation for determining the sympathetic tone including the steps of: measuring an applied stimulation at a threshold value of the stimulation at one or more sympathetic tone-neutral points and measuring an applied stimulation at the same threshold value of the stimulation at one or more sympathetic tone-dependent points.

Priority: DK20060001159 Applic. Date: 2006-09-08; DK20060001321 Applic. Date: 2006-10-11; DK20070000190 Applic. Date: 2007-02-02; EP20070109765 Applic. Date: 2007-06-06; US20060842984P Applic. Date: 2006-09-08; US20060829068P Applic. Date: 2006-10-11; US20070924986P Applic. Date: 2007-06-07; WO2007EP59471 Applic. Date: 2007-09-10

Inventor: BALLEGAARD SOREN [DK]; MAGNUSSON GISLI [DK]

Title: CUT RESISTANT DAMAGE TOLERANT CHEMICAL AND LIQUID PROTECTIVE GLOVE WITH ENHANCED WET AND DRY GRIP

Applicant/Assignee: ANSELL HEALTHCARE PRODUCTS LLC

Application No.: 12/542443   Filing Date: 17/Aug/2009

Abstract:A damage tolerant cut resistant chemical handling glove that is flexible and lightweight comprises a cured, liquid-impervious polymeric latex shell, a knitted cut resistant liner comprising a cotton yarn and at least one cut resistant yarn, the liner being infiltrated with a soft nitrile or polyurethane layer such that the liner bonds to the shell. The soft nitrile or polyurethane layer seals interstices of the cut resistant liner and replicates its rough texture on the external surface of the glove, providing enhanced grip properties. A thin nitrile latex layer applied to and cured together with the polyurethane layer to protect the polyurethane layer from oil or chemical degradation. The intimate seal thus created between the shell and the liner prevents accumulation of liquid there between, which prevents formation of a liquid boundary layer and interference with grip properties of the glove.

Priority: US20080089664P Applic. Date: 2008-08-18

Inventor: SAUNDERS PAUL [GB]; FLATHER MICHAEL [GB]; NARASIMHAN DAVE [US]; BENNETT WILLIAM [US]

Title: Penetrating pharmaceutical foam

Applicant/Assignee: FOAMIX LTD FOAMIX, LTD

Application No.: 10/922358   Filing Date: 20/Aug/2004

Abstract:The invention relates to an alcohol-free cosmetic or pharmaceutical foam composition comprising water, a hydrophobic solvent, a surface-active agent, a gelling agent, an active component selected from the group of urea, hydroxy acid and a therapeutic enhancer and a propellant. The foam further comprises active agents and excipients with therapeutic properties having enhanced skin penetration.

Priority: IL20020152486 Applic. Date: 2002-10-25; WO2003IB05527 Applic. Date: 2003-10-24; US2004-911367 Applic. Date: 2004-08-04; US20030497648P Applic. Date: 2003-08-25; US20020429546P Applic. Date: 2002-11-29; US20030492385P Applic. Date: 2003-08-04

Inventor: TAMARKIN DOV [IL]; FRIEDMAN DORON [IL]; EINI MEIR [IL]

Title: Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products

Applicant/Assignee:

Application No.: 12/541406   Filing Date: 14/Aug/2009

Abstract:Disclosed are methods of solubilizing various coolants, in particular cyclohexane-based carboxamide derivatives to facilitate formulating these coolants into a wide variety of consumer products, including those for oral cavity, throat, skin and hair care applications. Suitable solvents are those that provide at least 5% concentrated solutions of these coolants. Particularly preferred solvents are those used in the perfume and flavor industries and are GRAS materials that do not contribute formulation difficulties or negative aesthetics.

Priority: US20080089093P Applic. Date: 2008-08-15

Inventor: HAUGHT JOHN CHRISTIAN [US]

Title: Steroidal compounds as melanogenesis modifiers and uses thereof

Applicant/Assignee: SKINMEDICA, INC

Application No.: 12/587882   Filing Date: 13/Oct/2009

Abstract:Provided are steroidal compounds of formula I, for example, conessine, and the use of such compounds and compositions thereof to modulate (e.g., inhibit) melanogenesis and pigmentation. Also provided are plant extracts containing a compound of formula I, for example, conessine, and the use of such a plant extract to modulate (e.g., inhibit) melanogenesis and pigmentation. The compound or plant extract may be prepared as pharmaceutical and cosmetic compositions, and may be used for the prevention and treatment of conditions that are related to aberrant melanogenesis activity.

Priority: US2009-433322 Applic. Date: 2009-04-30; US20080049114P Applic. Date: 2008-04-30

Inventor: ORLOW SETH J [US]; KOMATSU LI NI [US]

Title: Use of HMGB1 antagonists for the treatment of inflammatory skin conditions

Applicant/Assignee:

Application No.: 11/988896   Filing Date: 11/Jul/2006

Abstract:Methods are disclosed for treating an inflammatory skin condition in a subject. The methods comprise administering to a subject an HMGB antagonist, such as a high mobility group box (HMGB) A box or a biologically active fragment thereof, an antibody to HMGB or an antigen-binding fragment thereof, an HMGB small molecule antagonist, an antibody to TLR2 or an antigen-binding fragment thereof, a soluble TLR2 polypeptide, an antibody to RAGE or an antigen-binding fragment thereof, a soluble RAGE polypeptide and a RAGE small molecule antagonist.

Priority: US20050700704P Applic. Date: 2005-07-18; WO2006US27053 Applic. Date: 2006-07-11

Inventor: WAHREN-HERLENIUS MARIE [SE]; NYBERG FILIPPA [SE]; MARCHINI GIOVANNA [SE]

Title: COMPOUND FOR EXFOLIATING SKIN

Applicant/Assignee:

Application No.: 12/538212   Filing Date: 10/Aug/2009

Abstract:A novel exfoliating compound and method for treating acne without an irritating cleanser. The compound includes a first subcompound formed from a clay based substance and a second subcompound formed an exfoliating substance selected from the group consisting of crystals, beads, polyethylene, nuts, natural rough products, corundum crystals, crushed almond shells and crushed apricot kernels.

Priority: US20080088147P Applic. Date: 2008-08-12

Inventor: SCHWARTZ NEAL [US]

Title: Chemical composition for skin care formulations

Applicant/Assignee:

Application No.: 12/222803   Filing Date: 15/Aug/2008

Abstract:The present invention provides preservative compositions suitable for replacing, partially or in totality, conventional preservatives in skin care and hygiene cosmetic or pharmaceutical products. The preservative formulations include an organic carboxylic acid present in a concentration from about 0.01 to about 30 wt./wt. % of the formulation, an alcohol present in a concentration from about 0.01 to about 60 wt./wt. % of the formulation. The formulations include an inorganic salt present in a concentration from about 0.01 to about 80 wt./wt. % of the formulation, and a chelating agent present in a concentration from about 0.01 to about 20 wt./wt. % of the formulation.

Priority:

Inventor: GRASCHA PIERRE BRUNO [FR]; BATTUT MYLENE [FR]

Title: Composition and method for weight reduction

Applicant/Assignee:

Application No.: 12/228845   Filing Date: 18/Aug/2008

Abstract:Disclosed is a composition and method for facilitating weight loss in individuals. The composition is a physiologically effective amount of the herbal substance Bauhinia in a suitable carrier. The carrier can be water, alcohol, mixtures thereof, capsules, powders, tinctures, liposomes, chewing gum, lozenges, candies, food, skin creams, or lotions. The method is to administer a physiologically effective amount of the herbal substance to an individual seeking to lose weight. The preferred herbal substance is obtained from the leaves of a Bauhinia forficata tree.

Priority:

Inventor: TAI PAUL LING [US]

Title: METHOD OF ANTI-AGEING COSMETIC CARE BY STIMULATION OF SURVIVIN EXPRESSION

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/477409   Filing Date: 03/Jun/2009

Abstract:The invention relates to a cosmetic care method comprising the delivery of an effective amount of at least one cosmetically acceptable agent that activates or stimulates survivin expression in the stem cells of the basal layer of the epidermis. The invention makes it possible in particular to prevent or delay the appearance of the signs of skin aging or to treat them.

Priority: FR20080053794 Applic. Date: 2008-06-06

Inventor: DUMAS MARC [FR]; BONTE FREDERIC [FR]; RENIMEL ISABELLE [FR]

Title: HERBAL COMPOSITION FOR THE PREVENTION OF WRINKLES AND SKIN DISORDERS, METHODS OF PREPARING THE SAME AND USES THEREOF

Applicant/Assignee: HIMALAYA GLOBAL HOLDINGS, LTD

Application No.: 12/440917   Filing Date: 11/Mar/2009

Abstract:Disclosed is a natural herbal composition for preventing wrinkles and other skin disorders due to aging, stress and environmental factors without any side effect. The composition comprises extracts of Rhodomyrtus tomentosa, Cipadessa baccifera, Woodfordia fruticosa and Camellia sinensis.

Priority: WO2006IN00347 Applic. Date: 2006-09-12

Inventor: MITRA SHANKAR KUMAR [IN]; SAXENA EKTA [IN]

Title: Stimulation of the synthesis and of the activity of an isoform of lysyl oxidase-like LOXL for stimulating the formation of elastic fibers.

Applicant/Assignee: BASF BEAUTY CARE SOLUTIONS FRANCE SAS

Application No.: 12/367299   Filing Date: 06/Feb/2009

Abstract:The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (lysyl oxidase-like) isoform. The Invention relates notably to a method of identifying an active principle which stimulates the formation of elastic fibers. The aim of the invention is mainly to provide such a method of identification so as to provide compositions which enable stimulating the formation of elastic fibers.

Priority: FR20030007177 Applic. Date: 2003-06-13

Inventor: PERRIER ERIC [FR]; CENIZO VALERIE [FR]; BOUEZ CHARBEL [FR]; SOMMER PASCAL [FR]; DAMOUR ODILE [FR]; GLEYZAL CLAUDINE [FR]; ANDRE VALERIE [FR]; REYMERMIER CORINNE [FR]

Title: Asthma/Allergy Therapy that Targets T-lymphoctyes and/or Eosinophils

Applicant/Assignee:

Application No.: 12/539731   Filing Date: 12/Aug/2009

Abstract:A pharmaceutical composition for the treatment and/or prophylaxis of diseases caused by type I hypersensitivity reactions consisting essentially of Glicophosphopeptical, or pure Nigella Sativa seeds, in a concentration which stimulate Th1 lymphocytes and selectively switch-off the eosinophilic airway inflammation A method of treatment of allergy using Th1 stimulating agents, to be administered to a mammal such as human in need of such treatment in a shot of 5 days only, resulted in significant decrease in symptom score started day 3, and in sputum eosinophils by day 14, followed by long-term clinical remission of a mean of 6 months. The BCG-like Th1 stimulation is also used in treating diseases in which the body defensive mechanism is a Cell Mediated Immunity, including viral infections, as but not limited to influenza and common cold, Chronic and recurrent urinary tract infection, pelvic inflammatory diseases as neuroimmune appendicitis, cancer, crohns disease and facial palsy.

Priority: GB19990004777 Applic. Date: 1999-03-02; US2001-944564 Applic. Date: 2001-09-04

Inventor: NASIF NEDAA ABDUL-GHANI [QA]

Title: Method of Promoting Wound Healing

Applicant/Assignee: CORTHERA, INC

Application No.: 12/465613   Filing Date: 13/May/2009

Abstract:The present disclosure relates to methods of administering relaxin to promote wound healing and reduce scar formation. The disclosure further contemplates the use of relaxin in reconstructive and plastic surgery.

Priority: US20080127947P Applic. Date: 2008-05-16

Inventor: STEWART DENNIS R [US]

Title: Methods for Treating or Preventing Inflammation Using a Glycerophosphate Salt

Applicant/Assignee: PRELIEF INC

Application No.: 12/526818   Filing Date: 13/Feb/2008

Abstract:Glycerophosphate salts have been found to mitigate the syndromes or conditions of discomfort associated with inflammation. Therefore, methods are provided for treating or preventing an inflammatory condition using a glycerophosphate salt. In particular, methods are provided for treating or preventing an inflammatory condition using calcium glycerophosphate (CGP).

Priority: US20070889765P Applic. Date: 2007-02-14; WO2008US53790 Applic. Date: 2008-02-13

Inventor: KLIGERMAN ALAN E [US]

Title: DERMAL COMPOSITIONS OF SUBSTITUTED AMIDES AND THE USE THEREOF AS MEDICATION FOR PAIN AND PRURITUS

Applicant/Assignee:

Application No.: 12/448760   Filing Date: 11/Jan/2008

Abstract:Dermal compositions comprising topical formulations of bupivacaine or ropivacaine, characterized by effective dermal absorption and long duration of dermal anesthetic activity, and intended for use in patients suffering from pruritus and dermal pain, including neuropathic pain, are provided. Compositions containing both bupivacaine and capsaicin are provided. Methods of alleviating pain by the topically administration of these compounds are also provided.

Priority: US20070880227P Applic. Date: 2007-01-12; WO2008US00425 Applic. Date: 2008-01-11

Inventor: ABERG A K GUNNAR [US]; JOHNSON KEITH A [US]

Title: NOVEL USE OF ORGANIC COMPOUNDS

Applicant/Assignee:

Application No.: 12/301505   Filing Date: 24/May/2007

Abstract:The present invention refers to compounds of the general formulae Ia to Ie as defined above for use as/in a composition (especially foods and dietary supplements, cosmetic, as well as pharmaceutical compositions) for the prevention and improvement of muscular disorders and for the improvement of muscle function. Other fields of use are disorders connected to impaired lipid metabolism, impaired glucose metabolism and impaired insulin action, obesity, overweight conditions, eating disorders such as bulimia and anorexia nervosa, cardiovascular diseases, atherosclerosis, vascular diseases, heart failure, inflammatory disorders such as arthritis, rheumatoid arthritis, osteoarthritis, gout, gastrointestinal disorders such as inflammatory bowel syndrome, Crohn's disease, gastritis, irritable bowel syndrome and ulcerative colitis, skin related conditions such as psoriasis, eczema, burns, dermatitis, and allergy, respiratory disorders such as asthma, chronic obstructive pulmonary disease (COPD), allergic diseases, and/or bone disorders such as osteoporosis and osteopenia. The compounds may also be used for bodyshaping, for improving the muscle:fat ratio or for accelerating skin wound healing. The present invention is also directed to dietary compositions such as (fortified) food, beverages, (fortified) feed, food additives, beverage additives, feed additives, clinical nutrition, dietary supplements, functional food, functional feed and nutraceuticals and to pharmaceutical compositions containing such compounds, to methods of treating the above mentioned disorders/diseases in mammals including humans and to the compounds of the formula I themselves. Another object of the present invention is the use of such compounds for the manufacture of a composition for the treatment of such disorders/diseases as mentioned above.

Priority: EP20060010723 Applic. Date: 2006-05-24; WO2007EP04627 Applic. Date: 2007-05-24

Inventor: D ORAZIO DANIEL [CH]; RAEDERSTORFF DANIEL [FR]; SCHUELER GOEDE [DE]; WANG-SCHMIDT YING [CH]; WERTZ KARIN [DE]; WOLFRAM SWEN [DE]

Title: Novel natural oil gels and their application

Applicant/Assignee: APPLECHEM, INC

Application No.: 12/589358   Filing Date: 21/Oct/2009

Abstract:The invention is an article of manufacture, comprising a blend of: (A) from 1 to 50 weight percent of at least one block copolymer, wherein the block copolymer has at least one polystyrene block and at least one unsaturated rubber segment

and (B) from 99 to 50 weight percent of a natural oil. The natural oil of this invention is of natural animal, plant or vegetable oils or mixtures thereof, and the block copolymers have a polystyrene block and a rubber block where the rubber blocks are unsaturated rubbers such as polyisoprene, polybutadiene, or mixtures thereof. The block copolymers useful for the present invention are triblock polymers, radial (star) polymers, multiblock polymers, diblock polymers, or mixtures thereof.

Priority: US2007-973826 Applic. Date: 2007-10-09; US20060850586P Applic. Date: 2006-10-10; US20070900512P Applic. Date: 2007-02-09; US20070900518P Applic. Date: 2007-02-09

Inventor: LIN SAMUEL [US]

Title: Chemical compositions for skin care emulsions and heavy duty hand cleansers

Applicant/Assignee:

Application No.: 12/222806   Filing Date: 15/Aug/2008

Abstract:The present invention provides preservative compositions suitable for replacing, partially or in totality, conventional preservatives in skin care emulsions and heavy duty hand cleansers comprised of alternative molecular compounds than found in conventional preservative formulations. The preservative formulation for skin care formulations includes a fatty acid and/or ester of fatty acid present in a concentration from about 0.01 wt./wt. % to about 90 wt./wt. % of the formulation, one or more alcohols in a concentration from about 0.01 to about 60 wt./wt. % of the formulation, and a chelating agent present in a concentration from about 0.01 to about 20 wt./wt. % of the blend.

Priority:

Inventor: GRASCHA PIERRE BRUNO [FR]; BATTUT MYLENE [FR]

Title: POSITIVE PRESSURE CHAMBER FOR EXTREMITIES

Applicant/Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY

Application No.: 12/444801   Filing Date: 12/Jun/2009

Abstract:The present invention provides a positive pressure chamber for treating extremities, which is used for treating extremity swelling or edema, rehabilitation, prophylaxis for deep venous thrombosis, relieving extremity pain, improvement of extremity skin, and the like.

Priority: JP20060276735 Applic. Date: 2006-10-10; WO2007JP67078 Applic. Date: 2007-08-24

Inventor: HIRATA HITOSHI [JP]; MATSUMOTO YOSHIKI [JP]; IIDA KENICHI [JP]; MIYAGAWA TAKUYA [JP]

Title: ACUPUNCTURE AND ACUPRESSURE THERAPIES

Applicant/Assignee:

Application No.: 12/389248   Filing Date: 19/Feb/2009

Abstract:Described here are devices, methods, and kits for acupuncture or acupressure therapy. The devices may include a tissue-piercing member and a reservoir containing an agent. The devices and agents may be packaged as kits useful for relieving pain and/or treating various medical conditions. The devices, methods, and kits may enable less skilled practitioners to administer acupuncture or acupressure therapy, and may extend the duration of pain relief or other symptom relief.

Priority: US20080066327P Applic. Date: 2008-02-19; US20080061532P Applic. Date: 2008-06-13

Inventor: ORONSKY BRYAN T [US]; ORONSKY NEIL C [US]; ORONSKY ARNOLD L [US]

Title: ACTVIE SUBSTANCE COMBINATION

Applicant/Assignee: ISDIN S.A

Application No.: 12/522890   Filing Date: 11/Jan/2008

Abstract:The present invention refers to a combination of at least 2 UV-absorbing active substances (A) and (B), wherein the UV-absorbing active substance (A) is at least one heptaazaphenalene compound of the general formula (I), which is defined in the description and the UV-ab-sorbing active substance (B) is at least one compound which has its ab-sorption maximum [lambda]maX(B) in the range of UV-A or UV-B radiation.

Priority: EP20070000631 Applic. Date: 2007-01-12; WO2008EP00172 Applic. Date: 2008-01-11

Inventor: GORCHS CAPA OLGA [ES]; JIMENEZ ALONSO OSCAR [ES]; TRULLAS CABANAS CARLOS RAMON [ES]; CORBERA ARJONA JORDI [ES]; PANYELLA COSTA DAVID [ES]

Title: Novel tyrosinase-specific anti-gene oligonucleotides as depigmenting agents

Applicant/Assignee: L.V.M.H. RECHERCHE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) MUSEUM NATIONAL D'HISTOIRE NATURELLE

Application No.: 11/991317   Filing Date: 01/Sep/2006

Abstract:The present invention relates to an anti-gene oligonucleotide which hybridizes specifically with the gene encoding human tyrosinase by Hoogsteen pairing between the complementary bases, said oligonucleotide forming a triple helix structure with the human tyrosinase gene. The invention also relates to the use of said oligonucleotide as a skin-depigmenting or skin-bleaching agent in a cosmetic composition or in a dermatological composition.

Priority: FR20050008981 Applic. Date: 2005-09-01; WO2006EP65902 Applic. Date: 2006-09-01

Inventor: KURFUERST ROBIN [FR]; BONNET-DUQUENNOY MATHILDE [FR]; LAZOU KRISTELL [FR]; GIOVANNANGELI CARINE [FR]

Title: MARINE EXTRACTS AND BIOFERMENTATIONS FOR USE IN COSMETICS

Applicant/Assignee: BASF BEAUTY CARE SOLUTIONS LLC

Application No.: 12/442769   Filing Date: 26/Sep/2007

Abstract:An extract of the marine algae, Sarcodiotheca, and more particularly Sarcodiotheca gaudichaudii, is described for use in cosmetic compositions. A biofermentation of Sarcodiotheca, such as for example S. gaudichaudii, is also described. This marine bioferment is useful as a skin care active ingredient for anti-aging cosmetic applications, and particularly useful when used in combination with an extracts of red algae, such as Chondrus crispus.

Priority: US20060847236P Applic. Date: 2006-09-26; WO2007US20854 Applic. Date: 2007-09-26

Inventor: CECCOLI JOSEPH D [US]; COSTELLO BRIAN [US]; PILLAI SREEKUMAR [US]

Title: COSMETIC FORMULATIONS WITH IR PROTECTION

Applicant/Assignee:

Application No.: 11/993607   Filing Date: 21/Jun/2006

Abstract:The present invention relates to cosmetic formulations with IR protection which are distinguished by the fact that they comprise functional pigments. The invention furthermore relates to cosmetic formulations which, besides the IR pigment, comprise colorants, fillers, cosmetic active compounds and cosmetic raw materials and auxiliaries, and to the use thereof in care and decorative cosmetics.

Priority: DE200510029647 Applic. Date: 2005-06-23; WO2006EP05949 Applic. Date: 2006-06-21

Inventor: HOCHSTEIN VERONIKA [DE]; SCHMIDT CHRISTOPH [DE]; SCHOEN SABINE [DE]

Title: SEMI-FINISHED PRODUCT IN THE MANUFACTURE OF A COMPOSITION FOR SKIN OR HAIR CARE

Applicant/Assignee: OY GRANULA AB LTD

Application No.: 12/377515   Filing Date: 14/Aug/2007

Abstract:A semi-finished product is manufactured from raw liquid, extract or powder obtained from wood material, an end product composition for skin or hair care being obtained from the semi-finished product by adding one or more components thereto. The semi-finished product optionally contains a UV protector, and is a liquid, emulsion, microemulsion or nanoemulsion or a dispersion, suspension, wax, lotion or gel or a solid substance. The semi-finished product further contains an active ingredient mixture which contains phenolic compounds having antioxidative and/or microbicidal properties and/or abilities to capture free radicals. The active ingredient mixture contains as phenolic compounds at least one oligolignan, and at least two lignans, tannins or flavonoids selected from a group consisting of hydroxymatairesinol, matairesinol, oxomatairesinol, lariciresinol, cyclolariciresinol, secoisolariciresinol nortrachelogenin, pinoresinol, pinosylvine, conidendrine, melacasidine, teracasidine, ellaga-tannin or a reaction product, stereoisomer or derivative of these compounds.

Priority: FI20060000729 Applic. Date: 2006-08-14; WO2007FI00201 Applic. Date: 2007-08-14

Inventor: AHLNAS THOMAS [FI]

Title: SKIN CARE COMPOSITION

Applicant/Assignee:

Application No.: 12/450596   Filing Date: 16/Apr/2008

Abstract:Skin care emulsion compositions are disclosed comprising an oil-in-water emulsion comprising phospholipid-stabilized, submicron triglyceride particles, botanical material selected from the group consisting of a vegetal material, a marine material and combinations thereof

a polycarboxylate polymer and a phosphate ester-type emulsifier. The skin care compositions can be topically applied to the skin before, and surprisingly, together with, and/or after applying a skin colorant (i.e., pigmented) cosmetic composition to moisturize the skin and achieve, augment, and/or maintain a visibly desirable cosmetic appearance.

Priority: US20070926643P Applic. Date: 2007-04-27; WO2008US04893 Applic. Date: 2008-04-16

Inventor: GIAGNORIO GERALYNN [US]

Title: Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III

Applicant/Assignee: HENKEL AG & CO. KGAA

Application No.: 12/465983   Filing Date: 14/May/2009

Abstract:Cosmetic or dermatological sticks, especially deodorant or antiperspirant sticks, based on an oil-in-water dispersion/emulsion to be applied to the skin.

Priority: DE200610053886 Applic. Date: 2006-11-14; WO2007EP62236 Applic. Date: 2007-11-13

Inventor: BANOWSKI BERNHARD [DE]; CLAAS MARCUS [DE]; BUSE NADINE [DE]

Title: NANOCRYSTALS FOR USE IN TOPICAL COSMETIC FORMULATIONS AND METHOD OF PRODUCTION THEREOF

Applicant/Assignee: ABBOTT GMBH & CO. KG

Application No.: 12/514621   Filing Date: 19/Nov/2007

Abstract:Provided are cosmetic preparations for topical application containing nanocrystals of cosmetic actives leading to an increased bioactivity of the molecules in the skin and methods of making the cosmetic preparations. The nanocrystals can be added to any cosmetic topical formulation, e. g. creams, lotions and liposomal dispersions. The drug nanocrystals are produced by a combination process of low energy pearl milling followed by a high energy high-pressure homogenization leading to nanocrystal suspensions (nanosuspensions) of improved physical stability.

Priority: US20060866233P Applic. Date: 2006-11-17; WO2007EP09943 Applic. Date: 2007-11-19

Inventor: PETERSEN ROLF [DE]

Title: PROCESS FOR TREATING THE SKIN BY APPLYING SILICONE COMPOUNDS

Applicant/Assignee: L'OREAL

Application No.: 12/519271   Filing Date: 19/Dec/2007

Abstract:The invention relates to a cosmetic treatment method for improving the superficial appearance of the skin, and especially for reducing the visible and/or tactile irregularities of the skin, such as cutaneous microrelief. According to said method, a filling product is applied to the irregularities, said product resulting from a hydrosilylation reaction, in the presence of a catalyst, between two compounds X and Y, at least one of said compounds being a silicone compound, and both compounds being brought into contact with each other in the presence of a catalyst such that the reaction occurs at least partially on the skin.

Priority: FR20060055727 Applic. Date: 2006-12-20; US20070883171P Applic. Date: 2007-01-03; WO2007FR52563 Applic. Date: 2007-12-19

Inventor: CASSIN GUILLAUME [FR]

Title: USE OF GDF-5 FOR THE IMPROVEMENT OR MAINTENANCE OF DERMAL APPEARANCE

Applicant/Assignee: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH

Application No.: 12/524229   Filing Date: 24/Jan/2008

Abstract:The present invention is directed to novel methods and compositions containing growth factor proteins. Said compositions are specifically designed to optimize the amount of crucial structural elements of mammalian tissues. The invention is especially useful for the preservation and improvement of dermal tissue appearance.

Priority: EP20070001658 Applic. Date: 2007-01-25; WO2008EP00552 Applic. Date: 2008-01-24

Inventor: POHL JENS [DE]

Title: PEARLESCENT PIGMENTS CONTAINING COSMETIC COMPOSITIONS

Applicant/Assignee:

Application No.: 12/594509   Filing Date: 04/Apr/2008

Abstract:The present invention is directed to a cosmetic composition comprising an effect pigment based on a glass flake as a substrate with a coating, said coating comprising at least one layer of at least one high refractive material, said material having a refractive index of at least 1.8, and/or a semitransparent metal coating wherein said glass flakes comprising the following composition: 65-75 wt.-% silicon oxide, preferably SiO2 2-9 wt.-% aluminium oxide, preferably Al2O3 0.0-5 wt.-% calcium oxide, preferably CaO 5-12 wt.-% sodium oxide, preferably Na2O 8-15 wt.-% boron oxide, preferably B2O3 0.1-5 wt.-% titanium oxide, preferably TiO2 0.0-5 wt.-% zirconium oxide, preferably ZrO2 based on the weight of said glass flakes. The invention is also directed to the use of the cosmetic composition.

Priority: EP20070007257 Applic. Date: 2007-04-05; WO2008EP02712 Applic. Date: 2008-04-04

Inventor: KAUPP GUENTER [DE]; SCHMIDT ULRICH [DE]; STEINBACH KATRIN [DE]; SCHUMACHER DIRK [DE]

Title: Extracellular Matrix Compositions

Applicant/Assignee:

Application No.: 12/363488   Filing Date: 30/Jan/2009

Abstract:The present invention is directed to a method of producing compositions including embryonic proteins. The method includes culturing cells under hypoxic conditions on a biocompatible three-dimensional surface in vitro. The culturing method produces both soluble and non-soluble fractions, which may be used separately or in combination to obtain physiologically acceptable compositions useful in a variety of medical and therapeutic applications.

Priority: US20080024854P Applic. Date: 2008-01-30; US20080034361P Applic. Date: 2008-03-06; US20080050940P Applic. Date: 2008-05-06

Inventor: NAUGHTON GAIL K [US]; ZIEGLER FRANK [US]; BAUMGARTNER MARK [US]; NICKEY KYLE [US]

Title: Adjuvant for Transdermal or Transmucosal Administration and Pharmaceutical Preparation Containing the Same

Applicant/Assignee:

Application No.: 12/524748   Filing Date: 31/Jan/2008

Abstract:It is intended to provide a low molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for enhancing immunogenicity of an antigen efficiently. It can be achieved by an immunostimulant adjuvant containing at least one substance selected from the group consisting of aliphatic alcohols, free fatty acids and fatty acid derivatives but does not contain a substance represented by the following formula. (In the formula, R3 and R4 may be combined to form a cyclic ring, and R1 and R2 independently represent an alkyl side chain having 1 to 16 carbon atoms.)

Priority: JP20070022061 Applic. Date: 2007-01-31; WO2008JP51499 Applic. Date: 2008-01-31

Inventor: KUWAHARA TETSUJI [JP]; TOKUMOTO SEIJI [JP]; MATSUDO TOSHIYUKI [JP]

Title: Adhesive preparation

Applicant/Assignee: HISAMITSU PHARMACEUTICAL CO., INC

Application No.: 12/588721   Filing Date: 26/Oct/2009

Abstract:An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m224 hr measured at a temperature of 40 DEG C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 nghr/mL in terms of a mean+-standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 nghr/mL in terms of a mean+-standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.

Priority: JP20060213670 Applic. Date: 2006-08-04; US2008-227066 Applic. Date: 2008-11-06; WO2007JP65067 Applic. Date: 2007-08-01

Inventor: TSURUDA KIYOMI [JP]; YAMASOTO SHINJI [JP]; SHOHO KOUKI [JP]; NAKANISHI MASARU [JP]

Title: COMPOSITIONS FOR TOPICAL APPLICATION COMPRISING A PEROXIDE AND RETINOID

Applicant/Assignee: SOL-GEL TECHNOLOGIES LTD

Application No.: 12/525329   Filing Date: 03/Feb/2008

Abstract:The invention relates to a composition for topical application comprising as an active ingredient a peroxide and a retinoid wherein one of said peroxide and retinoid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said peroxide and retinoid is present in an uncoated free form or in a coated form of the active ingredient. The invention further relates to method for treating a surface condition in a subject using said composition, a method for preparing a composition exhibiting improved stability, and a kit comprising: (a) a first composition comprising a peroxide as a first active ingredient

and (b) a second composition comprising a retinoid as a second active ingredient

at least one of said first and said second active ingredient being coated by a metal oxide layer.

Priority: US20070898701P Applic. Date: 2007-02-01; WO2008IL00140 Applic. Date: 2008-02-03

Inventor: TOLEDANO OFER [IL]; SERTCHOOK HANAN [IL]; LOBODA NATALIA [IL]; BAR-SIMANTOV HAIM [IL]; SHAPIRO LEORA [IL]; ABU-REZIQ RAED [IL]

Title: Active Principle which is capable of inducing the conversion of inactive TGFb-Latent into active TGFb

Applicant/Assignee: BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S LABORATOIRE DE DERMOCOSMETIQUE

Application No.: 12/613964   Filing Date: 06/Nov/2009

Abstract:The invention relates to active principles which are capable of inducing the conversion of inactive TGFb-Latent into active TGFb. The invention relates in particular to the use of such an extract for the manufacture of a composition for increasing the concentration of active TGFb1 in the skin, notably in the dermis. The present invention also relates to the uses which are derived from said use, as well as to cosmetic or pharmaceutical compositions which comprise said extract.

Priority: FR20040006047 Applic. Date: 2004-06-04; US2004-966168 Applic. Date: 2004-10-04

Inventor: PERRIER ERIC [FR]; ALTOBELLI CECILE [FR]; CLEMENT ANNE [FR]; REYMERMIER CORINNE [FR]; ABDUL MALAK NABIL [FR]

Title: Oxidized lipids and uses thereof in the treatment of inflammatory diseases and disorders

Applicant/Assignee: VASCULAR BIOGENICS LTD

Application No.: 12/588371   Filing Date: 14/Oct/2009

Abstract:Novel synthetic oxidized lipids and methods utilizing oxidized lipids for treating and preventing an inflammation associated with an endogenous oxidized lipid are provided.

Priority: US2006-528657 Applic. Date: 2006-09-28; US2008-567543 Applic. Date: 2008-04-25; WO2004IL00453 Applic. Date: 2004-05-27; US2003-445347 Applic. Date: 2003-05-27

Inventor: HARATS DROR [IL]; GEORGE JACOB [IL]; HALPERIN GIDEON [IL]; MENDEL ITZHAK [IL]

Title: TOPICAL COMPOSITIONS COMPRISING 5-ALPHA REDUCTASE INHIBITORS

Applicant/Assignee:

Application No.: 12/544737   Filing Date: 20/Aug/2009

Abstract:The present invention relates to topical compositions comprising 5[alpha]-reductase inhibitors. The present invention also includes processes for preparation of such topical compositions and methods of using them.

Priority: IN2008CH02033 Applic. Date: 2008-08-21; US20080106733P Applic. Date: 2008-10-20

Inventor: KANDAVILLI SATEESH [IN]; NALAMOTHU VIJENDRA [US]; PANDYA VISHVABHAVAN [IN]

Title: USE OF PIPERIDINE DERIVATIVES AS DERMO-DECONTRACTING AGENTS

Applicant/Assignee: L'OREAL

Application No.: 12/607824   Filing Date: 28/Oct/2009

Abstract:The present invention relates to a cosmetic process for treating wrinkled skin, in particular the skin of the face and/or of the forehead, through a dermo-decontracting effect, comprising the topical application to said skin of a composition comprising, in a physiologically acceptable medium, at least one piperidine derivative chosen from the compounds of formula (I): These compounds make it possible to combat expression wrinkles according to a mechanism of dermo-decontraction.

Priority: FR20040051396 Applic. Date: 2004-07-01; US2007-631391 Applic. Date: 2007-02-02; WO2005EP07975 Applic. Date: 2005-06-15; US20040589563P Applic. Date: 2004-07-21

Inventor: CAVEZZA ALEXANDRE [FR]; ROZOT ROGER [FR]

Title: Perfume Composition For Temperature Sense Control, Sense Control Article, Sense Control Method, And Perfume Map

Applicant/Assignee: SHISEIDO CO., LTD

Application No.: 12/545914   Filing Date: 24/Aug/2009

Abstract:It is an object of the present invention to discover that a perfume can change a person's temperature sense and humidity sense, to identify a perfume component that can change temperature sense, and to provide a perfume composition for controlling temperature sense that contains this perfume component, and to a sense control method or sense control article such as an aromatic or a cosmetic that is beneficial for controlling temperature sense, and to a perfume map for selecting a perfume suited to controlling temperature sense. The perfume composition is characterized in that a perfume component that changes the temperature subjectively sensed by a person (temperature sense) is contained, and that the perfume component that changes the temperature sense is a perfume component identified on the basis of a temperature image obtained from test subject assessment.

Priority: JP20030314742 Applic. Date: 2003-09-05; US2006-570634 Applic. Date: 2006-03-03; WO2004JP12659 Applic. Date: 2004-09-01

Inventor: SHOJI KEN [JP]; TAGUCHI SUMIE [JP]; TERAJIMA YUSHI [JP]

Title: Ethoxylated and/or Hydrogenated Oil Adduct

Applicant/Assignee: COLGATE-PALMOLIVE COMPANY

Application No.: 12/528889   Filing Date: 20/Nov/2008

Abstract:A composition of matter comprising an oil adduct synthesized by an oil and an addition material, wherein the oil includes at least one member chosen from an ethoxylated oil, a hydrogenated oil, and an ethoxylated and hydrogenated oil: wherein the average degree of ethoxylation in the ethoxylated (optionally hydrogenated) oil is less than about 10 based on moles of ethylene oxide per mole of oil: wherein the hydrogenated (optionally ethoxylated) oil has an iodine value of less than about 75: wherein the oil is capable of undergoing reaction with the addition material through a hydroxyl group of tile oil

and wherein the addition material includes at least one member chosen from carboxylic acid anhydrides, maleic anhydride, dicarboxylic acids, fumaric acid, maleic acid, succinic acids alpha hydroxy acids, beta hydroxy acids, lactic acid, glycolic acid, lactobionic acid, carnitine, salicylic acid, and (meth)acrylic acid.

Priority: US20070990801P Applic. Date: 2007-11-28; WO2008US84178 Applic. Date: 2008-11-20

Inventor: SUBRAMANYAM RAVI [US]; MATTAI JAIRAJH [US]; POTNIS SHASHANK [IN]; WU QIANG [US]; XU GUOFENG [US]

Title: Use of cyclopamine in the treatment of basal cell carcinoma and other tumors

Applicant/Assignee:

Application No.: 10/682584   Filing Date: 09/Oct/2003

Abstract:This invention concerns the use of cyclopamine in vivo on basal cell carcinomas (BCC's) to achieve therapeutic effect by causing differentiation of the tumor cells and, at the same time, apoptotic death and removal of these tumor cells while preserving the normal tissue cells, including the undifferentiated cells of the normal epidermal basal layer and hair follicles. Causation of apoptosis by cyclopamine is by a non-genotoxic mechanism and thus unlike the radiation therapy and most of the currently used cancer chemotherapeutics which act by causing DNA-damage. These novel effects, previously unachieved by a cancer chemotherapeutic, make the use of cyclopamine highly desirable in cancer therapy, in the treatment of BCC's and other tumors that use the hedgehog/smoothened signal transduction pathway for proliferation and prevention of apoptosis.

Priority: WO2001TR00027 Applic. Date: 2001-07-02; WO2002TR00017 Applic. Date: 2002-04-19

Inventor: TAS SINAN [TR]; AVCI OKTAY [TR]

Title: Composition based on xanthoxyline and its use in cosmetic

Applicant/Assignee: PIERRE FABRE DERMO-COSMETIQUE

Application No.: 12/310960   Filing Date: 11/Sep/2007

Abstract:The present invention relates to the use of xanthoxyline, and of plant extracts containing it, in cosmetic compositions.

Priority: FR20060008129 Applic. Date: 2006-09-15; WO2007FR01467 Applic. Date: 2007-09-11

Inventor: CHARVERON MARIE [FR]; BELAUBRE FRANCOISE [FR]; BELLE RENE [FR]; DUNOUAU CHRISTOPHE [FR]

Title: COSMETIC PREPARATIONS BASED ON MOLECULARLY IMPRINTED POLYMERS

Applicant/Assignee: BASF SE

Application No.: 12/441757   Filing Date: 14/Sep/2007

Abstract:The present invention relates to cosmetic or dermatological formulations comprising at least one active compound, at least one polymer which is molecularly imprinted in the presence of this active compound and at least one fatty phase.

Priority: EP20060120922 Applic. Date: 2006-09-19; WO2007EP59683 Applic. Date: 2007-09-14

Inventor: WENDEL VOLKER [DE]; BRUEGGEMANN OLIVER [DE]; PTOCK ARNE [DE]

Title: System and Method of Treating Skin Imperfections Including a Diagnostic Tool

Applicant/Assignee:

Application No.: 12/615797   Filing Date: 10/Nov/2009

Abstract:A system and method of treating skin imperfections including a diagnostic tool is disclosed. In a particular embodiment the system includes a diagnostic tool to scan a preselected area of skin of a client to detect at least one skin imperfection and an associative module to associate a skin value to the client. Further, the system includes that a first unadulterated ingredient of alpha lipoic acid, dimethylaminoethenol, vitamin A, vitamin C, and vitamin E, or any combination thereof, is selected based on the skin value, and a second unadulterated ingredient of retinol, alpha and beta hydroxyl acids, or any combination thereof, is selected based on the skin value. In addition, a customized product is compounded using selected first and second unadulterated ingredients and the product is compounded manually by a technician at a point of sale.

Priority: US2004-007904 Applic. Date: 2004-12-08

Inventor: HEEHLER CHARLES R [US]

Title: Expansion Units for Attachment to Custom Patterned Wound Dressings and Custom Patterned Wound Dressings Adapted to Interface With Same

Applicant/Assignee:

Application No.: 12/196908   Filing Date: 22/Aug/2008

Abstract:A custom fabricated (e.g. custom shaped and dimensioned) primary wound dressing part that matches a corresponding, pre-mapped integumentary wound is combined with dressing extension parts to form a composite wound dressing system. The primary wound dressing part may include one or more liquid flow barriers composed for example of a hydrophobic and high viscosity liquid embedded in a layer of the primary wound dressing part. The dressing extension parts may include interconnect portals for operatively interconnecting with the primary wound dressing part so that liquids may be securely moved between primary wound dressing part and the extension parts.

Priority:

Inventor: SINIAGUINE OLEG [US]

Title: SYNTHETIC WOVEN PATIENT GOWN FOR PREVENTING AND REDUCING SKIN WOUNDS

Applicant/Assignee: PRECISION FABRICS GROUP, INC

Application No.: 12/501915   Filing Date: 13/Jul/2009

Abstract:A patient gown comprised of therapeutic fabric for the prevention and treatment of skin wounds, and pressure wounds in particular, which includes a woven fabric having warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns is at least about 40% by weight of the fabric of continuous filament nylon, and the other of the warp or filling yarns is from about 0% to about 60% by weight of the fabric of continuous filament polyester or nylon having non-round filament cross sections. The fabric includes a conductive yarn at about 1% to about 2% by weight to control static dissipation, and an antimicrobial substance is topically applied or inherently available in the fabric. A method of using the patient gown to prevent and treat skin wounds, and pressure wounds in particular, is also disclosed.

Priority: US2005-152914 Applic. Date: 2005-06-13; US2004-985739 Applic. Date: 2004-11-10

Inventor: LEONARD W ALLEN [US]; BLANTON NEIL [US]; MONTGOMERY TERRY [US]; MCCALL JONES [US]

Title: FACE PLATE, VIBRATION SPEAKER HAVING FACE PLATE, AND PORTABLE TERMINAL INCLUDING THE SAME

Applicant/Assignee:

Application No.: 12/312758   Filing Date: 27/Nov/2007

Abstract:A vibration speaker with facial plate has developed for delivering sound in a form of vibrational movement to a user's skin. The vibration speaker includes a voice coil to generate a magnetic force in response to application of a sound signal from an exterior, a magnet having a predetermined magnetic force to interact with the magnetic force from the voice coil, a basket to receive the magnet, a face plate to deliver upward and downward movement of the voice coil or the magnet to the user's skin, and a rear cover coupled to the face plate to constitute an appearance of the vibration speaker. The face plate is provided with a plate-shaped tensioner providing a predetermined tension for maintaining the face plate in a horizontal state to control upward and downward vibrational movement delivered from the vibration speaker.

Priority: KR20060118312 Applic. Date: 2006-11-28; WO2007KR06018 Applic. Date: 2007-11-27

Inventor: CHOI SEONG SIK [KR]

Title: COMBINATIONS FOR ORAL COMPOSITIONS, THEIR PREPARATION AND USE

Applicant/Assignee: ORALDENT LIMITIED

Application No.: 12/374443   Filing Date: 20/Jul/2007

Abstract:A composition having a pH in the range of from 3 to 8.5, comprising: (a) in the range of from 0.1% to <10% w/w (based on the total weight of the composition) of a stock solution comprising a mixture of bioflavonoids and fruit acids or salts thereof

(b) sodium hyaluronate

and (c) water

and, optionally, (d) a pharmaceutically acceptable carrier therefor

wherein the sodium hyaluronate has an average molecular weight of between 800,000 and 4,000,000.

Priority: GB20060014353 Applic. Date: 2006-07-20; WO2007GB02756 Applic. Date: 2007-07-20

Inventor: RIPLEY IAN [GB]; THOMAS HOWARD [GB]

Title: TOPICAL FORMULATIONS OF TELLURIUM-CONTAINING COMPOUNDS

Applicant/Assignee: BIOMAS LTD

Application No.: 12/440727   Filing Date: 10/Sep/2007

Abstract:Novel formulations of tellurium-containing compounds, which are suitable for topical application, are disclosed. The formulations are characterized by high chemical and physical stability and are easy to handle and use.

Priority: US20060843402P Applic. Date: 2006-09-11; WO2007IB04220 Applic. Date: 2007-09-10

Inventor: ALBECK MICHAEL [IL]; SREDNI BENJAMIN [IL]; FIREDMAN DORON [IL]

Title: ASSOCIATION OF COMPOUNDS INHIBITING MELANOGENESIS AND USE THEREOF IN COSMETICS AND DERMATOLOGY

Applicant/Assignee: LABORATOIRES MAYOLY SPINDLER

Application No.: 12/522261   Filing Date: 15/Jan/2008

Abstract:The invention relates to an association including at least : a MC1-R receptor inhibitor

a tyrosinase inhibitor derived from vitamin C

an inhibitor of the transfer of melanosomes to the keratinocytes

the invention also relates to the use thereof in cosmetics and dermatology for preparing whitening and/or bleaching depigmentation compositions.

Priority: FR20070000279 Applic. Date: 2007-01-16; WO2008FR00040 Applic. Date: 2008-01-15

Inventor: CRITON MARC [FR]; LEMELLAY HAMON VERONIQUE [FR]; LEBLOND YVES [FR]

Title: COSMETIC COMPOSITION

Applicant/Assignee:

Application No.: 12/516347   Filing Date: 27/Nov/2007

Abstract:The problem of the present invention is to provide a cosmetic composition, which has a moisturizing effect, and whose ability to inhibit hyaluronidase activity is high. According to the present invention, by using one or more substances selected from sulfated cellulose and a salt thereof in combination with polyhydric alcohol, the moisturizing effect of sulfated cellulose and the ability to inhibit hyaluronidase activity can be further improved, and thereby the above-described problem can be solved. In addition, the present invention can provide a cosmetic composition having excellent stability through inclusion of an electrolyte having pH buffering ability.

Priority: JP20060317992 Applic. Date: 2006-11-27; WO2007JP73275 Applic. Date: 2007-11-27

Inventor: YOSHIDA NAOYUKI [JP]; YAMAMOTO YUICHI [JP]; ISHIDA KAZUSHI [JP]; YODA AKIKO [JP]; SASAKI SYUJI [JP]

Title: BLOCK COPOLYMER, COMPOSITION COMPRISING IT AND COSMETIC TREATMENT PROCESS

Applicant/Assignee: L'OREAL S.A

Application No.: 12/612554   Filing Date: 04/Nov/2009

Abstract:The present invention relates to a linear ethylenic block copolymer comprising in each block at least one ionic hydrophilic unit, which may be different from one block to another, the said ionic hydrophilic unit being present in each block in a proportion of from 2% to 100% by weight relative to the weight of the said block. The invention also relates to a cosmetic or pharmaceutical composition comprising such a copolymer, and also to a cosmetic process for making up or caring for keratin materials using the said composition.

Priority: FR20040050718 Applic. Date: 2004-04-09; US2005-101648 Applic. Date: 2005-04-08; US20040562255P Applic. Date: 2004-04-15

Inventor: BOUPAT NICOLAS PASSADE [FR]; GUERRET OLIVIER [FR]; MOUGIN NATHALIE [FR]; SCHULTZE XAVIER [FR]; HERNANDEZ FRANCK [FR]

Title: LONG-LASTING ABSORPTION OF FLAVONOIDS

Applicant/Assignee: NESTEC S.A

Application No.: 12/438501   Filing Date: 22/Aug/2007

Abstract:The present invention relates to methods for a long-term and sustained release of flavonoids, in particular rhamnose-containing flavonoids, and for prolonging the uptake of said flavonoids in the gastro-intestinal tract. It further relates to compositions comprising said flavonoid and [alpha]-rhamnosidase. It also encompasses compositions comprising hesperidin and hesperetin-7-glucoside.

Priority: EP20060017678 Applic. Date: 2006-08-24; WO2007EP07394 Applic. Date: 2007-08-22

Inventor: RICHELLE MYRIAM [CH]; WILLIAMSON GARY [GB]; JANKOVIC IVANA [CH]; REIN MAARIT [CH]

Title: CXCR4 Antagonists for Wound Healing and Re-Epithelialization

Applicant/Assignee: HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENTLTD KYOTO UNIVERSITY

Application No.: 11/915428   Filing Date: 21/May/2006

Abstract:The present invention provides novel uses for CXCR4 antagonists, including specifically peptides of the T-140 family, in the treatment of skin burns and other injuries. The invention further provides methods for increasing epithelialisation in a subject in need thereof, and for preventing or inhibiting fibrosis and excessive scar formation, using peptide inhibitors of the T-140 family as well as other CXCR4 antagonists.

Priority: US20050684160P Applic. Date: 2005-05-25; WO2006IL00596 Applic. Date: 2006-05-21

Inventor: PELED AMNON [IL]; FUJII NOBUTAKA [JP]

Title: METHODS AND TOPICAL FORMULATIONS COMPRISING COLLOIDAL METAL FOR TREATING OR PREVENTING SKIN CONDITIONS

Applicant/Assignee:

Application No.: 12/488502   Filing Date: 19/Jun/2009

Abstract:In preferred embodiments, the present invention relates to compositions comprising colloidal metals and/or metals for the treatment and prevention of skin conditions and/or diseases. More specifically, the disclosed metal containing compositions are useful as antioxidants, anti-aging agents, anti-wrinkle agents, anti-peroxidation agents, antimicrobial agents, anti-inflammatory agents, pain-relieving agents, wound recovery agents, sun-screens, sunblocks, and integument and skin-supporting agents when applied to the skin/integument, or administered generally to an animal or human body.

Priority: WO2007US88218 Applic. Date: 2007-12-19; US20060875998P Applic. Date: 2006-12-20

Inventor: MARGULIES JOEL [US]; JACOBS TERRY [US]

Title: HYDROGEL FACE MASK FOR DELIVERING SKIN CARE AGENTS

Applicant/Assignee:

Application No.: 12/199751   Filing Date: 27/Aug/2008

Abstract:Skin care can be provided by the skin care devices and compositions described herein. Such a skin care device can be configured to include a biocompatible hydrogel layer including one or more treatment agents, and an associated backing layer associated with the hydrogel layer.

Priority:

Inventor: AHN DONG JUNE [KR]

Title: COSMETIC COMPOSITION FOR PROTECTING SKIN AGAINST UV LIGHT AND WRINKLE IMPROVEMENT CONTAINING THE EXTRACT OF MAGNOLIA SIEBOLDII FLOWER EXTRACTS

Applicant/Assignee:

Application No.: 12/448751   Filing Date: 13/Dec/2007

Abstract:Disclosed herein is a cosmetic composition for preventing photoaging, containing an extract of Magnolia sieboldii as an active ingredient. Also disclosed is a cosmetic composition for reducing skin wrinkles containing an extract of Magnolia sieboldii as an active ingredient. The extract of Magnolia sieboldii can protect the skin against UV lights and skin damage by suppressing skin cell death and cell DNA damage, and can reduce skin wrinkles by promoting the biosynthesis of collagen and suppressing the synthesis of collagenases. Also, the cosmetic composition containing the extract of Magnolia sieboldii has an excellent effect of inhibiting skin damage caused by UV lights, and an excellent effect of reducing skin wrinkles.

Priority: KR20070001833 Applic. Date: 2007-01-08; WO2007KR06509 Applic. Date: 2007-12-13

Inventor: LEE GHANG TAI [KR]; LEE JUNG NOH [KR]; YOU YOUNG KYOUNG [KR]; LEE SEUNG JI [KR]; LEE KUN KOOK [KR]

Title: COSMETIC COMPOSITION COMPRISING A COMBINATION OF LIPOCHROMAN-6 AND AN EXTRACT OF LONGOZA, AND ITS USE

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/533106   Filing Date: 31/Jul/2009

Abstract:The invention relates to a cosmetic composition formulated for topical application to the skin, comprising as active agent a combination of lipochroman-6 and an extract of Longoza (Aframomum angustifolium). It also relates to the use of this combination in a cosmetic composition compatible with topical application, or for preparing such a composition, as an active agent intended for preventing or retarding the appearance of signs of skin ageing, such as the appearance of wrinkles or a decrease in the firmness and the elasticity of the skin, or for attenuating the effects thereof and/or for enhancing the radiance of the complexion of the skin, especially of the skin of the face, or for giving it back its natural radiance. It also relates to a method of cosmetic care of the skin, intended to prevent or to retard the appearance of signs of skin ageing, such as the appearance of wrinkles or a decrease in the firmness and elasticity of the skin, or to attenuate the effects thereof, comprising applying to at least one part of the skin of the body or the face a cosmetic composition comprising said combination.

Priority: FR20080055370 Applic. Date: 2008-08-01

Inventor: NIZARD CARINE [FR]; NOBLESSE EMMANUELLE [FR]; SCHAEFFER PHILIPPE [FR]

Title: NOVEL COMPOSITIONS

Applicant/Assignee:

Application No.: 12/373617   Filing Date: 12/Jul/2007

Abstract:The present invention relates to novel compositions comprising rosehip and at least one additional component e.g. selected from ligustilide, oleuropein (I), oleuropein aglycone (II), hydroxytyrosol, genistein, magnolol, honokiol, magnolia bark extract, cashew fruit extract and Glycyrrhiza foetida as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatment or prevention of inflammatory disorders.

Priority: EP20060014642 Applic. Date: 2006-07-14; WO2007EP06201 Applic. Date: 2007-07-12

Inventor: RAEDERSTORFF DANIEL [FR]; SCHWAGER JOSEPH [CH]; WERTZ KARIN [DE]

Title: POSITIVE SELECTION OF SERUM PROTEINS FOR PROTEOMIC ANALYSIS

Applicant/Assignee: CEDARS-SINAI MEDICAL CENTER APPLIED MINDS, INC

Application No.: 12/515388   Filing Date: 30/Nov/2007

Abstract:This invention relates to methods and kits for positive selection of species of interest based on peptide/protein sequence from a biological sample. The species of interest may be proteins and/or peptides of interest which may be placed through a mass spectrometer to obtain a blood peptide/protein signature. The blood peptide/protein signature may be used in proteomic analysis. The techniques include but are not limited to the use of collectors comprising nucleic acid molecules to extract a composition that has a lower concentration of a high abundance species of interest from a sample. This limits the level of influence that any collectors species may have on the results of a mass spectra.

Priority: US20060868266P Applic. Date: 2006-12-01; WO2007US86153 Applic. Date: 2007-11-30

Inventor: AGUS DAVID B [US]; HILLIS WILLIAM DANIEL [US]

Title: COSMETIC USE OF CHITINASE-TYPE PROTEINS

Applicant/Assignee: L'OREAL

Application No.: 12/515161   Filing Date: 19/Nov/2007

Abstract:The present invention relates to the use, notably cosmetic and/or therapeutic, of the YKL-40 protein belonging to the family of chitinase-type proteins, of polypeptides derived from this protein or analogs thereof of a nucleic acid sequence encoding such a polypeptide or of an agent that modulates the activity or expression of such a polypeptide notably for stimulation of terminal epithelial differentiation.

Priority: FR20060054986 Applic. Date: 2006-11-20; US20060874283P Applic. Date: 2006-12-12; WO2007FR01896 Applic. Date: 2007-11-19

Inventor: BERNARD DOMINIQUE [FR]; DONOVAN MARK [FR]

Title: Treatment and Method for Eliminating or Reducing Foot Odor

Applicant/Assignee:

Application No.: 12/199088   Filing Date: 27/Aug/2008

Abstract:A method of treating a person having a foot odor comprises administering an effective foot odor treatment amount of an antimicrobial preparation, such as Polymyxin B. Sulfate, Bacitracin Zinc, and an antimicrobial such as Miconazole Nitrate, terbinafine hydrochloride, undecylenic acid, tolnaftate, clotrimazole, or butenafine hydrochloride, to eliminate or reduce the symptoms of foot odor. The present invention is a topical skin preparation for treatment of foot odor. The preparation comprises Polymyxin B Sulfate and Bacitracin Zinc in combination with an antimicrobial agent. In a preferred form, the preparation further comprises, an antimicrobial such as Miconazole Nitrate. The concentrations of these constituents are 10,000 units of Polymyxin B Sulfate, 500 units of Bacitracin Zinc and 1.0 to 2.0% concentration of Miconazole Nitrate, in one preferred embodiment. Other compounds, such as herbal and fragrance additives may also be added to the preparation, for example Rose Water, Colors, Vitamin E, Aloe, Vitamin C, and Collagen. Further, other antimicrobial agents such as terbinafine hydrochloride, undecylenic acid, tolnaftate, clotrimazole, butenafine hydrochloride may be substituted for the antimicrobial agent Miconazole Nitrate. The topical skin preparation may further include Topical Erythromycin, Topical Aluminum Chloride Hexahydrate, or Tea Tree Oil. Topical Erythromycin may be used as a gel or solution with a 2.0% concentration. Topical Aluminum Chloride Hexahydrate may be used in a concentration of about 5.0% to 20.0%. Tea Tree Oil may be used in a concentration of about 0.10% to 10%.

Priority:

Inventor: LESTER ARNOLD [US]

Title: TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIBACTERIAL ACTIVITY

Applicant/Assignee: POLYPHOR LTD UNIVERSITAET ZUERICH

Application No.: 12/506794   Filing Date: 21/Jul/2009

Abstract:Template-fixed [beta]-hairpin peptidomimetics of the general formula (I) wherein Z is a template-fixed chain of 12 [alpha]-amino acid residues which, depend on their positions in the chain (counted starting from the N-terminal amino acid) are Gly, or Pro, or of certain types which, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to selectively inhibit the growth of or to kill microorganisms such as Pseudomonas aeruginosa and Acinetobacter. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials, or as medicaments to treat or prevent infections. In a specific embodiment, the template is based on the D-Pro-L-Pro dipeptides. These [beta]-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid-and solution phase synthetic strategy.

Priority: US2005-062021 Applic. Date: 2005-02-18; WO2002EP09278 Applic. Date: 2002-08-20

Inventor: VRIJBLOED JAN WIM [CH]; OBRECHT DANIEL [CH]; ROBINSON JOHN ANTHONY [CH]; SELLIER ODILE [FR]; KESSLER MARC [FR]

Title: NOVEL COMPOSITIONS

Applicant/Assignee:

Application No.: 12/373584   Filing Date: 12/Jul/2007

Abstract:The present invention relates to novel compositions comprising hydroxytyrosol and/or oleuropein (I) and at least one additional component e.g. selected from the group of ligustilide, oleuropein aglycone, magnolol, honokiol, genistein, resveratrol, EGCG, magnolia bark extract, cashew fruit extract and Glycyrrhiza foetida as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatment or prevention of inflammatory disorders.

Priority: EP20060014645 Applic. Date: 2006-07-14; WO2007EP06188 Applic. Date: 2007-07-12

Inventor: RAEDERSTORFF DANIEL [FR]; RICHARD NATHALIE [FR]; SCHWAGER JOSEPH [CH]; WERTZ KARIN [DE]

Title: USE OF TRICYCLIC DITERPENES AND THEIR DERIVATIVES FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS AND/OR JOINT DISORDERS

Applicant/Assignee:

Application No.: 12/515329   Filing Date: 21/Nov/2007

Abstract:The present invention refers to the use of at least one tricyclic diterpenes for the manufacture of a nutraceutical or pharmaceutical for the treatment, co-treatment or prevention of inflammatory disorders and/or joint disorders.

Priority: EP20060024382 Applic. Date: 2006-11-24; WO2007EP10071 Applic. Date: 2007-11-21

Inventor: RAEDERSTORFF DANIEL [FR]; SCHUELER GOEDE [DE]; SCHWAGER JOSEPH [CH]; WEHRLI CHRISTOF [CH]

Title: Preservative compositions

Applicant/Assignee:

Application No.: 12/589155   Filing Date: 19/Oct/2009

Abstract:Green and naturally derived biocides such as N[alpha]-(C1-C22) alkanoyl di basic amino acid alkyl (C1 to C22) ester salt cationic molecules can be combined with an anionic molecule not generally considered as having significant biocidal activity to provide antimicrobial, antibacterial, and/or antifungal properties with multifunctional benefits including preservative or self-preserving activity.

Priority: US2006-517147 Applic. Date: 2006-09-07; US2006-633231 Applic. Date: 2006-12-04; US2009-585695 Applic. Date: 2009-09-22; US2009-583919 Applic. Date: 2009-08-27; US20080196455P Applic. Date: 2008-10-17

Inventor: STOCKEL RICHARD F [US]; SAWYER ANTHONY JOSEPH [US]

Title: N-Substituted-P-Menthane-3-Carboxamide and Uses Thereof

Applicant/Assignee:

Application No.: 12/519801   Filing Date: 30/Nov/2007

Abstract:The present invention relates to substances and compositions having a physiological cooling effect on the skin and the mucosa of the body, especially of the oral cavity, throat and nose. More in particular, the present invention relates to N-substituted-p-menthane-3-carboxamides represented by the following formula (I): and esters thereof. These substances are capable of imparting and/or enhancing a physiological cooling effect in a product in which they are incorporated, much more effectively than the heretofore known N-substituted-p-menthane-3-carboxamides.

Priority: EP20060126622 Applic. Date: 2006-12-20; US20070982464P Applic. Date: 2007-10-25; WO2007NL50609 Applic. Date: 2007-11-30

Inventor: FURRER STEFAN MICHAEL [US]; TONDEUR SANDER [NL]; WINKEL CHRIS [NL]; RENES HARRY [NL]; DE KLERK ADRI [NL]

Title: HEPATITIS A VIRICIDE

Applicant/Assignee: ECOLAB INC

Application No.: 12/617468   Filing Date: 12/Nov/2009

Abstract:The invention relates to agents which combat the hepatitis A virus, containing only minimal amounts of chlorine-containing and/or chlorine cleaving active ingredients, or none of said substances. The inventions also relates to the use of these agents and to a method for their production.

Priority: DE19991062353 Applic. Date: 1999-12-23; US2002-168442 Applic. Date: 2002-09-18; WO2000EP12688 Applic. Date: 2000-12-14

Inventor: VON RHEINBABEN FRIEDRICH [DE]; BIERING HOLGER [DE]; BANSEMIR KLAUS-PETER [DE]; GLAESER SABINE [DE]

Title: Copolymers useful as rheology modifiers and home and personal care compositions comprising said copolymers

Applicant/Assignee: CIBA CORPORATION

Application No.: 12/548924   Filing Date: 27/Aug/2009

Abstract:The present invention relates to aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers. Also disclosed are methods for the rheological modification of aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers.

Priority: US20080190785P Applic. Date: 2008-09-02

Inventor: GRAHAM KEITH [GB]; NORMINGTON DAVID [GB]; DUNGWORTH HOWARD R [GB]; PLONKA JOHN M [GB]

Title: ABSORBENT ARTICLES COMPRISING A BODILY EXUDATE MODIFYING AGENT AND A SKIN CARE FORMULATION

Applicant/Assignee: KIMBERLY-CLARK WORLDWIDE, INC

Application No.: 12/537334   Filing Date: 07/Aug/2009

Abstract:Absorbent articles having enhanced absorption of bodily exudates are disclosed. The absorbent articles comprise a bodily exudate modifying agent and a skin care formulation. The bodily exudate modifying agent is capable of reducing the viscosity of bodily exudates such as feces and menses. The skin care formulation comprises a bodily exudate modifying agent neutralizer to neutralize the possible negative effects on skin barrier function caused by the bodily exudate modifying agents coming into direct contact with the wearer's skin.

Priority: US2004-915642 Applic. Date: 2004-08-10

Inventor: COHEN JASON C [US]; KOENIG DAVID W [US]; BROCK EARL DAVID [US]; BARATIAN STEPHEN A [US]; CUNNINGHAM COREY [US]; BALDWIN STEPHEN [US]

Title: DYNAMIC FITTING BODY ADHERING ABSORBENT ARTICLE

Applicant/Assignee:

Application No.: 12/507703   Filing Date: 22/Jul/2009

Abstract:A disposable personal care article comprises a shell having a unitary structure for disposition adjacent a wearer's vulva region, where the shell has a first side and a second side, the first side having a first area and a second area. The first area of the shell contacts to the wearer's skin and/or hair surrounding the vulva region. At least a portion of the first area comprises a body attachment means for adhering the shell directly to the skin and/or hair of the wearer. In addition, the shell has an anterior half and a posterior half where the posterior half exhibits a higher extension relative to the anterior half when a stretching force of 454 grams is applied. In some aspects, the article further includes an absorbent structure.

Priority: US2009-364486 Applic. Date: 2009-02-02; US2007-890093 Applic. Date: 2007-08-03; US2007-005793 Applic. Date: 2007-12-28

Inventor: DENNIS MELISSA [US]; ROSS RUSSELL FREDERICK [US]; HAGAN LUKE [US]; LUTZOW THOMAS ANDREW [US]; FOELSCHE GERHARD ANDREW [US]; PETRIE AIDAN J [US]; SCHINAZI ALAN [US]

Title: PROTEIN FORMULATIONS COMPRISING S1-5

Applicant/Assignee: LOCOMOGENE, INC

Application No.: 11/994327   Filing Date: 28/Dec/2005

Abstract:The present inventors discovered that knockout mice whose S1-5 gene function is lost develop age-related diseases or symptoms. In such knockout mice, bone mineral content, bone mineral density, and bone strength were found to be decreased, and the number of osteoclasts in bone tissues was found to be increased. Analysis of osteoclast-forming ability using bone marrow cells derived from the knockout mice revealed that osteoclast-forming ability is enhanced and osteoclasts are larger in the knockout mice than in wildtype mice. When purified S1-5 protein was added to this in vitro system, osteoclast-forming ability was inhibited. Furthermore, administration of purified S1-5 protein to osteoporotic model mice showed that this protein has the effect of improving osteoporosis. The above findings demonstrate that S1-5 protein is useful for treating and preventing age-related diseases such as osteoporosis.

Priority: WO2005JP12251 Applic. Date: 2005-07-01; WO2005JP24137 Applic. Date: 2005-12-28

Inventor: NAKAJIMA TOSHIHIRO [JP]; YAGISHITA NAOKO [JP]; AMANO TETSUYA [JP]

Title: ITEM OF CLOTHING

Applicant/Assignee:

Application No.: 12/450535   Filing Date: 06/Sep/2007

Abstract:The invention relates to an item of clothing, in particular to be worn during sports such as jogging, skating, cycling or similar. Said item of clothing is made of at least one yarn (3) that comprises a heat-reflecting covering (5).

Priority: DE200720005259U Applic. Date: 2007-04-10; WO2007DE01613 Applic. Date: 2007-09-06

Inventor: LAMBERTZ BODO W [CH]

Title: Personal hygiene devices to aid physically impaired users to clean their recto-genital area

Applicant/Assignee:

Application No.: 11/015768   Filing Date: 20/Dec/2004

Abstract:Personal hygiene devices designed to aid physically impaired persons to clean their own recto-genital area following urination, defecation, menstruation, or sweating. The devices include an elongated flexible strip made from one or two elongated individual sheets affixed together and of a length sufficient to extend between the user's legs and of a width sufficient to generally cover the recto-genital area. The strip has an absorbent middle portion for engaging the user's recto-genital area and respective dependent end portions having respective thumb holes therethrough for easy gripping in-hand. An absorbent pad is positioned at the middle portion retained by the individual sheets to increase the absorbency thereof. The device is used by gripping the end portions in-hand optionally using the thumb holes with the middle portion extending between the user's legs. The middle portion is moved into engagement with the user's recto-genital area and the end portions moved longitudinally while maintaining tension thereon to wipe the middle portion along the recto-genital area to remove excrement therefrom. The device is made of flushable materials for disposal down toilets following use. The devices are preferably manufactured in device sheets from rolls of raw materials using automated manufacturing equipment in which the devices are initially interconnected at perforated tear lines and subsequently separated, folded or wrapped, and individually wrapped or otherwise packaged for individual use thereof.

Priority:

Inventor: MCDOWELL KAREN S [US]

Title: SHEATHLIKE APPLICATOR AND PROCESS FOR PRODUCING THE SAME

Applicant/Assignee:

Application No.: 12/303644   Filing Date: 28/May/2007

Abstract:A sheath-shaped application implement, as well as a manufacturing method thereof, where said sheath-shaped application implement comprises a base sheet(s) and a protective film(s) that are sealed together in a manner providing an empty area in which to insert the palm or fingers, and at least one base sheet mentioned above is constituted by a retention layer having at least one type of application composition on it, and by a barrier layer, where the barrier layer prevents permeation or leakage of the application composition, while the protective film is structured in such a way as to protect the application composition from exposure to the outside. This application implement can be stored in a manner retaining the quality of the application composition, is not bulky, can be carried with ease, and when used the application implement allows the protective film to be removed with ease and the application composition to be applied to desired locations at various parts of the body.

Priority: JP20060157012 Applic. Date: 2006-06-06; WO2007JP60775 Applic. Date: 2007-05-28

Inventor: NAKAMURA KOJI [JP]; PAUCHET BERNARD [FR]; GUIMARD MICHEL [FR]

Title: PEPTIDE-BASED COMPOUNDS AS NEW INHIBITORS OF METALLOECTOPEPTIDASES, COMPOSITIONS COMPRISING SAID COMPOUNDS AND THEIR PHARMACEUTICAL AND COSMETIC USES

Applicant/Assignee: GREENPHARMA

Application No.: 12/524955   Filing Date: 04/Feb/2008

Abstract:The invention relates to a compound that inhibits a metallo-ectopeptidase, selected in the group consisting of x-aa2-aa1-z, x-aa3-aa2-aa1-z, x-aa4-aa3-aa2-aa1-z and x-aa5-aa4-aa3-aa2-aa1-z, wherein: aa1 and aa4, independently from each other, represent an arginine amino acid, an histidine amino acid, an asparagine amino acid or a lysine amino acid, aa2 represents a serine amino acid, a glycine amino acid, a threonine amino acid or an alanine amino acid, aa3 represents a phenylalanine amino acid, a leucine amino acid, an isoleucine amino acid, a tyrosine amino acid or a tryptophan amino acid, aa5 represents a glutamine amino acid, a glutamic acid amino acid, an asparagines amino-acid or a lysine amino acid, x and z, independently from each other, represent: -H

-OH1 SH

-a halogen atom, -an amino group, -an alkyl, haloalkyl or heteroalkyl group containing from 1 to 30 carbon atoms, linear or branched, -an alkenyl or alkynyl group containing from 2 to 30 carbon atoms, linear or branched, -a cycloalkyl, cycloakenyl, cycloalkynyl or an heterocyclic group containing from 3 to 30 carbon atoms, linear or branched, -one or more aryl or heteroaryl groups containing from 3 to 10 carbon atoms per cycle, -a alkoxy, thioalkyl, sulfonylalkyl, aminoalkyl containing from 1 to 30 carbon atoms, linear or branched, -one or more heterocyclic group, containing from 5 to 10 carbon atoms per cycle, said groups being optionally substituted by one or more halogen atoms, alkyl groups, hydroxy groups, alkoxy groups, aryloxy groups, acyloxy groups, carbamoyloxy groups, carboxy groups, mercapto groups, alkylthio groups, acylthio groups, arylthio groups, aryl groups, heterocyclic groups, heteroaryl groups or amino groups.

Priority: US20070899033P Applic. Date: 2007-02-02; WO2008IB01328 Applic. Date: 2008-02-04

Inventor: BERNARD PHILIPPE [FR]

Title: TREATMENT OF DAMAGED SKIN

Applicant/Assignee:

Application No.: 12/554364   Filing Date: 04/Sep/2009

Abstract:A medicament for treating skin is described. It comprises essentially of bulbine frutescens, centella asiatica and a phenol derived from olive oil preferably oleuropein. The medicament may be used in the treatment of scars formed during surgery. It may also be used cosmeceutically in the treatment of aged skin where it may be used with phosphatidylserine. The medicament can also act in conjunction with anti-acne treatment to diminish scarring from the acne condition.

Priority: ZA20080008004 Applic. Date: 2008-09-18; ZA20090004000 Applic. Date: 2009-06-08; US20080094170P Applic. Date: 2008-09-04

Inventor: WIDGEROW ALAN DAVID [ZA]

Title: Compositions and Methods of Their Use for Improving the Condition and Appearance of Skin

Applicant/Assignee: AVON PRODUCTS, INC

Application No.: 12/621027   Filing Date: 18/Nov/2009

Abstract:The present invention relates to compositions and methods for treating, preventing and improving the condition and aesthetic appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, where the compositions include natural plant constituents, or synthetic equivalents thereof, which inhibit or decrease expression of C-reactive protein expression, production or secretion, thereby reducing, inhibiting, or ameliorating dermatological signs of aging. The compositions of the invention may be topically applied to the skin, or are delivered by directed means to a site in need thereof, in an amount effective in improving the condition and aesthetic appearance of skin.

Priority: US2006-647648 Applic. Date: 2006-12-29

Inventor: DRYER LAURENCE [US]; TAFURI SHERRIE R [US]; PTCHELINTSEV DMITRI S [US]

Title: COMPOSITIONS COMPRISING KAKADU PLUM EXTRACT OR ACAI BERRY EXTRACT

Applicant/Assignee: MARY KAY INC

Application No.: 12/620410   Filing Date: 17/Nov/2009

Abstract:A topical skin care composition comprising kakadu plum extract or acai berry extract, or a combination of both, is disclosed. The composition can include a high oxygen radical absorbance capacity (ORAC) value. The composition can improve the skin's visual appearance, physiological functions, clinical properties, and/or biophysical properties.

Priority: US2007-624985 Applic. Date: 2007-01-19; US20060760103P Applic. Date: 2006-01-19; US20060760977P Applic. Date: 2006-01-20; US20060760979P Applic. Date: 2006-01-20

Inventor: GAN DAVID [US]; HINES MICHELLE [US]; ARAVENA JAVIER [US]; JONES BRIAN [US]

Title: Organic compounds

Applicant/Assignee: GIVAUDAN SA

Application No.: 12/066518   Filing Date: 08/Sep/2006

Abstract:The invention relates to organic compounds having the ability to reduce or suppress the onset of skin irritation induced by extraneous cause selected from the group of 2-heptylcyclopentanone, 2-ethoxynaphthalene

2-methoxynaphthalene

1-methoxy-4-(prop-1-enyl)benzene

1-(cyclopropylmethyl)-4-methoxybenzene

wherein X, Y, and R1 to R11 have the same meaning as given in the description. Furthermore the invention refers to compositions for topical application to the skin comprising them. It further relates to a method of reducing or suppressing the formation of skin irritation.

Priority: GB20050018558 Applic. Date: 2005-09-12; WO2006CH00481 Applic. Date: 2006-09-08

Inventor: NATSCH ANDREAS [CH]; WASESCHA MICHAEL [CH]

Title: SKIN-CARE PREPARATIONS CONTAINING MUPIROCIN AND BETAMETHASONE DIPROPIONATE

Applicant/Assignee:

Application No.: 12/065352   Filing Date: 18/Mar/2009

Abstract:The present invention relates to a topical skin-care preparation in the form of an ointment containing mupirocin and betamethasone dipropionate as active principles and a carrier formulated with all or some of the following components: hydrogenated castor oil, polyethylene glycols and preservatives. The inventive preparation is advantageous over prior art compositions in that it has a specific therapeutic effect on primary and secondary skin infections, such as relief of pruritic inflammatory manifestations of dermatosis, a wide range of activity against the majority of bacterial species involved in skin infections, and a high level of activity against Staphylococcus and Streptococcus, including multi-resistant strains. In addition, the therapeutic effect of the preparation is not affected by the size of the inoculum and the preparation has no sensitization potential, thereby providing the product with an excellent safety profile for use by the patient. Moreover, the preparation can counteract the possible secondary effects of one of the components with the effect of another.

Priority: MX2005PA09381 Applic. Date: 2005-09-02; WO2005MX00084 Applic. Date: 2005-09-28

Inventor: AHUMADA AYALA FERNANDO [MX]

Title: DEVICE AND METHOD FOR THE TREATMENT OF SKIN, AND USE OF THE DEVICE

Applicant/Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V

Application No.: 12/305438   Filing Date: 21/Jun/2007

Abstract:The invention provides a skin treatment device comprising a laser source (40) and focusing optics (50), such that a focal spot (18) is positioned in a dermis layer (24) of the skin to be treated. The laser beam (42) is powered and focused (16) such that a LIOB (laser induced optical breakdown) phenomenon is obtained, which affects the skin in order to stimulate re-growth of tissue. This in turn reduces wrinkles (30). The device may comprise wrinkle-determining means (52, 54, 56, 58). The focusing optics (50) may have a numerical aperture of at least 0.4. The invention also provides a corresponding method to treat skin, in particular to reduce wrinkles (30), by providing a focused laser beam (16) that causes LIOB in the dermis layer (24) of the skin. The advantage is that damage to overlaying epidermis layers may be avoided by the use of the very local LIOB phenomenon.

Priority: EP20060116057 Applic. Date: 2006-06-26; WO2007IB52399 Applic. Date: 2007-06-21

Inventor: VERHAGEN RIEKO [NL]; VAN HAL ROBBERT A M [NL]; GOTTENBOS BART [NL]; JANSSEN JOZEF J M [NL]; ACKERMANS PAUL A J [NL]; MORALES SERRANO FRANCISCO [NL]; NERKEN SIEGLINDE [NL]; BROKKEN DIRK [NL]; ROOSEN GUIDO [NL]

Title: Pre-Packaged, Customized, Woven, Wet Towel

Applicant/Assignee: HUCKLEBERRY TOYS

Application No.: 12/233242   Filing Date: 18/Sep/2008

Abstract:The invention relates to a pre-packaged, pre-moistened towel, which is customized. The towel is made from a woven cloth material, which can be customized by printing logos, designs or words on the towel. The towel can be either disposable or reusable.

Priority:

Inventor: STEVENSON HUGO [US]

Title: Lotion Application Compartment

Applicant/Assignee:

Application No.: 12/086098   Filing Date: 04/Dec/2006

Abstract:A lotion application compartment (10) consisting of apparatus for topical application of a fluid to a human or animal body, the apparatus comprising a spray nozzle (20) and a support (80) for the body. The apparatus further comprises of one or more of the following: means for moving the support, so as to change the distance between the body and the spray nozzle (20)

means for varying the spray pattern, spray pressure, spray frequency and/or spray duty cycle of the nozzle (20)

means for varying the rotational speed of the support (80)

and means for raising the body's skin temperature directly by radiation.

Priority: GB20050024800 Applic. Date: 2005-12-05; WO2006GB04524 Applic. Date: 2006-12-04

Inventor: HIPPERSON GERALD [RU]

Title: MAIN SEAL SYSTEM AND METHOD FOR USE IN AN ELECTRONIC DEVICE

Applicant/Assignee: MOTOROLA, INC

Application No.: 12/210638   Filing Date: 15/Sep/2008

Abstract:A main sealing system (500) for use in an electronic device comprises a first half housing (501) and a second half housing (516) such that a sympathetic seal (525) is attached integrally with the first half housing (501). The second half housing (516) comprises an integrally formed compression surface (511) for biasing the sympathetic seal (525) in an outwardly manner to prevent fluid from entering a cavity (618) formed when the first half housing (501) and second half housing (516) are joined to form an enclosure for the electronic device.

Priority:

Inventor: GARCIA JORGE L [US]; MAGANA SALVADOR P [US]

Title: AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS

Applicant/Assignee: BASF SE

Application No.: 12/441288   Filing Date: 14/Sep/2007

Abstract:The present invention relates to an ampholytic copolymer based on quaternized nitrogen-containing monomers which has a molar excess of cationogenic/cationic groups compared to anionogenic/anionic groups, to cosmetic or pharmaceutical compositions which comprise at least one such ampholytic copolymer, and to further uses of these copolymers.

Priority: EP20070111467 Applic. Date: 2007-06-29; EP20060120778 Applic. Date: 2006-09-15; WO2007EP59725 Applic. Date: 2007-09-14

Inventor: KIM SON NGUYEN [DE]

Title: TOPICAL COMPOSITION FOR THE PROTECTION AND/OR TREATMENT OF RADIATION RELATED SKIN DAMAGES

Applicant/Assignee:

Application No.: 12/559954   Filing Date: 15/Sep/2009

Abstract:There is provided a topical composition for the protection and/or treatment of radiation related skin damages comprising from 18.4% to 68% by volume of active principles comprising anti-oxidants, moisturizers, humectants, emollients, anti-inflammatory agents, healing promoting agents and dermal circulation enhancers in from 81.6% to 32% by volume of a pharmaceutically acceptable carrier.

Priority: CA20082639525 Applic. Date: 2008-09-16

Inventor: TODARY MICHAEL FAYEK [CA]

Title: Compositions Having Silicone Properties

Applicant/Assignee: LIPO CHEMICALS INC

Application No.: 12/561465   Filing Date: 17/Sep/2009

Abstract:Silicone-free, carbon-based replacements for volatile silicones, such as cyclomethicones, are disclosed. The compositions can be used as is or in dermatological products.

Priority: US20080098077P Applic. Date: 2008-09-18

Inventor: GREENBERG STEPHEN [US]; RIEMER JED A [US]

Title: Methods for treating skin lines and wrinkles and improving skin quality

Applicant/Assignee:

Application No.: 12/583944   Filing Date: 27/Aug/2009

Abstract:Methods and compositions for improving skin quality are disclosed. The methods include applying a solution of about 20-30% pre-wetting agent, such as hyaluronic acid, and/or Botulinum toxin to a skin surface with concurrent particle-free dermabrasion treatment, such as particle-free microdermabrasion treatment. These methods lead to significant improvement in the treatment of skin aging. Compositions for improving skin quality are also disclosed. These compositions comprise a pre-wetting agent and a Botulinum toxin agent.

Priority: US20080190562P Applic. Date: 2008-08-28

Inventor: KEY DOUGLAS J [US]

Title: Method And System For Providing Targeted And Individualized Delivery Of Cosmetic Actives

Applicant/Assignee:

Application No.: 12/533107   Filing Date: 31/Jul/2009

Abstract:A system and method are provided for targeted and individualized delivery of multiple skin benefit agents to the skin of a user. The image of a predetermined treatment area of the user's skin is first captured by an imaging device. The captured image data is then analyzed by a computing device to generate a unique skin profile for the user, which is indicative of the skin conditions at the predetermined treatment area. Based on such skin profile, a printing device prints out one or more cosmetic delivery sheets that can be applied to the predetermined treatment area. Each of the cosmetic delivery sheets contains a substrate with multiple isolate, discrete regions, while at least two of the regions are imprinted with different skin benefit agents for treating different skin conditions of the predetermined treatment area according to the unique skin profile of the user.

Priority: US20080097273P Applic. Date: 2008-09-16

Inventor: MOU TSUNG-WEI ROBERT [US]; MOHAMMADI FATEMEH [US]; QU LISA [US]; CZARNOTA ANNA [US]; KAMEN TAMAR LARA [US]

Title: BLEOMYCIN PREPARATION FOR USE AGAINST SKIN TUMOURS

Applicant/Assignee:

Application No.: 12/312526   Filing Date: 26/Nov/2007

Abstract:A preparation for use against skin tumours, which preparation has a semi-solid consistency for enabling the preparation to be applied to and remain on a patient's skin during treatment of a tumour on the patient's skin

which preparation comprises bleomycin which acts against the tumour, an elastic liposome which entraps the bleomycin

and a bleomycin containing carrier which contains the bleomycin in the elastic liposome

and which preparation is such that: (i) the concentration of the bleomycin in the bleomycin containing carrier is not less than the concentration of the bleomycin in the elastic liposome

(ii) the concentration of the bleomycin in the bleomycin containing carrier is not so great as to cause the bleomycin in the bleomycin containing carrier to leak into the elastic liposome and cause the elastic liposome to burst

and (iii) the external concentration of the bleomycin in the bleomycin containing carrier is such that it maintains an osmotic balance between internal and external environments of the elastic liposome whereby the internal concentration of the bleomycin in the elastic liposome is kept constant.

Priority: GB20060023768 Applic. Date: 2006-11-28; WO2007GB04517 Applic. Date: 2007-11-26

Inventor: CHOPRA SUNIL [GB]

Title: NATURAL PRODUCT INHIBITORS OF 3DG

Applicant/Assignee:

Application No.: 12/474904   Filing Date: 29/May/2009

Abstract:Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.

Priority: US20080057398P Applic. Date: 2008-05-30

Inventor: TOBIA ANNETTE [US]; ALICE MARCY [US]; SU BANGYING [US]; NIWA TAKESHI [JP]

Title: LOW FOAMING ENHANCED BIOCIDAL HYDROGEN PEROXIDE COMPOSITION

Applicant/Assignee: CENTENNIAL VENTURES B.V

Application No.: 12/226657   Filing Date: 27/Apr/2007

Abstract:The present invention discloses a biocidal composition comprising hydrogen peroxide in a concentration of 0.05-50% (w/w) and a compound with a structure according to Formula 1: R-O-(CH(Y)-CH2-O)n-CH2-COOH, wherein R is an alkyl or alkenylene radical containing 6-12 carbon atoms, Y is H or CH3, and n is 3-10, in a concentration of 0.01-60% (w/w). An especially preferred compound according to Formula 1 is R is 6 or 8 and n is 3-8.

Priority: EP20060113228 Applic. Date: 2006-04-27; WO2007EP54164 Applic. Date: 2007-04-27

Inventor: BOBBERT ILJA [NL]

Title: Coffee Cherry Cosmetic Composition and Methods

Applicant/Assignee: VDF FUTURECEUTICALS, INC

Application No.: 12/631119   Filing Date: 04/Dec/2009

Abstract:A cosmetic composition comprises a coffee cherry preparation, and most preferably an extract from a sub-ripe quick-dried coffee cherry. Particularly contemplated cosmetic compositions are formulated as a shampoo, lotion, cream, balm, or ointment, and will have at least one of an antioxidant effect, an anti-inflammatory effect, a UV-protective effect, an antimutagenic effect, a chemoprotective effect, a scar reducing effect, a skin-lightening effect, a moisturizing effect, a wrinkle reduction effect, and an antibacterial effect.

Priority: WO2003US11950 Applic. Date: 2003-04-16; WO2003US11951 Applic. Date: 2003-04-16; US2007-599663 Applic. Date: 2007-07-20; WO2004US36630 Applic. Date: 2004-11-03; US20040560865P Applic. Date: 2004-04-08; US20040618900P Applic. Date: 2004-10-12

Inventor: MILJKOVIC DUSAN [US]

Title: MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS

Applicant/Assignee:

Application No.: 12/559107   Filing Date: 14/Sep/2009

Abstract:The invention relates to a medicament comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40, said medicament being preferably intended to regulate inflammatory mechanisms. The reducing sugar is preferably selected from the group containing rhamnose, fucose and glucose. The invention also relates to a cosmetic treatment method involving the topical application of a composition comprising at lest one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40.

Priority: FR20030012798 Applic. Date: 2003-10-31; US2006-577444 Applic. Date: 2006-04-27; WO2004FR02794 Applic. Date: 2004-10-29

Inventor: HOULMONT JEAN-PHILIPPE [FR]; RICO-LATTES ISABELLE [FR]; PEREZ EMILE [FR]; BORDAT PASCAL [FR]

Title: PHARMACEUTICAL COMPOSITIONS

Applicant/Assignee: YORK PHARMA PLC

Application No.: 12/439023   Filing Date: 31/Aug/2007

Abstract:The present invention provides a composition for topical administration to the skin for treating and/or preventing a dermatological condition involving an abnormal decrease in the cell-to-cell adhesion between epithelial cells comprising a zinc salt which is at least partially soluble in water and an acid, wherein the composition has a pH less than or equal to 6. The dermatological condition is generally selected from eczema, dermatitis, atopic eczema, atopic dermatitis, non-atopic eczema, non-atopic dermatitis, seborrheic eczema, irritant contact dermatitis, allergic contact dermatitis, pruritus and sensitive skin. A preferred composition comprises zinc lactate, lactic acid and has a pH of about 4.0 to 5.0.

Priority: GB20060017191 Applic. Date: 2006-08-31; WO2007EP59102 Applic. Date: 2007-08-31

Inventor: WARD SIMON J [GB]; MACGOWAN ALICE [GB]; CORK MICHAEL J [GB]; DAVIS ADRIAN [GB]

Title: METHODS FOR TREATING INFLAMMATION AND RELATED CONDITIONS

Applicant/Assignee: ORE PHARMACEUTICALS INC

Application No.: 12/500761   Filing Date: 10/Jul/2009

Abstract:A method for treating an inflammatory condition or immune disorder comprises administering to a subject having such a condition or disorder a therapeutically effective amount of at least one compound selected from irindalone, physiologically active enantiomers thereof, and pharmaceutically acceptable salts thereof. The invention further provides a method for elevating levels of anti-inflammatory cytokines such as IL-10 and IL-13 while inhibiting expression of pro-inflammatory cytokines. A pharmaceutical composition, useful for example in topical treatment of psoriasis, comprises a therapeutically effective amount of at least one compound selected from irindalone, physiologically active enantiomers thereof, and pharmaceutically acceptable salts thereof, in a vehicle comprising at least one pharmaceutically acceptable excipient, the vehicle being adapted for topical administration to skin of a subject.

Priority: US20080079808P Applic. Date: 2008-07-10

Inventor: MALSTROM SCOTT [US]; AMUGUNI HELLEN MULOMI [US]; CLISH CLARY [US]; DEIK AMY ANDERSON [US]; WHITE DAVID [US]

Title: STABLE MIXED EMULSIONS

Applicant/Assignee: COMBE

Application No.: 12/608391   Filing Date: 29/Oct/2009

Abstract:Stable mixed emulsion systems containing at least two discrete and distinctly different dispersed particle size ranges, i.e., both nanoemulsion and macroemulsion semisolid dispersions, as well as a method of making the same, are disclosed. The stable mixed emulsions may be used for cosmetic and dermatological applications and provide unique benefits.

Priority: US2006-369831 Applic. Date: 2006-03-08; US20050659410P Applic. Date: 2005-03-09

Inventor: SPENGLER ERIC [US]; PETRAIA TERESA [US]

Title: AGENT

Applicant/Assignee: SCA HYGIENE PRODUCTS AB

Application No.: 12/515252   Filing Date: 15/May/2009

Abstract:A novel strain of Lactobacillus fermentum, denoted strain Ess-1, which has been deposited at Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH and has been assigned accession number DSM17851. Lactobacillus fermentum, strain Ess-1, has shown valuable properties in the inhibition of Candida, and has medical uses, in particular for the treatment and/or prevention of candidasis and urinary tract infections. In addition, pharmaceutical products and articles include the novel bacterial strain.

Priority: WO2006SE01311 Applic. Date: 2006-11-17

Inventor: FORSGREN BRUSK ULLA [SE]; HUSMARK ULRIKA [SE]; GRAHN HAAKANSSON EVA [SE]; ROENNQVIST DANIEL [SE]

Title: SPECTRALLY SENSING CHEMICAL AND BIOLOGICAL SUBSTANCES

Applicant/Assignee:

Application No.: 12/625970   Filing Date: 25/Nov/2009

Abstract:A sensor-network system for spectrally sensing a chemical or biological substance includes a plurality of probe assemblies that each includes a sensor comprising a nano structured surface, wherein the nano structured surface can adsorb molecules of a sample material captured adjacent to the sensor

a laser configured to emit a laser beam to illuminate the molecules adsorbed to the nano structured surface, and a spectrometer that can obtain spectral data from light scattered by the molecules adsorbed to the nano structured surface. A control center includes a computer storage configured to store spectral signatures each associated with a chemical or biological substance and a spectral analyzer that can determine a spectral signature matching at least one of the spectral signatures stored in the computer storage thereby to identify, in the sample material, the chemical or biological substance associated with the one of the spectral signatures.

Priority: US2009-403522 Applic. Date: 2009-03-13; US2008-246616 Applic. Date: 2008-10-07; US2008-176383 Applic. Date: 2008-07-20; US2007-681157 Applic. Date: 2007-03-01; US2004-987842 Applic. Date: 2004-11-12; US2004-852787 Applic. Date: 2004-05-24; US20030473283P Applic. Date: 2003-05-27; US20030473287P Applic. Date: 2003-05-27; US20030520222P Applic. Date: 2003-11-17

Inventor: WANG HONG [US]; GUO XUN [US]; LIU CHUNWEI [CN]

Title: Business_on_a_page

Applicant/Assignee:

Application No.: 12/584558   Filing Date: 08/Sep/2009

Abstract:Enterprise architecture is an emerging discipline that cuts across arts, science and religion. Enterprise architecture is increasingly seen as the best way to optimize existing IT investment while planning for future growth in areas like green IT, healthcare IT and medical tourism. Only by establishing a blueprint with which to operate can companies comply with corporate and government mandates requiring closer alignment of business processes with IT investment. Further, since change is a constant in IT, the blueprint must be dynamic enough to anticipate and adapt to evolving business models and economic trends. The blueprints are built on the Beijing Olympics with the One World theme. They cover people, plants and animals, can be applied to person and product complaints and provides the foundation for globalization, mass customization and personalized medicine.

Priority: US20080095693P Applic. Date: 2008-09-10

Inventor: HANDY ASLAM TAHER [US]

Title: Methods and Systems for Incorporating Multiple Environmental and Genetic Risk Factors

Applicant/Assignee: NAVIGENICS, INC

Application No.: 12/558345   Filing Date: 11/Sep/2009

Abstract:The present disclosure provides methods and systems for incorporating multiple environmental and genetic risk factors into an individual's genomic profile. Methods include assessing the association between an individual's genotype and at least one disease or condition by incorporating multiple genetic risk factors, environmental risk factors, or a combination of both.

Priority: US20080096758P Applic. Date: 2008-09-12

Inventor: HALPERIN ERAN [US]; WESSEL JENNIFER [US]; CARGILL MICHELE [US]; STEPHAN DIETRICH A [US]

Title: WATERPROOF MOISTURE-PERMEABLE FABRIC FOR CLOTHING AND CLOTHING

Applicant/Assignee: TEIJIN FIBERS LIMITED

Application No.: 12/527321   Filing Date: 24/Oct/2007

Abstract:The invention provides a waterproof moisture-permeable fabric for clothing which includes, on one side of a polyester fabric A, a waterproof moisture-permeable layer B including a colorless transparent polyester film stacked, and a white or gray resin C partially stacked, and clothing including the waterproof moisture-permeable fabric. Preferably, a moisture-permeable polymer resin D containing inorganic fine particles is stacked on the waterproof moisture-permeable layer B, and the white or gray resin C is partially stacked thereon.

Priority: JP20070040334 Applic. Date: 2007-02-21; WO2007JP71162 Applic. Date: 2007-10-24

Inventor: IWASHITA KENJI [JP]; ITAI HITOSHI [JP]; YAMAZAWA MOTOKI [JP]

Title: COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING HYALURONIC ACID

Applicant/Assignee: AURIGA INTERNATIONAL S.A

Application No.: 12/375857   Filing Date: 01/Aug/2007

Abstract:A cosmetic or pharmaceutical composition includes particles of hyaluronic acid having a molecular weight between 20000 Da and 3000000 Da, combined with a polyamine.

Priority: EP20060118270 Applic. Date: 2006-08-01; US20060841656P Applic. Date: 2006-08-30; WO2007EP57987 Applic. Date: 2007-08-01

Inventor: DUBOIS JACQUES [BE]; MARCHAL ALFRED [BE]

Title: Compositions Comprising Kakadu Plum Extract Or Acai Berry Extract

Applicant/Assignee: MARY KAY INC

Application No.: 12/624980   Filing Date: 24/Nov/2009

Abstract:A topical skin care composition comprising kakadu plum extract or acai berry extract, or a combination of both, is disclosed. The composition can include a high oxygen radical absorbance capacity (ORAC) value. The composition can improve the skin's visual appearance, physiological functions, clinical properties, and/or biophysical properties.

Priority: US2007-624985 Applic. Date: 2007-01-19; US20060760103P Applic. Date: 2006-01-19; US20060760977P Applic. Date: 2006-01-20; US20060760979P Applic. Date: 2006-01-20

Inventor: GAN DAVID [US]; HINES MICHELLE [US]; ARAVENA JAVIER [US]; JONES BRIAN [US]

Title: EXTERNAL PREPARATION COMPOSITION

Applicant/Assignee: LION CORPORATION

Application No.: 12/605294   Filing Date: 23/Oct/2009

Abstract:An external preparation composition used for preventing or treating symptoms or diseases related to dermatopathy caused by dryness, UV rays and aging such as wrinkles and sags of the skin, pigmentation of the skin, skin roughness and coarse texture and skin diseases such as psoriasis, lichen, ichthyosis, keratosis, Darier's disease, pustulosis, acne, eczema and atopic dermatitis. The external preparation composition comprises at least one of acyl glucosamine derivatives represented by the following Formula (I): wherein R1, R2, R3, R4 and R5 are defined

and X is any one of groups represented by the following Formulas (A) to (C): wherein Y, n and R6 are also defined.

Priority: US2008-257853 Applic. Date: 2008-10-24; US2005-522032 Applic. Date: 2005-01-21; WO2002JP07549 Applic. Date: 2002-07-25

Inventor: KAMBAYASHI HIROAKI [JP]; KONTA HIROSHI [JP]

Title: COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS

Applicant/Assignee:

Application No.: 12/565335   Filing Date: 23/Sep/2009

Abstract:The described invention relates to the formulation and delivery of compositions to treat an epithelial-related condition selected from the group consisting of sparse hair growth, short hair growth, thin hair growth, alopecia and hair depigmentation and methods for their use. In some embodiments, the composition contains a first component and a second component wherein the first component is at least one prostaglandin analog and the second component is at least one imidazole analog, such that the at least one imidazole analog improves the efficacy of the at least one prostaglandin analog when delivered to a subject refractory to the effect of the prostaglandin analog alone.

Priority: US20080099226P Applic. Date: 2008-09-23

Inventor: LIPKIN PAMELA [US]; LUBIT BEVERLY [US]

Title: SKIN CARE COMPOSITIONS AND RELATED METHODS

Applicant/Assignee:

Application No.: 11/996557   Filing Date: 22/Aug/2007

Abstract:A skin care composition comprising an acrylate polymer

a yield value increaser, and a surfactant. The composition has a yield value of at least about 4. Also included within the scope of the invention are related methods, such as methods of depositing a hydrophobic material on an epidermal surface and methods of incorporating a hydrophobic material into a skin care composition.

Priority: US2007-683801 Applic. Date: 2007-03-08; US20060823305P Applic. Date: 2006-08-23; WO2007US76494 Applic. Date: 2007-08-22

Inventor: HASKEL ARIEL [US]; PIMENTA PALOMA [US]

Title: COMPOSITION FOR IMPROVING SKIN QUALITY AND A PROCESS FOR PREPARING THE SAME

Applicant/Assignee: COMPAGNIE GERVAIS DANONE

Application No.: 12/445205   Filing Date: 12/Oct/2007

Abstract:The present invention relates to a composition including, as active substance, a mixture of at least one polyunsaturated fatty acid, different from polyunsaturated fatty acid derived from milk, polyphenols, milk proteins and lactic bacteria, and the composition having a water content of at least 50% by weight

and wherein the polyunsaturated fatty acid presents an increased bioavailability compared with the one of the polyunsaturated fatty acid alone.

Priority: EP20060291607 Applic. Date: 2006-10-13; WO2007EP60922 Applic. Date: 2007-10-12

Inventor: GUYONNET DENIS [FR]; LASSEL TAOUS [FR]; SAMSON-VILLEGER SANDRINE [FR]; TRGO CHRISTIAN [FR]; RAWLINGS ANTHONY [GB]

Title: SKIN AGENT FOR EXTERNAL USE AND COSMETIC AGENT INCLUDING UBIQUINONE DERIVATIVE OR SALT THEREOF AND METHOD USING THE SAME

Applicant/Assignee: SHOWA DENKO K.K

Application No.: 12/445184   Filing Date: 15/Oct/2007

Abstract:A skin agent for external use and a cosmetic agent are provided, by transdermal administration of which expected actions and effects of ubiquinone derivatives, salts thereof, ubiquinones and ubiquinols are effectively obtained. The skin agent for external use includes a ubiquinone derivative or a salt thereof as an active ingredient. The ubiquinone derivative is represented by the formula (1): wherein R1 and R2 are each a hydrogen atom or a phosphoric group, at least one of R1 and R2 is a phosphoric group, and n is an integer in the range of 1 to 9.

Priority: WO2007JP70385 Applic. Date: 2007-10-12; JP20060280112 Applic. Date: 2006-10-13; JP20070264317 Applic. Date: 2007-10-10

Inventor: AOKI HIROBUMI [JP]; KURATA YOHEI [JP]; KAMACHI HARUMI [JP]; NAKANISHI HIROTSUGU [JP]

Title: COSMETIC COMPOSITION COMPRISING A METEORITE EXTRACT, AND USE OF THE EXTRACT AS COSMETIC AGENT SUITABLE FOR STIMULATING THE DIFFERENTIATION OF HUMAN KERATINOCYTES

Applicant/Assignee: GATTEFOSSE SAS

Application No.: 12/418854   Filing Date: 06/Apr/2009

Abstract:The present invention relates to a cosmetic composition comprising a meteorite extract. The present invention also relates to methods of using the extract as a cosmetic agent suitable for stimulating the differentiation of human keratinocytes.

Priority: FR20080056344 Applic. Date: 2008-09-22

Inventor: ERISSON NEE CONRY MURIELLE [FR]; GUICHON ALAIN [FR]; LENNON PAULA [FR]

Title: METHOD AND APPARATUS FOR TEMPERING OF MEAT, TEMPERED MEAT TREATED BY THE METHOD, AND REFRIGERATED MEAT STORAGE

Applicant/Assignee: MAYEKAWA MFG. CO., LTD

Application No.: 12/563783   Filing Date: 21/Sep/2009

Abstract:A tempering treatment method whereby the temperature of meat, which involves carcass prepared by slaughtering cattle or poultry and sterilizing and washing, is lowered as close to the ice storage temperature as possible to prevent a temperature rise caused by the actions of enzymes contained within the meat before transporting the meant to a refrigerated storage, which comprises surface-freezing the meat by blowing a cold air stream at about -20 to about -40 DEG C. to the meant before conducting the tempering treatment, thus allowing the generation of freezing latent heat in the subcutaneous part owing to the surface-freezing (freezing the subcutaneous tissue), and then rapidly lowering the core temperature inside the meat due to the latent heat released at the melting of the freezing latent heat to thereby conduct the tempering treatment at a temperature of 0 to +15 DEG C.

Priority: WO2008JP54340 Applic. Date: 2008-03-11; US20070895886P Applic. Date: 2007-03-20

Inventor: OKAMOTO NAOTO [JP]; SAKURAMOTO SUGURU [JP]; ARAI TAKAHIRO [JP]; TSUBATA KOUICHI [JP]; TANIYAMA AKIRA [JP]

Title: METHODS FOR TREATING HERPES VIRUS INFECTIONS

Applicant/Assignee: NANOBIO CORPORATION

Application No.: 12/425984   Filing Date: 17/Apr/2009

Abstract:The present invention relates to methods for treating, killing, and/or inhibiting the growth of Herpes viruses in human subjects comprising topically administering to a human subject in need thereof a nanoemulsion composition having antiviral properties.

Priority: US20080046262P Applic. Date: 2008-04-18

Inventor: FLACK MARY R [US]; CIOTTI SUSAN MARIE [US]; HAMOUDA TAREK [US]; SUTCLIFFE JOYCE A [US]; BAKER JR JAMES R [US]

Title: USE OF EQUOL FOR TREATING SKIN DISEASES

Applicant/Assignee:

Application No.: 12/533169   Filing Date: 31/Jul/2009

Abstract:Equol (7-hydroxy-3(4'hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5[alpha]-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies of skin and hair. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes affecting skin and hair.

Priority: US2005-059951 Applic. Date: 2005-02-17; US2005-533045 Applic. Date: 2005-10-20; WO2003US34441 Applic. Date: 2003-10-29; US2003-625989 Applic. Date: 2003-07-24; US2008-167813 Applic. Date: 2008-07-03; US2003-625934 Applic. Date: 2003-07-24; US20040521457P Applic. Date: 2004-04-28; US20020422469P Applic. Date: 2002-10-29; US20020398270P Applic. Date: 2002-07-24

Inventor: LEPHART EDWIN DOUGLAS [US]; LUND TRENT D [US]; SETCHELL KENNETH DAVID REGINALD [US]; HANDA ROBERT J [US]

Title: ESTERS OF 4,5-DISUBSTITUTED-OXY-2-METHYL-3,6-DIOXO-CYCLOHEXA-1,4-DIENYL ALKYL ACIDS AND PREPARATION THEREOF

Applicant/Assignee: EASTMAN CHEMICAL COMPANY

Application No.: 12/236171   Filing Date: 23/Sep/2008

Abstract:Esters of 4,5-disubstituted-oxy-2-methyl-3,6-dioxo-cyclohexa-1,4-dienyl alkyl acids were prepared chemically and/or enzymatically. Depending upon the ester, improved melanocyte cytotoxicity was achieved. Improved cytotoxicity characteristics are consistent with ester analogs being more physiologically compatible and less irritating to skin than their corresponding acids.

Priority:

Inventor: WEMPE MICHAEL FITZPATRICK [US]; DENG LIU [US]; CLENDENNEN STEPHANIE KAY [US]; BOAZ NEIL WARREN [US]

Title: Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products

Applicant/Assignee:

Application No.: 12/541428   Filing Date: 14/Aug/2009

Abstract:The present invention provides synthetic routes for preparing various isomers of cyclohexane-based coolants, such as menthyl esters and menthanecarboxamide derivatives, in particular those substituted at the amide nitrogen, for example with an aromatic ring or aryl moiety. Such structures have high cooling potency and long lasting sensory effect, which make them useful in a wide variety of consumer products. One synthetic route involves a copper catalyzed coupling of a primary menthanecarboxamide with an aryl halide, such reaction working best in the presence of potassium phosphate and water. Using this synthetic route, specific isomers can be prepared including the menthanecarboxamide isomer having the same configuration as l-menthol and new isomers such as a neoisomer having opposite stereochemistry at the carboxamide (C-1) position. The neoisomer unexpectedly has potent and long lasting cooling effect. Preparation schemes for neoisomers of other menthyl derivatives which are useful as coolants, including esters, ethers, carboxy esters and other N-substituted carboxamides are also provided.

Priority: US20080089094P Applic. Date: 2008-08-15

Inventor: YELM KENNETH EDWARD [US]; BUNKE GREGORY MARK [US]; HAUGHT JOHN CHRISTIAN [US]

Title: ANTIMICROBIAL GEL FORMULATIONS

Applicant/Assignee: NOVABAY PHARMACEUTICALS, INC

Application No.: 12/540251   Filing Date: 12/Aug/2009

Abstract:Disclosed herein are formulations comprising an N-halogenated or N,N-dihalogenated amine compound dispersed in a water-swellable polymer, wherein the compound is 90% stable for at least 30 days at about 25 DEG C. Also disclosed are methods of treating or preventing infections caused by a bacterial, a microbial, a sporal, a fungal or a viral activity using such formulations.

Priority: US20080088302P Applic. Date: 2008-08-12; US20090229624P Applic. Date: 2009-07-29

Inventor: WANG LU [US]; NAJAFI AZAR [US]; MEMARZADEH BAHRAM [US]; SHARMA KULDEEPAK [US]; HO KIM PHUONG [US]

Title: Topical skin care formulations

Applicant/Assignee:

Application No.: 12/284398   Filing Date: 22/Sep/2008

Abstract:A topical anti-aging skin care formulation comprising an effective amount of a benzoquinone, such as CoQ10, plus a synergistic pair of stabilizers and a synergistic pair of whiteners. The stabilizers are octyl salicylate and octyl methoxycinnamate. The whiteners are titanium dioxide and zinc oxide. When proper amounts of these ingredients are used in an aqueous based emulsion formulation, the product will be initially white, and will remain white for an extended period of time.

Priority:

Inventor: HOLYFIELD LOUISE [US]

Title: Extracts of Isochrysis sp.

Applicant/Assignee: SYMRISE GMBH & CO. KG

Application No.: 12/568475   Filing Date: 28/Sep/2009

Abstract:The present invention relates to extracts of Isochrysis sp., preferably Tahitian Isochrysis, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Isochrysis sp., preferably Tahitian Isochrysis.

Priority: US20080101228P Applic. Date: 2008-09-30

Inventor: HERRMANN MARTINA [DE]; JOPPE HOLGER [DE]; PERTILE PAOLO [IT]; ZANELLA LORENZO [IT]

Title: SKIN CARE COMPOSITION

Applicant/Assignee:

Application No.: 12/440342   Filing Date: 05/Sep/2007

Abstract:The present invention relates to an oral composition containing an optimal combination of nutritional ingredients at high concentrations and at optimal ratios in order to maintain and/or achieve health and/or beautiful look of the skin.

Priority: EP20060018843 Applic. Date: 2006-09-08; EP20060026413 Applic. Date: 2006-12-20; WO2007EP07719 Applic. Date: 2007-09-05

Inventor: GORALCZYK REGINA [DE]

Title: ACRYLIC-BASED COPOLYMER COMPOSITIONS FOR COSMETIC AND PERSONAL CARE

Applicant/Assignee: 3M INNOVATIVE PROPERTIES COMPANY

Application No.: 12/632228   Filing Date: 07/Dec/2009

Abstract:A composition for nails, skin and hair in the form of an aqueous emulsion or dispersion is provided. The composition comprises: (a) at least one copolymer comprising (i) about 10 to 85 weight percent of (meth)acrylate ester of C4 to C18 straight and/or branched chain alkyl alcohol, (ii) about 10 to 70 weight percent of (meth)acrylate ester of a saturated or unsaturated cyclic alcohol containing 6 to 20 carbon atoms

and (b) an aqueous carrier, solvent, or vehicle component. When used in hair applications, the inventive composition is not a reshapable composition.

Priority: US2001-887751 Applic. Date: 2001-06-22; US2000-696468 Applic. Date: 2000-10-25

Inventor: KANTNER STEVEN S [US]; EVERAERTS ALBERT I [US]; NGUYEN LANG N [US]

Title: COMPOUNDS

Applicant/Assignee: CRODA UNIQEMA, INC

Application No.: 12/312430   Filing Date: 12/Nov/2007

Abstract:The present invention relates to compounds according to Formula 1

wherein R represents a hydrocarbon group, Z represents an oxyethylene group, B represents an alkyl chain comprising 1 to 5 carbon atoms, Y represents 0 or 1, X represents a number greater than zero, and their use as surfactants, and in particular as surfactants which act as foam promoting agents.

Priority: US20060858364P Applic. Date: 2006-11-13; WO2007US23844 Applic. Date: 2007-11-12

Inventor: QUEEN CRAIG BARTLETT [US]

Title: Compositions and Methods for the Treatment of Inflammatory Dermatosis and Other Pathological Conditions of the Skin

Applicant/Assignee:

Application No.: 12/238481   Filing Date: 26/Sep/2008

Abstract:The present invention relates to a composition used as a vehicle for percutaneous absorption of Pharmaceutical and Cosmaceutical active agents that comprises Dimethiconol (hydroxyl-terminated polydimethydimethylsiloxane), dimethicone-350 (polydimethylsiloxane-350), cyclomethicone-5 nf (decamethylcyclopentasiloxane), alkymeth siloxane copolyol-lauryl peg/ppg 18/18 methicone (alkymethyl siloxane copolyol), cyclopentasiloxane and dimethicone Crosspolymer (silicone elastomer and decamethylcyclopentasiloxane), stearoxytrimethylsilane and stearyl alcohol (silicone wax), and deionized water. This composition serves several key applications: (1) it is a vehicle for percutaneous absorption of Pharmaceutical and Cosmaceutical active agents

(2) it acts as a method for utilizing other compositions in the treatment of inflammatory conditions of the skin including, but by no means limited to, atopic dermatitis (eczema), allergic contact dermatitis, seborrheic dermatitits, psoriasis, xerosis and atopia

(3) it is a treatment of inflammatory conditions of mucosae

(4) it relates to other compositions and methods for protecting and enhancing the barrier function of the skin.

Priority:

Inventor: MCGRAW THOMAS L [US]; MCGRAW DONALD M [US]; MCGRAW KELI C [US]; MCGRAW DONALD V [US]

Title: Use of probiotic lactic acid bacteria for balancing the skin's immune system

Applicant/Assignee: NESTEC S.A

Application No.: 12/454722   Filing Date: 07/Aug/2009

Abstract:The present invention pertains to the use of probiotics for the preparation of a carrier for balancing the skin's immune function. In particular, the present invention pertains to the use of probiotic micro-organisms for balancing the skin's immune function under stress conditions, such as a exposure to ultraviolet radiation, specifically for enhancing the skin's immune activity and reducing the tendency to develop allergic reactions under such conditions.

Priority: EP20000121865 Applic. Date: 2000-10-06; US2003-381911 Applic. Date: 2003-08-12; WO2001EP11475 Applic. Date: 2001-10-04

Inventor: BAUR MARKUS [DE]; BRETON LIONEL [FR]; COUZY FRANCOIS [CH]; GUENICHE AUDREY [FR]

Title: Film Material With Antimicrobial And/Or Odor-Absorbing Coating and Sanitary Article

Applicant/Assignee: NUOVA PANSAC S.P.A

Application No.: 12/515191   Filing Date: 26/Jun/2009

Abstract:A film material (1) is disclosed herein, particularly a polyolefin-based film material, coated on one side with a water resoluble resin-containing skin (2), and containing antimicrobial and/or odor-absorbing agents susceptible of being activated by organic liquids and blood liquids, such film material is particularly designed to form a disposable sanitary article (4) comprising a liquid-pervious topsheet (5), a liquid-impervious backsheet (6) and an absorbent layer (7) sandwiched between the topsheet (5) and the backsheet (6).

Priority: IT2006MI02253 Applic. Date: 2006-11-24; WO2007IB03588 Applic. Date: 2007-11-22

Inventor: LORI FABRIZIO [IT]; DELLA ZASSA SANTE AURELIO [IT]

Title: Cosmetic Methods And Compositions For Repairing Human Skin

Applicant/Assignee:

Application No.: 12/631585   Filing Date: 04/Dec/2009

Abstract:The present invention relates to methods and compositions for repairing adverse effects of the environment, daily stress, sun exposure, or pre-mature aging on human skin, comprising applying to the skin, prior to a period of bodily rest, a topical composition that contains resveratrol or a derivative thereof and at least one DNA repair enzyme.

Priority: US2007-837658 Applic. Date: 2007-08-13

Inventor: MAES DANIEL H [US]; MAMMONE THOMAS [US]; GOLDGRABEN KERRI [US]

Title: Use of Spongilla Spicules as a Dermabrasion Device or Resurfacing Modality

Applicant/Assignee:

Application No.: 12/444495   Filing Date: 05/Oct/2007

Abstract:Dermabrasive compositions for skin resurfacing are disclosed. Therapeutic compositions disclosed are derived from Porifera species, specifically sponges, and more specifically fresh water sponges. One disclosed embodiment is derived from Spongilla species and is formulated with pharmaceutically acceptable excipients.

Priority: US20060828324P Applic. Date: 2006-10-05; WO2007US80587 Applic. Date: 2007-10-05

Inventor: VILLANI MARIA [US]

Title: COSMETIC OR DERMATOLOGICAL COMPOSITIONS COMPRISING A MIXTURE OF ESSENTIAL OILS, AND ITS USES THEREOF, PARTICULARLY FOR THE CARE OF SENSITIVE OR SENSITIZED SKIN

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/553200   Filing Date: 03/Sep/2009

Abstract:The present invention relates to cosmetic or dermatological compositions comprising a combination of a cannabis essential oil substantially free of cannabinoids and a helichrysum essential oil, and to their uses thereof, particularly for the care of sensitive or sensitized skin.

Priority: FR20080055994 Applic. Date: 2008-09-05

Inventor: ANDRE PATRICE [FR]; RENIMEL ISABELLE [FR]; JOLY FRANCINE [FR]

Title: TREATMENT AND COMPOSITION FOR ACHIEVING SKIN ANTI-AGING BENEFITS BY CORNEUM PROTEASE ACTIVATION

Applicant/Assignee: MARY KAY INC

Application No.: 12/632554   Filing Date: 07/Dec/2009

Abstract:Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.

Priority: US2008-202924 Applic. Date: 2008-09-02; US2007-624840 Applic. Date: 2007-01-19; US2002-273649 Applic. Date: 2002-12-12; US1999-357288 Applic. Date: 1999-07-20

Inventor: SCHILTZ JOHN R [US]

Title: METHOD OF EVALUATING ANTIWRINKLE SUBSTANCE AND METHOD OF ASSESSING THE SKIN

Applicant/Assignee: POLA CHEMICAL INDUSTRIES INC

Application No.: 12/529505   Filing Date: 18/Feb/2008

Abstract:It is intended to provide a method whereby the skin conditions (for example, loss in the skin elasticity, wrinkle formation possibility, insufficient tightness in dermal collagen fiber bundles, or the like) can be exactly and conveniently assessed. It is also intended to provide a method whereby the wrinkle-improvement effect of a test substance can be exactly and conveniently evaluated. The skin conditions are assessed by using the expression amount of an adhesion factor in skin cells as an indication. The wrinkle reducing effect of a test substance is evaluated by using the expression amount of an adhesion factor in skin cells in the presence of the test substance as an indication.

Priority: JP20070051025 Applic. Date: 2007-03-01; WO2008JP52626 Applic. Date: 2008-02-18

Inventor: KIDA NAOKO [JP]; TADA AKIHIRO [JP]

Title: Multifunctional telemetry alert safety system (MTASS)

Applicant/Assignee:

Application No.: 12/286210   Filing Date: 29/Sep/2008

Abstract:A personnel accountability and situational awareness monitoring communications system for emergency personnel that comprises wireless network-adaptable monitoring devices, peripherals and base station console software for telemetry monitoring of real-time information at a plurality of personnel accountability and situational awareness parameters of critical data about the safety, health and whereabouts of first responders deployed in typically hazardous environments. Exterior incident command, including fire, rescue, safety and other emergency agencies achieve real-time command view and control over a variety of personnel accountability and safety parameters during emergency response activities of personnel wearing the system of the present invention portable device while operating within the wireless network of an emergency incident scene. Configured to be carried by emergency services personnel while deployed on scene, the portable device is a multi-functional sensing and communicating integration of accountability and situational awareness technologies consolidated into one portable, telemetry device. The portable device's multifunctional integrated technology includes the monitoring, telemetry and alert notification of accountability identification, location, assignment notification, vital signs, ambient vicinity temperature, SCBA status, combustible gas sensing, video streaming, "evacuation" recall signaling, signal tracking and multi-alarm signaling if the wearer has either low remaining air pressure/time, impending thermal breakthrough, low battery power, exceeds the safety threshold for safe heart rate or external body temperature readings, or becomes motionless for a predetermined time period.

Priority:

Inventor: MONTENERO JOHN MATHEW [US]

Title: Eczema treatment with vitamin D and analogs thereof method, composition and cream

Applicant/Assignee: INNOVIA SKINCARE CORP

Application No.: 12/587070   Filing Date: 30/Sep/2009

Abstract:An eczema treatment method comprises application of a therapeutically effective composition in the form of an aqueous topical cream to an affected area of an exterior skin region of a patient, the aqueous topical cream comprising water, a water-soluble organic liquid, a surface active agent, and vitamin D3 compound or another claimed analog thereof, the vitamin D3 compound or the analog constituting at least approximately 10 international units per gram (IU/gram), and, most preferably at least approximately 400 IU/gram. An eczema treatment composition comprises a therapeutically effective formulation comprising at least approximately 50%-90% water, between approximately 1-5% PEG-40 stearate, between approximately 1-5% steareth-2, and cholecalciferal at a concentration of at least approximately 50 international units per gram (IU/g) of composition, and, most preferably at least approximately 400 IU/g. A topical vitamin D cream for therapeutic treatment of eczema includes vitamin D or an analog thereof chosen from the group consisting of cholecalciferol, alfacalcidol, calcifedol, and ergocalciferol

water

a water-soluble organic liquid

and a surface active agent, the vitamin D or analog being in a concentration of at least approximately 50 international units per gram (IU/g) of cream. Remarkably, relief from eczema conditions occurs immediately or in less than 3 days.

Priority: US20080194963P Applic. Date: 2008-10-01

Inventor: STRUBE MARILYN [US]

Title: PROCESS FOR PRODUCTION OF ETHER CARBOXYLATES

Applicant/Assignee: KAO CORPORATION

Application No.: 12/597019   Filing Date: 03/Apr/2008

Abstract:The present invention relates to a process for producing an ether carboxylate which includes the steps of (1) reacting an aliphatic monohydric alcohol with an alkylene oxide in the presence of an alkali catalyst

(2) neutralizing a reaction solution obtained in the step (1) with an acid such as hydroxycarboxylic acids to obtain an ether alcohol

and (3-1) reacting the obtained ether alcohol with a monohalogenofatty acid or a salt thereof and an alkali metal hydroxide, or (3-2) subjecting the obtained ether alcohol to catalytic oxidation reaction in the presence of a catalyst. The obtained ether carboxylate has a less odor and a high quality and is therefore suitably used in the applications such as cosmetics and toiletries.

Priority: JP20070122572 Applic. Date: 2007-05-07; WO2008JP56705 Applic. Date: 2008-04-03

Inventor: MATSUNAGA AKIRA [JP]; OHMAE KAORU [JP]

Title: DEVELOPMENTALLY DESIGNED DIAPER

Applicant/Assignee:

Application No.: 12/589514   Filing Date: 28/Apr/2009

Abstract:The present disclosure provides a developmentally designed diaper for LBW infants that is based on NIDCAP principals to allow for the proper positioning of a LBW infants limbs while wearing the diaper.

Priority: US20080127209P Applic. Date: 2008-05-09; US20080127210P Applic. Date: 2008-05-09; US20080127211P Applic. Date: 2008-05-09

Inventor: ROGONE MARY S [US]; ROGONE PHILIP N [US]; CROTEAU KENNETH S [US]; CROTEAU WINNIFRED D [US]

Title: Depilatory Composition

Applicant/Assignee: RECKITT & COLMAN (OVERSEAS) LIMITED

Application No.: 12/530426   Filing Date: 03/Mar/2008

Abstract:A depilatory cream composition comprising, a depilatory active, an emollient selected from at least one of mineral oil, silicone oil and emollient esters, and a silicone wax, a talc and/or polyamide resin.

Priority: GB20070004599 Applic. Date: 2007-03-09; WO2008GB00731 Applic. Date: 2008-03-03

Inventor: TINDAL ANNE [GB]; MANGASSI OUMOU [GB]

Title: SYSTEMS AND METHODS FOR DETECTING CHEMICAL AND BIOLOGICAL SUBSTANCES

Applicant/Assignee:

Application No.: 12/403522   Filing Date: 13/Mar/2009

Abstract:A method for detecting an ingredient in a food product or detecting a disease includes allowing a food sample solution obtained from a food product or a body fluid from an individual to come to contact with a nano-scale surface structure in a sensor, wherein the nano-scale surface structure comprises a plurality of columns over a substrate or a plurality of holes in a substrate. The method includes illuminating the food sample solution or the body fluid on the nano-scale surface structure on the sensor by a laser beam

obtaining a Raman spectrum from the scattered light using a spectral analyzer

and identifying the spectral signature in the Raman spectrum to determine the existence of the chemical substance in the food product or identifying a disease in the individual.

Priority: US2008-246616 Applic. Date: 2008-10-07

Inventor: GUO XUN [US]; WANG HONG [US]; LIU CHUNWEI [CN]

Title: SKIN TREATMENTS CONTAINING CARBOXYLIC ACID-SUBSTITUTED IDEBENONE DERIVATIVES AND METHODS OF PREPARATION AND USE THEREOF

Applicant/Assignee: PCR TECHNOLOGY HOLDINGS, LC

Application No.: 12/574135   Filing Date: 06/Oct/2009

Abstract:The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted idebenone derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change.

Priority: US20080103043P Applic. Date: 2008-10-06

Inventor: DIEDRICH FALKO [DE]; LEWIS II JOSEPH A [US]; DINARDO JOSEPH C [US]; NEUDECKER BIRGIT [DE]; WIELAND EBERHARD [DE]

Title: Personal Care Compositions Providing Enhanced Cooling Sensation

Applicant/Assignee:

Application No.: 12/636096   Filing Date: 11/Dec/2009

Abstract:Disclosed are personal care compositions for use on hair, skin, oral cavity, throat and other mucosal surfaces containing a flavor/perfume system comprising one or more coolants, wherein the pleasant cool and refreshing sensation provided by the coolant is enhanced in terms of quicker onset, greater intensity or impact and/or longer duration, thereby improving appeal and acceptability of the compositions to consumers. In one embodiment the invention provides oral care compositions comprising (a) a flavor composition comprising one or more non-menthol coolants and optionally one or more additional flavor ingredients, (b) a calcium ion source and/or a calcium transport agent sufficient to potentiate and/or modulate the cooling and refreshing sensation provided by the coolant(s), and (c) an orally-acceptable carrier. Upon application to the oral cavity, the compositions provide an immediate onset of cooling sensation which lasts longer than about 15 minutes thereby providing long-lasting clean and fresh mouth impression and encouraging user compliance and repeated use of the compositions.

Priority: US2008-274467 Applic. Date: 2008-11-20; US20070003863P Applic. Date: 2007-11-20

Inventor: HAUGHT JOHN CHRISTIAN [US]; GLANDORF WILLIAM MICHAEL [US]; JOHNSON CHRISTINE LULA [US]; SANKER LOWELL ALAN [US]

Title: Determining Age Ranges of Skin Samples

Applicant/Assignee: DERMTECH INTERNATIONAL

Application No.: 12/550060   Filing Date: 28/Aug/2009

Abstract:The present invention provides methods for characterizing a skin sample of a subject as belonging to an age range by analyzing nucleic acid or protein molecules obtained from the subject. The methods include analyzing expression or mutations in epidermal samples, of one or more skin markers. The methods can include the use of a microarray to analyze gene or protein profiles from a sample and compare them with a known skin age index. Therapeutic and cosmetic formulations are also provided herein.

Priority: US20080092687P Applic. Date: 2008-08-28

Inventor: CHANG SHERMAN H [US]; NAUGHTON GAIL K [US]

Title: METHODS OF ADMINISTERING TOPICAL ANTIFUNGAL FORMULATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS

Applicant/Assignee:

Application No.: 12/508537   Filing Date: 23/Jul/2009

Abstract:The present invention relates to topical antifungal formulations comprising one or more antifungal (e.g., terbinafine), a lipid and a surfactant, and uses thereof for the treatment of skin and nail fungal infections.

Priority: US20080083115P Applic. Date: 2008-07-23; US20080102111P Applic. Date: 2008-10-02; US20090150187P Applic. Date: 2009-02-05; US20090168122P Applic. Date: 2009-04-09

Inventor: CEVC GREGOR [DE]; VIERL ULRICH [DE]

Title: METHOD FOR PURPURA REDUCTION AND PREVENTION

Applicant/Assignee:

Application No.: 12/246528   Filing Date: 07/Oct/2008

Abstract:A method for reducing or eliminating skin discoloration caused by purpura or similar conditions uses corticosteroids, particularly glucocorticoids, in a long term cutaneous treatment. A cream, ointment, spray or other means is used to apply a glucocorticoid, for example, hydrocortisone to warmed skin having a red or purple discoloration. Application is continued daily for several months or years to reduce, eliminate and prevent discoloration.

Priority:

Inventor: BOVE ERNEST [US]

Title: MATERIAL, ITEM AND PRODUCTS COMPRISING A COMPOSITION HAVING ANTI-MICROBIAL PROPERTIES

Applicant/Assignee: NM TECH NANOMATERIALS MICRODEVICE TECHNOLOGY LTD

Application No.: 12/445307   Filing Date: 14/Oct/2009

Abstract:A coating product composition has the general formula AOx-(L-Men+)i, wherein AOx is a metal or metalloid oxide in which x indicates the number of the Oxygen atom(s) (O) bonded to the metal (A) atom, Men+ is a metal ion, L is a bifunctional molecule that could bind both metal oxide or metalloid oxide (AOx) and the metal ion (Men+), i is the number of the (L-Men+) groups bound to the metal oxide AOx. The value of the parameter i depends on various factors, such as the size of the nanoparticle of AOx, and the nature of the molecule L.

Priority: WO2006EP67361 Applic. Date: 2006-10-12

Inventor: BIGNOZZI CARLO ALBERTO [IT]; DISSETTE VALERIA [IT]

Title: METHODS FOR TREATING SKIN LESIONS

Applicant/Assignee:

Application No.: 12/575232   Filing Date: 07/Oct/2009

Abstract:The present invention relates to the treatment of skin lesions such as cold sores and other complications resulting from disorders such as herpes and the like. The invention relates to the use of a composition comprising one or more aluminum salts for treatment purposes.

Priority: US20080103854P Applic. Date: 2008-10-08

Inventor: ABUKURAH ABDUL R [US]

Title: Sensory Modifier

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 12/247478   Filing Date: 08/Oct/2008

Abstract:Sensory modifiers and compositions comprising sensory modifiers are described. The sensory modifiers comprise polysaccharide carbohydrate having at least about 75% by weight amylopectin and the polysaccharide carbohydrate has been treated and swollen with a substantially anhydrous solvent.

Priority:

Inventor: POLONKA JACK [US]

Title: Universal Sensory Structurant

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 12/247488   Filing Date: 08/Oct/2008

Abstract:Universal sensory structurants and compositions comprising the same are described. The universal sensory structurants comprise polysaccharide carbohydrate having at least about 75% by weight amylopectin and the polysaccharide carbohydrate has been treated and swollen with a solvent comprising hydroxylated polymer comprising less than about 100 silane repeat units.

Priority:

Inventor: POLONKA JACK [US]

Title: Compositions Containing Betaine and Hydrophobic Silica

Applicant/Assignee:

Application No.: 12/567002   Filing Date: 25/Sep/2009

Abstract:A free-flowing, substantially dry-to-the-touch, particulate composition comprises (A) finely particulate hydrophobic silicone-treated silica having a surface area of from 80 to 300 m2/g, (B) trimethylglycine, and (C) water, wherein the content of component (A) is greater than 2% and less than 8% by weight based on the total weight of components (A), (B) and (C) and wherein the content of component (B) is greater than 30% and less than 65% by weight based on the total weight of components (A), (B) and (C), said composition being in the form of particles of an aqueous solution of component (B) the surfaces of which particles are coated with a coating of component (A). The particulate composition is useful as a moisturising component in skin-care or cosmetic formulations.

Priority: US20080102777P Applic. Date: 2008-10-03

Inventor: TWYDELL ROLAND [GB]

Title: USE OF BIOTIN TO PREVENT PHOTOAGING

Applicant/Assignee:

Application No.: 12/597959   Filing Date: 07/May/2008

Abstract:Use of biotin, preferably in a combination of biotin and (-)-epigallocatechin gallate (EGCG) in a specific ratio, to prevent sunlight-induced aging (photoaging) of the skin.

Priority: EP20070009371 Applic. Date: 2007-05-10; WO2008EP03648 Applic. Date: 2008-05-07

Inventor: GORALCZYK REGINA [DE]; SCHWAGER JOSEPH [CH]

Title: Systems and Methods for Optimization of Sleep and Post-Sleep Performance

Applicant/Assignee: ADVANCED BRAIN MONITORING, INC

Application No.: 12/574631   Filing Date: 06/Oct/2009

Abstract:Systems and methods for optimizing the sleep and post-sleep performance of individuals regardless of their environment and time available for sleep are provided. The systems and methods take into account factors that determine the effects of a sleep episode on dexterity, cognitive functions and the subjective feeling of fatigue after sleeping: duration and sleep architecture of the sleep episode, point on the circadian cycle at which the episode occurred, the amount of sleep debt accumulated prior to the episode and the subject's susceptibility to sleep deprivation. The systems and methods include monitoring of sleep architecture over a longer period of time, measurement of accumulated sleep debt and assessment and/or tailoring of the sleep architecture for each subsequent sleep episode, determining a desired sleep state in which the subject should be in, and generating sensory stimuli for guiding the subject to the desired sleep state.

Priority: US20080103512P Applic. Date: 2008-10-07

Inventor: BERKA CHRIS [US]; POPOVIC DJORDJE [US]; DAVIS GENE [US]; YANAGI MATTHEW A [US]

Title: IMMUNE RESPONSE MODIFIER FORMULATIONS

Applicant/Assignee: GRACEWAY PHARMACEUTICALS, LLC

Application No.: 12/309367   Filing Date: 12/Jul/2007

Abstract:The present invention provides a pharmaceutical foam formulation. Generally, the formulation includes a therapeutically effective amount of imiquimod and a fatty acid.

Priority: US20060807669P Applic. Date: 2006-07-18; WO2007US16029 Applic. Date: 2007-07-12

Inventor: VALLEJO JANET A [US]; LEUNG SUZANNE S [US]; RODDY PATRICK J [US]; BUSCH TERRI F [US]

Title: HYDROGENATION OF CARYOPHELLENE

Applicant/Assignee: E.I. DU PONT DE NEMOURS AND COMAPNY

Application No.: 12/519614   Filing Date: 20/Dec/2007

Abstract:A process for the hydrogenation of a mixture of caryophyllenes by contact with hydrogen in the presence of a supported catalyst. The resulting products are useful for the application to skin.

Priority: US20060876555P Applic. Date: 2006-12-21; WO2007US25983 Applic. Date: 2007-12-20

Inventor: HUTCHENSON KEITH W [US]; JACKSON SCOTT CHRISTOPHER [US]; MANZER LEO ERNEST [US]; SCIALDONE MARK A [US]; SEAPAN MAYIS [US]

Title: RESILIENT PERSONAL CARE COMPOSITION COMPRISING POLYALKYL ETHER CONTAINING SILOXANE ELASTOMERS

Applicant/Assignee:

Application No.: 12/251154   Filing Date: 14/Oct/2008

Abstract:A stable personal care composition in the form of a water-in-oil emulsion may comprise a silicone elastomer comprising a polyalkyl ether pendant or a polyalkyl ether crosslink, wherein the alkyl group contains three or more carbon atoms

a non-emulsifying silicone elastomer

an emulsifier

a polar oil

and water. The personal care composition allows for previously unattainable levels of polar oils and/or aqueous phase within a water-in-oil emulsion.

Priority:

Inventor: BREYFOGLE LAURIE ELLEN [US]; TANNER PAUL ROBERT [US]; AISTRUP ELIZABETH REBECCA [US]

Title: PERSONAL CARE COMPOSITIONS COMPRISING MODIFIED VARIANT BOWMAN BIRK PROTEASE INHIBITORS

Applicant/Assignee: DANISCO US INC

Application No.: 12/252032   Filing Date: 15/Oct/2008

Abstract:The present invention relates to compositions that comprise modified variant Bowman Birk Protease Inhibitor proteins (BBPIs). The modified variant BBPIs comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses the compositions comprising the modified variant BBPIs, and the methods for making and using the compositions in personal care.

Priority:

Inventor: AMIN NEELAM S [US]; COLLIER KATHERINE D [US]; ESTABROOK MELODIE [US]; ESTELL DAVID A [US]; FOX BRYAN P [US]; POWER SCOTT D [US]; SCHMIDT BRIAN F [US]; VOGTENTANZ GUDRUN [US]

Title: SELF TANNING COMPOSITIONS CONTAINING DIHYDROXYACETONE, A RETINOID AND ASCORBIC ACID GLUCOSIDE AS A STABILIZER

Applicant/Assignee:

Application No.: 12/576382   Filing Date: 09/Oct/2009

Abstract:The invention concerns a composition comprising dihydroxyacetone, a retinoid and a glycosylated ascorbic acid.

Priority: EP20080305675 Applic. Date: 2008-10-13

Inventor: GOHIER ANNIE [FR]; JOETZJER PASCALE [FR]; MARCHELIDON HERVE [FR]

Title: Guar Protein Extracts and Compositions Comprised Thereof as Surface Treating and/or Modifying Agents

Applicant/Assignee: RHODIA CHIMIE

Application No.: 11/989997   Filing Date: 07/Aug/2006

Abstract:Surface treating and/or modifying compositions, for example cosmetic or pharmaceutical or plant protective compositions or domestic care compositions contain a guar protein extract, or derivative thereof, such guar protein extract containing at least 65% by weight of proteins and are particularly suitable as surface treating and/or modifying agents, wherein these surfaces are, for example, the skin, hairs, domestic care and textile surfaces and plant leaf surfaces.

Priority: FR20050008381 Applic. Date: 2005-08-05; WO2006FR01914 Applic. Date: 2006-08-07

Inventor: KARAGIANNI KATERINA [FR]; MONIN VINCENT [US]; SASSI JEAN-FRANCOIS [FR]

Title: NOVEL USE OF ANTIDEPRESSANT COMPOUNDS AND RELATED COMPOSITIONS

Applicant/Assignee:

Application No.: 12/520503   Filing Date: 20/Dec/2007

Abstract:What is described is a use of an antidepressant compound, preferably belonging to the class of selective serotonin reuptake inhibitors (SSRI), for regenerating the integumentary system and/or for stimulating the growth, the original trophism and/or original pigmentation of the corresponding cutaneous appendages, particularly body hair and/or head hair, in mammals. For this purpose, the antidepressant can be formulated in a cosmetic preparation, a pharmaceutical composition, a medical device, or in the form of a culture medium, alone or in combination with a further active ingredient such as a proteolytic enzyme and/or a vitamin.

Priority: IT2006TO00918 Applic. Date: 2006-12-22; IT2006TO00920 Applic. Date: 2006-12-22; IT2007TO00603 Applic. Date: 2007-08-20; WO2007IT00891 Applic. Date: 2007-12-20

Inventor: DE VIVO ENRICO [IT]; PONZETTO ANTONIO [IT]; CESANO CHIARA [IT]; GENNERO LUISA [IT]; MERIZZI GIANFRANCO [IT]; MORRA EMANUELLA [IT]

Title: USE OF PHAEODACTYLUM ALGAE EXTRACT FOR DEPIGMENTING THE SKIN

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/530266   Filing Date: 07/Mar/2008

Abstract:The invention relates to the use in a cosmetic composition of an extract of the alga Phaeodactylum tricornutum, as a depigmenting active agent intended in particular for attenuating or eliminating skin pigmentation marks or for lightening the complexion or bodily hairs or head hair. The extract is preferably a lipid extract. The invention also relates to a cosmetic care method for attenuating or eliminating skin pigmentation marks or for lightening the complexion or bodily hairs or head hair, characterized in that it comprises the application, to at least one concerned area of the skin, of a cosmetic composition containing this extract.

Priority: FR20070053728 Applic. Date: 2007-03-08; WO2008FR50394 Applic. Date: 2008-03-07

Inventor: NIZARD CARINE [FR]; MOREAU MARIELLE [FR]; KURFURST ROBIN [FR]; FRIGUET BERTRAND [FR]; BULTEAU ANNE-LAURE [FR]; GAREIL MONIQUE [FR]

Title: Topical and Transdermal Delivery of HIF-1 Modulators to Prevent and Treat Chronic Wounds

Applicant/Assignee:

Application No.: 12/577006   Filing Date: 09/Oct/2009

Abstract:Compositions and methods are provided for the treatment of chronic wounds, including, without limitation, pressure ulcers and diabetic ulcers, by transdermal delivery of an agent that increases activity of HIF-1[alpha] in the wound. Agents that increase HIF-1[alpha] activity include, without limitation, agents that stabilize HIF-1[alpha], e.g. deferoxamine, deferiprone, deferasirox, etc.

agents that upregulate expression of HIF-1[alpha], e.g. dimethyloxalylglycine, etc., HIF-1[alpha] polypeptide or coding sequences

and combinations thereof. Such agents may be referred to herein as HIF-1[alpha] potentiating agents.

Priority: US20080104599P Applic. Date: 2008-10-10

Inventor: GURTNER GEOFFREY C [US]; RAJADAS JAYAKUMAR [US]; GALVEZ MICHAEL GABRIEL [US]; NEOFYTOU EVGENIOS [US]

Title: TOPICAL COMPOSITIONS CONTAINING MAGALDRATE

Applicant/Assignee:

Application No.: 12/593299   Filing Date: 28/Mar/2008

Abstract:Disclosed are topical compositions containing the active ingredient magaldrate mixed with suitable vehicles and excipients.

Priority: IT2007MI00644 Applic. Date: 2007-03-29; WO2008IB02047 Applic. Date: 2008-03-28

Inventor: GUASTI PIER LUIGI [SM]

Title: PLANT EXTRACTION METHOD AND COMPOSITIONS

Applicant/Assignee: NERIUM BIOTECHNOLOGY, INC

Application No.: 12/578436   Filing Date: 13/Oct/2009

Abstract:The present invention pertains to methods of extracting cardiac glycosides from cardiac glycoside containing plant material, such as Nerium oleander, through use of aloe. It further provides for compositions resulting from such extractions, pharmaceutical compositions, cosmetic compositions, and methods of treating skin conditions.

Priority: US20080105133P Applic. Date: 2008-10-14

Inventor: SMOTHERS DONALD L [US]

Title: METHOD FOR USING HYDROPHOBICALLY MODIFIED POLYMERS IN CONSUMER AND INDUSTRIAL APPLICATIONS

Applicant/Assignee:

Application No.: 12/575966   Filing Date: 08/Oct/2009

Abstract:This invention pertains to method of using a composition comprising one or more hydrophobically modified polyacrylamides, wherein the polyacrylamides contain acrylamide, one or more anionic monomers, and excludes a cationic monomer, and the method of combination with other compositions for use in combination for consumer and/or industrial applications.

Priority: US2007-853084 Applic. Date: 2007-09-11

Inventor: HESSEFORT YIN Z [US]; MAREK PATRICK J [US]; CRAMM JEFFREY R [US]; PATEL DAMYANTI J [US]; CARLSON WAYNE M [US]

Title: Cleansing Formulations Comprising Non-Cellulosic Polysaccharide With Mixed Cationic Substituents

Applicant/Assignee: HERCULES INCORPORATED

Application No.: 12/576639   Filing Date: 09/Oct/2009

Abstract:The present invention is related to the use of a non-cellulosic cationically modified polysaccharide in cleaning compositions and more particularly to a surfactant based cleansing composition comprising, a surfactant, a non-cellulosic cationically modified polysaccharide and a solvent for use in personal care composition, household care composition or an institutional care composition.

Priority: US20080195698P Applic. Date: 2008-10-09

Inventor: BRAND PIET [NL]; BROWN RICHARD G [US]; CHAN ANITA N [US]; ERAZO-MAJEWICZ PAQUITA [US]; MODI JASHAWANT J [US]

Title: PEPTIDES AND USE THEREOF

Applicant/Assignee:

Application No.: 12/089300   Filing Date: 10/Oct/2006

Abstract:The present invention relates to peptides, compositions containing such peptides, and the use thereof. The peptides derived from C-krox binding sequences of three zinc finger domains are effective for stimulating the collagen synthesis of normal human dermal fibroblast, and thus can be used to improve the appearance of the skin.

Priority: EP20050292121 Applic. Date: 2005-10-11; WO2006EP09756 Applic. Date: 2006-10-10

Inventor: ODDOS THIERRY [FR]; BELLEMERE GAELLE [FR]; VON STETTEN OTTO [DE]

Title: Skin cancer prevention method and product

Applicant/Assignee:

Application No.: 11/196946   Filing Date: 04/Aug/2005

Abstract:The increased use of sunscreens, while limiting damage to the DNA, may promote cancer growth by preventing vitamin D synthesis in the skin. According to the present invention, the beneficial effects of UV radiation are obtained by incorporating vitamin D into the topical after-sun lotions and creams, applied to the skin after exposure to the sun to prevent its harmful effects. Application of the after-sun product provides vitamin D, which is activated by the skin to calcitriol for cancer prevention. Because calcitriol also promotes cellular growth and differentiation, the topical after-sun product with vitamin D may be of benefit for photoaging.

Priority:

Inventor: PERSON JOHN R [US]

Title: TOPICAL FORMULATIONS

Applicant/Assignee: HELPERBY THERAPEUTICS LIMITED

Application No.: 12/513783   Filing Date: 08/Nov/2007

Abstract:There is provided topical pharmaceutical compositions comprising compounds of formula I wherein R1, R2, R3 and X have meanings given in the description. These compositions can be used to treat microbial infections and to kill clinically latent microorganisms.

Priority: WO2006GB04178 Applic. Date: 2006-11-08; GB20070009513 Applic. Date: 2007-05-17; WO2007GB04268 Applic. Date: 2007-11-08

Inventor: BECK PETRA HELGA [GB]; BROWN MARC BARRY [GB]; COATES ANTHONY [GB]; HU YANMIN [GB]; STODDART GERLINDA [GB]

Title: STEROIDAL COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF

Applicant/Assignee:

Application No.: 12/433322   Filing Date: 30/Apr/2009

Abstract:A method for the identification of compounds) that control melanin synthesis (melanogenesis), and the preparation and use of such compounds, and compositions and formulations thereof to modify (e.g., inhibit) melanin production are disclosed. A representative compound of the invention is defined by formula I: The compounds may be prepared as pharmaceutical and cosmetic compositions, and in one embodiment, may be prepared in combination with each other, and with other melanogenesis inhibiting formulations. The compounds, compositions and formulations of the invention may be used for the prevention and treatment of conditions that are causally related to aberrant melanogenesis activity including, by way of non-limiting example, hyperpigmentation and others.

Priority: US20080049114P Applic. Date: 2008-04-30

Inventor: ORLOW SETH J [US]; KOMATSU LI NI [US]

Title: METHOD FOR TOPICAL TREATMENT OF TAR-RESPONSIVE DERMATOLOGICAL DISORDERS

Applicant/Assignee: TRISTRATA, INC

Application No.: 12/638505   Filing Date: 15/Dec/2009

Abstract:A method of treating a tar-responsive dermatological disorder includes topically applying an anhydrous tar composition to skin of a mammal, preferably a human, that is involved with the disorder, the composition including a wax and a therapeutically effective amount of tar for topical treatment of the tar-responsive dermatological disorder, the composition being in liquid form when at a temperature selected from room temperature and a temperature of skin of a mammal upon application of the composition to the skin of the mammal.

Priority: US2007-680227 Applic. Date: 2007-02-28; US20060778128P Applic. Date: 2006-03-01

Inventor: YU RUEY J [US]; VAN SCOTT EUGENE J [US]; LEE YALING [US]

Title: COMPOSITION FOR EXTERNAL APPLICATION TO SKIN

Applicant/Assignee: SHISEIDO COMPANY LTD

Application No.: 12/449143   Filing Date: 24/Jan/2008

Abstract:The present invention provides a composition for external application to skin containing one type or two or more types of compounds selected from the group consisting of aminoacetoamide compounds represented by the following general formula (1) and salts thereof.

Priority: JP20070015083 Applic. Date: 2007-01-25; WO2008JP51000 Applic. Date: 2008-01-24

Inventor: KAMINUMA MIKIKO [JP]; SUETSUGU MASARU [JP]; OCHIAI NOBUHIKO [JP]; TSUNENAGA MAKOTO [JP]

Title: METHOD FOR BREEDING TOMATOES HAVING REDUCED WATER CONTENT AND PRODUCT OF THE METHOD

Applicant/Assignee: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O.), VOLCANI CENTER

Application No.: 12/636880   Filing Date: 14/Dec/2009

Abstract:A method for breeding tomato plants that produce tomatoes with reduced fruit water content including the steps of crossing at least one Lycopersicon esculentum plant with a Lycopersicon spp. to produce hybrid seed, collecting the first generation of hybrid seeds, growing plants from the first generation of hybrid seeds, pollinating the plants of the most recent hybrid generation, collecting the seeds produced by the most recent hybrid generation, growing plants from the seeds of the most recent hybrid generation, allowing plants to remain on the vine past the point of normal ripening, and screening for reduced fruit water content as indicated by extended preservation of the ripe fruit and wrinkling of the fruit skin.

Priority: IL19990131509 Applic. Date: 1999-08-19; US2006-506896 Applic. Date: 2006-08-21; US2002-069389 Applic. Date: 2002-06-27; WO2000IL00389 Applic. Date: 2000-07-04

Inventor: SCHAFFER ARTHUR A [IL]

Title: SOLUBILIZING SYSTEMS FOR FLAVORS AND FRAGRANCES

Applicant/Assignee: FIRMENICH SA

Application No.: 12/643269   Filing Date: 21/Dec/2009

Abstract:The present invention provides compositions and clear oil-in-water microemulsion containing up to 80% w/w of an oil, a surfactant system, a w/w oil/surfactant system ratio between 1 and 3, and a solubilizing-aid ingredient which is not a surfactant neither a VOC compound, the latter being present in an amount sufficient to ensure that the ratio oil/(surfactant+solubilizing aid) is comprised between 0.1 and 5. The present invention concerns also the articles and products associated the compositions and microemulsions, and the methods to manufacture them.

Priority: EP20040105185 Applic. Date: 2004-10-20; US2007-689635 Applic. Date: 2007-03-22; WO2005IB03329 Applic. Date: 2005-10-19; US2005-245704 Applic. Date: 2005-10-06; WO2004IB01473 Applic. Date: 2004-04-19; US2003-421216 Applic. Date: 2003-04-21; US20040620557P Applic. Date: 2004-10-20

Inventor: VLAD FLORIN JOSEPH [US]; MOUNIER REMY [FR]; WONG KENNETH [CH]; DAUGERON AUDE [FR]; HERD THOMAS [US]

Title: Soap-Based Liquid Wash Formulations with Enhanced Deposition of Conditioning and/or Skin Appearance Enhancing Agents

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 12/255349   Filing Date: 21/Oct/2008

Abstract:The invention relates to soap-based liquid body and facial wash compositions. Using high solvent, low water compositions and incompletely naturalized fatty acids to help structure the compositions, all in combination with modified benefit agents, enhanced deposition of conditioning and/or skin appearance and/or optical enhancing agents is achieved.

Priority:

Inventor: CARNALI JOSEPH ORESTE [US]; SHAH PRAVIN [US]; QIU QIANG [US]

Title: Soap-Based Liquid Wash Formulations with Enhanced Deposition of Make-Up Agents

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 12/255365   Filing Date: 21/Oct/2008

Abstract:The invention relates to soap based liquid body and facial wash compositions. Using high solvent, low water compositions and incompletely neutralized fatty acid to help structure the compositions, all in combination with modified benefit agents, enhanced deposition of make-up agents is achieved.

Priority:

Inventor: CARNALI JOSEPH ORESTE [US]; SHAH PRAVIN [US]; QIU QIANG [US]; LIPS ALEXANDER [GB]

Title: COMPOSITIONS CONTAINING AT LEAST ONE OIL STRUCTURED WITH AT LEAST ONE SILICONE-POLYAMIDE POLYMER, AND AT LEAST ONE CRYSTALLINE SILICONE COMPOUND AND METHODS OF USING THE SAME

Applicant/Assignee: L'OREAL

Application No.: 12/648020   Filing Date: 28/Dec/2009

Abstract:The invention relates to a physiologically acceptable composition, in particular a cosmetic composition, containing at least one liquid fatty phase structured with at least one structuring polymer of the silicone-polyamide type, the polymer being solid at room temperature and soluble in the liquid fatty phase at a temperature of from 25 to 250 DEG C., and at least one crystalline silicone compound, said oil having an affinity with said structuring polymer and/or with said crystalline silicone compound, and the liquid fatty phase, the polymer and the crystalline silicone compound forming a physiologically acceptable medium. This composition may be in the form of a stick of lipstick which is stable, which does not exude and whose application produces a glossy deposit with good staying power over time.

Priority: US2002-320601 Applic. Date: 2002-12-17

Inventor: YU WEI [US]

Title: PROMOTION OF PEROXISOMAL CATALASE FUNCTION IN CELLS

Applicant/Assignee: WAYNE STATE UNIVERSITY

Application No.: 12/568960   Filing Date: 29/Sep/2009

Abstract:The molecular mechanisms of peroxisome biogenesis have begun to emerge

in contrast, relatively little is known about how the organelle functions as cells age. The present inventors characterized age-related changes in peroxisomes of human cells and showed that aging compromises peroxisomal targeting signal 1 (PTS1) protein import, with the critical antioxidant enzyme, catalase, especially affected. The number and appearance of peroxisomes are altered in these cells, and the organelles accumulate the PTS1-import receptor, Pex5p, on their membranes. Concomitantly, cells produce increasing amounts of the toxic metabolite, H2O2, and this increased load of reactive oxygen species (ROS) may further reduce peroxisomal protein import and exacerbate the effects of aging. Disclosed are novel compositions and methods for restoring catalase in peroxisomes by use of targeted catalase modified at its C-terminus and/or N-terminus, optionally in combination with polypeptides which promote cellular uptake of proteins, to prevent or overcome the changes that follows aging or that are associated with a number of diseases or disorders.

Priority: US2005-533124 Applic. Date: 2005-12-27; WO2003US34512 Applic. Date: 2003-10-30; US20020422100P Applic. Date: 2002-10-30

Inventor: TERLECKY STANLEY R [US]; WALTON PAUL A [CA]

Title: METHODS, PROCESSES AND COMPOSITIONS COMPRISING THE PROTEIN CALMODULIN (CAM) FOR TREATMENT OF DAMAGED OR AGING SKIN, AND/OR HAIR LOSS

Applicant/Assignee:

Application No.: 12/449916   Filing Date: 21/Mar/2007

Abstract:The invention relates to compositions comprising the calcium binding protein, calmodulin (CaM), and the use of this protein additive in compositions suitable for topical application for the maintenance and development of healthy skin

for improving the aesthetic appearance of skin

for treating fine lines, and/or wrinkles, and/or age spots, and/or minor wounds and burns, and/or calloused skin-through its facilitation of natural healing processes initiated by disease, injury or aging

for enhancing hair growth

and as a cosmetic treatment process comprising application to the skin the compositions, preferably on a daily basis. The compositions may comprise, but not be limited to, UV blocking agents and/or penetration enhancers and/or one or more bio-active agents. CaM can be formulated into therapeutic compositions as lotions, creams, ointments, sprays, gels, skin coverings and wound dressings.

Priority: WO2007IB02725 Applic. Date: 2007-03-21

Inventor: TIPPENS DORR FELT [US]

Title: METHODS FOR PREPARATION OF A THIXOTROPIC MICROEMULSION FOR SKIN CARE FORMULATIONS

Applicant/Assignee:

Application No.: 12/619982   Filing Date: 17/Nov/2009

Abstract:Methods for the preparation of a novel topical gel delivery system are disclosed. The delivery system is an oil-in-water (O/W) type thixotropic microemulsion especially useful as a vehicle for the delivery of botanical actives. The delivery system is comprised of natural starches emulsified with a cationic surfactant and utilizes both synthetic and cosmetically-acceptable oils in a two step process. The resulting microemulsion is a uniform dispersion of oil droplets in a stable starch-oil composite. The method also allows for sequestering volatile fragrances by encapsulating them in the oil phase droplets, drying of liquid emulsions to a thin film, and subsequent moisture-activated release of the entrapped fragrances from dried films. Finally, a wound dressing that undergoes reversible hydration upon contact with wound exudates can be prepared by the methods of this invention.

Priority: US2004-873590 Applic. Date: 2004-06-22; US2006-339419 Applic. Date: 2006-01-25; US20030485058P Applic. Date: 2003-07-07; US20050646896P Applic. Date: 2005-01-25

Inventor: WILLE JR JOHN JACOB [US]

Title: Novel Use Of An Extract Of Common Mallow As An Hydrating Agent, And Cosmetic Composition Containing It

Applicant/Assignee: LVMH RECHERCHE

Application No.: 12/500824   Filing Date: 10/Jul/2009

Abstract:The present invention relates to a novel use of an extract of common mallow for restoring, maintaining or reinforcing the state of moisturization of the skin

to a cosmetic composition containing it, and also to cosmetic care methods using said composition.

Priority: FR20080054780 Applic. Date: 2008-07-11

Inventor: DUMAS MARC [FR]; NOBLESSE EMMANUELLE [FR]; KRZYCH VALERIE [FR]; CAUCHARD JEAN HUBERT [FR]

Title: Materials and Methods for Delivering Antioxidants into the Skin

Applicant/Assignee:

Application No.: 12/523237   Filing Date: 18/Jan/2008

Abstract:Compositions and methods for administering one or more antioxidants to a human subject have been developed. The antioxidant-containing lipid vesicles of the invention provide a delivery system for antioxidants which can be applied topically to the skin.

Priority: US20070885643P Applic. Date: 2007-01-19; US20070885641P Applic. Date: 2007-01-19; US20070885551P Applic. Date: 2007-01-18; US20070885549P Applic. Date: 2007-01-18; US20070885523P Applic. Date: 2007-01-18; US20070885482P Applic. Date: 2007-01-18; WO2008US51437 Applic. Date: 2008-01-18

Inventor: PINSKY MARK A [US]

Title: Powder Makeup Compositions And Methods

Applicant/Assignee:

Application No.: 12/255975   Filing Date: 22/Oct/2008

Abstract:An anhydrous powder composition wherein the ratio of platelet to non-platelet particulates is greater than about 5 to 1 respectively, which is preferably talc-free, oil-free, paraben-free, and fragrance-free

and a method for preparing the powder composition of the invention.

Priority:

Inventor: MERCADO CLARA G [US]; LOGALBO JOHN F [US]; DAO KHANH NGOC [US]

Title: Synthetic Peptides Reducing or Removing Bags Formed Under the Lower Eye Contour and Their Use in Cosmetic or Dermopharmaceutical Compositions

Applicant/Assignee: LIPOTEC, S.A

Application No.: 11/664574   Filing Date: 22/Sep/2005

Abstract:The invention relates to peptides of general formula (I): that can reduce or remove bags formed under the eyes, their stereoisomers and racemic or non-racemic mixtures thereof, and the cosmetically or dermopharmaceutically acceptable salts thereof, wherein X is cystenyl, seryl, threonyl or aminobutyryl

R1 is H or alkyl, aryl, aralkyl or acyl group

and R2 is amino, hydroxy or thiol, all of them substituted or non-substituted with aliphatic or cyclic groups. The invention also relates to a method of obtaining, cosmetic or dermopharmaceutical compositions containing them and their use for treating skin, preferably for reducing or removing bags formed under the eyes.

Priority: ES20040002364 Applic. Date: 2004-10-05; WO2005ES00514 Applic. Date: 2005-09-22

Inventor: PUIG MONTIEL ARTURO [ES]; CEBRIAN PUCHE JUAN [ES]; PASSERINI ELENA [ES]

Title: SOAP-BASED LIQUID WASH FORMULATIONS WITH ENHANCED DEPOSITION OF ANTIMICROBIAL AGENTS

Applicant/Assignee: CONOPCO, INC., D/B/A UNILEVER

Application No.: 12/255377   Filing Date: 21/Oct/2008

Abstract:The invention relates to soap-based liquid body and facial wash compositions using high solvent, low water compositions and incompletely neutralized fatty acids to help structure the compositions, all in combination with modified benefit agents, enhanced deposition of antimicrobial agents is obtained.

Priority:

Inventor: CARNALI JOSEPH ORESTE [US]; SHAH PRAVIN [US]; QIU QIANG [US]; WEIR ANTHONY JOHN [US]

Title: Composition of Ashwagandha and Indian Gooseberry

Applicant/Assignee: NUTRAGENESIS, LLC

Application No.: 12/604092   Filing Date: 22/Oct/2009

Abstract:A therapeutic composition comprising extracts of the plant species ashwagandha (Withania somnifera) and Indian gooseberry (Phyllanthus emblica). A composition of ashwagandha and Indian gooseberry may: (1) lower cortisol and increase DHEA, (2) prevents free radical-induced photoaging, (3) inhibit collagenase activity in vitro, (4) inhibit hyaluronidase activity in vitro, (5) display superior cascading antioxidant activity, (6) reduce C-reactive protein, (7) enhance mood.

Priority: US20080107573P Applic. Date: 2008-10-22

Inventor: MCNEARY PETER [US]

Title: Topical anti-wrinkle and anti-aging moisturizing cream

Applicant/Assignee:

Application No.: 12/589088   Filing Date: 19/Oct/2009

Abstract:The present invention relates to a topical anti-wrinkle and anti-aging moisturizing cream designed (formulated) to repair and restore human adult skin to its original youthful state. This has successfully been achieved by using a water based molecular mixture of high molecular weight (0.5 to 2.0 million Daltons) hyaluronic acid (HA) and of low molecular weight hyaluronic acid oligosaccharides (small HA fragments less than 12000 Daltons molecular weight) to create this unique anti-aging moisturizer. An equal mixture of high molecular HA and HA-oligosaccharides at concentrations of 0.1-0.2% was found to be essential for providing our moisturizer its unique ability to repair and rejuvenate adult human skin.

Priority: US20080106413P Applic. Date: 2008-10-17

Inventor: ARMAND GERARD [US]

Title: Fragrance-delivery composition comprising boron and persulfate ion-crosslinked polyvinyl alcohol microcapsules and method of use thereof

Applicant/Assignee:

Application No.: 12/289010   Filing Date: 17/Oct/2008

Abstract:An aqueous composition is provided having a pH of from about 2.0 to about 5.7 to about 12.8 and comprising boron or persulfate ion-crosslinked polyvinyl alcohol microcapsules. A method of delivering a fragrance to a substrate is further provided comprising applying to the substrate an aqueous composition comprised of fragrance-containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules, as well as a method of cleaning a substrate comprising applying to the substrate an aqueous composition comprised of fragrance-containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules together with at least one cleaning component.

Priority:

Inventor: BOBNOCK ROBERT STANLEY [US]

Title: Oligosaccharide Aldonic Acids and Their Topical Use

Applicant/Assignee:

Application No.: 12/643215   Filing Date: 21/Dec/2009

Abstract:Methods for using compositions comprising oligosaccharide aldonic acids for general care, as well as for treatment and prevention, of various cosmetic conditions and dermatological disorders, including those associated with intrinsic and/or extrinsic aging, as well as with changes or damage caused by extrinsic factors

general care, as well as treatment and prevention of diseases and conditions, of the oral, and vaginal mucosa

for general oral care, as well as treatment and prevention of oral and gum diseases

and for wound healing of the skin. Methods may comprise using compositions comprising oligosaccharide aldonic acids and additional cosmetic, pharmaceutical or other topical agents to enhance or create synergetic effects.

Priority: US2007-872459 Applic. Date: 2007-10-15; US2004-811998 Applic. Date: 2004-03-30; US2001-987023 Applic. Date: 2001-11-13; US2000-487228 Applic. Date: 2000-01-19; US19990141264P Applic. Date: 1999-06-30

Inventor: YU RUEY J [US]; VAN SCOTT EUGENE J [US]

Title: METHODS OF MODULATING PPAR GAMMA-TYPE RECEPTORS

Applicant/Assignee: GALDERMA RESEARCH & DEVELOPMENT

Application No.: 12/562665   Filing Date: 18/Sep/2009

Abstract:Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.

Priority: FR20030007487 Applic. Date: 2003-06-20; US2005-311449 Applic. Date: 2005-12-20; WO2004EP07200 Applic. Date: 2004-06-16; US20030489672P Applic. Date: 2003-07-24

Inventor: CLARY LAURENCE [FR]; THOREAU ETIENNE [FR]; RIVIER MICHEL [FR]; AUBERT JEROME [FR]; CHANTALAT LAURENT [FR]; VOEGEL JOHANNES [FR]

Title: Compositions for Improving Skin Conditions Comprising Matrine or Its Oxidized Derivatives

Applicant/Assignee: BIOSPECTRUM INC

Application No.: 12/527237   Filing Date: 21/Feb/2008

Abstract:The present invention relates to a composition for improving skin conditions comprising matrine and oxymatrine as an active ingredient. Matrine and oxymatrine have lower cytotoxicity than retinol used as anti-wrinkle agents and exhibit the inhibition effect on collagenase activity and promotion effect on collagen biosynthesis at a molecular level, contributing to excellent efficacy in improvement of skin wrinkles. In addition, both matrine and oxymatrine exhibit the inhibition effect on melanin production by inhibiting intracellular tyrosinase activity, the improving effects of UV-induced skin damage and the skin growth promotion or hair loss prevention. Therefore, matrine and oxymatrine have the excellent improvement effects on skin conditions. Furthermore, matrine and oxymatrine have the excellent anti-obesity and anti-oxidation effects. The composition of this invention can be applied to cosmetic, pharmaceutical and food composition having no cytotoxicities and side effects.

Priority: KR20070017400 Applic. Date: 2007-02-21; WO2008KR01021 Applic. Date: 2008-02-21

Inventor: PARK DEOK HOON [KR]; JUNG EUN SUN [KR]; LEE JONG SUNG [KR]

Title: Amino acid and peptide conjugates of arylalkylic acids for cosmetic use

Applicant/Assignee: DSM IP ASSETS B.V

Application No.: 12/591663   Filing Date: 27/Nov/2009

Abstract:The invention provides novel compounds of general formula I wherein R1, R2 and R3 are independently hydrogen, OR4, C1-C6 alkyl or C2-C6 alkenyl, R4 is hydrogen, C1-C6 alkyl or C2-C6 alkenyl, -N-(AA) represents the residue of an amino acid or of a peptide which is bonded over the N-terminus of the amino acid or the peptide and the peptide is composed of 2 to 6, that means 2, 3, 4, 5 or 6, amino acids, wherein the C-terminus of the amino acid or the peptide is optionally esterified with a C1-C16 hydrocarbon moiety and n is an integer of 1 to 5. The compounds are in particular useful for cosmetic applications.

Priority: EP20040007282 Applic. Date: 2004-03-26; US2005-593484 Applic. Date: 2005-03-23; WO2005EP03116 Applic. Date: 2005-03-23

Inventor: KLOCK JOCHEN [DE]; MAILLAN PHILIPPE EMMANDEL [FR]; VOLLHARDT JUERGEN H [CH]; BEUMER RAPHAEL [DE]

Title: Microbe Reductions with Photosensitizers

Applicant/Assignee: CERAMOPTEC INDUSTRIES INC

Application No.: 12/643467   Filing Date: 21/Dec/2009

Abstract:Methods, devices and composition are disclosed for treating oral, skin and nail diseases, including inflammatory periodontal disease, onychomycosis and dermatophytosis. In a preferred embodiment a method for treating oral, skin and nail infections comprises administering a photosensitizing compound in long term effect or timed release formulations, including local highly concentrated formulations, and activating the photosensitizer with radiation to selectively destroy bacteria, fungi and other microbial bodies. In another preferred embodiment, photosensitizers are housed within nanoparticles, and can be gradually released through biodegradation or periodically released by such processes as brushing, irradiation and chemically induced release. The diffusion speed of the photosensitizers can be accelerated by brushing. In another embodiment, the photosensitizer molecule is also modified to more effectively target the molecule to the unwanted oral bacterial and fungal species. In another embodiment devices for treating oral, skin and nail infections includes a laser radiation source and delivery apparatuses such as brush or teethed comb for nail and scalp infections respectively.

Priority: US2006-523203 Applic. Date: 2006-09-19; US2002-241958 Applic. Date: 2002-09-12

Inventor: DRISCOLL TIM [US]; MEGA VERONICA INES [AR]; NEUBERGER WOLFGANG [AE]

Title: Device and method for wound therapy

Applicant/Assignee:

Application No.: 12/592049   Filing Date: 18/Nov/2009

Abstract:A wound therapy device is disclosed. The wound therapy device may include a housing for covering at least a portion of a wound and for sealing to a body surface of a patient. The housing may also include a liquid collector for retaining liquid therein and a vacuum connection for coupling to a vacuum source. The vacuum connection may be in gaseous communication with the liquid collector. The vacuum connection may be separated from the liquid collector by a liquid barrier.

Priority: US2006-610458 Applic. Date: 2006-12-13; US2006-432855 Applic. Date: 2006-05-11

Inventor: JOSHI ASHOK V [US]; GORDON JOHN HOWARD [US]; BHAVARAJU SAI [US]; DAYTON TROY C [US]; HEISER JEREMY [US]

Title: CONTROLLED BIOTHERMOTHERAPY

Applicant/Assignee:

Application No.: 12/256057   Filing Date: 22/Oct/2008

Abstract:A method for thermotherapy of a biological tissue by determining the temperature at which to heat a target site to be treated to provide a temperature to the site to effect therapy, the temperature above body temperature but below a protein denaturation temperature, as determined by a patient's experience of a sensation of pain. Thermotherapy is effected in the absence of coagulative effects by providing oscillatory energy at the predetermined temperature.

Priority:

Inventor: PEYMAN GHOLAM A [US]

Title: Methods of Assessing Risk Based on Medical Data and Uses Thereof

Applicant/Assignee: ROTHMAN HEALTHCARE RESEARCH, LLC

Application No.: 12/582942   Filing Date: 21/Oct/2009

Abstract:Methods of assessing risk based on medical data are disclosed herein. In an embodiment, a method of assessing risk associated with medical data includes creating a dataset representing a plurality of patients, the dataset comprising (x,y) pairs for each patient, wherein x represents the medical data collected at a first time, and wherein y is an outcome measurement collected at a second time

binning the (x,y) pairs to form a plurality of binned data sets

computing an average value for x and an average value for y for each binned data set

determining a minimum average value of y based on all of the average values of y

subtracting the minimum average value of y from each average value of y to get a new average value of y for each binned data set

and deriving a function for assessing risk associated with the medical data.

Priority: US20080107021P Applic. Date: 2008-10-21; US20080107028P Applic. Date: 2008-10-21

Inventor: ROTHMAN MICHAEL J [US]; ROTHMAN STEVEN I [US]

Title: Composition for matte layer formation, release sheet using the same, and synthetic leather produced using said release sheet

Applicant/Assignee: DAI NIPPON PRINTING CO., LTD

Application No.: 12/654689   Filing Date: 29/Dec/2009

Abstract:There are provided a composition for matte layer formation suitable for the production of a matte synthetic leather having a matte surface with a high level of jet-blackness even without the practice of embossing, raising, etc., and a release sheet for the production of a matte synthetic leather by using the composition. The composition for matte layer formation suitable for the production of a matte synthetic leather comprises a thermosetting resin and a matting agent as indispensable components. The matting agent comprises one or at least two types of organic or/and inorganic porous fine particles. The porous fine particles have a mean particle diameter in the range of 0.5 to 20 [mu]m and a specific surface area in the range of 1 to 1000 m2/g. The release sheet is produced by using the composition.

Priority: JP20020283538 Applic. Date: 2002-09-27; US2008-068633 Applic. Date: 2008-02-08; US2006-519805 Applic. Date: 2006-09-13; US2002-328188 Applic. Date: 2002-12-26

Inventor: SUTO KENICHIRO [JP]; KAWAGOE YOSHIKI [JP]; WATANABE HIROSHI [JP]; KUBOTA TAKESHI [JP]; MATSUDAIRA KOICHIRO [JP]

Title: USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS

Applicant/Assignee:

Application No.: 12/159363   Filing Date: 29/Dec/2006

Abstract:There is provided the use as reducing agents of alpha-hydroxycarbonyl compounds capable of forming cyclic dimers. There is also provided corresponding methods of reducing reducible compounds, particularly reduction-activated prodrugs. Examples of the alpha-hydroxycarbonyl compounds used are dihydroxyacetone, glycolaldehyde, glyceraldehyde, erythrose, xylulose, erythrulose or 3-hydroxy-2-butanone.

Priority: GB20050026552 Applic. Date: 2005-12-29; WO2006GB04947 Applic. Date: 2006-12-29

Inventor: KNOX RICHARD J [GB]

Title: COMPOSTION FOR SKIN EXTERNAL USE CONTAINING OMEGA-3 FATTY ACID

Applicant/Assignee: AMOREPACIFIC CORPORATION

Application No.: 12/683916   Filing Date: 07/Jan/2010

Abstract:Stable preparations containing omega-3 fatty acid as an effective ingredient are disclosed. Further, uses of omega-3 fatty acid in preventing or alleviating skin aging, moisturizing skin, improving skin roughness, restoring or strengthening skin barrier function, improving skin elasticity, recovering or preventing skin damage induced by UV are disclosed.

Priority: KR20060084425 Applic. Date: 2006-09-01; US2007-928669 Applic. Date: 2007-10-30; US2007-840512 Applic. Date: 2007-08-17

Inventor: CHO JUNCHEOL [KR]; KANG CHANKOO [KR]; HAN SANGHOON [KR]; SON EUI-DONG [KR]; KANG HAKHEE [KR]

Title: STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS

Applicant/Assignee: CIBA CORPORATION

Application No.: 12/520880   Filing Date: 16/Jan/2008

Abstract:Disclosed is the use of merocyanine derivatives of formula (1) for stabilizing UV-sensitive active ingredients like dibenzoylmethane derivatives.

Priority: EP20070101171 Applic. Date: 2007-01-25; WO2008EP50440 Applic. Date: 2008-01-16

Inventor: WAGNER BARBARA [DE]; HERZOG BERND [DE]; MULLER STEFAN [DE]; EHLIS THOMAS [DE]

Title: COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING ARCTIIN, ARCTIGENIN OR THE MIXTURE THEREOF AS ACTIVE

Applicant/Assignee:

Application No.: 12/449727   Filing Date: 25/Feb/2008

Abstract:Present Invention relates to a skin whitening cosmetic composition comprising arctiin, arctigenin or a mixture thereof as an active ingredient. The disclosed composition can control or inhibit the synthesis of melanin by acting on a melanin synthesis route of [alpha]-MSH secreted by UV, and thus show an excellent whitening effect compared to a conventional skin whitening cosmetic. Also, the composition has high formulation stability and low skin irritation.

Priority: KR20070020603 Applic. Date: 2007-02-28; WO2008KR01077 Applic. Date: 2008-02-25

Inventor: LEE JUNG NOH [KR]; CHOI JEONG EUN [KR]; KIM SANG WOO [KR]; LEE KANG TAE [KR]; LEE KUN KOOK [KR]

Title: Color cosmetics comprising a random terpolymer

Applicant/Assignee:

Application No.: 12/566273   Filing Date: 24/Sep/2009

Abstract:Topically applicable, water-resistant cosmetic or dermatological compositions well suited for the cosmetic color compositions for human skin and/or hair comprising at least one (a) coloring agent

(b) at least one random terpolymer

and, optionally (c) other cosmetically acceptable ingredients.

Priority: US20080194877P Applic. Date: 2008-10-01

Inventor: DUEVA-KOGANOV OLGA V [US]; JAYNES BINGHAM S [US]; LUPIA JOSEPH A [US]; TERMATEN ARJAN T [NL]; SLUIS MARCELLES VAN DER [NL]; SUURMEIJER MARLEEN [NL]; NORMINGTON DAVID [GB]; SCHNYDER MARCEL [CH]